Amino acid dipepetide frequency for Hubei coleoptera virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.077AlaAla: 2.077 ± 0.945
0.462AlaCys: 0.462 ± 0.267
2.077AlaAsp: 2.077 ± 0.206
2.769AlaGlu: 2.769 ± 0.617
2.769AlaPhe: 2.769 ± 0.86
1.846AlaGly: 1.846 ± 0.704
1.154AlaHis: 1.154 ± 0.123
2.308AlaIle: 2.308 ± 1.274
2.769AlaLys: 2.769 ± 0.719
5.077AlaLeu: 5.077 ± 0.524
2.077AlaMet: 2.077 ± 0.739
2.769AlaAsn: 2.769 ± 0.559
1.846AlaPro: 1.846 ± 1.137
2.077AlaGln: 2.077 ± 0.517
2.539AlaArg: 2.539 ± 0.808
4.616AlaSer: 4.616 ± 0.147
4.616AlaThr: 4.616 ± 0.963
2.077AlaVal: 2.077 ± 0.675
0.0AlaTrp: 0.0 ± 0.0
1.385AlaTyr: 1.385 ± 0.579
0.0AlaXaa: 0.0 ± 0.0
Cys
0.462CysAla: 0.462 ± 0.543
0.462CysCys: 0.462 ± 0.267
1.154CysAsp: 1.154 ± 0.263
0.692CysGlu: 0.692 ± 0.225
0.462CysPhe: 0.462 ± 0.145
0.231CysGly: 0.231 ± 0.133
0.692CysHis: 0.692 ± 0.149
0.0CysIle: 0.0 ± 0.0
0.692CysLys: 0.692 ± 0.708
2.308CysLeu: 2.308 ± 0.56
0.231CysMet: 0.231 ± 0.133
0.692CysAsn: 0.692 ± 0.4
0.692CysPro: 0.692 ± 0.708
0.923CysGln: 0.923 ± 0.243
0.923CysArg: 0.923 ± 0.291
1.385CysSer: 1.385 ± 0.489
1.154CysThr: 1.154 ± 0.263
0.231CysVal: 0.231 ± 0.236
0.231CysTrp: 0.231 ± 0.236
0.923CysTyr: 0.923 ± 0.243
0.0CysXaa: 0.0 ± 0.0
Asp
2.539AspAla: 2.539 ± 0.686
0.692AspCys: 0.692 ± 0.4
2.539AspAsp: 2.539 ± 0.808
2.539AspGlu: 2.539 ± 0.956
3.231AspPhe: 3.231 ± 0.698
2.769AspGly: 2.769 ± 0.672
1.154AspHis: 1.154 ± 0.123
5.77AspIle: 5.77 ± 0.615
3.693AspLys: 3.693 ± 0.618
6.693AspLeu: 6.693 ± 0.492
1.154AspMet: 1.154 ± 0.263
3.693AspAsn: 3.693 ± 0.281
3.231AspPro: 3.231 ± 0.629
3.0AspGln: 3.0 ± 0.492
1.616AspArg: 1.616 ± 0.619
3.231AspSer: 3.231 ± 0.908
3.231AspThr: 3.231 ± 0.594
2.769AspVal: 2.769 ± 0.828
1.154AspTrp: 1.154 ± 0.123
1.846AspTyr: 1.846 ± 0.478
0.0AspXaa: 0.0 ± 0.0
Glu
1.846GluAla: 1.846 ± 0.39
0.462GluCys: 0.462 ± 0.234
1.616GluAsp: 1.616 ± 0.349
2.539GluGlu: 2.539 ± 0.685
2.077GluPhe: 2.077 ± 0.602
2.077GluGly: 2.077 ± 0.472
1.154GluHis: 1.154 ± 0.362
4.154GluIle: 4.154 ± 1.149
3.0GluLys: 3.0 ± 0.805
6.924GluLeu: 6.924 ± 0.493
1.385GluMet: 1.385 ± 0.132
3.923GluAsn: 3.923 ± 0.548
1.385GluPro: 1.385 ± 0.345
1.616GluGln: 1.616 ± 0.601
2.769GluArg: 2.769 ± 0.733
3.0GluSer: 3.0 ± 0.662
3.231GluThr: 3.231 ± 0.372
3.923GluVal: 3.923 ± 0.734
1.385GluTrp: 1.385 ± 0.298
1.846GluTyr: 1.846 ± 0.14
0.0GluXaa: 0.0 ± 0.0
Phe
1.846PheAla: 1.846 ± 0.598
0.462PheCys: 0.462 ± 0.349
2.308PheAsp: 2.308 ± 0.573
2.769PheGlu: 2.769 ± 1.278
1.846PhePhe: 1.846 ± 0.485
1.616PheGly: 1.616 ± 0.969
1.385PheHis: 1.385 ± 0.298
3.923PheIle: 3.923 ± 1.021
1.846PheLys: 1.846 ± 0.582
4.385PheLeu: 4.385 ± 1.35
1.154PheMet: 1.154 ± 0.263
3.0PheAsn: 3.0 ± 0.325
1.846PhePro: 1.846 ± 0.249
1.385PheGln: 1.385 ± 0.489
3.0PheArg: 3.0 ± 0.927
3.462PheSer: 3.462 ± 0.689
0.923PheThr: 0.923 ± 0.534
3.0PheVal: 3.0 ± 0.675
0.462PheTrp: 0.462 ± 0.267
1.385PheTyr: 1.385 ± 0.132
0.0PheXaa: 0.0 ± 0.0
Gly
2.308GlyAla: 2.308 ± 0.81
0.231GlyCys: 0.231 ± 0.133
2.308GlyAsp: 2.308 ± 1.013
0.692GlyGlu: 0.692 ± 0.149
2.077GlyPhe: 2.077 ± 0.17
2.769GlyGly: 2.769 ± 1.351
1.154GlyHis: 1.154 ± 0.46
3.0GlyIle: 3.0 ± 0.492
3.693GlyLys: 3.693 ± 0.178
4.385GlyLeu: 4.385 ± 1.35
1.154GlyMet: 1.154 ± 0.659
2.077GlyAsn: 2.077 ± 0.485
2.077GlyPro: 2.077 ± 1.147
2.308GlyGln: 2.308 ± 0.816
3.462GlyArg: 3.462 ± 0.85
3.231GlySer: 3.231 ± 0.724
3.231GlyThr: 3.231 ± 0.674
2.539GlyVal: 2.539 ± 0.396
0.923GlyTrp: 0.923 ± 0.534
0.692GlyTyr: 0.692 ± 0.4
0.0GlyXaa: 0.0 ± 0.0
His
1.154HisAla: 1.154 ± 0.362
0.231HisCys: 0.231 ± 0.236
1.846HisAsp: 1.846 ± 0.796
0.462HisGlu: 0.462 ± 0.267
2.077HisPhe: 2.077 ± 0.602
1.385HisGly: 1.385 ± 0.84
0.462HisHis: 0.462 ± 0.145
2.769HisIle: 2.769 ± 0.978
1.154HisLys: 1.154 ± 0.667
4.616HisLeu: 4.616 ± 1.118
0.923HisMet: 0.923 ± 0.534
2.077HisAsn: 2.077 ± 0.794
1.385HisPro: 1.385 ± 0.489
1.154HisGln: 1.154 ± 0.123
0.231HisArg: 0.231 ± 0.133
0.923HisSer: 0.923 ± 0.123
0.0HisThr: 0.0 ± 0.0
1.385HisVal: 1.385 ± 0.436
0.923HisTrp: 0.923 ± 0.243
1.385HisTyr: 1.385 ± 0.489
0.0HisXaa: 0.0 ± 0.0
Ile
3.693IleAla: 3.693 ± 1.12
2.077IleCys: 2.077 ± 0.602
5.308IleAsp: 5.308 ± 1.362
4.154IleGlu: 4.154 ± 1.153
2.077IlePhe: 2.077 ± 0.272
3.462IleGly: 3.462 ± 0.575
1.616IleHis: 1.616 ± 0.716
3.693IleIle: 3.693 ± 0.659
5.539IleLys: 5.539 ± 0.421
7.847IleLeu: 7.847 ± 0.18
1.154IleMet: 1.154 ± 0.264
4.616IleAsn: 4.616 ± 0.352
4.154IlePro: 4.154 ± 0.676
1.616IleGln: 1.616 ± 0.337
1.846IleArg: 1.846 ± 0.39
6.231IleSer: 6.231 ± 0.508
5.077IleThr: 5.077 ± 0.348
4.385IleVal: 4.385 ± 0.714
1.616IleTrp: 1.616 ± 0.362
1.616IleTyr: 1.616 ± 0.38
0.0IleXaa: 0.0 ± 0.0
Lys
3.0LysAla: 3.0 ± 0.137
0.231LysCys: 0.231 ± 0.236
3.0LysAsp: 3.0 ± 0.218
2.539LysGlu: 2.539 ± 0.396
3.0LysPhe: 3.0 ± 0.501
2.308LysGly: 2.308 ± 0.524
1.385LysHis: 1.385 ± 0.486
5.077LysIle: 5.077 ± 1.109
2.539LysLys: 2.539 ± 0.337
6.231LysLeu: 6.231 ± 1.244
2.077LysMet: 2.077 ± 0.609
2.308LysAsn: 2.308 ± 0.386
1.846LysPro: 1.846 ± 0.577
0.692LysGln: 0.692 ± 0.4
2.769LysArg: 2.769 ± 0.617
6.462LysSer: 6.462 ± 1.096
4.154LysThr: 4.154 ± 1.262
4.154LysVal: 4.154 ± 0.283
1.385LysTrp: 1.385 ± 0.737
1.846LysTyr: 1.846 ± 0.485
0.0LysXaa: 0.0 ± 0.0
Leu
4.385LeuAla: 4.385 ± 0.393
1.846LeuCys: 1.846 ± 0.597
6.924LeuAsp: 6.924 ± 1.378
7.154LeuGlu: 7.154 ± 0.19
3.923LeuPhe: 3.923 ± 1.087
5.077LeuGly: 5.077 ± 1.176
2.539LeuHis: 2.539 ± 0.85
7.616LeuIle: 7.616 ± 1.302
5.077LeuLys: 5.077 ± 0.882
12.001LeuLeu: 12.001 ± 0.472
3.923LeuMet: 3.923 ± 0.734
5.539LeuAsn: 5.539 ± 0.754
5.539LeuPro: 5.539 ± 0.581
3.693LeuGln: 3.693 ± 0.938
6.231LeuArg: 6.231 ± 1.072
10.155LeuSer: 10.155 ± 1.259
7.154LeuThr: 7.154 ± 0.725
6.462LeuVal: 6.462 ± 0.558
2.769LeuTrp: 2.769 ± 0.728
4.385LeuTyr: 4.385 ± 0.548
0.0LeuXaa: 0.0 ± 0.0
Met
1.385MetAla: 1.385 ± 0.84
0.692MetCys: 0.692 ± 0.368
2.308MetAsp: 2.308 ± 0.386
1.616MetGlu: 1.616 ± 0.714
2.539MetPhe: 2.539 ± 0.396
0.923MetGly: 0.923 ± 0.352
0.923MetHis: 0.923 ± 0.534
1.385MetIle: 1.385 ± 0.225
1.846MetLys: 1.846 ± 0.246
3.923MetLeu: 3.923 ± 0.739
0.462MetMet: 0.462 ± 0.145
1.846MetAsn: 1.846 ± 0.14
1.154MetPro: 1.154 ± 0.667
0.692MetGln: 0.692 ± 0.225
2.308MetArg: 2.308 ± 0.246
2.769MetSer: 2.769 ± 0.377
3.0MetThr: 3.0 ± 1.035
1.385MetVal: 1.385 ± 0.132
0.692MetTrp: 0.692 ± 0.4
0.923MetTyr: 0.923 ± 0.243
0.0MetXaa: 0.0 ± 0.0
Asn
3.0AsnAla: 3.0 ± 0.492
1.154AsnCys: 1.154 ± 0.836
2.539AsnAsp: 2.539 ± 0.873
4.154AsnGlu: 4.154 ± 1.472
1.846AsnPhe: 1.846 ± 0.577
1.846AsnGly: 1.846 ± 0.249
1.846AsnHis: 1.846 ± 0.485
3.693AsnIle: 3.693 ± 0.817
2.769AsnLys: 2.769 ± 1.158
6.924AsnLeu: 6.924 ± 0.528
1.616AsnMet: 1.616 ± 0.349
4.154AsnAsn: 4.154 ± 0.283
3.0AsnPro: 3.0 ± 0.843
3.693AsnGln: 3.693 ± 1.194
1.616AsnArg: 1.616 ± 0.349
3.462AsnSer: 3.462 ± 1.125
2.308AsnThr: 2.308 ± 1.419
2.539AsnVal: 2.539 ± 0.956
0.462AsnTrp: 0.462 ± 0.267
2.769AsnTyr: 2.769 ± 0.596
0.0AsnXaa: 0.0 ± 0.0
Pro
3.0ProAla: 3.0 ± 0.675
0.231ProCys: 0.231 ± 0.133
4.154ProAsp: 4.154 ± 0.78
2.308ProGlu: 2.308 ± 0.405
1.385ProPhe: 1.385 ± 0.225
2.077ProGly: 2.077 ± 0.517
0.692ProHis: 0.692 ± 0.149
3.923ProIle: 3.923 ± 0.197
2.077ProLys: 2.077 ± 0.485
4.616ProLeu: 4.616 ± 1.118
2.539ProMet: 2.539 ± 0.441
2.077ProAsn: 2.077 ± 0.485
2.539ProPro: 2.539 ± 0.745
1.385ProGln: 1.385 ± 0.132
0.923ProArg: 0.923 ± 0.352
3.0ProSer: 3.0 ± 0.501
4.616ProThr: 4.616 ± 0.614
1.616ProVal: 1.616 ± 0.362
0.692ProTrp: 0.692 ± 0.268
1.385ProTyr: 1.385 ± 0.489
0.0ProXaa: 0.0 ± 0.0
Gln
2.769GlnAla: 2.769 ± 0.86
0.462GlnCys: 0.462 ± 0.145
1.846GlnAsp: 1.846 ± 0.39
1.154GlnGlu: 1.154 ± 0.572
1.154GlnPhe: 1.154 ± 0.123
1.385GlnGly: 1.385 ± 0.45
1.385GlnHis: 1.385 ± 0.486
3.462GlnIle: 3.462 ± 0.793
1.385GlnLys: 1.385 ± 0.132
4.385GlnLeu: 4.385 ± 0.442
1.154GlnMet: 1.154 ± 0.394
1.616GlnAsn: 1.616 ± 0.397
1.385GlnPro: 1.385 ± 1.159
2.077GlnGln: 2.077 ± 0.947
1.154GlnArg: 1.154 ± 0.46
3.0GlnSer: 3.0 ± 0.727
3.462GlnThr: 3.462 ± 0.22
4.616GlnVal: 4.616 ± 0.214
0.923GlnTrp: 0.923 ± 0.743
1.154GlnTyr: 1.154 ± 0.264
0.0GlnXaa: 0.0 ± 0.0
Arg
1.846ArgAla: 1.846 ± 0.577
0.692ArgCys: 0.692 ± 0.149
3.462ArgAsp: 3.462 ± 0.477
3.231ArgGlu: 3.231 ± 0.317
1.846ArgPhe: 1.846 ± 0.83
1.846ArgGly: 1.846 ± 0.246
1.154ArgHis: 1.154 ± 0.667
3.0ArgIle: 3.0 ± 0.805
2.308ArgLys: 2.308 ± 1.274
4.616ArgLeu: 4.616 ± 0.492
1.846ArgMet: 1.846 ± 0.748
3.231ArgAsn: 3.231 ± 0.964
1.154ArgPro: 1.154 ± 0.46
1.385ArgGln: 1.385 ± 0.666
2.308ArgArg: 2.308 ± 0.246
3.462ArgSer: 3.462 ± 0.759
3.462ArgThr: 3.462 ± 0.689
3.0ArgVal: 3.0 ± 0.325
0.462ArgTrp: 0.462 ± 0.349
1.385ArgTyr: 1.385 ± 0.45
0.0ArgXaa: 0.0 ± 0.0
Ser
2.539SerAla: 2.539 ± 0.098
0.923SerCys: 0.923 ± 0.397
4.154SerAsp: 4.154 ± 1.308
4.616SerGlu: 4.616 ± 0.42
3.462SerPhe: 3.462 ± 1.368
3.462SerGly: 3.462 ± 1.384
2.077SerHis: 2.077 ± 1.201
5.308SerIle: 5.308 ± 0.955
6.231SerLys: 6.231 ± 0.407
8.539SerLeu: 8.539 ± 0.275
2.308SerMet: 2.308 ± 0.518
3.462SerAsn: 3.462 ± 0.745
2.308SerPro: 2.308 ± 0.21
4.154SerGln: 4.154 ± 0.749
4.154SerArg: 4.154 ± 1.149
6.0SerSer: 6.0 ± 1.911
5.308SerThr: 5.308 ± 1.908
5.77SerVal: 5.77 ± 0.877
0.692SerTrp: 0.692 ± 0.579
2.769SerTyr: 2.769 ± 1.158
0.0SerXaa: 0.0 ± 0.0
Thr
3.693ThrAla: 3.693 ± 0.841
1.154ThrCys: 1.154 ± 0.264
3.231ThrAsp: 3.231 ± 0.593
1.385ThrGlu: 1.385 ± 0.666
2.769ThrPhe: 2.769 ± 0.728
3.923ThrGly: 3.923 ± 0.763
2.539ThrHis: 2.539 ± 0.262
5.077ThrIle: 5.077 ± 0.619
2.539ThrLys: 2.539 ± 1.57
8.308ThrLeu: 8.308 ± 1.34
1.846ThrMet: 1.846 ± 0.39
3.231ThrAsn: 3.231 ± 1.433
3.231ThrPro: 3.231 ± 1.268
3.231ThrGln: 3.231 ± 0.912
1.846ThrArg: 1.846 ± 0.478
5.539ThrSer: 5.539 ± 0.529
6.0ThrThr: 6.0 ± 1.267
4.847ThrVal: 4.847 ± 0.924
1.154ThrTrp: 1.154 ± 0.123
1.616ThrTyr: 1.616 ± 0.343
0.0ThrXaa: 0.0 ± 0.0
Val
3.462ValAla: 3.462 ± 0.548
1.385ValCys: 1.385 ± 0.132
3.231ValAsp: 3.231 ± 0.925
3.0ValGlu: 3.0 ± 0.784
2.308ValPhe: 2.308 ± 0.56
2.308ValGly: 2.308 ± 0.405
1.154ValHis: 1.154 ± 0.362
4.616ValIle: 4.616 ± 1.057
4.385ValLys: 4.385 ± 0.866
4.154ValLeu: 4.154 ± 0.574
3.231ValMet: 3.231 ± 0.795
2.077ValAsn: 2.077 ± 0.675
3.693ValPro: 3.693 ± 0.195
2.077ValGln: 2.077 ± 0.206
4.847ValArg: 4.847 ± 1.048
5.77ValSer: 5.77 ± 0.305
3.693ValThr: 3.693 ± 1.082
3.462ValVal: 3.462 ± 0.723
0.923ValTrp: 0.923 ± 0.534
1.846ValTyr: 1.846 ± 0.95
0.0ValXaa: 0.0 ± 0.0
Trp
0.923TrpAla: 0.923 ± 0.123
0.231TrpCys: 0.231 ± 0.133
0.692TrpAsp: 0.692 ± 0.149
1.385TrpGlu: 1.385 ± 0.298
0.0TrpPhe: 0.0 ± 0.0
1.385TrpGly: 1.385 ± 0.345
0.231TrpHis: 0.231 ± 0.236
1.616TrpIle: 1.616 ± 0.028
1.846TrpLys: 1.846 ± 0.582
2.769TrpLeu: 2.769 ± 0.377
1.154TrpMet: 1.154 ± 0.46
0.923TrpAsn: 0.923 ± 0.123
0.692TrpPro: 0.692 ± 0.268
0.231TrpGln: 0.231 ± 0.133
0.462TrpArg: 0.462 ± 0.267
0.462TrpSer: 0.462 ± 0.145
0.462TrpThr: 0.462 ± 0.267
1.616TrpVal: 1.616 ± 0.65
0.231TrpTrp: 0.231 ± 0.272
0.462TrpTyr: 0.462 ± 0.145
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.385TyrAla: 1.385 ± 0.486
0.462TyrCys: 0.462 ± 0.267
1.846TyrAsp: 1.846 ± 0.14
1.154TyrGlu: 1.154 ± 0.263
1.154TyrPhe: 1.154 ± 0.362
1.616TyrGly: 1.616 ± 0.028
1.846TyrHis: 1.846 ± 0.582
1.385TyrIle: 1.385 ± 0.132
1.616TyrLys: 1.616 ± 0.397
3.693TyrLeu: 3.693 ± 0.971
1.154TyrMet: 1.154 ± 0.263
2.077TyrAsn: 2.077 ± 0.17
2.077TyrPro: 2.077 ± 0.272
2.539TyrGln: 2.539 ± 0.098
0.692TyrArg: 0.692 ± 0.49
2.308TyrSer: 2.308 ± 0.525
2.077TyrThr: 2.077 ± 0.602
1.846TyrVal: 1.846 ± 0.246
0.692TyrTrp: 0.692 ± 0.149
1.846TyrTyr: 1.846 ± 0.83
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (4334 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski