Talaromyces rugulosus

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina;

Average proteome isoelectric point is 6.23

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11830 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A7H8QK42|A0A7H8QK42_9EURO Uncharacterized protein OS=Talaromyces rugulosus OX=121627 GN=TRUGW13939_01351 PE=3 SV=1
MM1 pKa = 7.83AKK3 pKa = 9.73TIFGSLVLAVVLKK16 pKa = 10.62LATANPVAQPAITSAPNLLEE36 pKa = 4.53KK37 pKa = 10.47RR38 pKa = 11.84AASCTFSGSDD48 pKa = 3.43GAASASASQKK58 pKa = 9.18SCSTIVLSAVAVPSGTTLDD77 pKa = 3.99LSNLEE82 pKa = 4.95DD83 pKa = 3.72DD84 pKa = 3.78TTVIFEE90 pKa = 5.05GEE92 pKa = 4.45TTWGYY97 pKa = 9.82EE98 pKa = 3.95EE99 pKa = 4.42WDD101 pKa = 3.96GPLLQISGTGITVQGASGASLNPDD125 pKa = 3.45GARR128 pKa = 11.84WWDD131 pKa = 3.64GEE133 pKa = 4.05GSNDD137 pKa = 4.0GKK139 pKa = 9.34TKK141 pKa = 10.47PKK143 pKa = 10.29FFYY146 pKa = 10.74AHH148 pKa = 7.64DD149 pKa = 4.2LTSSSITDD157 pKa = 3.48LQIQNTPVQAVSINGCDD174 pKa = 3.55GLTITDD180 pKa = 3.54MTIDD184 pKa = 3.5NSAGDD189 pKa = 3.81SEE191 pKa = 5.43GGHH194 pKa = 5.48NTDD197 pKa = 3.99GFDD200 pKa = 3.29IGSSSNVTIIGANVYY215 pKa = 10.16NQDD218 pKa = 3.1DD219 pKa = 4.24CVAVNSGTDD228 pKa = 3.08ITFSGGVCSGGHH240 pKa = 5.7GLSIGSVGGRR250 pKa = 11.84DD251 pKa = 4.03DD252 pKa = 3.81NTVDD256 pKa = 3.02TVTFEE261 pKa = 3.94NSEE264 pKa = 4.22VKK266 pKa = 10.78DD267 pKa = 3.68SVNGIRR273 pKa = 11.84IKK275 pKa = 10.81ASEE278 pKa = 4.49GDD280 pKa = 3.27TGTITGVTYY289 pKa = 10.81SGITLEE295 pKa = 4.72SISNRR300 pKa = 11.84ARR302 pKa = 11.84YY303 pKa = 8.76GVLIEE308 pKa = 3.96QNYY311 pKa = 10.96DD312 pKa = 3.31GGDD315 pKa = 3.66LNGGDD320 pKa = 4.18PTSGIPITDD329 pKa = 3.52LTIEE333 pKa = 4.59NISGDD338 pKa = 3.73GAVASDD344 pKa = 4.52GYY346 pKa = 11.22NIVIVCGSDD355 pKa = 3.28ACSDD359 pKa = 3.73WTWDD363 pKa = 3.69SVDD366 pKa = 3.35VTGGEE371 pKa = 4.68DD372 pKa = 4.3YY373 pKa = 11.34SDD375 pKa = 3.85CTNVPSVVSCSTT387 pKa = 3.13

Molecular weight: 39.56 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A7H8R0R0|A0A7H8R0R0_9EURO DNL-type domain-containing protein OS=Talaromyces rugulosus OX=121627 GN=TRUGW13939_06469 PE=4 SV=1
MM1 pKa = 7.55TSHH4 pKa = 7.37SDD6 pKa = 3.46PQKK9 pKa = 10.92DD10 pKa = 3.52PNSRR14 pKa = 11.84VPLAPVLHH22 pKa = 6.24RR23 pKa = 11.84VWATSTPYY31 pKa = 9.52TASIQANIRR40 pKa = 11.84SLDD43 pKa = 3.24PRR45 pKa = 11.84RR46 pKa = 11.84PHH48 pKa = 7.02VGAHH52 pKa = 6.37HH53 pKa = 6.99SDD55 pKa = 2.76HH56 pKa = 5.75TQRR59 pKa = 11.84ARR61 pKa = 11.84YY62 pKa = 9.18IGGPSATLLLHH73 pKa = 7.22DD74 pKa = 5.55LLSCSSPACRR84 pKa = 11.84PAAQPGPRR92 pKa = 11.84AHH94 pKa = 7.44RR95 pKa = 11.84NQPGQGTRR103 pKa = 11.84SRR105 pKa = 11.84CKK107 pKa = 9.4YY108 pKa = 9.21VRR110 pKa = 11.84RR111 pKa = 11.84HH112 pKa = 4.94NALPNRR118 pKa = 11.84VCAKK122 pKa = 10.43LGALVPTGSRR132 pKa = 11.84VAATIPMFPRR142 pKa = 11.84EE143 pKa = 3.96HH144 pKa = 6.38VEE146 pKa = 3.83CVEE149 pKa = 4.07RR150 pKa = 11.84SEE152 pKa = 4.19HH153 pKa = 5.33TKK155 pKa = 10.6CLEE158 pKa = 4.02PGEE161 pKa = 4.39RR162 pKa = 11.84RR163 pKa = 11.84NADD166 pKa = 3.12SS167 pKa = 3.78

Molecular weight: 18.37 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11830

0

11830

6275300

12

9054

530.5

58.82

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.249 ± 0.019

1.221 ± 0.007

5.745 ± 0.014

6.035 ± 0.022

3.89 ± 0.014

6.68 ± 0.02

2.415 ± 0.01

5.283 ± 0.013

4.726 ± 0.019

9.093 ± 0.023

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.088 ± 0.008

3.959 ± 0.01

5.715 ± 0.024

4.102 ± 0.012

5.767 ± 0.016

8.428 ± 0.026

6.041 ± 0.014

6.162 ± 0.015

1.499 ± 0.009

2.905 ± 0.011
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski