Amino acid dipepetide frequency for Rosellinia necatrix (White root-rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.087AlaAla: 11.087 ± 0.065	1.114AlaCys: 1.114 ± 0.017	4.813AlaAsp: 4.813 ± 0.031	5.263AlaGlu: 5.263 ± 0.04	3.219AlaPhe: 3.219 ± 0.024	6.694AlaGly: 6.694 ± 0.045	1.921AlaHis: 1.921 ± 0.019	4.36AlaIle: 4.36 ± 0.034	3.867AlaLys: 3.867 ± 0.033	8.235AlaLeu: 8.235 ± 0.046	1.975AlaMet: 1.975 ± 0.017	3.052AlaAsn: 3.052 ± 0.024	5.082AlaPro: 5.082 ± 0.038	3.355AlaGln: 3.355 ± 0.029	5.812AlaArg: 5.812 ± 0.038	7.444AlaSer: 7.444 ± 0.043	5.761AlaThr: 5.761 ± 0.038	5.873AlaVal: 5.873 ± 0.041	1.258AlaTrp: 1.258 ± 0.016	2.269AlaTyr: 2.269 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.997CysAla: 0.997 ± 0.014	0.236CysCys: 0.236 ± 0.007	0.679CysAsp: 0.679 ± 0.013	0.6CysGlu: 0.6 ± 0.012	0.48CysPhe: 0.48 ± 0.011	0.922CysGly: 0.922 ± 0.014	0.337CysHis: 0.337 ± 0.008	0.669CysIle: 0.669 ± 0.012	0.44CysLys: 0.44 ± 0.01	1.212CysLeu: 1.212 ± 0.019	0.242CysMet: 0.242 ± 0.006	0.41CysAsn: 0.41 ± 0.01	0.669CysPro: 0.669 ± 0.012	0.438CysGln: 0.438 ± 0.009	0.797CysArg: 0.797 ± 0.014	0.85CysSer: 0.85 ± 0.012	0.653CysThr: 0.653 ± 0.012	0.783CysVal: 0.783 ± 0.011	0.205CysTrp: 0.205 ± 0.006	0.348CysTyr: 0.348 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.271AspAla: 5.271 ± 0.038	0.646AspCys: 0.646 ± 0.011	4.844AspAsp: 4.844 ± 0.053	4.456AspGlu: 4.456 ± 0.035	2.145AspPhe: 2.145 ± 0.022	4.724AspGly: 4.724 ± 0.036	1.292AspHis: 1.292 ± 0.017	3.141AspIle: 3.141 ± 0.024	2.254AspLys: 2.254 ± 0.021	4.997AspLeu: 4.997 ± 0.037	1.279AspMet: 1.279 ± 0.014	1.975AspAsn: 1.975 ± 0.022	3.449AspPro: 3.449 ± 0.028	1.812AspGln: 1.812 ± 0.02	3.271AspArg: 3.271 ± 0.032	4.019AspSer: 4.019 ± 0.032	3.015AspThr: 3.015 ± 0.027	3.821AspVal: 3.821 ± 0.024	0.893AspTrp: 0.893 ± 0.013	1.608AspTyr: 1.608 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.533GluAla: 5.533 ± 0.038	0.628GluCys: 0.628 ± 0.011	4.005GluAsp: 4.005 ± 0.033	4.895GluGlu: 4.895 ± 0.044	1.902GluPhe: 1.902 ± 0.02	3.851GluGly: 3.851 ± 0.031	1.338GluHis: 1.338 ± 0.018	2.956GluIle: 2.956 ± 0.028	3.21GluLys: 3.21 ± 0.03	5.113GluLeu: 5.113 ± 0.04	1.364GluMet: 1.364 ± 0.017	2.139GluAsn: 2.139 ± 0.023	2.868GluPro: 2.868 ± 0.026	2.253GluGln: 2.253 ± 0.028	3.972GluArg: 3.972 ± 0.033	3.985GluSer: 3.985 ± 0.033	3.316GluThr: 3.316 ± 0.026	3.384GluVal: 3.384 ± 0.024	0.866GluTrp: 0.866 ± 0.013	1.581GluTyr: 1.581 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.106PheAla: 3.106 ± 0.024	0.496PheCys: 0.496 ± 0.011	2.273PheAsp: 2.273 ± 0.02	2.048PheGlu: 2.048 ± 0.019	1.508PhePhe: 1.508 ± 0.021	2.825PheGly: 2.825 ± 0.027	0.883PheHis: 0.883 ± 0.012	1.697PheIle: 1.697 ± 0.023	1.366PheLys: 1.366 ± 0.017	3.285PheLeu: 3.285 ± 0.032	0.707PheMet: 0.707 ± 0.011	1.361PheAsn: 1.361 ± 0.017	1.928PhePro: 1.928 ± 0.019	1.332PheGln: 1.332 ± 0.016	2.076PheArg: 2.076 ± 0.019	2.79PheSer: 2.79 ± 0.025	2.048PheThr: 2.048 ± 0.019	2.346PheVal: 2.346 ± 0.021	0.622PheTrp: 0.622 ± 0.012	1.064PheTyr: 1.064 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.272GlyAla: 6.272 ± 0.044	0.879GlyCys: 0.879 ± 0.013	4.221GlyAsp: 4.221 ± 0.034	3.85GlyGlu: 3.85 ± 0.029	2.792GlyPhe: 2.792 ± 0.024	7.168GlyGly: 7.168 ± 0.071	1.849GlyHis: 1.849 ± 0.022	3.479GlyIle: 3.479 ± 0.031	3.214GlyLys: 3.214 ± 0.027	6.246GlyLeu: 6.246 ± 0.034	1.504GlyMet: 1.504 ± 0.014	2.661GlyAsn: 2.661 ± 0.025	3.663GlyPro: 3.663 ± 0.031	2.526GlyGln: 2.526 ± 0.023	4.765GlyArg: 4.765 ± 0.037	5.958GlySer: 5.958 ± 0.043	4.121GlyThr: 4.121 ± 0.033	4.582GlyVal: 4.582 ± 0.031	1.196GlyTrp: 1.196 ± 0.014	2.144GlyTyr: 2.144 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	1.947HisAla: 1.947 ± 0.021	0.323HisCys: 0.323 ± 0.008	1.44HisAsp: 1.44 ± 0.017	1.341HisGlu: 1.341 ± 0.017	0.884HisPhe: 0.884 ± 0.012	1.897HisGly: 1.897 ± 0.022	0.971HisHis: 0.971 ± 0.022	1.185HisIle: 1.185 ± 0.014	0.86HisLys: 0.86 ± 0.013	2.188HisLeu: 2.188 ± 0.021	0.508HisMet: 0.508 ± 0.011	0.838HisAsn: 0.838 ± 0.012	1.671HisPro: 1.671 ± 0.021	1.026HisGln: 1.026 ± 0.016	1.609HisArg: 1.609 ± 0.019	1.758HisSer: 1.758 ± 0.022	1.245HisThr: 1.245 ± 0.014	1.46HisVal: 1.46 ± 0.016	0.332HisTrp: 0.332 ± 0.008	0.708HisTyr: 0.708 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.219IleAla: 4.219 ± 0.033	0.693IleCys: 0.693 ± 0.011	2.915IleAsp: 2.915 ± 0.024	2.766IleGlu: 2.766 ± 0.024	1.821IlePhe: 1.821 ± 0.02	3.184IleGly: 3.184 ± 0.027	1.168IleHis: 1.168 ± 0.016	2.442IleIle: 2.442 ± 0.025	2.02IleLys: 2.02 ± 0.019	4.354IleLeu: 4.354 ± 0.036	0.987IleMet: 0.987 ± 0.015	1.758IleAsn: 1.758 ± 0.021	3.059IlePro: 3.059 ± 0.023	1.873IleGln: 1.873 ± 0.017	2.923IleArg: 2.923 ± 0.023	3.703IleSer: 3.703 ± 0.025	2.843IleThr: 2.843 ± 0.026	3.115IleVal: 3.115 ± 0.025	0.71IleTrp: 0.71 ± 0.014	1.313IleTyr: 1.313 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.015LysAla: 4.015 ± 0.035	0.445LysCys: 0.445 ± 0.01	2.49LysAsp: 2.49 ± 0.026	2.884LysGlu: 2.884 ± 0.032	1.323LysPhe: 1.323 ± 0.016	2.804LysGly: 2.804 ± 0.023	1.036LysHis: 1.036 ± 0.012	2.086LysIle: 2.086 ± 0.021	2.916LysLys: 2.916 ± 0.044	3.767LysLeu: 3.767 ± 0.034	0.913LysMet: 0.913 ± 0.012	1.575LysAsn: 1.575 ± 0.015	2.569LysPro: 2.569 ± 0.028	1.626LysGln: 1.626 ± 0.021	3.18LysArg: 3.18 ± 0.028	3.12LysSer: 3.12 ± 0.029	2.625LysThr: 2.625 ± 0.026	2.454LysVal: 2.454 ± 0.023	0.616LysTrp: 0.616 ± 0.012	1.263LysTyr: 1.263 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	8.395LeuAla: 8.395 ± 0.048	1.169LeuCys: 1.169 ± 0.015	5.202LeuAsp: 5.202 ± 0.032	5.293LeuGlu: 5.293 ± 0.036	3.195LeuPhe: 3.195 ± 0.025	6.205LeuGly: 6.205 ± 0.036	2.187LeuHis: 2.187 ± 0.026	3.749LeuIle: 3.749 ± 0.03	3.773LeuLys: 3.773 ± 0.029	8.359LeuLeu: 8.359 ± 0.061	1.64LeuMet: 1.64 ± 0.02	2.964LeuAsn: 2.964 ± 0.027	5.469LeuPro: 5.469 ± 0.03	3.591LeuGln: 3.591 ± 0.028	6.094LeuArg: 6.094 ± 0.041	7.024LeuSer: 7.024 ± 0.042	4.651LeuThr: 4.651 ± 0.033	5.593LeuVal: 5.593 ± 0.045	1.242LeuTrp: 1.242 ± 0.019	2.307LeuTyr: 2.307 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.265MetAla: 2.265 ± 0.02	0.224MetCys: 0.224 ± 0.007	1.192MetAsp: 1.192 ± 0.014	1.154MetGlu: 1.154 ± 0.015	0.672MetPhe: 0.672 ± 0.01	1.44MetGly: 1.44 ± 0.018	0.448MetHis: 0.448 ± 0.008	0.916MetIle: 0.916 ± 0.013	0.932MetLys: 0.932 ± 0.014	1.75MetLeu: 1.75 ± 0.017	0.581MetMet: 0.581 ± 0.011	0.761MetAsn: 0.761 ± 0.012	1.296MetPro: 1.296 ± 0.016	0.795MetGln: 0.795 ± 0.014	1.323MetArg: 1.323 ± 0.015	1.726MetSer: 1.726 ± 0.016	1.278MetThr: 1.278 ± 0.014	1.223MetVal: 1.223 ± 0.016	0.246MetTrp: 0.246 ± 0.007	0.482MetTyr: 0.482 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.144AsnAla: 3.144 ± 0.025	0.442AsnCys: 0.442 ± 0.008	2.029AsnAsp: 2.029 ± 0.019	1.929AsnGlu: 1.929 ± 0.019	1.277AsnPhe: 1.277 ± 0.016	2.976AsnGly: 2.976 ± 0.03	0.84AsnHis: 0.84 ± 0.014	1.971AsnIle: 1.971 ± 0.021	1.426AsnLys: 1.426 ± 0.019	3.068AsnLeu: 3.068 ± 0.026	0.836AsnMet: 0.836 ± 0.014	1.66AsnAsn: 1.66 ± 0.028	2.405AsnPro: 2.405 ± 0.024	1.311AsnGln: 1.311 ± 0.021	1.949AsnArg: 1.949 ± 0.02	2.667AsnSer: 2.667 ± 0.028	2.236AsnThr: 2.236 ± 0.022	2.143AsnVal: 2.143 ± 0.022	0.542AsnTrp: 0.542 ± 0.011	1.028AsnTyr: 1.028 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.647ProAla: 5.647 ± 0.043	0.531ProCys: 0.531 ± 0.01	3.39ProAsp: 3.39 ± 0.028	3.683ProGlu: 3.683 ± 0.027	2.006ProPhe: 2.006 ± 0.018	4.384ProGly: 4.384 ± 0.036	1.391ProHis: 1.391 ± 0.016	2.597ProIle: 2.597 ± 0.023	2.442ProLys: 2.442 ± 0.024	4.84ProLeu: 4.84 ± 0.034	1.069ProMet: 1.069 ± 0.016	2.267ProAsn: 2.267 ± 0.024	5.606ProPro: 5.606 ± 0.07	2.416ProGln: 2.416 ± 0.03	3.847ProArg: 3.847 ± 0.034	5.952ProSer: 5.952 ± 0.045	4.162ProThr: 4.162 ± 0.036	3.498ProVal: 3.498 ± 0.026	0.781ProTrp: 0.781 ± 0.012	1.515ProTyr: 1.515 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.442GlnAla: 3.442 ± 0.029	0.443GlnCys: 0.443 ± 0.01	2.017GlnAsp: 2.017 ± 0.021	2.147GlnGlu: 2.147 ± 0.025	1.254GlnPhe: 1.254 ± 0.014	2.413GlnGly: 2.413 ± 0.023	1.091GlnHis: 1.091 ± 0.017	1.814GlnIle: 1.814 ± 0.019	1.742GlnLys: 1.742 ± 0.018	3.368GlnLeu: 3.368 ± 0.028	0.808GlnMet: 0.808 ± 0.014	1.429GlnAsn: 1.429 ± 0.017	2.61GlnPro: 2.61 ± 0.032	2.642GlnGln: 2.642 ± 0.07	2.628GlnArg: 2.628 ± 0.022	2.89GlnSer: 2.89 ± 0.027	2.19GlnThr: 2.19 ± 0.019	2.089GlnVal: 2.089 ± 0.02	0.574GlnTrp: 0.574 ± 0.01	1.106GlnTyr: 1.106 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.51ArgAla: 5.51 ± 0.037	0.756ArgCys: 0.756 ± 0.011	3.882ArgAsp: 3.882 ± 0.03	3.95ArgGlu: 3.95 ± 0.033	2.218ArgPhe: 2.218 ± 0.02	4.346ArgGly: 4.346 ± 0.037	1.755ArgHis: 1.755 ± 0.02	2.991ArgIle: 2.991 ± 0.022	3.158ArgLys: 3.158 ± 0.027	5.817ArgLeu: 5.817 ± 0.036	1.336ArgMet: 1.336 ± 0.014	2.27ArgAsn: 2.27 ± 0.021	3.952ArgPro: 3.952 ± 0.034	2.728ArgGln: 2.728 ± 0.023	5.805ArgArg: 5.805 ± 0.049	4.739ArgSer: 4.739 ± 0.035	3.326ArgThr: 3.326 ± 0.025	3.653ArgVal: 3.653 ± 0.027	1.026ArgTrp: 1.026 ± 0.014	1.748ArgTyr: 1.748 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.724SerAla: 6.724 ± 0.04	0.857SerCys: 0.857 ± 0.014	4.126SerAsp: 4.126 ± 0.034	3.83SerGlu: 3.83 ± 0.027	2.857SerPhe: 2.857 ± 0.025	5.714SerGly: 5.714 ± 0.041	1.928SerHis: 1.928 ± 0.022	3.828SerIle: 3.828 ± 0.029	3.258SerLys: 3.258 ± 0.029	6.939SerLeu: 6.939 ± 0.04	1.613SerMet: 1.613 ± 0.018	2.844SerAsn: 2.844 ± 0.027	5.571SerPro: 5.571 ± 0.055	3.115SerGln: 3.115 ± 0.03	5.177SerArg: 5.177 ± 0.039	8.501SerSer: 8.501 ± 0.074	5.261SerThr: 5.261 ± 0.044	4.421SerVal: 4.421 ± 0.028	1.129SerTrp: 1.129 ± 0.015	2.056SerTyr: 2.056 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.588ThrAla: 5.588 ± 0.031	0.719ThrCys: 0.719 ± 0.012	2.866ThrAsp: 2.866 ± 0.023	2.994ThrGlu: 2.994 ± 0.024	2.117ThrPhe: 2.117 ± 0.019	4.254ThrGly: 4.254 ± 0.029	1.262ThrHis: 1.262 ± 0.015	3.074ThrIle: 3.074 ± 0.025	2.487ThrLys: 2.487 ± 0.025	5.054ThrLeu: 5.054 ± 0.033	1.193ThrMet: 1.193 ± 0.015	2.125ThrAsn: 2.125 ± 0.024	4.403ThrPro: 4.403 ± 0.034	2.039ThrGln: 2.039 ± 0.022	3.335ThrArg: 3.335 ± 0.024	5.1ThrSer: 5.1 ± 0.04	4.837ThrThr: 4.837 ± 0.052	3.649ThrVal: 3.649 ± 0.03	0.862ThrTrp: 0.862 ± 0.013	1.597ThrTyr: 1.597 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.804ValAla: 5.804 ± 0.036	0.779ValCys: 0.779 ± 0.012	3.842ValAsp: 3.842 ± 0.027	3.707ValGlu: 3.707 ± 0.033	2.409ValPhe: 2.409 ± 0.025	4.213ValGly: 4.213 ± 0.033	1.383ValHis: 1.383 ± 0.016	2.85ValIle: 2.85 ± 0.026	2.602ValLys: 2.602 ± 0.023	5.575ValLeu: 5.575 ± 0.039	1.224ValMet: 1.224 ± 0.015	2.156ValAsn: 2.156 ± 0.02	3.57ValPro: 3.57 ± 0.023	2.19ValGln: 2.19 ± 0.021	3.689ValArg: 3.689 ± 0.029	4.549ValSer: 4.549 ± 0.031	3.544ValThr: 3.544 ± 0.036	4.588ValVal: 4.588 ± 0.04	0.881ValTrp: 0.881 ± 0.014	1.714ValTyr: 1.714 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.268TrpAla: 1.268 ± 0.018	0.188TrpCys: 0.188 ± 0.006	0.988TrpAsp: 0.988 ± 0.014	0.849TrpGlu: 0.849 ± 0.015	0.54TrpPhe: 0.54 ± 0.011	0.977TrpGly: 0.977 ± 0.015	0.364TrpHis: 0.364 ± 0.008	0.721TrpIle: 0.721 ± 0.012	0.716TrpLys: 0.716 ± 0.01	1.368TrpLeu: 1.368 ± 0.018	0.341TrpMet: 0.341 ± 0.007	0.599TrpAsn: 0.599 ± 0.009	0.652TrpPro: 0.652 ± 0.012	0.563TrpGln: 0.563 ± 0.012	1.024TrpArg: 1.024 ± 0.013	1.015TrpSer: 1.015 ± 0.014	0.877TrpThr: 0.877 ± 0.012	0.937TrpVal: 0.937 ± 0.014	0.269TrpTrp: 0.269 ± 0.008	0.438TrpTyr: 0.438 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.219TyrAla: 2.219 ± 0.022	0.399TyrCys: 0.399 ± 0.008	1.695TyrAsp: 1.695 ± 0.017	1.519TyrGlu: 1.519 ± 0.018	1.143TyrPhe: 1.143 ± 0.013	2.099TyrGly: 2.099 ± 0.023	0.748TyrHis: 0.748 ± 0.011	1.339TyrIle: 1.339 ± 0.015	1.023TyrLys: 1.023 ± 0.013	2.568TyrLeu: 2.568 ± 0.024	0.583TyrMet: 0.583 ± 0.01	1.039TyrAsn: 1.039 ± 0.013	1.532TyrPro: 1.532 ± 0.026	1.068TyrGln: 1.068 ± 0.016	1.69TyrArg: 1.69 ± 0.019	1.959TyrSer: 1.959 ± 0.018	1.565TyrThr: 1.565 ± 0.017	1.657TyrVal: 1.657 ± 0.016	0.442TyrTrp: 0.442 ± 0.009	0.964TyrTyr: 0.964 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12440 proteins (5726925 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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