Amino acid dipepetide frequency for Penaeid shrimp infectious myonecrosis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.435AlaAla: 5.435 ± 0.88
0.604AlaCys: 0.604 ± 0.372
1.812AlaAsp: 1.812 ± 1.117
3.019AlaGlu: 3.019 ± 0.214
1.208AlaPhe: 1.208 ± 0.745
5.435AlaGly: 5.435 ± 1.703
1.208AlaHis: 1.208 ± 0.745
5.435AlaIle: 5.435 ± 1.591
3.623AlaLys: 3.623 ± 1.061
3.623AlaLeu: 3.623 ± 1.41
3.623AlaMet: 3.623 ± 2.234
5.435AlaAsn: 5.435 ± 2.527
2.415AlaPro: 2.415 ± 1.489
2.415AlaGln: 2.415 ± 0.665
4.227AlaArg: 4.227 ± 1.782
3.623AlaSer: 3.623 ± 0.237
4.227AlaThr: 4.227 ± 1.782
4.227AlaVal: 4.227 ± 0.135
1.812AlaTrp: 1.812 ± 0.293
3.623AlaTyr: 3.623 ± 0.586
0.0AlaXaa: 0.0 ± 0.0
Cys
0.604CysAla: 0.604 ± 0.372
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.208CysGlu: 1.208 ± 0.903
0.0CysPhe: 0.0 ± 0.0
1.208CysGly: 1.208 ± 0.745
0.0CysHis: 0.0 ± 0.0
1.208CysIle: 1.208 ± 0.079
0.604CysLys: 0.604 ± 0.451
0.604CysLeu: 0.604 ± 0.372
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.604CysGln: 0.604 ± 0.372
0.604CysArg: 0.604 ± 0.451
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.019AspAla: 3.019 ± 1.038
0.0AspCys: 0.0 ± 0.0
3.019AspAsp: 3.019 ± 1.433
4.227AspGlu: 4.227 ± 0.689
0.604AspPhe: 0.604 ± 0.372
3.623AspGly: 3.623 ± 0.586
1.208AspHis: 1.208 ± 0.903
3.623AspIle: 3.623 ± 0.237
2.415AspLys: 2.415 ± 1.805
3.623AspLeu: 3.623 ± 0.586
2.415AspMet: 2.415 ± 1.489
3.623AspAsn: 3.623 ± 0.586
2.415AspPro: 2.415 ± 0.982
1.812AspGln: 1.812 ± 0.293
0.604AspArg: 0.604 ± 0.451
4.831AspSer: 4.831 ± 2.155
3.019AspThr: 3.019 ± 1.038
3.623AspVal: 3.623 ± 0.237
0.0AspTrp: 0.0 ± 0.0
3.019AspTyr: 3.019 ± 0.61
0.0AspXaa: 0.0 ± 0.0
Glu
1.208GluAla: 1.208 ± 0.079
0.0GluCys: 0.0 ± 0.0
1.208GluAsp: 1.208 ± 0.079
1.208GluGlu: 1.208 ± 0.079
3.019GluPhe: 3.019 ± 0.61
3.019GluGly: 3.019 ± 0.214
0.604GluHis: 0.604 ± 0.451
6.039GluIle: 6.039 ± 2.043
3.019GluLys: 3.019 ± 0.61
3.019GluLeu: 3.019 ± 1.433
2.415GluMet: 2.415 ± 0.982
3.019GluAsn: 3.019 ± 0.61
1.812GluPro: 1.812 ± 0.293
2.415GluGln: 2.415 ± 0.158
3.019GluArg: 3.019 ± 1.433
3.019GluSer: 3.019 ± 0.214
3.623GluThr: 3.623 ± 1.41
5.435GluVal: 5.435 ± 0.768
1.208GluTrp: 1.208 ± 0.079
1.208GluTyr: 1.208 ± 0.903
0.0GluXaa: 0.0 ± 0.0
Phe
1.208PheAla: 1.208 ± 0.745
0.0PheCys: 0.0 ± 0.0
3.019PheAsp: 3.019 ± 0.61
1.208PheGlu: 1.208 ± 0.903
0.604PhePhe: 0.604 ± 0.372
5.435PheGly: 5.435 ± 0.056
1.208PheHis: 1.208 ± 0.079
3.019PheIle: 3.019 ± 1.433
2.415PheLys: 2.415 ± 0.158
2.415PheLeu: 2.415 ± 0.982
1.208PheMet: 1.208 ± 0.745
2.415PheAsn: 2.415 ± 0.665
2.415PhePro: 2.415 ± 0.158
1.812PheGln: 1.812 ± 0.293
1.208PheArg: 1.208 ± 0.079
3.623PheSer: 3.623 ± 1.41
1.812PheThr: 1.812 ± 0.293
2.415PheVal: 2.415 ± 0.982
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.415GlyAla: 2.415 ± 1.489
0.0GlyCys: 0.0 ± 0.0
1.208GlyAsp: 1.208 ± 0.079
3.623GlyGlu: 3.623 ± 0.237
3.623GlyPhe: 3.623 ± 0.237
4.227GlyGly: 4.227 ± 0.135
2.415GlyHis: 2.415 ± 0.158
7.85GlyIle: 7.85 ± 2.573
4.227GlyLys: 4.227 ± 2.336
3.623GlyLeu: 3.623 ± 0.586
1.812GlyMet: 1.812 ± 0.293
5.435GlyAsn: 5.435 ± 0.88
0.604GlyPro: 0.604 ± 0.372
1.208GlyGln: 1.208 ± 0.745
1.208GlyArg: 1.208 ± 0.079
2.415GlySer: 2.415 ± 0.665
3.623GlyThr: 3.623 ± 1.41
6.039GlyVal: 6.039 ± 0.428
2.415GlyTrp: 2.415 ± 0.158
2.415GlyTyr: 2.415 ± 0.982
0.0GlyXaa: 0.0 ± 0.0
His
0.604HisAla: 0.604 ± 0.372
0.0HisCys: 0.0 ± 0.0
0.604HisAsp: 0.604 ± 0.372
1.208HisGlu: 1.208 ± 0.903
0.604HisPhe: 0.604 ± 0.451
1.208HisGly: 1.208 ± 0.903
0.604HisHis: 0.604 ± 0.451
2.415HisIle: 2.415 ± 0.665
0.0HisLys: 0.0 ± 0.0
2.415HisLeu: 2.415 ± 0.158
0.604HisMet: 0.604 ± 0.372
1.208HisAsn: 1.208 ± 0.745
0.604HisPro: 0.604 ± 0.451
1.812HisGln: 1.812 ± 1.354
0.604HisArg: 0.604 ± 0.451
1.208HisSer: 1.208 ± 0.079
1.812HisThr: 1.812 ± 0.53
1.208HisVal: 1.208 ± 0.079
0.604HisTrp: 0.604 ± 0.451
0.604HisTyr: 0.604 ± 0.372
0.0HisXaa: 0.0 ± 0.0
Ile
4.831IleAla: 4.831 ± 0.316
0.604IleCys: 0.604 ± 0.451
4.831IleAsp: 4.831 ± 0.507
4.831IleGlu: 4.831 ± 1.14
2.415IlePhe: 2.415 ± 0.665
3.623IleGly: 3.623 ± 2.708
2.415IleHis: 2.415 ± 0.982
1.812IleIle: 1.812 ± 1.354
4.831IleLys: 4.831 ± 1.964
4.227IleLeu: 4.227 ± 2.336
0.0IleMet: 0.0 ± 0.0
7.85IleAsn: 7.85 ± 0.926
5.435IlePro: 5.435 ± 0.056
2.415IleGln: 2.415 ± 0.665
2.415IleArg: 2.415 ± 0.158
7.246IleSer: 7.246 ± 1.298
4.227IleThr: 4.227 ± 0.959
4.227IleVal: 4.227 ± 0.689
1.208IleTrp: 1.208 ± 0.079
3.019IleTyr: 3.019 ± 1.433
0.0IleXaa: 0.0 ± 0.0
Lys
1.812LysAla: 1.812 ± 0.293
0.0LysCys: 0.0 ± 0.0
3.623LysAsp: 3.623 ± 1.061
4.831LysGlu: 4.831 ± 1.14
3.623LysPhe: 3.623 ± 1.061
1.812LysGly: 1.812 ± 1.354
0.604LysHis: 0.604 ± 0.451
6.039LysIle: 6.039 ± 4.514
1.812LysLys: 1.812 ± 1.354
7.246LysLeu: 7.246 ± 2.122
0.604LysMet: 0.604 ± 0.451
2.415LysAsn: 2.415 ± 1.805
3.019LysPro: 3.019 ± 0.61
5.435LysGln: 5.435 ± 0.88
2.415LysArg: 2.415 ± 0.158
2.415LysSer: 2.415 ± 0.158
4.831LysThr: 4.831 ± 0.316
4.831LysVal: 4.831 ± 2.787
1.812LysTrp: 1.812 ± 0.53
0.604LysTyr: 0.604 ± 0.451
0.0LysXaa: 0.0 ± 0.0
Leu
6.643LeuAla: 6.643 ± 0.847
1.208LeuCys: 1.208 ± 0.745
3.019LeuAsp: 3.019 ± 1.433
3.019LeuGlu: 3.019 ± 0.61
5.435LeuPhe: 5.435 ± 0.768
4.227LeuGly: 4.227 ± 0.135
2.415LeuHis: 2.415 ± 0.982
3.019LeuIle: 3.019 ± 1.038
1.208LeuLys: 1.208 ± 0.903
7.85LeuLeu: 7.85 ± 0.926
1.812LeuMet: 1.812 ± 1.117
2.415LeuAsn: 2.415 ± 0.665
10.266LeuPro: 10.266 ± 2.211
5.435LeuGln: 5.435 ± 0.768
5.435LeuArg: 5.435 ± 0.768
6.039LeuSer: 6.039 ± 0.395
5.435LeuThr: 5.435 ± 1.703
4.227LeuVal: 4.227 ± 0.135
0.0LeuTrp: 0.0 ± 0.0
2.415LeuTyr: 2.415 ± 0.158
0.0LeuXaa: 0.0 ± 0.0
Met
2.415MetAla: 2.415 ± 1.489
0.0MetCys: 0.0 ± 0.0
3.019MetAsp: 3.019 ± 0.214
1.812MetGlu: 1.812 ± 0.53
2.415MetPhe: 2.415 ± 1.489
1.208MetGly: 1.208 ± 0.745
1.812MetHis: 1.812 ± 1.117
1.812MetIle: 1.812 ± 0.53
1.208MetLys: 1.208 ± 0.079
3.623MetLeu: 3.623 ± 0.237
1.208MetMet: 1.208 ± 0.745
1.208MetAsn: 1.208 ± 0.745
1.208MetPro: 1.208 ± 0.745
2.415MetGln: 2.415 ± 0.665
0.0MetArg: 0.0 ± 0.0
0.604MetSer: 0.604 ± 0.451
1.812MetThr: 1.812 ± 0.53
2.415MetVal: 2.415 ± 0.665
1.208MetTrp: 1.208 ± 0.903
1.812MetTyr: 1.812 ± 0.293
0.0MetXaa: 0.0 ± 0.0
Asn
9.058AsnAla: 9.058 ± 2.29
0.604AsnCys: 0.604 ± 0.372
1.812AsnAsp: 1.812 ± 0.53
3.623AsnGlu: 3.623 ± 1.885
0.604AsnPhe: 0.604 ± 0.451
4.831AsnGly: 4.831 ± 1.331
1.208AsnHis: 1.208 ± 0.745
7.85AsnIle: 7.85 ± 0.102
3.623AsnLys: 3.623 ± 1.885
4.831AsnLeu: 4.831 ± 0.507
3.019AsnMet: 3.019 ± 1.433
5.435AsnAsn: 5.435 ± 1.703
1.812AsnPro: 1.812 ± 0.53
2.415AsnGln: 2.415 ± 0.665
0.604AsnArg: 0.604 ± 0.372
1.812AsnSer: 1.812 ± 0.293
3.623AsnThr: 3.623 ± 1.41
7.246AsnVal: 7.246 ± 1.996
1.208AsnTrp: 1.208 ± 0.079
3.019AsnTyr: 3.019 ± 0.214
0.0AsnXaa: 0.0 ± 0.0
Pro
4.227ProAla: 4.227 ± 0.959
0.0ProCys: 0.0 ± 0.0
0.604ProAsp: 0.604 ± 0.451
1.812ProGlu: 1.812 ± 1.117
3.019ProPhe: 3.019 ± 1.038
2.415ProGly: 2.415 ± 0.665
0.0ProHis: 0.0 ± 0.0
4.831ProIle: 4.831 ± 0.507
3.623ProLys: 3.623 ± 1.061
3.623ProLeu: 3.623 ± 0.237
0.604ProMet: 0.604 ± 0.372
2.415ProAsn: 2.415 ± 0.982
1.208ProPro: 1.208 ± 0.745
1.812ProGln: 1.812 ± 0.53
3.019ProArg: 3.019 ± 0.214
3.019ProSer: 3.019 ± 0.214
5.435ProThr: 5.435 ± 1.703
3.019ProVal: 3.019 ± 1.038
1.812ProTrp: 1.812 ± 0.53
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.623GlnAla: 3.623 ± 0.586
0.604GlnCys: 0.604 ± 0.372
1.812GlnAsp: 1.812 ± 1.117
3.019GlnGlu: 3.019 ± 0.214
0.0GlnPhe: 0.0 ± 0.0
3.623GlnGly: 3.623 ± 0.237
0.604GlnHis: 0.604 ± 0.451
3.623GlnIle: 3.623 ± 0.237
4.831GlnLys: 4.831 ± 1.14
6.039GlnLeu: 6.039 ± 1.252
2.415GlnMet: 2.415 ± 0.665
2.415GlnAsn: 2.415 ± 0.665
3.623GlnPro: 3.623 ± 0.586
3.623GlnGln: 3.623 ± 1.061
5.435GlnArg: 5.435 ± 0.88
4.227GlnSer: 4.227 ± 0.135
3.623GlnThr: 3.623 ± 0.237
2.415GlnVal: 2.415 ± 0.982
0.0GlnTrp: 0.0 ± 0.0
0.604GlnTyr: 0.604 ± 0.451
0.0GlnXaa: 0.0 ± 0.0
Arg
3.019ArgAla: 3.019 ± 0.214
0.0ArgCys: 0.0 ± 0.0
2.415ArgAsp: 2.415 ± 0.665
1.208ArgGlu: 1.208 ± 0.079
1.208ArgPhe: 1.208 ± 0.903
3.019ArgGly: 3.019 ± 1.433
1.208ArgHis: 1.208 ± 0.903
1.812ArgIle: 1.812 ± 0.53
3.019ArgLys: 3.019 ± 0.214
3.623ArgLeu: 3.623 ± 0.237
0.604ArgMet: 0.604 ± 0.372
4.227ArgAsn: 4.227 ± 1.512
1.812ArgPro: 1.812 ± 1.117
4.831ArgGln: 4.831 ± 0.316
1.812ArgArg: 1.812 ± 0.53
1.208ArgSer: 1.208 ± 0.745
1.812ArgThr: 1.812 ± 0.293
3.623ArgVal: 3.623 ± 0.586
0.604ArgTrp: 0.604 ± 0.451
3.019ArgTyr: 3.019 ± 0.61
0.0ArgXaa: 0.0 ± 0.0
Ser
1.812SerAla: 1.812 ± 1.117
0.604SerCys: 0.604 ± 0.372
2.415SerAsp: 2.415 ± 1.489
3.019SerGlu: 3.019 ± 0.214
2.415SerPhe: 2.415 ± 0.158
3.019SerGly: 3.019 ± 0.61
0.0SerHis: 0.0 ± 0.0
2.415SerIle: 2.415 ± 0.665
4.831SerLys: 4.831 ± 1.14
4.227SerLeu: 4.227 ± 1.512
2.415SerMet: 2.415 ± 1.489
4.227SerAsn: 4.227 ± 0.959
1.208SerPro: 1.208 ± 0.903
6.643SerGln: 6.643 ± 0.023
3.623SerArg: 3.623 ± 0.237
5.435SerSer: 5.435 ± 0.056
4.831SerThr: 4.831 ± 2.155
1.812SerVal: 1.812 ± 0.293
1.812SerTrp: 1.812 ± 1.117
4.227SerTyr: 4.227 ± 0.689
0.0SerXaa: 0.0 ± 0.0
Thr
6.643ThrAla: 6.643 ± 4.095
1.208ThrCys: 1.208 ± 0.903
4.831ThrAsp: 4.831 ± 0.507
1.812ThrGlu: 1.812 ± 0.293
1.812ThrPhe: 1.812 ± 0.293
3.019ThrGly: 3.019 ± 1.038
1.208ThrHis: 1.208 ± 0.079
3.019ThrIle: 3.019 ± 0.214
8.454ThrLys: 8.454 ± 0.27
6.643ThrLeu: 6.643 ± 3.271
2.415ThrMet: 2.415 ± 0.158
4.227ThrAsn: 4.227 ± 0.959
0.604ThrPro: 0.604 ± 0.451
3.019ThrGln: 3.019 ± 0.214
0.604ThrArg: 0.604 ± 0.372
2.415ThrSer: 2.415 ± 0.158
4.227ThrThr: 4.227 ± 1.782
6.039ThrVal: 6.039 ± 2.075
1.208ThrTrp: 1.208 ± 0.079
1.812ThrTyr: 1.812 ± 0.293
0.0ThrXaa: 0.0 ± 0.0
Val
5.435ValAla: 5.435 ± 1.703
1.208ValCys: 1.208 ± 0.903
4.227ValAsp: 4.227 ± 0.135
3.623ValGlu: 3.623 ± 1.061
3.019ValPhe: 3.019 ± 0.214
3.019ValGly: 3.019 ± 0.61
1.208ValHis: 1.208 ± 0.079
2.415ValIle: 2.415 ± 0.665
3.623ValLys: 3.623 ± 2.708
4.831ValLeu: 4.831 ± 2.155
1.812ValMet: 1.812 ± 0.409
7.85ValAsn: 7.85 ± 1.545
4.831ValPro: 4.831 ± 0.507
2.415ValGln: 2.415 ± 0.158
5.435ValArg: 5.435 ± 1.591
3.623ValSer: 3.623 ± 1.41
2.415ValThr: 2.415 ± 0.158
3.019ValVal: 3.019 ± 1.038
0.604ValTrp: 0.604 ± 0.372
1.812ValTyr: 1.812 ± 0.293
0.0ValXaa: 0.0 ± 0.0
Trp
1.208TrpAla: 1.208 ± 0.745
0.0TrpCys: 0.0 ± 0.0
2.415TrpAsp: 2.415 ± 0.158
0.0TrpGlu: 0.0 ± 0.0
0.604TrpPhe: 0.604 ± 0.451
1.208TrpGly: 1.208 ± 0.745
0.0TrpHis: 0.0 ± 0.0
0.604TrpIle: 0.604 ± 0.451
0.0TrpLys: 0.0 ± 0.0
1.812TrpLeu: 1.812 ± 0.53
0.604TrpMet: 0.604 ± 0.372
1.812TrpAsn: 1.812 ± 1.354
1.208TrpPro: 1.208 ± 0.745
0.0TrpGln: 0.0 ± 0.0
0.604TrpArg: 0.604 ± 0.372
2.415TrpSer: 2.415 ± 0.982
1.812TrpThr: 1.812 ± 0.53
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.208TrpTyr: 1.208 ± 0.079
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.812TyrAla: 1.812 ± 1.354
0.0TyrCys: 0.0 ± 0.0
4.831TyrAsp: 4.831 ± 0.507
1.208TyrGlu: 1.208 ± 0.079
1.208TyrPhe: 1.208 ± 0.903
1.208TyrGly: 1.208 ± 0.079
0.0TyrHis: 0.0 ± 0.0
3.623TyrIle: 3.623 ± 1.061
2.415TyrLys: 2.415 ± 0.982
3.623TyrLeu: 3.623 ± 0.237
3.019TyrMet: 3.019 ± 1.228
0.604TyrAsn: 0.604 ± 0.451
0.0TyrPro: 0.0 ± 0.0
3.623TyrGln: 3.623 ± 0.586
1.208TyrArg: 1.208 ± 0.903
1.812TyrSer: 1.812 ± 1.117
3.019TyrThr: 3.019 ± 0.214
1.208TyrVal: 1.208 ± 0.745
0.0TyrTrp: 0.0 ± 0.0
1.812TyrTyr: 1.812 ± 0.53
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1657 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski