Amino acid dipepetide frequency for Zhejiang mosquito virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.328AlaAla: 12.328 ± 3.597
3.319AlaCys: 3.319 ± 1.801
5.216AlaAsp: 5.216 ± 1.799
5.69AlaGlu: 5.69 ± 1.438
2.845AlaPhe: 2.845 ± 1.44
9.957AlaGly: 9.957 ± 0.353
3.793AlaHis: 3.793 ± 0.003
5.216AlaIle: 5.216 ± 1.799
2.371AlaLys: 2.371 ± 0.362
8.061AlaLeu: 8.061 ± 1.797
1.897AlaMet: 1.897 ± 1.441
2.845AlaAsn: 2.845 ± 0.719
3.793AlaPro: 3.793 ± 0.718
4.267AlaGln: 4.267 ± 2.521
11.38AlaArg: 11.38 ± 2.877
5.69AlaSer: 5.69 ± 1.438
6.164AlaThr: 6.164 ± 3.241
7.587AlaVal: 7.587 ± 0.005
2.845AlaTrp: 2.845 ± 1.44
0.474AlaTyr: 0.474 ± 0.361
0.0AlaXaa: 0.0 ± 0.0
Cys
0.948CysAla: 0.948 ± 0.001
0.474CysCys: 0.474 ± 0.361
0.948CysAsp: 0.948 ± 0.721
0.948CysGlu: 0.948 ± 0.001
0.474CysPhe: 0.474 ± 0.361
0.948CysGly: 0.948 ± 0.722
0.0CysHis: 0.0 ± 0.0
0.474CysIle: 0.474 ± 0.361
0.0CysLys: 0.0 ± 0.0
2.371CysLeu: 2.371 ± 0.362
0.474CysMet: 0.474 ± 0.36
0.0CysAsn: 0.0 ± 0.0
2.845CysPro: 2.845 ± 0.723
0.474CysGln: 0.474 ± 0.361
4.267CysArg: 4.267 ± 1.806
2.845CysSer: 2.845 ± 1.444
0.474CysThr: 0.474 ± 0.36
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.742AspAla: 4.742 ± 2.16
1.422AspCys: 1.422 ± 0.362
0.948AspAsp: 0.948 ± 0.721
0.474AspGlu: 0.474 ± 0.361
0.948AspPhe: 0.948 ± 0.722
3.793AspGly: 3.793 ± 0.724
0.474AspHis: 0.474 ± 0.361
1.422AspIle: 1.422 ± 1.083
0.948AspLys: 0.948 ± 0.722
8.061AspLeu: 8.061 ± 1.076
0.0AspMet: 0.0 ± 0.0
0.948AspAsn: 0.948 ± 0.721
2.845AspPro: 2.845 ± 0.719
2.371AspGln: 2.371 ± 0.362
4.742AspArg: 4.742 ± 1.446
1.897AspSer: 1.897 ± 0.723
1.422AspThr: 1.422 ± 0.36
2.371AspVal: 2.371 ± 0.359
0.0AspTrp: 0.0 ± 0.0
0.474AspTyr: 0.474 ± 0.36
0.0AspXaa: 0.0 ± 0.0
Glu
5.216GluAla: 5.216 ± 0.357
0.474GluCys: 0.474 ± 0.36
1.897GluAsp: 1.897 ± 0.72
1.422GluGlu: 1.422 ± 0.36
1.897GluPhe: 1.897 ± 0.001
7.112GluGly: 7.112 ± 1.087
1.422GluHis: 1.422 ± 0.36
0.948GluIle: 0.948 ± 0.721
0.948GluLys: 0.948 ± 0.001
8.061GluLeu: 8.061 ± 0.355
0.0GluMet: 0.0 ± 0.0
0.474GluAsn: 0.474 ± 0.361
3.793GluPro: 3.793 ± 0.718
1.422GluGln: 1.422 ± 1.083
6.638GluArg: 6.638 ± 0.005
3.793GluSer: 3.793 ± 1.445
2.371GluThr: 2.371 ± 0.362
5.69GluVal: 5.69 ± 0.004
0.948GluTrp: 0.948 ± 0.001
0.474GluTyr: 0.474 ± 0.36
0.0GluXaa: 0.0 ± 0.0
Phe
1.422PheAla: 1.422 ± 0.362
0.948PheCys: 0.948 ± 0.722
2.845PheAsp: 2.845 ± 1.44
3.319PheGlu: 3.319 ± 1.079
0.474PhePhe: 0.474 ± 0.36
2.845PheGly: 2.845 ± 2.166
0.474PheHis: 0.474 ± 0.36
0.0PheIle: 0.0 ± 0.0
0.0PheLys: 0.0 ± 0.0
1.422PheLeu: 1.422 ± 0.36
0.0PheMet: 0.0 ± 0.0
0.948PheAsn: 0.948 ± 0.001
3.793PhePro: 3.793 ± 0.724
0.0PheGln: 0.0 ± 0.0
3.319PheArg: 3.319 ± 1.084
0.948PheSer: 0.948 ± 0.001
0.474PheThr: 0.474 ± 0.36
0.948PheVal: 0.948 ± 0.001
0.474PheTrp: 0.474 ± 0.361
0.948PheTyr: 0.948 ± 0.721
0.0PheXaa: 0.0 ± 0.0
Gly
9.483GlyAla: 9.483 ± 1.436
1.897GlyCys: 1.897 ± 0.723
6.164GlyAsp: 6.164 ± 0.356
5.69GlyGlu: 5.69 ± 1.438
3.319GlyPhe: 3.319 ± 1.079
9.483GlyGly: 9.483 ± 0.007
4.742GlyHis: 4.742 ± 2.888
1.897GlyIle: 1.897 ± 1.444
1.897GlyLys: 1.897 ± 0.001
9.957GlyLeu: 9.957 ± 1.796
0.948GlyMet: 0.948 ± 0.721
1.422GlyAsn: 1.422 ± 0.362
4.267GlyPro: 4.267 ± 1.085
6.164GlyGln: 6.164 ± 2.529
9.009GlyArg: 9.009 ± 3.252
3.319GlySer: 3.319 ± 0.363
5.69GlyThr: 5.69 ± 2.168
9.009GlyVal: 9.009 ± 2.531
0.948GlyTrp: 0.948 ± 0.721
1.422GlyTyr: 1.422 ± 0.36
0.0GlyXaa: 0.0 ± 0.0
His
1.422HisAla: 1.422 ± 0.36
1.422HisCys: 1.422 ± 1.083
2.371HisAsp: 2.371 ± 1.084
1.422HisGlu: 1.422 ± 0.362
0.948HisPhe: 0.948 ± 0.001
1.897HisGly: 1.897 ± 0.723
0.948HisHis: 0.948 ± 0.722
0.474HisIle: 0.474 ± 0.36
0.474HisLys: 0.474 ± 0.36
1.422HisLeu: 1.422 ± 0.362
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.897HisPro: 1.897 ± 0.72
0.474HisGln: 0.474 ± 0.361
5.69HisArg: 5.69 ± 2.168
3.793HisSer: 3.793 ± 1.445
1.897HisThr: 1.897 ± 0.001
0.948HisVal: 0.948 ± 0.722
0.948HisTrp: 0.948 ± 0.722
0.948HisTyr: 0.948 ± 0.001
0.0HisXaa: 0.0 ± 0.0
Ile
2.845IleAla: 2.845 ± 0.719
0.0IleCys: 0.0 ± 0.0
1.422IleAsp: 1.422 ± 0.36
2.845IleGlu: 2.845 ± 1.444
0.0IlePhe: 0.0 ± 0.0
1.422IleGly: 1.422 ± 1.081
0.474IleHis: 0.474 ± 0.36
0.474IleIle: 0.474 ± 0.361
0.474IleLys: 0.474 ± 0.36
0.474IleLeu: 0.474 ± 0.36
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
3.319IlePro: 3.319 ± 1.801
0.474IleGln: 0.474 ± 0.36
4.267IleArg: 4.267 ± 0.358
1.422IleSer: 1.422 ± 0.362
0.0IleThr: 0.0 ± 0.0
1.422IleVal: 1.422 ± 0.362
1.422IleTrp: 1.422 ± 0.36
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
6.164LysAla: 6.164 ± 1.077
0.0LysCys: 0.0 ± 0.0
0.474LysAsp: 0.474 ± 0.361
2.845LysGlu: 2.845 ± 0.002
0.474LysPhe: 0.474 ± 0.361
3.319LysGly: 3.319 ± 0.358
0.948LysHis: 0.948 ± 0.001
0.0LysIle: 0.0 ± 0.0
0.474LysLys: 0.474 ± 0.36
3.319LysLeu: 3.319 ± 0.358
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
1.422LysPro: 1.422 ± 0.36
1.897LysGln: 1.897 ± 0.72
2.371LysArg: 2.371 ± 1.801
2.371LysSer: 2.371 ± 0.362
2.845LysThr: 2.845 ± 0.002
1.897LysVal: 1.897 ± 0.001
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.061LeuAla: 8.061 ± 3.24
1.422LeuCys: 1.422 ± 0.362
3.319LeuAsp: 3.319 ± 1.084
4.267LeuGlu: 4.267 ± 1.085
0.948LeuPhe: 0.948 ± 0.001
13.276LeuGly: 13.276 ± 0.01
2.371LeuHis: 2.371 ± 0.362
1.897LeuIle: 1.897 ± 0.72
4.742LeuLys: 4.742 ± 0.718
13.276LeuLeu: 13.276 ± 4.337
0.948LeuMet: 0.948 ± 0.721
1.897LeuAsn: 1.897 ± 0.723
8.535LeuPro: 8.535 ± 0.006
3.793LeuGln: 3.793 ± 0.724
9.483LeuArg: 9.483 ± 0.007
7.587LeuSer: 7.587 ± 0.716
5.69LeuThr: 5.69 ± 0.004
4.742LeuVal: 4.742 ± 1.439
0.948LeuTrp: 0.948 ± 0.721
2.371LeuTyr: 2.371 ± 1.801
0.0LeuXaa: 0.0 ± 0.0
Met
0.948MetAla: 0.948 ± 0.721
0.0MetCys: 0.0 ± 0.0
0.474MetAsp: 0.474 ± 0.36
0.0MetGlu: 0.0 ± 0.0
0.474MetPhe: 0.474 ± 0.361
1.897MetGly: 1.897 ± 0.001
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.474MetLys: 0.474 ± 0.36
0.474MetLeu: 0.474 ± 0.36
0.474MetMet: 0.474 ± 0.36
0.0MetAsn: 0.0 ± 0.0
1.422MetPro: 1.422 ± 0.36
0.474MetGln: 0.474 ± 0.36
0.0MetArg: 0.0 ± 0.0
0.948MetSer: 0.948 ± 0.721
0.948MetThr: 0.948 ± 0.721
0.0MetVal: 0.0 ± 0.0
0.474MetTrp: 0.474 ± 0.36
0.474MetTyr: 0.474 ± 0.36
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.948AsnAsp: 0.948 ± 0.722
0.948AsnGlu: 0.948 ± 0.722
0.474AsnPhe: 0.474 ± 0.361
2.845AsnGly: 2.845 ± 1.444
0.474AsnHis: 0.474 ± 0.36
0.0AsnIle: 0.0 ± 0.0
0.474AsnLys: 0.474 ± 0.361
1.897AsnLeu: 1.897 ± 0.72
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.422AsnPro: 1.422 ± 0.36
0.0AsnGln: 0.0 ± 0.0
4.742AsnArg: 4.742 ± 0.725
2.371AsnSer: 2.371 ± 0.362
0.474AsnThr: 0.474 ± 0.36
2.371AsnVal: 2.371 ± 0.359
0.0AsnTrp: 0.0 ± 0.0
0.474AsnTyr: 0.474 ± 0.36
0.0AsnXaa: 0.0 ± 0.0
Pro
8.061ProAla: 8.061 ± 2.518
0.474ProCys: 0.474 ± 0.361
3.319ProAsp: 3.319 ± 0.363
3.319ProGlu: 3.319 ± 0.363
3.793ProPhe: 3.793 ± 1.445
5.69ProGly: 5.69 ± 2.168
0.948ProHis: 0.948 ± 0.001
1.897ProIle: 1.897 ± 1.441
3.319ProLys: 3.319 ± 1.801
5.216ProLeu: 5.216 ± 0.364
1.897ProMet: 1.897 ± 0.72
1.897ProAsn: 1.897 ± 0.001
5.216ProPro: 5.216 ± 2.52
2.371ProGln: 2.371 ± 1.084
9.957ProArg: 9.957 ± 0.368
4.267ProSer: 4.267 ± 0.364
3.793ProThr: 3.793 ± 1.445
5.216ProVal: 5.216 ± 1.799
1.422ProTrp: 1.422 ± 0.362
0.474ProTyr: 0.474 ± 0.36
0.0ProXaa: 0.0 ± 0.0
Gln
3.793GlnAla: 3.793 ± 0.724
0.948GlnCys: 0.948 ± 0.001
0.474GlnAsp: 0.474 ± 0.361
2.845GlnGlu: 2.845 ± 1.44
1.422GlnPhe: 1.422 ± 0.36
2.371GlnGly: 2.371 ± 0.362
2.371GlnHis: 2.371 ± 1.084
0.948GlnIle: 0.948 ± 0.721
1.897GlnLys: 1.897 ± 1.441
4.742GlnLeu: 4.742 ± 0.725
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.897GlnPro: 1.897 ± 0.001
2.371GlnGln: 2.371 ± 0.359
3.793GlnArg: 3.793 ± 1.445
2.371GlnSer: 2.371 ± 1.805
0.948GlnThr: 0.948 ± 0.001
5.216GlnVal: 5.216 ± 1.807
0.0GlnTrp: 0.0 ± 0.0
0.948GlnTyr: 0.948 ± 0.722
0.0GlnXaa: 0.0 ± 0.0
Arg
11.38ArgAla: 11.38 ± 2.155
1.897ArgCys: 1.897 ± 1.444
2.845ArgAsp: 2.845 ± 2.166
4.267ArgGlu: 4.267 ± 0.358
1.897ArgPhe: 1.897 ± 0.001
11.38ArgGly: 11.38 ± 0.713
5.216ArgHis: 5.216 ± 2.528
0.948ArgIle: 0.948 ± 0.001
6.638ArgLys: 6.638 ± 0.005
12.328ArgLeu: 12.328 ± 0.009
2.371ArgMet: 2.371 ± 0.002
4.267ArgAsn: 4.267 ± 2.527
7.587ArgPro: 7.587 ± 2.89
3.319ArgGln: 3.319 ± 1.084
15.647ArgArg: 15.647 ± 2.535
9.483ArgSer: 9.483 ± 0.007
7.112ArgThr: 7.112 ± 0.355
7.112ArgVal: 7.112 ± 1.808
0.474ArgTrp: 0.474 ± 0.361
1.897ArgTyr: 1.897 ± 0.723
0.0ArgXaa: 0.0 ± 0.0
Ser
9.483SerAla: 9.483 ± 2.878
1.422SerCys: 1.422 ± 0.362
2.371SerAsp: 2.371 ± 1.084
4.267SerGlu: 4.267 ± 0.364
1.422SerPhe: 1.422 ± 0.362
4.742SerGly: 4.742 ± 0.718
1.897SerHis: 1.897 ± 0.723
0.474SerIle: 0.474 ± 0.36
1.422SerLys: 1.422 ± 0.362
7.587SerLeu: 7.587 ± 0.005
0.0SerMet: 0.0 ± 0.0
0.474SerAsn: 0.474 ± 0.361
5.216SerPro: 5.216 ± 1.086
2.371SerGln: 2.371 ± 0.362
7.112SerArg: 7.112 ± 1.808
2.845SerSer: 2.845 ± 0.723
4.267SerThr: 4.267 ± 1.806
4.742SerVal: 4.742 ± 0.718
0.948SerTrp: 0.948 ± 0.001
2.371SerTyr: 2.371 ± 1.084
0.0SerXaa: 0.0 ± 0.0
Thr
5.69ThrAla: 5.69 ± 2.159
0.474ThrCys: 0.474 ± 0.361
1.422ThrAsp: 1.422 ± 0.36
1.897ThrGlu: 1.897 ± 0.72
1.422ThrPhe: 1.422 ± 1.081
4.742ThrGly: 4.742 ± 1.446
0.948ThrHis: 0.948 ± 0.001
2.845ThrIle: 2.845 ± 0.002
2.845ThrLys: 2.845 ± 0.719
3.319ThrLeu: 3.319 ± 1.084
0.0ThrMet: 0.0 ± 0.0
2.371ThrAsn: 2.371 ± 0.359
3.793ThrPro: 3.793 ± 0.724
3.793ThrGln: 3.793 ± 0.724
5.69ThrArg: 5.69 ± 0.004
1.897ThrSer: 1.897 ± 0.723
3.319ThrThr: 3.319 ± 0.358
4.742ThrVal: 4.742 ± 2.16
0.474ThrTrp: 0.474 ± 0.361
0.474ThrTyr: 0.474 ± 0.36
0.0ThrXaa: 0.0 ± 0.0
Val
10.431ValAla: 10.431 ± 4.32
1.422ValCys: 1.422 ± 1.083
1.897ValAsp: 1.897 ± 0.723
7.112ValGlu: 7.112 ± 2.529
2.371ValPhe: 2.371 ± 1.084
6.638ValGly: 6.638 ± 0.726
1.897ValHis: 1.897 ± 0.723
1.422ValIle: 1.422 ± 0.36
0.948ValLys: 0.948 ± 0.001
5.69ValLeu: 5.69 ± 2.159
0.474ValMet: 0.474 ± 0.36
0.948ValAsn: 0.948 ± 0.001
6.638ValPro: 6.638 ± 0.716
2.371ValGln: 2.371 ± 0.359
7.587ValArg: 7.587 ± 2.89
5.69ValSer: 5.69 ± 0.717
1.897ValThr: 1.897 ± 1.441
4.742ValVal: 4.742 ± 0.725
0.474ValTrp: 0.474 ± 0.36
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.371TrpAla: 2.371 ± 0.359
0.0TrpCys: 0.0 ± 0.0
0.948TrpAsp: 0.948 ± 0.721
0.948TrpGlu: 0.948 ± 0.001
0.0TrpPhe: 0.0 ± 0.0
0.474TrpGly: 0.474 ± 0.361
0.0TrpHis: 0.0 ± 0.0
0.474TrpIle: 0.474 ± 0.36
0.0TrpLys: 0.0 ± 0.0
0.948TrpLeu: 0.948 ± 0.722
0.0TrpMet: 0.0 ± 0.0
0.948TrpAsn: 0.948 ± 0.001
0.474TrpPro: 0.474 ± 0.36
0.948TrpGln: 0.948 ± 0.722
0.948TrpArg: 0.948 ± 0.001
0.948TrpSer: 0.948 ± 0.721
1.897TrpThr: 1.897 ± 0.72
0.474TrpVal: 0.474 ± 0.36
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.948TyrAla: 0.948 ± 0.721
0.948TyrCys: 0.948 ± 0.001
0.0TyrAsp: 0.0 ± 0.0
0.474TyrGlu: 0.474 ± 0.36
0.0TyrPhe: 0.0 ± 0.0
1.897TyrGly: 1.897 ± 0.723
0.0TyrHis: 0.0 ± 0.0
0.948TyrIle: 0.948 ± 0.001
0.474TyrLys: 0.474 ± 0.361
0.948TyrLeu: 0.948 ± 0.001
0.0TyrMet: 0.0 ± 0.0
0.474TyrAsn: 0.474 ± 0.36
2.371TyrPro: 2.371 ± 0.359
0.0TyrGln: 0.0 ± 0.0
1.897TyrArg: 1.897 ± 0.001
0.948TyrSer: 0.948 ± 0.001
0.474TyrThr: 0.474 ± 0.36
1.422TyrVal: 1.422 ± 1.081
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2110 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski