Amino acid dipepetide frequency for Waddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.071AlaAla: 6.071 ± 0.125	0.981AlaCys: 0.981 ± 0.038	3.232AlaAsp: 3.232 ± 0.069	4.706AlaGlu: 4.706 ± 0.087	3.731AlaPhe: 3.731 ± 0.076	4.516AlaGly: 4.516 ± 0.116	1.449AlaHis: 1.449 ± 0.043	5.456AlaIle: 5.456 ± 0.11	4.6AlaLys: 4.6 ± 0.091	8.155AlaLeu: 8.155 ± 0.118	1.768AlaMet: 1.768 ± 0.052	2.425AlaAsn: 2.425 ± 0.064	2.273AlaPro: 2.273 ± 0.061	2.58AlaGln: 2.58 ± 0.072	2.982AlaArg: 2.982 ± 0.071	4.51AlaSer: 4.51 ± 0.085	2.966AlaThr: 2.966 ± 0.097	4.747AlaVal: 4.747 ± 0.096	0.753AlaTrp: 0.753 ± 0.038	2.298AlaTyr: 2.298 ± 0.069	0.0AlaXaa: 0.0 ± 0.0
Cys	0.844CysAla: 0.844 ± 0.037	0.295CysCys: 0.295 ± 0.028	0.653CysAsp: 0.653 ± 0.038	0.697CysGlu: 0.697 ± 0.033	0.705CysPhe: 0.705 ± 0.037	1.036CysGly: 1.036 ± 0.048	0.331CysHis: 0.331 ± 0.025	0.752CysIle: 0.752 ± 0.029	0.603CysLys: 0.603 ± 0.034	1.399CysLeu: 1.399 ± 0.048	0.273CysMet: 0.273 ± 0.023	0.431CysAsn: 0.431 ± 0.03	0.648CysPro: 0.648 ± 0.039	0.484CysGln: 0.484 ± 0.031	0.735CysArg: 0.735 ± 0.038	0.964CysSer: 0.964 ± 0.04	0.571CysThr: 0.571 ± 0.029	0.767CysVal: 0.767 ± 0.036	0.2CysTrp: 0.2 ± 0.015	0.457CysTyr: 0.457 ± 0.03	0.0CysXaa: 0.0 ± 0.0
Asp	3.506AspAla: 3.506 ± 0.085	0.674AspCys: 0.674 ± 0.036	2.299AspAsp: 2.299 ± 0.066	3.672AspGlu: 3.672 ± 0.082	2.594AspPhe: 2.594 ± 0.066	3.089AspGly: 3.089 ± 0.092	1.4AspHis: 1.4 ± 0.052	2.926AspIle: 2.926 ± 0.067	2.955AspLys: 2.955 ± 0.072	5.778AspLeu: 5.778 ± 0.094	0.917AspMet: 0.917 ± 0.042	1.506AspAsn: 1.506 ± 0.052	3.072AspPro: 3.072 ± 0.08	2.396AspGln: 2.396 ± 0.07	2.703AspArg: 2.703 ± 0.061	3.106AspSer: 3.106 ± 0.071	2.046AspThr: 2.046 ± 0.057	2.714AspVal: 2.714 ± 0.069	0.744AspTrp: 0.744 ± 0.033	1.868AspTyr: 1.868 ± 0.062	0.0AspXaa: 0.0 ± 0.0
Glu	5.242GluAla: 5.242 ± 0.099	0.685GluCys: 0.685 ± 0.041	3.273GluAsp: 3.273 ± 0.077	7.089GluGlu: 7.089 ± 0.133	2.624GluPhe: 2.624 ± 0.062	4.632GluGly: 4.632 ± 0.096	1.557GluHis: 1.557 ± 0.049	5.845GluIle: 5.845 ± 0.115	6.938GluLys: 6.938 ± 0.126	6.733GluLeu: 6.733 ± 0.117	2.282GluMet: 2.282 ± 0.061	3.45GluAsn: 3.45 ± 0.082	1.95GluPro: 1.95 ± 0.059	3.02GluGln: 3.02 ± 0.083	3.783GluArg: 3.783 ± 0.092	4.112GluSer: 4.112 ± 0.09	3.816GluThr: 3.816 ± 0.087	4.478GluVal: 4.478 ± 0.086	0.926GluTrp: 0.926 ± 0.047	2.058GluTyr: 2.058 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	3.058PheAla: 3.058 ± 0.073	0.692PheCys: 0.692 ± 0.036	2.591PheAsp: 2.591 ± 0.075	3.023PheGlu: 3.023 ± 0.07	2.856PhePhe: 2.856 ± 0.074	3.081PheGly: 3.081 ± 0.074	1.218PheHis: 1.218 ± 0.044	3.033PheIle: 3.033 ± 0.072	2.478PheLys: 2.478 ± 0.067	5.027PheLeu: 5.027 ± 0.108	1.017PheMet: 1.017 ± 0.044	1.889PheAsn: 1.889 ± 0.052	2.109PhePro: 2.109 ± 0.063	1.816PheGln: 1.816 ± 0.063	2.015PheArg: 2.015 ± 0.065	4.023PheSer: 4.023 ± 0.078	2.216PheThr: 2.216 ± 0.06	2.65PheVal: 2.65 ± 0.071	0.586PheTrp: 0.586 ± 0.035	1.718PheTyr: 1.718 ± 0.061	0.0PheXaa: 0.0 ± 0.0
Gly	4.46GlyAla: 4.46 ± 0.138	0.979GlyCys: 0.979 ± 0.05	2.948GlyAsp: 2.948 ± 0.072	4.082GlyGlu: 4.082 ± 0.085	3.071GlyPhe: 3.071 ± 0.061	4.32GlyGly: 4.32 ± 0.115	1.391GlyHis: 1.391 ± 0.056	5.286GlyIle: 5.286 ± 0.118	5.324GlyLys: 5.324 ± 0.095	5.878GlyLeu: 5.878 ± 0.109	1.933GlyMet: 1.933 ± 0.07	2.67GlyAsn: 2.67 ± 0.093	1.796GlyPro: 1.796 ± 0.11	2.093GlyGln: 2.093 ± 0.058	3.137GlyArg: 3.137 ± 0.077	4.32GlySer: 4.32 ± 0.095	3.181GlyThr: 3.181 ± 0.074	4.449GlyVal: 4.449 ± 0.091	0.934GlyTrp: 0.934 ± 0.04	2.358GlyTyr: 2.358 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	1.537HisAla: 1.537 ± 0.05	0.384HisCys: 0.384 ± 0.027	1.031HisAsp: 1.031 ± 0.034	1.323HisGlu: 1.323 ± 0.044	1.406HisPhe: 1.406 ± 0.044	1.3HisGly: 1.3 ± 0.043	0.767HisHis: 0.767 ± 0.039	1.423HisIle: 1.423 ± 0.053	1.002HisLys: 1.002 ± 0.04	3.093HisLeu: 3.093 ± 0.082	0.398HisMet: 0.398 ± 0.024	0.761HisAsn: 0.761 ± 0.04	1.558HisPro: 1.558 ± 0.052	1.213HisGln: 1.213 ± 0.047	1.259HisArg: 1.259 ± 0.047	1.473HisSer: 1.473 ± 0.051	1.027HisThr: 1.027 ± 0.038	1.274HisVal: 1.274 ± 0.043	0.39HisTrp: 0.39 ± 0.027	1.083HisTyr: 1.083 ± 0.057	0.0HisXaa: 0.0 ± 0.0
Ile	5.667IleAla: 5.667 ± 0.109	0.978IleCys: 0.978 ± 0.043	4.524IleAsp: 4.524 ± 0.09	5.471IleGlu: 5.471 ± 0.095	3.109IlePhe: 3.109 ± 0.077	4.945IleGly: 4.945 ± 0.099	1.796IleHis: 1.796 ± 0.055	3.801IleIle: 3.801 ± 0.077	4.205IleLys: 4.205 ± 0.094	6.709IleLeu: 6.709 ± 0.114	1.168IleMet: 1.168 ± 0.046	2.811IleAsn: 2.811 ± 0.068	3.614IlePro: 3.614 ± 0.097	2.661IleGln: 2.661 ± 0.071	3.402IleArg: 3.402 ± 0.067	5.218IleSer: 5.218 ± 0.095	3.034IleThr: 3.034 ± 0.07	4.128IleVal: 4.128 ± 0.09	0.659IleTrp: 0.659 ± 0.038	2.206IleTyr: 2.206 ± 0.057	0.0IleXaa: 0.0 ± 0.0
Lys	4.612LysAla: 4.612 ± 0.089	0.656LysCys: 0.656 ± 0.032	3.362LysAsp: 3.362 ± 0.083	6.767LysGlu: 6.767 ± 0.139	2.115LysPhe: 2.115 ± 0.054	4.627LysGly: 4.627 ± 0.091	1.452LysHis: 1.452 ± 0.043	5.224LysIle: 5.224 ± 0.089	6.433LysLys: 6.433 ± 0.123	5.784LysLeu: 5.784 ± 0.088	1.786LysMet: 1.786 ± 0.055	3.257LysAsn: 3.257 ± 0.083	2.389LysPro: 2.389 ± 0.062	3.034LysGln: 3.034 ± 0.071	3.743LysArg: 3.743 ± 0.077	3.837LysSer: 3.837 ± 0.074	3.819LysThr: 3.819 ± 0.083	3.894LysVal: 3.894 ± 0.089	0.811LysTrp: 0.811 ± 0.031	1.869LysTyr: 1.869 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	7.283LeuAla: 7.283 ± 0.126	1.344LeuCys: 1.344 ± 0.054	5.242LeuAsp: 5.242 ± 0.085	7.768LeuGlu: 7.768 ± 0.143	5.181LeuPhe: 5.181 ± 0.107	6.421LeuGly: 6.421 ± 0.131	2.343LeuHis: 2.343 ± 0.067	7.247LeuIle: 7.247 ± 0.118	7.675LeuLys: 7.675 ± 0.14	10.252LeuLeu: 10.252 ± 0.166	2.503LeuMet: 2.503 ± 0.07	4.37LeuAsn: 4.37 ± 0.084	4.667LeuPro: 4.667 ± 0.093	3.973LeuGln: 3.973 ± 0.096	4.761LeuArg: 4.761 ± 0.095	8.135LeuSer: 8.135 ± 0.121	5.262LeuThr: 5.262 ± 0.102	5.219LeuVal: 5.219 ± 0.102	0.981LeuTrp: 0.981 ± 0.041	3.001LeuTyr: 3.001 ± 0.072	0.0LeuXaa: 0.0 ± 0.0
Met	1.839MetAla: 1.839 ± 0.056	0.205MetCys: 0.205 ± 0.019	1.186MetAsp: 1.186 ± 0.043	1.71MetGlu: 1.71 ± 0.056	0.802MetPhe: 0.802 ± 0.04	1.658MetGly: 1.658 ± 0.052	0.512MetHis: 0.512 ± 0.029	1.977MetIle: 1.977 ± 0.051	1.85MetLys: 1.85 ± 0.052	2.162MetLeu: 2.162 ± 0.061	0.691MetMet: 0.691 ± 0.035	1.109MetAsn: 1.109 ± 0.041	0.972MetPro: 0.972 ± 0.041	0.995MetGln: 0.995 ± 0.038	1.326MetArg: 1.326 ± 0.045	1.426MetSer: 1.426 ± 0.044	1.443MetThr: 1.443 ± 0.054	1.402MetVal: 1.402 ± 0.05	0.191MetTrp: 0.191 ± 0.015	0.46MetTyr: 0.46 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	2.896AsnAla: 2.896 ± 0.067	0.56AsnCys: 0.56 ± 0.032	1.809AsnAsp: 1.809 ± 0.058	2.507AsnGlu: 2.507 ± 0.08	1.8AsnPhe: 1.8 ± 0.054	2.756AsnGly: 2.756 ± 0.073	1.148AsnHis: 1.148 ± 0.043	2.624AsnIle: 2.624 ± 0.067	2.062AsnLys: 2.062 ± 0.061	4.451AsnLeu: 4.451 ± 0.086	0.703AsnMet: 0.703 ± 0.034	1.359AsnAsn: 1.359 ± 0.051	2.437AsnPro: 2.437 ± 0.06	1.875AsnGln: 1.875 ± 0.057	2.275AsnArg: 2.275 ± 0.063	2.326AsnSer: 2.326 ± 0.062	1.812AsnThr: 1.812 ± 0.052	2.273AsnVal: 2.273 ± 0.058	0.544AsnTrp: 0.544 ± 0.031	1.32AsnTyr: 1.32 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	2.453ProAla: 2.453 ± 0.065	0.446ProCys: 0.446 ± 0.029	2.355ProAsp: 2.355 ± 0.065	3.765ProGlu: 3.765 ± 0.083	2.251ProPhe: 2.251 ± 0.066	2.506ProGly: 2.506 ± 0.072	0.998ProHis: 0.998 ± 0.036	2.832ProIle: 2.832 ± 0.068	2.767ProLys: 2.767 ± 0.07	4.389ProLeu: 4.389 ± 0.094	0.879ProMet: 0.879 ± 0.039	1.752ProAsn: 1.752 ± 0.048	1.73ProPro: 1.73 ± 0.065	1.519ProGln: 1.519 ± 0.056	1.613ProArg: 1.613 ± 0.054	2.999ProSer: 2.999 ± 0.064	1.885ProThr: 1.885 ± 0.075	2.723ProVal: 2.723 ± 0.067	0.518ProTrp: 0.518 ± 0.029	1.491ProTyr: 1.491 ± 0.052	0.0ProXaa: 0.0 ± 0.0
Gln	3.101GlnAla: 3.101 ± 0.085	0.395GlnCys: 0.395 ± 0.029	1.563GlnAsp: 1.563 ± 0.058	3.362GlnGlu: 3.362 ± 0.083	1.698GlnPhe: 1.698 ± 0.047	2.355GlnGly: 2.355 ± 0.058	0.879GlnHis: 0.879 ± 0.039	2.853GlnIle: 2.853 ± 0.086	3.242GlnLys: 3.242 ± 0.074	4.386GlnLeu: 4.386 ± 0.099	1.087GlnMet: 1.087 ± 0.04	1.555GlnAsn: 1.555 ± 0.052	1.332GlnPro: 1.332 ± 0.044	1.739GlnGln: 1.739 ± 0.063	1.857GlnArg: 1.857 ± 0.062	2.421GlnSer: 2.421 ± 0.073	2.197GlnThr: 2.197 ± 0.063	2.36GlnVal: 2.36 ± 0.07	0.594GlnTrp: 0.594 ± 0.035	1.254GlnTyr: 1.254 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	2.811ArgAla: 2.811 ± 0.065	0.688ArgCys: 0.688 ± 0.038	2.292ArgAsp: 2.292 ± 0.062	3.799ArgGlu: 3.799 ± 0.085	2.449ArgPhe: 2.449 ± 0.061	2.644ArgGly: 2.644 ± 0.061	1.145ArgHis: 1.145 ± 0.043	3.594ArgIle: 3.594 ± 0.075	3.714ArgLys: 3.714 ± 0.087	5.361ArgLeu: 5.361 ± 0.101	1.352ArgMet: 1.352 ± 0.045	2.014ArgAsn: 2.014 ± 0.053	1.645ArgPro: 1.645 ± 0.06	2.17ArgGln: 2.17 ± 0.061	2.509ArgArg: 2.509 ± 0.081	3.26ArgSer: 3.26 ± 0.064	2.076ArgThr: 2.076 ± 0.061	2.897ArgVal: 2.897 ± 0.064	0.626ArgTrp: 0.626 ± 0.034	1.927ArgTyr: 1.927 ± 0.06	0.0ArgXaa: 0.0 ± 0.0
Ser	4.284SerAla: 4.284 ± 0.085	0.89SerCys: 0.89 ± 0.036	3.444SerAsp: 3.444 ± 0.074	4.574SerGlu: 4.574 ± 0.092	3.379SerPhe: 3.379 ± 0.075	4.553SerGly: 4.553 ± 0.093	1.573SerHis: 1.573 ± 0.052	4.63SerIle: 4.63 ± 0.094	4.231SerLys: 4.231 ± 0.092	7.664SerLeu: 7.664 ± 0.123	1.705SerMet: 1.705 ± 0.054	2.333SerAsn: 2.333 ± 0.06	2.891SerPro: 2.891 ± 0.075	2.654SerGln: 2.654 ± 0.073	3.307SerArg: 3.307 ± 0.075	5.089SerSer: 5.089 ± 0.104	3.159SerThr: 3.159 ± 0.071	3.824SerVal: 3.824 ± 0.077	0.905SerTrp: 0.905 ± 0.035	2.331SerTyr: 2.331 ± 0.071	0.0SerXaa: 0.0 ± 0.0
Thr	3.622ThrAla: 3.622 ± 0.085	0.569ThrCys: 0.569 ± 0.034	2.216ThrAsp: 2.216 ± 0.054	2.843ThrGlu: 2.843 ± 0.075	2.305ThrPhe: 2.305 ± 0.056	3.566ThrGly: 3.566 ± 0.138	1.203ThrHis: 1.203 ± 0.044	3.481ThrIle: 3.481 ± 0.079	2.632ThrLys: 2.632 ± 0.071	5.462ThrLeu: 5.462 ± 0.096	0.983ThrMet: 0.983 ± 0.041	1.534ThrAsn: 1.534 ± 0.049	2.589ThrPro: 2.589 ± 0.067	1.722ThrGln: 1.722 ± 0.056	2.12ThrArg: 2.12 ± 0.056	3.104ThrSer: 3.104 ± 0.069	2.337ThrThr: 2.337 ± 0.064	3.259ThrVal: 3.259 ± 0.082	0.506ThrTrp: 0.506 ± 0.032	1.672ThrTyr: 1.672 ± 0.093	0.0ThrXaa: 0.0 ± 0.0
Val	4.102ValAla: 4.102 ± 0.084	0.855ValCys: 0.855 ± 0.04	3.405ValAsp: 3.405 ± 0.07	4.377ValGlu: 4.377 ± 0.093	2.812ValPhe: 2.812 ± 0.072	3.793ValGly: 3.793 ± 0.113	1.349ValHis: 1.349 ± 0.05	4.5ValIle: 4.5 ± 0.093	4.073ValLys: 4.073 ± 0.079	5.661ValLeu: 5.661 ± 0.112	1.453ValMet: 1.453 ± 0.048	2.542ValAsn: 2.542 ± 0.072	2.442ValPro: 2.442 ± 0.067	2.112ValGln: 2.112 ± 0.058	2.765ValArg: 2.765 ± 0.078	4.238ValSer: 4.238 ± 0.095	2.623ValThr: 2.623 ± 0.071	4.038ValVal: 4.038 ± 0.093	0.635ValTrp: 0.635 ± 0.039	1.724ValTyr: 1.724 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	0.635TrpAla: 0.635 ± 0.037	0.117TrpCys: 0.117 ± 0.015	0.595TrpAsp: 0.595 ± 0.029	0.896TrpGlu: 0.896 ± 0.034	0.504TrpPhe: 0.504 ± 0.025	0.847TrpGly: 0.847 ± 0.038	0.279TrpHis: 0.279 ± 0.024	1.001TrpIle: 1.001 ± 0.041	1.092TrpLys: 1.092 ± 0.047	1.27TrpLeu: 1.27 ± 0.047	0.415TrpMet: 0.415 ± 0.027	0.655TrpAsn: 0.655 ± 0.03	0.314TrpPro: 0.314 ± 0.022	0.515TrpGln: 0.515 ± 0.028	0.573TrpArg: 0.573 ± 0.028	0.641TrpSer: 0.641 ± 0.037	0.524TrpThr: 0.524 ± 0.029	0.723TrpVal: 0.723 ± 0.035	0.217TrpTrp: 0.217 ± 0.024	0.345TrpTyr: 0.345 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.176TyrAla: 2.176 ± 0.066	0.451TyrCys: 0.451 ± 0.027	1.948TyrAsp: 1.948 ± 0.137	2.064TyrGlu: 2.064 ± 0.055	1.707TyrPhe: 1.707 ± 0.05	1.968TyrGly: 1.968 ± 0.058	0.913TyrHis: 0.913 ± 0.037	1.62TyrIle: 1.62 ± 0.047	1.596TyrLys: 1.596 ± 0.047	4.012TyrLeu: 4.012 ± 0.091	0.6TyrMet: 0.6 ± 0.029	1.115TyrAsn: 1.115 ± 0.056	1.44TyrPro: 1.44 ± 0.049	1.658TyrGln: 1.658 ± 0.059	2.108TyrArg: 2.108 ± 0.056	2.217TyrSer: 2.217 ± 0.057	1.731TyrThr: 1.731 ± 0.074	1.68TyrVal: 1.68 ± 0.042	0.436TyrTrp: 0.436 ± 0.024	1.118TyrTyr: 1.118 ± 0.051	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1919 proteins (658510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---