Amino acid dipepetide frequency for Alloscardovia omnicolens F0580

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.708AlaAla: 10.708 ± 0.21
0.889AlaCys: 0.889 ± 0.047
6.132AlaAsp: 6.132 ± 0.112
5.195AlaGlu: 5.195 ± 0.111
3.598AlaPhe: 3.598 ± 0.079
7.428AlaGly: 7.428 ± 0.131
2.851AlaHis: 2.851 ± 0.094
5.555AlaIle: 5.555 ± 0.125
3.836AlaLys: 3.836 ± 0.1
9.996AlaLeu: 9.996 ± 0.176
2.788AlaMet: 2.788 ± 0.082
3.074AlaAsn: 3.074 ± 0.072
3.393AlaPro: 3.393 ± 0.092
6.051AlaGln: 6.051 ± 0.128
5.925AlaArg: 5.925 ± 0.136
6.193AlaSer: 6.193 ± 0.122
5.278AlaThr: 5.278 ± 0.113
8.462AlaVal: 8.462 ± 0.154
1.375AlaTrp: 1.375 ± 0.053
2.775AlaTyr: 2.775 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
1.065CysAla: 1.065 ± 0.049
0.088CysCys: 0.088 ± 0.014
0.477CysAsp: 0.477 ± 0.027
0.509CysGlu: 0.509 ± 0.029
0.293CysPhe: 0.293 ± 0.025
0.785CysGly: 0.785 ± 0.045
0.214CysHis: 0.214 ± 0.021
0.506CysIle: 0.506 ± 0.036
0.236CysLys: 0.236 ± 0.022
0.63CysLeu: 0.63 ± 0.034
0.255CysMet: 0.255 ± 0.023
0.239CysAsn: 0.239 ± 0.023
0.349CysPro: 0.349 ± 0.027
0.203CysGln: 0.203 ± 0.02
0.337CysArg: 0.337 ± 0.023
0.574CysSer: 0.574 ± 0.035
0.5CysThr: 0.5 ± 0.032
0.777CysVal: 0.777 ± 0.04
0.119CysTrp: 0.119 ± 0.015
0.226CysTyr: 0.226 ± 0.024
0.0CysXaa: 0.0 ± 0.0
Asp
5.95AspAla: 5.95 ± 0.114
0.481AspCys: 0.481 ± 0.03
3.941AspAsp: 3.941 ± 0.125
4.546AspGlu: 4.546 ± 0.125
2.645AspPhe: 2.645 ± 0.073
4.604AspGly: 4.604 ± 0.103
0.982AspHis: 0.982 ± 0.044
3.849AspIle: 3.849 ± 0.086
2.725AspLys: 2.725 ± 0.074
4.623AspLeu: 4.623 ± 0.107
1.643AspMet: 1.643 ± 0.053
2.422AspAsn: 2.422 ± 0.071
2.382AspPro: 2.382 ± 0.078
1.45AspGln: 1.45 ± 0.05
2.399AspArg: 2.399 ± 0.085
3.874AspSer: 3.874 ± 0.083
3.277AspThr: 3.277 ± 0.083
4.988AspVal: 4.988 ± 0.094
0.831AspTrp: 0.831 ± 0.04
2.045AspTyr: 2.045 ± 0.062
0.0AspXaa: 0.0 ± 0.0
Glu
5.678GluAla: 5.678 ± 0.123
0.377GluCys: 0.377 ± 0.028
3.416GluAsp: 3.416 ± 0.084
3.918GluGlu: 3.918 ± 0.111
2.022GluPhe: 2.022 ± 0.061
3.826GluGly: 3.826 ± 0.1
1.723GluHis: 1.723 ± 0.063
3.305GluIle: 3.305 ± 0.093
3.386GluLys: 3.386 ± 0.095
5.329GluLeu: 5.329 ± 0.121
1.555GluMet: 1.555 ± 0.053
2.758GluAsn: 2.758 ± 0.077
2.039GluPro: 2.039 ± 0.072
3.089GluGln: 3.089 ± 0.092
3.765GluArg: 3.765 ± 0.112
3.447GluSer: 3.447 ± 0.078
2.922GluThr: 2.922 ± 0.075
3.945GluVal: 3.945 ± 0.099
0.624GluTrp: 0.624 ± 0.034
1.982GluTyr: 1.982 ± 0.064
0.0GluXaa: 0.0 ± 0.0
Phe
4.027PheAla: 4.027 ± 0.099
0.335PheCys: 0.335 ± 0.027
2.528PheAsp: 2.528 ± 0.073
2.327PheGlu: 2.327 ± 0.069
1.586PhePhe: 1.586 ± 0.074
3.137PheGly: 3.137 ± 0.096
0.776PheHis: 0.776 ± 0.044
2.434PheIle: 2.434 ± 0.089
1.344PheLys: 1.344 ± 0.052
3.056PheLeu: 3.056 ± 0.101
1.025PheMet: 1.025 ± 0.049
1.584PheAsn: 1.584 ± 0.055
1.279PhePro: 1.279 ± 0.049
0.931PheGln: 0.931 ± 0.044
1.342PheArg: 1.342 ± 0.048
2.694PheSer: 2.694 ± 0.079
2.505PheThr: 2.505 ± 0.073
2.972PheVal: 2.972 ± 0.087
0.469PheTrp: 0.469 ± 0.034
1.162PheTyr: 1.162 ± 0.051
0.0PheXaa: 0.0 ± 0.0
Gly
6.52GlyAla: 6.52 ± 0.127
0.613GlyCys: 0.613 ± 0.033
3.631GlyAsp: 3.631 ± 0.094
4.175GlyGlu: 4.175 ± 0.094
3.075GlyPhe: 3.075 ± 0.088
4.822GlyGly: 4.822 ± 0.119
1.517GlyHis: 1.517 ± 0.058
4.854GlyIle: 4.854 ± 0.109
3.64GlyLys: 3.64 ± 0.1
6.452GlyLeu: 6.452 ± 0.116
1.928GlyMet: 1.928 ± 0.064
2.589GlyAsn: 2.589 ± 0.075
1.844GlyPro: 1.844 ± 0.061
2.426GlyGln: 2.426 ± 0.072
3.407GlyArg: 3.407 ± 0.091
5.054GlySer: 5.054 ± 0.089
4.485GlyThr: 4.485 ± 0.078
6.0GlyVal: 6.0 ± 0.116
1.078GlyTrp: 1.078 ± 0.056
2.539GlyTyr: 2.539 ± 0.07
0.0GlyXaa: 0.0 ± 0.0
His
2.384HisAla: 2.384 ± 0.068
0.193HisCys: 0.193 ± 0.022
1.496HisAsp: 1.496 ± 0.055
1.455HisGlu: 1.455 ± 0.054
0.776HisPhe: 0.776 ± 0.04
1.712HisGly: 1.712 ± 0.056
0.552HisHis: 0.552 ± 0.036
1.668HisIle: 1.668 ± 0.057
1.005HisLys: 1.005 ± 0.045
1.664HisLeu: 1.664 ± 0.063
0.651HisMet: 0.651 ± 0.037
1.12HisAsn: 1.12 ± 0.044
1.174HisPro: 1.174 ± 0.055
0.643HisGln: 0.643 ± 0.034
1.256HisArg: 1.256 ± 0.047
1.492HisSer: 1.492 ± 0.048
1.591HisThr: 1.591 ± 0.053
1.934HisVal: 1.934 ± 0.066
0.276HisTrp: 0.276 ± 0.025
0.67HisTyr: 0.67 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
7.045IleAla: 7.045 ± 0.138
0.555IleCys: 0.555 ± 0.03
4.177IleAsp: 4.177 ± 0.08
3.795IleGlu: 3.795 ± 0.088
2.44IlePhe: 2.44 ± 0.089
4.228IleGly: 4.228 ± 0.103
1.298IleHis: 1.298 ± 0.05
4.096IleIle: 4.096 ± 0.116
2.08IleLys: 2.08 ± 0.071
4.692IleLeu: 4.692 ± 0.106
1.513IleMet: 1.513 ± 0.052
2.35IleAsn: 2.35 ± 0.071
2.909IlePro: 2.909 ± 0.079
1.676IleGln: 1.676 ± 0.063
2.895IleArg: 2.895 ± 0.071
4.381IleSer: 4.381 ± 0.096
3.757IleThr: 3.757 ± 0.085
5.17IleVal: 5.17 ± 0.106
0.561IleTrp: 0.561 ± 0.031
1.429IleTyr: 1.429 ± 0.041
0.0IleXaa: 0.0 ± 0.0
Lys
4.194LysAla: 4.194 ± 0.114
0.153LysCys: 0.153 ± 0.016
2.568LysAsp: 2.568 ± 0.1
2.48LysGlu: 2.48 ± 0.077
1.243LysPhe: 1.243 ± 0.053
2.443LysGly: 2.443 ± 0.076
0.969LysHis: 0.969 ± 0.041
2.468LysIle: 2.468 ± 0.085
2.884LysLys: 2.884 ± 0.096
3.585LysLeu: 3.585 ± 0.086
1.078LysMet: 1.078 ± 0.049
2.453LysAsn: 2.453 ± 0.076
2.009LysPro: 2.009 ± 0.071
1.771LysGln: 1.771 ± 0.053
2.405LysArg: 2.405 ± 0.078
2.844LysSer: 2.844 ± 0.082
2.907LysThr: 2.907 ± 0.084
2.853LysVal: 2.853 ± 0.081
0.473LysTrp: 0.473 ± 0.026
1.241LysTyr: 1.241 ± 0.056
0.0LysXaa: 0.0 ± 0.0
Leu
8.956LeuAla: 8.956 ± 0.16
0.913LeuCys: 0.913 ± 0.048
5.49LeuAsp: 5.49 ± 0.117
4.701LeuGlu: 4.701 ± 0.117
3.227LeuPhe: 3.227 ± 0.099
6.568LeuGly: 6.568 ± 0.115
2.085LeuHis: 2.085 ± 0.069
5.448LeuIle: 5.448 ± 0.129
3.552LeuLys: 3.552 ± 0.082
7.442LeuLeu: 7.442 ± 0.152
2.212LeuMet: 2.212 ± 0.07
3.721LeuAsn: 3.721 ± 0.08
3.968LeuPro: 3.968 ± 0.107
2.568LeuGln: 2.568 ± 0.061
4.745LeuArg: 4.745 ± 0.108
6.762LeuSer: 6.762 ± 0.126
5.594LeuThr: 5.594 ± 0.119
6.092LeuVal: 6.092 ± 0.128
1.099LeuTrp: 1.099 ± 0.055
2.26LeuTyr: 2.26 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
2.551MetAla: 2.551 ± 0.07
0.289MetCys: 0.289 ± 0.024
1.258MetAsp: 1.258 ± 0.05
1.147MetGlu: 1.147 ± 0.048
0.808MetPhe: 0.808 ± 0.041
1.779MetGly: 1.779 ± 0.064
0.653MetHis: 0.653 ± 0.035
1.499MetIle: 1.499 ± 0.058
1.314MetLys: 1.314 ± 0.053
2.375MetLeu: 2.375 ± 0.073
0.697MetMet: 0.697 ± 0.042
1.256MetAsn: 1.256 ± 0.051
1.218MetPro: 1.218 ± 0.049
0.883MetGln: 0.883 ± 0.039
1.739MetArg: 1.739 ± 0.057
2.078MetSer: 2.078 ± 0.067
1.802MetThr: 1.802 ± 0.061
1.79MetVal: 1.79 ± 0.06
0.306MetTrp: 0.306 ± 0.025
0.689MetTyr: 0.689 ± 0.037
0.0MetXaa: 0.0 ± 0.0
Asn
4.054AsnAla: 4.054 ± 0.095
0.262AsnCys: 0.262 ± 0.024
2.151AsnAsp: 2.151 ± 0.068
2.198AsnGlu: 2.198 ± 0.076
1.446AsnPhe: 1.446 ± 0.057
2.947AsnGly: 2.947 ± 0.085
0.762AsnHis: 0.762 ± 0.037
2.353AsnIle: 2.353 ± 0.074
1.8AsnLys: 1.8 ± 0.065
3.254AsnLeu: 3.254 ± 0.077
1.051AsnMet: 1.051 ± 0.045
1.879AsnAsn: 1.879 ± 0.072
2.398AsnPro: 2.398 ± 0.062
1.467AsnGln: 1.467 ± 0.062
2.059AsnArg: 2.059 ± 0.066
2.624AsnSer: 2.624 ± 0.081
2.641AsnThr: 2.641 ± 0.074
2.767AsnVal: 2.767 ± 0.082
0.569AsnTrp: 0.569 ± 0.033
1.174AsnTyr: 1.174 ± 0.048
0.0AsnXaa: 0.0 ± 0.0
Pro
3.792ProAla: 3.792 ± 0.088
0.268ProCys: 0.268 ± 0.025
2.679ProAsp: 2.679 ± 0.083
2.8ProGlu: 2.8 ± 0.081
1.547ProPhe: 1.547 ± 0.056
2.61ProGly: 2.61 ± 0.067
1.145ProHis: 1.145 ± 0.05
2.072ProIle: 2.072 ± 0.06
1.27ProLys: 1.27 ± 0.058
3.391ProLeu: 3.391 ± 0.092
0.881ProMet: 0.881 ± 0.047
1.281ProAsn: 1.281 ± 0.049
0.881ProPro: 0.881 ± 0.046
2.051ProGln: 2.051 ± 0.064
1.976ProArg: 1.976 ± 0.073
2.83ProSer: 2.83 ± 0.07
2.52ProThr: 2.52 ± 0.076
3.529ProVal: 3.529 ± 0.078
0.555ProTrp: 0.555 ± 0.035
1.363ProTyr: 1.363 ± 0.051
0.0ProXaa: 0.0 ± 0.0
Gln
4.129GlnAla: 4.129 ± 0.114
0.293GlnCys: 0.293 ± 0.023
1.729GlnAsp: 1.729 ± 0.056
2.286GlnGlu: 2.286 ± 0.074
1.293GlnPhe: 1.293 ± 0.049
2.495GlnGly: 2.495 ± 0.068
0.959GlnHis: 0.959 ± 0.046
2.338GlnIle: 2.338 ± 0.059
1.691GlnLys: 1.691 ± 0.062
3.861GlnLeu: 3.861 ± 0.096
0.94GlnMet: 0.94 ± 0.044
1.494GlnAsn: 1.494 ± 0.07
1.597GlnPro: 1.597 ± 0.059
1.79GlnGln: 1.79 ± 0.076
2.353GlnArg: 2.353 ± 0.071
2.633GlnSer: 2.633 ± 0.079
2.097GlnThr: 2.097 ± 0.062
2.606GlnVal: 2.606 ± 0.078
0.712GlnTrp: 0.712 ± 0.036
1.222GlnTyr: 1.222 ± 0.051
0.0GlnXaa: 0.0 ± 0.0
Arg
5.019ArgAla: 5.019 ± 0.105
0.385ArgCys: 0.385 ± 0.029
3.016ArgAsp: 3.016 ± 0.09
3.602ArgGlu: 3.602 ± 0.09
2.016ArgPhe: 2.016 ± 0.06
3.367ArgGly: 3.367 ± 0.086
1.168ArgHis: 1.168 ± 0.047
3.514ArgIle: 3.514 ± 0.091
2.432ArgLys: 2.432 ± 0.071
4.575ArgLeu: 4.575 ± 0.097
1.543ArgMet: 1.543 ± 0.059
2.001ArgAsn: 2.001 ± 0.069
1.722ArgPro: 1.722 ± 0.071
1.762ArgGln: 1.762 ± 0.064
2.982ArgArg: 2.982 ± 0.106
3.46ArgSer: 3.46 ± 0.084
3.141ArgThr: 3.141 ± 0.089
4.316ArgVal: 4.316 ± 0.101
0.733ArgTrp: 0.733 ± 0.045
1.758ArgTyr: 1.758 ± 0.059
0.0ArgXaa: 0.0 ± 0.0
Ser
7.212SerAla: 7.212 ± 0.155
0.511SerCys: 0.511 ± 0.035
3.922SerAsp: 3.922 ± 0.083
3.786SerGlu: 3.786 ± 0.095
2.691SerPhe: 2.691 ± 0.074
5.04SerGly: 5.04 ± 0.095
1.676SerHis: 1.676 ± 0.056
4.098SerIle: 4.098 ± 0.086
2.547SerLys: 2.547 ± 0.076
5.996SerLeu: 5.996 ± 0.12
1.886SerMet: 1.886 ± 0.062
2.447SerAsn: 2.447 ± 0.069
2.371SerPro: 2.371 ± 0.07
2.844SerGln: 2.844 ± 0.078
3.46SerArg: 3.46 ± 0.091
5.511SerSer: 5.511 ± 0.172
4.447SerThr: 4.447 ± 0.085
5.676SerVal: 5.676 ± 0.116
0.98SerTrp: 0.98 ± 0.048
2.105SerTyr: 2.105 ± 0.072
0.0SerXaa: 0.0 ± 0.0
Thr
6.26ThrAla: 6.26 ± 0.116
0.473ThrCys: 0.473 ± 0.031
3.483ThrAsp: 3.483 ± 0.093
3.06ThrGlu: 3.06 ± 0.077
2.196ThrPhe: 2.196 ± 0.069
4.288ThrGly: 4.288 ± 0.09
1.645ThrHis: 1.645 ± 0.057
3.619ThrIle: 3.619 ± 0.093
2.246ThrLys: 2.246 ± 0.08
5.366ThrLeu: 5.366 ± 0.097
1.377ThrMet: 1.377 ± 0.055
2.128ThrAsn: 2.128 ± 0.057
2.849ThrPro: 2.849 ± 0.081
2.547ThrGln: 2.547 ± 0.081
2.966ThrArg: 2.966 ± 0.085
3.968ThrSer: 3.968 ± 0.092
3.648ThrThr: 3.648 ± 0.1
5.507ThrVal: 5.507 ± 0.124
0.848ThrTrp: 0.848 ± 0.051
1.846ThrTyr: 1.846 ± 0.069
0.0ThrXaa: 0.0 ± 0.0
Val
7.599ValAla: 7.599 ± 0.14
0.869ValCys: 0.869 ± 0.047
4.96ValAsp: 4.96 ± 0.113
4.586ValGlu: 4.586 ± 0.106
2.88ValPhe: 2.88 ± 0.087
5.13ValGly: 5.13 ± 0.11
1.915ValHis: 1.915 ± 0.065
4.858ValIle: 4.858 ± 0.107
3.181ValLys: 3.181 ± 0.099
7.451ValLeu: 7.451 ± 0.129
1.911ValMet: 1.911 ± 0.062
3.097ValAsn: 3.097 ± 0.094
3.472ValPro: 3.472 ± 0.085
2.865ValGln: 2.865 ± 0.075
4.314ValArg: 4.314 ± 0.091
5.707ValSer: 5.707 ± 0.127
4.506ValThr: 4.506 ± 0.105
6.327ValVal: 6.327 ± 0.131
1.013ValTrp: 1.013 ± 0.05
2.11ValTyr: 2.11 ± 0.06
0.0ValXaa: 0.0 ± 0.0
Trp
1.153TrpAla: 1.153 ± 0.051
0.132TrpCys: 0.132 ± 0.015
0.799TrpAsp: 0.799 ± 0.042
0.603TrpGlu: 0.603 ± 0.037
0.513TrpPhe: 0.513 ± 0.039
0.963TrpGly: 0.963 ± 0.043
0.333TrpHis: 0.333 ± 0.024
0.825TrpIle: 0.825 ± 0.04
0.561TrpLys: 0.561 ± 0.038
1.34TrpLeu: 1.34 ± 0.053
0.41TrpMet: 0.41 ± 0.029
0.693TrpAsn: 0.693 ± 0.038
0.36TrpPro: 0.36 ± 0.029
0.642TrpGln: 0.642 ± 0.034
0.754TrpArg: 0.754 ± 0.039
0.961TrpSer: 0.961 ± 0.038
0.768TrpThr: 0.768 ± 0.037
0.797TrpVal: 0.797 ± 0.04
0.31TrpTrp: 0.31 ± 0.027
0.41TrpTyr: 0.41 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.208TyrAla: 3.208 ± 0.083
0.301TyrCys: 0.301 ± 0.022
1.806TyrAsp: 1.806 ± 0.062
1.936TyrGlu: 1.936 ± 0.063
1.218TyrPhe: 1.218 ± 0.05
2.476TyrGly: 2.476 ± 0.076
0.488TyrHis: 0.488 ± 0.033
1.685TyrIle: 1.685 ± 0.065
1.293TyrLys: 1.293 ± 0.05
2.327TyrLeu: 2.327 ± 0.071
0.785TyrMet: 0.785 ± 0.045
1.27TyrAsn: 1.27 ± 0.05
1.229TyrPro: 1.229 ± 0.053
0.864TyrGln: 0.864 ± 0.04
1.43TyrArg: 1.43 ± 0.055
2.118TyrSer: 2.118 ± 0.067
1.938TyrThr: 1.938 ± 0.068
2.241TyrVal: 2.241 ± 0.062
0.394TyrTrp: 0.394 ± 0.028
0.933TyrTyr: 0.933 ± 0.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1649 proteins (522203 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski