Amino acid dipepetide frequency for Marinomonas hwangdonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.037AlaAla: 8.037 ± 0.125	0.976AlaCys: 0.976 ± 0.029	4.82AlaAsp: 4.82 ± 0.078	5.362AlaGlu: 5.362 ± 0.081	3.896AlaPhe: 3.896 ± 0.061	6.146AlaGly: 6.146 ± 0.106	1.828AlaHis: 1.828 ± 0.044	6.093AlaIle: 6.093 ± 0.089	4.789AlaLys: 4.789 ± 0.072	10.478AlaLeu: 10.478 ± 0.12	2.693AlaMet: 2.693 ± 0.053	3.589AlaAsn: 3.589 ± 0.06	3.077AlaPro: 3.077 ± 0.066	3.986AlaGln: 3.986 ± 0.073	3.898AlaArg: 3.898 ± 0.075	5.88AlaSer: 5.88 ± 0.083	4.55AlaThr: 4.55 ± 0.086	6.061AlaVal: 6.061 ± 0.076	1.062AlaTrp: 1.062 ± 0.037	2.381AlaTyr: 2.381 ± 0.049	0.002AlaXaa: 0.002 ± 0.001
Cys	0.794CysAla: 0.794 ± 0.024	0.142CysCys: 0.142 ± 0.013	0.617CysAsp: 0.617 ± 0.023	0.596CysGlu: 0.596 ± 0.026	0.478CysPhe: 0.478 ± 0.02	0.885CysGly: 0.885 ± 0.036	0.347CysHis: 0.347 ± 0.016	0.585CysIle: 0.585 ± 0.029	0.366CysLys: 0.366 ± 0.019	1.137CysLeu: 1.137 ± 0.035	0.197CysMet: 0.197 ± 0.015	0.286CysAsn: 0.286 ± 0.016	0.432CysPro: 0.432 ± 0.022	0.457CysGln: 0.457 ± 0.021	0.487CysArg: 0.487 ± 0.021	0.639CysSer: 0.639 ± 0.026	0.447CysThr: 0.447 ± 0.021	0.744CysVal: 0.744 ± 0.033	0.102CysTrp: 0.102 ± 0.01	0.308CysTyr: 0.308 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.907AspAla: 4.907 ± 0.08	0.532AspCys: 0.532 ± 0.025	3.085AspAsp: 3.085 ± 0.081	3.89AspGlu: 3.89 ± 0.061	2.482AspPhe: 2.482 ± 0.047	3.618AspGly: 3.618 ± 0.082	1.258AspHis: 1.258 ± 0.056	4.028AspIle: 4.028 ± 0.076	2.873AspLys: 2.873 ± 0.052	5.688AspLeu: 5.688 ± 0.074	1.46AspMet: 1.46 ± 0.041	2.177AspAsn: 2.177 ± 0.067	2.104AspPro: 2.104 ± 0.049	2.39AspGln: 2.39 ± 0.05	2.494AspArg: 2.494 ± 0.05	3.222AspSer: 3.222 ± 0.063	2.933AspThr: 2.933 ± 0.067	4.176AspVal: 4.176 ± 0.067	0.879AspTrp: 0.879 ± 0.03	1.845AspTyr: 1.845 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.675GluAla: 5.675 ± 0.091	0.551GluCys: 0.551 ± 0.023	3.041GluAsp: 3.041 ± 0.059	4.084GluGlu: 4.084 ± 0.091	2.285GluPhe: 2.285 ± 0.046	3.773GluGly: 3.773 ± 0.07	1.52GluHis: 1.52 ± 0.042	3.554GluIle: 3.554 ± 0.066	3.812GluLys: 3.812 ± 0.069	6.458GluLeu: 6.458 ± 0.091	1.639GluMet: 1.639 ± 0.043	2.567GluAsn: 2.567 ± 0.054	1.901GluPro: 1.901 ± 0.046	3.309GluGln: 3.309 ± 0.06	3.454GluArg: 3.454 ± 0.073	3.898GluSer: 3.898 ± 0.074	3.133GluThr: 3.133 ± 0.056	4.091GluVal: 4.091 ± 0.071	0.737GluTrp: 0.737 ± 0.026	1.661GluTyr: 1.661 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.58PheAla: 3.58 ± 0.065	0.553PheCys: 0.553 ± 0.028	2.807PheAsp: 2.807 ± 0.059	2.449PheGlu: 2.449 ± 0.048	1.818PhePhe: 1.818 ± 0.059	3.137PheGly: 3.137 ± 0.058	0.838PheHis: 0.838 ± 0.033	2.681PheIle: 2.681 ± 0.051	1.739PheLys: 1.739 ± 0.043	3.761PheLeu: 3.761 ± 0.069	1.068PheMet: 1.068 ± 0.033	1.858PheAsn: 1.858 ± 0.043	1.528PhePro: 1.528 ± 0.041	1.378PheGln: 1.378 ± 0.037	1.678PheArg: 1.678 ± 0.044	3.376PheSer: 3.376 ± 0.06	2.242PheThr: 2.242 ± 0.055	2.931PheVal: 2.931 ± 0.058	0.52PheTrp: 0.52 ± 0.028	1.342PheTyr: 1.342 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	5.652GlyAla: 5.652 ± 0.081	0.836GlyCys: 0.836 ± 0.03	3.695GlyAsp: 3.695 ± 0.077	4.094GlyGlu: 4.094 ± 0.064	3.33GlyPhe: 3.33 ± 0.054	4.808GlyGly: 4.808 ± 0.097	1.678GlyHis: 1.678 ± 0.058	4.713GlyIle: 4.713 ± 0.073	3.734GlyLys: 3.734 ± 0.068	7.272GlyLeu: 7.272 ± 0.098	2.015GlyMet: 2.015 ± 0.047	2.431GlyAsn: 2.431 ± 0.072	1.822GlyPro: 1.822 ± 0.048	2.831GlyGln: 2.831 ± 0.053	3.343GlyArg: 3.343 ± 0.067	4.07GlySer: 4.07 ± 0.101	3.398GlyThr: 3.398 ± 0.095	5.477GlyVal: 5.477 ± 0.078	0.896GlyTrp: 0.896 ± 0.036	2.424GlyTyr: 2.424 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.728HisAla: 1.728 ± 0.043	0.319HisCys: 0.319 ± 0.018	1.231HisAsp: 1.231 ± 0.059	1.144HisGlu: 1.144 ± 0.038	1.217HisPhe: 1.217 ± 0.034	1.492HisGly: 1.492 ± 0.035	0.739HisHis: 0.739 ± 0.031	1.451HisIle: 1.451 ± 0.036	1.102HisLys: 1.102 ± 0.053	2.446HisLeu: 2.446 ± 0.046	0.537HisMet: 0.537 ± 0.022	0.848HisAsn: 0.848 ± 0.03	1.243HisPro: 1.243 ± 0.032	1.121HisGln: 1.121 ± 0.04	1.056HisArg: 1.056 ± 0.033	1.487HisSer: 1.487 ± 0.04	1.195HisThr: 1.195 ± 0.034	1.273HisVal: 1.273 ± 0.039	0.372HisTrp: 0.372 ± 0.021	0.856HisTyr: 0.856 ± 0.029	0.001HisXaa: 0.001 ± 0.001
Ile	6.241IleAla: 6.241 ± 0.084	0.651IleCys: 0.651 ± 0.028	4.049IleAsp: 4.049 ± 0.067	4.435IleGlu: 4.435 ± 0.078	2.187IlePhe: 2.187 ± 0.057	4.763IleGly: 4.763 ± 0.088	1.282IleHis: 1.282 ± 0.032	3.524IleIle: 3.524 ± 0.066	3.152IleLys: 3.152 ± 0.06	5.655IleLeu: 5.655 ± 0.086	1.454IleMet: 1.454 ± 0.037	2.782IleAsn: 2.782 ± 0.061	2.592IlePro: 2.592 ± 0.058	2.513IleGln: 2.513 ± 0.054	3.12IleArg: 3.12 ± 0.053	4.325IleSer: 4.325 ± 0.071	3.62IleThr: 3.62 ± 0.083	4.195IleVal: 4.195 ± 0.062	0.629IleTrp: 0.629 ± 0.026	1.529IleTyr: 1.529 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.954LysAla: 4.954 ± 0.079	0.298LysCys: 0.298 ± 0.016	2.92LysAsp: 2.92 ± 0.06	3.455LysGlu: 3.455 ± 0.068	1.227LysPhe: 1.227 ± 0.041	3.451LysGly: 3.451 ± 0.08	1.223LysHis: 1.223 ± 0.032	2.893LysIle: 2.893 ± 0.058	2.933LysLys: 2.933 ± 0.071	4.529LysLeu: 4.529 ± 0.068	1.501LysMet: 1.501 ± 0.036	2.075LysAsn: 2.075 ± 0.045	2.053LysPro: 2.053 ± 0.052	2.604LysGln: 2.604 ± 0.056	2.841LysArg: 2.841 ± 0.061	3.141LysSer: 3.141 ± 0.055	3.071LysThr: 3.071 ± 0.057	3.648LysVal: 3.648 ± 0.071	0.539LysTrp: 0.539 ± 0.024	1.143LysTyr: 1.143 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	10.271LeuAla: 10.271 ± 0.13	1.098LeuCys: 1.098 ± 0.032	5.994LeuAsp: 5.994 ± 0.089	6.231LeuGlu: 6.231 ± 0.092	4.19LeuPhe: 4.19 ± 0.084	7.155LeuGly: 7.155 ± 0.109	2.154LeuHis: 2.154 ± 0.048	6.463LeuIle: 6.463 ± 0.097	5.295LeuLys: 5.295 ± 0.074	10.887LeuLeu: 10.887 ± 0.141	2.881LeuMet: 2.881 ± 0.059	4.606LeuAsn: 4.606 ± 0.073	4.858LeuPro: 4.858 ± 0.076	3.813LeuGln: 3.813 ± 0.07	4.494LeuArg: 4.494 ± 0.079	8.496LeuSer: 8.496 ± 0.107	5.98LeuThr: 5.98 ± 0.096	7.439LeuVal: 7.439 ± 0.099	1.066LeuTrp: 1.066 ± 0.038	2.666LeuTyr: 2.666 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.755MetAla: 2.755 ± 0.058	0.185MetCys: 0.185 ± 0.014	1.359MetAsp: 1.359 ± 0.036	1.271MetGlu: 1.271 ± 0.04	0.877MetPhe: 0.877 ± 0.029	1.913MetGly: 1.913 ± 0.05	0.479MetHis: 0.479 ± 0.021	1.544MetIle: 1.544 ± 0.049	1.443MetLys: 1.443 ± 0.035	2.733MetLeu: 2.733 ± 0.053	0.833MetMet: 0.833 ± 0.033	1.097MetAsn: 1.097 ± 0.032	1.307MetPro: 1.307 ± 0.036	1.091MetGln: 1.091 ± 0.032	1.299MetArg: 1.299 ± 0.034	2.08MetSer: 2.08 ± 0.045	1.841MetThr: 1.841 ± 0.045	1.871MetVal: 1.871 ± 0.047	0.203MetTrp: 0.203 ± 0.013	0.491MetTyr: 0.491 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.675AsnAla: 3.675 ± 0.075	0.346AsnCys: 0.346 ± 0.017	2.389AsnAsp: 2.389 ± 0.06	2.337AsnGlu: 2.337 ± 0.054	1.346AsnPhe: 1.346 ± 0.037	2.814AsnGly: 2.814 ± 0.067	0.904AsnHis: 0.904 ± 0.026	2.617AsnIle: 2.617 ± 0.057	2.078AsnLys: 2.078 ± 0.049	3.922AsnLeu: 3.922 ± 0.078	1.018AsnMet: 1.018 ± 0.032	1.752AsnAsn: 1.752 ± 0.053	1.95AsnPro: 1.95 ± 0.048	1.959AsnGln: 1.959 ± 0.051	2.001AsnArg: 2.001 ± 0.057	2.204AsnSer: 2.204 ± 0.056	2.569AsnThr: 2.569 ± 0.07	2.588AsnVal: 2.588 ± 0.055	0.535AsnTrp: 0.535 ± 0.024	1.104AsnTyr: 1.104 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	3.147ProAla: 3.147 ± 0.059	0.334ProCys: 0.334 ± 0.019	2.42ProAsp: 2.42 ± 0.052	3.053ProGlu: 3.053 ± 0.07	1.817ProPhe: 1.817 ± 0.043	2.279ProGly: 2.279 ± 0.049	0.916ProHis: 0.916 ± 0.034	2.626ProIle: 2.626 ± 0.053	2.116ProLys: 2.116 ± 0.047	4.113ProLeu: 4.113 ± 0.065	1.113ProMet: 1.113 ± 0.035	1.842ProAsn: 1.842 ± 0.04	1.214ProPro: 1.214 ± 0.04	1.415ProGln: 1.415 ± 0.041	1.372ProArg: 1.372 ± 0.041	2.702ProSer: 2.702 ± 0.055	2.252ProThr: 2.252 ± 0.05	3.03ProVal: 3.03 ± 0.054	0.516ProTrp: 0.516 ± 0.022	1.205ProTyr: 1.205 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.499GlnAla: 4.499 ± 0.082	0.366GlnCys: 0.366 ± 0.021	2.146GlnAsp: 2.146 ± 0.052	2.503GlnGlu: 2.503 ± 0.05	1.657GlnPhe: 1.657 ± 0.037	3.005GlnGly: 3.005 ± 0.063	1.141GlnHis: 1.141 ± 0.032	2.483GlnIle: 2.483 ± 0.048	2.192GlnLys: 2.192 ± 0.049	4.62GlnLeu: 4.62 ± 0.085	1.001GlnMet: 1.001 ± 0.03	1.69GlnAsn: 1.69 ± 0.044	1.637GlnPro: 1.637 ± 0.045	2.626GlnGln: 2.626 ± 0.068	2.327GlnArg: 2.327 ± 0.047	2.958GlnSer: 2.958 ± 0.057	2.425GlnThr: 2.425 ± 0.058	3.135GlnVal: 3.135 ± 0.055	0.631GlnTrp: 0.631 ± 0.025	1.179GlnTyr: 1.179 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	3.702ArgAla: 3.702 ± 0.067	0.467ArgCys: 0.467 ± 0.023	2.456ArgAsp: 2.456 ± 0.047	2.809ArgGlu: 2.809 ± 0.057	2.443ArgPhe: 2.443 ± 0.058	2.706ArgGly: 2.706 ± 0.06	1.282ArgHis: 1.282 ± 0.038	3.149ArgIle: 3.149 ± 0.061	2.216ArgLys: 2.216 ± 0.05	5.595ArgLeu: 5.595 ± 0.084	1.268ArgMet: 1.268 ± 0.037	1.785ArgAsn: 1.785 ± 0.045	1.854ArgPro: 1.854 ± 0.044	2.351ArgGln: 2.351 ± 0.059	2.564ArgArg: 2.564 ± 0.06	2.909ArgSer: 2.909 ± 0.059	2.224ArgThr: 2.224 ± 0.045	3.413ArgVal: 3.413 ± 0.062	0.641ArgTrp: 0.641 ± 0.025	1.705ArgTyr: 1.705 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	5.768SerAla: 5.768 ± 0.093	0.562SerCys: 0.562 ± 0.024	3.812SerAsp: 3.812 ± 0.065	3.885SerGlu: 3.885 ± 0.068	2.861SerPhe: 2.861 ± 0.052	4.842SerGly: 4.842 ± 0.095	1.616SerHis: 1.616 ± 0.038	4.308SerIle: 4.308 ± 0.08	3.177SerLys: 3.177 ± 0.059	7.65SerLeu: 7.65 ± 0.09	1.821SerMet: 1.821 ± 0.048	2.598SerAsn: 2.598 ± 0.056	2.54SerPro: 2.54 ± 0.06	2.973SerGln: 2.973 ± 0.059	3.187SerArg: 3.187 ± 0.053	4.671SerSer: 4.671 ± 0.104	3.512SerThr: 3.512 ± 0.074	4.953SerVal: 4.953 ± 0.08	0.79SerTrp: 0.79 ± 0.03	1.919SerTyr: 1.919 ± 0.046	0.001SerXaa: 0.001 ± 0.001
Thr	4.523ThrAla: 4.523 ± 0.09	0.489ThrCys: 0.489 ± 0.027	2.938ThrAsp: 2.938 ± 0.063	3.062ThrGlu: 3.062 ± 0.054	2.176ThrPhe: 2.176 ± 0.053	4.157ThrGly: 4.157 ± 0.126	1.284ThrHis: 1.284 ± 0.038	3.145ThrIle: 3.145 ± 0.068	2.402ThrLys: 2.402 ± 0.047	6.875ThrLeu: 6.875 ± 0.11	1.199ThrMet: 1.199 ± 0.034	1.964ThrAsn: 1.964 ± 0.062	2.907ThrPro: 2.907 ± 0.05	2.583ThrGln: 2.583 ± 0.057	2.335ThrArg: 2.335 ± 0.05	3.497ThrSer: 3.497 ± 0.077	2.979ThrThr: 2.979 ± 0.088	3.841ThrVal: 3.841 ± 0.105	0.571ThrTrp: 0.571 ± 0.019	1.428ThrTyr: 1.428 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	6.62ValAla: 6.62 ± 0.09	0.836ValCys: 0.836 ± 0.031	4.092ValAsp: 4.092 ± 0.059	4.345ValGlu: 4.345 ± 0.068	3.056ValPhe: 3.056 ± 0.059	4.793ValGly: 4.793 ± 0.081	1.276ValHis: 1.276 ± 0.039	4.732ValIle: 4.732 ± 0.067	3.362ValLys: 3.362 ± 0.056	7.267ValLeu: 7.267 ± 0.101	2.058ValMet: 2.058 ± 0.05	2.874ValAsn: 2.874 ± 0.058	2.663ValPro: 2.663 ± 0.058	2.264ValGln: 2.264 ± 0.052	3.191ValArg: 3.191 ± 0.054	5.329ValSer: 5.329 ± 0.089	4.129ValThr: 4.129 ± 0.104	5.502ValVal: 5.502 ± 0.093	0.83ValTrp: 0.83 ± 0.027	1.85ValTyr: 1.85 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.79TrpAla: 0.79 ± 0.027	0.161TrpCys: 0.161 ± 0.012	0.558TrpAsp: 0.558 ± 0.022	0.541TrpGlu: 0.541 ± 0.02	0.584TrpPhe: 0.584 ± 0.026	0.766TrpGly: 0.766 ± 0.027	0.339TrpHis: 0.339 ± 0.017	0.704TrpIle: 0.704 ± 0.03	0.493TrpLys: 0.493 ± 0.019	1.723TrpLeu: 1.723 ± 0.046	0.362TrpMet: 0.362 ± 0.021	0.397TrpAsn: 0.397 ± 0.019	0.489TrpPro: 0.489 ± 0.025	0.857TrpGln: 0.857 ± 0.032	0.708TrpArg: 0.708 ± 0.026	0.768TrpSer: 0.768 ± 0.026	0.466TrpThr: 0.466 ± 0.024	0.927TrpVal: 0.927 ± 0.033	0.17TrpTrp: 0.17 ± 0.014	0.306TrpTyr: 0.306 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.287TyrAla: 2.287 ± 0.048	0.346TyrCys: 0.346 ± 0.017	1.61TyrAsp: 1.61 ± 0.044	1.597TyrGlu: 1.597 ± 0.039	1.359TyrPhe: 1.359 ± 0.04	2.014TyrGly: 2.014 ± 0.042	0.756TyrHis: 0.756 ± 0.028	1.407TyrIle: 1.407 ± 0.039	1.225TyrLys: 1.225 ± 0.032	3.226TyrLeu: 3.226 ± 0.061	0.552TyrMet: 0.552 ± 0.028	0.889TyrAsn: 0.889 ± 0.031	1.311TyrPro: 1.311 ± 0.039	1.7TyrGln: 1.7 ± 0.043	1.687TyrArg: 1.687 ± 0.04	1.793TyrSer: 1.793 ± 0.042	1.387TyrThr: 1.387 ± 0.04	1.774TyrVal: 1.774 ± 0.042	0.423TyrTrp: 0.423 ± 0.022	0.921TyrTyr: 0.921 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3066 proteins (1026813 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---