Amino acid dipepetide frequency for Flavimobilis marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.119AlaAla: 22.119 ± 0.237	0.872AlaCys: 0.872 ± 0.035	8.904AlaAsp: 8.904 ± 0.129	8.32AlaGlu: 8.32 ± 0.109	3.542AlaPhe: 3.542 ± 0.061	13.432AlaGly: 13.432 ± 0.157	2.8AlaHis: 2.8 ± 0.057	4.634AlaIle: 4.634 ± 0.066	2.51AlaLys: 2.51 ± 0.07	15.265AlaLeu: 15.265 ± 0.166	2.857AlaMet: 2.857 ± 0.059	2.08AlaAsn: 2.08 ± 0.05	7.747AlaPro: 7.747 ± 0.126	4.403AlaGln: 4.403 ± 0.074	11.133AlaArg: 11.133 ± 0.171	7.225AlaSer: 7.225 ± 0.091	8.297AlaThr: 8.297 ± 0.126	12.814AlaVal: 12.814 ± 0.161	2.115AlaTrp: 2.115 ± 0.046	2.44AlaTyr: 2.44 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.801CysAla: 0.801 ± 0.031	0.053CysCys: 0.053 ± 0.008	0.335CysAsp: 0.335 ± 0.018	0.33CysGlu: 0.33 ± 0.02	0.148CysPhe: 0.148 ± 0.015	0.632CysGly: 0.632 ± 0.031	0.115CysHis: 0.115 ± 0.012	0.143CysIle: 0.143 ± 0.014	0.077CysLys: 0.077 ± 0.009	0.512CysLeu: 0.512 ± 0.023	0.073CysMet: 0.073 ± 0.01	0.102CysAsn: 0.102 ± 0.011	0.358CysPro: 0.358 ± 0.022	0.141CysGln: 0.141 ± 0.012	0.371CysArg: 0.371 ± 0.02	0.369CysSer: 0.369 ± 0.021	0.348CysThr: 0.348 ± 0.02	0.485CysVal: 0.485 ± 0.022	0.091CysTrp: 0.091 ± 0.009	0.119CysTyr: 0.119 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	9.65AspAla: 9.65 ± 0.116	0.272AspCys: 0.272 ± 0.017	4.77AspAsp: 4.77 ± 0.086	4.167AspGlu: 4.167 ± 0.075	1.418AspPhe: 1.418 ± 0.04	6.536AspGly: 6.536 ± 0.107	1.289AspHis: 1.289 ± 0.042	1.725AspIle: 1.725 ± 0.044	0.917AspLys: 0.917 ± 0.039	6.9AspLeu: 6.9 ± 0.103	0.841AspMet: 0.841 ± 0.031	0.807AspAsn: 0.807 ± 0.034	4.242AspPro: 4.242 ± 0.082	1.638AspGln: 1.638 ± 0.047	4.175AspArg: 4.175 ± 0.069	2.169AspSer: 2.169 ± 0.056	2.711AspThr: 2.711 ± 0.064	7.049AspVal: 7.049 ± 0.096	0.818AspTrp: 0.818 ± 0.03	1.09AspTyr: 1.09 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.509GluAla: 7.509 ± 0.109	0.271GluCys: 0.271 ± 0.019	3.029GluAsp: 3.029 ± 0.063	2.882GluGlu: 2.882 ± 0.071	1.352GluPhe: 1.352 ± 0.042	4.14GluGly: 4.14 ± 0.074	1.732GluHis: 1.732 ± 0.048	2.584GluIle: 2.584 ± 0.054	1.057GluLys: 1.057 ± 0.041	6.447GluLeu: 6.447 ± 0.113	0.97GluMet: 0.97 ± 0.039	0.959GluAsn: 0.959 ± 0.032	3.53GluPro: 3.53 ± 0.07	2.206GluGln: 2.206 ± 0.057	5.384GluArg: 5.384 ± 0.094	2.524GluSer: 2.524 ± 0.058	2.887GluThr: 2.887 ± 0.059	5.353GluVal: 5.353 ± 0.078	0.654GluTrp: 0.654 ± 0.026	0.996GluTyr: 0.996 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.677PheAla: 3.677 ± 0.068	0.206PheCys: 0.206 ± 0.015	1.882PheAsp: 1.882 ± 0.054	1.494PheGlu: 1.494 ± 0.046	0.877PhePhe: 0.877 ± 0.037	2.734PheGly: 2.734 ± 0.063	0.492PheHis: 0.492 ± 0.027	0.763PheIle: 0.763 ± 0.037	0.429PheLys: 0.429 ± 0.021	2.443PheLeu: 2.443 ± 0.059	0.407PheMet: 0.407 ± 0.02	0.513PheAsn: 0.513 ± 0.025	1.202PhePro: 1.202 ± 0.042	0.606PheGln: 0.606 ± 0.024	1.625PheArg: 1.625 ± 0.046	1.494PheSer: 1.494 ± 0.045	1.845PheThr: 1.845 ± 0.05	2.616PheVal: 2.616 ± 0.06	0.417PheTrp: 0.417 ± 0.023	0.577PheTyr: 0.577 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	12.249GlyAla: 12.249 ± 0.172	0.569GlyCys: 0.569 ± 0.027	5.134GlyAsp: 5.134 ± 0.089	4.95GlyGlu: 4.95 ± 0.074	2.674GlyPhe: 2.674 ± 0.056	7.689GlyGly: 7.689 ± 0.134	1.932GlyHis: 1.932 ± 0.048	3.532GlyIle: 3.532 ± 0.061	2.202GlyLys: 2.202 ± 0.066	9.048GlyLeu: 9.048 ± 0.105	1.924GlyMet: 1.924 ± 0.046	1.427GlyAsn: 1.427 ± 0.044	4.563GlyPro: 4.563 ± 0.076	2.588GlyGln: 2.588 ± 0.056	6.81GlyArg: 6.81 ± 0.102	5.186GlySer: 5.186 ± 0.087	6.07GlyThr: 6.07 ± 0.098	8.336GlyVal: 8.336 ± 0.113	1.592GlyTrp: 1.592 ± 0.05	2.141GlyTyr: 2.141 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	2.79HisAla: 2.79 ± 0.064	0.129HisCys: 0.129 ± 0.011	1.428HisAsp: 1.428 ± 0.044	1.295HisGlu: 1.295 ± 0.042	0.486HisPhe: 0.486 ± 0.022	2.112HisGly: 2.112 ± 0.051	0.545HisHis: 0.545 ± 0.023	0.5HisIle: 0.5 ± 0.028	0.282HisLys: 0.282 ± 0.021	2.366HisLeu: 2.366 ± 0.059	0.295HisMet: 0.295 ± 0.018	0.333HisAsn: 0.333 ± 0.02	1.476HisPro: 1.476 ± 0.046	0.537HisGln: 0.537 ± 0.023	1.561HisArg: 1.561 ± 0.044	0.787HisSer: 0.787 ± 0.032	1.041HisThr: 1.041 ± 0.035	2.084HisVal: 2.084 ± 0.056	0.259HisTrp: 0.259 ± 0.015	0.394HisTyr: 0.394 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.306IleAla: 5.306 ± 0.089	0.219IleCys: 0.219 ± 0.016	2.724IleAsp: 2.724 ± 0.057	2.312IleGlu: 2.312 ± 0.054	0.855IlePhe: 0.855 ± 0.033	3.377IleGly: 3.377 ± 0.076	0.536IleHis: 0.536 ± 0.026	1.127IleIle: 1.127 ± 0.045	0.779IleLys: 0.779 ± 0.033	2.731IleLeu: 2.731 ± 0.063	0.491IleMet: 0.491 ± 0.025	0.735IleAsn: 0.735 ± 0.035	1.783IlePro: 1.783 ± 0.043	0.723IleGln: 0.723 ± 0.026	1.998IleArg: 1.998 ± 0.05	1.748IleSer: 1.748 ± 0.045	2.294IleThr: 2.294 ± 0.056	3.51IleVal: 3.51 ± 0.066	0.35IleTrp: 0.35 ± 0.022	0.575IleTyr: 0.575 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.227LysAla: 2.227 ± 0.063	0.075LysCys: 0.075 ± 0.01	1.088LysAsp: 1.088 ± 0.04	0.878LysGlu: 0.878 ± 0.038	0.438LysPhe: 0.438 ± 0.024	1.434LysGly: 1.434 ± 0.045	0.429LysHis: 0.429 ± 0.022	0.936LysIle: 0.936 ± 0.036	0.792LysLys: 0.792 ± 0.044	1.512LysLeu: 1.512 ± 0.052	0.32LysMet: 0.32 ± 0.018	0.458LysAsn: 0.458 ± 0.025	1.055LysPro: 1.055 ± 0.04	0.534LysGln: 0.534 ± 0.025	1.315LysArg: 1.315 ± 0.044	0.984LysSer: 0.984 ± 0.036	1.118LysThr: 1.118 ± 0.043	1.852LysVal: 1.852 ± 0.057	0.159LysTrp: 0.159 ± 0.013	0.391LysTyr: 0.391 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	16.438LeuAla: 16.438 ± 0.182	0.539LeuCys: 0.539 ± 0.025	7.14LeuAsp: 7.14 ± 0.111	5.539LeuGlu: 5.539 ± 0.097	2.351LeuPhe: 2.351 ± 0.053	9.718LeuGly: 9.718 ± 0.112	1.811LeuHis: 1.811 ± 0.05	2.958LeuIle: 2.958 ± 0.068	1.492LeuLys: 1.492 ± 0.049	10.24LeuLeu: 10.24 ± 0.149	1.568LeuMet: 1.568 ± 0.041	1.479LeuAsn: 1.479 ± 0.044	5.598LeuPro: 5.598 ± 0.077	2.19LeuGln: 2.19 ± 0.048	8.004LeuArg: 8.004 ± 0.106	4.877LeuSer: 4.877 ± 0.077	6.769LeuThr: 6.769 ± 0.094	10.756LeuVal: 10.756 ± 0.142	1.211LeuTrp: 1.211 ± 0.037	1.396LeuTyr: 1.396 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.326MetAla: 2.326 ± 0.057	0.108MetCys: 0.108 ± 0.012	0.886MetAsp: 0.886 ± 0.03	0.607MetGlu: 0.607 ± 0.028	0.509MetPhe: 0.509 ± 0.027	1.268MetGly: 1.268 ± 0.04	0.356MetHis: 0.356 ± 0.021	0.775MetIle: 0.775 ± 0.032	0.338MetLys: 0.338 ± 0.019	1.764MetLeu: 1.764 ± 0.041	0.282MetMet: 0.282 ± 0.019	0.424MetAsn: 0.424 ± 0.023	1.015MetPro: 1.015 ± 0.032	0.38MetGln: 0.38 ± 0.021	1.367MetArg: 1.367 ± 0.036	1.419MetSer: 1.419 ± 0.041	1.763MetThr: 1.763 ± 0.04	1.44MetVal: 1.44 ± 0.041	0.199MetTrp: 0.199 ± 0.016	0.267MetTyr: 0.267 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.123AsnAla: 2.123 ± 0.045	0.102AsnCys: 0.102 ± 0.01	1.011AsnAsp: 1.011 ± 0.036	0.852AsnGlu: 0.852 ± 0.032	0.451AsnPhe: 0.451 ± 0.025	1.405AsnGly: 1.405 ± 0.039	0.379AsnHis: 0.379 ± 0.023	0.66AsnIle: 0.66 ± 0.028	0.343AsnLys: 0.343 ± 0.02	1.744AsnLeu: 1.744 ± 0.047	0.301AsnMet: 0.301 ± 0.023	0.371AsnAsn: 0.371 ± 0.023	1.306AsnPro: 1.306 ± 0.041	0.499AsnGln: 0.499 ± 0.027	1.068AsnArg: 1.068 ± 0.038	0.671AsnSer: 0.671 ± 0.03	0.831AsnThr: 0.831 ± 0.035	1.511AsnVal: 1.511 ± 0.04	0.201AsnTrp: 0.201 ± 0.015	0.395AsnTyr: 0.395 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	8.429ProAla: 8.429 ± 0.131	0.206ProCys: 0.206 ± 0.017	4.433ProAsp: 4.433 ± 0.085	4.003ProGlu: 4.003 ± 0.087	1.496ProPhe: 1.496 ± 0.044	5.692ProGly: 5.692 ± 0.097	1.175ProHis: 1.175 ± 0.036	1.457ProIle: 1.457 ± 0.041	0.852ProLys: 0.852 ± 0.038	4.778ProLeu: 4.778 ± 0.079	0.901ProMet: 0.901 ± 0.03	0.742ProAsn: 0.742 ± 0.028	2.551ProPro: 2.551 ± 0.064	1.436ProGln: 1.436 ± 0.042	3.638ProArg: 3.638 ± 0.071	3.128ProSer: 3.128 ± 0.062	3.979ProThr: 3.979 ± 0.08	5.453ProVal: 5.453 ± 0.089	0.881ProTrp: 0.881 ± 0.031	1.045ProTyr: 1.045 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.67GlnAla: 3.67 ± 0.077	0.117GlnCys: 0.117 ± 0.012	1.358GlnAsp: 1.358 ± 0.039	1.405GlnGlu: 1.405 ± 0.044	0.665GlnPhe: 0.665 ± 0.026	2.103GlnGly: 2.103 ± 0.057	0.674GlnHis: 0.674 ± 0.029	1.273GlnIle: 1.273 ± 0.035	0.42GlnLys: 0.42 ± 0.022	2.935GlnLeu: 2.935 ± 0.064	0.562GlnMet: 0.562 ± 0.022	0.472GlnAsn: 0.472 ± 0.027	1.503GlnPro: 1.503 ± 0.047	0.954GlnGln: 0.954 ± 0.041	2.398GlnArg: 2.398 ± 0.059	1.144GlnSer: 1.144 ± 0.036	1.613GlnThr: 1.613 ± 0.046	2.923GlnVal: 2.923 ± 0.057	0.418GlnTrp: 0.418 ± 0.025	0.532GlnTyr: 0.532 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	10.474ArgAla: 10.474 ± 0.146	0.432ArgCys: 0.432 ± 0.025	4.322ArgAsp: 4.322 ± 0.074	4.558ArgGlu: 4.558 ± 0.078	2.08ArgPhe: 2.08 ± 0.053	5.864ArgGly: 5.864 ± 0.093	1.588ArgHis: 1.588 ± 0.041	2.601ArgIle: 2.601 ± 0.062	1.338ArgLys: 1.338 ± 0.048	7.764ArgLeu: 7.764 ± 0.101	1.61ArgMet: 1.61 ± 0.039	1.137ArgAsn: 1.137 ± 0.039	4.197ArgPro: 4.197 ± 0.075	2.024ArgGln: 2.024 ± 0.056	7.046ArgArg: 7.046 ± 0.126	4.166ArgSer: 4.166 ± 0.071	5.121ArgThr: 5.121 ± 0.073	6.581ArgVal: 6.581 ± 0.092	1.353ArgTrp: 1.353 ± 0.037	1.637ArgTyr: 1.637 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	7.153SerAla: 7.153 ± 0.099	0.291SerCys: 0.291 ± 0.023	2.906SerAsp: 2.906 ± 0.063	2.588SerGlu: 2.588 ± 0.048	1.538SerPhe: 1.538 ± 0.044	5.479SerGly: 5.479 ± 0.089	0.909SerHis: 0.909 ± 0.027	1.875SerIle: 1.875 ± 0.048	0.911SerLys: 0.911 ± 0.038	4.912SerLeu: 4.912 ± 0.073	1.057SerMet: 1.057 ± 0.036	0.836SerAsn: 0.836 ± 0.033	2.936SerPro: 2.936 ± 0.063	1.358SerGln: 1.358 ± 0.04	3.598SerArg: 3.598 ± 0.062	3.065SerSer: 3.065 ± 0.069	3.494SerThr: 3.494 ± 0.073	4.553SerVal: 4.553 ± 0.08	0.884SerTrp: 0.884 ± 0.034	1.099SerTyr: 1.099 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	8.278ThrAla: 8.278 ± 0.109	0.342ThrCys: 0.342 ± 0.021	3.719ThrAsp: 3.719 ± 0.051	3.16ThrGlu: 3.16 ± 0.077	1.943ThrPhe: 1.943 ± 0.051	6.018ThrGly: 6.018 ± 0.108	1.168ThrHis: 1.168 ± 0.038	2.439ThrIle: 2.439 ± 0.058	1.178ThrLys: 1.178 ± 0.048	6.175ThrLeu: 6.175 ± 0.094	1.041ThrMet: 1.041 ± 0.034	1.085ThrAsn: 1.085 ± 0.036	4.093ThrPro: 4.093 ± 0.08	1.551ThrGln: 1.551 ± 0.04	3.946ThrArg: 3.946 ± 0.06	3.854ThrSer: 3.854 ± 0.063	4.699ThrThr: 4.699 ± 0.084	6.166ThrVal: 6.166 ± 0.112	1.031ThrTrp: 1.031 ± 0.037	1.351ThrTyr: 1.351 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	14.144ValAla: 14.144 ± 0.167	0.572ValCys: 0.572 ± 0.024	6.044ValAsp: 6.044 ± 0.095	5.376ValGlu: 5.376 ± 0.083	2.376ValPhe: 2.376 ± 0.057	8.154ValGly: 8.154 ± 0.118	2.048ValHis: 2.048 ± 0.051	3.255ValIle: 3.255 ± 0.071	1.519ValLys: 1.519 ± 0.055	10.764ValLeu: 10.764 ± 0.126	1.494ValMet: 1.494 ± 0.042	1.575ValAsn: 1.575 ± 0.045	5.436ValPro: 5.436 ± 0.078	2.328ValGln: 2.328 ± 0.051	7.578ValArg: 7.578 ± 0.109	4.785ValSer: 4.785 ± 0.07	6.354ValThr: 6.354 ± 0.101	12.048ValVal: 12.048 ± 0.154	1.19ValTrp: 1.19 ± 0.039	1.511ValTyr: 1.511 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.626TrpAla: 1.626 ± 0.052	0.107TrpCys: 0.107 ± 0.01	0.843TrpAsp: 0.843 ± 0.032	0.669TrpGlu: 0.669 ± 0.027	0.499TrpPhe: 0.499 ± 0.026	1.005TrpGly: 1.005 ± 0.035	0.384TrpHis: 0.384 ± 0.02	0.487TrpIle: 0.487 ± 0.025	0.259TrpLys: 0.259 ± 0.019	1.639TrpLeu: 1.639 ± 0.05	0.277TrpMet: 0.277 ± 0.019	0.358TrpAsn: 0.358 ± 0.019	0.744TrpPro: 0.744 ± 0.029	0.519TrpGln: 0.519 ± 0.024	1.338TrpArg: 1.338 ± 0.044	0.898TrpSer: 0.898 ± 0.035	0.988TrpThr: 0.988 ± 0.032	1.191TrpVal: 1.191 ± 0.038	0.354TrpTrp: 0.354 ± 0.021	0.267TrpTyr: 0.267 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.52TyrAla: 2.52 ± 0.056	0.12TyrCys: 0.12 ± 0.012	1.23TyrAsp: 1.23 ± 0.042	1.081TyrGlu: 1.081 ± 0.037	0.599TyrPhe: 0.599 ± 0.03	1.824TyrGly: 1.824 ± 0.054	0.337TyrHis: 0.337 ± 0.02	0.449TyrIle: 0.449 ± 0.023	0.3TyrLys: 0.3 ± 0.019	2.138TyrLeu: 2.138 ± 0.054	0.221TyrMet: 0.221 ± 0.016	0.329TyrAsn: 0.329 ± 0.018	0.94TyrPro: 0.94 ± 0.034	0.527TyrGln: 0.527 ± 0.026	1.54TyrArg: 1.54 ± 0.043	0.951TyrSer: 0.951 ± 0.036	1.013TyrThr: 1.013 ± 0.037	1.83TyrVal: 1.83 ± 0.05	0.274TyrTrp: 0.274 ± 0.017	0.453TyrTyr: 0.453 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2643 proteins (894391 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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