Amino acid dipepetide frequency for Acidianus filamentous virus 1 (isolate United States/Yellowstone) (AFV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.468AlaCys: 0.468 ± 0.23
2.967AlaAsp: 2.967 ± 0.566
4.216AlaGlu: 4.216 ± 0.705
2.655AlaPhe: 2.655 ± 0.564
2.03AlaGly: 2.03 ± 0.87
0.468AlaHis: 0.468 ± 0.293
5.153AlaIle: 5.153 ± 0.721
4.216AlaLys: 4.216 ± 0.893
4.528AlaLeu: 4.528 ± 1.238
1.405AlaMet: 1.405 ± 0.436
1.874AlaAsn: 1.874 ± 0.474
1.562AlaPro: 1.562 ± 0.427
1.093AlaGln: 1.093 ± 0.424
2.03AlaArg: 2.03 ± 0.532
3.435AlaSer: 3.435 ± 1.072
2.342AlaThr: 2.342 ± 0.794
4.685AlaVal: 4.685 ± 0.763
1.249AlaTrp: 1.249 ± 0.394
2.186AlaTyr: 2.186 ± 0.617
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.468CysCys: 0.468 ± 0.22
0.312CysAsp: 0.312 ± 0.192
0.312CysGlu: 0.312 ± 0.232
0.468CysPhe: 0.468 ± 0.33
1.249CysGly: 1.249 ± 0.414
0.468CysHis: 0.468 ± 0.337
1.093CysIle: 1.093 ± 0.416
1.874CysLys: 1.874 ± 0.563
1.093CysLeu: 1.093 ± 0.403
0.625CysMet: 0.625 ± 0.323
0.312CysAsn: 0.312 ± 0.21
0.937CysPro: 0.937 ± 0.393
0.625CysGln: 0.625 ± 0.301
0.468CysArg: 0.468 ± 0.278
0.937CysSer: 0.937 ± 0.28
0.625CysThr: 0.625 ± 0.281
0.468CysVal: 0.468 ± 0.288
0.0CysTrp: 0.0 ± 0.0
0.781CysTyr: 0.781 ± 0.291
0.0CysXaa: 0.0 ± 0.0
Asp
1.718AspAla: 1.718 ± 0.463
0.312AspCys: 0.312 ± 0.212
2.655AspAsp: 2.655 ± 0.577
5.309AspGlu: 5.309 ± 1.13
4.216AspPhe: 4.216 ± 0.835
2.498AspGly: 2.498 ± 0.572
0.156AspHis: 0.156 ± 0.169
5.778AspIle: 5.778 ± 0.834
5.309AspLys: 5.309 ± 0.871
4.528AspLeu: 4.528 ± 0.828
1.405AspMet: 1.405 ± 0.485
1.562AspAsn: 1.562 ± 0.458
1.249AspPro: 1.249 ± 0.564
0.625AspGln: 0.625 ± 0.306
2.811AspArg: 2.811 ± 0.649
3.435AspSer: 3.435 ± 0.891
2.186AspThr: 2.186 ± 0.517
3.435AspVal: 3.435 ± 0.643
0.781AspTrp: 0.781 ± 0.366
3.279AspTyr: 3.279 ± 0.649
0.0AspXaa: 0.0 ± 0.0
Glu
3.904GluAla: 3.904 ± 0.881
0.781GluCys: 0.781 ± 0.434
4.372GluAsp: 4.372 ± 0.664
7.339GluGlu: 7.339 ± 1.304
3.279GluPhe: 3.279 ± 0.917
2.186GluGly: 2.186 ± 0.504
0.781GluHis: 0.781 ± 0.328
7.339GluIle: 7.339 ± 1.187
5.934GluLys: 5.934 ± 1.522
7.651GluLeu: 7.651 ± 1.345
1.405GluMet: 1.405 ± 0.546
2.498GluAsn: 2.498 ± 0.848
1.405GluPro: 1.405 ± 0.424
2.498GluGln: 2.498 ± 0.586
2.811GluArg: 2.811 ± 0.636
4.216GluSer: 4.216 ± 0.719
4.216GluThr: 4.216 ± 0.974
5.778GluVal: 5.778 ± 0.969
0.468GluTrp: 0.468 ± 0.247
3.592GluTyr: 3.592 ± 0.899
0.0GluXaa: 0.0 ± 0.0
Phe
2.655PheAla: 2.655 ± 0.47
0.781PheCys: 0.781 ± 0.348
2.03PheAsp: 2.03 ± 0.476
3.123PheGlu: 3.123 ± 0.699
1.562PhePhe: 1.562 ± 0.418
2.655PheGly: 2.655 ± 0.585
1.405PheHis: 1.405 ± 0.464
3.904PheIle: 3.904 ± 0.491
2.811PheLys: 2.811 ± 0.696
4.997PheLeu: 4.997 ± 1.282
1.249PheMet: 1.249 ± 0.367
1.405PheAsn: 1.405 ± 0.442
2.03PhePro: 2.03 ± 0.496
0.937PheGln: 0.937 ± 0.323
2.498PheArg: 2.498 ± 0.612
3.123PheSer: 3.123 ± 0.543
2.186PheThr: 2.186 ± 0.616
2.655PheVal: 2.655 ± 0.542
0.156PheTrp: 0.156 ± 0.18
1.874PheTyr: 1.874 ± 0.536
0.0PheXaa: 0.0 ± 0.0
Gly
2.342GlyAla: 2.342 ± 0.809
1.405GlyCys: 1.405 ± 0.59
2.967GlyAsp: 2.967 ± 0.483
2.186GlyGlu: 2.186 ± 0.651
2.655GlyPhe: 2.655 ± 0.769
2.655GlyGly: 2.655 ± 0.721
1.093GlyHis: 1.093 ± 0.502
4.528GlyIle: 4.528 ± 0.721
4.997GlyLys: 4.997 ± 0.753
5.465GlyLeu: 5.465 ± 0.788
1.874GlyMet: 1.874 ± 0.509
2.655GlyAsn: 2.655 ± 0.705
0.0GlyPro: 0.0 ± 0.0
2.342GlyGln: 2.342 ± 0.953
2.186GlyArg: 2.186 ± 0.74
3.592GlySer: 3.592 ± 0.667
3.123GlyThr: 3.123 ± 0.976
4.372GlyVal: 4.372 ± 0.906
0.312GlyTrp: 0.312 ± 0.185
3.279GlyTyr: 3.279 ± 0.73
0.0GlyXaa: 0.0 ± 0.0
His
0.937HisAla: 0.937 ± 0.413
0.156HisCys: 0.156 ± 0.142
0.468HisAsp: 0.468 ± 0.248
1.562HisGlu: 1.562 ± 0.503
0.312HisPhe: 0.312 ± 0.21
0.781HisGly: 0.781 ± 0.324
0.0HisHis: 0.0 ± 0.0
1.249HisIle: 1.249 ± 0.358
0.937HisLys: 0.937 ± 0.341
0.937HisLeu: 0.937 ± 0.311
0.312HisMet: 0.312 ± 0.179
0.625HisAsn: 0.625 ± 0.3
0.312HisPro: 0.312 ± 0.219
0.156HisGln: 0.156 ± 0.167
0.625HisArg: 0.625 ± 0.321
0.781HisSer: 0.781 ± 0.396
0.781HisThr: 0.781 ± 0.411
0.781HisVal: 0.781 ± 0.404
0.0HisTrp: 0.0 ± 0.0
0.156HisTyr: 0.156 ± 0.115
0.0HisXaa: 0.0 ± 0.0
Ile
5.934IleAla: 5.934 ± 0.891
0.625IleCys: 0.625 ± 0.276
5.465IleAsp: 5.465 ± 1.16
6.402IleGlu: 6.402 ± 1.436
3.592IlePhe: 3.592 ± 0.672
3.748IleGly: 3.748 ± 0.571
0.781IleHis: 0.781 ± 0.313
6.09IleIle: 6.09 ± 1.225
4.997IleLys: 4.997 ± 1.199
6.715IleLeu: 6.715 ± 0.998
2.498IleMet: 2.498 ± 0.623
4.06IleAsn: 4.06 ± 0.676
4.841IlePro: 4.841 ± 0.894
4.06IleGln: 4.06 ± 0.832
4.06IleArg: 4.06 ± 0.828
5.934IleSer: 5.934 ± 0.929
4.841IleThr: 4.841 ± 0.829
5.621IleVal: 5.621 ± 0.843
0.781IleTrp: 0.781 ± 0.338
4.997IleTyr: 4.997 ± 0.815
0.0IleXaa: 0.0 ± 0.0
Lys
3.592LysAla: 3.592 ± 0.595
0.468LysCys: 0.468 ± 0.265
2.655LysAsp: 2.655 ± 0.627
5.621LysGlu: 5.621 ± 1.137
2.186LysPhe: 2.186 ± 0.524
3.279LysGly: 3.279 ± 0.594
0.625LysHis: 0.625 ± 0.294
5.153LysIle: 5.153 ± 1.238
6.09LysLys: 6.09 ± 1.434
9.681LysLeu: 9.681 ± 1.114
1.405LysMet: 1.405 ± 0.454
4.372LysAsn: 4.372 ± 0.8
2.342LysPro: 2.342 ± 0.66
3.279LysGln: 3.279 ± 0.666
2.655LysArg: 2.655 ± 0.69
4.372LysSer: 4.372 ± 0.896
5.465LysThr: 5.465 ± 0.962
5.934LysVal: 5.934 ± 0.925
0.468LysTrp: 0.468 ± 0.3
4.685LysTyr: 4.685 ± 0.775
0.0LysXaa: 0.0 ± 0.0
Leu
4.997LeuAla: 4.997 ± 0.628
0.781LeuCys: 0.781 ± 0.31
5.778LeuAsp: 5.778 ± 0.879
7.027LeuGlu: 7.027 ± 1.068
3.279LeuPhe: 3.279 ± 0.741
5.934LeuGly: 5.934 ± 1.113
0.937LeuHis: 0.937 ± 0.245
8.12LeuIle: 8.12 ± 1.087
7.964LeuLys: 7.964 ± 0.994
8.588LeuLeu: 8.588 ± 1.324
2.03LeuMet: 2.03 ± 0.508
5.778LeuAsn: 5.778 ± 0.916
4.06LeuPro: 4.06 ± 0.892
2.811LeuGln: 2.811 ± 0.746
3.592LeuArg: 3.592 ± 0.945
6.246LeuSer: 6.246 ± 1.131
5.153LeuThr: 5.153 ± 0.768
6.246LeuVal: 6.246 ± 0.945
0.625LeuTrp: 0.625 ± 0.294
4.528LeuTyr: 4.528 ± 0.737
0.0LeuXaa: 0.0 ± 0.0
Met
1.405MetAla: 1.405 ± 0.502
0.156MetCys: 0.156 ± 0.142
0.625MetAsp: 0.625 ± 0.284
1.249MetGlu: 1.249 ± 0.482
0.625MetPhe: 0.625 ± 0.262
1.718MetGly: 1.718 ± 0.539
0.156MetHis: 0.156 ± 0.142
1.718MetIle: 1.718 ± 0.597
1.093MetLys: 1.093 ± 0.364
3.123MetLeu: 3.123 ± 0.852
0.781MetMet: 0.781 ± 0.425
0.781MetAsn: 0.781 ± 0.276
1.093MetPro: 1.093 ± 0.39
1.562MetGln: 1.562 ± 0.446
2.03MetArg: 2.03 ± 0.646
3.123MetSer: 3.123 ± 0.654
2.03MetThr: 2.03 ± 0.453
1.562MetVal: 1.562 ± 0.449
0.0MetTrp: 0.0 ± 0.0
1.405MetTyr: 1.405 ± 0.368
0.0MetXaa: 0.0 ± 0.0
Asn
2.186AsnAla: 2.186 ± 0.51
1.562AsnCys: 1.562 ± 0.448
2.967AsnAsp: 2.967 ± 0.788
3.435AsnGlu: 3.435 ± 0.69
1.249AsnPhe: 1.249 ± 0.342
3.748AsnGly: 3.748 ± 0.729
0.468AsnHis: 0.468 ± 0.25
3.279AsnIle: 3.279 ± 0.617
3.748AsnLys: 3.748 ± 0.584
3.435AsnLeu: 3.435 ± 0.658
1.249AsnMet: 1.249 ± 0.388
1.562AsnAsn: 1.562 ± 0.435
1.718AsnPro: 1.718 ± 0.47
1.874AsnGln: 1.874 ± 0.685
2.811AsnArg: 2.811 ± 0.741
2.655AsnSer: 2.655 ± 0.587
2.498AsnThr: 2.498 ± 0.593
4.06AsnVal: 4.06 ± 0.923
0.625AsnTrp: 0.625 ± 0.328
3.123AsnTyr: 3.123 ± 0.557
0.0AsnXaa: 0.0 ± 0.0
Pro
0.937ProAla: 0.937 ± 0.336
0.468ProCys: 0.468 ± 0.286
2.342ProAsp: 2.342 ± 0.632
2.811ProGlu: 2.811 ± 0.597
2.655ProPhe: 2.655 ± 0.434
1.405ProGly: 1.405 ± 0.456
0.312ProHis: 0.312 ± 0.206
2.811ProIle: 2.811 ± 0.717
2.186ProLys: 2.186 ± 0.707
3.748ProLeu: 3.748 ± 0.839
0.625ProMet: 0.625 ± 0.341
2.186ProAsn: 2.186 ± 0.631
1.093ProPro: 1.093 ± 0.349
0.937ProGln: 0.937 ± 0.446
0.781ProArg: 0.781 ± 0.238
2.811ProSer: 2.811 ± 0.691
1.718ProThr: 1.718 ± 0.599
3.123ProVal: 3.123 ± 0.862
0.156ProTrp: 0.156 ± 0.155
1.874ProTyr: 1.874 ± 0.457
0.0ProXaa: 0.0 ± 0.0
Gln
0.625GlnAla: 0.625 ± 0.304
0.781GlnCys: 0.781 ± 0.416
1.718GlnAsp: 1.718 ± 0.531
1.718GlnGlu: 1.718 ± 0.473
1.718GlnPhe: 1.718 ± 0.589
1.718GlnGly: 1.718 ± 0.552
0.156GlnHis: 0.156 ± 0.151
3.279GlnIle: 3.279 ± 0.825
2.342GlnLys: 2.342 ± 0.528
2.186GlnLeu: 2.186 ± 0.499
0.625GlnMet: 0.625 ± 0.233
2.186GlnAsn: 2.186 ± 0.62
1.874GlnPro: 1.874 ± 1.007
1.093GlnGln: 1.093 ± 0.666
1.718GlnArg: 1.718 ± 0.497
2.342GlnSer: 2.342 ± 0.885
2.811GlnThr: 2.811 ± 0.759
1.718GlnVal: 1.718 ± 0.417
0.468GlnTrp: 0.468 ± 0.231
3.435GlnTyr: 3.435 ± 0.722
0.0GlnXaa: 0.0 ± 0.0
Arg
2.186ArgAla: 2.186 ± 0.555
0.781ArgCys: 0.781 ± 0.437
1.562ArgAsp: 1.562 ± 0.578
2.811ArgGlu: 2.811 ± 0.68
1.562ArgPhe: 1.562 ± 0.488
2.498ArgGly: 2.498 ± 0.423
0.625ArgHis: 0.625 ± 0.283
3.904ArgIle: 3.904 ± 0.881
4.06ArgLys: 4.06 ± 1.15
6.09ArgLeu: 6.09 ± 1.371
0.781ArgMet: 0.781 ± 0.332
1.874ArgAsn: 1.874 ± 0.594
1.249ArgPro: 1.249 ± 0.42
2.186ArgGln: 2.186 ± 0.617
2.186ArgArg: 2.186 ± 0.747
2.342ArgSer: 2.342 ± 0.758
1.874ArgThr: 1.874 ± 0.571
2.811ArgVal: 2.811 ± 0.696
0.312ArgTrp: 0.312 ± 0.206
2.186ArgTyr: 2.186 ± 0.625
0.0ArgXaa: 0.0 ± 0.0
Ser
2.967SerAla: 2.967 ± 1.054
0.781SerCys: 0.781 ± 0.367
3.592SerAsp: 3.592 ± 0.616
4.216SerGlu: 4.216 ± 0.633
3.904SerPhe: 3.904 ± 0.642
4.372SerGly: 4.372 ± 0.963
0.781SerHis: 0.781 ± 0.287
5.934SerIle: 5.934 ± 0.748
4.372SerLys: 4.372 ± 0.746
5.621SerLeu: 5.621 ± 1.136
2.498SerMet: 2.498 ± 0.608
3.279SerAsn: 3.279 ± 0.668
2.342SerPro: 2.342 ± 0.608
2.186SerGln: 2.186 ± 0.839
1.874SerArg: 1.874 ± 0.544
4.528SerSer: 4.528 ± 0.889
3.435SerThr: 3.435 ± 0.902
5.153SerVal: 5.153 ± 0.854
0.625SerTrp: 0.625 ± 0.288
3.904SerTyr: 3.904 ± 0.586
0.0SerXaa: 0.0 ± 0.0
Thr
3.279ThrAla: 3.279 ± 0.873
0.781ThrCys: 0.781 ± 0.353
4.372ThrAsp: 4.372 ± 1.068
5.309ThrGlu: 5.309 ± 1.097
3.123ThrPhe: 3.123 ± 0.642
3.904ThrGly: 3.904 ± 0.746
0.625ThrHis: 0.625 ± 0.27
4.216ThrIle: 4.216 ± 0.909
2.655ThrLys: 2.655 ± 0.573
4.372ThrLeu: 4.372 ± 0.879
0.937ThrMet: 0.937 ± 0.539
2.342ThrAsn: 2.342 ± 0.489
1.718ThrPro: 1.718 ± 0.506
2.655ThrGln: 2.655 ± 0.776
1.562ThrArg: 1.562 ± 0.537
3.435ThrSer: 3.435 ± 0.626
2.03ThrThr: 2.03 ± 0.686
5.465ThrVal: 5.465 ± 1.287
0.625ThrTrp: 0.625 ± 0.295
2.655ThrTyr: 2.655 ± 0.73
0.0ThrXaa: 0.0 ± 0.0
Val
4.372ValAla: 4.372 ± 1.154
0.937ValCys: 0.937 ± 0.4
4.685ValAsp: 4.685 ± 0.893
4.997ValGlu: 4.997 ± 1.008
1.874ValPhe: 1.874 ± 0.431
3.904ValGly: 3.904 ± 0.826
1.093ValHis: 1.093 ± 0.377
5.934ValIle: 5.934 ± 0.891
5.309ValLys: 5.309 ± 1.067
6.09ValLeu: 6.09 ± 0.91
2.498ValMet: 2.498 ± 0.9
4.841ValAsn: 4.841 ± 0.819
4.06ValPro: 4.06 ± 0.84
1.249ValGln: 1.249 ± 0.385
3.592ValArg: 3.592 ± 0.624
4.528ValSer: 4.528 ± 0.717
4.528ValThr: 4.528 ± 1.02
2.967ValVal: 2.967 ± 0.796
0.625ValTrp: 0.625 ± 0.289
4.216ValTyr: 4.216 ± 0.822
0.0ValXaa: 0.0 ± 0.0
Trp
0.468TrpAla: 0.468 ± 0.196
0.0TrpCys: 0.0 ± 0.0
0.156TrpAsp: 0.156 ± 0.171
0.156TrpGlu: 0.156 ± 0.152
0.625TrpPhe: 0.625 ± 0.278
0.468TrpGly: 0.468 ± 0.291
0.156TrpHis: 0.156 ± 0.115
0.625TrpIle: 0.625 ± 0.3
1.093TrpLys: 1.093 ± 0.489
0.312TrpLeu: 0.312 ± 0.202
0.312TrpMet: 0.312 ± 0.204
0.781TrpAsn: 0.781 ± 0.315
0.0TrpPro: 0.0 ± 0.0
0.312TrpGln: 0.312 ± 0.193
0.781TrpArg: 0.781 ± 0.307
0.312TrpSer: 0.312 ± 0.208
0.312TrpThr: 0.312 ± 0.199
1.249TrpVal: 1.249 ± 0.417
0.0TrpTrp: 0.0 ± 0.0
0.937TrpTyr: 0.937 ± 0.486
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.06TyrAla: 4.06 ± 0.579
0.625TyrCys: 0.625 ± 0.405
1.562TyrAsp: 1.562 ± 0.416
2.655TyrGlu: 2.655 ± 0.393
2.498TyrPhe: 2.498 ± 0.696
3.279TyrGly: 3.279 ± 0.808
0.781TyrHis: 0.781 ± 0.31
5.934TyrIle: 5.934 ± 0.845
2.498TyrLys: 2.498 ± 0.688
5.309TyrLeu: 5.309 ± 0.87
1.562TyrMet: 1.562 ± 0.61
3.279TyrAsn: 3.279 ± 0.622
1.093TyrPro: 1.093 ± 0.396
2.03TyrGln: 2.03 ± 0.642
2.811TyrArg: 2.811 ± 0.837
4.216TyrSer: 4.216 ± 0.93
3.904TyrThr: 3.904 ± 0.522
4.216TyrVal: 4.216 ± 1.055
0.781TyrTrp: 0.781 ± 0.322
3.123TyrTyr: 3.123 ± 0.656
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 40 proteins (6405 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski