Amino acid dipepetide frequency for Sclerotinia sclerotiorum negative-stranded RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.592AlaAla: 4.592 ± 2.641
1.312AlaCys: 1.312 ± 0.968
2.296AlaAsp: 2.296 ± 1.014
2.624AlaGlu: 2.624 ± 1.988
2.952AlaPhe: 2.952 ± 0.997
2.296AlaGly: 2.296 ± 1.379
1.968AlaHis: 1.968 ± 0.497
5.248AlaIle: 5.248 ± 1.012
2.296AlaLys: 2.296 ± 0.899
7.215AlaLeu: 7.215 ± 3.743
0.984AlaMet: 0.984 ± 0.445
3.28AlaAsn: 3.28 ± 0.661
1.968AlaPro: 1.968 ± 0.446
0.984AlaGln: 0.984 ± 0.934
2.624AlaArg: 2.624 ± 0.767
3.608AlaSer: 3.608 ± 1.166
4.592AlaThr: 4.592 ± 0.697
3.608AlaVal: 3.608 ± 1.099
0.328AlaTrp: 0.328 ± 0.171
0.984AlaTyr: 0.984 ± 1.029
0.0AlaXaa: 0.0 ± 0.0
Cys
0.984CysAla: 0.984 ± 0.581
0.0CysCys: 0.0 ± 0.0
0.656CysAsp: 0.656 ± 0.464
0.656CysGlu: 0.656 ± 0.477
0.656CysPhe: 0.656 ± 0.342
0.328CysGly: 0.328 ± 0.171
0.656CysHis: 0.656 ± 0.787
0.656CysIle: 0.656 ± 0.342
1.312CysLys: 1.312 ± 0.489
1.64CysLeu: 1.64 ± 0.56
0.328CysMet: 0.328 ± 0.54
0.328CysAsn: 0.328 ± 0.474
1.312CysPro: 1.312 ± 0.489
0.328CysGln: 0.328 ± 0.54
0.656CysArg: 0.656 ± 0.484
0.984CysSer: 0.984 ± 0.445
0.984CysThr: 0.984 ± 0.445
0.656CysVal: 0.656 ± 0.477
0.328CysTrp: 0.328 ± 0.171
0.328CysTyr: 0.328 ± 0.171
0.0CysXaa: 0.0 ± 0.0
Asp
3.936AspAla: 3.936 ± 0.795
0.328AspCys: 0.328 ± 0.171
1.64AspAsp: 1.64 ± 0.906
3.28AspGlu: 3.28 ± 0.793
1.64AspPhe: 1.64 ± 0.608
1.64AspGly: 1.64 ± 0.608
0.328AspHis: 0.328 ± 0.171
4.592AspIle: 4.592 ± 1.779
4.264AspLys: 4.264 ± 0.92
8.199AspLeu: 8.199 ± 0.315
0.656AspMet: 0.656 ± 0.342
2.624AspAsn: 2.624 ± 0.445
1.968AspPro: 1.968 ± 0.677
2.952AspGln: 2.952 ± 2.024
3.28AspArg: 3.28 ± 1.344
3.28AspSer: 3.28 ± 1.219
2.952AspThr: 2.952 ± 1.592
3.936AspVal: 3.936 ± 0.711
0.328AspTrp: 0.328 ± 0.171
2.624AspTyr: 2.624 ± 0.995
0.0AspXaa: 0.0 ± 0.0
Glu
3.28GluAla: 3.28 ± 1.767
0.328GluCys: 0.328 ± 0.171
2.624GluAsp: 2.624 ± 1.743
2.624GluGlu: 2.624 ± 2.038
3.608GluPhe: 3.608 ± 1.345
0.328GluGly: 0.328 ± 0.171
0.656GluHis: 0.656 ± 0.342
6.888GluIle: 6.888 ± 1.263
3.608GluLys: 3.608 ± 0.704
8.199GluLeu: 8.199 ± 2.21
0.656GluMet: 0.656 ± 0.443
2.952GluAsn: 2.952 ± 0.747
2.296GluPro: 2.296 ± 0.692
1.968GluGln: 1.968 ± 0.462
4.92GluArg: 4.92 ± 1.238
6.888GluSer: 6.888 ± 0.773
2.952GluThr: 2.952 ± 1.609
3.28GluVal: 3.28 ± 1.034
0.328GluTrp: 0.328 ± 0.171
1.968GluTyr: 1.968 ± 1.311
0.0GluXaa: 0.0 ± 0.0
Phe
1.968PheAla: 1.968 ± 2.058
0.328PheCys: 0.328 ± 0.171
2.624PheAsp: 2.624 ± 0.927
3.936PheGlu: 3.936 ± 1.269
2.296PhePhe: 2.296 ± 0.489
1.968PheGly: 1.968 ± 0.889
0.656PheHis: 0.656 ± 0.342
1.64PheIle: 1.64 ± 0.582
3.936PheLys: 3.936 ± 1.048
2.952PheLeu: 2.952 ± 0.488
0.984PheMet: 0.984 ± 0.445
1.968PheAsn: 1.968 ± 1.048
1.968PhePro: 1.968 ± 0.562
2.952PheGln: 2.952 ± 0.999
1.312PheArg: 1.312 ± 1.13
6.56PheSer: 6.56 ± 0.91
1.312PheThr: 1.312 ± 0.498
2.296PheVal: 2.296 ± 0.558
0.656PheTrp: 0.656 ± 0.342
0.984PheTyr: 0.984 ± 0.847
0.0PheXaa: 0.0 ± 0.0
Gly
1.968GlyAla: 1.968 ± 0.889
0.656GlyCys: 0.656 ± 0.477
2.296GlyAsp: 2.296 ± 1.198
2.952GlyGlu: 2.952 ± 0.631
1.64GlyPhe: 1.64 ± 0.582
2.296GlyGly: 2.296 ± 0.814
0.656GlyHis: 0.656 ± 0.342
3.608GlyIle: 3.608 ± 0.872
1.968GlyLys: 1.968 ± 0.817
4.592GlyLeu: 4.592 ± 1.172
1.312GlyMet: 1.312 ± 1.208
2.624GlyAsn: 2.624 ± 0.719
0.656GlyPro: 0.656 ± 0.342
0.656GlyGln: 0.656 ± 0.484
0.984GlyArg: 0.984 ± 0.514
2.952GlySer: 2.952 ± 1.254
2.952GlyThr: 2.952 ± 0.766
3.608GlyVal: 3.608 ± 1.787
0.0GlyTrp: 0.0 ± 0.0
2.296GlyTyr: 2.296 ± 0.845
0.0GlyXaa: 0.0 ± 0.0
His
2.952HisAla: 2.952 ± 1.334
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.656HisGlu: 0.656 ± 0.484
0.984HisPhe: 0.984 ± 0.475
0.984HisGly: 0.984 ± 0.445
0.328HisHis: 0.328 ± 0.54
1.312HisIle: 1.312 ± 0.685
0.984HisLys: 0.984 ± 0.484
2.624HisLeu: 2.624 ± 1.04
0.328HisMet: 0.328 ± 0.54
1.312HisAsn: 1.312 ± 0.685
1.312HisPro: 1.312 ± 0.685
0.0HisGln: 0.0 ± 0.0
2.296HisArg: 2.296 ± 0.366
1.64HisSer: 1.64 ± 0.953
1.312HisThr: 1.312 ± 0.489
1.312HisVal: 1.312 ± 0.476
0.328HisTrp: 0.328 ± 0.171
0.656HisTyr: 0.656 ± 0.342
0.0HisXaa: 0.0 ± 0.0
Ile
2.952IleAla: 2.952 ± 1.961
3.28IleCys: 3.28 ± 1.381
4.264IleAsp: 4.264 ± 1.051
3.608IleGlu: 3.608 ± 1.004
4.592IlePhe: 4.592 ± 0.316
2.952IleGly: 2.952 ± 0.704
0.984IleHis: 0.984 ± 0.514
3.608IleIle: 3.608 ± 1.499
4.592IleLys: 4.592 ± 1.792
7.871IleLeu: 7.871 ± 1.817
1.312IleMet: 1.312 ± 0.542
4.592IleAsn: 4.592 ± 0.92
5.904IlePro: 5.904 ± 0.854
1.968IleGln: 1.968 ± 0.462
3.936IleArg: 3.936 ± 1.247
10.167IleSer: 10.167 ± 1.87
2.952IleThr: 2.952 ± 1.539
3.608IleVal: 3.608 ± 1.044
0.0IleTrp: 0.0 ± 0.0
1.312IleTyr: 1.312 ± 0.542
0.0IleXaa: 0.0 ± 0.0
Lys
1.968LysAla: 1.968 ± 0.969
0.328LysCys: 0.328 ± 0.171
3.28LysAsp: 3.28 ± 1.771
4.92LysGlu: 4.92 ± 1.776
2.624LysPhe: 2.624 ± 0.995
2.624LysGly: 2.624 ± 0.701
1.312LysHis: 1.312 ± 0.542
4.592LysIle: 4.592 ± 0.776
4.592LysLys: 4.592 ± 1.814
5.904LysLeu: 5.904 ± 0.883
0.984LysMet: 0.984 ± 0.464
2.952LysAsn: 2.952 ± 0.541
3.608LysPro: 3.608 ± 1.604
3.608LysGln: 3.608 ± 1.044
2.952LysArg: 2.952 ± 0.841
3.608LysSer: 3.608 ± 1.383
4.264LysThr: 4.264 ± 0.764
1.968LysVal: 1.968 ± 1.045
0.984LysTrp: 0.984 ± 0.445
1.968LysTyr: 1.968 ± 1.159
0.0LysXaa: 0.0 ± 0.0
Leu
5.248LeuAla: 5.248 ± 1.012
0.984LeuCys: 0.984 ± 0.445
6.232LeuAsp: 6.232 ± 0.977
4.92LeuGlu: 4.92 ± 1.904
3.608LeuPhe: 3.608 ± 1.437
4.264LeuGly: 4.264 ± 0.76
2.952LeuHis: 2.952 ± 0.75
9.839LeuIle: 9.839 ± 1.27
7.215LeuLys: 7.215 ± 0.827
9.839LeuLeu: 9.839 ± 1.056
0.984LeuMet: 0.984 ± 0.484
2.624LeuAsn: 2.624 ± 1.724
6.888LeuPro: 6.888 ± 1.569
3.28LeuGln: 3.28 ± 0.784
8.527LeuArg: 8.527 ± 2.945
10.167LeuSer: 10.167 ± 1.65
9.511LeuThr: 9.511 ± 1.778
5.904LeuVal: 5.904 ± 1.219
1.312LeuTrp: 1.312 ± 0.685
4.592LeuTyr: 4.592 ± 1.968
0.0LeuXaa: 0.0 ± 0.0
Met
1.312MetAla: 1.312 ± 0.685
0.656MetCys: 0.656 ± 0.464
0.984MetAsp: 0.984 ± 0.581
1.312MetGlu: 1.312 ± 0.498
0.984MetPhe: 0.984 ± 1.029
0.656MetGly: 0.656 ± 0.464
0.656MetHis: 0.656 ± 0.342
1.968MetIle: 1.968 ± 0.541
0.656MetLys: 0.656 ± 0.342
0.656MetLeu: 0.656 ± 0.342
0.656MetMet: 0.656 ± 0.342
0.328MetAsn: 0.328 ± 0.171
1.64MetPro: 1.64 ± 0.654
1.312MetGln: 1.312 ± 1.131
0.984MetArg: 0.984 ± 0.484
2.952MetSer: 2.952 ± 1.273
1.64MetThr: 1.64 ± 0.856
0.656MetVal: 0.656 ± 0.477
0.328MetTrp: 0.328 ± 0.171
1.64MetTyr: 1.64 ± 0.462
0.0MetXaa: 0.0 ± 0.0
Asn
3.936AsnAla: 3.936 ± 0.964
0.656AsnCys: 0.656 ± 0.79
3.28AsnAsp: 3.28 ± 0.626
2.296AsnGlu: 2.296 ± 0.794
1.64AsnPhe: 1.64 ± 0.856
0.984AsnGly: 0.984 ± 0.514
1.968AsnHis: 1.968 ± 0.817
2.624AsnIle: 2.624 ± 1.172
2.296AsnLys: 2.296 ± 0.489
5.576AsnLeu: 5.576 ± 1.062
1.312AsnMet: 1.312 ± 0.592
1.968AsnAsn: 1.968 ± 1.166
1.968AsnPro: 1.968 ± 1.457
1.968AsnGln: 1.968 ± 0.783
2.296AsnArg: 2.296 ± 1.841
4.264AsnSer: 4.264 ± 1.186
3.608AsnThr: 3.608 ± 1.403
1.312AsnVal: 1.312 ± 1.102
0.656AsnTrp: 0.656 ± 0.477
2.296AsnTyr: 2.296 ± 0.489
0.0AsnXaa: 0.0 ± 0.0
Pro
2.624ProAla: 2.624 ± 0.806
0.328ProCys: 0.328 ± 0.171
2.952ProAsp: 2.952 ± 0.997
4.592ProGlu: 4.592 ± 0.884
1.312ProPhe: 1.312 ± 0.489
3.608ProGly: 3.608 ± 1.551
0.984ProHis: 0.984 ± 0.514
4.264ProIle: 4.264 ± 1.055
1.968ProLys: 1.968 ± 0.887
3.936ProLeu: 3.936 ± 1.601
1.64ProMet: 1.64 ± 0.429
2.952ProAsn: 2.952 ± 0.772
2.952ProPro: 2.952 ± 0.944
2.952ProGln: 2.952 ± 1.239
1.312ProArg: 1.312 ± 0.624
5.248ProSer: 5.248 ± 1.988
3.28ProThr: 3.28 ± 1.199
1.312ProVal: 1.312 ± 0.542
0.984ProTrp: 0.984 ± 0.514
1.312ProTyr: 1.312 ± 0.476
0.0ProXaa: 0.0 ± 0.0
Gln
1.968GlnAla: 1.968 ± 0.947
0.328GlnCys: 0.328 ± 0.171
2.624GlnAsp: 2.624 ± 1.671
1.968GlnGlu: 1.968 ± 0.462
1.968GlnPhe: 1.968 ± 1.262
2.296GlnGly: 2.296 ± 0.622
0.656GlnHis: 0.656 ± 1.125
1.968GlnIle: 1.968 ± 0.767
2.296GlnLys: 2.296 ± 0.781
4.592GlnLeu: 4.592 ± 1.643
0.656GlnMet: 0.656 ± 0.434
0.984GlnAsn: 0.984 ± 0.675
1.312GlnPro: 1.312 ± 1.093
2.296GlnGln: 2.296 ± 0.521
0.984GlnArg: 0.984 ± 1.029
3.608GlnSer: 3.608 ± 1.009
2.624GlnThr: 2.624 ± 1.415
1.312GlnVal: 1.312 ± 0.542
0.328GlnTrp: 0.328 ± 0.54
1.312GlnTyr: 1.312 ± 0.542
0.0GlnXaa: 0.0 ± 0.0
Arg
2.952ArgAla: 2.952 ± 0.541
0.984ArgCys: 0.984 ± 0.514
2.624ArgAsp: 2.624 ± 1.232
3.608ArgGlu: 3.608 ± 1.317
1.968ArgPhe: 1.968 ± 0.889
1.64ArgGly: 1.64 ± 0.856
1.968ArgHis: 1.968 ± 0.562
3.936ArgIle: 3.936 ± 1.17
3.28ArgLys: 3.28 ± 0.41
7.215ArgLeu: 7.215 ± 1.194
1.968ArgMet: 1.968 ± 0.889
2.296ArgAsn: 2.296 ± 1.604
1.64ArgPro: 1.64 ± 0.61
1.312ArgGln: 1.312 ± 0.561
6.56ArgArg: 6.56 ± 1.16
3.936ArgSer: 3.936 ± 1.376
4.592ArgThr: 4.592 ± 0.697
1.312ArgVal: 1.312 ± 1.198
0.984ArgTrp: 0.984 ± 0.514
2.296ArgTyr: 2.296 ± 0.919
0.0ArgXaa: 0.0 ± 0.0
Ser
5.248SerAla: 5.248 ± 2.122
0.656SerCys: 0.656 ± 0.477
5.248SerAsp: 5.248 ± 0.791
4.592SerGlu: 4.592 ± 1.079
3.608SerPhe: 3.608 ± 1.196
6.232SerGly: 6.232 ± 1.7
2.624SerHis: 2.624 ± 0.765
7.543SerIle: 7.543 ± 0.71
3.608SerLys: 3.608 ± 0.704
9.183SerLeu: 9.183 ± 2.653
1.968SerMet: 1.968 ± 0.523
4.264SerAsn: 4.264 ± 1.464
5.576SerPro: 5.576 ± 1.41
3.608SerGln: 3.608 ± 0.515
5.904SerArg: 5.904 ± 1.241
7.215SerSer: 7.215 ± 1.219
7.871SerThr: 7.871 ± 1.249
4.92SerVal: 4.92 ± 0.652
0.656SerTrp: 0.656 ± 0.464
2.952SerTyr: 2.952 ± 1.279
0.0SerXaa: 0.0 ± 0.0
Thr
2.952ThrAla: 2.952 ± 1.649
1.64ThrCys: 1.64 ± 0.582
3.936ThrAsp: 3.936 ± 0.525
5.248ThrGlu: 5.248 ± 1.626
1.968ThrPhe: 1.968 ± 0.876
1.64ThrGly: 1.64 ± 0.953
0.656ThrHis: 0.656 ± 0.342
4.264ThrIle: 4.264 ± 1.237
5.904ThrLys: 5.904 ± 0.766
7.543ThrLeu: 7.543 ± 1.338
2.624ThrMet: 2.624 ± 0.991
3.936ThrAsn: 3.936 ± 1.894
1.968ThrPro: 1.968 ± 0.767
2.624ThrGln: 2.624 ± 0.445
3.28ThrArg: 3.28 ± 0.844
6.888ThrSer: 6.888 ± 1.086
4.264ThrThr: 4.264 ± 2.884
2.624ThrVal: 2.624 ± 0.484
0.328ThrTrp: 0.328 ± 0.171
2.952ThrTyr: 2.952 ± 1.117
0.0ThrXaa: 0.0 ± 0.0
Val
2.624ValAla: 2.624 ± 0.784
0.984ValCys: 0.984 ± 0.948
3.28ValAsp: 3.28 ± 0.925
4.592ValGlu: 4.592 ± 2.043
3.28ValPhe: 3.28 ± 1.807
1.64ValGly: 1.64 ± 0.856
0.984ValHis: 0.984 ± 0.484
2.952ValIle: 2.952 ± 1.628
1.64ValLys: 1.64 ± 0.856
7.215ValLeu: 7.215 ± 1.302
0.984ValMet: 0.984 ± 1.029
1.968ValAsn: 1.968 ± 0.91
2.624ValPro: 2.624 ± 1.909
0.656ValGln: 0.656 ± 0.477
1.312ValArg: 1.312 ± 0.561
3.936ValSer: 3.936 ± 0.837
3.28ValThr: 3.28 ± 1.233
1.312ValVal: 1.312 ± 0.685
1.312ValTrp: 1.312 ± 0.569
0.984ValTyr: 0.984 ± 0.514
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.984TrpAsp: 0.984 ± 0.445
0.656TrpGlu: 0.656 ± 1.064
0.328TrpPhe: 0.328 ± 0.171
0.328TrpGly: 0.328 ± 0.171
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.656TrpLys: 0.656 ± 0.342
0.656TrpLeu: 0.656 ± 0.342
0.0TrpMet: 0.0 ± 0.0
1.64TrpAsn: 1.64 ± 0.856
0.984TrpPro: 0.984 ± 0.514
0.328TrpGln: 0.328 ± 0.171
0.984TrpArg: 0.984 ± 0.514
0.328TrpSer: 0.328 ± 0.171
0.984TrpThr: 0.984 ± 0.514
1.312TrpVal: 1.312 ± 0.476
0.328TrpTrp: 0.328 ± 0.171
0.328TrpTyr: 0.328 ± 0.563
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.296TyrAla: 2.296 ± 0.816
0.0TyrCys: 0.0 ± 0.0
2.624TyrAsp: 2.624 ± 0.995
1.312TyrGlu: 1.312 ± 0.476
1.64TyrPhe: 1.64 ± 0.654
1.968TyrGly: 1.968 ± 0.91
0.328TyrHis: 0.328 ± 0.171
2.952TyrIle: 2.952 ± 0.704
1.968TyrLys: 1.968 ± 0.701
3.28TyrLeu: 3.28 ± 0.932
1.312TyrMet: 1.312 ± 0.685
1.312TyrAsn: 1.312 ± 0.685
1.968TyrPro: 1.968 ± 0.462
0.656TyrGln: 0.656 ± 0.342
1.968TyrArg: 1.968 ± 0.705
5.248TyrSer: 5.248 ± 1.356
1.312TyrThr: 1.312 ± 0.685
1.312TyrVal: 1.312 ± 1.102
0.328TyrTrp: 0.328 ± 0.171
2.624TyrTyr: 2.624 ± 0.978
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3050 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski