Amino acid dipepetide frequency for Odocoileus adenovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.063AlaAla: 3.063 ± 0.594
0.985AlaCys: 0.985 ± 0.395
1.86AlaAsp: 1.86 ± 0.545
1.86AlaGlu: 1.86 ± 0.376
2.735AlaPhe: 2.735 ± 0.475
1.75AlaGly: 1.75 ± 0.502
0.875AlaHis: 0.875 ± 0.303
3.501AlaIle: 3.501 ± 0.483
3.391AlaLys: 3.391 ± 0.561
5.251AlaLeu: 5.251 ± 0.886
1.313AlaMet: 1.313 ± 0.412
3.391AlaAsn: 3.391 ± 0.782
1.969AlaPro: 1.969 ± 0.438
1.75AlaGln: 1.75 ± 0.331
1.86AlaArg: 1.86 ± 0.508
3.501AlaSer: 3.501 ± 0.782
3.61AlaThr: 3.61 ± 0.647
2.844AlaVal: 2.844 ± 0.679
0.438AlaTrp: 0.438 ± 0.22
2.626AlaTyr: 2.626 ± 0.44
0.0AlaXaa: 0.0 ± 0.0
Cys
0.656CysAla: 0.656 ± 0.282
0.547CysCys: 0.547 ± 0.29
1.094CysAsp: 1.094 ± 0.342
1.532CysGlu: 1.532 ± 0.546
1.532CysPhe: 1.532 ± 0.513
1.422CysGly: 1.422 ± 0.351
0.985CysHis: 0.985 ± 0.426
1.203CysIle: 1.203 ± 0.469
1.75CysLys: 1.75 ± 0.573
2.188CysLeu: 2.188 ± 0.703
0.547CysMet: 0.547 ± 0.239
1.313CysAsn: 1.313 ± 0.486
1.203CysPro: 1.203 ± 0.436
0.766CysGln: 0.766 ± 0.295
1.203CysArg: 1.203 ± 0.51
2.079CysSer: 2.079 ± 0.52
0.875CysThr: 0.875 ± 0.32
0.656CysVal: 0.656 ± 0.337
0.328CysTrp: 0.328 ± 0.157
0.656CysTyr: 0.656 ± 0.229
0.0CysXaa: 0.0 ± 0.0
Asp
1.969AspAla: 1.969 ± 0.508
1.75AspCys: 1.75 ± 0.504
2.407AspAsp: 2.407 ± 0.582
3.282AspGlu: 3.282 ± 0.619
2.844AspPhe: 2.844 ± 0.426
2.079AspGly: 2.079 ± 0.484
1.422AspHis: 1.422 ± 0.389
4.485AspIle: 4.485 ± 0.8
2.844AspLys: 2.844 ± 0.527
4.595AspLeu: 4.595 ± 0.711
0.985AspMet: 0.985 ± 0.341
2.954AspAsn: 2.954 ± 0.598
3.173AspPro: 3.173 ± 0.703
1.313AspGln: 1.313 ± 0.288
2.516AspArg: 2.516 ± 0.557
3.063AspSer: 3.063 ± 0.446
2.735AspThr: 2.735 ± 0.452
2.516AspVal: 2.516 ± 0.517
0.438AspTrp: 0.438 ± 0.223
1.203AspTyr: 1.203 ± 0.388
0.0AspXaa: 0.0 ± 0.0
Glu
2.954GluAla: 2.954 ± 0.795
1.86GluCys: 1.86 ± 0.485
3.61GluAsp: 3.61 ± 0.552
5.798GluGlu: 5.798 ± 1.29
2.188GluPhe: 2.188 ± 0.474
3.173GluGly: 3.173 ± 0.649
0.656GluHis: 0.656 ± 0.249
4.813GluIle: 4.813 ± 0.65
5.142GluLys: 5.142 ± 1.308
3.063GluLeu: 3.063 ± 0.507
1.313GluMet: 1.313 ± 0.455
3.938GluAsn: 3.938 ± 0.578
2.297GluPro: 2.297 ± 0.7
2.297GluGln: 2.297 ± 0.514
2.407GluArg: 2.407 ± 0.84
3.501GluSer: 3.501 ± 0.793
4.595GluThr: 4.595 ± 0.934
2.297GluVal: 2.297 ± 0.55
1.094GluTrp: 1.094 ± 0.378
1.203GluTyr: 1.203 ± 0.383
0.0GluXaa: 0.0 ± 0.0
Phe
2.297PheAla: 2.297 ± 0.444
1.422PheCys: 1.422 ± 0.491
2.844PheAsp: 2.844 ± 0.507
2.516PheGlu: 2.516 ± 0.386
3.063PhePhe: 3.063 ± 0.769
1.86PheGly: 1.86 ± 0.551
2.079PheHis: 2.079 ± 0.429
4.376PheIle: 4.376 ± 0.763
4.595PheLys: 4.595 ± 0.969
4.595PheLeu: 4.595 ± 0.713
1.422PheMet: 1.422 ± 0.547
3.173PheAsn: 3.173 ± 0.506
2.954PhePro: 2.954 ± 0.577
2.735PheGln: 2.735 ± 0.562
2.407PheArg: 2.407 ± 0.516
3.61PheSer: 3.61 ± 0.529
3.063PheThr: 3.063 ± 0.465
3.282PheVal: 3.282 ± 0.662
0.547PheTrp: 0.547 ± 0.278
2.844PheTyr: 2.844 ± 0.499
0.0PheXaa: 0.0 ± 0.0
Gly
3.391GlyAla: 3.391 ± 0.607
0.985GlyCys: 0.985 ± 0.456
2.735GlyAsp: 2.735 ± 0.778
2.297GlyGlu: 2.297 ± 0.537
2.516GlyPhe: 2.516 ± 0.523
2.735GlyGly: 2.735 ± 0.542
1.75GlyHis: 1.75 ± 0.484
3.829GlyIle: 3.829 ± 0.433
3.282GlyLys: 3.282 ± 0.751
4.266GlyLeu: 4.266 ± 0.936
0.656GlyMet: 0.656 ± 0.244
3.938GlyAsn: 3.938 ± 0.897
1.641GlyPro: 1.641 ± 0.369
2.844GlyGln: 2.844 ± 0.767
3.282GlyArg: 3.282 ± 0.914
3.501GlySer: 3.501 ± 0.516
2.626GlyThr: 2.626 ± 0.526
2.407GlyVal: 2.407 ± 0.618
0.656GlyTrp: 0.656 ± 0.294
1.422GlyTyr: 1.422 ± 0.453
0.0GlyXaa: 0.0 ± 0.0
His
0.985HisAla: 0.985 ± 0.352
1.75HisCys: 1.75 ± 0.51
0.875HisAsp: 0.875 ± 0.346
0.438HisGlu: 0.438 ± 0.22
1.75HisPhe: 1.75 ± 0.408
1.313HisGly: 1.313 ± 0.504
0.766HisHis: 0.766 ± 0.349
1.203HisIle: 1.203 ± 0.391
0.766HisLys: 0.766 ± 0.276
3.282HisLeu: 3.282 ± 0.601
0.328HisMet: 0.328 ± 0.169
1.313HisAsn: 1.313 ± 0.46
1.313HisPro: 1.313 ± 0.327
1.094HisGln: 1.094 ± 0.454
0.985HisArg: 0.985 ± 0.301
1.75HisSer: 1.75 ± 0.466
1.094HisThr: 1.094 ± 0.291
1.422HisVal: 1.422 ± 0.343
0.219HisTrp: 0.219 ± 0.159
1.203HisTyr: 1.203 ± 0.308
0.0HisXaa: 0.0 ± 0.0
Ile
3.61IleAla: 3.61 ± 0.533
2.079IleCys: 2.079 ± 0.474
2.844IleAsp: 2.844 ± 0.628
3.938IleGlu: 3.938 ± 0.763
3.063IlePhe: 3.063 ± 0.637
3.938IleGly: 3.938 ± 0.726
0.766IleHis: 0.766 ± 0.263
3.61IleIle: 3.61 ± 0.641
5.032IleLys: 5.032 ± 0.67
6.126IleLeu: 6.126 ± 1.074
0.656IleMet: 0.656 ± 0.284
4.266IleAsn: 4.266 ± 0.62
4.376IlePro: 4.376 ± 0.904
3.61IleGln: 3.61 ± 0.962
2.188IleArg: 2.188 ± 0.688
5.47IleSer: 5.47 ± 0.831
7.548IleThr: 7.548 ± 0.765
2.188IleVal: 2.188 ± 0.376
1.094IleTrp: 1.094 ± 0.284
2.188IleTyr: 2.188 ± 0.33
0.0IleXaa: 0.0 ± 0.0
Lys
2.407LysAla: 2.407 ± 0.576
1.422LysCys: 1.422 ± 0.464
2.844LysAsp: 2.844 ± 0.55
3.72LysGlu: 3.72 ± 1.105
3.063LysPhe: 3.063 ± 0.566
3.501LysGly: 3.501 ± 0.396
1.422LysHis: 1.422 ± 0.379
5.032LysIle: 5.032 ± 0.808
5.251LysLys: 5.251 ± 1.032
6.345LysLeu: 6.345 ± 1.239
1.86LysMet: 1.86 ± 0.579
4.048LysAsn: 4.048 ± 1.026
2.516LysPro: 2.516 ± 0.55
2.844LysGln: 2.844 ± 0.629
4.704LysArg: 4.704 ± 0.782
4.595LysSer: 4.595 ± 0.864
3.501LysThr: 3.501 ± 0.573
2.844LysVal: 2.844 ± 0.557
1.75LysTrp: 1.75 ± 0.413
2.626LysTyr: 2.626 ± 0.401
0.0LysXaa: 0.0 ± 0.0
Leu
4.048LeuAla: 4.048 ± 0.611
1.313LeuCys: 1.313 ± 0.385
4.376LeuAsp: 4.376 ± 0.538
5.47LeuGlu: 5.47 ± 0.82
4.595LeuPhe: 4.595 ± 0.943
3.829LeuGly: 3.829 ± 0.465
2.954LeuHis: 2.954 ± 0.601
5.579LeuIle: 5.579 ± 0.985
8.095LeuLys: 8.095 ± 1.177
8.971LeuLeu: 8.971 ± 1.251
2.516LeuMet: 2.516 ± 0.534
7.111LeuAsn: 7.111 ± 1.105
4.704LeuPro: 4.704 ± 0.465
4.485LeuGln: 4.485 ± 0.625
3.829LeuArg: 3.829 ± 0.773
7.658LeuSer: 7.658 ± 1.253
7.33LeuThr: 7.33 ± 1.261
3.173LeuVal: 3.173 ± 0.575
0.875LeuTrp: 0.875 ± 0.29
3.829LeuTyr: 3.829 ± 0.599
0.0LeuXaa: 0.0 ± 0.0
Met
1.422MetAla: 1.422 ± 0.296
0.109MetCys: 0.109 ± 0.109
1.313MetAsp: 1.313 ± 0.268
0.985MetGlu: 0.985 ± 0.323
0.985MetPhe: 0.985 ± 0.246
1.313MetGly: 1.313 ± 0.438
0.328MetHis: 0.328 ± 0.168
0.985MetIle: 0.985 ± 0.253
1.203MetLys: 1.203 ± 0.5
1.641MetLeu: 1.641 ± 0.351
0.219MetMet: 0.219 ± 0.168
1.641MetAsn: 1.641 ± 0.381
1.094MetPro: 1.094 ± 0.323
1.422MetGln: 1.422 ± 0.42
0.656MetArg: 0.656 ± 0.249
1.313MetSer: 1.313 ± 0.401
0.875MetThr: 0.875 ± 0.291
0.656MetVal: 0.656 ± 0.248
0.656MetTrp: 0.656 ± 0.254
1.422MetTyr: 1.422 ± 0.388
0.0MetXaa: 0.0 ± 0.0
Asn
4.704AsnAla: 4.704 ± 0.612
1.313AsnCys: 1.313 ± 0.351
3.173AsnAsp: 3.173 ± 0.443
3.391AsnGlu: 3.391 ± 0.602
4.923AsnPhe: 4.923 ± 0.768
2.297AsnGly: 2.297 ± 0.466
1.75AsnHis: 1.75 ± 0.513
5.798AsnIle: 5.798 ± 0.711
2.844AsnLys: 2.844 ± 0.738
5.032AsnLeu: 5.032 ± 0.834
1.203AsnMet: 1.203 ± 0.427
4.157AsnAsn: 4.157 ± 0.564
3.391AsnPro: 3.391 ± 0.561
3.501AsnGln: 3.501 ± 0.6
2.844AsnArg: 2.844 ± 0.438
3.61AsnSer: 3.61 ± 0.984
3.829AsnThr: 3.829 ± 0.596
4.048AsnVal: 4.048 ± 0.804
0.656AsnTrp: 0.656 ± 0.319
3.501AsnTyr: 3.501 ± 0.867
0.0AsnXaa: 0.0 ± 0.0
Pro
1.75ProAla: 1.75 ± 0.365
0.547ProCys: 0.547 ± 0.368
2.297ProAsp: 2.297 ± 0.588
3.501ProGlu: 3.501 ± 0.419
4.266ProPhe: 4.266 ± 0.414
1.422ProGly: 1.422 ± 0.321
0.985ProHis: 0.985 ± 0.36
3.501ProIle: 3.501 ± 0.657
2.626ProLys: 2.626 ± 0.472
5.032ProLeu: 5.032 ± 1.114
1.641ProMet: 1.641 ± 0.378
3.173ProAsn: 3.173 ± 0.823
3.61ProPro: 3.61 ± 0.617
2.079ProGln: 2.079 ± 0.505
1.641ProArg: 1.641 ± 0.485
3.829ProSer: 3.829 ± 0.478
2.516ProThr: 2.516 ± 0.443
3.282ProVal: 3.282 ± 0.74
0.656ProTrp: 0.656 ± 0.232
1.86ProTyr: 1.86 ± 0.504
0.0ProXaa: 0.0 ± 0.0
Gln
1.969GlnAla: 1.969 ± 0.424
1.532GlnCys: 1.532 ± 0.666
2.188GlnAsp: 2.188 ± 0.464
2.188GlnGlu: 2.188 ± 0.588
1.532GlnPhe: 1.532 ± 0.383
1.969GlnGly: 1.969 ± 0.495
0.985GlnHis: 0.985 ± 0.289
3.173GlnIle: 3.173 ± 0.714
3.173GlnLys: 3.173 ± 0.426
5.47GlnLeu: 5.47 ± 0.82
1.422GlnMet: 1.422 ± 0.349
2.735GlnAsn: 2.735 ± 0.607
3.063GlnPro: 3.063 ± 0.663
1.75GlnGln: 1.75 ± 0.455
2.844GlnArg: 2.844 ± 0.567
2.735GlnSer: 2.735 ± 0.61
2.297GlnThr: 2.297 ± 0.525
2.079GlnVal: 2.079 ± 0.587
0.766GlnTrp: 0.766 ± 0.205
1.094GlnTyr: 1.094 ± 0.337
0.109GlnXaa: 0.109 ± 0.116
Arg
2.079ArgAla: 2.079 ± 0.63
0.875ArgCys: 0.875 ± 0.355
2.188ArgAsp: 2.188 ± 0.596
2.735ArgGlu: 2.735 ± 0.642
1.86ArgPhe: 1.86 ± 0.509
2.626ArgGly: 2.626 ± 0.493
0.656ArgHis: 0.656 ± 0.205
3.282ArgIle: 3.282 ± 0.596
3.501ArgLys: 3.501 ± 0.688
3.829ArgLeu: 3.829 ± 0.839
0.766ArgMet: 0.766 ± 0.312
3.829ArgAsn: 3.829 ± 0.638
1.422ArgPro: 1.422 ± 0.324
1.313ArgGln: 1.313 ± 0.485
2.954ArgArg: 2.954 ± 0.962
2.954ArgSer: 2.954 ± 0.41
2.626ArgThr: 2.626 ± 0.474
1.86ArgVal: 1.86 ± 0.425
1.094ArgTrp: 1.094 ± 0.244
1.641ArgTyr: 1.641 ± 0.396
0.109ArgXaa: 0.109 ± 0.105
Ser
3.501SerAla: 3.501 ± 0.663
1.313SerCys: 1.313 ± 0.521
3.173SerAsp: 3.173 ± 0.712
5.579SerGlu: 5.579 ± 0.604
4.704SerPhe: 4.704 ± 0.827
4.813SerGly: 4.813 ± 0.734
1.532SerHis: 1.532 ± 0.445
4.595SerIle: 4.595 ± 0.825
4.813SerLys: 4.813 ± 0.94
8.205SerLeu: 8.205 ± 1.217
1.203SerMet: 1.203 ± 0.258
3.829SerAsn: 3.829 ± 0.582
2.954SerPro: 2.954 ± 0.773
3.72SerGln: 3.72 ± 0.735
1.969SerArg: 1.969 ± 0.481
6.345SerSer: 6.345 ± 0.781
3.282SerThr: 3.282 ± 0.572
3.173SerVal: 3.173 ± 0.515
1.094SerTrp: 1.094 ± 0.324
2.297SerTyr: 2.297 ± 0.432
0.0SerXaa: 0.0 ± 0.0
Thr
4.266ThrAla: 4.266 ± 0.597
0.547ThrCys: 0.547 ± 0.271
2.954ThrAsp: 2.954 ± 0.549
3.829ThrGlu: 3.829 ± 0.508
3.173ThrPhe: 3.173 ± 0.484
4.376ThrGly: 4.376 ± 0.601
1.532ThrHis: 1.532 ± 0.337
4.376ThrIle: 4.376 ± 0.631
2.626ThrLys: 2.626 ± 0.557
6.017ThrLeu: 6.017 ± 0.702
0.547ThrMet: 0.547 ± 0.234
3.829ThrAsn: 3.829 ± 0.758
2.844ThrPro: 2.844 ± 0.549
2.735ThrGln: 2.735 ± 0.351
2.735ThrArg: 2.735 ± 0.679
4.048ThrSer: 4.048 ± 0.598
4.157ThrThr: 4.157 ± 0.992
4.157ThrVal: 4.157 ± 0.823
0.875ThrTrp: 0.875 ± 0.282
2.954ThrTyr: 2.954 ± 0.669
0.0ThrXaa: 0.0 ± 0.0
Val
2.188ValAla: 2.188 ± 0.602
0.656ValCys: 0.656 ± 0.305
2.844ValAsp: 2.844 ± 0.688
2.516ValGlu: 2.516 ± 0.419
2.844ValPhe: 2.844 ± 0.5
2.407ValGly: 2.407 ± 0.485
0.985ValHis: 0.985 ± 0.345
2.844ValIle: 2.844 ± 0.517
2.844ValLys: 2.844 ± 0.695
4.813ValLeu: 4.813 ± 0.553
0.547ValMet: 0.547 ± 0.27
3.501ValAsn: 3.501 ± 0.578
2.735ValPro: 2.735 ± 0.472
2.079ValGln: 2.079 ± 0.495
1.422ValArg: 1.422 ± 0.331
3.391ValSer: 3.391 ± 0.703
3.391ValThr: 3.391 ± 0.669
3.063ValVal: 3.063 ± 0.584
0.547ValTrp: 0.547 ± 0.276
2.188ValTyr: 2.188 ± 0.473
0.0ValXaa: 0.0 ± 0.0
Trp
0.328TrpAla: 0.328 ± 0.16
0.328TrpCys: 0.328 ± 0.178
0.656TrpAsp: 0.656 ± 0.228
0.656TrpGlu: 0.656 ± 0.306
0.875TrpPhe: 0.875 ± 0.308
1.094TrpGly: 1.094 ± 0.312
0.219TrpHis: 0.219 ± 0.178
0.656TrpIle: 0.656 ± 0.228
1.203TrpLys: 1.203 ± 0.417
0.766TrpLeu: 0.766 ± 0.262
0.219TrpMet: 0.219 ± 0.159
0.985TrpAsn: 0.985 ± 0.377
1.094TrpPro: 1.094 ± 0.337
0.766TrpGln: 0.766 ± 0.279
0.547TrpArg: 0.547 ± 0.187
1.75TrpSer: 1.75 ± 0.343
1.313TrpThr: 1.313 ± 0.409
0.328TrpVal: 0.328 ± 0.161
0.219TrpTrp: 0.219 ± 0.148
0.875TrpTyr: 0.875 ± 0.384
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.985TyrAla: 0.985 ± 0.371
1.203TyrCys: 1.203 ± 0.358
2.297TyrAsp: 2.297 ± 0.493
1.969TyrGlu: 1.969 ± 0.396
3.173TyrPhe: 3.173 ± 0.517
2.844TyrGly: 2.844 ± 0.684
1.203TyrHis: 1.203 ± 0.299
1.75TyrIle: 1.75 ± 0.343
1.203TyrLys: 1.203 ± 0.451
5.142TyrLeu: 5.142 ± 0.624
0.766TyrMet: 0.766 ± 0.246
2.844TyrAsn: 2.844 ± 0.53
1.86TyrPro: 1.86 ± 0.5
1.969TyrGln: 1.969 ± 0.546
1.203TyrArg: 1.203 ± 0.281
3.391TyrSer: 3.391 ± 0.802
1.313TyrThr: 1.313 ± 0.358
1.641TyrVal: 1.641 ± 0.316
0.875TyrTrp: 0.875 ± 0.326
1.313TyrTyr: 1.313 ± 0.348
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.109XaaLys: 0.109 ± 0.105
0.109XaaLeu: 0.109 ± 0.116
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 27 proteins (9142 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski