Amino acid dipepetide frequency for Ktedonobacter racemifer DSM 44963

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.451AlaAla: 8.451 ± 0.07	1.226AlaCys: 1.226 ± 0.02	3.9AlaAsp: 3.9 ± 0.035	5.209AlaGlu: 5.209 ± 0.045	3.668AlaPhe: 3.668 ± 0.036	6.349AlaGly: 6.349 ± 0.055	2.624AlaHis: 2.624 ± 0.028	5.323AlaIle: 5.323 ± 0.039	2.842AlaLys: 2.842 ± 0.033	11.695AlaLeu: 11.695 ± 0.067	2.213AlaMet: 2.213 ± 0.029	2.887AlaAsn: 2.887 ± 0.034	4.144AlaPro: 4.144 ± 0.041	4.921AlaGln: 4.921 ± 0.039	6.522AlaArg: 6.522 ± 0.047	6.304AlaSer: 6.304 ± 0.043	5.382AlaThr: 5.382 ± 0.044	5.686AlaVal: 5.686 ± 0.043	1.54AlaTrp: 1.54 ± 0.024	2.913AlaTyr: 2.913 ± 0.031	0.0AlaXaa: 0.0 ± 0.0
Cys	1.0CysAla: 1.0 ± 0.018	0.22CysCys: 0.22 ± 0.009	0.48CysAsp: 0.48 ± 0.012	0.58CysGlu: 0.58 ± 0.014	0.423CysPhe: 0.423 ± 0.012	1.077CysGly: 1.077 ± 0.019	0.343CysHis: 0.343 ± 0.01	0.56CysIle: 0.56 ± 0.013	0.338CysLys: 0.338 ± 0.011	1.189CysLeu: 1.189 ± 0.023	0.214CysMet: 0.214 ± 0.008	0.306CysAsn: 0.306 ± 0.01	0.6CysPro: 0.6 ± 0.012	0.582CysGln: 0.582 ± 0.014	0.647CysArg: 0.647 ± 0.017	0.748CysSer: 0.748 ± 0.016	0.6CysThr: 0.6 ± 0.015	0.705CysVal: 0.705 ± 0.016	0.199CysTrp: 0.199 ± 0.008	0.356CysTyr: 0.356 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.309AspAla: 4.309 ± 0.036	0.414AspCys: 0.414 ± 0.011	2.12AspAsp: 2.12 ± 0.029	3.253AspGlu: 3.253 ± 0.034	1.655AspPhe: 1.655 ± 0.024	3.412AspGly: 3.412 ± 0.041	1.149AspHis: 1.149 ± 0.019	2.704AspIle: 2.704 ± 0.03	1.371AspLys: 1.371 ± 0.024	5.076AspLeu: 5.076 ± 0.044	1.036AspMet: 1.036 ± 0.016	1.269AspAsn: 1.269 ± 0.022	2.769AspPro: 2.769 ± 0.031	2.047AspGln: 2.047 ± 0.026	2.503AspArg: 2.503 ± 0.028	2.036AspSer: 2.036 ± 0.028	2.477AspThr: 2.477 ± 0.029	3.227AspVal: 3.227 ± 0.03	0.812AspTrp: 0.812 ± 0.016	1.469AspTyr: 1.469 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	6.312GluAla: 6.312 ± 0.054	0.528GluCys: 0.528 ± 0.014	2.601GluAsp: 2.601 ± 0.036	4.798GluGlu: 4.798 ± 0.057	1.397GluPhe: 1.397 ± 0.021	3.849GluGly: 3.849 ± 0.042	1.999GluHis: 1.999 ± 0.025	3.235GluIle: 3.235 ± 0.033	2.558GluLys: 2.558 ± 0.033	5.775GluLeu: 5.775 ± 0.051	1.519GluMet: 1.519 ± 0.023	1.705GluAsn: 1.705 ± 0.025	2.468GluPro: 2.468 ± 0.031	4.559GluGln: 4.559 ± 0.042	5.259GluArg: 5.259 ± 0.052	2.701GluSer: 2.701 ± 0.034	3.299GluThr: 3.299 ± 0.034	4.068GluVal: 4.068 ± 0.04	0.774GluTrp: 0.774 ± 0.016	1.583GluTyr: 1.583 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.478PheAla: 3.478 ± 0.03	0.53PheCys: 0.53 ± 0.012	1.785PheAsp: 1.785 ± 0.024	1.9PheGlu: 1.9 ± 0.025	1.681PhePhe: 1.681 ± 0.027	2.669PheGly: 2.669 ± 0.032	0.935PheHis: 0.935 ± 0.017	1.848PheIle: 1.848 ± 0.025	1.043PheLys: 1.043 ± 0.017	4.182PheLeu: 4.182 ± 0.039	0.716PheMet: 0.716 ± 0.016	1.072PheAsn: 1.072 ± 0.021	1.782PhePro: 1.782 ± 0.022	1.435PheGln: 1.435 ± 0.025	1.858PheArg: 1.858 ± 0.023	2.57PheSer: 2.57 ± 0.03	2.217PheThr: 2.217 ± 0.028	2.519PheVal: 2.519 ± 0.025	0.649PheTrp: 0.649 ± 0.015	1.175PheTyr: 1.175 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	5.754GlyAla: 5.754 ± 0.053	0.813GlyCys: 0.813 ± 0.018	2.887GlyAsp: 2.887 ± 0.03	4.097GlyGlu: 4.097 ± 0.042	2.61GlyPhe: 2.61 ± 0.032	5.146GlyGly: 5.146 ± 0.058	1.823GlyHis: 1.823 ± 0.026	4.326GlyIle: 4.326 ± 0.043	3.521GlyLys: 3.521 ± 0.036	7.277GlyLeu: 7.277 ± 0.055	1.923GlyMet: 1.923 ± 0.024	2.411GlyAsn: 2.411 ± 0.032	2.545GlyPro: 2.545 ± 0.028	3.311GlyGln: 3.311 ± 0.029	4.337GlyArg: 4.337 ± 0.041	4.54GlySer: 4.54 ± 0.046	4.337GlyThr: 4.337 ± 0.048	4.793GlyVal: 4.793 ± 0.042	1.324GlyTrp: 1.324 ± 0.021	2.616GlyTyr: 2.616 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	2.413HisAla: 2.413 ± 0.024	0.351HisCys: 0.351 ± 0.011	1.182HisAsp: 1.182 ± 0.016	1.599HisGlu: 1.599 ± 0.023	1.07HisPhe: 1.07 ± 0.018	1.825HisGly: 1.825 ± 0.022	0.84HisHis: 0.84 ± 0.016	1.637HisIle: 1.637 ± 0.021	0.872HisLys: 0.872 ± 0.017	3.273HisLeu: 3.273 ± 0.033	0.609HisMet: 0.609 ± 0.012	0.787HisAsn: 0.787 ± 0.019	1.77HisPro: 1.77 ± 0.025	1.288HisGln: 1.288 ± 0.021	1.68HisArg: 1.68 ± 0.024	1.389HisSer: 1.389 ± 0.024	1.732HisThr: 1.732 ± 0.029	1.728HisVal: 1.728 ± 0.024	0.482HisTrp: 0.482 ± 0.012	0.905HisTyr: 0.905 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	5.645IleAla: 5.645 ± 0.041	0.634IleCys: 0.634 ± 0.014	2.793IleAsp: 2.793 ± 0.032	3.452IleGlu: 3.452 ± 0.038	1.978IlePhe: 1.978 ± 0.029	4.034IleGly: 4.034 ± 0.038	1.342IleHis: 1.342 ± 0.019	2.852IleIle: 2.852 ± 0.036	1.725IleLys: 1.725 ± 0.025	5.361IleLeu: 5.361 ± 0.048	0.962IleMet: 0.962 ± 0.019	1.663IleAsn: 1.663 ± 0.025	2.769IlePro: 2.769 ± 0.028	2.291IleGln: 2.291 ± 0.024	2.944IleArg: 2.944 ± 0.029	3.338IleSer: 3.338 ± 0.035	3.182IleThr: 3.182 ± 0.032	3.923IleVal: 3.923 ± 0.036	0.748IleTrp: 0.748 ± 0.015	1.579IleTyr: 1.579 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	3.35LysAla: 3.35 ± 0.037	0.282LysCys: 0.282 ± 0.009	1.629LysAsp: 1.629 ± 0.024	2.286LysGlu: 2.286 ± 0.026	0.772LysPhe: 0.772 ± 0.015	2.548LysGly: 2.548 ± 0.031	1.018LysHis: 1.018 ± 0.019	1.624LysIle: 1.624 ± 0.025	1.959LysLys: 1.959 ± 0.032	3.341LysLeu: 3.341 ± 0.035	0.813LysMet: 0.813 ± 0.015	1.131LysAsn: 1.131 ± 0.021	1.856LysPro: 1.856 ± 0.027	2.297LysGln: 2.297 ± 0.027	3.143LysArg: 3.143 ± 0.033	1.874LysSer: 1.874 ± 0.025	2.173LysThr: 2.173 ± 0.026	2.195LysVal: 2.195 ± 0.029	0.468LysTrp: 0.468 ± 0.012	0.932LysTyr: 0.932 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	11.619LeuAla: 11.619 ± 0.069	1.326LeuCys: 1.326 ± 0.022	5.159LeuAsp: 5.159 ± 0.037	6.251LeuGlu: 6.251 ± 0.054	4.046LeuPhe: 4.046 ± 0.04	7.316LeuGly: 7.316 ± 0.06	3.171LeuHis: 3.171 ± 0.037	5.497LeuIle: 5.497 ± 0.046	3.792LeuLys: 3.792 ± 0.035	13.588LeuLeu: 13.588 ± 0.106	2.163LeuMet: 2.163 ± 0.027	3.139LeuAsn: 3.139 ± 0.031	6.224LeuPro: 6.224 ± 0.046	5.181LeuGln: 5.181 ± 0.041	7.208LeuArg: 7.208 ± 0.057	7.41LeuSer: 7.41 ± 0.05	6.252LeuThr: 6.252 ± 0.047	7.644LeuVal: 7.644 ± 0.057	1.54LeuTrp: 1.54 ± 0.026	3.016LeuTyr: 3.016 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.085MetAla: 2.085 ± 0.026	0.182MetCys: 0.182 ± 0.007	0.904MetAsp: 0.904 ± 0.016	1.158MetGlu: 1.158 ± 0.017	0.623MetPhe: 0.623 ± 0.013	1.485MetGly: 1.485 ± 0.022	0.607MetHis: 0.607 ± 0.014	1.019MetIle: 1.019 ± 0.019	0.944MetLys: 0.944 ± 0.018	2.635MetLeu: 2.635 ± 0.031	0.499MetMet: 0.499 ± 0.012	0.743MetAsn: 0.743 ± 0.014	1.256MetPro: 1.256 ± 0.02	1.297MetGln: 1.297 ± 0.02	1.673MetArg: 1.673 ± 0.02	1.503MetSer: 1.503 ± 0.021	1.343MetThr: 1.343 ± 0.02	1.401MetVal: 1.401 ± 0.021	0.231MetTrp: 0.231 ± 0.008	0.508MetTyr: 0.508 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.998AsnAla: 2.998 ± 0.034	0.3AsnCys: 0.3 ± 0.01	1.431AsnAsp: 1.431 ± 0.021	1.668AsnGlu: 1.668 ± 0.021	1.024AsnPhe: 1.024 ± 0.018	2.412AsnGly: 2.412 ± 0.034	0.648AsnHis: 0.648 ± 0.016	1.797AsnIle: 1.797 ± 0.026	1.111AsnLys: 1.111 ± 0.02	2.966AsnLeu: 2.966 ± 0.034	0.702AsnMet: 0.702 ± 0.014	1.114AsnAsn: 1.114 ± 0.023	1.799AsnPro: 1.799 ± 0.025	1.449AsnGln: 1.449 ± 0.025	1.732AsnArg: 1.732 ± 0.024	1.654AsnSer: 1.654 ± 0.028	1.927AsnThr: 1.927 ± 0.029	2.026AsnVal: 2.026 ± 0.027	0.568AsnTrp: 0.568 ± 0.014	0.992AsnTyr: 0.992 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	4.575ProAla: 4.575 ± 0.04	0.412ProCys: 0.412 ± 0.013	2.84ProAsp: 2.84 ± 0.028	3.781ProGlu: 3.781 ± 0.043	2.014ProPhe: 2.014 ± 0.025	3.905ProGly: 3.905 ± 0.038	1.408ProHis: 1.408 ± 0.021	2.318ProIle: 2.318 ± 0.027	1.515ProLys: 1.515 ± 0.022	5.577ProLeu: 5.577 ± 0.038	0.954ProMet: 0.954 ± 0.017	1.467ProAsn: 1.467 ± 0.024	2.683ProPro: 2.683 ± 0.038	2.601ProGln: 2.601 ± 0.028	2.818ProArg: 2.818 ± 0.03	3.244ProSer: 3.244 ± 0.034	3.356ProThr: 3.356 ± 0.043	3.377ProVal: 3.377 ± 0.035	0.727ProTrp: 0.727 ± 0.015	1.448ProTyr: 1.448 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	5.914GlnAla: 5.914 ± 0.046	0.437GlnCys: 0.437 ± 0.012	2.092GlnAsp: 2.092 ± 0.024	3.694GlnGlu: 3.694 ± 0.042	1.483GlnPhe: 1.483 ± 0.022	3.674GlnGly: 3.674 ± 0.035	1.498GlnHis: 1.498 ± 0.022	2.375GlnIle: 2.375 ± 0.028	1.85GlnLys: 1.85 ± 0.026	4.9GlnLeu: 4.9 ± 0.038	1.145GlnMet: 1.145 ± 0.018	1.361GlnAsn: 1.361 ± 0.02	2.655GlnPro: 2.655 ± 0.035	3.644GlnGln: 3.644 ± 0.043	4.074GlnArg: 4.074 ± 0.044	2.593GlnSer: 2.593 ± 0.03	2.835GlnThr: 2.835 ± 0.027	3.74GlnVal: 3.74 ± 0.04	0.753GlnTrp: 0.753 ± 0.017	1.329GlnTyr: 1.329 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	5.733ArgAla: 5.733 ± 0.045	0.73ArgCys: 0.73 ± 0.015	2.95ArgAsp: 2.95 ± 0.035	4.623ArgGlu: 4.623 ± 0.041	2.646ArgPhe: 2.646 ± 0.03	3.947ArgGly: 3.947 ± 0.038	1.791ArgHis: 1.791 ± 0.022	3.344ArgIle: 3.344 ± 0.032	2.762ArgLys: 2.762 ± 0.032	7.724ArgLeu: 7.724 ± 0.069	1.554ArgMet: 1.554 ± 0.023	1.841ArgAsn: 1.841 ± 0.024	2.935ArgPro: 2.935 ± 0.033	3.622ArgGln: 3.622 ± 0.04	5.081ArgArg: 5.081 ± 0.047	3.641ArgSer: 3.641 ± 0.034	3.457ArgThr: 3.457 ± 0.033	4.341ArgVal: 4.341 ± 0.042	1.26ArgTrp: 1.26 ± 0.027	2.196ArgTyr: 2.196 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	5.235SerAla: 5.235 ± 0.043	0.665SerCys: 0.665 ± 0.013	2.772SerAsp: 2.772 ± 0.032	3.266SerGlu: 3.266 ± 0.037	2.453SerPhe: 2.453 ± 0.028	4.579SerGly: 4.579 ± 0.038	1.609SerHis: 1.609 ± 0.021	3.312SerIle: 3.312 ± 0.032	2.035SerLys: 2.035 ± 0.026	6.876SerLeu: 6.876 ± 0.052	1.493SerMet: 1.493 ± 0.02	1.937SerAsn: 1.937 ± 0.026	3.404SerPro: 3.404 ± 0.041	3.034SerGln: 3.034 ± 0.033	3.553SerArg: 3.553 ± 0.032	4.502SerSer: 4.502 ± 0.047	3.789SerThr: 3.789 ± 0.038	3.773SerVal: 3.773 ± 0.033	1.093SerTrp: 1.093 ± 0.019	1.882SerTyr: 1.882 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.666ThrAla: 4.666 ± 0.04	0.672ThrCys: 0.672 ± 0.014	2.291ThrAsp: 2.291 ± 0.029	2.65ThrGlu: 2.65 ± 0.032	2.402ThrPhe: 2.402 ± 0.028	4.336ThrGly: 4.336 ± 0.046	1.695ThrHis: 1.695 ± 0.025	3.462ThrIle: 3.462 ± 0.04	1.648ThrLys: 1.648 ± 0.023	7.225ThrLeu: 7.225 ± 0.049	1.169ThrMet: 1.169 ± 0.019	1.845ThrAsn: 1.845 ± 0.028	3.889ThrPro: 3.889 ± 0.042	2.73ThrGln: 2.73 ± 0.031	3.608ThrArg: 3.608 ± 0.034	4.017ThrSer: 4.017 ± 0.044	3.866ThrThr: 3.866 ± 0.038	3.812ThrVal: 3.812 ± 0.04	1.023ThrTrp: 1.023 ± 0.019	1.884ThrTyr: 1.884 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	6.385ValAla: 6.385 ± 0.047	0.814ValCys: 0.814 ± 0.016	3.118ValAsp: 3.118 ± 0.027	4.057ValGlu: 4.057 ± 0.043	2.368ValPhe: 2.368 ± 0.026	4.67ValGly: 4.67 ± 0.045	1.568ValHis: 1.568 ± 0.022	3.731ValIle: 3.731 ± 0.039	2.269ValLys: 2.269 ± 0.026	7.483ValLeu: 7.483 ± 0.049	1.452ValMet: 1.452 ± 0.021	1.973ValAsn: 1.973 ± 0.024	3.343ValPro: 3.343 ± 0.032	3.057ValGln: 3.057 ± 0.033	4.224ValArg: 4.224 ± 0.039	4.413ValSer: 4.413 ± 0.037	4.0ValThr: 4.0 ± 0.037	4.978ValVal: 4.978 ± 0.044	0.919ValTrp: 0.919 ± 0.017	1.856ValTyr: 1.856 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	1.09TrpAla: 1.09 ± 0.02	0.235TrpCys: 0.235 ± 0.009	0.664TrpAsp: 0.664 ± 0.017	0.885TrpGlu: 0.885 ± 0.015	0.64TrpPhe: 0.64 ± 0.017	0.972TrpGly: 0.972 ± 0.017	0.486TrpHis: 0.486 ± 0.013	0.803TrpIle: 0.803 ± 0.015	0.579TrpLys: 0.579 ± 0.015	2.072TrpLeu: 2.072 ± 0.029	0.391TrpMet: 0.391 ± 0.011	0.639TrpAsn: 0.639 ± 0.016	0.586TrpPro: 0.586 ± 0.014	1.011TrpGln: 1.011 ± 0.019	1.176TrpArg: 1.176 ± 0.02	1.148TrpSer: 1.148 ± 0.022	0.796TrpThr: 0.796 ± 0.016	0.91TrpVal: 0.91 ± 0.019	0.315TrpTrp: 0.315 ± 0.009	0.54TrpTyr: 0.54 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.785TyrAla: 2.785 ± 0.031	0.399TyrCys: 0.399 ± 0.012	1.508TyrAsp: 1.508 ± 0.021	1.778TyrGlu: 1.778 ± 0.027	1.09TyrPhe: 1.09 ± 0.019	2.187TyrGly: 2.187 ± 0.026	0.88TyrHis: 0.88 ± 0.017	1.449TyrIle: 1.449 ± 0.021	0.956TyrLys: 0.956 ± 0.018	3.328TyrLeu: 3.328 ± 0.033	0.566TyrMet: 0.566 ± 0.014	1.028TyrAsn: 1.028 ± 0.021	1.545TyrPro: 1.545 ± 0.025	1.688TyrGln: 1.688 ± 0.022	2.14TyrArg: 2.14 ± 0.027	1.638TyrSer: 1.638 ± 0.021	1.869TyrThr: 1.869 ± 0.027	1.833TyrVal: 1.833 ± 0.024	0.512TyrTrp: 0.512 ± 0.012	1.011TyrTyr: 1.011 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 11211 proteins (3395074 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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