Amino acid dipepetide frequency for Desulfallas gibsoniae DSM 7213

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.105AlaAla: 8.105 ± 0.116	1.05AlaCys: 1.05 ± 0.032	4.097AlaAsp: 4.097 ± 0.069	5.221AlaGlu: 5.221 ± 0.075	2.829AlaPhe: 2.829 ± 0.053	7.644AlaGly: 7.644 ± 0.098	1.297AlaHis: 1.297 ± 0.037	5.314AlaIle: 5.314 ± 0.075	4.065AlaLys: 4.065 ± 0.064	8.367AlaLeu: 8.367 ± 0.097	2.411AlaMet: 2.411 ± 0.052	2.738AlaAsn: 2.738 ± 0.053	2.508AlaPro: 2.508 ± 0.05	2.655AlaGln: 2.655 ± 0.052	4.988AlaArg: 4.988 ± 0.076	3.951AlaSer: 3.951 ± 0.056	3.647AlaThr: 3.647 ± 0.069	6.989AlaVal: 6.989 ± 0.092	0.74AlaTrp: 0.74 ± 0.023	2.267AlaTyr: 2.267 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.95CysAla: 0.95 ± 0.028	0.278CysCys: 0.278 ± 0.013	0.599CysAsp: 0.599 ± 0.022	0.592CysGlu: 0.592 ± 0.021	0.502CysPhe: 0.502 ± 0.017	1.381CysGly: 1.381 ± 0.037	0.37CysHis: 0.37 ± 0.017	0.764CysIle: 0.764 ± 0.024	0.572CysLys: 0.572 ± 0.021	1.183CysLeu: 1.183 ± 0.029	0.325CysMet: 0.325 ± 0.014	0.518CysAsn: 0.518 ± 0.018	0.832CysPro: 0.832 ± 0.029	0.416CysGln: 0.416 ± 0.016	0.82CysArg: 0.82 ± 0.027	0.878CysSer: 0.878 ± 0.029	0.662CysThr: 0.662 ± 0.027	0.738CysVal: 0.738 ± 0.026	0.137CysTrp: 0.137 ± 0.011	0.429CysTyr: 0.429 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.743AspAla: 3.743 ± 0.065	0.642AspCys: 0.642 ± 0.023	2.493AspAsp: 2.493 ± 0.05	3.534AspGlu: 3.534 ± 0.055	2.297AspPhe: 2.297 ± 0.046	3.705AspGly: 3.705 ± 0.06	0.891AspHis: 0.891 ± 0.024	4.365AspIle: 4.365 ± 0.069	3.314AspLys: 3.314 ± 0.054	5.225AspLeu: 5.225 ± 0.069	1.558AspMet: 1.558 ± 0.039	2.258AspAsn: 2.258 ± 0.04	2.407AspPro: 2.407 ± 0.051	1.636AspGln: 1.636 ± 0.043	2.901AspArg: 2.901 ± 0.055	2.333AspSer: 2.333 ± 0.044	2.465AspThr: 2.465 ± 0.046	3.667AspVal: 3.667 ± 0.053	0.554AspTrp: 0.554 ± 0.022	2.146AspTyr: 2.146 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.152GluAla: 5.152 ± 0.067	0.62GluCys: 0.62 ± 0.025	3.165GluAsp: 3.165 ± 0.053	4.985GluGlu: 4.985 ± 0.071	2.192GluPhe: 2.192 ± 0.046	4.027GluGly: 4.027 ± 0.055	1.302GluHis: 1.302 ± 0.037	5.285GluIle: 5.285 ± 0.063	5.063GluLys: 5.063 ± 0.078	7.099GluLeu: 7.099 ± 0.086	2.009GluMet: 2.009 ± 0.042	2.982GluAsn: 2.982 ± 0.049	2.19GluPro: 2.19 ± 0.045	3.189GluGln: 3.189 ± 0.06	3.329GluArg: 3.329 ± 0.06	2.799GluSer: 2.799 ± 0.047	3.053GluThr: 3.053 ± 0.05	4.736GluVal: 4.736 ± 0.067	0.593GluTrp: 0.593 ± 0.022	2.175GluTyr: 2.175 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	2.865PheAla: 2.865 ± 0.048	0.589PheCys: 0.589 ± 0.023	2.095PheAsp: 2.095 ± 0.039	2.127PheGlu: 2.127 ± 0.044	1.728PhePhe: 1.728 ± 0.041	2.888PheGly: 2.888 ± 0.042	0.686PheHis: 0.686 ± 0.024	3.04PheIle: 3.04 ± 0.057	2.216PheLys: 2.216 ± 0.046	3.662PheLeu: 3.662 ± 0.06	1.043PheMet: 1.043 ± 0.029	1.978PheAsn: 1.978 ± 0.05	1.494PhePro: 1.494 ± 0.032	1.122PheGln: 1.122 ± 0.028	1.64PheArg: 1.64 ± 0.038	2.465PheSer: 2.465 ± 0.048	2.253PheThr: 2.253 ± 0.041	2.443PheVal: 2.443 ± 0.048	0.453PheTrp: 0.453 ± 0.019	1.551PheTyr: 1.551 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	5.921GlyAla: 5.921 ± 0.091	1.214GlyCys: 1.214 ± 0.032	3.706GlyAsp: 3.706 ± 0.057	4.733GlyGlu: 4.733 ± 0.067	3.173GlyPhe: 3.173 ± 0.062	5.861GlyGly: 5.861 ± 0.094	1.523GlyHis: 1.523 ± 0.035	5.754GlyIle: 5.754 ± 0.072	4.852GlyLys: 4.852 ± 0.066	7.548GlyLeu: 7.548 ± 0.084	2.225GlyMet: 2.225 ± 0.041	2.96GlyAsn: 2.96 ± 0.049	2.228GlyPro: 2.228 ± 0.05	2.876GlyGln: 2.876 ± 0.048	4.014GlyArg: 4.014 ± 0.06	4.085GlySer: 4.085 ± 0.061	4.052GlyThr: 4.052 ± 0.058	5.73GlyVal: 5.73 ± 0.08	0.849GlyTrp: 0.849 ± 0.031	3.08GlyTyr: 3.08 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.308HisAla: 1.308 ± 0.032	0.317HisCys: 0.317 ± 0.014	0.932HisAsp: 0.932 ± 0.025	1.022HisGlu: 1.022 ± 0.03	0.83HisPhe: 0.83 ± 0.028	1.483HisGly: 1.483 ± 0.035	0.477HisHis: 0.477 ± 0.017	1.395HisIle: 1.395 ± 0.032	0.94HisLys: 0.94 ± 0.025	1.86HisLeu: 1.86 ± 0.044	0.485HisMet: 0.485 ± 0.019	0.852HisAsn: 0.852 ± 0.027	1.089HisPro: 1.089 ± 0.028	0.698HisGln: 0.698 ± 0.02	1.098HisArg: 1.098 ± 0.034	1.03HisSer: 1.03 ± 0.027	0.971HisThr: 0.971 ± 0.029	1.16HisVal: 1.16 ± 0.031	0.224HisTrp: 0.224 ± 0.013	0.777HisTyr: 0.777 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.735IleAla: 5.735 ± 0.08	0.962IleCys: 0.962 ± 0.033	3.931IleAsp: 3.931 ± 0.051	4.353IleGlu: 4.353 ± 0.061	2.827IlePhe: 2.827 ± 0.052	4.728IleGly: 4.728 ± 0.069	1.242IleHis: 1.242 ± 0.031	5.67IleIle: 5.67 ± 0.082	4.948IleLys: 4.948 ± 0.073	6.227IleLeu: 6.227 ± 0.084	1.897IleMet: 1.897 ± 0.039	3.849IleAsn: 3.849 ± 0.058	3.235IlePro: 3.235 ± 0.06	2.027IleGln: 2.027 ± 0.043	3.279IleArg: 3.279 ± 0.049	4.48IleSer: 4.48 ± 0.071	4.387IleThr: 4.387 ± 0.058	4.476IleVal: 4.476 ± 0.064	0.613IleTrp: 0.613 ± 0.019	2.423IleTyr: 2.423 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.382LysAla: 4.382 ± 0.066	0.644LysCys: 0.644 ± 0.025	3.224LysAsp: 3.224 ± 0.055	4.725LysGlu: 4.725 ± 0.07	1.822LysPhe: 1.822 ± 0.039	3.705LysGly: 3.705 ± 0.049	1.139LysHis: 1.139 ± 0.033	4.534LysIle: 4.534 ± 0.065	4.302LysLys: 4.302 ± 0.065	5.532LysLeu: 5.532 ± 0.065	1.785LysMet: 1.785 ± 0.038	2.848LysAsn: 2.848 ± 0.052	2.399LysPro: 2.399 ± 0.05	2.274LysGln: 2.274 ± 0.048	2.765LysArg: 2.765 ± 0.049	2.916LysSer: 2.916 ± 0.048	3.193LysThr: 3.193 ± 0.053	4.243LysVal: 4.243 ± 0.065	0.556LysTrp: 0.556 ± 0.023	2.255LysTyr: 2.255 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	9.313LeuAla: 9.313 ± 0.092	1.212LeuCys: 1.212 ± 0.039	5.232LeuAsp: 5.232 ± 0.071	6.454LeuGlu: 6.454 ± 0.089	3.716LeuPhe: 3.716 ± 0.061	7.384LeuGly: 7.384 ± 0.079	1.888LeuHis: 1.888 ± 0.046	6.22LeuIle: 6.22 ± 0.078	5.772LeuLys: 5.772 ± 0.071	9.921LeuLeu: 9.921 ± 0.136	2.453LeuMet: 2.453 ± 0.047	4.277LeuAsn: 4.277 ± 0.055	4.611LeuPro: 4.611 ± 0.061	3.561LeuGln: 3.561 ± 0.057	4.908LeuArg: 4.908 ± 0.072	5.81LeuSer: 5.81 ± 0.063	5.311LeuThr: 5.311 ± 0.073	7.508LeuVal: 7.508 ± 0.087	0.947LeuTrp: 0.947 ± 0.032	2.931LeuTyr: 2.931 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.646MetAla: 2.646 ± 0.048	0.284MetCys: 0.284 ± 0.016	1.503MetAsp: 1.503 ± 0.033	1.94MetGlu: 1.94 ± 0.039	0.869MetPhe: 0.869 ± 0.028	2.106MetGly: 2.106 ± 0.041	0.53MetHis: 0.53 ± 0.021	1.648MetIle: 1.648 ± 0.035	1.541MetLys: 1.541 ± 0.038	2.802MetLeu: 2.802 ± 0.051	0.648MetMet: 0.648 ± 0.028	1.065MetAsn: 1.065 ± 0.027	1.327MetPro: 1.327 ± 0.034	1.175MetGln: 1.175 ± 0.03	1.387MetArg: 1.387 ± 0.03	1.548MetSer: 1.548 ± 0.034	1.376MetThr: 1.376 ± 0.033	2.129MetVal: 2.129 ± 0.043	0.181MetTrp: 0.181 ± 0.014	0.671MetTyr: 0.671 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.878AsnAla: 2.878 ± 0.045	0.641AsnCys: 0.641 ± 0.024	2.101AsnAsp: 2.101 ± 0.041	2.451AsnGlu: 2.451 ± 0.051	1.617AsnPhe: 1.617 ± 0.036	2.901AsnGly: 2.901 ± 0.051	0.782AsnHis: 0.782 ± 0.025	3.555AsnIle: 3.555 ± 0.053	2.736AsnLys: 2.736 ± 0.047	4.165AsnLeu: 4.165 ± 0.065	1.208AsnMet: 1.208 ± 0.03	2.184AsnAsn: 2.184 ± 0.04	2.204AsnPro: 2.204 ± 0.05	1.639AsnGln: 1.639 ± 0.04	2.356AsnArg: 2.356 ± 0.043	2.238AsnSer: 2.238 ± 0.042	2.201AsnThr: 2.201 ± 0.047	2.772AsnVal: 2.772 ± 0.052	0.523AsnTrp: 0.523 ± 0.019	1.597AsnTyr: 1.597 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.338ProAla: 3.338 ± 0.068	0.476ProCys: 0.476 ± 0.022	2.57ProAsp: 2.57 ± 0.05	3.49ProGlu: 3.49 ± 0.053	1.563ProPhe: 1.563 ± 0.035	4.107ProGly: 4.107 ± 0.069	0.821ProHis: 0.821 ± 0.025	2.134ProIle: 2.134 ± 0.043	1.828ProLys: 1.828 ± 0.042	3.882ProLeu: 3.882 ± 0.055	0.944ProMet: 0.944 ± 0.024	1.446ProAsn: 1.446 ± 0.037	1.774ProPro: 1.774 ± 0.039	1.508ProGln: 1.508 ± 0.032	2.065ProArg: 2.065 ± 0.038	1.927ProSer: 1.927 ± 0.038	1.881ProThr: 1.881 ± 0.042	4.108ProVal: 4.108 ± 0.06	0.445ProTrp: 0.445 ± 0.02	1.413ProTyr: 1.413 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.163GlnAla: 3.163 ± 0.054	0.444GlnCys: 0.444 ± 0.019	1.677GlnAsp: 1.677 ± 0.036	2.526GlnGlu: 2.526 ± 0.049	1.216GlnPhe: 1.216 ± 0.028	2.384GlnGly: 2.384 ± 0.048	0.616GlnHis: 0.616 ± 0.022	2.535GlnIle: 2.535 ± 0.049	2.374GlnLys: 2.374 ± 0.046	3.669GlnLeu: 3.669 ± 0.056	1.06GlnMet: 1.06 ± 0.027	1.593GlnAsn: 1.593 ± 0.035	1.354GlnPro: 1.354 ± 0.037	1.725GlnGln: 1.725 ± 0.056	1.936GlnArg: 1.936 ± 0.047	1.81GlnSer: 1.81 ± 0.042	1.773GlnThr: 1.773 ± 0.038	2.978GlnVal: 2.978 ± 0.052	0.427GlnTrp: 0.427 ± 0.021	1.255GlnTyr: 1.255 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	3.666ArgAla: 3.666 ± 0.066	0.678ArgCys: 0.678 ± 0.024	2.876ArgAsp: 2.876 ± 0.044	4.339ArgGlu: 4.339 ± 0.074	1.959ArgPhe: 1.959 ± 0.04	3.479ArgGly: 3.479 ± 0.056	1.102ArgHis: 1.102 ± 0.032	3.424ArgIle: 3.424 ± 0.049	3.011ArgLys: 3.011 ± 0.056	5.459ArgLeu: 5.459 ± 0.072	1.478ArgMet: 1.478 ± 0.034	1.994ArgAsn: 1.994 ± 0.04	2.003ArgPro: 2.003 ± 0.04	2.353ArgGln: 2.353 ± 0.047	3.147ArgArg: 3.147 ± 0.07	2.504ArgSer: 2.504 ± 0.039	2.35ArgThr: 2.35 ± 0.044	4.012ArgVal: 4.012 ± 0.064	0.637ArgTrp: 0.637 ± 0.024	1.947ArgTyr: 1.947 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	3.956SerAla: 3.956 ± 0.058	0.689SerCys: 0.689 ± 0.025	2.708SerAsp: 2.708 ± 0.039	3.049SerGlu: 3.049 ± 0.046	2.358SerPhe: 2.358 ± 0.046	4.836SerGly: 4.836 ± 0.066	0.975SerHis: 0.975 ± 0.028	3.774SerIle: 3.774 ± 0.059	2.836SerLys: 2.836 ± 0.049	5.323SerLeu: 5.323 ± 0.063	1.456SerMet: 1.456 ± 0.035	2.081SerAsn: 2.081 ± 0.039	2.371SerPro: 2.371 ± 0.041	1.853SerGln: 1.853 ± 0.037	2.878SerArg: 2.878 ± 0.055	3.052SerSer: 3.052 ± 0.047	2.791SerThr: 2.791 ± 0.048	3.594SerVal: 3.594 ± 0.054	0.573SerTrp: 0.573 ± 0.021	1.874SerTyr: 1.874 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	4.518ThrAla: 4.518 ± 0.074	0.619ThrCys: 0.619 ± 0.021	2.614ThrAsp: 2.614 ± 0.049	2.92ThrGlu: 2.92 ± 0.047	1.969ThrPhe: 1.969 ± 0.042	5.297ThrGly: 5.297 ± 0.068	0.916ThrHis: 0.916 ± 0.026	3.58ThrIle: 3.58 ± 0.058	2.395ThrLys: 2.395 ± 0.047	5.044ThrLeu: 5.044 ± 0.076	1.327ThrMet: 1.327 ± 0.035	1.963ThrAsn: 1.963 ± 0.038	2.484ThrPro: 2.484 ± 0.048	1.375ThrGln: 1.375 ± 0.035	2.483ThrArg: 2.483 ± 0.043	2.659ThrSer: 2.659 ± 0.05	2.683ThrThr: 2.683 ± 0.047	4.5ThrVal: 4.5 ± 0.076	0.54ThrTrp: 0.54 ± 0.022	1.585ThrTyr: 1.585 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	6.137ValAla: 6.137 ± 0.092	0.936ValCys: 0.936 ± 0.03	4.192ValAsp: 4.192 ± 0.064	4.885ValGlu: 4.885 ± 0.066	2.941ValPhe: 2.941 ± 0.053	5.067ValGly: 5.067 ± 0.075	1.405ValHis: 1.405 ± 0.036	5.332ValIle: 5.332 ± 0.073	4.136ValLys: 4.136 ± 0.058	7.659ValLeu: 7.659 ± 0.091	1.968ValMet: 1.968 ± 0.034	3.161ValAsn: 3.161 ± 0.053	3.273ValPro: 3.273 ± 0.053	2.536ValGln: 2.536 ± 0.05	3.711ValArg: 3.711 ± 0.052	4.056ValSer: 4.056 ± 0.058	4.143ValThr: 4.143 ± 0.065	5.828ValVal: 5.828 ± 0.087	0.661ValTrp: 0.661 ± 0.022	2.373ValTyr: 2.373 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.679TrpAla: 0.679 ± 0.024	0.14TrpCys: 0.14 ± 0.011	0.587TrpAsp: 0.587 ± 0.022	0.703TrpGlu: 0.703 ± 0.024	0.436TrpPhe: 0.436 ± 0.023	0.796TrpGly: 0.796 ± 0.03	0.228TrpHis: 0.228 ± 0.014	0.543TrpIle: 0.543 ± 0.022	0.518TrpLys: 0.518 ± 0.022	1.188TrpLeu: 1.188 ± 0.033	0.273TrpMet: 0.273 ± 0.013	0.434TrpAsn: 0.434 ± 0.018	0.404TrpPro: 0.404 ± 0.017	0.518TrpGln: 0.518 ± 0.02	0.562TrpArg: 0.562 ± 0.022	0.547TrpSer: 0.547 ± 0.022	0.427TrpThr: 0.427 ± 0.023	0.751TrpVal: 0.751 ± 0.024	0.155TrpTrp: 0.155 ± 0.009	0.345TrpTyr: 0.345 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.43TyrAla: 2.43 ± 0.043	0.512TyrCys: 0.512 ± 0.022	1.832TyrAsp: 1.832 ± 0.042	1.897TyrGlu: 1.897 ± 0.038	1.493TyrPhe: 1.493 ± 0.038	2.607TyrGly: 2.607 ± 0.051	0.757TyrHis: 0.757 ± 0.023	2.422TyrIle: 2.422 ± 0.042	1.822TyrLys: 1.822 ± 0.04	3.616TyrLeu: 3.616 ± 0.063	0.819TyrMet: 0.819 ± 0.024	1.568TyrAsn: 1.568 ± 0.038	1.533TyrPro: 1.533 ± 0.041	1.377TyrGln: 1.377 ± 0.037	2.152TyrArg: 2.152 ± 0.049	1.939TyrSer: 1.939 ± 0.041	1.853TyrThr: 1.853 ± 0.037	2.037TyrVal: 2.037 ± 0.038	0.426TyrTrp: 0.426 ± 0.022	1.462TyrTyr: 1.462 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4313 proteins (1287869 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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