Amino acid dipepetide frequency for Acidianus bottle-shaped virus (isolate Italy/Pozzuoli) (ABV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.259AlaCys: 0.259 ± 0.268
1.556AlaAsp: 1.556 ± 0.459
1.945AlaGlu: 1.945 ± 0.445
2.982AlaPhe: 2.982 ± 0.73
2.074AlaGly: 2.074 ± 0.588
0.259AlaHis: 0.259 ± 0.171
5.705AlaIle: 5.705 ± 0.911
3.241AlaLys: 3.241 ± 0.696
5.316AlaLeu: 5.316 ± 0.973
1.167AlaMet: 1.167 ± 0.449
3.241AlaAsn: 3.241 ± 0.564
2.982AlaPro: 2.982 ± 1.246
1.945AlaGln: 1.945 ± 0.541
1.685AlaArg: 1.685 ± 0.497
2.463AlaSer: 2.463 ± 0.513
1.685AlaThr: 1.685 ± 0.505
3.371AlaVal: 3.371 ± 0.714
0.259AlaTrp: 0.259 ± 0.2
3.63AlaTyr: 3.63 ± 0.636
0.0AlaXaa: 0.0 ± 0.0
Cys
0.259CysAla: 0.259 ± 0.201
0.259CysCys: 0.259 ± 0.169
0.648CysAsp: 0.648 ± 0.258
0.389CysGlu: 0.389 ± 0.212
0.389CysPhe: 0.389 ± 0.21
0.648CysGly: 0.648 ± 0.354
0.13CysHis: 0.13 ± 0.123
1.167CysIle: 1.167 ± 0.364
1.426CysLys: 1.426 ± 0.496
1.426CysLeu: 1.426 ± 0.579
0.259CysMet: 0.259 ± 0.194
0.0CysAsn: 0.0 ± 0.0
1.297CysPro: 1.297 ± 0.643
0.778CysGln: 0.778 ± 0.335
0.259CysArg: 0.259 ± 0.183
0.259CysSer: 0.259 ± 0.172
0.519CysThr: 0.519 ± 0.259
0.908CysVal: 0.908 ± 0.473
0.0CysTrp: 0.0 ± 0.0
0.648CysTyr: 0.648 ± 0.276
0.0CysXaa: 0.0 ± 0.0
Asp
1.815AspAla: 1.815 ± 0.428
0.519AspCys: 0.519 ± 0.265
2.204AspAsp: 2.204 ± 0.708
3.501AspGlu: 3.501 ± 0.939
4.149AspPhe: 4.149 ± 0.645
1.556AspGly: 1.556 ± 0.427
0.389AspHis: 0.389 ± 0.229
2.982AspIle: 2.982 ± 0.741
3.63AspLys: 3.63 ± 0.599
6.353AspLeu: 6.353 ± 0.841
0.778AspMet: 0.778 ± 0.419
2.852AspAsn: 2.852 ± 0.684
3.112AspPro: 3.112 ± 0.6
1.037AspGln: 1.037 ± 0.459
1.556AspArg: 1.556 ± 0.441
4.149AspSer: 4.149 ± 0.712
1.815AspThr: 1.815 ± 0.537
3.76AspVal: 3.76 ± 0.618
0.259AspTrp: 0.259 ± 0.234
3.501AspTyr: 3.501 ± 0.862
0.0AspXaa: 0.0 ± 0.0
Glu
2.334GluAla: 2.334 ± 0.498
1.297GluCys: 1.297 ± 0.478
2.334GluAsp: 2.334 ± 0.578
6.483GluGlu: 6.483 ± 1.46
2.593GluPhe: 2.593 ± 0.54
2.334GluGly: 2.334 ± 0.533
1.426GluHis: 1.426 ± 0.433
5.316GluIle: 5.316 ± 0.931
7.52GluLys: 7.52 ± 1.602
7.001GluLeu: 7.001 ± 1.12
1.945GluMet: 1.945 ± 0.459
4.408GluAsn: 4.408 ± 0.97
2.074GluPro: 2.074 ± 0.434
2.334GluGln: 2.334 ± 0.653
2.593GluArg: 2.593 ± 0.552
4.149GluSer: 4.149 ± 0.799
3.63GluThr: 3.63 ± 0.625
3.89GluVal: 3.89 ± 0.833
0.519GluTrp: 0.519 ± 0.225
3.241GluTyr: 3.241 ± 0.843
0.0GluXaa: 0.0 ± 0.0
Phe
4.927PheAla: 4.927 ± 1.161
0.389PheCys: 0.389 ± 0.277
4.408PheAsp: 4.408 ± 0.734
2.982PheGlu: 2.982 ± 0.499
2.204PhePhe: 2.204 ± 0.568
2.723PheGly: 2.723 ± 0.639
0.259PheHis: 0.259 ± 0.172
4.667PheIle: 4.667 ± 0.855
3.76PheLys: 3.76 ± 0.665
6.612PheLeu: 6.612 ± 1.069
1.167PheMet: 1.167 ± 0.363
4.019PheAsn: 4.019 ± 0.729
1.037PhePro: 1.037 ± 0.4
1.426PheGln: 1.426 ± 0.346
1.685PheArg: 1.685 ± 0.441
3.89PheSer: 3.89 ± 0.828
3.241PheThr: 3.241 ± 0.68
2.593PheVal: 2.593 ± 0.427
0.519PheTrp: 0.519 ± 0.221
3.112PheTyr: 3.112 ± 0.615
0.0PheXaa: 0.0 ± 0.0
Gly
1.945GlyAla: 1.945 ± 0.694
0.648GlyCys: 0.648 ± 0.372
2.334GlyAsp: 2.334 ± 0.502
2.852GlyGlu: 2.852 ± 0.617
3.112GlyPhe: 3.112 ± 0.657
3.501GlyGly: 3.501 ± 1.327
0.778GlyHis: 0.778 ± 0.34
5.575GlyIle: 5.575 ± 1.034
4.408GlyLys: 4.408 ± 0.759
5.186GlyLeu: 5.186 ± 1.164
1.556GlyMet: 1.556 ± 0.426
2.982GlyAsn: 2.982 ± 0.558
0.648GlyPro: 0.648 ± 0.314
2.463GlyGln: 2.463 ± 0.649
1.297GlyArg: 1.297 ± 0.41
4.797GlySer: 4.797 ± 2.217
1.556GlyThr: 1.556 ± 0.43
3.371GlyVal: 3.371 ± 0.635
0.389GlyTrp: 0.389 ± 0.247
1.037GlyTyr: 1.037 ± 0.405
0.0GlyXaa: 0.0 ± 0.0
His
0.259HisAla: 0.259 ± 0.148
0.13HisCys: 0.13 ± 0.134
0.778HisAsp: 0.778 ± 0.343
0.648HisGlu: 0.648 ± 0.215
1.037HisPhe: 1.037 ± 0.462
0.389HisGly: 0.389 ± 0.241
0.13HisHis: 0.13 ± 0.125
0.259HisIle: 0.259 ± 0.234
2.074HisLys: 2.074 ± 0.633
1.167HisLeu: 1.167 ± 0.458
0.259HisMet: 0.259 ± 0.183
0.908HisAsn: 0.908 ± 0.344
0.519HisPro: 0.519 ± 0.27
0.0HisGln: 0.0 ± 0.0
1.297HisArg: 1.297 ± 0.359
0.648HisSer: 0.648 ± 0.326
0.778HisThr: 0.778 ± 0.355
0.778HisVal: 0.778 ± 0.299
0.389HisTrp: 0.389 ± 0.196
0.259HisTyr: 0.259 ± 0.198
0.0HisXaa: 0.0 ± 0.0
Ile
5.056IleAla: 5.056 ± 0.812
1.945IleCys: 1.945 ± 0.565
4.667IleAsp: 4.667 ± 0.876
5.316IleGlu: 5.316 ± 0.772
3.76IlePhe: 3.76 ± 0.692
5.445IleGly: 5.445 ± 0.881
1.426IleHis: 1.426 ± 0.404
8.427IleIle: 8.427 ± 0.989
5.445IleLys: 5.445 ± 1.03
8.946IleLeu: 8.946 ± 1.132
1.556IleMet: 1.556 ± 0.433
6.483IleAsn: 6.483 ± 0.941
3.241IlePro: 3.241 ± 0.63
2.852IleGln: 2.852 ± 0.68
2.852IleArg: 2.852 ± 0.545
4.667IleSer: 4.667 ± 0.935
4.797IleThr: 4.797 ± 0.805
5.445IleVal: 5.445 ± 0.886
0.0IleTrp: 0.0 ± 0.0
5.186IleTyr: 5.186 ± 0.856
0.0IleXaa: 0.0 ± 0.0
Lys
3.371LysAla: 3.371 ± 0.664
0.519LysCys: 0.519 ± 0.342
3.112LysAsp: 3.112 ± 0.542
7.52LysGlu: 7.52 ± 1.112
4.927LysPhe: 4.927 ± 0.741
4.408LysGly: 4.408 ± 0.799
1.426LysHis: 1.426 ± 0.462
7.39LysIle: 7.39 ± 1.381
5.705LysLys: 5.705 ± 0.721
5.964LysLeu: 5.964 ± 0.903
2.074LysMet: 2.074 ± 0.49
3.76LysAsn: 3.76 ± 0.635
2.593LysPro: 2.593 ± 0.644
4.019LysGln: 4.019 ± 0.739
2.982LysArg: 2.982 ± 0.627
3.501LysSer: 3.501 ± 0.756
3.76LysThr: 3.76 ± 0.734
5.056LysVal: 5.056 ± 0.807
0.908LysTrp: 0.908 ± 0.397
4.667LysTyr: 4.667 ± 0.77
0.0LysXaa: 0.0 ± 0.0
Leu
7.131LeuAla: 7.131 ± 1.022
1.167LeuCys: 1.167 ± 0.628
6.353LeuAsp: 6.353 ± 0.89
4.408LeuGlu: 4.408 ± 0.757
5.964LeuPhe: 5.964 ± 1.018
6.223LeuGly: 6.223 ± 1.169
1.037LeuHis: 1.037 ± 0.358
10.761LeuIle: 10.761 ± 1.373
8.038LeuLys: 8.038 ± 0.94
11.539LeuLeu: 11.539 ± 1.541
2.204LeuMet: 2.204 ± 0.436
6.483LeuAsn: 6.483 ± 0.841
4.278LeuPro: 4.278 ± 0.86
3.501LeuGln: 3.501 ± 0.651
4.538LeuArg: 4.538 ± 0.757
6.353LeuSer: 6.353 ± 0.913
6.223LeuThr: 6.223 ± 0.984
6.483LeuVal: 6.483 ± 0.952
0.259LeuTrp: 0.259 ± 0.196
3.89LeuTyr: 3.89 ± 0.643
0.0LeuXaa: 0.0 ± 0.0
Met
1.556MetAla: 1.556 ± 0.516
0.13MetCys: 0.13 ± 0.158
1.037MetAsp: 1.037 ± 0.435
1.685MetGlu: 1.685 ± 0.451
0.908MetPhe: 0.908 ± 0.336
1.037MetGly: 1.037 ± 0.331
0.0MetHis: 0.0 ± 0.0
3.241MetIle: 3.241 ± 0.613
2.074MetLys: 2.074 ± 0.513
1.685MetLeu: 1.685 ± 0.445
1.297MetMet: 1.297 ± 0.392
1.426MetAsn: 1.426 ± 0.581
0.519MetPro: 0.519 ± 0.247
0.389MetGln: 0.389 ± 0.223
1.167MetArg: 1.167 ± 0.459
2.463MetSer: 2.463 ± 0.411
1.426MetThr: 1.426 ± 0.415
0.908MetVal: 0.908 ± 0.335
0.0MetTrp: 0.0 ± 0.0
1.815MetTyr: 1.815 ± 0.51
0.0MetXaa: 0.0 ± 0.0
Asn
2.593AsnAla: 2.593 ± 0.591
0.648AsnCys: 0.648 ± 0.297
2.982AsnAsp: 2.982 ± 0.574
3.76AsnGlu: 3.76 ± 0.849
4.667AsnPhe: 4.667 ± 0.722
2.982AsnGly: 2.982 ± 0.602
0.389AsnHis: 0.389 ± 0.217
1.945AsnIle: 1.945 ± 0.545
3.76AsnLys: 3.76 ± 0.596
7.131AsnLeu: 7.131 ± 0.967
0.778AsnMet: 0.778 ± 0.315
3.371AsnAsn: 3.371 ± 1.018
3.371AsnPro: 3.371 ± 0.728
2.463AsnGln: 2.463 ± 0.621
1.556AsnArg: 1.556 ± 0.383
4.149AsnSer: 4.149 ± 0.74
3.501AsnThr: 3.501 ± 0.789
3.501AsnVal: 3.501 ± 0.779
0.389AsnTrp: 0.389 ± 0.228
4.278AsnTyr: 4.278 ± 0.767
0.0AsnXaa: 0.0 ± 0.0
Pro
2.074ProAla: 2.074 ± 0.617
0.389ProCys: 0.389 ± 0.229
2.204ProAsp: 2.204 ± 0.565
3.63ProGlu: 3.63 ± 0.878
2.463ProPhe: 2.463 ± 0.5
0.908ProGly: 0.908 ± 0.39
0.648ProHis: 0.648 ± 0.319
4.019ProIle: 4.019 ± 0.71
2.074ProLys: 2.074 ± 0.537
4.149ProLeu: 4.149 ± 0.754
0.389ProMet: 0.389 ± 0.221
2.074ProAsn: 2.074 ± 0.456
2.334ProPro: 2.334 ± 0.882
1.037ProGln: 1.037 ± 0.394
1.685ProArg: 1.685 ± 0.461
3.241ProSer: 3.241 ± 0.827
1.945ProThr: 1.945 ± 0.427
2.852ProVal: 2.852 ± 0.666
0.0ProTrp: 0.0 ± 0.0
1.815ProTyr: 1.815 ± 0.553
0.0ProXaa: 0.0 ± 0.0
Gln
1.556GlnAla: 1.556 ± 0.535
0.778GlnCys: 0.778 ± 0.413
1.037GlnAsp: 1.037 ± 0.332
2.982GlnGlu: 2.982 ± 0.831
1.556GlnPhe: 1.556 ± 0.415
1.037GlnGly: 1.037 ± 0.336
0.13GlnHis: 0.13 ± 0.117
3.241GlnIle: 3.241 ± 0.644
2.334GlnLys: 2.334 ± 0.606
4.797GlnLeu: 4.797 ± 1.005
0.778GlnMet: 0.778 ± 0.37
1.945GlnAsn: 1.945 ± 0.414
0.519GlnPro: 0.519 ± 0.253
2.204GlnGln: 2.204 ± 0.491
1.297GlnArg: 1.297 ± 0.399
1.815GlnSer: 1.815 ± 0.514
2.334GlnThr: 2.334 ± 0.458
1.945GlnVal: 1.945 ± 0.559
0.389GlnTrp: 0.389 ± 0.225
2.463GlnTyr: 2.463 ± 0.605
0.13GlnXaa: 0.13 ± 0.125
Arg
1.037ArgAla: 1.037 ± 0.337
0.0ArgCys: 0.0 ± 0.0
1.815ArgAsp: 1.815 ± 0.398
2.334ArgGlu: 2.334 ± 0.59
1.685ArgPhe: 1.685 ± 0.601
1.685ArgGly: 1.685 ± 0.438
0.519ArgHis: 0.519 ± 0.259
3.241ArgIle: 3.241 ± 0.726
3.241ArgLys: 3.241 ± 0.711
3.89ArgLeu: 3.89 ± 0.606
1.685ArgMet: 1.685 ± 0.59
1.815ArgAsn: 1.815 ± 0.499
0.648ArgPro: 0.648 ± 0.433
1.167ArgGln: 1.167 ± 0.493
1.167ArgArg: 1.167 ± 0.42
3.63ArgSer: 3.63 ± 0.524
1.945ArgThr: 1.945 ± 0.497
1.815ArgVal: 1.815 ± 0.475
0.259ArgTrp: 0.259 ± 0.168
2.074ArgTyr: 2.074 ± 0.482
0.0ArgXaa: 0.0 ± 0.0
Ser
1.945SerAla: 1.945 ± 0.476
0.908SerCys: 0.908 ± 0.451
2.982SerAsp: 2.982 ± 0.851
6.872SerGlu: 6.872 ± 1.728
3.241SerPhe: 3.241 ± 0.623
3.76SerGly: 3.76 ± 2.391
1.037SerHis: 1.037 ± 0.414
4.019SerIle: 4.019 ± 0.609
4.149SerLys: 4.149 ± 0.836
7.131SerLeu: 7.131 ± 1.149
2.982SerMet: 2.982 ± 0.685
3.63SerAsn: 3.63 ± 0.799
3.63SerPro: 3.63 ± 0.949
1.556SerGln: 1.556 ± 0.385
2.074SerArg: 2.074 ± 0.539
4.408SerSer: 4.408 ± 0.721
3.371SerThr: 3.371 ± 0.663
3.76SerVal: 3.76 ± 0.832
0.389SerTrp: 0.389 ± 0.185
3.501SerTyr: 3.501 ± 0.649
0.0SerXaa: 0.0 ± 0.0
Thr
2.852ThrAla: 2.852 ± 0.597
0.13ThrCys: 0.13 ± 0.117
3.241ThrAsp: 3.241 ± 0.666
1.556ThrGlu: 1.556 ± 0.397
3.76ThrPhe: 3.76 ± 0.761
2.334ThrGly: 2.334 ± 0.707
0.389ThrHis: 0.389 ± 0.178
4.797ThrIle: 4.797 ± 0.77
4.408ThrLys: 4.408 ± 0.654
5.056ThrLeu: 5.056 ± 0.787
1.685ThrMet: 1.685 ± 0.432
2.982ThrAsn: 2.982 ± 0.726
2.723ThrPro: 2.723 ± 0.572
2.852ThrGln: 2.852 ± 0.568
1.297ThrArg: 1.297 ± 0.524
2.982ThrSer: 2.982 ± 0.671
2.982ThrThr: 2.982 ± 0.863
1.945ThrVal: 1.945 ± 0.606
0.778ThrTrp: 0.778 ± 0.264
3.112ThrTyr: 3.112 ± 0.584
0.0ThrXaa: 0.0 ± 0.0
Val
1.297ValAla: 1.297 ± 0.307
0.519ValCys: 0.519 ± 0.242
2.593ValAsp: 2.593 ± 0.619
4.667ValGlu: 4.667 ± 1.045
3.76ValPhe: 3.76 ± 0.842
4.538ValGly: 4.538 ± 0.655
1.426ValHis: 1.426 ± 0.413
5.575ValIle: 5.575 ± 0.849
4.667ValLys: 4.667 ± 0.771
6.742ValLeu: 6.742 ± 0.966
1.426ValMet: 1.426 ± 0.503
1.945ValAsn: 1.945 ± 0.456
2.723ValPro: 2.723 ± 0.722
1.167ValGln: 1.167 ± 0.35
2.204ValArg: 2.204 ± 0.55
3.371ValSer: 3.371 ± 0.629
3.241ValThr: 3.241 ± 0.764
2.593ValVal: 2.593 ± 0.753
0.259ValTrp: 0.259 ± 0.194
4.927ValTyr: 4.927 ± 0.703
0.0ValXaa: 0.0 ± 0.0
Trp
0.259TrpAla: 0.259 ± 0.174
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.648TrpGlu: 0.648 ± 0.285
0.389TrpPhe: 0.389 ± 0.204
0.13TrpGly: 0.13 ± 0.127
0.0TrpHis: 0.0 ± 0.0
0.519TrpIle: 0.519 ± 0.384
0.519TrpLys: 0.519 ± 0.221
1.037TrpLeu: 1.037 ± 0.312
0.0TrpMet: 0.0 ± 0.0
0.519TrpAsn: 0.519 ± 0.254
0.0TrpPro: 0.0 ± 0.0
0.259TrpGln: 0.259 ± 0.18
0.13TrpArg: 0.13 ± 0.158
0.519TrpSer: 0.519 ± 0.262
0.259TrpThr: 0.259 ± 0.18
0.259TrpVal: 0.259 ± 0.2
0.0TrpTrp: 0.0 ± 0.0
0.778TrpTyr: 0.778 ± 0.303
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.501TyrAla: 3.501 ± 0.884
1.037TyrCys: 1.037 ± 0.381
3.63TyrAsp: 3.63 ± 0.588
3.241TyrGlu: 3.241 ± 0.756
1.945TyrPhe: 1.945 ± 0.398
2.723TyrGly: 2.723 ± 0.625
0.908TyrHis: 0.908 ± 0.383
4.667TyrIle: 4.667 ± 0.684
5.316TyrLys: 5.316 ± 1.025
5.705TyrLeu: 5.705 ± 0.812
0.648TyrMet: 0.648 ± 0.29
3.371TyrAsn: 3.371 ± 0.932
1.685TyrPro: 1.685 ± 0.595
1.815TyrGln: 1.815 ± 0.367
2.334TyrArg: 2.334 ± 0.471
3.89TyrSer: 3.89 ± 0.993
2.852TyrThr: 2.852 ± 0.739
4.408TyrVal: 4.408 ± 0.79
0.259TyrTrp: 0.259 ± 0.195
3.501TyrTyr: 3.501 ± 0.735
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.13XaaPhe: 0.13 ± 0.125
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 56 proteins (7714 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski