Amino acid dipepetide frequency for Baboon orthoreovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.041AlaAla: 3.041 ± 0.905
1.244AlaCys: 1.244 ± 0.374
3.455AlaAsp: 3.455 ± 0.48
2.764AlaGlu: 2.764 ± 0.669
2.488AlaPhe: 2.488 ± 0.766
2.903AlaGly: 2.903 ± 0.935
1.659AlaHis: 1.659 ± 0.358
4.699AlaIle: 4.699 ± 0.498
2.764AlaLys: 2.764 ± 0.675
6.358AlaLeu: 6.358 ± 1.35
1.244AlaMet: 1.244 ± 0.48
3.041AlaAsn: 3.041 ± 0.962
4.008AlaPro: 4.008 ± 0.984
1.935AlaGln: 1.935 ± 0.451
3.317AlaArg: 3.317 ± 0.945
4.285AlaSer: 4.285 ± 0.816
2.764AlaThr: 2.764 ± 0.631
3.041AlaVal: 3.041 ± 0.53
0.829AlaTrp: 0.829 ± 0.372
2.35AlaTyr: 2.35 ± 0.509
0.0AlaXaa: 0.0 ± 0.0
Cys
1.797CysAla: 1.797 ± 0.359
0.138CysCys: 0.138 ± 0.146
1.52CysAsp: 1.52 ± 0.492
0.553CysGlu: 0.553 ± 0.243
0.691CysPhe: 0.691 ± 0.28
0.691CysGly: 0.691 ± 0.27
0.415CysHis: 0.415 ± 0.24
0.829CysIle: 0.829 ± 0.406
0.415CysLys: 0.415 ± 0.304
1.244CysLeu: 1.244 ± 0.598
0.553CysMet: 0.553 ± 0.243
1.244CysAsn: 1.244 ± 0.322
0.691CysPro: 0.691 ± 0.335
0.415CysGln: 0.415 ± 0.248
0.415CysArg: 0.415 ± 0.246
0.691CysSer: 0.691 ± 0.329
0.968CysThr: 0.968 ± 0.329
0.968CysVal: 0.968 ± 0.375
0.138CysTrp: 0.138 ± 0.112
1.244CysTyr: 1.244 ± 0.466
0.0CysXaa: 0.0 ± 0.0
Asp
2.764AspAla: 2.764 ± 0.579
0.691AspCys: 0.691 ± 0.272
4.561AspAsp: 4.561 ± 0.609
3.732AspGlu: 3.732 ± 0.771
1.935AspPhe: 1.935 ± 0.408
3.455AspGly: 3.455 ± 0.632
2.35AspHis: 2.35 ± 0.44
3.87AspIle: 3.87 ± 0.85
2.626AspLys: 2.626 ± 0.649
4.838AspLeu: 4.838 ± 1.03
1.52AspMet: 1.52 ± 0.465
2.35AspAsn: 2.35 ± 0.459
2.626AspPro: 2.626 ± 0.351
2.211AspGln: 2.211 ± 0.637
3.732AspArg: 3.732 ± 0.635
4.838AspSer: 4.838 ± 0.505
4.147AspThr: 4.147 ± 0.722
6.496AspVal: 6.496 ± 0.608
1.106AspTrp: 1.106 ± 0.322
2.073AspTyr: 2.073 ± 0.784
0.0AspXaa: 0.0 ± 0.0
Glu
2.35GluAla: 2.35 ± 0.507
0.553GluCys: 0.553 ± 0.246
2.903GluAsp: 2.903 ± 0.532
2.073GluGlu: 2.073 ± 0.678
2.488GluPhe: 2.488 ± 0.605
1.797GluGly: 1.797 ± 0.507
1.935GluHis: 1.935 ± 0.53
4.147GluIle: 4.147 ± 0.86
2.073GluLys: 2.073 ± 0.538
4.838GluLeu: 4.838 ± 0.899
1.52GluMet: 1.52 ± 0.34
1.52GluAsn: 1.52 ± 0.413
1.659GluPro: 1.659 ± 0.469
1.935GluGln: 1.935 ± 0.415
1.382GluArg: 1.382 ± 0.306
3.455GluSer: 3.455 ± 0.477
2.35GluThr: 2.35 ± 0.758
4.423GluVal: 4.423 ± 1.094
0.553GluTrp: 0.553 ± 0.398
2.35GluTyr: 2.35 ± 0.81
0.0GluXaa: 0.0 ± 0.0
Phe
1.659PheAla: 1.659 ± 0.452
0.553PheCys: 0.553 ± 0.268
2.488PheAsp: 2.488 ± 0.669
2.35PheGlu: 2.35 ± 0.634
2.211PhePhe: 2.211 ± 0.651
2.903PheGly: 2.903 ± 0.52
0.829PheHis: 0.829 ± 0.349
3.317PheIle: 3.317 ± 0.659
1.797PheLys: 1.797 ± 0.385
3.179PheLeu: 3.179 ± 0.381
1.106PheMet: 1.106 ± 0.337
3.041PheAsn: 3.041 ± 0.439
1.659PhePro: 1.659 ± 0.325
2.073PheGln: 2.073 ± 0.423
0.691PheArg: 0.691 ± 0.297
4.423PheSer: 4.423 ± 0.902
1.797PheThr: 1.797 ± 0.277
2.903PheVal: 2.903 ± 0.631
0.553PheTrp: 0.553 ± 0.262
0.415PheTyr: 0.415 ± 0.157
0.0PheXaa: 0.0 ± 0.0
Gly
3.87GlyAla: 3.87 ± 0.869
0.691GlyCys: 0.691 ± 0.449
3.317GlyAsp: 3.317 ± 0.719
2.073GlyGlu: 2.073 ± 0.525
1.659GlyPhe: 1.659 ± 0.427
1.659GlyGly: 1.659 ± 0.472
0.276GlyHis: 0.276 ± 0.165
3.455GlyIle: 3.455 ± 0.822
2.488GlyLys: 2.488 ± 0.731
6.911GlyLeu: 6.911 ± 0.736
1.797GlyMet: 1.797 ± 0.343
2.903GlyAsn: 2.903 ± 0.609
1.382GlyPro: 1.382 ± 0.494
1.52GlyGln: 1.52 ± 0.476
2.626GlyArg: 2.626 ± 0.865
4.147GlySer: 4.147 ± 0.687
2.488GlyThr: 2.488 ± 0.564
4.008GlyVal: 4.008 ± 0.572
0.691GlyTrp: 0.691 ± 0.358
1.659GlyTyr: 1.659 ± 0.561
0.0GlyXaa: 0.0 ± 0.0
His
1.52HisAla: 1.52 ± 0.381
0.138HisCys: 0.138 ± 0.125
2.626HisAsp: 2.626 ± 0.501
0.829HisGlu: 0.829 ± 0.302
1.106HisPhe: 1.106 ± 0.439
1.382HisGly: 1.382 ± 0.414
1.52HisHis: 1.52 ± 0.776
1.106HisIle: 1.106 ± 0.228
1.935HisLys: 1.935 ± 0.612
2.488HisLeu: 2.488 ± 0.639
0.553HisMet: 0.553 ± 0.18
1.244HisAsn: 1.244 ± 0.42
0.968HisPro: 0.968 ± 0.291
1.244HisGln: 1.244 ± 0.333
0.968HisArg: 0.968 ± 0.409
1.935HisSer: 1.935 ± 0.387
2.073HisThr: 2.073 ± 0.588
1.106HisVal: 1.106 ± 0.47
0.276HisTrp: 0.276 ± 0.134
1.382HisTyr: 1.382 ± 0.311
0.0HisXaa: 0.0 ± 0.0
Ile
4.008IleAla: 4.008 ± 0.724
2.073IleCys: 2.073 ± 0.636
5.529IleAsp: 5.529 ± 0.649
3.041IleGlu: 3.041 ± 0.74
2.903IlePhe: 2.903 ± 0.711
4.147IleGly: 4.147 ± 0.402
2.488IleHis: 2.488 ± 0.364
5.252IleIle: 5.252 ± 0.732
4.285IleLys: 4.285 ± 1.103
5.39IleLeu: 5.39 ± 0.976
2.626IleMet: 2.626 ± 0.751
4.285IleAsn: 4.285 ± 0.597
4.008IlePro: 4.008 ± 0.529
0.968IleGln: 0.968 ± 0.29
4.423IleArg: 4.423 ± 0.467
6.358IleSer: 6.358 ± 0.773
4.423IleThr: 4.423 ± 0.735
3.594IleVal: 3.594 ± 0.622
0.415IleTrp: 0.415 ± 0.229
1.797IleTyr: 1.797 ± 0.494
0.0IleXaa: 0.0 ± 0.0
Lys
2.35LysAla: 2.35 ± 0.349
0.415LysCys: 0.415 ± 0.307
2.073LysAsp: 2.073 ± 0.608
3.317LysGlu: 3.317 ± 0.685
1.797LysPhe: 1.797 ± 0.286
2.211LysGly: 2.211 ± 0.645
1.52LysHis: 1.52 ± 0.821
4.285LysIle: 4.285 ± 0.745
1.52LysLys: 1.52 ± 0.259
4.976LysLeu: 4.976 ± 0.623
1.244LysMet: 1.244 ± 0.356
2.764LysAsn: 2.764 ± 0.481
1.659LysPro: 1.659 ± 0.342
1.52LysGln: 1.52 ± 0.498
2.488LysArg: 2.488 ± 0.597
4.423LysSer: 4.423 ± 0.278
1.935LysThr: 1.935 ± 0.478
2.211LysVal: 2.211 ± 0.641
1.106LysTrp: 1.106 ± 0.453
2.903LysTyr: 2.903 ± 0.667
0.0LysXaa: 0.0 ± 0.0
Leu
4.699LeuAla: 4.699 ± 0.74
1.659LeuCys: 1.659 ± 0.227
5.529LeuAsp: 5.529 ± 0.482
5.114LeuGlu: 5.114 ± 1.009
3.317LeuPhe: 3.317 ± 0.771
3.317LeuGly: 3.317 ± 0.448
3.041LeuHis: 3.041 ± 0.459
4.976LeuIle: 4.976 ± 0.402
4.976LeuLys: 4.976 ± 1.407
10.504LeuLeu: 10.504 ± 1.094
2.626LeuMet: 2.626 ± 0.396
8.017LeuAsn: 8.017 ± 0.84
5.805LeuPro: 5.805 ± 0.784
3.317LeuGln: 3.317 ± 1.082
5.114LeuArg: 5.114 ± 0.66
9.813LeuSer: 9.813 ± 1.272
6.358LeuThr: 6.358 ± 0.549
5.943LeuVal: 5.943 ± 0.903
0.968LeuTrp: 0.968 ± 0.374
3.732LeuTyr: 3.732 ± 0.636
0.0LeuXaa: 0.0 ± 0.0
Met
1.935MetAla: 1.935 ± 0.415
0.691MetCys: 0.691 ± 0.293
1.797MetAsp: 1.797 ± 0.633
1.52MetGlu: 1.52 ± 0.74
1.382MetPhe: 1.382 ± 0.45
1.52MetGly: 1.52 ± 0.525
0.691MetHis: 0.691 ± 0.348
1.659MetIle: 1.659 ± 0.315
1.382MetLys: 1.382 ± 0.556
2.35MetLeu: 2.35 ± 0.489
1.659MetMet: 1.659 ± 0.521
1.52MetAsn: 1.52 ± 0.443
1.797MetPro: 1.797 ± 0.492
0.553MetGln: 0.553 ± 0.341
1.382MetArg: 1.382 ± 0.519
3.179MetSer: 3.179 ± 0.696
1.935MetThr: 1.935 ± 0.439
1.935MetVal: 1.935 ± 0.437
0.415MetTrp: 0.415 ± 0.204
1.244MetTyr: 1.244 ± 0.253
0.0MetXaa: 0.0 ± 0.0
Asn
5.667AsnAla: 5.667 ± 1.591
0.829AsnCys: 0.829 ± 0.443
3.87AsnAsp: 3.87 ± 0.527
3.179AsnGlu: 3.179 ± 0.734
2.073AsnPhe: 2.073 ± 0.351
4.423AsnGly: 4.423 ± 0.69
1.659AsnHis: 1.659 ± 0.547
4.423AsnIle: 4.423 ± 0.787
2.35AsnLys: 2.35 ± 0.542
5.252AsnLeu: 5.252 ± 0.776
0.691AsnMet: 0.691 ± 0.222
3.455AsnAsn: 3.455 ± 0.648
1.935AsnPro: 1.935 ± 0.479
2.626AsnGln: 2.626 ± 0.459
2.211AsnArg: 2.211 ± 0.633
3.041AsnSer: 3.041 ± 0.339
2.903AsnThr: 2.903 ± 0.546
4.147AsnVal: 4.147 ± 0.68
1.52AsnTrp: 1.52 ± 0.479
2.903AsnTyr: 2.903 ± 0.709
0.0AsnXaa: 0.0 ± 0.0
Pro
2.35ProAla: 2.35 ± 0.821
0.415ProCys: 0.415 ± 0.245
2.626ProAsp: 2.626 ± 0.394
2.488ProGlu: 2.488 ± 0.331
2.35ProPhe: 2.35 ± 0.964
2.073ProGly: 2.073 ± 0.651
0.829ProHis: 0.829 ± 0.172
4.423ProIle: 4.423 ± 0.691
1.797ProLys: 1.797 ± 0.41
5.943ProLeu: 5.943 ± 1.216
1.106ProMet: 1.106 ± 0.648
2.764ProAsn: 2.764 ± 0.803
2.073ProPro: 2.073 ± 0.774
1.382ProGln: 1.382 ± 0.465
1.797ProArg: 1.797 ± 0.429
5.114ProSer: 5.114 ± 0.863
3.041ProThr: 3.041 ± 0.663
2.488ProVal: 2.488 ± 0.584
0.276ProTrp: 0.276 ± 0.256
2.35ProTyr: 2.35 ± 0.315
0.0ProXaa: 0.0 ± 0.0
Gln
1.935GlnAla: 1.935 ± 0.614
0.691GlnCys: 0.691 ± 0.399
1.797GlnAsp: 1.797 ± 0.415
0.691GlnGlu: 0.691 ± 0.303
2.073GlnPhe: 2.073 ± 0.585
1.244GlnGly: 1.244 ± 0.383
0.553GlnHis: 0.553 ± 0.271
4.008GlnIle: 4.008 ± 1.144
1.659GlnLys: 1.659 ± 0.386
6.082GlnLeu: 6.082 ± 0.98
1.382GlnMet: 1.382 ± 0.391
1.52GlnAsn: 1.52 ± 0.443
1.382GlnPro: 1.382 ± 0.33
1.935GlnGln: 1.935 ± 0.54
1.52GlnArg: 1.52 ± 0.54
0.968GlnSer: 0.968 ± 0.367
1.935GlnThr: 1.935 ± 0.461
2.073GlnVal: 2.073 ± 0.704
0.691GlnTrp: 0.691 ± 0.237
2.903GlnTyr: 2.903 ± 0.389
0.0GlnXaa: 0.0 ± 0.0
Arg
3.87ArgAla: 3.87 ± 0.625
0.829ArgCys: 0.829 ± 0.358
2.764ArgAsp: 2.764 ± 0.661
2.073ArgGlu: 2.073 ± 0.551
1.106ArgPhe: 1.106 ± 0.378
2.073ArgGly: 2.073 ± 0.518
1.659ArgHis: 1.659 ± 0.286
2.626ArgIle: 2.626 ± 0.572
1.797ArgLys: 1.797 ± 0.475
4.976ArgLeu: 4.976 ± 0.524
1.382ArgMet: 1.382 ± 0.226
2.764ArgAsn: 2.764 ± 0.348
2.073ArgPro: 2.073 ± 0.399
2.211ArgGln: 2.211 ± 0.551
3.455ArgArg: 3.455 ± 0.497
3.179ArgSer: 3.179 ± 0.656
2.073ArgThr: 2.073 ± 0.429
4.561ArgVal: 4.561 ± 0.474
0.691ArgTrp: 0.691 ± 0.247
3.041ArgTyr: 3.041 ± 0.709
0.0ArgXaa: 0.0 ± 0.0
Ser
6.082SerAla: 6.082 ± 0.828
0.553SerCys: 0.553 ± 0.282
5.114SerAsp: 5.114 ± 1.112
3.179SerGlu: 3.179 ± 0.574
3.317SerPhe: 3.317 ± 0.522
4.976SerGly: 4.976 ± 0.929
0.691SerHis: 0.691 ± 0.241
5.805SerIle: 5.805 ± 0.747
3.179SerLys: 3.179 ± 0.657
5.252SerLeu: 5.252 ± 0.747
3.317SerMet: 3.317 ± 1.005
4.423SerAsn: 4.423 ± 1.257
4.008SerPro: 4.008 ± 0.355
3.732SerGln: 3.732 ± 0.717
6.22SerArg: 6.22 ± 0.965
7.187SerSer: 7.187 ± 1.23
5.252SerThr: 5.252 ± 0.708
5.114SerVal: 5.114 ± 0.978
1.244SerTrp: 1.244 ± 0.338
3.87SerTyr: 3.87 ± 0.682
0.0SerXaa: 0.0 ± 0.0
Thr
3.041ThrAla: 3.041 ± 0.589
1.244ThrCys: 1.244 ± 0.263
2.764ThrAsp: 2.764 ± 0.61
2.626ThrGlu: 2.626 ± 0.605
2.35ThrPhe: 2.35 ± 0.503
2.488ThrGly: 2.488 ± 0.529
1.52ThrHis: 1.52 ± 0.613
4.561ThrIle: 4.561 ± 1.114
1.797ThrLys: 1.797 ± 0.501
5.805ThrLeu: 5.805 ± 0.397
1.935ThrMet: 1.935 ± 0.675
3.732ThrAsn: 3.732 ± 0.786
3.594ThrPro: 3.594 ± 1.04
2.626ThrGln: 2.626 ± 0.386
1.935ThrArg: 1.935 ± 0.388
4.699ThrSer: 4.699 ± 0.681
4.561ThrThr: 4.561 ± 0.854
2.211ThrVal: 2.211 ± 0.926
1.382ThrTrp: 1.382 ± 0.568
2.488ThrTyr: 2.488 ± 0.92
0.0ThrXaa: 0.0 ± 0.0
Val
3.179ValAla: 3.179 ± 0.738
0.968ValCys: 0.968 ± 0.271
3.041ValAsp: 3.041 ± 0.768
2.626ValGlu: 2.626 ± 0.733
2.211ValPhe: 2.211 ± 0.5
2.903ValGly: 2.903 ± 0.607
1.659ValHis: 1.659 ± 0.279
4.008ValIle: 4.008 ± 0.504
4.147ValLys: 4.147 ± 0.736
5.943ValLeu: 5.943 ± 0.799
2.488ValMet: 2.488 ± 0.593
4.561ValAsn: 4.561 ± 0.32
3.594ValPro: 3.594 ± 0.694
2.488ValGln: 2.488 ± 0.784
3.594ValArg: 3.594 ± 0.62
5.943ValSer: 5.943 ± 0.864
2.903ValThr: 2.903 ± 0.792
2.488ValVal: 2.488 ± 0.533
0.968ValTrp: 0.968 ± 0.42
2.488ValTyr: 2.488 ± 0.725
0.0ValXaa: 0.0 ± 0.0
Trp
0.553TrpAla: 0.553 ± 0.411
0.553TrpCys: 0.553 ± 0.144
0.691TrpAsp: 0.691 ± 0.195
0.553TrpGlu: 0.553 ± 0.31
0.553TrpPhe: 0.553 ± 0.207
0.0TrpGly: 0.0 ± 0.0
0.138TrpHis: 0.138 ± 0.125
1.244TrpIle: 1.244 ± 0.476
0.829TrpLys: 0.829 ± 0.299
1.797TrpLeu: 1.797 ± 0.515
0.691TrpMet: 0.691 ± 0.252
0.968TrpAsn: 0.968 ± 0.243
0.829TrpPro: 0.829 ± 0.27
0.829TrpGln: 0.829 ± 0.333
0.415TrpArg: 0.415 ± 0.166
1.659TrpSer: 1.659 ± 0.401
0.415TrpThr: 0.415 ± 0.247
0.691TrpVal: 0.691 ± 0.307
0.0TrpTrp: 0.0 ± 0.0
0.829TrpTyr: 0.829 ± 0.338
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.52TyrAla: 1.52 ± 0.454
0.691TyrCys: 0.691 ± 0.216
3.455TyrAsp: 3.455 ± 0.651
1.52TyrGlu: 1.52 ± 0.471
1.935TyrPhe: 1.935 ± 0.474
3.455TyrGly: 3.455 ± 0.553
0.968TyrHis: 0.968 ± 0.394
3.317TyrIle: 3.317 ± 0.631
2.903TyrLys: 2.903 ± 0.878
4.699TyrLeu: 4.699 ± 0.711
0.968TyrMet: 0.968 ± 0.362
3.041TyrAsn: 3.041 ± 0.494
1.935TyrPro: 1.935 ± 0.395
1.52TyrGln: 1.52 ± 0.438
1.52TyrArg: 1.52 ± 0.707
3.179TyrSer: 3.179 ± 0.776
3.041TyrThr: 3.041 ± 0.617
1.935TyrVal: 1.935 ± 0.604
0.415TyrTrp: 0.415 ± 0.293
2.488TyrTyr: 2.488 ± 0.62
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (7236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski