Amino acid dipepetide frequency for Blackberry virus F

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.291AlaAla: 5.291 ± 4.173
0.441AlaCys: 0.441 ± 0.2
0.882AlaAsp: 0.882 ± 0.4
6.614AlaGlu: 6.614 ± 1.36
0.882AlaPhe: 0.882 ± 0.4
3.086AlaGly: 3.086 ± 1.136
1.323AlaHis: 1.323 ± 0.6
3.968AlaIle: 3.968 ± 0.932
4.409AlaLys: 4.409 ± 5.868
4.409AlaLeu: 4.409 ± 5.086
2.205AlaMet: 2.205 ± 1.0
1.323AlaAsn: 1.323 ± 0.6
2.205AlaPro: 2.205 ± 1.0
3.086AlaGln: 3.086 ± 0.845
3.086AlaArg: 3.086 ± 1.465
4.85AlaSer: 4.85 ± 2.201
3.968AlaThr: 3.968 ± 2.848
5.732AlaVal: 5.732 ± 2.601
1.323AlaTrp: 1.323 ± 0.6
1.764AlaTyr: 1.764 ± 0.8
0.0AlaXaa: 0.0 ± 0.0
Cys
0.882CysAla: 0.882 ± 0.4
0.441CysCys: 0.441 ± 0.2
0.882CysAsp: 0.882 ± 0.4
1.323CysGlu: 1.323 ± 0.6
1.323CysPhe: 1.323 ± 1.168
0.882CysGly: 0.882 ± 0.4
0.441CysHis: 0.441 ± 0.2
0.441CysIle: 0.441 ± 0.2
3.527CysLys: 3.527 ± 0.867
0.441CysLeu: 0.441 ± 0.2
0.441CysMet: 0.441 ± 0.2
0.441CysAsn: 0.441 ± 0.2
0.882CysPro: 0.882 ± 0.4
0.882CysGln: 0.882 ± 0.4
0.441CysArg: 0.441 ± 0.2
1.323CysSer: 1.323 ± 0.6
0.0CysThr: 0.0 ± 0.0
0.441CysVal: 0.441 ± 0.2
0.0CysTrp: 0.0 ± 0.0
0.882CysTyr: 0.882 ± 0.4
0.0CysXaa: 0.0 ± 0.0
Asp
1.323AspAla: 1.323 ± 0.6
0.441AspCys: 0.441 ± 0.2
4.85AspAsp: 4.85 ± 1.159
4.409AspGlu: 4.409 ± 2.001
2.205AspPhe: 2.205 ± 1.214
2.646AspGly: 2.646 ± 1.2
0.441AspHis: 0.441 ± 0.2
2.646AspIle: 2.646 ± 1.2
2.646AspLys: 2.646 ± 1.661
6.614AspLeu: 6.614 ± 5.596
1.323AspMet: 1.323 ± 0.6
2.646AspAsn: 2.646 ± 1.2
3.086AspPro: 3.086 ± 1.136
3.086AspGln: 3.086 ± 1.136
1.323AspArg: 1.323 ± 0.6
1.764AspSer: 1.764 ± 0.8
2.205AspThr: 2.205 ± 1.0
3.086AspVal: 3.086 ± 0.845
1.764AspTrp: 1.764 ± 2.057
3.086AspTyr: 3.086 ± 0.845
0.0AspXaa: 0.0 ± 0.0
Glu
6.614GluAla: 6.614 ± 1.36
0.882GluCys: 0.882 ± 0.4
7.055GluAsp: 7.055 ± 3.575
10.141GluGlu: 10.141 ± 3.304
2.646GluPhe: 2.646 ± 1.661
6.614GluGly: 6.614 ± 0.334
1.764GluHis: 1.764 ± 0.8
4.85GluIle: 4.85 ± 0.699
8.377GluLys: 8.377 ± 2.63
5.291GluLeu: 5.291 ± 1.304
0.882GluMet: 0.882 ± 0.4
2.205GluAsn: 2.205 ± 1.0
2.205GluPro: 2.205 ± 1.0
4.409GluGln: 4.409 ± 4.958
7.496GluArg: 7.496 ± 1.008
6.614GluSer: 6.614 ± 1.906
3.527GluThr: 3.527 ± 1.601
6.173GluVal: 6.173 ± 2.905
0.441GluTrp: 0.441 ± 0.2
1.764GluTyr: 1.764 ± 0.8
0.0GluXaa: 0.0 ± 0.0
Phe
2.205PheAla: 2.205 ± 4.734
0.882PheCys: 0.882 ± 1.314
0.882PheAsp: 0.882 ± 0.4
1.323PheGlu: 1.323 ± 1.406
0.441PhePhe: 0.441 ± 1.473
0.441PheGly: 0.441 ± 0.2
1.323PheHis: 1.323 ± 2.785
3.527PheIle: 3.527 ± 1.601
3.086PheLys: 3.086 ± 1.4
1.764PheLeu: 1.764 ± 0.8
0.0PheMet: 0.0 ± 0.0
0.882PheAsn: 0.882 ± 0.4
1.764PhePro: 1.764 ± 0.8
2.205PheGln: 2.205 ± 0.938
2.205PheArg: 2.205 ± 1.0
1.764PheSer: 1.764 ± 0.8
2.205PheThr: 2.205 ± 0.938
0.882PheVal: 0.882 ± 0.4
0.0PheTrp: 0.0 ± 0.0
1.764PheTyr: 1.764 ± 0.8
0.0PheXaa: 0.0 ± 0.0
Gly
3.968GlyAla: 3.968 ± 1.195
1.323GlyCys: 1.323 ± 0.6
1.323GlyAsp: 1.323 ± 0.6
5.732GlyGlu: 5.732 ± 1.703
2.205GlyPhe: 2.205 ± 1.859
1.764GlyGly: 1.764 ± 0.8
0.882GlyHis: 0.882 ± 0.4
3.968GlyIle: 3.968 ± 1.195
4.85GlyLys: 4.85 ± 2.201
6.173GlyLeu: 6.173 ± 2.044
0.882GlyMet: 0.882 ± 0.4
2.205GlyAsn: 2.205 ± 1.0
1.323GlyPro: 1.323 ± 0.6
1.764GlyGln: 1.764 ± 0.8
2.646GlyArg: 2.646 ± 1.2
2.646GlySer: 2.646 ± 1.158
6.173GlyThr: 6.173 ± 2.272
2.646GlyVal: 2.646 ± 1.158
2.205GlyTrp: 2.205 ± 1.0
2.205GlyTyr: 2.205 ± 1.0
0.0GlyXaa: 0.0 ± 0.0
His
1.764HisAla: 1.764 ± 0.8
1.323HisCys: 1.323 ± 0.6
1.323HisAsp: 1.323 ± 0.6
0.441HisGlu: 0.441 ± 0.2
0.882HisPhe: 0.882 ± 0.4
1.764HisGly: 1.764 ± 0.8
0.0HisHis: 0.0 ± 0.0
2.205HisIle: 2.205 ± 1.0
0.882HisLys: 0.882 ± 0.4
2.205HisLeu: 2.205 ± 0.938
0.441HisMet: 0.441 ± 0.2
0.0HisAsn: 0.0 ± 0.0
0.441HisPro: 0.441 ± 0.2
1.764HisGln: 1.764 ± 1.04
1.323HisArg: 1.323 ± 1.168
1.764HisSer: 1.764 ± 4.257
1.323HisThr: 1.323 ± 0.6
1.323HisVal: 1.323 ± 0.6
0.882HisTrp: 0.882 ± 0.4
0.441HisTyr: 0.441 ± 0.2
0.0HisXaa: 0.0 ± 0.0
Ile
3.086IleAla: 3.086 ± 2.203
1.764IleCys: 1.764 ± 0.8
3.086IleAsp: 3.086 ± 1.4
3.086IleGlu: 3.086 ± 0.845
1.323IlePhe: 1.323 ± 1.406
3.086IleGly: 3.086 ± 1.136
1.323IleHis: 1.323 ± 0.6
3.527IleIle: 3.527 ± 2.596
4.409IleLys: 4.409 ± 3.718
2.646IleLeu: 2.646 ± 1.2
1.323IleMet: 1.323 ± 0.553
2.646IleAsn: 2.646 ± 1.2
4.409IlePro: 4.409 ± 2.001
3.968IleGln: 3.968 ± 1.076
3.968IleArg: 3.968 ± 1.801
3.086IleSer: 3.086 ± 0.845
3.527IleThr: 3.527 ± 1.601
1.764IleVal: 1.764 ± 0.8
1.323IleTrp: 1.323 ± 0.6
2.205IleTyr: 2.205 ± 1.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.732LysAla: 5.732 ± 4.017
1.764LysCys: 1.764 ± 0.8
4.85LysAsp: 4.85 ± 3.241
6.614LysGlu: 6.614 ± 1.906
2.205LysPhe: 2.205 ± 1.0
4.409LysGly: 4.409 ± 2.001
3.086LysHis: 3.086 ± 0.845
4.409LysIle: 4.409 ± 0.885
5.291LysLys: 5.291 ± 3.323
5.732LysLeu: 5.732 ± 2.192
2.205LysMet: 2.205 ± 0.929
3.527LysAsn: 3.527 ± 1.601
3.968LysPro: 3.968 ± 1.801
3.086LysGln: 3.086 ± 1.465
3.086LysArg: 3.086 ± 1.136
6.614LysSer: 6.614 ± 1.804
5.291LysThr: 5.291 ± 2.347
3.968LysVal: 3.968 ± 2.848
0.441LysTrp: 0.441 ± 0.2
3.527LysTyr: 3.527 ± 2.08
0.0LysXaa: 0.0 ± 0.0
Leu
6.173LeuAla: 6.173 ± 1.63
0.882LeuCys: 0.882 ± 0.4
3.968LeuAsp: 3.968 ± 2.848
10.582LeuGlu: 10.582 ± 7.076
0.441LeuPhe: 0.441 ± 0.2
7.055LeuGly: 7.055 ± 2.539
0.441LeuHis: 0.441 ± 0.2
2.205LeuIle: 2.205 ± 1.0
6.614LeuLys: 6.614 ± 2.996
5.291LeuLeu: 5.291 ± 3.538
1.764LeuMet: 1.764 ± 0.8
3.527LeuAsn: 3.527 ± 5.257
2.646LeuPro: 2.646 ± 1.2
4.85LeuGln: 4.85 ± 3.995
3.968LeuArg: 3.968 ± 0.932
6.173LeuSer: 6.173 ± 4.812
3.968LeuThr: 3.968 ± 2.505
5.291LeuVal: 5.291 ± 3.538
0.0LeuTrp: 0.0 ± 0.0
2.205LeuTyr: 2.205 ± 1.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.764MetAla: 1.764 ± 0.8
0.882MetCys: 0.882 ± 0.4
1.323MetAsp: 1.323 ± 0.6
3.086MetGlu: 3.086 ± 1.4
0.0MetPhe: 0.0 ± 0.0
0.882MetGly: 0.882 ± 0.4
0.0MetHis: 0.0 ± 0.0
0.882MetIle: 0.882 ± 0.4
3.086MetLys: 3.086 ± 1.4
1.764MetLeu: 1.764 ± 0.8
1.323MetMet: 1.323 ± 0.6
0.441MetAsn: 0.441 ± 0.2
0.882MetPro: 0.882 ± 0.4
0.0MetGln: 0.0 ± 0.0
1.323MetArg: 1.323 ± 0.6
2.646MetSer: 2.646 ± 1.158
1.323MetThr: 1.323 ± 1.168
2.205MetVal: 2.205 ± 1.0
0.0MetTrp: 0.0 ± 0.0
0.441MetTyr: 0.441 ± 0.2
0.0MetXaa: 0.0 ± 0.0
Asn
0.441AsnAla: 0.441 ± 0.2
1.323AsnCys: 1.323 ± 1.168
0.882AsnAsp: 0.882 ± 0.4
3.527AsnGlu: 3.527 ± 0.867
0.882AsnPhe: 0.882 ± 0.4
1.323AsnGly: 1.323 ± 0.6
0.0AsnHis: 0.0 ± 0.0
2.646AsnIle: 2.646 ± 1.2
2.646AsnLys: 2.646 ± 1.2
4.409AsnLeu: 4.409 ± 5.532
0.882AsnMet: 0.882 ± 0.4
0.441AsnAsn: 0.441 ± 0.2
1.323AsnPro: 1.323 ± 0.6
3.086AsnGln: 3.086 ± 0.845
1.323AsnArg: 1.323 ± 0.6
1.323AsnSer: 1.323 ± 1.406
3.527AsnThr: 3.527 ± 1.601
2.646AsnVal: 2.646 ± 1.2
0.882AsnTrp: 0.882 ± 0.4
1.764AsnTyr: 1.764 ± 0.8
0.0AsnXaa: 0.0 ± 0.0
Pro
4.85ProAla: 4.85 ± 2.364
0.441ProCys: 0.441 ± 0.2
3.968ProAsp: 3.968 ± 1.801
4.409ProGlu: 4.409 ± 2.001
1.323ProPhe: 1.323 ± 0.6
2.205ProGly: 2.205 ± 1.0
1.764ProHis: 1.764 ± 0.8
2.646ProIle: 2.646 ± 1.2
3.527ProLys: 3.527 ± 1.269
1.764ProLeu: 1.764 ± 1.04
2.205ProMet: 2.205 ± 1.0
0.441ProAsn: 0.441 ± 0.2
2.646ProPro: 2.646 ± 1.2
2.646ProGln: 2.646 ± 0.87
3.968ProArg: 3.968 ± 1.801
4.409ProSer: 4.409 ± 1.033
2.205ProThr: 2.205 ± 1.0
0.0ProVal: 0.0 ± 0.0
0.882ProTrp: 0.882 ± 0.4
2.205ProTyr: 2.205 ± 1.214
0.0ProXaa: 0.0 ± 0.0
Gln
4.409GlnAla: 4.409 ± 1.271
0.441GlnCys: 0.441 ± 0.2
1.323GlnAsp: 1.323 ± 1.168
4.85GlnGlu: 4.85 ± 2.116
0.882GlnPhe: 0.882 ± 0.4
4.85GlnGly: 4.85 ± 2.364
3.086GlnHis: 3.086 ± 2.203
3.527GlnIle: 3.527 ± 2.596
3.086GlnLys: 3.086 ± 2.203
5.291GlnLeu: 5.291 ± 6.805
0.441GlnMet: 0.441 ± 0.2
4.409GlnAsn: 4.409 ± 2.31
3.968GlnPro: 3.968 ± 2.505
4.409GlnGln: 4.409 ± 3.718
2.646GlnArg: 2.646 ± 1.2
0.882GlnSer: 0.882 ± 1.314
0.441GlnThr: 0.441 ± 0.2
2.646GlnVal: 2.646 ± 1.2
0.882GlnTrp: 0.882 ± 0.4
1.764GlnTyr: 1.764 ± 0.8
0.0GlnXaa: 0.0 ± 0.0
Arg
1.323ArgAla: 1.323 ± 0.6
0.882ArgCys: 0.882 ± 0.4
2.646ArgAsp: 2.646 ± 1.2
3.527ArgGlu: 3.527 ± 1.148
2.205ArgPhe: 2.205 ± 1.0
2.646ArgGly: 2.646 ± 1.158
2.205ArgHis: 2.205 ± 1.0
3.968ArgIle: 3.968 ± 1.97
4.409ArgLys: 4.409 ± 2.001
5.291ArgLeu: 5.291 ± 1.74
1.764ArgMet: 1.764 ± 0.8
0.441ArgAsn: 0.441 ± 0.2
2.646ArgPro: 2.646 ± 0.87
1.764ArgGln: 1.764 ± 0.8
4.409ArgArg: 4.409 ± 1.033
3.968ArgSer: 3.968 ± 1.801
4.85ArgThr: 4.85 ± 0.699
3.968ArgVal: 3.968 ± 1.076
2.646ArgTrp: 2.646 ± 1.2
1.764ArgTyr: 1.764 ± 0.8
0.0ArgXaa: 0.0 ± 0.0
Ser
1.764SerAla: 1.764 ± 1.04
0.441SerCys: 0.441 ± 0.2
4.409SerAsp: 4.409 ± 1.271
4.85SerGlu: 4.85 ± 1.373
3.968SerPhe: 3.968 ± 0.932
4.85SerGly: 4.85 ± 2.201
0.882SerHis: 0.882 ± 0.4
2.646SerIle: 2.646 ± 2.336
4.409SerLys: 4.409 ± 1.271
6.173SerLeu: 6.173 ± 4.287
1.764SerMet: 1.764 ± 0.765
2.205SerAsn: 2.205 ± 0.938
3.086SerPro: 3.086 ± 1.4
3.968SerGln: 3.968 ± 1.076
5.732SerArg: 5.732 ± 1.703
10.141SerSer: 10.141 ± 8.157
4.409SerThr: 4.409 ± 2.001
3.527SerVal: 3.527 ± 1.148
0.882SerTrp: 0.882 ± 0.4
2.646SerTyr: 2.646 ± 1.2
0.0SerXaa: 0.0 ± 0.0
Thr
3.968ThrAla: 3.968 ± 0.932
0.882ThrCys: 0.882 ± 0.4
2.646ThrAsp: 2.646 ± 3.093
7.055ThrGlu: 7.055 ± 2.104
2.205ThrPhe: 2.205 ± 1.0
3.527ThrGly: 3.527 ± 1.148
0.882ThrHis: 0.882 ± 1.314
2.205ThrIle: 2.205 ± 1.0
2.646ThrLys: 2.646 ± 1.158
4.85ThrLeu: 4.85 ± 1.373
1.764ThrMet: 1.764 ± 0.8
2.205ThrAsn: 2.205 ± 1.214
3.086ThrPro: 3.086 ± 1.136
3.527ThrGln: 3.527 ± 4.113
3.086ThrArg: 3.086 ± 1.4
5.732ThrSer: 5.732 ± 2.601
3.086ThrThr: 3.086 ± 1.4
2.205ThrVal: 2.205 ± 0.938
0.441ThrTrp: 0.441 ± 0.2
2.646ThrTyr: 2.646 ± 1.2
0.0ThrXaa: 0.0 ± 0.0
Val
1.764ValAla: 1.764 ± 1.04
0.441ValCys: 0.441 ± 0.2
2.205ValAsp: 2.205 ± 1.0
4.85ValGlu: 4.85 ± 0.699
1.764ValPhe: 1.764 ± 0.8
2.205ValGly: 2.205 ± 0.938
1.764ValHis: 1.764 ± 0.8
3.527ValIle: 3.527 ± 1.601
6.173ValLys: 6.173 ± 4.287
3.527ValLeu: 3.527 ± 1.601
0.882ValMet: 0.882 ± 0.4
1.323ValAsn: 1.323 ± 0.6
3.968ValPro: 3.968 ± 1.076
2.646ValGln: 2.646 ± 3.943
3.086ValArg: 3.086 ± 1.4
1.764ValSer: 1.764 ± 1.298
4.85ValThr: 4.85 ± 1.373
3.968ValVal: 3.968 ± 1.195
0.0ValTrp: 0.0 ± 0.0
3.086ValTyr: 3.086 ± 1.136
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.323TrpAsp: 1.323 ± 1.168
1.323TrpGlu: 1.323 ± 0.6
0.0TrpPhe: 0.0 ± 0.0
0.882TrpGly: 0.882 ± 0.4
0.441TrpHis: 0.441 ± 0.2
0.0TrpIle: 0.0 ± 0.0
1.764TrpLys: 1.764 ± 0.8
1.323TrpLeu: 1.323 ± 0.6
0.441TrpMet: 0.441 ± 0.2
1.323TrpAsn: 1.323 ± 0.6
1.323TrpPro: 1.323 ± 0.6
0.882TrpGln: 0.882 ± 0.4
1.323TrpArg: 1.323 ± 1.406
2.205TrpSer: 2.205 ± 1.0
0.441TrpThr: 0.441 ± 0.2
0.0TrpVal: 0.0 ± 0.0
0.882TrpTrp: 0.882 ± 0.4
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.527TyrAla: 3.527 ± 1.601
0.441TyrCys: 0.441 ± 0.2
1.764TyrAsp: 1.764 ± 0.8
2.205TyrGlu: 2.205 ± 1.0
1.764TyrPhe: 1.764 ± 1.04
1.764TyrGly: 1.764 ± 0.8
0.441TyrHis: 0.441 ± 0.2
1.764TyrIle: 1.764 ± 0.8
3.968TyrLys: 3.968 ± 1.076
3.086TyrLeu: 3.086 ± 0.845
0.882TyrMet: 0.882 ± 0.4
2.646TyrAsn: 2.646 ± 1.2
2.646TyrPro: 2.646 ± 1.2
2.205TyrGln: 2.205 ± 1.0
0.882TyrArg: 0.882 ± 0.4
3.527TyrSer: 3.527 ± 1.601
1.323TyrThr: 1.323 ± 0.6
1.323TyrVal: 1.323 ± 1.406
0.0TyrTrp: 0.0 ± 0.0
2.205TyrTyr: 2.205 ± 1.214
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2269 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski