Amino acid dipepetide frequency for Bacteroides finegoldii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.525AlaAla: 5.525 ± 0.087
0.942AlaCys: 0.942 ± 0.026
4.154AlaAsp: 4.154 ± 0.055
4.655AlaGlu: 4.655 ± 0.068
3.024AlaPhe: 3.024 ± 0.048
4.863AlaGly: 4.863 ± 0.067
1.198AlaHis: 1.198 ± 0.03
4.74AlaIle: 4.74 ± 0.067
4.181AlaLys: 4.181 ± 0.061
6.398AlaLeu: 6.398 ± 0.09
1.926AlaMet: 1.926 ± 0.041
3.349AlaAsn: 3.349 ± 0.06
2.271AlaPro: 2.271 ± 0.038
2.618AlaGln: 2.618 ± 0.05
2.906AlaArg: 2.906 ± 0.051
4.223AlaSer: 4.223 ± 0.056
3.962AlaThr: 3.962 ± 0.062
4.557AlaVal: 4.557 ± 0.069
0.824AlaTrp: 0.824 ± 0.026
2.928AlaTyr: 2.928 ± 0.045
0.0AlaXaa: 0.0 ± 0.0
Cys
0.734CysAla: 0.734 ± 0.026
0.23CysCys: 0.23 ± 0.013
0.608CysAsp: 0.608 ± 0.02
0.684CysGlu: 0.684 ± 0.024
0.634CysPhe: 0.634 ± 0.023
0.958CysGly: 0.958 ± 0.032
0.261CysHis: 0.261 ± 0.013
0.945CysIle: 0.945 ± 0.025
0.68CysLys: 0.68 ± 0.023
1.093CysLeu: 1.093 ± 0.031
0.318CysMet: 0.318 ± 0.015
0.526CysAsn: 0.526 ± 0.02
0.502CysPro: 0.502 ± 0.02
0.363CysGln: 0.363 ± 0.016
0.588CysArg: 0.588 ± 0.022
0.789CysSer: 0.789 ± 0.026
0.685CysThr: 0.685 ± 0.023
0.689CysVal: 0.689 ± 0.025
0.161CysTrp: 0.161 ± 0.011
0.566CysTyr: 0.566 ± 0.021
0.0CysXaa: 0.0 ± 0.0
Asp
3.726AspAla: 3.726 ± 0.058
0.624AspCys: 0.624 ± 0.021
2.782AspAsp: 2.782 ± 0.052
3.932AspGlu: 3.932 ± 0.057
2.928AspPhe: 2.928 ± 0.046
4.329AspGly: 4.329 ± 0.073
0.797AspHis: 0.797 ± 0.025
4.13AspIle: 4.13 ± 0.063
4.221AspLys: 4.221 ± 0.055
4.632AspLeu: 4.632 ± 0.064
1.611AspMet: 1.611 ± 0.036
2.905AspAsn: 2.905 ± 0.055
1.938AspPro: 1.938 ± 0.041
1.237AspGln: 1.237 ± 0.033
2.376AspArg: 2.376 ± 0.046
3.014AspSer: 3.014 ± 0.053
2.798AspThr: 2.798 ± 0.053
3.447AspVal: 3.447 ± 0.056
0.933AspTrp: 0.933 ± 0.026
3.015AspTyr: 3.015 ± 0.052
0.0AspXaa: 0.0 ± 0.0
Glu
4.812GluAla: 4.812 ± 0.078
0.622GluCys: 0.622 ± 0.024
3.356GluAsp: 3.356 ± 0.05
5.474GluGlu: 5.474 ± 0.083
2.527GluPhe: 2.527 ± 0.047
4.263GluGly: 4.263 ± 0.059
1.216GluHis: 1.216 ± 0.031
4.671GluIle: 4.671 ± 0.051
5.378GluLys: 5.378 ± 0.079
6.252GluLeu: 6.252 ± 0.078
2.06GluMet: 2.06 ± 0.037
3.654GluAsn: 3.654 ± 0.052
1.834GluPro: 1.834 ± 0.036
2.717GluGln: 2.717 ± 0.053
3.264GluArg: 3.264 ± 0.046
3.268GluSer: 3.268 ± 0.049
3.362GluThr: 3.362 ± 0.052
4.342GluVal: 4.342 ± 0.059
0.938GluTrp: 0.938 ± 0.026
2.892GluTyr: 2.892 ± 0.045
0.0GluXaa: 0.0 ± 0.0
Phe
3.012PheAla: 3.012 ± 0.052
0.638PheCys: 0.638 ± 0.019
2.716PheAsp: 2.716 ± 0.039
2.496PheGlu: 2.496 ± 0.046
2.168PhePhe: 2.168 ± 0.049
3.197PheGly: 3.197 ± 0.055
0.866PheHis: 0.866 ± 0.027
3.233PheIle: 3.233 ± 0.053
2.427PheLys: 2.427 ± 0.042
3.97PheLeu: 3.97 ± 0.062
1.211PheMet: 1.211 ± 0.03
2.466PheAsn: 2.466 ± 0.046
1.792PhePro: 1.792 ± 0.036
1.341PheGln: 1.341 ± 0.032
2.083PheArg: 2.083 ± 0.043
3.445PheSer: 3.445 ± 0.057
2.831PheThr: 2.831 ± 0.045
2.813PheVal: 2.813 ± 0.052
0.576PheTrp: 0.576 ± 0.022
2.063PheTyr: 2.063 ± 0.04
0.0PheXaa: 0.0 ± 0.0
Gly
4.431GlyAla: 4.431 ± 0.071
0.884GlyCys: 0.884 ± 0.027
3.569GlyAsp: 3.569 ± 0.059
4.401GlyGlu: 4.401 ± 0.061
3.18GlyPhe: 3.18 ± 0.05
4.755GlyGly: 4.755 ± 0.082
1.203GlyHis: 1.203 ± 0.03
5.357GlyIle: 5.357 ± 0.066
5.376GlyLys: 5.376 ± 0.07
5.807GlyLeu: 5.807 ± 0.074
2.124GlyMet: 2.124 ± 0.041
3.705GlyAsn: 3.705 ± 0.052
1.3GlyPro: 1.3 ± 0.036
2.046GlyGln: 2.046 ± 0.036
2.824GlyArg: 2.824 ± 0.05
3.937GlySer: 3.937 ± 0.066
4.248GlyThr: 4.248 ± 0.071
4.764GlyVal: 4.764 ± 0.064
1.064GlyTrp: 1.064 ± 0.024
3.557GlyTyr: 3.557 ± 0.063
0.0GlyXaa: 0.0 ± 0.0
His
1.047HisAla: 1.047 ± 0.033
0.302HisCys: 0.302 ± 0.016
0.871HisAsp: 0.871 ± 0.027
0.987HisGlu: 0.987 ± 0.029
0.989HisPhe: 0.989 ± 0.028
1.168HisGly: 1.168 ± 0.028
0.438HisHis: 0.438 ± 0.019
1.391HisIle: 1.391 ± 0.033
1.017HisLys: 1.017 ± 0.029
1.71HisLeu: 1.71 ± 0.04
0.344HisMet: 0.344 ± 0.014
0.922HisAsn: 0.922 ± 0.026
1.044HisPro: 1.044 ± 0.03
0.605HisGln: 0.605 ± 0.024
0.844HisArg: 0.844 ± 0.026
1.139HisSer: 1.139 ± 0.029
1.052HisThr: 1.052 ± 0.029
0.92HisVal: 0.92 ± 0.026
0.281HisTrp: 0.281 ± 0.015
0.909HisTyr: 0.909 ± 0.028
0.0HisXaa: 0.0 ± 0.0
Ile
5.24IleAla: 5.24 ± 0.075
0.939IleCys: 0.939 ± 0.025
4.236IleAsp: 4.236 ± 0.054
4.53IleGlu: 4.53 ± 0.065
2.788IlePhe: 2.788 ± 0.049
4.703IleGly: 4.703 ± 0.065
1.344IleHis: 1.344 ± 0.03
4.612IleIle: 4.612 ± 0.079
4.184IleLys: 4.184 ± 0.058
5.998IleLeu: 5.998 ± 0.082
1.467IleMet: 1.467 ± 0.034
3.561IleAsn: 3.561 ± 0.055
3.245IlePro: 3.245 ± 0.055
2.25IleGln: 2.25 ± 0.042
3.428IleArg: 3.428 ± 0.051
4.715IleSer: 4.715 ± 0.059
4.073IleThr: 4.073 ± 0.053
4.233IleVal: 4.233 ± 0.059
0.736IleTrp: 0.736 ± 0.025
2.946IleTyr: 2.946 ± 0.044
0.0IleXaa: 0.0 ± 0.0
Lys
4.902LysAla: 4.902 ± 0.068
0.531LysCys: 0.531 ± 0.022
4.183LysAsp: 4.183 ± 0.063
6.1LysGlu: 6.1 ± 0.077
2.267LysPhe: 2.267 ± 0.043
4.739LysGly: 4.739 ± 0.068
1.177LysHis: 1.177 ± 0.03
4.265LysIle: 4.265 ± 0.06
5.448LysLys: 5.448 ± 0.071
5.425LysLeu: 5.425 ± 0.067
2.185LysMet: 2.185 ± 0.047
3.705LysAsn: 3.705 ± 0.057
2.159LysPro: 2.159 ± 0.039
2.566LysGln: 2.566 ± 0.041
3.109LysArg: 3.109 ± 0.046
3.341LysSer: 3.341 ± 0.051
3.569LysThr: 3.569 ± 0.053
4.471LysVal: 4.471 ± 0.07
0.854LysTrp: 0.854 ± 0.027
3.159LysTyr: 3.159 ± 0.053
0.0LysXaa: 0.0 ± 0.0
Leu
6.115LeuAla: 6.115 ± 0.074
1.289LeuCys: 1.289 ± 0.033
4.516LeuAsp: 4.516 ± 0.059
5.136LeuGlu: 5.136 ± 0.061
4.457LeuPhe: 4.457 ± 0.073
5.534LeuGly: 5.534 ± 0.069
1.642LeuHis: 1.642 ± 0.037
5.555LeuIle: 5.555 ± 0.079
6.46LeuLys: 6.46 ± 0.071
8.738LeuLeu: 8.738 ± 0.111
2.384LeuMet: 2.384 ± 0.048
4.678LeuAsn: 4.678 ± 0.065
4.117LeuPro: 4.117 ± 0.051
3.236LeuGln: 3.236 ± 0.063
4.081LeuArg: 4.081 ± 0.068
6.577LeuSer: 6.577 ± 0.074
5.263LeuThr: 5.263 ± 0.07
5.028LeuVal: 5.028 ± 0.065
1.056LeuTrp: 1.056 ± 0.036
3.709LeuTyr: 3.709 ± 0.06
0.0LeuXaa: 0.0 ± 0.0
Met
1.987MetAla: 1.987 ± 0.045
0.249MetCys: 0.249 ± 0.013
1.484MetAsp: 1.484 ± 0.034
1.851MetGlu: 1.851 ± 0.034
0.995MetPhe: 0.995 ± 0.028
1.832MetGly: 1.832 ± 0.039
0.43MetHis: 0.43 ± 0.019
1.692MetIle: 1.692 ± 0.037
2.7MetLys: 2.7 ± 0.048
2.373MetLeu: 2.373 ± 0.047
0.803MetMet: 0.803 ± 0.029
1.638MetAsn: 1.638 ± 0.034
1.081MetPro: 1.081 ± 0.028
1.016MetGln: 1.016 ± 0.03
1.267MetArg: 1.267 ± 0.037
1.523MetSer: 1.523 ± 0.033
1.542MetThr: 1.542 ± 0.032
1.599MetVal: 1.599 ± 0.035
0.305MetTrp: 0.305 ± 0.016
0.98MetTyr: 0.98 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
3.424AsnAla: 3.424 ± 0.056
0.528AsnCys: 0.528 ± 0.021
2.716AsnAsp: 2.716 ± 0.056
3.268AsnGlu: 3.268 ± 0.049
2.32AsnPhe: 2.32 ± 0.035
4.182AsnGly: 4.182 ± 0.065
0.952AsnHis: 0.952 ± 0.027
3.85AsnIle: 3.85 ± 0.057
3.481AsnLys: 3.481 ± 0.051
4.484AsnLeu: 4.484 ± 0.071
1.334AsnMet: 1.334 ± 0.03
2.855AsnAsn: 2.855 ± 0.061
2.609AsnPro: 2.609 ± 0.047
1.73AsnGln: 1.73 ± 0.038
2.436AsnArg: 2.436 ± 0.048
2.943AsnSer: 2.943 ± 0.048
2.832AsnThr: 2.832 ± 0.047
3.371AsnVal: 3.371 ± 0.052
0.725AsnTrp: 0.725 ± 0.023
2.512AsnTyr: 2.512 ± 0.044
0.0AsnXaa: 0.0 ± 0.0
Pro
2.681ProAla: 2.681 ± 0.056
0.363ProCys: 0.363 ± 0.016
2.502ProAsp: 2.502 ± 0.039
3.477ProGlu: 3.477 ± 0.053
1.859ProPhe: 1.859 ± 0.035
2.494ProGly: 2.494 ± 0.048
0.658ProHis: 0.658 ± 0.022
2.388ProIle: 2.388 ± 0.045
2.045ProLys: 2.045 ± 0.037
3.211ProLeu: 3.211 ± 0.05
0.951ProMet: 0.951 ± 0.031
1.896ProAsn: 1.896 ± 0.04
0.782ProPro: 0.782 ± 0.025
1.454ProGln: 1.454 ± 0.036
1.325ProArg: 1.325 ± 0.032
2.333ProSer: 2.333 ± 0.043
2.012ProThr: 2.012 ± 0.038
3.007ProVal: 3.007 ± 0.046
0.445ProTrp: 0.445 ± 0.021
1.815ProTyr: 1.815 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
2.424GlnAla: 2.424 ± 0.047
0.306GlnCys: 0.306 ± 0.014
1.551GlnAsp: 1.551 ± 0.036
2.367GlnGlu: 2.367 ± 0.044
1.34GlnPhe: 1.34 ± 0.031
2.055GlnGly: 2.055 ± 0.045
0.619GlnHis: 0.619 ± 0.023
2.373GlnIle: 2.373 ± 0.047
2.549GlnLys: 2.549 ± 0.046
3.273GlnLeu: 3.273 ± 0.06
1.08GlnMet: 1.08 ± 0.028
1.759GlnAsn: 1.759 ± 0.036
1.313GlnPro: 1.313 ± 0.036
1.528GlnGln: 1.528 ± 0.042
1.653GlnArg: 1.653 ± 0.038
1.927GlnSer: 1.927 ± 0.036
2.01GlnThr: 2.01 ± 0.04
2.185GlnVal: 2.185 ± 0.043
0.475GlnTrp: 0.475 ± 0.02
1.496GlnTyr: 1.496 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
2.71ArgAla: 2.71 ± 0.039
0.434ArgCys: 0.434 ± 0.022
2.098ArgAsp: 2.098 ± 0.041
2.922ArgGlu: 2.922 ± 0.054
2.322ArgPhe: 2.322 ± 0.041
2.43ArgGly: 2.43 ± 0.046
0.827ArgHis: 0.827 ± 0.028
3.538ArgIle: 3.538 ± 0.05
3.388ArgLys: 3.388 ± 0.055
4.252ArgLeu: 4.252 ± 0.055
1.502ArgMet: 1.502 ± 0.035
2.476ArgAsn: 2.476 ± 0.043
1.659ArgPro: 1.659 ± 0.038
1.745ArgGln: 1.745 ± 0.037
2.171ArgArg: 2.171 ± 0.038
2.473ArgSer: 2.473 ± 0.049
2.484ArgThr: 2.484 ± 0.04
2.613ArgVal: 2.613 ± 0.046
0.667ArgTrp: 0.667 ± 0.024
2.198ArgTyr: 2.198 ± 0.049
0.0ArgXaa: 0.0 ± 0.0
Ser
4.163SerAla: 4.163 ± 0.057
0.848SerCys: 0.848 ± 0.028
3.425SerAsp: 3.425 ± 0.046
3.57SerGlu: 3.57 ± 0.055
3.217SerPhe: 3.217 ± 0.055
4.462SerGly: 4.462 ± 0.066
1.102SerHis: 1.102 ± 0.031
4.451SerIle: 4.451 ± 0.061
3.521SerLys: 3.521 ± 0.047
5.893SerLeu: 5.893 ± 0.072
1.532SerMet: 1.532 ± 0.034
2.87SerAsn: 2.87 ± 0.056
2.331SerPro: 2.331 ± 0.039
1.933SerGln: 1.933 ± 0.041
2.563SerArg: 2.563 ± 0.046
4.083SerSer: 4.083 ± 0.068
3.312SerThr: 3.312 ± 0.054
4.239SerVal: 4.239 ± 0.055
0.884SerTrp: 0.884 ± 0.025
2.925SerTyr: 2.925 ± 0.053
0.0SerXaa: 0.0 ± 0.0
Thr
3.947ThrAla: 3.947 ± 0.054
0.574ThrCys: 0.574 ± 0.023
3.495ThrAsp: 3.495 ± 0.055
3.485ThrGlu: 3.485 ± 0.054
2.86ThrPhe: 2.86 ± 0.053
4.435ThrGly: 4.435 ± 0.061
1.007ThrHis: 1.007 ± 0.025
3.839ThrIle: 3.839 ± 0.057
2.982ThrLys: 2.982 ± 0.047
5.351ThrLeu: 5.351 ± 0.066
1.245ThrMet: 1.245 ± 0.029
2.616ThrAsn: 2.616 ± 0.046
2.845ThrPro: 2.845 ± 0.05
1.768ThrGln: 1.768 ± 0.034
2.211ThrArg: 2.211 ± 0.041
3.439ThrSer: 3.439 ± 0.063
3.159ThrThr: 3.159 ± 0.048
4.088ThrVal: 4.088 ± 0.064
0.722ThrTrp: 0.722 ± 0.024
2.561ThrTyr: 2.561 ± 0.047
0.0ThrXaa: 0.0 ± 0.0
Val
4.477ValAla: 4.477 ± 0.066
0.964ValCys: 0.964 ± 0.028
3.722ValAsp: 3.722 ± 0.059
4.077ValGlu: 4.077 ± 0.063
2.762ValPhe: 2.762 ± 0.042
4.121ValGly: 4.121 ± 0.064
1.089ValHis: 1.089 ± 0.034
4.387ValIle: 4.387 ± 0.059
4.28ValLys: 4.28 ± 0.063
5.553ValLeu: 5.553 ± 0.07
1.66ValMet: 1.66 ± 0.035
3.404ValAsn: 3.404 ± 0.049
2.539ValPro: 2.539 ± 0.049
1.926ValGln: 1.926 ± 0.042
2.886ValArg: 2.886 ± 0.044
4.519ValSer: 4.519 ± 0.063
3.883ValThr: 3.883 ± 0.058
4.275ValVal: 4.275 ± 0.066
0.764ValTrp: 0.764 ± 0.024
2.649ValTyr: 2.649 ± 0.046
0.0ValXaa: 0.0 ± 0.0
Trp
0.823TrpAla: 0.823 ± 0.028
0.178TrpCys: 0.178 ± 0.012
0.768TrpAsp: 0.768 ± 0.025
0.901TrpGlu: 0.901 ± 0.027
0.561TrpPhe: 0.561 ± 0.021
1.02TrpGly: 1.02 ± 0.028
0.255TrpHis: 0.255 ± 0.012
0.857TrpIle: 0.857 ± 0.028
1.012TrpLys: 1.012 ± 0.034
1.155TrpLeu: 1.155 ± 0.032
0.496TrpMet: 0.496 ± 0.018
0.905TrpAsn: 0.905 ± 0.025
0.3TrpPro: 0.3 ± 0.015
0.521TrpGln: 0.521 ± 0.017
0.568TrpArg: 0.568 ± 0.022
0.716TrpSer: 0.716 ± 0.023
0.722TrpThr: 0.722 ± 0.024
0.758TrpVal: 0.758 ± 0.026
0.231TrpTrp: 0.231 ± 0.013
0.55TrpTyr: 0.55 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.063TyrAla: 3.063 ± 0.043
0.571TyrCys: 0.571 ± 0.02
2.626TyrAsp: 2.626 ± 0.044
2.59TyrGlu: 2.59 ± 0.046
2.148TyrPhe: 2.148 ± 0.042
2.99TyrGly: 2.99 ± 0.048
0.894TyrHis: 0.894 ± 0.028
2.953TyrIle: 2.953 ± 0.044
2.822TyrLys: 2.822 ± 0.051
4.004TyrLeu: 4.004 ± 0.049
1.115TyrMet: 1.115 ± 0.028
2.665TyrAsn: 2.665 ± 0.048
2.037TyrPro: 2.037 ± 0.043
1.682TyrGln: 1.682 ± 0.038
2.325TyrArg: 2.325 ± 0.047
2.92TyrSer: 2.92 ± 0.053
2.833TyrThr: 2.833 ± 0.049
2.537TyrVal: 2.537 ± 0.043
0.657TyrTrp: 0.657 ± 0.02
2.247TyrTyr: 2.247 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3498 proteins (1331831 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski