Amino acid dipepetide frequency for Bark beetle-associated genomovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.587AlaAla: 1.587 ± 1.124
1.587AlaCys: 1.587 ± 1.099
6.349AlaAsp: 6.349 ± 4.396
4.762AlaGlu: 4.762 ± 1.074
0.0AlaPhe: 0.0 ± 0.0
9.524AlaGly: 9.524 ± 0.074
0.0AlaHis: 0.0 ± 0.0
4.762AlaIle: 4.762 ± 1.074
4.762AlaLys: 4.762 ± 1.148
3.175AlaLeu: 3.175 ± 2.198
1.587AlaMet: 1.587 ± 1.124
6.349AlaAsn: 6.349 ± 2.173
1.587AlaPro: 1.587 ± 1.124
0.0AlaGln: 0.0 ± 0.0
7.937AlaArg: 7.937 ± 3.272
6.349AlaSer: 6.349 ± 2.272
6.349AlaThr: 6.349 ± 2.272
6.349AlaVal: 6.349 ± 0.049
0.0AlaTrp: 0.0 ± 0.0
1.587AlaTyr: 1.587 ± 1.124
0.0AlaXaa: 0.0 ± 0.0
Cys
1.587CysAla: 1.587 ± 1.099
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.587CysGlu: 1.587 ± 1.099
3.175CysPhe: 3.175 ± 2.247
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.587CysIle: 1.587 ± 1.099
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.587CysMet: 1.587 ± 1.124
1.587CysAsn: 1.587 ± 1.099
0.0CysPro: 0.0 ± 0.0
1.587CysGln: 1.587 ± 1.099
0.0CysArg: 0.0 ± 0.0
1.587CysSer: 1.587 ± 1.099
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.587CysTyr: 1.587 ± 1.124
0.0CysXaa: 0.0 ± 0.0
Asp
1.587AspAla: 1.587 ± 1.099
0.0AspCys: 0.0 ± 0.0
7.937AspAsp: 7.937 ± 1.05
3.175AspGlu: 3.175 ± 0.025
3.175AspPhe: 3.175 ± 0.025
3.175AspGly: 3.175 ± 2.198
1.587AspHis: 1.587 ± 1.099
6.349AspIle: 6.349 ± 2.173
1.587AspLys: 1.587 ± 1.124
6.349AspLeu: 6.349 ± 0.049
1.587AspMet: 1.587 ± 1.099
1.587AspAsn: 1.587 ± 1.099
4.762AspPro: 4.762 ± 3.297
0.0AspGln: 0.0 ± 0.0
3.175AspArg: 3.175 ± 2.198
1.587AspSer: 1.587 ± 1.124
6.349AspThr: 6.349 ± 2.272
4.762AspVal: 4.762 ± 1.074
4.762AspTrp: 4.762 ± 1.074
3.175AspTyr: 3.175 ± 2.198
0.0AspXaa: 0.0 ± 0.0
Glu
3.175GluAla: 3.175 ± 2.198
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
1.587GluGlu: 1.587 ± 1.099
3.175GluPhe: 3.175 ± 2.198
1.587GluGly: 1.587 ± 1.099
0.0GluHis: 0.0 ± 0.0
3.175GluIle: 3.175 ± 2.198
1.587GluLys: 1.587 ± 1.124
3.175GluLeu: 3.175 ± 2.198
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
3.175GluPro: 3.175 ± 2.198
1.587GluGln: 1.587 ± 1.099
4.762GluArg: 4.762 ± 1.148
4.762GluSer: 4.762 ± 1.148
4.762GluThr: 4.762 ± 1.148
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
12.698PheAla: 12.698 ± 6.569
3.175PheCys: 3.175 ± 0.025
6.349PheAsp: 6.349 ± 2.173
0.0PheGlu: 0.0 ± 0.0
3.175PhePhe: 3.175 ± 0.025
6.349PheGly: 6.349 ± 4.396
4.762PheHis: 4.762 ± 1.074
1.587PheIle: 1.587 ± 1.124
3.175PheLys: 3.175 ± 0.025
4.762PheLeu: 4.762 ± 1.074
1.587PheMet: 1.587 ± 1.099
0.0PheAsn: 0.0 ± 0.0
1.587PhePro: 1.587 ± 1.099
0.0PheGln: 0.0 ± 0.0
7.937PheArg: 7.937 ± 1.05
4.762PheSer: 4.762 ± 1.148
0.0PheThr: 0.0 ± 0.0
1.587PheVal: 1.587 ± 1.099
0.0PheTrp: 0.0 ± 0.0
1.587PheTyr: 1.587 ± 1.124
0.0PheXaa: 0.0 ± 0.0
Gly
6.349GlyAla: 6.349 ± 2.272
1.587GlyCys: 1.587 ± 1.099
6.349GlyAsp: 6.349 ± 2.173
1.587GlyGlu: 1.587 ± 1.124
4.762GlyPhe: 4.762 ± 1.148
9.524GlyGly: 9.524 ± 0.074
1.587GlyHis: 1.587 ± 1.099
3.175GlyIle: 3.175 ± 2.198
3.175GlyLys: 3.175 ± 2.198
3.175GlyLeu: 3.175 ± 0.025
6.349GlyMet: 6.349 ± 4.495
3.175GlyAsn: 3.175 ± 2.247
1.587GlyPro: 1.587 ± 1.099
3.175GlyGln: 3.175 ± 0.025
9.524GlyArg: 9.524 ± 4.371
3.175GlySer: 3.175 ± 2.247
6.349GlyThr: 6.349 ± 2.272
6.349GlyVal: 6.349 ± 2.173
0.0GlyTrp: 0.0 ± 0.0
3.175GlyTyr: 3.175 ± 2.198
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
3.175HisAsp: 3.175 ± 2.198
1.587HisGlu: 1.587 ± 1.124
3.175HisPhe: 3.175 ± 2.198
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.175HisLeu: 3.175 ± 2.198
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.175HisPro: 3.175 ± 0.025
0.0HisGln: 0.0 ± 0.0
1.587HisArg: 1.587 ± 1.124
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
4.762HisVal: 4.762 ± 1.074
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.349IleAla: 6.349 ± 0.049
1.587IleCys: 1.587 ± 1.124
0.0IleAsp: 0.0 ± 0.0
0.0IleGlu: 0.0 ± 0.0
6.349IlePhe: 6.349 ± 4.396
1.587IleGly: 1.587 ± 1.099
0.0IleHis: 0.0 ± 0.0
3.175IleIle: 3.175 ± 0.025
6.349IleLys: 6.349 ± 0.049
3.175IleLeu: 3.175 ± 2.198
0.0IleMet: 0.0 ± 0.0
3.175IleAsn: 3.175 ± 2.247
0.0IlePro: 0.0 ± 0.0
4.762IleGln: 4.762 ± 1.148
1.587IleArg: 1.587 ± 1.099
6.349IleSer: 6.349 ± 0.049
1.587IleThr: 1.587 ± 1.124
4.762IleVal: 4.762 ± 1.074
3.175IleTrp: 3.175 ± 0.025
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.175LysAla: 3.175 ± 2.247
0.0LysCys: 0.0 ± 0.0
3.175LysAsp: 3.175 ± 2.198
1.587LysGlu: 1.587 ± 1.099
7.937LysPhe: 7.937 ± 1.05
1.587LysGly: 1.587 ± 1.124
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
3.175LysLys: 3.175 ± 2.247
3.175LysLeu: 3.175 ± 0.025
1.587LysMet: 1.587 ± 0.797
1.587LysAsn: 1.587 ± 1.124
0.0LysPro: 0.0 ± 0.0
1.587LysGln: 1.587 ± 1.124
6.349LysArg: 6.349 ± 4.495
4.762LysSer: 4.762 ± 1.148
3.175LysThr: 3.175 ± 0.025
0.0LysVal: 0.0 ± 0.0
1.587LysTrp: 1.587 ± 1.099
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
3.175LeuAla: 3.175 ± 2.198
1.587LeuCys: 1.587 ± 1.099
4.762LeuAsp: 4.762 ± 3.297
3.175LeuGlu: 3.175 ± 2.198
6.349LeuPhe: 6.349 ± 0.049
9.524LeuGly: 9.524 ± 4.371
0.0LeuHis: 0.0 ± 0.0
6.349LeuIle: 6.349 ± 2.272
1.587LeuLys: 1.587 ± 1.124
0.0LeuLeu: 0.0 ± 0.0
0.0LeuMet: 0.0 ± 0.0
4.762LeuAsn: 4.762 ± 3.371
0.0LeuPro: 0.0 ± 0.0
0.0LeuGln: 0.0 ± 0.0
1.587LeuArg: 1.587 ± 1.124
1.587LeuSer: 1.587 ± 1.124
0.0LeuThr: 0.0 ± 0.0
6.349LeuVal: 6.349 ± 2.173
4.762LeuTrp: 4.762 ± 1.148
3.175LeuTyr: 3.175 ± 2.198
0.0LeuXaa: 0.0 ± 0.0
Met
3.175MetAla: 3.175 ± 2.247
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
3.175MetGlu: 3.175 ± 0.025
0.0MetPhe: 0.0 ± 0.0
4.762MetGly: 4.762 ± 1.148
0.0MetHis: 0.0 ± 0.0
1.587MetIle: 1.587 ± 1.124
0.0MetLys: 0.0 ± 0.0
1.587MetLeu: 1.587 ± 1.124
0.0MetMet: 0.0 ± 0.0
3.175MetAsn: 3.175 ± 2.247
1.587MetPro: 1.587 ± 1.099
0.0MetGln: 0.0 ± 0.0
1.587MetArg: 1.587 ± 1.124
1.587MetSer: 1.587 ± 1.124
1.587MetThr: 1.587 ± 1.099
1.587MetVal: 1.587 ± 1.099
0.0MetTrp: 0.0 ± 0.0
1.587MetTyr: 1.587 ± 1.124
0.0MetXaa: 0.0 ± 0.0
Asn
4.762AsnAla: 4.762 ± 1.074
1.587AsnCys: 1.587 ± 1.099
1.587AsnAsp: 1.587 ± 1.124
1.587AsnGlu: 1.587 ± 1.124
1.587AsnPhe: 1.587 ± 1.099
3.175AsnGly: 3.175 ± 2.247
0.0AsnHis: 0.0 ± 0.0
3.175AsnIle: 3.175 ± 2.198
1.587AsnLys: 1.587 ± 1.124
3.175AsnLeu: 3.175 ± 2.247
1.587AsnMet: 1.587 ± 1.124
0.0AsnAsn: 0.0 ± 0.0
3.175AsnPro: 3.175 ± 2.247
4.762AsnGln: 4.762 ± 3.371
0.0AsnArg: 0.0 ± 0.0
9.524AsnSer: 9.524 ± 4.519
4.762AsnThr: 4.762 ± 1.074
1.587AsnVal: 1.587 ± 1.124
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.587ProAla: 1.587 ± 1.099
0.0ProCys: 0.0 ± 0.0
1.587ProAsp: 1.587 ± 1.099
3.175ProGlu: 3.175 ± 2.198
4.762ProPhe: 4.762 ± 1.074
3.175ProGly: 3.175 ± 2.247
1.587ProHis: 1.587 ± 1.099
1.587ProIle: 1.587 ± 1.099
0.0ProLys: 0.0 ± 0.0
0.0ProLeu: 0.0 ± 0.0
1.587ProMet: 1.587 ± 1.124
3.175ProAsn: 3.175 ± 0.025
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
3.175ProArg: 3.175 ± 2.198
4.762ProSer: 4.762 ± 3.297
4.762ProThr: 4.762 ± 3.371
1.587ProVal: 1.587 ± 1.124
1.587ProTrp: 1.587 ± 1.124
3.175ProTyr: 3.175 ± 0.025
0.0ProXaa: 0.0 ± 0.0
Gln
4.762GlnAla: 4.762 ± 1.148
0.0GlnCys: 0.0 ± 0.0
1.587GlnAsp: 1.587 ± 1.124
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
3.175GlnGly: 3.175 ± 2.247
0.0GlnHis: 0.0 ± 0.0
1.587GlnIle: 1.587 ± 1.099
1.587GlnLys: 1.587 ± 1.099
0.0GlnLeu: 0.0 ± 0.0
1.587GlnMet: 1.587 ± 1.099
1.587GlnAsn: 1.587 ± 1.124
0.0GlnPro: 0.0 ± 0.0
1.587GlnGln: 1.587 ± 1.124
1.587GlnArg: 1.587 ± 1.124
1.587GlnSer: 1.587 ± 1.124
3.175GlnThr: 3.175 ± 2.247
1.587GlnVal: 1.587 ± 1.124
0.0GlnTrp: 0.0 ± 0.0
3.175GlnTyr: 3.175 ± 0.025
0.0GlnXaa: 0.0 ± 0.0
Arg
1.587ArgAla: 1.587 ± 1.099
0.0ArgCys: 0.0 ± 0.0
4.762ArgAsp: 4.762 ± 3.297
1.587ArgGlu: 1.587 ± 1.099
4.762ArgPhe: 4.762 ± 3.297
6.349ArgGly: 6.349 ± 2.272
3.175ArgHis: 3.175 ± 2.198
4.762ArgIle: 4.762 ± 1.148
7.937ArgLys: 7.937 ± 3.396
4.762ArgLeu: 4.762 ± 1.148
1.587ArgMet: 1.587 ± 1.099
3.175ArgAsn: 3.175 ± 0.025
3.175ArgPro: 3.175 ± 2.198
1.587ArgGln: 1.587 ± 1.099
7.937ArgArg: 7.937 ± 3.396
7.937ArgSer: 7.937 ± 1.05
4.762ArgThr: 4.762 ± 1.148
1.587ArgVal: 1.587 ± 1.124
1.587ArgTrp: 1.587 ± 1.099
3.175ArgTyr: 3.175 ± 0.025
0.0ArgXaa: 0.0 ± 0.0
Ser
4.762SerAla: 4.762 ± 1.148
0.0SerCys: 0.0 ± 0.0
3.175SerAsp: 3.175 ± 0.025
1.587SerGlu: 1.587 ± 1.124
1.587SerPhe: 1.587 ± 1.099
6.349SerGly: 6.349 ± 0.049
1.587SerHis: 1.587 ± 1.124
3.175SerIle: 3.175 ± 2.247
4.762SerLys: 4.762 ± 1.148
6.349SerLeu: 6.349 ± 4.396
1.587SerMet: 1.587 ± 1.124
4.762SerAsn: 4.762 ± 3.371
9.524SerPro: 9.524 ± 0.074
3.175SerGln: 3.175 ± 2.247
6.349SerArg: 6.349 ± 2.173
4.762SerSer: 4.762 ± 1.148
3.175SerThr: 3.175 ± 2.247
4.762SerVal: 4.762 ± 3.371
1.587SerTrp: 1.587 ± 1.124
3.175SerTyr: 3.175 ± 2.247
0.0SerXaa: 0.0 ± 0.0
Thr
3.175ThrAla: 3.175 ± 2.247
3.175ThrCys: 3.175 ± 2.247
3.175ThrAsp: 3.175 ± 0.025
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
4.762ThrGly: 4.762 ± 1.148
1.587ThrHis: 1.587 ± 1.099
4.762ThrIle: 4.762 ± 1.148
0.0ThrLys: 0.0 ± 0.0
3.175ThrLeu: 3.175 ± 0.025
1.587ThrMet: 1.587 ± 0.804
3.175ThrAsn: 3.175 ± 2.247
6.349ThrPro: 6.349 ± 2.272
1.587ThrGln: 1.587 ± 1.124
3.175ThrArg: 3.175 ± 0.025
4.762ThrSer: 4.762 ± 3.371
4.762ThrThr: 4.762 ± 1.148
1.587ThrVal: 1.587 ± 1.099
1.587ThrTrp: 1.587 ± 1.124
4.762ThrTyr: 4.762 ± 1.148
0.0ThrXaa: 0.0 ± 0.0
Val
4.762ValAla: 4.762 ± 1.074
1.587ValCys: 1.587 ± 1.099
7.937ValAsp: 7.937 ± 3.396
6.349ValGlu: 6.349 ± 4.396
4.762ValPhe: 4.762 ± 3.297
1.587ValGly: 1.587 ± 1.124
1.587ValHis: 1.587 ± 1.099
1.587ValIle: 1.587 ± 1.124
1.587ValLys: 1.587 ± 1.099
3.175ValLeu: 3.175 ± 2.247
0.0ValMet: 0.0 ± 0.0
1.587ValAsn: 1.587 ± 1.124
1.587ValPro: 1.587 ± 1.124
3.175ValGln: 3.175 ± 2.247
0.0ValArg: 0.0 ± 0.0
3.175ValSer: 3.175 ± 2.198
3.175ValThr: 3.175 ± 0.025
6.349ValVal: 6.349 ± 0.049
3.175ValTrp: 3.175 ± 2.198
3.175ValTyr: 3.175 ± 2.247
0.0ValXaa: 0.0 ± 0.0
Trp
1.587TrpAla: 1.587 ± 1.099
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.587TrpPhe: 1.587 ± 1.124
4.762TrpGly: 4.762 ± 1.074
3.175TrpHis: 3.175 ± 2.247
1.587TrpIle: 1.587 ± 1.099
0.0TrpLys: 0.0 ± 0.0
6.349TrpLeu: 6.349 ± 0.049
0.0TrpMet: 0.0 ± 0.0
3.175TrpAsn: 3.175 ± 0.025
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
3.175TrpArg: 3.175 ± 2.198
1.587TrpSer: 1.587 ± 1.124
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.762TyrAla: 4.762 ± 1.148
0.0TyrCys: 0.0 ± 0.0
4.762TyrAsp: 4.762 ± 1.148
0.0TyrGlu: 0.0 ± 0.0
4.762TyrPhe: 4.762 ± 1.074
3.175TyrGly: 3.175 ± 2.198
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.587TyrLys: 1.587 ± 1.124
0.0TyrLeu: 0.0 ± 0.0
1.587TyrMet: 1.587 ± 1.124
1.587TyrAsn: 1.587 ± 1.099
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
4.762TyrArg: 4.762 ± 1.148
1.587TyrSer: 1.587 ± 1.124
0.0TyrThr: 0.0 ± 0.0
4.762TyrVal: 4.762 ± 1.148
3.175TyrTrp: 3.175 ± 0.025
1.587TyrTyr: 1.587 ± 1.124
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (631 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski