Amino acid dipepetide frequency for Auricularia subglabra (strain TFB-10046 / SS5) (White-rot fungus) (Auricularia delicata (strain TFB10046))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.435AlaAla: 13.435 ± 0.127
1.716AlaCys: 1.716 ± 0.028
5.388AlaAsp: 5.388 ± 0.066
5.463AlaGlu: 5.463 ± 0.061
3.866AlaPhe: 3.866 ± 0.056
6.774AlaGly: 6.774 ± 0.067
2.985AlaHis: 2.985 ± 0.045
3.868AlaIle: 3.868 ± 0.054
3.52AlaLys: 3.52 ± 0.049
11.05AlaLeu: 11.05 ± 0.103
2.167AlaMet: 2.167 ± 0.037
2.602AlaAsn: 2.602 ± 0.038
8.055AlaPro: 8.055 ± 0.094
4.168AlaGln: 4.168 ± 0.056
8.132AlaArg: 8.132 ± 0.084
8.171AlaSer: 8.171 ± 0.086
5.84AlaThr: 5.84 ± 0.059
6.919AlaVal: 6.919 ± 0.07
1.52AlaTrp: 1.52 ± 0.025
2.238AlaTyr: 2.238 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
1.761CysAla: 1.761 ± 0.031
0.395CysCys: 0.395 ± 0.018
0.927CysAsp: 0.927 ± 0.024
0.713CysGlu: 0.713 ± 0.02
0.632CysPhe: 0.632 ± 0.018
1.328CysGly: 1.328 ± 0.044
0.435CysHis: 0.435 ± 0.018
0.659CysIle: 0.659 ± 0.02
0.578CysLys: 0.578 ± 0.02
1.465CysLeu: 1.465 ± 0.032
0.355CysMet: 0.355 ± 0.015
0.466CysAsn: 0.466 ± 0.016
1.246CysPro: 1.246 ± 0.028
0.485CysGln: 0.485 ± 0.016
1.107CysArg: 1.107 ± 0.025
1.32CysSer: 1.32 ± 0.028
1.005CysThr: 1.005 ± 0.025
1.064CysVal: 1.064 ± 0.024
0.285CysTrp: 0.285 ± 0.013
0.352CysTyr: 0.352 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
6.837AspAla: 6.837 ± 0.065
0.893AspCys: 0.893 ± 0.025
5.111AspAsp: 5.111 ± 0.086
4.306AspGlu: 4.306 ± 0.062
2.155AspPhe: 2.155 ± 0.042
4.525AspGly: 4.525 ± 0.057
1.269AspHis: 1.269 ± 0.026
2.649AspIle: 2.649 ± 0.038
1.856AspLys: 1.856 ± 0.039
5.135AspLeu: 5.135 ± 0.055
1.211AspMet: 1.211 ± 0.024
1.496AspAsn: 1.496 ± 0.028
3.508AspPro: 3.508 ± 0.042
1.416AspGln: 1.416 ± 0.028
3.139AspArg: 3.139 ± 0.046
3.795AspSer: 3.795 ± 0.055
2.805AspThr: 2.805 ± 0.044
4.358AspVal: 4.358 ± 0.053
1.036AspTrp: 1.036 ± 0.023
1.394AspTyr: 1.394 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
5.054GluAla: 5.054 ± 0.063
0.785GluCys: 0.785 ± 0.019
3.743GluAsp: 3.743 ± 0.053
3.838GluGlu: 3.838 ± 0.068
1.846GluPhe: 1.846 ± 0.036
3.066GluGly: 3.066 ± 0.043
1.747GluHis: 1.747 ± 0.031
2.226GluIle: 2.226 ± 0.038
2.107GluLys: 2.107 ± 0.042
5.786GluLeu: 5.786 ± 0.067
1.158GluMet: 1.158 ± 0.026
1.489GluAsn: 1.489 ± 0.026
3.122GluPro: 3.122 ± 0.055
2.089GluGln: 2.089 ± 0.037
4.23GluArg: 4.23 ± 0.058
3.342GluSer: 3.342 ± 0.044
2.798GluThr: 2.798 ± 0.039
3.201GluVal: 3.201 ± 0.046
0.903GluTrp: 0.903 ± 0.026
1.377GluTyr: 1.377 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
3.772PheAla: 3.772 ± 0.049
0.617PheCys: 0.617 ± 0.019
2.263PheAsp: 2.263 ± 0.038
1.874PheGlu: 1.874 ± 0.036
1.358PhePhe: 1.358 ± 0.032
2.403PheGly: 2.403 ± 0.039
0.951PheHis: 0.951 ± 0.026
1.494PheIle: 1.494 ± 0.03
1.192PheLys: 1.192 ± 0.026
3.257PheLeu: 3.257 ± 0.053
0.736PheMet: 0.736 ± 0.023
1.188PheAsn: 1.188 ± 0.027
2.225PhePro: 2.225 ± 0.032
1.046PheGln: 1.046 ± 0.02
2.186PheArg: 2.186 ± 0.036
2.716PheSer: 2.716 ± 0.042
1.925PheThr: 1.925 ± 0.038
2.649PheVal: 2.649 ± 0.037
0.633PheTrp: 0.633 ± 0.019
0.896PheTyr: 0.896 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
6.25GlyAla: 6.25 ± 0.078
1.064GlyCys: 1.064 ± 0.027
3.755GlyAsp: 3.755 ± 0.058
3.295GlyGlu: 3.295 ± 0.046
2.261GlyPhe: 2.261 ± 0.039
5.117GlyGly: 5.117 ± 0.09
1.858GlyHis: 1.858 ± 0.037
2.691GlyIle: 2.691 ± 0.039
2.586GlyLys: 2.586 ± 0.043
5.668GlyLeu: 5.668 ± 0.056
1.356GlyMet: 1.356 ± 0.031
1.964GlyAsn: 1.964 ± 0.036
3.883GlyPro: 3.883 ± 0.047
2.191GlyGln: 2.191 ± 0.034
4.619GlyArg: 4.619 ± 0.057
4.971GlySer: 4.971 ± 0.064
3.784GlyThr: 3.784 ± 0.047
4.216GlyVal: 4.216 ± 0.051
1.06GlyTrp: 1.06 ± 0.026
1.589GlyTyr: 1.589 ± 0.036
0.0GlyXaa: 0.0 ± 0.0
His
2.96HisAla: 2.96 ± 0.045
0.54HisCys: 0.54 ± 0.02
1.538HisAsp: 1.538 ± 0.03
1.458HisGlu: 1.458 ± 0.028
1.007HisPhe: 1.007 ± 0.023
1.945HisGly: 1.945 ± 0.036
0.814HisHis: 0.814 ± 0.025
1.341HisIle: 1.341 ± 0.028
0.866HisLys: 0.866 ± 0.02
2.856HisLeu: 2.856 ± 0.047
0.547HisMet: 0.547 ± 0.017
0.744HisAsn: 0.744 ± 0.02
2.002HisPro: 2.002 ± 0.034
0.807HisGln: 0.807 ± 0.021
2.003HisArg: 2.003 ± 0.033
1.911HisSer: 1.911 ± 0.037
1.549HisThr: 1.549 ± 0.026
1.994HisVal: 1.994 ± 0.032
0.463HisTrp: 0.463 ± 0.015
0.636HisTyr: 0.636 ± 0.021
0.0HisXaa: 0.0 ± 0.0
Ile
4.2IleAla: 4.2 ± 0.05
0.757IleCys: 0.757 ± 0.023
2.5IleAsp: 2.5 ± 0.041
2.062IleGlu: 2.062 ± 0.035
1.455IlePhe: 1.455 ± 0.032
2.306IleGly: 2.306 ± 0.036
1.059IleHis: 1.059 ± 0.026
1.696IleIle: 1.696 ± 0.034
1.193IleLys: 1.193 ± 0.026
3.725IleLeu: 3.725 ± 0.05
0.723IleMet: 0.723 ± 0.022
1.103IleAsn: 1.103 ± 0.027
2.773IlePro: 2.773 ± 0.039
1.341IleGln: 1.341 ± 0.028
2.748IleArg: 2.748 ± 0.039
2.897IleSer: 2.897 ± 0.04
2.136IleThr: 2.136 ± 0.035
2.915IleVal: 2.915 ± 0.045
0.721IleTrp: 0.721 ± 0.021
0.997IleTyr: 0.997 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
3.637LysAla: 3.637 ± 0.055
0.531LysCys: 0.531 ± 0.018
1.956LysAsp: 1.956 ± 0.038
1.956LysGlu: 1.956 ± 0.037
1.075LysPhe: 1.075 ± 0.026
2.204LysGly: 2.204 ± 0.044
1.029LysHis: 1.029 ± 0.023
1.38LysIle: 1.38 ± 0.028
2.168LysLys: 2.168 ± 0.055
3.236LysLeu: 3.236 ± 0.046
0.698LysMet: 0.698 ± 0.022
1.044LysAsn: 1.044 ± 0.027
2.042LysPro: 2.042 ± 0.037
1.162LysGln: 1.162 ± 0.027
3.121LysArg: 3.121 ± 0.051
2.221LysSer: 2.221 ± 0.038
2.11LysThr: 2.11 ± 0.038
1.941LysVal: 1.941 ± 0.036
0.524LysTrp: 0.524 ± 0.017
0.97LysTyr: 0.97 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
10.294LeuAla: 10.294 ± 0.095
1.709LeuCys: 1.709 ± 0.033
5.812LeuAsp: 5.812 ± 0.066
5.394LeuGlu: 5.394 ± 0.067
3.298LeuPhe: 3.298 ± 0.05
5.584LeuGly: 5.584 ± 0.063
2.882LeuHis: 2.882 ± 0.043
3.146LeuIle: 3.146 ± 0.047
3.171LeuLys: 3.171 ± 0.039
9.047LeuLeu: 9.047 ± 0.103
1.569LeuMet: 1.569 ± 0.031
2.681LeuAsn: 2.681 ± 0.04
6.995LeuPro: 6.995 ± 0.074
3.586LeuGln: 3.586 ± 0.048
8.221LeuArg: 8.221 ± 0.082
7.462LeuSer: 7.462 ± 0.069
4.977LeuThr: 4.977 ± 0.053
6.252LeuVal: 6.252 ± 0.078
1.51LeuTrp: 1.51 ± 0.035
2.203LeuTyr: 2.203 ± 0.036
0.0LeuXaa: 0.0 ± 0.0
Met
1.925MetAla: 1.925 ± 0.036
0.305MetCys: 0.305 ± 0.012
1.153MetAsp: 1.153 ± 0.024
0.956MetGlu: 0.956 ± 0.027
0.697MetPhe: 0.697 ± 0.018
1.031MetGly: 1.031 ± 0.025
0.619MetHis: 0.619 ± 0.019
0.625MetIle: 0.625 ± 0.02
0.637MetLys: 0.637 ± 0.019
2.05MetLeu: 2.05 ± 0.033
0.402MetMet: 0.402 ± 0.013
0.553MetAsn: 0.553 ± 0.017
1.563MetPro: 1.563 ± 0.029
0.758MetGln: 0.758 ± 0.019
1.524MetArg: 1.524 ± 0.028
1.705MetSer: 1.705 ± 0.034
1.171MetThr: 1.171 ± 0.024
1.063MetVal: 1.063 ± 0.029
0.262MetTrp: 0.262 ± 0.014
0.465MetTyr: 0.465 ± 0.018
0.0MetXaa: 0.0 ± 0.0
Asn
3.158AsnAla: 3.158 ± 0.039
0.469AsnCys: 0.469 ± 0.018
1.624AsnAsp: 1.624 ± 0.03
1.448AsnGlu: 1.448 ± 0.03
1.026AsnPhe: 1.026 ± 0.024
2.246AsnGly: 2.246 ± 0.043
0.623AsnHis: 0.623 ± 0.017
1.373AsnIle: 1.373 ± 0.03
0.918AsnLys: 0.918 ± 0.024
2.545AsnLeu: 2.545 ± 0.038
0.621AsnMet: 0.621 ± 0.019
0.904AsnAsn: 0.904 ± 0.026
1.798AsnPro: 1.798 ± 0.036
0.759AsnGln: 0.759 ± 0.024
1.551AsnArg: 1.551 ± 0.034
1.78AsnSer: 1.78 ± 0.033
1.588AsnThr: 1.588 ± 0.032
2.126AsnVal: 2.126 ± 0.036
0.443AsnTrp: 0.443 ± 0.018
0.702AsnTyr: 0.702 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
8.676ProAla: 8.676 ± 0.109
0.889ProCys: 0.889 ± 0.025
3.877ProAsp: 3.877 ± 0.049
3.851ProGlu: 3.851 ± 0.055
2.204ProPhe: 2.204 ± 0.034
4.648ProGly: 4.648 ± 0.05
1.792ProHis: 1.792 ± 0.033
2.201ProIle: 2.201 ± 0.037
2.128ProLys: 2.128 ± 0.032
5.73ProLeu: 5.73 ± 0.07
1.093ProMet: 1.093 ± 0.028
1.842ProAsn: 1.842 ± 0.032
7.392ProPro: 7.392 ± 0.14
2.431ProGln: 2.431 ± 0.044
5.109ProArg: 5.109 ± 0.057
6.353ProSer: 6.353 ± 0.088
4.185ProThr: 4.185 ± 0.058
4.617ProVal: 4.617 ± 0.057
0.824ProTrp: 0.824 ± 0.026
1.417ProTyr: 1.417 ± 0.026
0.001ProXaa: 0.001 ± 0.001
Gln
3.468GlnAla: 3.468 ± 0.05
0.546GlnCys: 0.546 ± 0.019
1.767GlnAsp: 1.767 ± 0.035
1.752GlnGlu: 1.752 ± 0.034
1.181GlnPhe: 1.181 ± 0.024
1.893GlnGly: 1.893 ± 0.037
1.19GlnHis: 1.19 ± 0.028
1.246GlnIle: 1.246 ± 0.027
1.178GlnLys: 1.178 ± 0.024
3.744GlnLeu: 3.744 ± 0.043
0.696GlnMet: 0.696 ± 0.018
0.938GlnAsn: 0.938 ± 0.02
2.571GlnPro: 2.571 ± 0.048
1.934GlnGln: 1.934 ± 0.079
2.985GlnArg: 2.985 ± 0.049
2.39GlnSer: 2.39 ± 0.035
1.918GlnThr: 1.918 ± 0.036
1.961GlnVal: 1.961 ± 0.033
0.593GlnTrp: 0.593 ± 0.02
0.947GlnTyr: 0.947 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
8.141ArgAla: 8.141 ± 0.078
1.349ArgCys: 1.349 ± 0.03
3.889ArgAsp: 3.889 ± 0.047
4.087ArgGlu: 4.087 ± 0.056
2.471ArgPhe: 2.471 ± 0.041
4.339ArgGly: 4.339 ± 0.051
1.967ArgHis: 1.967 ± 0.036
3.139ArgIle: 3.139 ± 0.047
2.971ArgLys: 2.971 ± 0.044
7.179ArgLeu: 7.179 ± 0.071
1.556ArgMet: 1.556 ± 0.03
2.015ArgAsn: 2.015 ± 0.032
4.634ArgPro: 4.634 ± 0.059
2.506ArgGln: 2.506 ± 0.044
6.968ArgArg: 6.968 ± 0.088
5.333ArgSer: 5.333 ± 0.06
4.15ArgThr: 4.15 ± 0.051
4.865ArgVal: 4.865 ± 0.055
1.24ArgTrp: 1.24 ± 0.027
1.685ArgTyr: 1.685 ± 0.034
0.0ArgXaa: 0.0 ± 0.0
Ser
7.859SerAla: 7.859 ± 0.069
1.108SerCys: 1.108 ± 0.023
4.17SerAsp: 4.17 ± 0.055
3.325SerGlu: 3.325 ± 0.049
2.666SerPhe: 2.666 ± 0.044
5.067SerGly: 5.067 ± 0.059
2.045SerHis: 2.045 ± 0.037
2.988SerIle: 2.988 ± 0.043
2.359SerLys: 2.359 ± 0.044
7.195SerLeu: 7.195 ± 0.075
1.442SerMet: 1.442 ± 0.029
2.039SerAsn: 2.039 ± 0.033
5.73SerPro: 5.73 ± 0.079
2.632SerGln: 2.632 ± 0.037
5.345SerArg: 5.345 ± 0.068
7.425SerSer: 7.425 ± 0.1
4.844SerThr: 4.844 ± 0.072
4.702SerVal: 4.702 ± 0.054
1.116SerTrp: 1.116 ± 0.025
1.687SerTyr: 1.687 ± 0.031
0.0SerXaa: 0.0 ± 0.0
Thr
5.842ThrAla: 5.842 ± 0.067
1.003ThrCys: 1.003 ± 0.027
2.687ThrAsp: 2.687 ± 0.046
2.396ThrGlu: 2.396 ± 0.039
2.182ThrPhe: 2.182 ± 0.034
3.68ThrGly: 3.68 ± 0.049
1.535ThrHis: 1.535 ± 0.028
2.346ThrIle: 2.346 ± 0.036
1.809ThrLys: 1.809 ± 0.036
5.76ThrLeu: 5.76 ± 0.063
1.077ThrMet: 1.077 ± 0.027
1.512ThrAsn: 1.512 ± 0.029
4.522ThrPro: 4.522 ± 0.068
1.823ThrGln: 1.823 ± 0.036
3.809ThrArg: 3.809 ± 0.045
4.527ThrSer: 4.527 ± 0.06
3.703ThrThr: 3.703 ± 0.062
3.919ThrVal: 3.919 ± 0.044
0.869ThrTrp: 0.869 ± 0.025
1.29ThrTyr: 1.29 ± 0.029
0.0ThrXaa: 0.0 ± 0.0
Val
6.732ValAla: 6.732 ± 0.07
1.195ValCys: 1.195 ± 0.03
4.131ValAsp: 4.131 ± 0.049
3.608ValGlu: 3.608 ± 0.045
2.537ValPhe: 2.537 ± 0.042
3.604ValGly: 3.604 ± 0.051
2.021ValHis: 2.021 ± 0.034
2.583ValIle: 2.583 ± 0.035
2.208ValLys: 2.208 ± 0.039
6.671ValLeu: 6.671 ± 0.065
1.152ValMet: 1.152 ± 0.027
1.789ValAsn: 1.789 ± 0.034
4.807ValPro: 4.807 ± 0.059
2.463ValGln: 2.463 ± 0.041
4.802ValArg: 4.802 ± 0.052
4.722ValSer: 4.722 ± 0.061
3.395ValThr: 3.395 ± 0.041
4.714ValVal: 4.714 ± 0.063
1.104ValTrp: 1.104 ± 0.025
1.607ValTyr: 1.607 ± 0.033
0.0ValXaa: 0.0 ± 0.0
Trp
1.479TrpAla: 1.479 ± 0.031
0.273TrpCys: 0.273 ± 0.013
1.055TrpAsp: 1.055 ± 0.03
0.85TrpGlu: 0.85 ± 0.02
0.548TrpPhe: 0.548 ± 0.019
0.792TrpGly: 0.792 ± 0.024
0.525TrpHis: 0.525 ± 0.018
0.645TrpIle: 0.645 ± 0.018
0.7TrpLys: 0.7 ± 0.02
1.417TrpLeu: 1.417 ± 0.028
0.368TrpMet: 0.368 ± 0.016
0.56TrpAsn: 0.56 ± 0.017
0.986TrpPro: 0.986 ± 0.025
0.549TrpGln: 0.549 ± 0.017
1.337TrpArg: 1.337 ± 0.027
1.133TrpSer: 1.133 ± 0.024
1.019TrpThr: 1.019 ± 0.021
0.859TrpVal: 0.859 ± 0.023
0.25TrpTrp: 0.25 ± 0.011
0.451TrpTyr: 0.451 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.396TyrAla: 2.396 ± 0.037
0.434TyrCys: 0.434 ± 0.017
1.548TyrAsp: 1.548 ± 0.032
1.276TyrGlu: 1.276 ± 0.029
0.914TyrPhe: 0.914 ± 0.023
1.63TyrGly: 1.63 ± 0.037
0.636TyrHis: 0.636 ± 0.017
1.011TyrIle: 1.011 ± 0.021
0.858TyrLys: 0.858 ± 0.023
2.277TyrLeu: 2.277 ± 0.036
0.536TyrMet: 0.536 ± 0.016
0.776TyrAsn: 0.776 ± 0.02
1.405TyrPro: 1.405 ± 0.027
0.751TyrGln: 0.751 ± 0.022
1.549TyrArg: 1.549 ± 0.034
1.568TyrSer: 1.568 ± 0.027
1.39TyrThr: 1.39 ± 0.032
1.511TyrVal: 1.511 ± 0.032
0.437TyrTrp: 0.437 ± 0.016
0.712TyrTyr: 0.712 ± 0.021
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.001XaaArg: 0.001 ± 0.001
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5290 proteins (1838300 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski