Amino acid dipepetide frequency for Elaphomyces granulatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.627AlaAla: 7.627 ± 0.057	0.943AlaCys: 0.943 ± 0.018	3.94AlaAsp: 3.94 ± 0.034	4.765AlaGlu: 4.765 ± 0.045	2.985AlaPhe: 2.985 ± 0.034	5.071AlaGly: 5.071 ± 0.043	1.602AlaHis: 1.602 ± 0.024	4.288AlaIle: 4.288 ± 0.039	3.677AlaLys: 3.677 ± 0.039	7.449AlaLeu: 7.449 ± 0.062	1.686AlaMet: 1.686 ± 0.024	2.793AlaAsn: 2.793 ± 0.029	3.977AlaPro: 3.977 ± 0.046	2.905AlaGln: 2.905 ± 0.028	4.733AlaArg: 4.733 ± 0.041	6.924AlaSer: 6.924 ± 0.047	4.723AlaThr: 4.723 ± 0.041	5.136AlaVal: 5.136 ± 0.042	0.97AlaTrp: 0.97 ± 0.022	1.972AlaTyr: 1.972 ± 0.028	0.001AlaXaa: 0.001 ± 0.001
Cys	0.796CysAla: 0.796 ± 0.015	0.237CysCys: 0.237 ± 0.008	0.637CysAsp: 0.637 ± 0.016	0.646CysGlu: 0.646 ± 0.016	0.525CysPhe: 0.525 ± 0.013	0.893CysGly: 0.893 ± 0.017	0.352CysHis: 0.352 ± 0.009	0.683CysIle: 0.683 ± 0.015	0.522CysLys: 0.522 ± 0.013	1.307CysLeu: 1.307 ± 0.023	0.243CysMet: 0.243 ± 0.008	0.416CysAsn: 0.416 ± 0.011	0.65CysPro: 0.65 ± 0.015	0.487CysGln: 0.487 ± 0.012	0.798CysArg: 0.798 ± 0.017	0.941CysSer: 0.941 ± 0.018	0.615CysThr: 0.615 ± 0.014	0.743CysVal: 0.743 ± 0.015	0.209CysTrp: 0.209 ± 0.008	0.354CysTyr: 0.354 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.208AspAla: 4.208 ± 0.041	0.66AspCys: 0.66 ± 0.013	4.352AspAsp: 4.352 ± 0.055	4.446AspGlu: 4.446 ± 0.048	2.229AspPhe: 2.229 ± 0.022	4.067AspGly: 4.067 ± 0.041	1.387AspHis: 1.387 ± 0.023	3.427AspIle: 3.427 ± 0.035	2.268AspLys: 2.268 ± 0.027	5.33AspLeu: 5.33 ± 0.038	1.179AspMet: 1.179 ± 0.019	2.008AspAsn: 2.008 ± 0.022	3.437AspPro: 3.437 ± 0.036	1.952AspGln: 1.952 ± 0.025	3.366AspArg: 3.366 ± 0.044	4.397AspSer: 4.397 ± 0.043	2.87AspThr: 2.87 ± 0.029	3.644AspVal: 3.644 ± 0.033	0.822AspTrp: 0.822 ± 0.015	1.543AspTyr: 1.543 ± 0.023	0.001AspXaa: 0.001 ± 0.0
Glu	5.09GluAla: 5.09 ± 0.048	0.623GluCys: 0.623 ± 0.014	4.206GluAsp: 4.206 ± 0.045	5.538GluGlu: 5.538 ± 0.068	2.053GluPhe: 2.053 ± 0.023	3.594GluGly: 3.594 ± 0.035	1.338GluHis: 1.338 ± 0.02	3.396GluIle: 3.396 ± 0.036	3.873GluLys: 3.873 ± 0.047	5.409GluLeu: 5.409 ± 0.048	1.454GluMet: 1.454 ± 0.022	2.517GluAsn: 2.517 ± 0.027	2.678GluPro: 2.678 ± 0.037	2.481GluGln: 2.481 ± 0.034	4.254GluArg: 4.254 ± 0.048	4.538GluSer: 4.538 ± 0.041	3.496GluThr: 3.496 ± 0.032	3.525GluVal: 3.525 ± 0.034	0.887GluTrp: 0.887 ± 0.018	1.654GluTyr: 1.654 ± 0.02	0.001GluXaa: 0.001 ± 0.0
Phe	2.811PheAla: 2.811 ± 0.029	0.59PheCys: 0.59 ± 0.013	2.326PheAsp: 2.326 ± 0.027	2.173PheGlu: 2.173 ± 0.028	1.622PhePhe: 1.622 ± 0.023	2.715PheGly: 2.715 ± 0.034	0.942PheHis: 0.942 ± 0.014	1.878PheIle: 1.878 ± 0.027	1.535PheLys: 1.535 ± 0.022	3.72PheLeu: 3.72 ± 0.036	0.732PheMet: 0.732 ± 0.015	1.458PheAsn: 1.458 ± 0.022	2.058PhePro: 2.058 ± 0.026	1.485PheGln: 1.485 ± 0.023	2.189PheArg: 2.189 ± 0.027	3.217PheSer: 3.217 ± 0.029	2.064PheThr: 2.064 ± 0.026	2.299PheVal: 2.299 ± 0.032	0.564PheTrp: 0.564 ± 0.014	1.091PheTyr: 1.091 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	4.511GlyAla: 4.511 ± 0.037	0.803GlyCys: 0.803 ± 0.015	3.697GlyAsp: 3.697 ± 0.037	3.617GlyGlu: 3.617 ± 0.037	2.669GlyPhe: 2.669 ± 0.031	5.23GlyGly: 5.23 ± 0.054	1.672GlyHis: 1.672 ± 0.024	3.661GlyIle: 3.661 ± 0.039	3.438GlyLys: 3.438 ± 0.041	5.889GlyLeu: 5.889 ± 0.051	1.438GlyMet: 1.438 ± 0.022	2.58GlyAsn: 2.58 ± 0.031	3.29GlyPro: 3.29 ± 0.042	2.463GlyGln: 2.463 ± 0.025	4.266GlyArg: 4.266 ± 0.039	5.678GlySer: 5.678 ± 0.048	3.691GlyThr: 3.691 ± 0.032	4.07GlyVal: 4.07 ± 0.037	1.021GlyTrp: 1.021 ± 0.018	2.012GlyTyr: 2.012 ± 0.028	0.002GlyXaa: 0.002 ± 0.001
His	1.679HisAla: 1.679 ± 0.025	0.33HisCys: 0.33 ± 0.011	1.332HisAsp: 1.332 ± 0.021	1.319HisGlu: 1.319 ± 0.019	0.943HisPhe: 0.943 ± 0.017	1.652HisGly: 1.652 ± 0.022	0.9HisHis: 0.9 ± 0.018	1.271HisIle: 1.271 ± 0.018	0.868HisLys: 0.868 ± 0.015	2.366HisLeu: 2.366 ± 0.026	0.433HisMet: 0.433 ± 0.01	0.823HisAsn: 0.823 ± 0.015	1.78HisPro: 1.78 ± 0.021	1.075HisGln: 1.075 ± 0.023	1.69HisArg: 1.69 ± 0.022	1.988HisSer: 1.988 ± 0.028	1.227HisThr: 1.227 ± 0.022	1.408HisVal: 1.408 ± 0.022	0.326HisTrp: 0.326 ± 0.011	0.686HisTyr: 0.686 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.08IleAla: 4.08 ± 0.04	0.79IleCys: 0.79 ± 0.014	3.079IleAsp: 3.079 ± 0.035	3.102IleGlu: 3.102 ± 0.029	2.158IlePhe: 2.158 ± 0.03	3.207IleGly: 3.207 ± 0.04	1.313IleHis: 1.313 ± 0.019	2.71IleIle: 2.71 ± 0.029	2.326IleLys: 2.326 ± 0.026	5.041IleLeu: 5.041 ± 0.042	1.004IleMet: 1.004 ± 0.017	1.923IleAsn: 1.923 ± 0.026	3.269IlePro: 3.269 ± 0.033	2.042IleGln: 2.042 ± 0.024	3.193IleArg: 3.193 ± 0.031	4.46IleSer: 4.46 ± 0.034	2.839IleThr: 2.839 ± 0.026	3.231IleVal: 3.231 ± 0.037	0.727IleTrp: 0.727 ± 0.015	1.495IleTyr: 1.495 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	3.971LysAla: 3.971 ± 0.044	0.501LysCys: 0.501 ± 0.012	2.762LysAsp: 2.762 ± 0.031	3.491LysGlu: 3.491 ± 0.046	1.496LysPhe: 1.496 ± 0.021	2.932LysGly: 2.932 ± 0.03	1.092LysHis: 1.092 ± 0.018	2.489LysIle: 2.489 ± 0.03	3.163LysLys: 3.163 ± 0.05	4.287LysLeu: 4.287 ± 0.045	1.068LysMet: 1.068 ± 0.021	1.796LysAsn: 1.796 ± 0.021	2.597LysPro: 2.597 ± 0.03	1.91LysGln: 1.91 ± 0.027	3.693LysArg: 3.693 ± 0.04	3.602LysSer: 3.602 ± 0.029	2.724LysThr: 2.724 ± 0.032	2.751LysVal: 2.751 ± 0.028	0.645LysTrp: 0.645 ± 0.013	1.369LysTyr: 1.369 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	7.31LeuAla: 7.31 ± 0.057	1.222LeuCys: 1.222 ± 0.021	5.536LeuAsp: 5.536 ± 0.047	5.897LeuGlu: 5.897 ± 0.052	3.418LeuPhe: 3.418 ± 0.035	5.882LeuGly: 5.882 ± 0.05	2.307LeuHis: 2.307 ± 0.026	4.244LeuIle: 4.244 ± 0.043	4.525LeuLys: 4.525 ± 0.037	8.914LeuLeu: 8.914 ± 0.074	1.712LeuMet: 1.712 ± 0.023	3.41LeuAsn: 3.41 ± 0.03	5.682LeuPro: 5.682 ± 0.044	4.235LeuGln: 4.235 ± 0.044	6.295LeuArg: 6.295 ± 0.048	8.069LeuSer: 8.069 ± 0.056	4.956LeuThr: 4.956 ± 0.039	5.45LeuVal: 5.45 ± 0.05	1.175LeuTrp: 1.175 ± 0.021	2.44LeuTyr: 2.44 ± 0.034	0.001LeuXaa: 0.001 ± 0.001
Met	1.981MetAla: 1.981 ± 0.024	0.22MetCys: 0.22 ± 0.008	1.197MetAsp: 1.197 ± 0.02	1.318MetGlu: 1.318 ± 0.019	0.707MetPhe: 0.707 ± 0.015	1.302MetGly: 1.302 ± 0.021	0.435MetHis: 0.435 ± 0.012	1.012MetIle: 1.012 ± 0.016	0.999MetLys: 0.999 ± 0.02	1.824MetLeu: 1.824 ± 0.025	0.526MetMet: 0.526 ± 0.013	0.784MetAsn: 0.784 ± 0.015	1.1MetPro: 1.1 ± 0.018	0.822MetGln: 0.822 ± 0.015	1.213MetArg: 1.213 ± 0.019	1.755MetSer: 1.755 ± 0.025	1.213MetThr: 1.213 ± 0.019	1.235MetVal: 1.235 ± 0.02	0.251MetTrp: 0.251 ± 0.008	0.532MetTyr: 0.532 ± 0.017	0.001MetXaa: 0.001 ± 0.0
Asn	2.959AsnAla: 2.959 ± 0.03	0.469AsnCys: 0.469 ± 0.011	2.11AsnAsp: 2.11 ± 0.024	2.137AsnGlu: 2.137 ± 0.024	1.407AsnPhe: 1.407 ± 0.018	2.96AsnGly: 2.96 ± 0.033	0.888AsnHis: 0.888 ± 0.019	2.231AsnIle: 2.231 ± 0.029	1.567AsnLys: 1.567 ± 0.024	3.544AsnLeu: 3.544 ± 0.036	0.799AsnMet: 0.799 ± 0.014	1.649AsnAsn: 1.649 ± 0.029	2.557AsnPro: 2.557 ± 0.028	1.394AsnGln: 1.394 ± 0.022	2.225AsnArg: 2.225 ± 0.025	3.018AsnSer: 3.018 ± 0.03	2.103AsnThr: 2.103 ± 0.024	2.421AsnVal: 2.421 ± 0.028	0.519AsnTrp: 0.519 ± 0.013	1.051AsnTyr: 1.051 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.518ProAla: 4.518 ± 0.052	0.523ProCys: 0.523 ± 0.014	3.255ProAsp: 3.255 ± 0.036	3.698ProGlu: 3.698 ± 0.04	2.135ProPhe: 2.135 ± 0.026	3.764ProGly: 3.764 ± 0.044	1.33ProHis: 1.33 ± 0.021	2.67ProIle: 2.67 ± 0.027	2.556ProLys: 2.556 ± 0.033	5.024ProLeu: 5.024 ± 0.041	0.98ProMet: 0.98 ± 0.016	2.309ProAsn: 2.309 ± 0.027	5.43ProPro: 5.43 ± 0.094	2.489ProGln: 2.489 ± 0.04	3.535ProArg: 3.535 ± 0.042	6.501ProSer: 6.501 ± 0.078	3.829ProThr: 3.829 ± 0.041	3.53ProVal: 3.53 ± 0.04	0.67ProTrp: 0.67 ± 0.015	1.479ProTyr: 1.479 ± 0.023	0.002ProXaa: 0.002 ± 0.001
Gln	3.14GlnAla: 3.14 ± 0.029	0.439GlnCys: 0.439 ± 0.011	2.053GlnAsp: 2.053 ± 0.025	2.531GlnGlu: 2.531 ± 0.034	1.345GlnPhe: 1.345 ± 0.022	2.481GlnGly: 2.481 ± 0.033	1.075GlnHis: 1.075 ± 0.021	2.018GlnIle: 2.018 ± 0.023	2.079GlnLys: 2.079 ± 0.021	3.639GlnLeu: 3.639 ± 0.042	0.865GlnMet: 0.865 ± 0.016	1.659GlnAsn: 1.659 ± 0.024	2.475GlnPro: 2.475 ± 0.042	2.619GlnGln: 2.619 ± 0.077	2.907GlnArg: 2.907 ± 0.027	3.342GlnSer: 3.342 ± 0.043	2.322GlnThr: 2.322 ± 0.023	2.182GlnVal: 2.182 ± 0.024	0.531GlnTrp: 0.531 ± 0.012	1.098GlnTyr: 1.098 ± 0.019	0.001GlnXaa: 0.001 ± 0.001
Arg	4.61ArgAla: 4.61 ± 0.043	0.761ArgCys: 0.761 ± 0.017	3.646ArgAsp: 3.646 ± 0.042	4.203ArgGlu: 4.203 ± 0.043	2.322ArgPhe: 2.322 ± 0.03	3.836ArgGly: 3.836 ± 0.041	1.69ArgHis: 1.69 ± 0.024	3.223ArgIle: 3.223 ± 0.035	3.779ArgLys: 3.779 ± 0.036	6.069ArgLeu: 6.069 ± 0.045	1.325ArgMet: 1.325 ± 0.019	2.486ArgAsn: 2.486 ± 0.03	3.707ArgPro: 3.707 ± 0.043	2.834ArgGln: 2.834 ± 0.029	5.645ArgArg: 5.645 ± 0.06	5.323ArgSer: 5.323 ± 0.048	3.413ArgThr: 3.413 ± 0.036	3.523ArgVal: 3.523 ± 0.028	0.909ArgTrp: 0.909 ± 0.015	1.733ArgTyr: 1.733 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	6.298SerAla: 6.298 ± 0.049	0.867SerCys: 0.867 ± 0.015	4.388SerAsp: 4.388 ± 0.04	4.34SerGlu: 4.34 ± 0.04	3.205SerPhe: 3.205 ± 0.031	5.606SerGly: 5.606 ± 0.053	2.109SerHis: 2.109 ± 0.026	4.367SerIle: 4.367 ± 0.042	3.935SerLys: 3.935 ± 0.041	7.929SerLeu: 7.929 ± 0.054	1.703SerMet: 1.703 ± 0.022	3.388SerAsn: 3.388 ± 0.039	5.992SerPro: 5.992 ± 0.081	3.567SerGln: 3.567 ± 0.035	5.656SerArg: 5.656 ± 0.05	9.708SerSer: 9.708 ± 0.097	5.706SerThr: 5.706 ± 0.052	4.816SerVal: 4.816 ± 0.039	1.078SerTrp: 1.078 ± 0.019	2.066SerTyr: 2.066 ± 0.022	0.001SerXaa: 0.001 ± 0.0
Thr	4.823ThrAla: 4.823 ± 0.041	0.699ThrCys: 0.699 ± 0.014	2.867ThrAsp: 2.867 ± 0.027	3.081ThrGlu: 3.081 ± 0.03	2.18ThrPhe: 2.18 ± 0.025	3.96ThrGly: 3.96 ± 0.038	1.204ThrHis: 1.204 ± 0.02	3.078ThrIle: 3.078 ± 0.035	2.513ThrLys: 2.513 ± 0.031	5.363ThrLeu: 5.363 ± 0.047	1.115ThrMet: 1.115 ± 0.016	2.034ThrAsn: 2.034 ± 0.024	4.058ThrPro: 4.058 ± 0.053	1.998ThrGln: 1.998 ± 0.026	3.195ThrArg: 3.195 ± 0.029	5.378ThrSer: 5.378 ± 0.041	3.908ThrThr: 3.908 ± 0.041	3.715ThrVal: 3.715 ± 0.036	0.735ThrTrp: 0.735 ± 0.016	1.468ThrTyr: 1.468 ± 0.021	0.001ThrXaa: 0.001 ± 0.0
Val	4.853ValAla: 4.853 ± 0.042	0.786ValCys: 0.786 ± 0.017	3.769ValAsp: 3.769 ± 0.037	3.941ValGlu: 3.941 ± 0.038	2.411ValPhe: 2.411 ± 0.03	3.792ValGly: 3.792 ± 0.037	1.376ValHis: 1.376 ± 0.022	3.167ValIle: 3.167 ± 0.035	2.863ValLys: 2.863 ± 0.03	5.57ValLeu: 5.57 ± 0.046	1.255ValMet: 1.255 ± 0.017	2.343ValAsn: 2.343 ± 0.027	3.448ValPro: 3.448 ± 0.036	2.359ValGln: 2.359 ± 0.027	3.514ValArg: 3.514 ± 0.03	4.827ValSer: 4.827 ± 0.039	3.438ValThr: 3.438 ± 0.036	4.155ValVal: 4.155 ± 0.042	0.784ValTrp: 0.784 ± 0.016	1.606ValTyr: 1.606 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.974TrpAla: 0.974 ± 0.019	0.188TrpCys: 0.188 ± 0.007	0.846TrpAsp: 0.846 ± 0.016	0.821TrpGlu: 0.821 ± 0.015	0.483TrpPhe: 0.483 ± 0.011	0.841TrpGly: 0.841 ± 0.02	0.326TrpHis: 0.326 ± 0.01	0.739TrpIle: 0.739 ± 0.016	0.789TrpLys: 0.789 ± 0.014	1.285TrpLeu: 1.285 ± 0.019	0.339TrpMet: 0.339 ± 0.009	0.603TrpAsn: 0.603 ± 0.013	0.544TrpPro: 0.544 ± 0.014	0.516TrpGln: 0.516 ± 0.012	0.957TrpArg: 0.957 ± 0.018	0.987TrpSer: 0.987 ± 0.017	0.793TrpThr: 0.793 ± 0.015	0.799TrpVal: 0.799 ± 0.018	0.25TrpTrp: 0.25 ± 0.009	0.369TrpTyr: 0.369 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.924TyrAla: 1.924 ± 0.024	0.403TyrCys: 0.403 ± 0.012	1.596TyrAsp: 1.596 ± 0.021	1.543TyrGlu: 1.543 ± 0.023	1.178TyrPhe: 1.178 ± 0.021	1.912TyrGly: 1.912 ± 0.027	0.759TyrHis: 0.759 ± 0.015	1.435TyrIle: 1.435 ± 0.02	1.064TyrLys: 1.064 ± 0.021	2.717TyrLeu: 2.717 ± 0.03	0.565TyrMet: 0.565 ± 0.014	1.032TyrAsn: 1.032 ± 0.015	1.5TyrPro: 1.5 ± 0.024	1.166TyrGln: 1.166 ± 0.021	1.711TyrArg: 1.711 ± 0.023	2.07TyrSer: 2.07 ± 0.027	1.443TyrThr: 1.443 ± 0.02	1.622TyrVal: 1.622 ± 0.021	0.376TyrTrp: 0.376 ± 0.011	0.884TyrTyr: 0.884 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.0	0.002XaaSer: 0.002 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.089XaaXaa: 0.089 ± 0.021

Statistics based on 7169 proteins (3610934 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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