Amino acid dipepetide frequency for Salmonella phage g341c

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.926AlaAla: 8.926 ± 1.078
1.068AlaCys: 1.068 ± 0.271
6.637AlaAsp: 6.637 ± 0.883
6.256AlaGlu: 6.256 ± 0.665
3.357AlaPhe: 3.357 ± 0.452
6.79AlaGly: 6.79 ± 0.878
1.221AlaHis: 1.221 ± 0.335
5.188AlaIle: 5.188 ± 0.769
4.883AlaLys: 4.883 ± 0.659
5.645AlaLeu: 5.645 ± 0.677
3.28AlaMet: 3.28 ± 0.641
4.654AlaAsn: 4.654 ± 0.69
3.509AlaPro: 3.509 ± 0.633
3.357AlaGln: 3.357 ± 0.771
5.188AlaArg: 5.188 ± 0.591
5.951AlaSer: 5.951 ± 0.569
4.806AlaThr: 4.806 ± 0.82
5.34AlaVal: 5.34 ± 0.609
1.068AlaTrp: 1.068 ± 0.281
3.052AlaTyr: 3.052 ± 0.582
0.0AlaXaa: 0.0 ± 0.0
Cys
1.297CysAla: 1.297 ± 0.4
0.381CysCys: 0.381 ± 0.161
0.458CysAsp: 0.458 ± 0.204
0.839CysGlu: 0.839 ± 0.247
0.458CysPhe: 0.458 ± 0.193
1.678CysGly: 1.678 ± 0.362
0.534CysHis: 0.534 ± 0.244
0.687CysIle: 0.687 ± 0.243
0.915CysLys: 0.915 ± 0.266
0.915CysLeu: 0.915 ± 0.285
0.153CysMet: 0.153 ± 0.099
0.61CysAsn: 0.61 ± 0.242
0.229CysPro: 0.229 ± 0.122
0.305CysGln: 0.305 ± 0.122
1.221CysArg: 1.221 ± 0.314
0.61CysSer: 0.61 ± 0.225
0.458CysThr: 0.458 ± 0.185
0.992CysVal: 0.992 ± 0.318
0.229CysTrp: 0.229 ± 0.132
0.381CysTyr: 0.381 ± 0.17
0.0CysXaa: 0.0 ± 0.0
Asp
6.485AspAla: 6.485 ± 0.932
0.534AspCys: 0.534 ± 0.2
3.662AspAsp: 3.662 ± 0.588
3.662AspGlu: 3.662 ± 0.492
1.984AspPhe: 1.984 ± 0.326
5.035AspGly: 5.035 ± 0.716
0.915AspHis: 0.915 ± 0.278
3.967AspIle: 3.967 ± 0.42
2.746AspLys: 2.746 ± 0.425
4.959AspLeu: 4.959 ± 0.758
1.602AspMet: 1.602 ± 0.401
1.984AspAsn: 1.984 ± 0.395
1.755AspPro: 1.755 ± 0.443
1.221AspGln: 1.221 ± 0.27
2.212AspArg: 2.212 ± 0.459
3.433AspSer: 3.433 ± 0.506
1.526AspThr: 1.526 ± 0.393
4.806AspVal: 4.806 ± 0.604
0.763AspTrp: 0.763 ± 0.252
2.365AspTyr: 2.365 ± 0.374
0.0AspXaa: 0.0 ± 0.0
Glu
4.806GluAla: 4.806 ± 0.673
0.992GluCys: 0.992 ± 0.284
2.518GluAsp: 2.518 ± 0.427
3.814GluGlu: 3.814 ± 0.651
2.06GluPhe: 2.06 ± 0.405
3.509GluGly: 3.509 ± 0.508
1.297GluHis: 1.297 ± 0.281
4.654GluIle: 4.654 ± 0.681
3.662GluLys: 3.662 ± 0.52
6.561GluLeu: 6.561 ± 0.747
2.136GluMet: 2.136 ± 0.442
2.289GluAsn: 2.289 ± 0.423
1.984GluPro: 1.984 ± 0.35
4.501GluGln: 4.501 ± 0.518
3.967GluArg: 3.967 ± 0.544
3.204GluSer: 3.204 ± 0.452
3.204GluThr: 3.204 ± 0.541
4.12GluVal: 4.12 ± 0.724
1.831GluTrp: 1.831 ± 0.351
1.984GluTyr: 1.984 ± 0.446
0.0GluXaa: 0.0 ± 0.0
Phe
2.441PheAla: 2.441 ± 0.456
0.381PheCys: 0.381 ± 0.186
2.365PheAsp: 2.365 ± 0.412
2.136PheGlu: 2.136 ± 0.313
1.831PhePhe: 1.831 ± 0.36
2.518PheGly: 2.518 ± 0.343
0.61PheHis: 0.61 ± 0.238
2.823PheIle: 2.823 ± 0.48
2.67PheLys: 2.67 ± 0.379
1.984PheLeu: 1.984 ± 0.329
0.915PheMet: 0.915 ± 0.251
1.831PheAsn: 1.831 ± 0.305
1.602PhePro: 1.602 ± 0.302
1.373PheGln: 1.373 ± 0.396
2.136PheArg: 2.136 ± 0.538
3.967PheSer: 3.967 ± 0.45
2.136PheThr: 2.136 ± 0.361
2.136PheVal: 2.136 ± 0.374
0.915PheTrp: 0.915 ± 0.271
1.831PheTyr: 1.831 ± 0.389
0.0PheXaa: 0.0 ± 0.0
Gly
6.256GlyAla: 6.256 ± 0.882
0.915GlyCys: 0.915 ± 0.225
4.348GlyAsp: 4.348 ± 0.573
4.577GlyGlu: 4.577 ± 0.524
3.28GlyPhe: 3.28 ± 0.54
4.883GlyGly: 4.883 ± 0.725
1.602GlyHis: 1.602 ± 0.406
5.188GlyIle: 5.188 ± 0.723
4.806GlyLys: 4.806 ± 0.524
3.814GlyLeu: 3.814 ± 0.598
1.831GlyMet: 1.831 ± 0.465
3.509GlyAsn: 3.509 ± 0.52
1.297GlyPro: 1.297 ± 0.337
4.654GlyGln: 4.654 ± 0.743
4.959GlyArg: 4.959 ± 0.656
3.738GlySer: 3.738 ± 0.623
3.509GlyThr: 3.509 ± 0.536
5.645GlyVal: 5.645 ± 0.619
1.602GlyTrp: 1.602 ± 0.336
2.746GlyTyr: 2.746 ± 0.491
0.0GlyXaa: 0.0 ± 0.0
His
1.526HisAla: 1.526 ± 0.313
0.534HisCys: 0.534 ± 0.212
1.068HisAsp: 1.068 ± 0.304
1.373HisGlu: 1.373 ± 0.334
0.915HisPhe: 0.915 ± 0.283
1.831HisGly: 1.831 ± 0.375
0.61HisHis: 0.61 ± 0.188
0.381HisIle: 0.381 ± 0.169
1.373HisLys: 1.373 ± 0.345
1.984HisLeu: 1.984 ± 0.381
0.381HisMet: 0.381 ± 0.164
0.534HisAsn: 0.534 ± 0.189
0.915HisPro: 0.915 ± 0.286
0.839HisGln: 0.839 ± 0.262
1.144HisArg: 1.144 ± 0.308
1.068HisSer: 1.068 ± 0.277
0.458HisThr: 0.458 ± 0.165
1.068HisVal: 1.068 ± 0.272
0.305HisTrp: 0.305 ± 0.152
0.61HisTyr: 0.61 ± 0.205
0.0HisXaa: 0.0 ± 0.0
Ile
6.179IleAla: 6.179 ± 0.576
0.534IleCys: 0.534 ± 0.189
3.509IleAsp: 3.509 ± 0.437
3.357IleGlu: 3.357 ± 0.494
2.289IlePhe: 2.289 ± 0.498
4.501IleGly: 4.501 ± 0.637
1.373IleHis: 1.373 ± 0.259
4.196IleIle: 4.196 ± 0.74
3.357IleLys: 3.357 ± 0.661
3.662IleLeu: 3.662 ± 0.69
1.221IleMet: 1.221 ± 0.301
2.823IleAsn: 2.823 ± 0.556
2.975IlePro: 2.975 ± 0.459
2.67IleGln: 2.67 ± 0.439
3.357IleArg: 3.357 ± 0.482
4.577IleSer: 4.577 ± 0.634
3.738IleThr: 3.738 ± 0.522
2.746IleVal: 2.746 ± 0.399
0.763IleTrp: 0.763 ± 0.248
1.373IleTyr: 1.373 ± 0.42
0.0IleXaa: 0.0 ± 0.0
Lys
4.654LysAla: 4.654 ± 0.572
0.534LysCys: 0.534 ± 0.191
2.518LysAsp: 2.518 ± 0.415
4.73LysGlu: 4.73 ± 0.684
2.06LysPhe: 2.06 ± 0.388
4.501LysGly: 4.501 ± 0.639
1.144LysHis: 1.144 ± 0.311
2.899LysIle: 2.899 ± 0.562
4.12LysLys: 4.12 ± 0.622
4.806LysLeu: 4.806 ± 0.68
1.602LysMet: 1.602 ± 0.362
2.212LysAsn: 2.212 ± 0.403
3.128LysPro: 3.128 ± 0.524
3.662LysGln: 3.662 ± 0.497
3.509LysArg: 3.509 ± 0.498
4.654LysSer: 4.654 ± 0.544
2.975LysThr: 2.975 ± 0.564
3.128LysVal: 3.128 ± 0.628
0.534LysTrp: 0.534 ± 0.234
2.518LysTyr: 2.518 ± 0.499
0.0LysXaa: 0.0 ± 0.0
Leu
7.095LeuAla: 7.095 ± 0.831
1.373LeuCys: 1.373 ± 0.435
3.052LeuAsp: 3.052 ± 0.492
4.806LeuGlu: 4.806 ± 0.615
3.433LeuPhe: 3.433 ± 0.612
4.12LeuGly: 4.12 ± 0.735
1.373LeuHis: 1.373 ± 0.275
3.662LeuIle: 3.662 ± 0.559
4.577LeuLys: 4.577 ± 0.587
6.103LeuLeu: 6.103 ± 0.835
2.136LeuMet: 2.136 ± 0.36
4.425LeuAsn: 4.425 ± 0.607
3.662LeuPro: 3.662 ± 0.425
2.975LeuGln: 2.975 ± 0.503
5.569LeuArg: 5.569 ± 0.898
5.569LeuSer: 5.569 ± 0.644
4.806LeuThr: 4.806 ± 0.41
3.967LeuVal: 3.967 ± 0.456
1.373LeuTrp: 1.373 ± 0.345
2.289LeuTyr: 2.289 ± 0.431
0.0LeuXaa: 0.0 ± 0.0
Met
3.814MetAla: 3.814 ± 0.467
0.229MetCys: 0.229 ± 0.135
1.449MetAsp: 1.449 ± 0.307
1.373MetGlu: 1.373 ± 0.269
0.763MetPhe: 0.763 ± 0.213
1.907MetGly: 1.907 ± 0.378
0.534MetHis: 0.534 ± 0.212
1.144MetIle: 1.144 ± 0.309
2.06MetLys: 2.06 ± 0.416
2.594MetLeu: 2.594 ± 0.404
0.763MetMet: 0.763 ± 0.269
1.221MetAsn: 1.221 ± 0.274
1.602MetPro: 1.602 ± 0.269
1.221MetGln: 1.221 ± 0.387
2.212MetArg: 2.212 ± 0.449
1.831MetSer: 1.831 ± 0.323
1.526MetThr: 1.526 ± 0.291
0.839MetVal: 0.839 ± 0.269
0.076MetTrp: 0.076 ± 0.074
1.221MetTyr: 1.221 ± 0.298
0.0MetXaa: 0.0 ± 0.0
Asn
4.883AsnAla: 4.883 ± 0.641
0.305AsnCys: 0.305 ± 0.169
2.365AsnAsp: 2.365 ± 0.393
2.899AsnGlu: 2.899 ± 0.402
0.839AsnPhe: 0.839 ± 0.212
4.12AsnGly: 4.12 ± 0.641
1.297AsnHis: 1.297 ± 0.324
2.67AsnIle: 2.67 ± 0.458
2.67AsnLys: 2.67 ± 0.433
3.433AsnLeu: 3.433 ± 0.559
1.068AsnMet: 1.068 ± 0.301
2.518AsnAsn: 2.518 ± 0.416
3.128AsnPro: 3.128 ± 0.483
2.746AsnGln: 2.746 ± 0.525
1.984AsnArg: 1.984 ± 0.358
2.823AsnSer: 2.823 ± 0.466
2.06AsnThr: 2.06 ± 0.418
2.212AsnVal: 2.212 ± 0.5
0.687AsnTrp: 0.687 ± 0.235
1.755AsnTyr: 1.755 ± 0.423
0.0AsnXaa: 0.0 ± 0.0
Pro
3.204ProAla: 3.204 ± 0.44
0.61ProCys: 0.61 ± 0.211
3.128ProAsp: 3.128 ± 0.449
4.73ProGlu: 4.73 ± 0.658
1.831ProPhe: 1.831 ± 0.384
2.06ProGly: 2.06 ± 0.317
0.534ProHis: 0.534 ± 0.194
2.365ProIle: 2.365 ± 0.385
2.899ProLys: 2.899 ± 0.44
2.136ProLeu: 2.136 ± 0.378
0.915ProMet: 0.915 ± 0.29
1.678ProAsn: 1.678 ± 0.324
1.984ProPro: 1.984 ± 0.383
1.755ProGln: 1.755 ± 0.46
1.755ProArg: 1.755 ± 0.423
3.662ProSer: 3.662 ± 0.491
2.06ProThr: 2.06 ± 0.367
3.586ProVal: 3.586 ± 0.496
0.381ProTrp: 0.381 ± 0.14
1.449ProTyr: 1.449 ± 0.338
0.0ProXaa: 0.0 ± 0.0
Gln
4.425GlnAla: 4.425 ± 0.948
0.534GlnCys: 0.534 ± 0.251
2.823GlnAsp: 2.823 ± 0.508
2.136GlnGlu: 2.136 ± 0.439
1.831GlnPhe: 1.831 ± 0.306
2.823GlnGly: 2.823 ± 0.555
0.763GlnHis: 0.763 ± 0.235
3.128GlnIle: 3.128 ± 0.394
2.212GlnLys: 2.212 ± 0.349
4.12GlnLeu: 4.12 ± 0.628
1.678GlnMet: 1.678 ± 0.342
2.899GlnAsn: 2.899 ± 0.614
2.06GlnPro: 2.06 ± 0.35
3.586GlnGln: 3.586 ± 0.691
2.289GlnArg: 2.289 ± 0.448
3.433GlnSer: 3.433 ± 0.453
1.526GlnThr: 1.526 ± 0.399
2.518GlnVal: 2.518 ± 0.457
0.992GlnTrp: 0.992 ± 0.234
2.441GlnTyr: 2.441 ± 0.414
0.0GlnXaa: 0.0 ± 0.0
Arg
4.73ArgAla: 4.73 ± 0.586
1.373ArgCys: 1.373 ± 0.356
3.662ArgAsp: 3.662 ± 0.676
3.738ArgGlu: 3.738 ± 0.741
2.06ArgPhe: 2.06 ± 0.38
3.891ArgGly: 3.891 ± 0.707
1.449ArgHis: 1.449 ± 0.328
3.738ArgIle: 3.738 ± 0.43
3.891ArgLys: 3.891 ± 0.754
5.417ArgLeu: 5.417 ± 0.578
2.441ArgMet: 2.441 ± 0.415
2.899ArgAsn: 2.899 ± 0.304
1.755ArgPro: 1.755 ± 0.294
2.67ArgGln: 2.67 ± 0.46
2.823ArgArg: 2.823 ± 0.643
3.586ArgSer: 3.586 ± 0.462
2.594ArgThr: 2.594 ± 0.414
3.128ArgVal: 3.128 ± 0.527
0.534ArgTrp: 0.534 ± 0.186
2.212ArgTyr: 2.212 ± 0.488
0.0ArgXaa: 0.0 ± 0.0
Ser
5.34SerAla: 5.34 ± 0.859
0.381SerCys: 0.381 ± 0.156
3.586SerAsp: 3.586 ± 0.687
4.12SerGlu: 4.12 ± 0.515
2.899SerPhe: 2.899 ± 0.497
5.951SerGly: 5.951 ± 0.645
1.373SerHis: 1.373 ± 0.425
3.509SerIle: 3.509 ± 0.525
3.738SerLys: 3.738 ± 0.55
5.798SerLeu: 5.798 ± 0.753
2.518SerMet: 2.518 ± 0.376
2.365SerAsn: 2.365 ± 0.433
3.586SerPro: 3.586 ± 0.564
3.204SerGln: 3.204 ± 0.513
4.043SerArg: 4.043 ± 0.541
4.272SerSer: 4.272 ± 0.768
2.518SerThr: 2.518 ± 0.448
3.662SerVal: 3.662 ± 0.528
0.915SerTrp: 0.915 ± 0.281
2.823SerTyr: 2.823 ± 0.537
0.0SerXaa: 0.0 ± 0.0
Thr
4.806ThrAla: 4.806 ± 0.64
0.61ThrCys: 0.61 ± 0.215
2.67ThrAsp: 2.67 ± 0.435
2.06ThrGlu: 2.06 ± 0.435
1.526ThrPhe: 1.526 ± 0.47
5.645ThrGly: 5.645 ± 0.68
0.763ThrHis: 0.763 ± 0.196
3.357ThrIle: 3.357 ± 0.522
3.433ThrLys: 3.433 ± 0.467
3.28ThrLeu: 3.28 ± 0.459
1.144ThrMet: 1.144 ± 0.311
1.831ThrAsn: 1.831 ± 0.393
2.823ThrPro: 2.823 ± 0.603
2.441ThrGln: 2.441 ± 0.312
2.441ThrArg: 2.441 ± 0.377
3.128ThrSer: 3.128 ± 0.425
2.899ThrThr: 2.899 ± 0.54
2.746ThrVal: 2.746 ± 0.394
0.458ThrTrp: 0.458 ± 0.215
1.297ThrTyr: 1.297 ± 0.222
0.0ThrXaa: 0.0 ± 0.0
Val
4.959ValAla: 4.959 ± 0.613
0.992ValCys: 0.992 ± 0.294
2.594ValAsp: 2.594 ± 0.346
3.967ValGlu: 3.967 ± 0.472
2.594ValPhe: 2.594 ± 0.482
4.12ValGly: 4.12 ± 0.602
0.229ValHis: 0.229 ± 0.146
3.662ValIle: 3.662 ± 0.646
2.823ValLys: 2.823 ± 0.393
3.967ValLeu: 3.967 ± 0.516
1.602ValMet: 1.602 ± 0.376
3.509ValAsn: 3.509 ± 0.503
2.441ValPro: 2.441 ± 0.46
2.365ValGln: 2.365 ± 0.451
3.204ValArg: 3.204 ± 0.407
4.043ValSer: 4.043 ± 0.548
4.501ValThr: 4.501 ± 0.552
4.196ValVal: 4.196 ± 0.515
1.297ValTrp: 1.297 ± 0.319
2.594ValTyr: 2.594 ± 0.599
0.0ValXaa: 0.0 ± 0.0
Trp
1.144TrpAla: 1.144 ± 0.281
0.305TrpCys: 0.305 ± 0.158
0.992TrpAsp: 0.992 ± 0.254
0.61TrpGlu: 0.61 ± 0.227
0.687TrpPhe: 0.687 ± 0.205
0.839TrpGly: 0.839 ± 0.217
0.687TrpHis: 0.687 ± 0.268
0.458TrpIle: 0.458 ± 0.169
0.992TrpLys: 0.992 ± 0.31
1.526TrpLeu: 1.526 ± 0.331
0.229TrpMet: 0.229 ± 0.114
0.839TrpAsn: 0.839 ± 0.25
0.839TrpPro: 0.839 ± 0.229
0.992TrpGln: 0.992 ± 0.289
1.297TrpArg: 1.297 ± 0.336
1.068TrpSer: 1.068 ± 0.359
0.381TrpThr: 0.381 ± 0.141
0.687TrpVal: 0.687 ± 0.226
0.458TrpTrp: 0.458 ± 0.178
0.381TrpTyr: 0.381 ± 0.185
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.204TyrAla: 3.204 ± 0.441
0.763TyrCys: 0.763 ± 0.246
2.212TyrAsp: 2.212 ± 0.472
1.907TyrGlu: 1.907 ± 0.446
1.907TyrPhe: 1.907 ± 0.386
2.441TyrGly: 2.441 ± 0.464
0.61TyrHis: 0.61 ± 0.221
1.526TyrIle: 1.526 ± 0.426
2.06TyrLys: 2.06 ± 0.404
3.662TyrLeu: 3.662 ± 0.565
0.687TyrMet: 0.687 ± 0.208
1.831TyrAsn: 1.831 ± 0.413
1.449TyrPro: 1.449 ± 0.374
1.678TyrGln: 1.678 ± 0.369
3.28TyrArg: 3.28 ± 0.511
2.06TyrSer: 2.06 ± 0.408
1.678TyrThr: 1.678 ± 0.31
2.136TyrVal: 2.136 ± 0.353
0.229TyrTrp: 0.229 ± 0.138
0.915TyrTyr: 0.915 ± 0.286
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 68 proteins (13109 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski