Amino acid dipepetide frequency for Hippeastrum latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.407AlaAla: 9.407 ± 2.844
0.362AlaCys: 0.362 ± 0.189
3.256AlaAsp: 3.256 ± 1.407
6.874AlaGlu: 6.874 ± 1.477
3.256AlaPhe: 3.256 ± 1.043
3.618AlaGly: 3.618 ± 1.055
2.533AlaHis: 2.533 ± 1.969
5.427AlaIle: 5.427 ± 2.39
6.874AlaLys: 6.874 ± 1.482
5.427AlaLeu: 5.427 ± 1.793
1.809AlaMet: 1.809 ± 0.685
3.618AlaAsn: 3.618 ± 1.353
2.533AlaPro: 2.533 ± 0.996
2.171AlaGln: 2.171 ± 1.131
5.789AlaArg: 5.789 ± 0.813
5.789AlaSer: 5.789 ± 0.816
2.894AlaThr: 2.894 ± 1.894
7.236AlaVal: 7.236 ± 1.72
0.362AlaTrp: 0.362 ± 0.189
2.894AlaTyr: 2.894 ± 0.906
0.0AlaXaa: 0.0 ± 0.0
Cys
3.256CysAla: 3.256 ± 1.383
1.447CysCys: 1.447 ± 1.88
0.724CysAsp: 0.724 ± 0.965
0.724CysGlu: 0.724 ± 0.377
3.256CysPhe: 3.256 ± 0.969
2.171CysGly: 2.171 ± 1.022
0.362CysHis: 0.362 ± 1.07
1.447CysIle: 1.447 ± 0.907
1.447CysLys: 1.447 ± 1.48
3.618CysLeu: 3.618 ± 1.235
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.447CysPro: 1.447 ± 1.629
1.447CysGln: 1.447 ± 1.629
3.618CysArg: 3.618 ± 1.065
0.724CysSer: 0.724 ± 0.377
3.256CysThr: 3.256 ± 1.697
4.342CysVal: 4.342 ± 2.264
0.362CysTrp: 0.362 ± 0.189
0.724CysTyr: 0.724 ± 0.965
0.0CysXaa: 0.0 ± 0.0
Asp
4.342AspAla: 4.342 ± 1.875
1.809AspCys: 1.809 ± 0.569
1.447AspAsp: 1.447 ± 0.486
5.427AspGlu: 5.427 ± 1.853
1.447AspPhe: 1.447 ± 0.754
2.894AspGly: 2.894 ± 1.246
1.085AspHis: 1.085 ± 0.541
3.618AspIle: 3.618 ± 0.96
2.171AspLys: 2.171 ± 1.131
2.894AspLeu: 2.894 ± 1.007
1.085AspMet: 1.085 ± 0.469
3.256AspAsn: 3.256 ± 1.063
3.618AspPro: 3.618 ± 2.075
1.809AspGln: 1.809 ± 1.359
1.447AspArg: 1.447 ± 0.486
2.894AspSer: 2.894 ± 1.451
2.171AspThr: 2.171 ± 1.131
1.809AspVal: 1.809 ± 0.943
0.724AspTrp: 0.724 ± 0.524
1.809AspTyr: 1.809 ± 0.881
0.0AspXaa: 0.0 ± 0.0
Glu
5.065GluAla: 5.065 ± 0.859
1.809GluCys: 1.809 ± 0.618
2.533GluAsp: 2.533 ± 0.844
3.256GluGlu: 3.256 ± 0.685
4.703GluPhe: 4.703 ± 0.963
3.256GluGly: 3.256 ± 1.319
2.894GluHis: 2.894 ± 1.329
4.703GluIle: 4.703 ± 1.016
3.618GluLys: 3.618 ± 0.832
9.045GluLeu: 9.045 ± 2.626
1.809GluMet: 1.809 ± 0.725
4.342GluAsn: 4.342 ± 1.137
2.171GluPro: 2.171 ± 1.215
2.171GluGln: 2.171 ± 1.131
4.703GluArg: 4.703 ± 1.865
2.533GluSer: 2.533 ± 1.169
1.447GluThr: 1.447 ± 0.754
6.151GluVal: 6.151 ± 1.57
1.085GluTrp: 1.085 ± 0.469
3.256GluTyr: 3.256 ± 0.905
0.0GluXaa: 0.0 ± 0.0
Phe
4.342PheAla: 4.342 ± 1.293
0.362PheCys: 0.362 ± 0.189
6.874PheAsp: 6.874 ± 1.344
6.512PheGlu: 6.512 ± 1.336
1.809PhePhe: 1.809 ± 0.709
2.533PheGly: 2.533 ± 1.074
0.362PheHis: 0.362 ± 0.189
3.256PheIle: 3.256 ± 1.775
3.618PheLys: 3.618 ± 0.96
5.789PheLeu: 5.789 ± 0.96
1.085PheMet: 1.085 ± 0.566
1.447PheAsn: 1.447 ± 0.847
0.362PhePro: 0.362 ± 1.01
1.085PheGln: 1.085 ± 0.469
2.171PheArg: 2.171 ± 1.13
3.618PheSer: 3.618 ± 0.82
2.533PheThr: 2.533 ± 0.869
2.533PheVal: 2.533 ± 1.074
0.724PheTrp: 0.724 ± 0.965
1.447PheTyr: 1.447 ± 0.907
0.0PheXaa: 0.0 ± 0.0
Gly
2.171GlyAla: 2.171 ± 0.535
1.085GlyCys: 1.085 ± 0.904
4.342GlyAsp: 4.342 ± 0.725
3.618GlyGlu: 3.618 ± 1.112
2.171GlyPhe: 2.171 ± 2.393
3.256GlyGly: 3.256 ± 1.062
1.447GlyHis: 1.447 ± 0.907
3.618GlyIle: 3.618 ± 1.49
4.342GlyLys: 4.342 ± 1.459
3.98GlyLeu: 3.98 ± 1.045
2.533GlyMet: 2.533 ± 1.32
1.447GlyAsn: 1.447 ± 0.754
1.447GlyPro: 1.447 ± 1.065
2.533GlyGln: 2.533 ± 0.875
5.065GlyArg: 5.065 ± 0.941
5.065GlySer: 5.065 ± 1.737
3.98GlyThr: 3.98 ± 2.019
6.151GlyVal: 6.151 ± 1.031
1.085GlyTrp: 1.085 ± 0.566
1.447GlyTyr: 1.447 ± 0.754
0.0GlyXaa: 0.0 ± 0.0
His
1.447HisAla: 1.447 ± 0.907
1.085HisCys: 1.085 ± 0.541
0.724HisAsp: 0.724 ± 0.377
1.085HisGlu: 1.085 ± 0.566
1.809HisPhe: 1.809 ± 1.028
0.724HisGly: 0.724 ± 0.94
0.724HisHis: 0.724 ± 0.965
0.362HisIle: 0.362 ± 1.07
1.447HisLys: 1.447 ± 1.966
2.894HisLeu: 2.894 ± 1.508
1.085HisMet: 1.085 ± 0.469
1.085HisAsn: 1.085 ± 1.668
0.724HisPro: 0.724 ± 0.94
0.362HisGln: 0.362 ± 0.189
1.809HisArg: 1.809 ± 1.028
3.618HisSer: 3.618 ± 1.061
0.362HisThr: 0.362 ± 0.699
1.447HisVal: 1.447 ± 0.754
0.0HisTrp: 0.0 ± 0.0
0.724HisTyr: 0.724 ± 0.596
0.0HisXaa: 0.0 ± 0.0
Ile
3.98IleAla: 3.98 ± 3.828
3.618IleCys: 3.618 ± 1.235
2.533IleAsp: 2.533 ± 1.107
4.342IleGlu: 4.342 ± 1.262
1.809IlePhe: 1.809 ± 0.948
3.98IleGly: 3.98 ± 2.189
0.724IleHis: 0.724 ± 0.377
1.447IleIle: 1.447 ± 1.524
1.809IleLys: 1.809 ± 0.943
4.342IleLeu: 4.342 ± 1.035
1.809IleMet: 1.809 ± 0.569
0.724IleAsn: 0.724 ± 0.377
2.533IlePro: 2.533 ± 1.92
1.447IleGln: 1.447 ± 0.486
4.342IleArg: 4.342 ± 0.92
4.342IleSer: 4.342 ± 2.094
3.256IleThr: 3.256 ± 2.444
3.618IleVal: 3.618 ± 1.011
0.362IleTrp: 0.362 ± 0.189
2.533IleTyr: 2.533 ± 0.964
0.0IleXaa: 0.0 ± 0.0
Lys
3.98LysAla: 3.98 ± 1.024
0.362LysCys: 0.362 ± 0.189
2.171LysAsp: 2.171 ± 0.535
2.171LysGlu: 2.171 ± 1.082
3.98LysPhe: 3.98 ± 2.074
2.171LysGly: 2.171 ± 0.73
1.085LysHis: 1.085 ± 0.566
2.894LysIle: 2.894 ± 1.007
3.618LysLys: 3.618 ± 1.885
8.321LysLeu: 8.321 ± 1.184
1.085LysMet: 1.085 ± 0.469
1.809LysAsn: 1.809 ± 0.943
2.894LysPro: 2.894 ± 0.973
1.447LysGln: 1.447 ± 0.486
5.789LysArg: 5.789 ± 2.153
3.256LysSer: 3.256 ± 0.685
4.342LysThr: 4.342 ± 0.689
4.342LysVal: 4.342 ± 1.39
1.447LysTrp: 1.447 ± 0.847
1.447LysTyr: 1.447 ± 0.754
0.0LysXaa: 0.0 ± 0.0
Leu
6.151LeuAla: 6.151 ± 0.622
5.427LeuCys: 5.427 ± 2.143
4.342LeuAsp: 4.342 ± 1.459
6.874LeuGlu: 6.874 ± 2.388
2.533LeuPhe: 2.533 ± 0.919
6.512LeuGly: 6.512 ± 1.014
2.171LeuHis: 2.171 ± 0.73
4.703LeuIle: 4.703 ± 1.939
5.789LeuLys: 5.789 ± 2.014
6.151LeuLeu: 6.151 ± 2.433
2.171LeuMet: 2.171 ± 1.306
3.618LeuAsn: 3.618 ± 1.061
3.256LeuPro: 3.256 ± 1.383
3.618LeuGln: 3.618 ± 1.359
6.151LeuArg: 6.151 ± 1.112
5.789LeuSer: 5.789 ± 1.941
2.894LeuThr: 2.894 ± 1.21
7.598LeuVal: 7.598 ± 2.144
1.085LeuTrp: 1.085 ± 0.904
2.894LeuTyr: 2.894 ± 0.973
0.0LeuXaa: 0.0 ± 0.0
Met
4.703MetAla: 4.703 ± 2.414
2.171MetCys: 2.171 ± 1.131
1.809MetAsp: 1.809 ± 0.618
1.809MetGlu: 1.809 ± 0.569
1.085MetPhe: 1.085 ± 0.566
1.809MetGly: 1.809 ± 0.569
0.0MetHis: 0.0 ± 0.0
0.724MetIle: 0.724 ± 0.377
1.085MetLys: 1.085 ± 0.469
1.809MetLeu: 1.809 ± 0.976
0.362MetMet: 0.362 ± 0.189
0.724MetAsn: 0.724 ± 0.377
0.724MetPro: 0.724 ± 0.94
1.809MetGln: 1.809 ± 0.943
1.809MetArg: 1.809 ± 1.098
0.724MetSer: 0.724 ± 0.377
0.362MetThr: 0.362 ± 0.189
1.085MetVal: 1.085 ± 0.566
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.256AsnAla: 3.256 ± 0.685
1.809AsnCys: 1.809 ± 1.167
0.362AsnAsp: 0.362 ± 0.189
1.085AsnGlu: 1.085 ± 0.469
2.894AsnPhe: 2.894 ± 1.508
1.085AsnGly: 1.085 ± 0.566
0.724AsnHis: 0.724 ± 0.524
1.085AsnIle: 1.085 ± 0.566
3.98AsnLys: 3.98 ± 1.586
1.809AsnLeu: 1.809 ± 0.569
1.447AsnMet: 1.447 ± 0.486
1.809AsnAsn: 1.809 ± 0.569
2.171AsnPro: 2.171 ± 0.938
0.724AsnGln: 0.724 ± 0.524
2.171AsnArg: 2.171 ± 0.86
1.447AsnSer: 1.447 ± 1.022
2.171AsnThr: 2.171 ± 0.695
2.894AsnVal: 2.894 ± 0.906
0.362AsnTrp: 0.362 ± 0.189
1.809AsnTyr: 1.809 ± 0.943
0.0AsnXaa: 0.0 ± 0.0
Pro
2.894ProAla: 2.894 ± 1.213
2.171ProCys: 2.171 ± 0.799
2.894ProAsp: 2.894 ± 1.246
3.256ProGlu: 3.256 ± 0.685
2.894ProPhe: 2.894 ± 2.047
4.342ProGly: 4.342 ± 2.185
1.447ProHis: 1.447 ± 2.435
1.085ProIle: 1.085 ± 0.541
2.171ProLys: 2.171 ± 1.571
3.256ProLeu: 3.256 ± 2.198
0.724ProMet: 0.724 ± 0.377
0.724ProAsn: 0.724 ± 1.019
2.533ProPro: 2.533 ± 3.213
1.447ProGln: 1.447 ± 0.486
2.533ProArg: 2.533 ± 0.869
2.533ProSer: 2.533 ± 2.449
2.533ProThr: 2.533 ± 1.494
1.447ProVal: 1.447 ± 0.486
0.362ProTrp: 0.362 ± 0.189
0.362ProTyr: 0.362 ± 0.189
0.0ProXaa: 0.0 ± 0.0
Gln
2.533GlnAla: 2.533 ± 1.132
1.085GlnCys: 1.085 ± 0.904
1.447GlnAsp: 1.447 ± 1.306
3.618GlnGlu: 3.618 ± 1.359
1.447GlnPhe: 1.447 ± 0.754
2.171GlnGly: 2.171 ± 0.535
1.447GlnHis: 1.447 ± 0.754
2.171GlnIle: 2.171 ± 0.535
1.809GlnLys: 1.809 ± 0.943
2.533GlnLeu: 2.533 ± 0.844
0.724GlnMet: 0.724 ± 0.377
0.362GlnAsn: 0.362 ± 0.189
1.809GlnPro: 1.809 ± 0.606
1.085GlnGln: 1.085 ± 0.862
1.809GlnArg: 1.809 ± 0.569
2.533GlnSer: 2.533 ± 1.124
0.724GlnThr: 0.724 ± 1.019
1.085GlnVal: 1.085 ± 0.862
0.362GlnTrp: 0.362 ± 0.189
1.085GlnTyr: 1.085 ± 0.469
0.0GlnXaa: 0.0 ± 0.0
Arg
6.512ArgAla: 6.512 ± 1.463
2.533ArgCys: 2.533 ± 3.283
3.618ArgAsp: 3.618 ± 1.353
6.151ArgGlu: 6.151 ± 1.511
5.427ArgPhe: 5.427 ± 1.092
5.427ArgGly: 5.427 ± 1.202
1.447ArgHis: 1.447 ± 1.022
3.98ArgIle: 3.98 ± 0.857
2.171ArgLys: 2.171 ± 0.73
4.703ArgLeu: 4.703 ± 2.101
1.809ArgMet: 1.809 ± 0.569
1.809ArgAsn: 1.809 ± 0.569
2.894ArgPro: 2.894 ± 2.054
1.085ArgGln: 1.085 ± 0.566
3.98ArgArg: 3.98 ± 3.342
4.703ArgSer: 4.703 ± 1.535
3.256ArgThr: 3.256 ± 1.845
3.256ArgVal: 3.256 ± 3.139
1.085ArgTrp: 1.085 ± 0.566
2.171ArgTyr: 2.171 ± 1.131
0.0ArgXaa: 0.0 ± 0.0
Ser
5.789SerAla: 5.789 ± 1.533
1.809SerCys: 1.809 ± 0.618
2.533SerAsp: 2.533 ± 1.494
4.703SerGlu: 4.703 ± 1.454
3.618SerPhe: 3.618 ± 1.03
4.703SerGly: 4.703 ± 1.459
1.447SerHis: 1.447 ± 0.754
4.342SerIle: 4.342 ± 2.37
3.618SerLys: 3.618 ± 1.359
5.065SerLeu: 5.065 ± 1.689
1.447SerMet: 1.447 ± 0.58
2.894SerAsn: 2.894 ± 1.007
2.171SerPro: 2.171 ± 0.799
2.171SerGln: 2.171 ± 0.535
5.065SerArg: 5.065 ± 1.834
2.894SerSer: 2.894 ± 1.439
3.256SerThr: 3.256 ± 1.75
3.256SerVal: 3.256 ± 0.756
0.0SerTrp: 0.0 ± 0.0
3.618SerTyr: 3.618 ± 2.029
0.0SerXaa: 0.0 ± 0.0
Thr
3.98ThrAla: 3.98 ± 1.138
0.724ThrCys: 0.724 ± 1.411
1.447ThrAsp: 1.447 ± 0.754
2.894ThrGlu: 2.894 ± 0.581
3.618ThrPhe: 3.618 ± 0.82
2.894ThrGly: 2.894 ± 2.047
1.085ThrHis: 1.085 ± 0.469
2.171ThrIle: 2.171 ± 0.747
3.256ThrLys: 3.256 ± 1.838
5.065ThrLeu: 5.065 ± 2.007
1.809ThrMet: 1.809 ± 0.583
1.809ThrAsn: 1.809 ± 0.976
2.171ThrPro: 2.171 ± 1.271
1.447ThrGln: 1.447 ± 0.754
2.894ThrArg: 2.894 ± 1.285
3.98ThrSer: 3.98 ± 1.134
1.447ThrThr: 1.447 ± 1.778
2.533ThrVal: 2.533 ± 0.937
0.724ThrTrp: 0.724 ± 0.524
1.809ThrTyr: 1.809 ± 1.028
0.0ThrXaa: 0.0 ± 0.0
Val
5.789ValAla: 5.789 ± 1.369
3.256ValCys: 3.256 ± 0.685
3.618ValAsp: 3.618 ± 0.898
5.065ValGlu: 5.065 ± 0.859
2.533ValPhe: 2.533 ± 1.074
4.703ValGly: 4.703 ± 0.756
2.171ValHis: 2.171 ± 0.799
3.618ValIle: 3.618 ± 1.055
2.533ValLys: 2.533 ± 0.964
7.598ValLeu: 7.598 ± 1.772
1.085ValMet: 1.085 ± 0.732
1.809ValAsn: 1.809 ± 0.847
3.98ValPro: 3.98 ± 1.134
3.256ValGln: 3.256 ± 1.932
3.618ValArg: 3.618 ± 1.223
5.427ValSer: 5.427 ± 1.524
2.894ValThr: 2.894 ± 0.973
5.789ValVal: 5.789 ± 2.741
0.0ValTrp: 0.0 ± 0.0
1.447ValTyr: 1.447 ± 0.847
0.0ValXaa: 0.0 ± 0.0
Trp
0.362TrpAla: 0.362 ± 0.632
0.724TrpCys: 0.724 ± 0.377
0.0TrpAsp: 0.0 ± 0.0
0.362TrpGlu: 0.362 ± 0.632
0.724TrpPhe: 0.724 ± 0.377
0.724TrpGly: 0.724 ± 0.965
0.362TrpHis: 0.362 ± 0.189
0.0TrpIle: 0.0 ± 0.0
1.085TrpLys: 1.085 ± 0.469
1.809TrpLeu: 1.809 ± 0.943
0.0TrpMet: 0.0 ± 0.0
0.724TrpAsn: 0.724 ± 0.524
0.362TrpPro: 0.362 ± 0.189
0.0TrpGln: 0.0 ± 0.0
0.724TrpArg: 0.724 ± 0.377
0.362TrpSer: 0.362 ± 0.189
0.724TrpThr: 0.724 ± 1.672
1.447TrpVal: 1.447 ± 0.754
0.362TrpTrp: 0.362 ± 1.07
0.362TrpTyr: 0.362 ± 0.189
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.171TyrAla: 2.171 ± 0.86
0.724TyrCys: 0.724 ± 0.524
1.085TyrAsp: 1.085 ± 0.566
0.724TyrGlu: 0.724 ± 0.377
1.447TyrPhe: 1.447 ± 0.645
1.809TyrGly: 1.809 ± 0.943
0.0TyrHis: 0.0 ± 0.0
2.894TyrIle: 2.894 ± 0.873
2.171TyrLys: 2.171 ± 0.888
3.618TyrLeu: 3.618 ± 1.353
0.362TyrMet: 0.362 ± 0.189
1.085TyrAsn: 1.085 ± 1.077
1.809TyrPro: 1.809 ± 0.847
0.724TyrGln: 0.724 ± 0.94
2.533TyrArg: 2.533 ± 0.964
2.171TyrSer: 2.171 ± 1.131
3.256TyrThr: 3.256 ± 1.933
2.533TyrVal: 2.533 ± 0.806
0.724TyrTrp: 0.724 ± 0.524
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2765 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski