Amino acid dipepetide frequency for Dragonfly larvae associated circular virus-3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.936AlaAla: 15.936 ± 1.381
1.992AlaCys: 1.992 ± 1.283
5.976AlaAsp: 5.976 ± 0.888
1.992AlaGlu: 1.992 ± 1.283
1.992AlaPhe: 1.992 ± 1.283
5.976AlaGly: 5.976 ± 0.888
0.0AlaHis: 0.0 ± 0.0
3.984AlaIle: 3.984 ± 2.566
5.976AlaLys: 5.976 ± 0.888
7.968AlaLeu: 7.968 ± 3.752
1.992AlaMet: 1.992 ± 1.283
3.984AlaAsn: 3.984 ± 2.566
3.984AlaPro: 3.984 ± 3.357
5.976AlaGln: 5.976 ± 3.85
5.976AlaArg: 5.976 ± 0.888
3.984AlaSer: 3.984 ± 0.395
7.968AlaThr: 7.968 ± 6.714
5.976AlaVal: 5.976 ± 3.85
0.0AlaTrp: 0.0 ± 0.0
1.992AlaTyr: 1.992 ± 1.283
0.0AlaXaa: 0.0 ± 0.0
Cys
1.992CysAla: 1.992 ± 1.283
0.0CysCys: 0.0 ± 0.0
1.992CysAsp: 1.992 ± 1.283
0.0CysGlu: 0.0 ± 0.0
1.992CysPhe: 1.992 ± 1.283
1.992CysGly: 1.992 ± 1.283
1.992CysHis: 1.992 ± 1.283
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.992CysLeu: 1.992 ± 1.283
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
3.984CysGln: 3.984 ± 3.357
0.0CysArg: 0.0 ± 0.0
3.984CysSer: 3.984 ± 0.395
1.992CysThr: 1.992 ± 1.678
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.992AspAla: 1.992 ± 1.283
0.0AspCys: 0.0 ± 0.0
3.984AspAsp: 3.984 ± 2.566
0.0AspGlu: 0.0 ± 0.0
5.976AspPhe: 5.976 ± 5.035
9.96AspGly: 9.96 ± 6.416
3.984AspHis: 3.984 ± 2.566
5.976AspIle: 5.976 ± 0.888
3.984AspLys: 3.984 ± 3.357
3.984AspLeu: 3.984 ± 3.357
3.984AspMet: 3.984 ± 2.566
0.0AspAsn: 0.0 ± 0.0
1.992AspPro: 1.992 ± 1.283
0.0AspGln: 0.0 ± 0.0
1.992AspArg: 1.992 ± 1.283
0.0AspSer: 0.0 ± 0.0
0.0AspThr: 0.0 ± 0.0
9.96AspVal: 9.96 ± 3.454
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.976GluAla: 5.976 ± 3.85
0.0GluCys: 0.0 ± 0.0
1.992GluAsp: 1.992 ± 1.283
1.992GluGlu: 1.992 ± 1.283
0.0GluPhe: 0.0 ± 0.0
0.0GluGly: 0.0 ± 0.0
3.984GluHis: 3.984 ± 2.566
3.984GluIle: 3.984 ± 0.395
3.984GluLys: 3.984 ± 0.395
0.0GluLeu: 0.0 ± 0.0
3.984GluMet: 3.984 ± 3.357
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
1.992GluGln: 1.992 ± 1.283
3.984GluArg: 3.984 ± 2.566
0.0GluSer: 0.0 ± 0.0
3.984GluThr: 3.984 ± 2.566
3.984GluVal: 3.984 ± 2.566
0.0GluTrp: 0.0 ± 0.0
1.992GluTyr: 1.992 ± 1.283
0.0GluXaa: 0.0 ± 0.0
Phe
3.984PheAla: 3.984 ± 3.357
0.0PheCys: 0.0 ± 0.0
1.992PheAsp: 1.992 ± 1.678
1.992PheGlu: 1.992 ± 1.283
0.0PhePhe: 0.0 ± 0.0
3.984PheGly: 3.984 ± 2.566
0.0PheHis: 0.0 ± 0.0
1.992PheIle: 1.992 ± 1.283
3.984PheLys: 3.984 ± 0.395
3.984PheLeu: 3.984 ± 3.357
0.0PheMet: 0.0 ± 0.0
3.984PheAsn: 3.984 ± 2.566
3.984PhePro: 3.984 ± 2.566
1.992PheGln: 1.992 ± 1.678
0.0PheArg: 0.0 ± 0.0
0.0PheSer: 0.0 ± 0.0
1.992PheThr: 1.992 ± 1.283
5.976PheVal: 5.976 ± 0.888
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
15.936GlyAla: 15.936 ± 1.581
1.992GlyCys: 1.992 ± 1.283
3.984GlyAsp: 3.984 ± 2.566
3.984GlyGlu: 3.984 ± 2.566
1.992GlyPhe: 1.992 ± 1.283
1.992GlyGly: 1.992 ± 1.283
1.992GlyHis: 1.992 ± 1.678
3.984GlyIle: 3.984 ± 3.357
3.984GlyLys: 3.984 ± 0.395
5.976GlyLeu: 5.976 ± 0.888
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
1.992GlyPro: 1.992 ± 1.678
1.992GlyGln: 1.992 ± 1.283
5.976GlyArg: 5.976 ± 2.074
7.968GlySer: 7.968 ± 3.752
5.976GlyThr: 5.976 ± 3.85
3.984GlyVal: 3.984 ± 2.566
1.992GlyTrp: 1.992 ± 1.283
1.992GlyTyr: 1.992 ± 1.283
0.0GlyXaa: 0.0 ± 0.0
His
1.992HisAla: 1.992 ± 1.283
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.992HisGlu: 1.992 ± 1.283
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.992HisHis: 1.992 ± 1.283
5.976HisIle: 5.976 ± 5.035
0.0HisLys: 0.0 ± 0.0
5.976HisLeu: 5.976 ± 3.85
1.992HisMet: 1.992 ± 1.283
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.992HisGln: 1.992 ± 1.678
1.992HisArg: 1.992 ± 1.678
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.992HisTyr: 1.992 ± 1.283
0.0HisXaa: 0.0 ± 0.0
Ile
3.984IleAla: 3.984 ± 0.395
0.0IleCys: 0.0 ± 0.0
1.992IleAsp: 1.992 ± 1.678
1.992IleGlu: 1.992 ± 1.283
1.992IlePhe: 1.992 ± 1.283
3.984IleGly: 3.984 ± 0.395
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.992IleLys: 1.992 ± 1.678
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.938
5.976IleAsn: 5.976 ± 5.035
1.992IlePro: 1.992 ± 1.678
0.0IleGln: 0.0 ± 0.0
5.976IleArg: 5.976 ± 3.85
5.976IleSer: 5.976 ± 0.888
1.992IleThr: 1.992 ± 1.678
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.992IleTyr: 1.992 ± 1.283
0.0IleXaa: 0.0 ± 0.0
Lys
3.984LysAla: 3.984 ± 0.395
1.992LysCys: 1.992 ± 1.678
5.976LysAsp: 5.976 ± 3.85
1.992LysGlu: 1.992 ± 1.283
5.976LysPhe: 5.976 ± 2.074
5.976LysGly: 5.976 ± 0.888
1.992LysHis: 1.992 ± 1.678
1.992LysIle: 1.992 ± 1.678
3.984LysLys: 3.984 ± 0.395
0.0LysLeu: 0.0 ± 0.0
1.992LysMet: 1.992 ± 1.283
3.984LysAsn: 3.984 ± 0.395
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
7.968LysArg: 7.968 ± 0.791
3.984LysSer: 3.984 ± 0.395
1.992LysThr: 1.992 ± 1.283
0.0LysVal: 0.0 ± 0.0
1.992LysTrp: 1.992 ± 1.283
1.992LysTyr: 1.992 ± 1.678
0.0LysXaa: 0.0 ± 0.0
Leu
5.976LeuAla: 5.976 ± 0.888
0.0LeuCys: 0.0 ± 0.0
7.968LeuAsp: 7.968 ± 0.791
5.976LeuGlu: 5.976 ± 2.074
1.992LeuPhe: 1.992 ± 1.678
1.992LeuGly: 1.992 ± 1.678
1.992LeuHis: 1.992 ± 1.678
0.0LeuIle: 0.0 ± 0.0
3.984LeuLys: 3.984 ± 2.566
3.984LeuLeu: 3.984 ± 0.395
0.0LeuMet: 0.0 ± 0.0
7.968LeuAsn: 7.968 ± 3.752
3.984LeuPro: 3.984 ± 0.395
1.992LeuGln: 1.992 ± 1.283
5.976LeuArg: 5.976 ± 2.074
1.992LeuSer: 1.992 ± 1.283
1.992LeuThr: 1.992 ± 1.678
1.992LeuVal: 1.992 ± 1.678
1.992LeuTrp: 1.992 ± 1.283
3.984LeuTyr: 3.984 ± 0.395
0.0LeuXaa: 0.0 ± 0.0
Met
3.984MetAla: 3.984 ± 2.566
0.0MetCys: 0.0 ± 0.0
3.984MetAsp: 3.984 ± 2.566
0.0MetGlu: 0.0 ± 0.0
1.992MetPhe: 1.992 ± 1.283
1.992MetGly: 1.992 ± 1.283
0.0MetHis: 0.0 ± 0.0
1.992MetIle: 1.992 ± 1.283
7.968MetLys: 7.968 ± 3.752
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.992MetArg: 1.992 ± 1.678
0.0MetSer: 0.0 ± 0.0
1.992MetThr: 1.992 ± 1.283
5.976MetVal: 5.976 ± 5.035
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
7.968AsnAla: 7.968 ± 0.791
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
7.968AsnGly: 7.968 ± 0.791
0.0AsnHis: 0.0 ± 0.0
3.984AsnIle: 3.984 ± 0.395
1.992AsnLys: 1.992 ± 1.283
5.976AsnLeu: 5.976 ± 5.035
1.992AsnMet: 1.992 ± 1.678
5.976AsnAsn: 5.976 ± 2.074
1.992AsnPro: 1.992 ± 1.283
0.0AsnGln: 0.0 ± 0.0
5.976AsnArg: 5.976 ± 0.888
1.992AsnSer: 1.992 ± 1.678
3.984AsnThr: 3.984 ± 3.357
3.984AsnVal: 3.984 ± 0.395
0.0AsnTrp: 0.0 ± 0.0
1.992AsnTyr: 1.992 ± 1.283
0.0AsnXaa: 0.0 ± 0.0
Pro
3.984ProAla: 3.984 ± 0.395
1.992ProCys: 1.992 ± 1.283
7.968ProAsp: 7.968 ± 2.171
3.984ProGlu: 3.984 ± 2.566
1.992ProPhe: 1.992 ± 1.283
1.992ProGly: 1.992 ± 1.678
1.992ProHis: 1.992 ± 1.283
0.0ProIle: 0.0 ± 0.0
1.992ProLys: 1.992 ± 1.283
1.992ProLeu: 1.992 ± 1.283
0.0ProMet: 0.0 ± 0.0
5.976ProAsn: 5.976 ± 2.074
1.992ProPro: 1.992 ± 1.678
0.0ProGln: 0.0 ± 0.0
3.984ProArg: 3.984 ± 3.357
0.0ProSer: 0.0 ± 0.0
1.992ProThr: 1.992 ± 1.678
1.992ProVal: 1.992 ± 1.678
1.992ProTrp: 1.992 ± 1.678
5.976ProTyr: 5.976 ± 2.074
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.992GlnCys: 1.992 ± 1.678
1.992GlnAsp: 1.992 ± 1.283
1.992GlnGlu: 1.992 ± 1.283
1.992GlnPhe: 1.992 ± 1.283
3.984GlnGly: 3.984 ± 2.566
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.992GlnLys: 1.992 ± 1.678
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
5.976GlnAsn: 5.976 ± 2.074
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
5.976GlnArg: 5.976 ± 2.074
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
1.992GlnVal: 1.992 ± 1.678
0.0GlnTrp: 0.0 ± 0.0
1.992GlnTyr: 1.992 ± 1.283
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
3.984ArgCys: 3.984 ± 3.357
1.992ArgAsp: 1.992 ± 1.283
3.984ArgGlu: 3.984 ± 0.395
5.976ArgPhe: 5.976 ± 0.888
9.96ArgGly: 9.96 ± 2.469
1.992ArgHis: 1.992 ± 1.283
1.992ArgIle: 1.992 ± 1.678
1.992ArgLys: 1.992 ± 1.678
1.992ArgLeu: 1.992 ± 1.283
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
9.96ArgPro: 9.96 ± 0.493
3.984ArgGln: 3.984 ± 3.357
5.976ArgArg: 5.976 ± 3.85
5.976ArgSer: 5.976 ± 0.888
3.984ArgThr: 3.984 ± 0.395
3.984ArgVal: 3.984 ± 3.357
3.984ArgTrp: 3.984 ± 2.566
7.968ArgTyr: 7.968 ± 2.171
0.0ArgXaa: 0.0 ± 0.0
Ser
3.984SerAla: 3.984 ± 2.566
0.0SerCys: 0.0 ± 0.0
1.992SerAsp: 1.992 ± 1.678
1.992SerGlu: 1.992 ± 1.283
0.0SerPhe: 0.0 ± 0.0
1.992SerGly: 1.992 ± 1.283
1.992SerHis: 1.992 ± 1.678
3.984SerIle: 3.984 ± 2.566
3.984SerLys: 3.984 ± 2.566
1.992SerLeu: 1.992 ± 1.678
1.992SerMet: 1.992 ± 1.678
0.0SerAsn: 0.0 ± 0.0
1.992SerPro: 1.992 ± 1.678
1.992SerGln: 1.992 ± 1.283
5.976SerArg: 5.976 ± 0.888
3.984SerSer: 3.984 ± 3.357
1.992SerThr: 1.992 ± 1.678
5.976SerVal: 5.976 ± 2.074
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.0ThrGlu: 0.0 ± 0.0
3.984ThrPhe: 3.984 ± 0.395
7.968ThrGly: 7.968 ± 3.752
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
1.992ThrLys: 1.992 ± 1.283
7.968ThrLeu: 7.968 ± 2.171
3.984ThrMet: 3.984 ± 2.614
5.976ThrAsn: 5.976 ± 2.074
7.968ThrPro: 7.968 ± 0.791
0.0ThrGln: 0.0 ± 0.0
3.984ThrArg: 3.984 ± 3.357
1.992ThrSer: 1.992 ± 1.283
7.968ThrThr: 7.968 ± 6.714
1.992ThrVal: 1.992 ± 1.283
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.976ValAla: 5.976 ± 0.888
1.992ValCys: 1.992 ± 1.283
3.984ValAsp: 3.984 ± 3.357
7.968ValGlu: 7.968 ± 2.171
0.0ValPhe: 0.0 ± 0.0
5.976ValGly: 5.976 ± 2.074
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
1.992ValLys: 1.992 ± 1.283
9.96ValLeu: 9.96 ± 5.431
1.992ValMet: 1.992 ± 1.283
1.992ValAsn: 1.992 ± 1.283
7.968ValPro: 7.968 ± 0.791
0.0ValGln: 0.0 ± 0.0
0.0ValArg: 0.0 ± 0.0
1.992ValSer: 1.992 ± 1.283
1.992ValThr: 1.992 ± 1.283
7.968ValVal: 7.968 ± 2.171
0.0ValTrp: 0.0 ± 0.0
7.968ValTyr: 7.968 ± 3.752
0.0ValXaa: 0.0 ± 0.0
Trp
1.992TrpAla: 1.992 ± 1.283
3.984TrpCys: 3.984 ± 2.566
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.992TrpLys: 1.992 ± 1.283
1.992TrpLeu: 1.992 ± 1.283
0.0TrpMet: 0.0 ± 0.0
1.992TrpAsn: 1.992 ± 1.678
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.992TrpArg: 1.992 ± 1.678
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.984TyrAla: 3.984 ± 0.395
1.992TyrCys: 1.992 ± 1.283
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.992TyrPhe: 1.992 ± 1.283
0.0TyrGly: 0.0 ± 0.0
1.992TyrHis: 1.992 ± 1.678
1.992TyrIle: 1.992 ± 1.283
0.0TyrLys: 0.0 ± 0.0
0.0TyrLeu: 0.0 ± 0.0
5.976TyrMet: 5.976 ± 0.888
1.992TyrAsn: 1.992 ± 1.283
1.992TyrPro: 1.992 ± 1.283
3.984TyrGln: 3.984 ± 0.395
3.984TyrArg: 3.984 ± 2.566
1.992TyrSer: 1.992 ± 1.283
3.984TyrThr: 3.984 ± 0.395
3.984TyrVal: 3.984 ± 3.357
1.992TyrTrp: 1.992 ± 1.678
1.992TyrTyr: 1.992 ± 1.283
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (503 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski