Amino acid dipepetide frequency for Chitinimonas taiwanensis DSM 18899

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.434AlaAla: 17.434 ± 0.208	1.28AlaCys: 1.28 ± 0.033	6.761AlaAsp: 6.761 ± 0.084	8.248AlaGlu: 8.248 ± 0.113	3.869AlaPhe: 3.869 ± 0.056	10.557AlaGly: 10.557 ± 0.121	2.567AlaHis: 2.567 ± 0.055	5.415AlaIle: 5.415 ± 0.074	4.434AlaLys: 4.434 ± 0.082	15.776AlaLeu: 15.776 ± 0.143	3.219AlaMet: 3.219 ± 0.06	3.278AlaAsn: 3.278 ± 0.065	5.443AlaPro: 5.443 ± 0.088	6.344AlaGln: 6.344 ± 0.089	8.527AlaArg: 8.527 ± 0.103	7.218AlaSer: 7.218 ± 0.095	5.022AlaThr: 5.022 ± 0.068	7.915AlaVal: 7.915 ± 0.085	1.875AlaTrp: 1.875 ± 0.04	2.813AlaTyr: 2.813 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.137CysAla: 1.137 ± 0.029	0.125CysCys: 0.125 ± 0.01	0.491CysAsp: 0.491 ± 0.022	0.434CysGlu: 0.434 ± 0.019	0.335CysPhe: 0.335 ± 0.017	0.863CysGly: 0.863 ± 0.032	0.274CysHis: 0.274 ± 0.017	0.324CysIle: 0.324 ± 0.019	0.247CysLys: 0.247 ± 0.013	1.06CysLeu: 1.06 ± 0.031	0.187CysMet: 0.187 ± 0.013	0.235CysAsn: 0.235 ± 0.014	0.495CysPro: 0.495 ± 0.022	0.37CysGln: 0.37 ± 0.018	0.606CysArg: 0.606 ± 0.023	0.48CysSer: 0.48 ± 0.022	0.409CysThr: 0.409 ± 0.021	0.599CysVal: 0.599 ± 0.023	0.146CysTrp: 0.146 ± 0.011	0.229CysTyr: 0.229 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.825AspAla: 6.825 ± 0.084	0.525AspCys: 0.525 ± 0.024	2.387AspAsp: 2.387 ± 0.044	3.228AspGlu: 3.228 ± 0.066	2.271AspPhe: 2.271 ± 0.047	4.563AspGly: 4.563 ± 0.067	0.938AspHis: 0.938 ± 0.028	2.605AspIle: 2.605 ± 0.053	2.183AspLys: 2.183 ± 0.05	5.318AspLeu: 5.318 ± 0.077	1.143AspMet: 1.143 ± 0.032	1.318AspAsn: 1.318 ± 0.035	2.58AspPro: 2.58 ± 0.046	1.716AspGln: 1.716 ± 0.038	2.681AspArg: 2.681 ± 0.054	2.806AspSer: 2.806 ± 0.05	2.385AspThr: 2.385 ± 0.047	3.322AspVal: 3.322 ± 0.053	1.198AspTrp: 1.198 ± 0.029	1.733AspTyr: 1.733 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	7.755GluAla: 7.755 ± 0.103	0.374GluCys: 0.374 ± 0.019	2.316GluAsp: 2.316 ± 0.043	2.605GluGlu: 2.605 ± 0.053	1.699GluPhe: 1.699 ± 0.04	3.584GluGly: 3.584 ± 0.056	1.397GluHis: 1.397 ± 0.037	2.917GluIle: 2.917 ± 0.059	1.952GluLys: 1.952 ± 0.045	6.823GluLeu: 6.823 ± 0.1	1.297GluMet: 1.297 ± 0.037	1.403GluAsn: 1.403 ± 0.035	2.314GluPro: 2.314 ± 0.041	3.428GluGln: 3.428 ± 0.057	4.547GluArg: 4.547 ± 0.065	2.465GluSer: 2.465 ± 0.049	2.403GluThr: 2.403 ± 0.046	4.004GluVal: 4.004 ± 0.067	0.708GluTrp: 0.708 ± 0.025	1.229GluTyr: 1.229 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.233PheAla: 4.233 ± 0.066	0.438PheCys: 0.438 ± 0.02	2.529PheAsp: 2.529 ± 0.051	2.124PheGlu: 2.124 ± 0.045	1.302PhePhe: 1.302 ± 0.036	3.261PheGly: 3.261 ± 0.06	0.762PheHis: 0.762 ± 0.024	1.581PheIle: 1.581 ± 0.034	1.307PheLys: 1.307 ± 0.034	3.235PheLeu: 3.235 ± 0.054	0.765PheMet: 0.765 ± 0.027	1.163PheAsn: 1.163 ± 0.036	1.429PhePro: 1.429 ± 0.039	1.227PheGln: 1.227 ± 0.029	1.856PheArg: 1.856 ± 0.04	2.39PheSer: 2.39 ± 0.053	1.664PheThr: 1.664 ± 0.043	2.454PheVal: 2.454 ± 0.046	0.555PheTrp: 0.555 ± 0.022	1.005PheTyr: 1.005 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	7.723GlyAla: 7.723 ± 0.114	0.789GlyCys: 0.789 ± 0.024	3.806GlyAsp: 3.806 ± 0.051	4.928GlyGlu: 4.928 ± 0.068	3.294GlyPhe: 3.294 ± 0.05	6.158GlyGly: 6.158 ± 0.093	1.716GlyHis: 1.716 ± 0.04	3.749GlyIle: 3.749 ± 0.058	3.624GlyLys: 3.624 ± 0.067	9.393GlyLeu: 9.393 ± 0.102	2.167GlyMet: 2.167 ± 0.044	2.185GlyAsn: 2.185 ± 0.051	2.535GlyPro: 2.535 ± 0.047	3.991GlyGln: 3.991 ± 0.058	5.191GlyArg: 5.191 ± 0.073	4.609GlySer: 4.609 ± 0.082	3.34GlyThr: 3.34 ± 0.061	5.842GlyVal: 5.842 ± 0.072	1.418GlyTrp: 1.418 ± 0.041	2.331GlyTyr: 2.331 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.846HisAla: 2.846 ± 0.056	0.262HisCys: 0.262 ± 0.015	1.209HisAsp: 1.209 ± 0.034	1.092HisGlu: 1.092 ± 0.03	0.992HisPhe: 0.992 ± 0.03	2.086HisGly: 2.086 ± 0.048	0.572HisHis: 0.572 ± 0.022	1.068HisIle: 1.068 ± 0.034	0.629HisLys: 0.629 ± 0.021	2.293HisLeu: 2.293 ± 0.045	0.428HisMet: 0.428 ± 0.021	0.536HisAsn: 0.536 ± 0.02	1.358HisPro: 1.358 ± 0.033	0.803HisGln: 0.803 ± 0.024	1.228HisArg: 1.228 ± 0.035	1.198HisSer: 1.198 ± 0.036	1.038HisThr: 1.038 ± 0.03	1.207HisVal: 1.207 ± 0.034	0.473HisTrp: 0.473 ± 0.02	0.815HisTyr: 0.815 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.121IleAla: 6.121 ± 0.072	0.443IleCys: 0.443 ± 0.02	3.055IleAsp: 3.055 ± 0.047	3.159IleGlu: 3.159 ± 0.05	1.242IlePhe: 1.242 ± 0.032	4.065IleGly: 4.065 ± 0.057	0.915IleHis: 0.915 ± 0.027	1.631IleIle: 1.631 ± 0.043	1.727IleLys: 1.727 ± 0.036	3.773IleLeu: 3.773 ± 0.057	0.71IleMet: 0.71 ± 0.026	1.469IleAsn: 1.469 ± 0.034	2.017IlePro: 2.017 ± 0.045	1.51IleGln: 1.51 ± 0.04	2.693IleArg: 2.693 ± 0.049	2.784IleSer: 2.784 ± 0.053	2.213IleThr: 2.213 ± 0.045	3.317IleVal: 3.317 ± 0.058	0.559IleTrp: 0.559 ± 0.022	1.097IleTyr: 1.097 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.106LysAla: 4.106 ± 0.074	0.179LysCys: 0.179 ± 0.011	1.57LysAsp: 1.57 ± 0.043	1.54LysGlu: 1.54 ± 0.04	0.965LysPhe: 0.965 ± 0.03	2.328LysGly: 2.328 ± 0.048	0.815LysHis: 0.815 ± 0.027	1.576LysIle: 1.576 ± 0.043	1.44LysLys: 1.44 ± 0.045	4.784LysLeu: 4.784 ± 0.076	0.802LysMet: 0.802 ± 0.029	0.952LysAsn: 0.952 ± 0.031	2.542LysPro: 2.542 ± 0.06	1.939LysGln: 1.939 ± 0.045	2.378LysArg: 2.378 ± 0.045	1.763LysSer: 1.763 ± 0.037	1.876LysThr: 1.876 ± 0.045	2.491LysVal: 2.491 ± 0.055	0.373LysTrp: 0.373 ± 0.02	0.745LysTyr: 0.745 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	17.744LeuAla: 17.744 ± 0.171	1.188LeuCys: 1.188 ± 0.032	6.595LeuAsp: 6.595 ± 0.092	5.416LeuGlu: 5.416 ± 0.079	3.921LeuPhe: 3.921 ± 0.056	9.255LeuGly: 9.255 ± 0.119	2.584LeuHis: 2.584 ± 0.05	5.286LeuIle: 5.286 ± 0.072	4.243LeuLys: 4.243 ± 0.064	14.157LeuLeu: 14.157 ± 0.172	2.332LeuMet: 2.332 ± 0.043	3.562LeuAsn: 3.562 ± 0.058	7.033LeuPro: 7.033 ± 0.089	5.054LeuGln: 5.054 ± 0.073	8.031LeuArg: 8.031 ± 0.099	7.59LeuSer: 7.59 ± 0.1	4.977LeuThr: 4.977 ± 0.082	7.041LeuVal: 7.041 ± 0.085	1.414LeuTrp: 1.414 ± 0.037	2.479LeuTyr: 2.479 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.714MetAla: 2.714 ± 0.049	0.13MetCys: 0.13 ± 0.01	0.968MetAsp: 0.968 ± 0.029	0.92MetGlu: 0.92 ± 0.026	0.634MetPhe: 0.634 ± 0.021	1.54MetGly: 1.54 ± 0.043	0.533MetHis: 0.533 ± 0.025	0.829MetIle: 0.829 ± 0.03	0.866MetLys: 0.866 ± 0.029	2.786MetLeu: 2.786 ± 0.046	0.438MetMet: 0.438 ± 0.019	0.741MetAsn: 0.741 ± 0.025	1.371MetPro: 1.371 ± 0.035	1.297MetGln: 1.297 ± 0.041	1.578MetArg: 1.578 ± 0.039	1.655MetSer: 1.655 ± 0.037	1.081MetThr: 1.081 ± 0.035	1.37MetVal: 1.37 ± 0.039	0.176MetTrp: 0.176 ± 0.012	0.36MetTyr: 0.36 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.189AsnAla: 3.189 ± 0.054	0.263AsnCys: 0.263 ± 0.015	1.364AsnAsp: 1.364 ± 0.04	1.387AsnGlu: 1.387 ± 0.037	0.963AsnPhe: 0.963 ± 0.028	2.399AsnGly: 2.399 ± 0.051	0.572AsnHis: 0.572 ± 0.021	1.256AsnIle: 1.256 ± 0.036	0.957AsnLys: 0.957 ± 0.031	3.182AsnLeu: 3.182 ± 0.055	0.579AsnMet: 0.579 ± 0.022	0.773AsnAsn: 0.773 ± 0.031	1.885AsnPro: 1.885 ± 0.04	1.17AsnGln: 1.17 ± 0.034	1.762AsnArg: 1.762 ± 0.043	1.37AsnSer: 1.37 ± 0.037	1.439AsnThr: 1.439 ± 0.04	1.802AsnVal: 1.802 ± 0.038	0.478AsnTrp: 0.478 ± 0.02	0.786AsnTyr: 0.786 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	7.287ProAla: 7.287 ± 0.104	0.35ProCys: 0.35 ± 0.016	2.968ProAsp: 2.968 ± 0.048	3.159ProGlu: 3.159 ± 0.052	1.706ProPhe: 1.706 ± 0.037	3.726ProGly: 3.726 ± 0.062	1.073ProHis: 1.073 ± 0.033	1.978ProIle: 1.978 ± 0.042	1.669ProLys: 1.669 ± 0.042	5.627ProLeu: 5.627 ± 0.071	1.089ProMet: 1.089 ± 0.029	1.428ProAsn: 1.428 ± 0.037	2.29ProPro: 2.29 ± 0.059	2.028ProGln: 2.028 ± 0.045	2.605ProArg: 2.605 ± 0.055	2.931ProSer: 2.931 ± 0.057	2.277ProThr: 2.277 ± 0.065	3.577ProVal: 3.577 ± 0.06	0.745ProTrp: 0.745 ± 0.022	1.294ProTyr: 1.294 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	6.875GlnAla: 6.875 ± 0.105	0.281GlnCys: 0.281 ± 0.014	1.895GlnAsp: 1.895 ± 0.044	1.678GlnGlu: 1.678 ± 0.037	1.503GlnPhe: 1.503 ± 0.035	3.482GlnGly: 3.482 ± 0.064	1.285GlnHis: 1.285 ± 0.034	2.264GlnIle: 2.264 ± 0.046	1.218GlnLys: 1.218 ± 0.036	6.239GlnLeu: 6.239 ± 0.084	0.954GlnMet: 0.954 ± 0.024	1.0GlnAsn: 1.0 ± 0.029	2.723GlnPro: 2.723 ± 0.05	2.717GlnGln: 2.717 ± 0.061	3.728GlnArg: 3.728 ± 0.058	2.209GlnSer: 2.209 ± 0.044	2.146GlnThr: 2.146 ± 0.046	2.99GlnVal: 2.99 ± 0.053	0.621GlnTrp: 0.621 ± 0.023	1.009GlnTyr: 1.009 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	7.465ArgAla: 7.465 ± 0.083	0.543ArgCys: 0.543 ± 0.021	3.516ArgAsp: 3.516 ± 0.067	4.258ArgGlu: 4.258 ± 0.081	2.909ArgPhe: 2.909 ± 0.046	4.171ArgGly: 4.171 ± 0.059	1.72ArgHis: 1.72 ± 0.037	3.223ArgIle: 3.223 ± 0.055	2.043ArgLys: 2.043 ± 0.043	8.235ArgLeu: 8.235 ± 0.091	1.54ArgMet: 1.54 ± 0.038	1.769ArgAsn: 1.769 ± 0.037	2.853ArgPro: 2.853 ± 0.047	3.464ArgGln: 3.464 ± 0.063	4.332ArgArg: 4.332 ± 0.065	3.396ArgSer: 3.396 ± 0.057	2.506ArgThr: 2.506 ± 0.045	4.38ArgVal: 4.38 ± 0.059	1.165ArgTrp: 1.165 ± 0.033	2.147ArgTyr: 2.147 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.834SerAla: 6.834 ± 0.091	0.492SerCys: 0.492 ± 0.023	2.664SerAsp: 2.664 ± 0.052	3.07SerGlu: 3.07 ± 0.051	2.141SerPhe: 2.141 ± 0.047	5.106SerGly: 5.106 ± 0.092	1.193SerHis: 1.193 ± 0.031	2.326SerIle: 2.326 ± 0.045	1.961SerLys: 1.961 ± 0.046	6.96SerLeu: 6.96 ± 0.09	1.232SerMet: 1.232 ± 0.032	1.567SerAsn: 1.567 ± 0.039	2.751SerPro: 2.751 ± 0.05	2.537SerGln: 2.537 ± 0.056	3.41SerArg: 3.41 ± 0.058	3.385SerSer: 3.385 ± 0.081	2.76SerThr: 2.76 ± 0.057	3.699SerVal: 3.699 ± 0.062	0.939SerTrp: 0.939 ± 0.025	1.581SerTyr: 1.581 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.082ThrAla: 5.082 ± 0.075	0.292ThrCys: 0.292 ± 0.019	2.038ThrAsp: 2.038 ± 0.044	2.32ThrGlu: 2.32 ± 0.043	1.42ThrPhe: 1.42 ± 0.044	3.672ThrGly: 3.672 ± 0.06	0.935ThrHis: 0.935 ± 0.032	1.981ThrIle: 1.981 ± 0.048	1.079ThrLys: 1.079 ± 0.032	6.284ThrLeu: 6.284 ± 0.083	0.817ThrMet: 0.817 ± 0.025	1.034ThrAsn: 1.034 ± 0.033	3.047ThrPro: 3.047 ± 0.058	1.92ThrGln: 1.92 ± 0.04	2.858ThrArg: 2.858 ± 0.044	2.242ThrSer: 2.242 ± 0.047	2.088ThrThr: 2.088 ± 0.046	3.773ThrVal: 3.773 ± 0.049	0.473ThrTrp: 0.473 ± 0.023	0.946ThrTyr: 0.946 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	8.264ValAla: 8.264 ± 0.09	0.665ValCys: 0.665 ± 0.027	3.694ValAsp: 3.694 ± 0.061	3.929ValGlu: 3.929 ± 0.067	2.515ValPhe: 2.515 ± 0.05	5.016ValGly: 5.016 ± 0.074	1.307ValHis: 1.307 ± 0.031	3.053ValIle: 3.053 ± 0.052	2.423ValLys: 2.423 ± 0.046	8.266ValLeu: 8.266 ± 0.102	1.546ValMet: 1.546 ± 0.037	2.105ValAsn: 2.105 ± 0.044	3.084ValPro: 3.084 ± 0.06	2.762ValGln: 2.762 ± 0.054	4.308ValArg: 4.308 ± 0.061	4.085ValSer: 4.085 ± 0.072	2.897ValThr: 2.897 ± 0.05	5.048ValVal: 5.048 ± 0.074	0.909ValTrp: 0.909 ± 0.032	1.539ValTyr: 1.539 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.32TrpAla: 1.32 ± 0.039	0.157TrpCys: 0.157 ± 0.012	0.631TrpAsp: 0.631 ± 0.023	0.519TrpGlu: 0.519 ± 0.022	0.573TrpPhe: 0.573 ± 0.022	0.907TrpGly: 0.907 ± 0.034	0.425TrpHis: 0.425 ± 0.016	0.548TrpIle: 0.548 ± 0.019	0.395TrpLys: 0.395 ± 0.021	2.646TrpLeu: 2.646 ± 0.056	0.352TrpMet: 0.352 ± 0.015	0.378TrpAsn: 0.378 ± 0.017	0.748TrpPro: 0.748 ± 0.031	1.221TrpGln: 1.221 ± 0.034	1.327TrpArg: 1.327 ± 0.037	0.698TrpSer: 0.698 ± 0.027	0.555TrpThr: 0.555 ± 0.024	0.935TrpVal: 0.935 ± 0.027	0.302TrpTrp: 0.302 ± 0.015	0.32TrpTyr: 0.32 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.043TyrAla: 3.043 ± 0.05	0.27TyrCys: 0.27 ± 0.015	1.268TyrAsp: 1.268 ± 0.029	1.205TyrGlu: 1.205 ± 0.032	1.025TyrPhe: 1.025 ± 0.03	2.05TyrGly: 2.05 ± 0.048	0.55TyrHis: 0.55 ± 0.023	0.892TyrIle: 0.892 ± 0.03	0.767TyrLys: 0.767 ± 0.028	3.062TyrLeu: 3.062 ± 0.045	0.39TyrMet: 0.39 ± 0.018	0.68TyrAsn: 0.68 ± 0.025	1.31TyrPro: 1.31 ± 0.031	1.316TyrGln: 1.316 ± 0.034	1.989TyrArg: 1.989 ± 0.045	1.335TyrSer: 1.335 ± 0.038	1.226TyrThr: 1.226 ± 0.031	1.648TyrVal: 1.648 ± 0.036	0.431TyrTrp: 0.431 ± 0.021	0.689TyrTyr: 0.689 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3699 proteins (1215398 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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