Amino acid dipepetide frequency for Pseudomonas resinovorans NBRC 106553

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.482AlaAla: 13.482 ± 0.136	1.255AlaCys: 1.255 ± 0.028	6.119AlaAsp: 6.119 ± 0.057	7.675AlaGlu: 7.675 ± 0.08	4.028AlaPhe: 4.028 ± 0.052	9.79AlaGly: 9.79 ± 0.101	2.141AlaHis: 2.141 ± 0.034	5.141AlaIle: 5.141 ± 0.066	3.601AlaLys: 3.601 ± 0.056	14.073AlaLeu: 14.073 ± 0.126	2.968AlaMet: 2.968 ± 0.043	3.133AlaAsn: 3.133 ± 0.05	4.973AlaPro: 4.973 ± 0.058	4.773AlaGln: 4.773 ± 0.059	7.868AlaArg: 7.868 ± 0.08	6.243AlaSer: 6.243 ± 0.073	4.931AlaThr: 4.931 ± 0.067	7.563AlaVal: 7.563 ± 0.082	1.702AlaTrp: 1.702 ± 0.03	2.589AlaTyr: 2.589 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.106CysAla: 1.106 ± 0.023	0.154CysCys: 0.154 ± 0.009	0.504CysAsp: 0.504 ± 0.016	0.543CysGlu: 0.543 ± 0.018	0.349CysPhe: 0.349 ± 0.013	0.956CysGly: 0.956 ± 0.022	0.302CysHis: 0.302 ± 0.015	0.415CysIle: 0.415 ± 0.015	0.27CysLys: 0.27 ± 0.014	1.12CysLeu: 1.12 ± 0.025	0.192CysMet: 0.192 ± 0.01	0.249CysAsn: 0.249 ± 0.012	0.512CysPro: 0.512 ± 0.019	0.395CysGln: 0.395 ± 0.014	0.675CysArg: 0.675 ± 0.019	0.558CysSer: 0.558 ± 0.018	0.439CysThr: 0.439 ± 0.018	0.679CysVal: 0.679 ± 0.02	0.146CysTrp: 0.146 ± 0.008	0.264CysTyr: 0.264 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.118AspAla: 6.118 ± 0.062	0.555AspCys: 0.555 ± 0.02	2.959AspAsp: 2.959 ± 0.051	3.497AspGlu: 3.497 ± 0.048	2.204AspPhe: 2.204 ± 0.032	4.883AspGly: 4.883 ± 0.073	1.119AspHis: 1.119 ± 0.026	2.57AspIle: 2.57 ± 0.043	1.812AspLys: 1.812 ± 0.03	6.192AspLeu: 6.192 ± 0.058	1.176AspMet: 1.176 ± 0.024	1.625AspAsn: 1.625 ± 0.044	2.966AspPro: 2.966 ± 0.043	2.103AspGln: 2.103 ± 0.035	3.207AspArg: 3.207 ± 0.042	2.931AspSer: 2.931 ± 0.049	2.289AspThr: 2.289 ± 0.051	3.465AspVal: 3.465 ± 0.048	1.01AspTrp: 1.01 ± 0.023	1.722AspTyr: 1.722 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	6.952GluAla: 6.952 ± 0.074	0.426GluCys: 0.426 ± 0.016	2.599GluAsp: 2.599 ± 0.038	3.467GluGlu: 3.467 ± 0.057	1.908GluPhe: 1.908 ± 0.034	4.487GluGly: 4.487 ± 0.053	1.561GluHis: 1.561 ± 0.028	2.692GluIle: 2.692 ± 0.043	1.978GluLys: 1.978 ± 0.04	7.45GluLeu: 7.45 ± 0.078	1.343GluMet: 1.343 ± 0.027	1.543GluAsn: 1.543 ± 0.032	2.613GluPro: 2.613 ± 0.037	3.556GluGln: 3.556 ± 0.048	5.32GluArg: 5.32 ± 0.076	2.774GluSer: 2.774 ± 0.042	2.468GluThr: 2.468 ± 0.039	4.474GluVal: 4.474 ± 0.058	0.74GluTrp: 0.74 ± 0.021	1.172GluTyr: 1.172 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.117PheAla: 4.117 ± 0.046	0.456PheCys: 0.456 ± 0.016	2.503PheAsp: 2.503 ± 0.038	2.125PheGlu: 2.125 ± 0.032	1.423PhePhe: 1.423 ± 0.034	3.426PheGly: 3.426 ± 0.046	0.787PheHis: 0.787 ± 0.019	1.775PheIle: 1.775 ± 0.036	1.156PheLys: 1.156 ± 0.023	3.349PheLeu: 3.349 ± 0.048	0.762PheMet: 0.762 ± 0.021	1.318PheAsn: 1.318 ± 0.033	1.508PhePro: 1.508 ± 0.03	1.284PheGln: 1.284 ± 0.027	1.959PheArg: 1.959 ± 0.03	2.438PheSer: 2.438 ± 0.04	1.869PheThr: 1.869 ± 0.039	2.539PheVal: 2.539 ± 0.045	0.578PheTrp: 0.578 ± 0.02	1.073PheTyr: 1.073 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	8.144GlyAla: 8.144 ± 0.088	0.98GlyCys: 0.98 ± 0.022	4.314GlyAsp: 4.314 ± 0.067	5.187GlyGlu: 5.187 ± 0.057	3.46GlyPhe: 3.46 ± 0.041	6.837GlyGly: 6.837 ± 0.107	1.911GlyHis: 1.911 ± 0.035	4.128GlyIle: 4.128 ± 0.049	3.259GlyLys: 3.259 ± 0.042	9.899GlyLeu: 9.899 ± 0.084	2.238GlyMet: 2.238 ± 0.037	2.631GlyAsn: 2.631 ± 0.078	2.868GlyPro: 2.868 ± 0.041	3.788GlyGln: 3.788 ± 0.05	5.475GlyArg: 5.475 ± 0.061	4.829GlySer: 4.829 ± 0.087	4.014GlyThr: 4.014 ± 0.079	6.142GlyVal: 6.142 ± 0.069	1.398GlyTrp: 1.398 ± 0.028	2.505GlyTyr: 2.505 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.218HisAla: 2.218 ± 0.036	0.336HisCys: 0.336 ± 0.013	1.157HisAsp: 1.157 ± 0.024	1.18HisGlu: 1.18 ± 0.027	0.992HisPhe: 0.992 ± 0.024	2.06HisGly: 2.06 ± 0.041	0.614HisHis: 0.614 ± 0.019	0.916HisIle: 0.916 ± 0.02	0.603HisLys: 0.603 ± 0.016	2.604HisLeu: 2.604 ± 0.043	0.502HisMet: 0.502 ± 0.017	0.566HisAsn: 0.566 ± 0.018	1.397HisPro: 1.397 ± 0.031	0.907HisGln: 0.907 ± 0.02	1.361HisArg: 1.361 ± 0.028	1.212HisSer: 1.212 ± 0.024	0.861HisThr: 0.861 ± 0.025	1.292HisVal: 1.292 ± 0.028	0.455HisTrp: 0.455 ± 0.016	0.716HisTyr: 0.716 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.58IleAla: 5.58 ± 0.059	0.469IleCys: 0.469 ± 0.017	2.962IleAsp: 2.962 ± 0.041	3.081IleGlu: 3.081 ± 0.049	1.373IlePhe: 1.373 ± 0.029	4.393IleGly: 4.393 ± 0.058	0.963IleHis: 0.963 ± 0.018	1.779IleIle: 1.779 ± 0.036	1.475IleLys: 1.475 ± 0.034	3.973IleLeu: 3.973 ± 0.057	0.739IleMet: 0.739 ± 0.023	1.574IleAsn: 1.574 ± 0.033	2.25IlePro: 2.25 ± 0.037	1.551IleGln: 1.551 ± 0.026	2.905IleArg: 2.905 ± 0.042	2.756IleSer: 2.756 ± 0.041	2.349IleThr: 2.349 ± 0.046	2.802IleVal: 2.802 ± 0.041	0.505IleTrp: 0.505 ± 0.018	1.081IleTyr: 1.081 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	3.97LysAla: 3.97 ± 0.06	0.166LysCys: 0.166 ± 0.01	1.634LysAsp: 1.634 ± 0.031	1.619LysGlu: 1.619 ± 0.031	0.777LysPhe: 0.777 ± 0.02	2.572LysGly: 2.572 ± 0.038	0.703LysHis: 0.703 ± 0.02	1.281LysIle: 1.281 ± 0.028	1.127LysLys: 1.127 ± 0.031	3.611LysLeu: 3.611 ± 0.05	0.654LysMet: 0.654 ± 0.018	0.871LysAsn: 0.871 ± 0.025	1.958LysPro: 1.958 ± 0.044	1.359LysGln: 1.359 ± 0.031	2.262LysArg: 2.262 ± 0.038	1.629LysSer: 1.629 ± 0.03	1.592LysThr: 1.592 ± 0.031	2.707LysVal: 2.707 ± 0.038	0.334LysTrp: 0.334 ± 0.014	0.681LysTyr: 0.681 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.51LeuAla: 15.51 ± 0.138	1.218LeuCys: 1.218 ± 0.029	7.217LeuAsp: 7.217 ± 0.084	6.981LeuGlu: 6.981 ± 0.075	4.196LeuPhe: 4.196 ± 0.058	9.845LeuGly: 9.845 ± 0.084	2.414LeuHis: 2.414 ± 0.04	5.014LeuIle: 5.014 ± 0.061	4.115LeuLys: 4.115 ± 0.055	13.973LeuLeu: 13.973 ± 0.153	2.547LeuMet: 2.547 ± 0.032	3.369LeuAsn: 3.369 ± 0.047	6.515LeuPro: 6.515 ± 0.082	4.363LeuGln: 4.363 ± 0.057	7.871LeuArg: 7.871 ± 0.085	6.71LeuSer: 6.71 ± 0.072	5.443LeuThr: 5.443 ± 0.068	8.583LeuVal: 8.583 ± 0.076	1.394LeuTrp: 1.394 ± 0.032	2.591LeuTyr: 2.591 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.696MetAla: 2.696 ± 0.036	0.169MetCys: 0.169 ± 0.011	1.108MetAsp: 1.108 ± 0.027	0.994MetGlu: 0.994 ± 0.027	0.653MetPhe: 0.653 ± 0.018	1.703MetGly: 1.703 ± 0.032	0.461MetHis: 0.461 ± 0.017	1.059MetIle: 1.059 ± 0.024	0.834MetLys: 0.834 ± 0.022	2.619MetLeu: 2.619 ± 0.043	0.455MetMet: 0.455 ± 0.02	0.78MetAsn: 0.78 ± 0.022	1.312MetPro: 1.312 ± 0.027	1.007MetGln: 1.007 ± 0.024	1.528MetArg: 1.528 ± 0.029	1.627MetSer: 1.627 ± 0.031	1.375MetThr: 1.375 ± 0.029	1.568MetVal: 1.568 ± 0.033	0.182MetTrp: 0.182 ± 0.009	0.358MetTyr: 0.358 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.143AsnAla: 3.143 ± 0.051	0.276AsnCys: 0.276 ± 0.013	1.582AsnAsp: 1.582 ± 0.061	1.389AsnGlu: 1.389 ± 0.031	1.058AsnPhe: 1.058 ± 0.029	2.669AsnGly: 2.669 ± 0.066	0.577AsnHis: 0.577 ± 0.018	1.269AsnIle: 1.269 ± 0.031	0.773AsnLys: 0.773 ± 0.022	3.588AsnLeu: 3.588 ± 0.045	0.564AsnMet: 0.564 ± 0.018	0.893AsnAsn: 0.893 ± 0.031	1.98AsnPro: 1.98 ± 0.04	1.268AsnGln: 1.268 ± 0.03	1.939AsnArg: 1.939 ± 0.034	1.473AsnSer: 1.473 ± 0.037	1.344AsnThr: 1.344 ± 0.033	1.862AsnVal: 1.862 ± 0.046	0.488AsnTrp: 0.488 ± 0.019	0.821AsnTyr: 0.821 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.929ProAla: 5.929 ± 0.074	0.366ProCys: 0.366 ± 0.014	2.846ProAsp: 2.846 ± 0.039	3.604ProGlu: 3.604 ± 0.048	1.868ProPhe: 1.868 ± 0.033	4.28ProGly: 4.28 ± 0.053	1.011ProHis: 1.011 ± 0.025	1.934ProIle: 1.934 ± 0.034	1.494ProLys: 1.494 ± 0.03	5.933ProLeu: 5.933 ± 0.073	1.166ProMet: 1.166 ± 0.025	1.383ProAsn: 1.383 ± 0.027	2.124ProPro: 2.124 ± 0.04	2.19ProGln: 2.19 ± 0.035	2.834ProArg: 2.834 ± 0.046	2.572ProSer: 2.572 ± 0.04	2.211ProThr: 2.211 ± 0.035	3.881ProVal: 3.881 ± 0.057	0.76ProTrp: 0.76 ± 0.022	1.177ProTyr: 1.177 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	5.769GlnAla: 5.769 ± 0.061	0.326GlnCys: 0.326 ± 0.014	1.906GlnAsp: 1.906 ± 0.029	1.99GlnGlu: 1.99 ± 0.035	1.301GlnPhe: 1.301 ± 0.031	3.56GlnGly: 3.56 ± 0.049	1.04GlnHis: 1.04 ± 0.026	1.681GlnIle: 1.681 ± 0.033	1.112GlnLys: 1.112 ± 0.027	5.317GlnLeu: 5.317 ± 0.067	0.965GlnMet: 0.965 ± 0.025	0.987GlnAsn: 0.987 ± 0.025	2.403GlnPro: 2.403 ± 0.043	2.358GlnGln: 2.358 ± 0.051	3.694GlnArg: 3.694 ± 0.062	2.081GlnSer: 2.081 ± 0.036	1.664GlnThr: 1.664 ± 0.027	3.571GlnVal: 3.571 ± 0.048	0.622GlnTrp: 0.622 ± 0.018	0.928GlnTyr: 0.928 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	6.609ArgAla: 6.609 ± 0.073	0.609ArgCys: 0.609 ± 0.018	3.801ArgAsp: 3.801 ± 0.048	4.717ArgGlu: 4.717 ± 0.064	2.838ArgPhe: 2.838 ± 0.047	4.436ArgGly: 4.436 ± 0.053	1.806ArgHis: 1.806 ± 0.032	3.414ArgIle: 3.414 ± 0.046	2.033ArgLys: 2.033 ± 0.033	9.068ArgLeu: 9.068 ± 0.106	1.655ArgMet: 1.655 ± 0.032	2.002ArgAsn: 2.002 ± 0.038	3.045ArgPro: 3.045 ± 0.042	3.532ArgGln: 3.532 ± 0.053	4.737ArgArg: 4.737 ± 0.063	3.399ArgSer: 3.399 ± 0.052	2.731ArgThr: 2.731 ± 0.045	4.71ArgVal: 4.71 ± 0.058	1.092ArgTrp: 1.092 ± 0.023	2.071ArgTyr: 2.071 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	5.96SerAla: 5.96 ± 0.067	0.483SerCys: 0.483 ± 0.017	2.78SerAsp: 2.78 ± 0.048	2.894SerGlu: 2.894 ± 0.042	2.218SerPhe: 2.218 ± 0.047	5.292SerGly: 5.292 ± 0.075	1.284SerHis: 1.284 ± 0.027	2.56SerIle: 2.56 ± 0.04	1.523SerLys: 1.523 ± 0.029	7.101SerLeu: 7.101 ± 0.081	1.306SerMet: 1.306 ± 0.025	1.559SerAsn: 1.559 ± 0.042	2.66SerPro: 2.66 ± 0.041	2.188SerGln: 2.188 ± 0.037	3.75SerArg: 3.75 ± 0.046	3.089SerSer: 3.089 ± 0.05	2.57SerThr: 2.57 ± 0.045	3.764SerVal: 3.764 ± 0.055	0.82SerTrp: 0.82 ± 0.023	1.443SerTyr: 1.443 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	4.923ThrAla: 4.923 ± 0.072	0.444ThrCys: 0.444 ± 0.017	2.301ThrAsp: 2.301 ± 0.044	2.278ThrGlu: 2.278 ± 0.036	1.696ThrPhe: 1.696 ± 0.038	4.259ThrGly: 4.259 ± 0.08	0.933ThrHis: 0.933 ± 0.02	1.807ThrIle: 1.807 ± 0.051	0.957ThrLys: 0.957 ± 0.026	6.395ThrLeu: 6.395 ± 0.087	0.776ThrMet: 0.776 ± 0.021	1.138ThrAsn: 1.138 ± 0.038	3.022ThrPro: 3.022 ± 0.039	1.808ThrGln: 1.808 ± 0.033	3.084ThrArg: 3.084 ± 0.048	2.528ThrSer: 2.528 ± 0.046	2.315ThrThr: 2.315 ± 0.059	3.213ThrVal: 3.213 ± 0.062	0.706ThrTrp: 0.706 ± 0.018	1.232ThrTyr: 1.232 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	8.107ValAla: 8.107 ± 0.079	0.686ValCys: 0.686 ± 0.018	4.121ValAsp: 4.121 ± 0.049	4.547ValGlu: 4.547 ± 0.049	2.529ValPhe: 2.529 ± 0.039	5.436ValGly: 5.436 ± 0.068	1.375ValHis: 1.375 ± 0.027	3.566ValIle: 3.566 ± 0.046	2.233ValLys: 2.233 ± 0.04	8.29ValLeu: 8.29 ± 0.082	1.643ValMet: 1.643 ± 0.032	2.151ValAsn: 2.151 ± 0.047	3.481ValPro: 3.481 ± 0.043	2.71ValGln: 2.71 ± 0.041	4.577ValArg: 4.577 ± 0.058	4.031ValSer: 4.031 ± 0.049	3.545ValThr: 3.545 ± 0.068	5.488ValVal: 5.488 ± 0.076	0.796ValTrp: 0.796 ± 0.02	1.524ValTyr: 1.524 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.214TrpAla: 1.214 ± 0.032	0.164TrpCys: 0.164 ± 0.009	0.624TrpAsp: 0.624 ± 0.019	0.62TrpGlu: 0.62 ± 0.019	0.565TrpPhe: 0.565 ± 0.017	0.951TrpGly: 0.951 ± 0.023	0.376TrpHis: 0.376 ± 0.014	0.63TrpIle: 0.63 ± 0.019	0.431TrpLys: 0.431 ± 0.013	2.211TrpLeu: 2.211 ± 0.042	0.371TrpMet: 0.371 ± 0.013	0.472TrpAsn: 0.472 ± 0.017	0.664TrpPro: 0.664 ± 0.019	0.89TrpGln: 0.89 ± 0.023	1.181TrpArg: 1.181 ± 0.032	0.821TrpSer: 0.821 ± 0.02	0.658TrpThr: 0.658 ± 0.02	0.946TrpVal: 0.946 ± 0.023	0.224TrpTrp: 0.224 ± 0.011	0.354TrpTyr: 0.354 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.5TyrAla: 2.5 ± 0.043	0.289TyrCys: 0.289 ± 0.013	1.366TyrAsp: 1.366 ± 0.03	1.135TyrGlu: 1.135 ± 0.025	1.011TyrPhe: 1.011 ± 0.026	2.169TyrGly: 2.169 ± 0.038	0.572TyrHis: 0.572 ± 0.018	0.932TyrIle: 0.932 ± 0.023	0.725TyrLys: 0.725 ± 0.021	3.102TyrLeu: 3.102 ± 0.038	0.463TyrMet: 0.463 ± 0.015	0.715TyrAsn: 0.715 ± 0.022	1.315TyrPro: 1.315 ± 0.025	1.242TyrGln: 1.242 ± 0.025	2.077TyrArg: 2.077 ± 0.035	1.542TyrSer: 1.542 ± 0.031	1.148TyrThr: 1.148 ± 0.028	1.583TyrVal: 1.583 ± 0.033	0.414TyrTrp: 0.414 ± 0.017	0.712TyrTyr: 0.712 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5795 proteins (1892167 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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