Amino acid dipepetide frequency for Canis familiaris papillomavirus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.973AlaAla: 5.973 ± 1.122
1.257AlaCys: 1.257 ± 0.529
3.144AlaAsp: 3.144 ± 0.942
3.144AlaGlu: 3.144 ± 1.005
3.458AlaPhe: 3.458 ± 0.748
3.772AlaGly: 3.772 ± 1.286
1.572AlaHis: 1.572 ± 0.224
2.515AlaIle: 2.515 ± 1.001
3.458AlaLys: 3.458 ± 0.837
5.344AlaLeu: 5.344 ± 1.778
1.572AlaMet: 1.572 ± 0.66
1.572AlaAsn: 1.572 ± 0.224
7.23AlaPro: 7.23 ± 2.378
3.144AlaGln: 3.144 ± 0.932
4.087AlaArg: 4.087 ± 1.102
4.087AlaSer: 4.087 ± 0.82
4.401AlaThr: 4.401 ± 1.001
2.829AlaVal: 2.829 ± 0.482
0.314AlaTrp: 0.314 ± 0.285
0.629AlaTyr: 0.629 ± 0.57
0.0AlaXaa: 0.0 ± 0.0
Cys
1.886CysAla: 1.886 ± 0.645
0.629CysCys: 0.629 ± 0.624
1.257CysAsp: 1.257 ± 0.962
0.314CysGlu: 0.314 ± 0.285
0.629CysPhe: 0.629 ± 0.471
0.943CysGly: 0.943 ± 0.659
0.943CysHis: 0.943 ± 0.308
1.572CysIle: 1.572 ± 0.785
1.257CysLys: 1.257 ± 0.366
1.257CysLeu: 1.257 ± 0.671
0.0CysMet: 0.0 ± 0.0
0.943CysAsn: 0.943 ± 0.666
2.829CysPro: 2.829 ± 0.775
0.314CysGln: 0.314 ± 0.415
0.943CysArg: 0.943 ± 0.682
1.886CysSer: 1.886 ± 1.107
1.886CysThr: 1.886 ± 1.312
0.629CysVal: 0.629 ± 0.489
0.629CysTrp: 0.629 ± 0.279
0.314CysTyr: 0.314 ± 0.224
0.0CysXaa: 0.0 ± 0.0
Asp
5.03AspAla: 5.03 ± 1.07
0.943AspCys: 0.943 ± 0.666
2.515AspAsp: 2.515 ± 0.74
2.515AspGlu: 2.515 ± 1.083
2.201AspPhe: 2.201 ± 0.592
2.829AspGly: 2.829 ± 0.498
0.943AspHis: 0.943 ± 0.683
3.144AspIle: 3.144 ± 0.742
0.943AspLys: 0.943 ± 0.406
5.03AspLeu: 5.03 ± 1.297
1.886AspMet: 1.886 ± 0.84
3.458AspAsn: 3.458 ± 0.55
4.715AspPro: 4.715 ± 1.048
1.572AspGln: 1.572 ± 0.644
3.458AspArg: 3.458 ± 0.771
6.916AspSer: 6.916 ± 0.834
4.087AspThr: 4.087 ± 0.595
3.144AspVal: 3.144 ± 1.253
1.572AspTrp: 1.572 ± 0.895
1.886AspTyr: 1.886 ± 0.561
0.0AspXaa: 0.0 ± 0.0
Glu
3.458GluAla: 3.458 ± 0.943
0.314GluCys: 0.314 ± 0.285
3.458GluAsp: 3.458 ± 1.741
9.117GluGlu: 9.117 ± 1.922
2.829GluPhe: 2.829 ± 0.473
4.087GluGly: 4.087 ± 1.47
1.886GluHis: 1.886 ± 0.623
1.886GluIle: 1.886 ± 0.689
1.572GluLys: 1.572 ± 0.52
4.087GluLeu: 4.087 ± 0.913
0.629GluMet: 0.629 ± 0.337
3.458GluAsn: 3.458 ± 0.785
4.401GluPro: 4.401 ± 1.218
2.829GluGln: 2.829 ± 0.555
3.458GluArg: 3.458 ± 1.504
3.144GluSer: 3.144 ± 0.792
3.144GluThr: 3.144 ± 0.9
2.515GluVal: 2.515 ± 0.538
0.314GluTrp: 0.314 ± 0.285
0.943GluTyr: 0.943 ± 0.309
0.0GluXaa: 0.0 ± 0.0
Phe
2.201PheAla: 2.201 ± 0.863
1.257PheCys: 1.257 ± 0.462
3.144PheAsp: 3.144 ± 1.086
1.886PheGlu: 1.886 ± 0.78
3.772PhePhe: 3.772 ± 1.039
3.458PheGly: 3.458 ± 0.499
0.0PheHis: 0.0 ± 0.0
2.201PheIle: 2.201 ± 0.812
1.886PheLys: 1.886 ± 1.146
3.458PheLeu: 3.458 ± 1.008
0.943PheMet: 0.943 ± 0.308
1.572PheAsn: 1.572 ± 0.515
1.886PhePro: 1.886 ± 0.525
1.572PheGln: 1.572 ± 0.528
3.144PheArg: 3.144 ± 1.086
3.458PheSer: 3.458 ± 0.925
0.314PheThr: 0.314 ± 0.285
3.144PheVal: 3.144 ± 0.771
1.886PheTrp: 1.886 ± 0.444
1.257PheTyr: 1.257 ± 0.963
0.0PheXaa: 0.0 ± 0.0
Gly
4.715GlyAla: 4.715 ± 1.556
0.943GlyCys: 0.943 ± 0.406
3.458GlyAsp: 3.458 ± 0.741
5.344GlyGlu: 5.344 ± 0.687
2.829GlyPhe: 2.829 ± 1.05
5.659GlyGly: 5.659 ± 1.788
1.572GlyHis: 1.572 ± 0.458
4.401GlyIle: 4.401 ± 0.989
1.572GlyLys: 1.572 ± 0.566
5.973GlyLeu: 5.973 ± 1.282
0.943GlyMet: 0.943 ± 0.572
5.03GlyAsn: 5.03 ± 1.396
4.715GlyPro: 4.715 ± 1.459
1.572GlyGln: 1.572 ± 0.519
4.087GlyArg: 4.087 ± 0.822
5.973GlySer: 5.973 ± 1.107
5.973GlyThr: 5.973 ± 0.484
4.401GlyVal: 4.401 ± 1.518
0.314GlyTrp: 0.314 ± 0.338
2.201GlyTyr: 2.201 ± 0.374
0.0GlyXaa: 0.0 ± 0.0
His
1.886HisAla: 1.886 ± 0.303
0.629HisCys: 0.629 ± 0.379
0.943HisAsp: 0.943 ± 0.406
0.0HisGlu: 0.0 ± 0.0
1.572HisPhe: 1.572 ± 0.501
1.257HisGly: 1.257 ± 0.995
1.257HisHis: 1.257 ± 0.486
0.629HisIle: 0.629 ± 0.389
0.943HisLys: 0.943 ± 0.504
0.314HisLeu: 0.314 ± 0.285
0.0HisMet: 0.0 ± 0.0
1.572HisAsn: 1.572 ± 0.458
1.257HisPro: 1.257 ± 0.425
0.314HisGln: 0.314 ± 0.338
0.943HisArg: 0.943 ± 0.742
2.515HisSer: 2.515 ± 0.698
2.201HisThr: 2.201 ± 0.403
1.572HisVal: 1.572 ± 0.611
0.943HisTrp: 0.943 ± 0.308
0.314HisTyr: 0.314 ± 0.285
0.0HisXaa: 0.0 ± 0.0
Ile
1.886IleAla: 1.886 ± 0.525
1.886IleCys: 1.886 ± 0.909
2.515IleAsp: 2.515 ± 0.767
1.257IleGlu: 1.257 ± 0.464
1.886IlePhe: 1.886 ± 0.766
3.144IleGly: 3.144 ± 1.079
0.314IleHis: 0.314 ± 0.333
1.572IleIle: 1.572 ± 0.67
0.943IleLys: 0.943 ± 0.481
2.829IleLeu: 2.829 ± 0.851
1.257IleMet: 1.257 ± 0.833
2.829IleAsn: 2.829 ± 0.99
3.458IlePro: 3.458 ± 1.043
1.886IleGln: 1.886 ± 0.531
2.201IleArg: 2.201 ± 0.726
4.715IleSer: 4.715 ± 0.775
1.886IleThr: 1.886 ± 0.484
3.458IleVal: 3.458 ± 0.604
0.0IleTrp: 0.0 ± 0.0
0.629IleTyr: 0.629 ± 0.389
0.0IleXaa: 0.0 ± 0.0
Lys
1.572LysAla: 1.572 ± 0.523
0.314LysCys: 0.314 ± 0.333
0.943LysAsp: 0.943 ± 0.487
2.201LysGlu: 2.201 ± 0.769
2.515LysPhe: 2.515 ± 0.835
2.515LysGly: 2.515 ± 0.467
1.572LysHis: 1.572 ± 1.188
1.886LysIle: 1.886 ± 0.62
4.087LysLys: 4.087 ± 0.828
1.886LysLeu: 1.886 ± 0.512
0.943LysMet: 0.943 ± 0.523
1.257LysAsn: 1.257 ± 0.378
0.943LysPro: 0.943 ± 0.481
2.201LysGln: 2.201 ± 0.588
4.087LysArg: 4.087 ± 1.099
4.087LysSer: 4.087 ± 1.435
2.201LysThr: 2.201 ± 0.602
2.515LysVal: 2.515 ± 0.647
0.629LysTrp: 0.629 ± 0.279
2.201LysTyr: 2.201 ± 0.472
0.0LysXaa: 0.0 ± 0.0
Leu
5.03LeuAla: 5.03 ± 0.642
2.515LeuCys: 2.515 ± 1.423
6.602LeuAsp: 6.602 ± 0.714
6.916LeuGlu: 6.916 ± 1.968
3.772LeuPhe: 3.772 ± 0.725
5.973LeuGly: 5.973 ± 1.632
2.201LeuHis: 2.201 ± 0.783
1.572LeuIle: 1.572 ± 0.459
3.458LeuLys: 3.458 ± 0.932
9.117LeuLeu: 9.117 ± 1.642
2.201LeuMet: 2.201 ± 0.812
2.201LeuAsn: 2.201 ± 0.812
6.287LeuPro: 6.287 ± 1.907
5.659LeuGln: 5.659 ± 0.717
5.973LeuArg: 5.973 ± 1.548
5.344LeuSer: 5.344 ± 1.351
6.916LeuThr: 6.916 ± 0.574
1.257LeuVal: 1.257 ± 0.577
1.257LeuTrp: 1.257 ± 0.665
2.201LeuTyr: 2.201 ± 1.068
0.0LeuXaa: 0.0 ± 0.0
Met
0.314MetAla: 0.314 ± 0.333
0.629MetCys: 0.629 ± 0.489
1.886MetAsp: 1.886 ± 0.384
0.943MetGlu: 0.943 ± 0.512
0.629MetPhe: 0.629 ± 0.279
1.257MetGly: 1.257 ± 0.593
0.0MetHis: 0.0 ± 0.0
0.943MetIle: 0.943 ± 0.532
0.629MetLys: 0.629 ± 0.489
1.257MetLeu: 1.257 ± 0.434
0.0MetMet: 0.0 ± 0.0
0.943MetAsn: 0.943 ± 0.421
0.0MetPro: 0.0 ± 0.0
0.943MetGln: 0.943 ± 0.999
1.257MetArg: 1.257 ± 0.848
2.829MetSer: 2.829 ± 1.304
0.943MetThr: 0.943 ± 0.472
2.201MetVal: 2.201 ± 0.726
0.314MetTrp: 0.314 ± 0.333
0.314MetTyr: 0.314 ± 0.224
0.0MetXaa: 0.0 ± 0.0
Asn
2.201AsnAla: 2.201 ± 1.063
0.629AsnCys: 0.629 ± 0.51
3.772AsnAsp: 3.772 ± 0.921
2.515AsnGlu: 2.515 ± 0.678
1.257AsnPhe: 1.257 ± 0.349
1.572AsnGly: 1.572 ± 0.501
0.0AsnHis: 0.0 ± 0.0
2.515AsnIle: 2.515 ± 0.775
1.886AsnLys: 1.886 ± 0.617
2.829AsnLeu: 2.829 ± 1.05
0.629AsnMet: 0.629 ± 0.279
1.257AsnAsn: 1.257 ± 0.366
4.087AsnPro: 4.087 ± 0.919
2.515AsnGln: 2.515 ± 1.034
2.829AsnArg: 2.829 ± 0.482
4.715AsnSer: 4.715 ± 0.865
2.201AsnThr: 2.201 ± 0.878
1.886AsnVal: 1.886 ± 0.359
0.314AsnTrp: 0.314 ± 0.285
0.629AsnTyr: 0.629 ± 0.57
0.0AsnXaa: 0.0 ± 0.0
Pro
6.916ProAla: 6.916 ± 2.235
2.515ProCys: 2.515 ± 1.025
4.715ProAsp: 4.715 ± 1.272
5.344ProGlu: 5.344 ± 1.842
2.515ProPhe: 2.515 ± 0.371
4.087ProGly: 4.087 ± 1.894
1.572ProHis: 1.572 ± 0.613
2.201ProIle: 2.201 ± 0.697
3.144ProLys: 3.144 ± 1.111
9.745ProLeu: 9.745 ± 2.075
0.629ProMet: 0.629 ± 0.783
2.829ProAsn: 2.829 ± 0.858
10.374ProPro: 10.374 ± 3.283
1.572ProGln: 1.572 ± 0.399
4.715ProArg: 4.715 ± 1.623
4.087ProSer: 4.087 ± 1.52
4.715ProThr: 4.715 ± 2.269
7.23ProVal: 7.23 ± 1.787
0.629ProTrp: 0.629 ± 0.486
1.572ProTyr: 1.572 ± 0.66
0.0ProXaa: 0.0 ± 0.0
Gln
4.715GlnAla: 4.715 ± 0.55
1.257GlnCys: 1.257 ± 0.671
2.515GlnAsp: 2.515 ± 0.86
3.144GlnGlu: 3.144 ± 0.689
1.886GlnPhe: 1.886 ± 0.573
2.515GlnGly: 2.515 ± 0.513
0.943GlnHis: 0.943 ± 0.595
1.572GlnIle: 1.572 ± 0.528
2.515GlnLys: 2.515 ± 0.47
5.344GlnLeu: 5.344 ± 0.89
0.629GlnMet: 0.629 ± 0.266
1.257GlnAsn: 1.257 ± 0.48
3.458GlnPro: 3.458 ± 0.876
1.257GlnGln: 1.257 ± 0.524
2.829GlnArg: 2.829 ± 0.603
1.886GlnSer: 1.886 ± 0.444
1.886GlnThr: 1.886 ± 0.607
2.201GlnVal: 2.201 ± 0.626
1.257GlnTrp: 1.257 ± 0.979
1.886GlnTyr: 1.886 ± 0.629
0.0GlnXaa: 0.0 ± 0.0
Arg
4.715ArgAla: 4.715 ± 1.162
1.572ArgCys: 1.572 ± 0.615
3.144ArgAsp: 3.144 ± 0.818
4.087ArgGlu: 4.087 ± 0.967
3.144ArgPhe: 3.144 ± 0.763
4.401ArgGly: 4.401 ± 1.444
2.201ArgHis: 2.201 ± 0.612
1.572ArgIle: 1.572 ± 0.582
2.201ArgLys: 2.201 ± 0.413
6.602ArgLeu: 6.602 ± 2.368
1.257ArgMet: 1.257 ± 0.504
2.515ArgAsn: 2.515 ± 0.699
5.03ArgPro: 5.03 ± 1.834
2.201ArgGln: 2.201 ± 0.852
7.545ArgArg: 7.545 ± 2.667
3.772ArgSer: 3.772 ± 0.908
4.087ArgThr: 4.087 ± 0.885
4.087ArgVal: 4.087 ± 1.19
0.943ArgTrp: 0.943 ± 0.512
3.772ArgTyr: 3.772 ± 0.534
0.0ArgXaa: 0.0 ± 0.0
Ser
3.458SerAla: 3.458 ± 0.691
0.943SerCys: 0.943 ± 0.308
5.03SerAsp: 5.03 ± 1.01
3.458SerGlu: 3.458 ± 1.719
1.257SerPhe: 1.257 ± 0.774
9.117SerGly: 9.117 ± 1.156
2.201SerHis: 2.201 ± 0.696
3.772SerIle: 3.772 ± 0.85
2.201SerLys: 2.201 ± 0.928
6.916SerLeu: 6.916 ± 0.947
1.886SerMet: 1.886 ± 0.607
2.829SerAsn: 2.829 ± 0.591
6.916SerPro: 6.916 ± 1.971
5.973SerGln: 5.973 ± 1.033
4.715SerArg: 4.715 ± 1.002
6.287SerSer: 6.287 ± 1.733
4.401SerThr: 4.401 ± 1.066
5.659SerVal: 5.659 ± 0.96
0.629SerTrp: 0.629 ± 0.393
0.943SerTyr: 0.943 ± 0.309
0.0SerXaa: 0.0 ± 0.0
Thr
2.201ThrAla: 2.201 ± 0.614
1.886ThrCys: 1.886 ± 0.726
3.144ThrAsp: 3.144 ± 1.115
1.572ThrGlu: 1.572 ± 0.515
2.201ThrPhe: 2.201 ± 0.598
5.344ThrGly: 5.344 ± 1.116
0.314ThrHis: 0.314 ± 0.224
2.201ThrIle: 2.201 ± 0.403
2.829ThrLys: 2.829 ± 0.656
6.287ThrLeu: 6.287 ± 1.494
1.572ThrMet: 1.572 ± 0.779
2.515ThrAsn: 2.515 ± 0.555
6.287ThrPro: 6.287 ± 1.624
4.087ThrGln: 4.087 ± 1.534
4.401ThrArg: 4.401 ± 0.761
4.715ThrSer: 4.715 ± 0.715
4.401ThrThr: 4.401 ± 1.99
4.087ThrVal: 4.087 ± 1.636
0.943ThrTrp: 0.943 ± 0.512
1.886ThrTyr: 1.886 ± 0.589
0.0ThrXaa: 0.0 ± 0.0
Val
3.458ValAla: 3.458 ± 0.856
0.314ValCys: 0.314 ± 0.415
5.344ValAsp: 5.344 ± 1.531
2.201ValGlu: 2.201 ± 0.521
2.201ValPhe: 2.201 ± 0.833
5.973ValGly: 5.973 ± 1.495
0.943ValHis: 0.943 ± 0.351
1.886ValIle: 1.886 ± 0.359
2.515ValLys: 2.515 ± 0.527
4.087ValLeu: 4.087 ± 1.197
0.629ValMet: 0.629 ± 0.57
0.314ValAsn: 0.314 ± 0.333
5.03ValPro: 5.03 ± 1.433
3.144ValGln: 3.144 ± 1.394
3.458ValArg: 3.458 ± 1.241
5.973ValSer: 5.973 ± 1.763
5.344ValThr: 5.344 ± 1.184
2.829ValVal: 2.829 ± 1.067
1.257ValTrp: 1.257 ± 0.559
1.886ValTyr: 1.886 ± 0.542
0.0ValXaa: 0.0 ± 0.0
Trp
0.943TrpAla: 0.943 ± 0.666
0.314TrpCys: 0.314 ± 0.41
0.629TrpAsp: 0.629 ± 0.389
0.629TrpGlu: 0.629 ± 0.552
0.629TrpPhe: 0.629 ± 0.465
1.257TrpGly: 1.257 ± 0.559
0.314TrpHis: 0.314 ± 0.333
0.314TrpIle: 0.314 ± 0.285
0.943TrpLys: 0.943 ± 0.683
1.886TrpLeu: 1.886 ± 0.617
0.314TrpMet: 0.314 ± 0.333
0.629TrpAsn: 0.629 ± 0.279
0.943TrpPro: 0.943 ± 0.421
0.629TrpGln: 0.629 ± 0.666
1.257TrpArg: 1.257 ± 0.847
1.257TrpSer: 1.257 ± 0.417
0.314TrpThr: 0.314 ± 0.333
1.257TrpVal: 1.257 ± 0.524
0.0TrpTrp: 0.0 ± 0.0
0.629TrpTyr: 0.629 ± 0.389
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.943TyrAla: 0.943 ± 0.595
0.314TyrCys: 0.314 ± 0.415
0.629TyrAsp: 0.629 ± 0.389
0.943TyrGlu: 0.943 ± 0.306
1.257TyrPhe: 1.257 ± 0.612
2.515TyrGly: 2.515 ± 0.873
0.314TyrHis: 0.314 ± 0.224
2.201TyrIle: 2.201 ± 0.663
1.886TyrLys: 1.886 ± 0.832
2.201TyrLeu: 2.201 ± 0.602
0.0TyrMet: 0.0 ± 0.0
1.257TyrAsn: 1.257 ± 0.524
1.257TyrPro: 1.257 ± 0.593
1.572TyrGln: 1.572 ± 0.52
3.458TyrArg: 3.458 ± 0.647
0.943TyrSer: 0.943 ± 0.4
1.572TyrThr: 1.572 ± 0.783
1.886TyrVal: 1.886 ± 0.542
0.943TyrTrp: 0.943 ± 0.308
1.572TyrTyr: 1.572 ± 0.61
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (3182 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski