Amino acid dipepetide frequency for Lachnellula willkommii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.54AlaAla: 8.54 ± 0.07	0.978AlaCys: 0.978 ± 0.014	4.062AlaAsp: 4.062 ± 0.032	5.103AlaGlu: 5.103 ± 0.041	3.21AlaPhe: 3.21 ± 0.03	5.957AlaGly: 5.957 ± 0.041	1.66AlaHis: 1.66 ± 0.02	4.481AlaIle: 4.481 ± 0.036	4.396AlaLys: 4.396 ± 0.04	7.737AlaLeu: 7.737 ± 0.05	1.94AlaMet: 1.94 ± 0.021	3.082AlaAsn: 3.082 ± 0.029	4.597AlaPro: 4.597 ± 0.043	3.212AlaGln: 3.212 ± 0.031	4.49AlaArg: 4.49 ± 0.034	7.292AlaSer: 7.292 ± 0.051	5.225AlaThr: 5.225 ± 0.034	5.295AlaVal: 5.295 ± 0.036	1.131AlaTrp: 1.131 ± 0.018	2.19AlaTyr: 2.19 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.848CysAla: 0.848 ± 0.014	0.199CysCys: 0.199 ± 0.007	0.579CysAsp: 0.579 ± 0.012	0.546CysGlu: 0.546 ± 0.015	0.533CysPhe: 0.533 ± 0.012	0.877CysGly: 0.877 ± 0.015	0.284CysHis: 0.284 ± 0.008	0.688CysIle: 0.688 ± 0.014	0.51CysLys: 0.51 ± 0.012	1.154CysLeu: 1.154 ± 0.017	0.249CysMet: 0.249 ± 0.008	0.405CysAsn: 0.405 ± 0.011	0.571CysPro: 0.571 ± 0.014	0.385CysGln: 0.385 ± 0.01	0.61CysArg: 0.61 ± 0.014	0.827CysSer: 0.827 ± 0.015	0.645CysThr: 0.645 ± 0.015	0.731CysVal: 0.731 ± 0.014	0.186CysTrp: 0.186 ± 0.006	0.343CysTyr: 0.343 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.53AspAla: 4.53 ± 0.036	0.584AspCys: 0.584 ± 0.012	3.967AspAsp: 3.967 ± 0.041	4.506AspGlu: 4.506 ± 0.038	2.352AspPhe: 2.352 ± 0.022	4.073AspGly: 4.073 ± 0.032	1.127AspHis: 1.127 ± 0.017	3.186AspIle: 3.186 ± 0.028	2.442AspLys: 2.442 ± 0.027	5.048AspLeu: 5.048 ± 0.035	1.241AspMet: 1.241 ± 0.017	1.891AspAsn: 1.891 ± 0.022	3.159AspPro: 3.159 ± 0.03	1.755AspGln: 1.755 ± 0.023	2.734AspArg: 2.734 ± 0.027	4.109AspSer: 4.109 ± 0.038	2.924AspThr: 2.924 ± 0.029	3.692AspVal: 3.692 ± 0.032	0.854AspTrp: 0.854 ± 0.015	1.606AspTyr: 1.606 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.361GluAla: 5.361 ± 0.046	0.561GluCys: 0.561 ± 0.013	4.277GluAsp: 4.277 ± 0.04	5.651GluGlu: 5.651 ± 0.059	2.053GluPhe: 2.053 ± 0.024	4.015GluGly: 4.015 ± 0.037	1.347GluHis: 1.347 ± 0.019	3.291GluIle: 3.291 ± 0.026	4.15GluLys: 4.15 ± 0.042	5.171GluLeu: 5.171 ± 0.044	1.539GluMet: 1.539 ± 0.02	2.475GluAsn: 2.475 ± 0.025	2.617GluPro: 2.617 ± 0.033	2.355GluGln: 2.355 ± 0.027	3.778GluArg: 3.778 ± 0.04	4.398GluSer: 4.398 ± 0.039	3.434GluThr: 3.434 ± 0.032	3.771GluVal: 3.771 ± 0.031	0.892GluTrp: 0.892 ± 0.016	1.721GluTyr: 1.721 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.145PheAla: 3.145 ± 0.031	0.539PheCys: 0.539 ± 0.011	2.329PheAsp: 2.329 ± 0.023	2.313PheGlu: 2.313 ± 0.024	1.676PhePhe: 1.676 ± 0.023	3.042PheGly: 3.042 ± 0.032	0.88PheHis: 0.88 ± 0.014	1.914PheIle: 1.914 ± 0.026	1.7PheLys: 1.7 ± 0.023	3.578PheLeu: 3.578 ± 0.033	0.817PheMet: 0.817 ± 0.013	1.534PheAsn: 1.534 ± 0.022	1.99PhePro: 1.99 ± 0.024	1.453PheGln: 1.453 ± 0.021	1.854PheArg: 1.854 ± 0.02	3.152PheSer: 3.152 ± 0.029	2.306PheThr: 2.306 ± 0.026	2.458PheVal: 2.458 ± 0.025	0.656PheTrp: 0.656 ± 0.013	1.161PheTyr: 1.161 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.461GlyAla: 5.461 ± 0.041	0.815GlyCys: 0.815 ± 0.014	3.718GlyAsp: 3.718 ± 0.029	3.931GlyGlu: 3.931 ± 0.036	3.021GlyPhe: 3.021 ± 0.028	6.15GlyGly: 6.15 ± 0.058	1.61GlyHis: 1.61 ± 0.021	3.846GlyIle: 3.846 ± 0.038	3.925GlyLys: 3.925 ± 0.035	6.171GlyLeu: 6.171 ± 0.041	1.738GlyMet: 1.738 ± 0.022	2.753GlyAsn: 2.753 ± 0.028	3.245GlyPro: 3.245 ± 0.033	2.446GlyGln: 2.446 ± 0.027	3.902GlyArg: 3.902 ± 0.034	5.896GlySer: 5.896 ± 0.045	4.2GlyThr: 4.2 ± 0.032	4.61GlyVal: 4.61 ± 0.04	1.159GlyTrp: 1.159 ± 0.017	2.169GlyTyr: 2.169 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	1.71HisAla: 1.71 ± 0.02	0.291HisCys: 0.291 ± 0.008	1.209HisAsp: 1.209 ± 0.017	1.281HisGlu: 1.281 ± 0.017	0.907HisPhe: 0.907 ± 0.014	1.607HisGly: 1.607 ± 0.022	0.759HisHis: 0.759 ± 0.016	1.183HisIle: 1.183 ± 0.017	0.962HisLys: 0.962 ± 0.017	2.152HisLeu: 2.152 ± 0.022	0.46HisMet: 0.46 ± 0.01	0.903HisAsn: 0.903 ± 0.017	1.554HisPro: 1.554 ± 0.021	0.918HisGln: 0.918 ± 0.016	1.351HisArg: 1.351 ± 0.02	1.765HisSer: 1.765 ± 0.024	1.264HisThr: 1.264 ± 0.017	1.353HisVal: 1.353 ± 0.016	0.319HisTrp: 0.319 ± 0.009	0.66HisTyr: 0.66 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.45IleAla: 4.45 ± 0.035	0.722IleCys: 0.722 ± 0.012	2.977IleAsp: 2.977 ± 0.029	3.057IleGlu: 3.057 ± 0.032	2.133IlePhe: 2.133 ± 0.026	3.511IleGly: 3.511 ± 0.039	1.228IleHis: 1.228 ± 0.015	2.819IleIle: 2.819 ± 0.03	2.494IleLys: 2.494 ± 0.025	4.807IleLeu: 4.807 ± 0.042	1.108IleMet: 1.108 ± 0.016	1.947IleAsn: 1.947 ± 0.024	3.236IlePro: 3.236 ± 0.029	1.97IleGln: 1.97 ± 0.022	2.692IleArg: 2.692 ± 0.025	4.197IleSer: 4.197 ± 0.033	3.059IleThr: 3.059 ± 0.026	3.298IleVal: 3.298 ± 0.033	0.752IleTrp: 0.752 ± 0.013	1.5IleTyr: 1.5 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	4.74LysAla: 4.74 ± 0.039	0.478LysCys: 0.478 ± 0.01	3.099LysAsp: 3.099 ± 0.029	3.816LysGlu: 3.816 ± 0.04	1.644LysPhe: 1.644 ± 0.019	3.394LysGly: 3.394 ± 0.031	1.195LysHis: 1.195 ± 0.018	2.588LysIle: 2.588 ± 0.027	3.865LysLys: 3.865 ± 0.062	4.386LysLeu: 4.386 ± 0.036	1.121LysMet: 1.121 ± 0.016	1.975LysAsn: 1.975 ± 0.021	2.883LysPro: 2.883 ± 0.03	1.896LysGln: 1.896 ± 0.019	3.417LysArg: 3.417 ± 0.038	3.955LysSer: 3.955 ± 0.04	3.12LysThr: 3.12 ± 0.027	3.161LysVal: 3.161 ± 0.032	0.717LysTrp: 0.717 ± 0.011	1.48LysTyr: 1.48 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	7.642LeuAla: 7.642 ± 0.046	1.151LeuCys: 1.151 ± 0.017	5.131LeuAsp: 5.131 ± 0.038	5.6LeuGlu: 5.6 ± 0.046	3.372LeuPhe: 3.372 ± 0.032	6.09LeuGly: 6.09 ± 0.044	2.146LeuHis: 2.146 ± 0.024	4.138LeuIle: 4.138 ± 0.036	4.64LeuLys: 4.64 ± 0.04	8.408LeuLeu: 8.408 ± 0.06	1.785LeuMet: 1.785 ± 0.02	3.305LeuAsn: 3.305 ± 0.028	5.373LeuPro: 5.373 ± 0.039	3.77LeuGln: 3.77 ± 0.037	5.279LeuArg: 5.279 ± 0.036	7.253LeuSer: 7.253 ± 0.043	4.881LeuThr: 4.881 ± 0.036	5.357LeuVal: 5.357 ± 0.042	1.163LeuTrp: 1.163 ± 0.018	2.367LeuTyr: 2.367 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.19MetAla: 2.19 ± 0.023	0.23MetCys: 0.23 ± 0.007	1.26MetAsp: 1.26 ± 0.016	1.297MetGlu: 1.297 ± 0.019	0.795MetPhe: 0.795 ± 0.014	1.584MetGly: 1.584 ± 0.022	0.468MetHis: 0.468 ± 0.011	1.059MetIle: 1.059 ± 0.016	1.115MetLys: 1.115 ± 0.015	1.867MetLeu: 1.867 ± 0.022	0.598MetMet: 0.598 ± 0.012	0.853MetAsn: 0.853 ± 0.014	1.232MetPro: 1.232 ± 0.016	0.867MetGln: 0.867 ± 0.014	1.18MetArg: 1.18 ± 0.017	1.896MetSer: 1.896 ± 0.02	1.293MetThr: 1.293 ± 0.017	1.321MetVal: 1.321 ± 0.018	0.261MetTrp: 0.261 ± 0.008	0.525MetTyr: 0.525 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.248AsnAla: 3.248 ± 0.029	0.423AsnCys: 0.423 ± 0.01	1.993AsnAsp: 1.993 ± 0.02	2.095AsnGlu: 2.095 ± 0.02	1.52AsnPhe: 1.52 ± 0.02	3.378AsnGly: 3.378 ± 0.035	0.874AsnHis: 0.874 ± 0.015	2.276AsnIle: 2.276 ± 0.023	1.679AsnLys: 1.679 ± 0.021	3.411AsnLeu: 3.411 ± 0.035	0.882AsnMet: 0.882 ± 0.015	1.536AsnAsn: 1.536 ± 0.02	2.511AsnPro: 2.511 ± 0.027	1.362AsnGln: 1.362 ± 0.021	1.849AsnArg: 1.849 ± 0.021	3.078AsnSer: 3.078 ± 0.03	2.451AsnThr: 2.451 ± 0.026	2.375AsnVal: 2.375 ± 0.025	0.567AsnTrp: 0.567 ± 0.012	1.11AsnTyr: 1.11 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	4.874ProAla: 4.874 ± 0.047	0.432ProCys: 0.432 ± 0.011	2.932ProAsp: 2.932 ± 0.027	3.769ProGlu: 3.769 ± 0.037	2.076ProPhe: 2.076 ± 0.027	3.758ProGly: 3.758 ± 0.03	1.229ProHis: 1.229 ± 0.017	2.729ProIle: 2.729 ± 0.03	2.964ProLys: 2.964 ± 0.03	4.606ProLeu: 4.606 ± 0.034	1.034ProMet: 1.034 ± 0.017	2.292ProAsn: 2.292 ± 0.027	4.666ProPro: 4.666 ± 0.066	2.412ProGln: 2.412 ± 0.034	3.109ProArg: 3.109 ± 0.033	5.712ProSer: 5.712 ± 0.055	3.932ProThr: 3.932 ± 0.033	3.428ProVal: 3.428 ± 0.032	0.685ProTrp: 0.685 ± 0.013	1.499ProTyr: 1.499 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.331GlnAla: 3.331 ± 0.035	0.397GlnCys: 0.397 ± 0.01	1.985GlnAsp: 1.985 ± 0.023	2.37GlnGlu: 2.37 ± 0.025	1.288GlnPhe: 1.288 ± 0.017	2.372GlnGly: 2.372 ± 0.026	1.001GlnHis: 1.001 ± 0.018	1.95GlnIle: 1.95 ± 0.018	2.135GlnLys: 2.135 ± 0.026	3.253GlnLeu: 3.253 ± 0.028	0.883GlnMet: 0.883 ± 0.017	1.684GlnAsn: 1.684 ± 0.022	2.176GlnPro: 2.176 ± 0.031	2.134GlnGln: 2.134 ± 0.045	2.423GlnArg: 2.423 ± 0.024	3.053GlnSer: 3.053 ± 0.029	2.287GlnThr: 2.287 ± 0.024	2.112GlnVal: 2.112 ± 0.024	0.549GlnTrp: 0.549 ± 0.011	1.202GlnTyr: 1.202 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.251ArgAla: 4.251 ± 0.039	0.582ArgCys: 0.582 ± 0.012	3.097ArgAsp: 3.097 ± 0.03	3.658ArgGlu: 3.658 ± 0.041	2.032ArgPhe: 2.032 ± 0.021	3.61ArgGly: 3.61 ± 0.041	1.357ArgHis: 1.357 ± 0.019	2.856ArgIle: 2.856 ± 0.03	3.563ArgLys: 3.563 ± 0.031	4.915ArgLeu: 4.915 ± 0.04	1.258ArgMet: 1.258 ± 0.018	2.235ArgAsn: 2.235 ± 0.024	3.112ArgPro: 3.112 ± 0.034	2.317ArgGln: 2.317 ± 0.028	4.319ArgArg: 4.319 ± 0.046	4.378ArgSer: 4.378 ± 0.042	3.087ArgThr: 3.087 ± 0.026	3.124ArgVal: 3.124 ± 0.027	0.843ArgTrp: 0.843 ± 0.015	1.53ArgTyr: 1.53 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.645SerAla: 6.645 ± 0.051	0.787SerCys: 0.787 ± 0.016	4.107SerAsp: 4.107 ± 0.033	4.281SerGlu: 4.281 ± 0.038	3.119SerPhe: 3.119 ± 0.032	5.724SerGly: 5.724 ± 0.043	1.846SerHis: 1.846 ± 0.025	4.322SerIle: 4.322 ± 0.038	4.247SerLys: 4.247 ± 0.04	7.147SerLeu: 7.147 ± 0.043	1.748SerMet: 1.748 ± 0.023	3.319SerAsn: 3.319 ± 0.032	5.359SerPro: 5.359 ± 0.057	3.274SerGln: 3.274 ± 0.034	4.651SerArg: 4.651 ± 0.041	8.835SerSer: 8.835 ± 0.086	5.807SerThr: 5.807 ± 0.05	4.576SerVal: 4.576 ± 0.037	1.083SerTrp: 1.083 ± 0.017	2.2SerTyr: 2.2 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.188ThrAla: 5.188 ± 0.04	0.679ThrCys: 0.679 ± 0.013	2.783ThrAsp: 2.783 ± 0.028	3.097ThrGlu: 3.097 ± 0.025	2.434ThrPhe: 2.434 ± 0.025	4.302ThrGly: 4.302 ± 0.039	1.265ThrHis: 1.265 ± 0.018	3.305ThrIle: 3.305 ± 0.03	2.875ThrLys: 2.875 ± 0.027	5.383ThrLeu: 5.383 ± 0.036	1.182ThrMet: 1.182 ± 0.016	2.328ThrAsn: 2.328 ± 0.025	4.375ThrPro: 4.375 ± 0.042	2.085ThrGln: 2.085 ± 0.022	2.97ThrArg: 2.97 ± 0.027	5.569ThrSer: 5.569 ± 0.045	4.269ThrThr: 4.269 ± 0.037	3.634ThrVal: 3.634 ± 0.033	0.833ThrTrp: 0.833 ± 0.014	1.685ThrTyr: 1.685 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.126ValAla: 5.126 ± 0.039	0.741ValCys: 0.741 ± 0.014	3.719ValAsp: 3.719 ± 0.032	3.996ValGlu: 3.996 ± 0.032	2.533ValPhe: 2.533 ± 0.026	4.235ValGly: 4.235 ± 0.038	1.283ValHis: 1.283 ± 0.019	3.045ValIle: 3.045 ± 0.03	3.24ValLys: 3.24 ± 0.031	5.656ValLeu: 5.656 ± 0.045	1.337ValMet: 1.337 ± 0.018	2.29ValAsn: 2.29 ± 0.026	3.451ValPro: 3.451 ± 0.028	2.311ValGln: 2.311 ± 0.023	3.174ValArg: 3.174 ± 0.027	4.623ValSer: 4.623 ± 0.031	3.439ValThr: 3.439 ± 0.03	4.304ValVal: 4.304 ± 0.036	0.858ValTrp: 0.858 ± 0.014	1.723ValTyr: 1.723 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.095TrpAla: 1.095 ± 0.017	0.181TrpCys: 0.181 ± 0.007	0.901TrpAsp: 0.901 ± 0.015	0.852TrpGlu: 0.852 ± 0.015	0.543TrpPhe: 0.543 ± 0.013	0.961TrpGly: 0.961 ± 0.017	0.333TrpHis: 0.333 ± 0.009	0.783TrpIle: 0.783 ± 0.015	0.797TrpLys: 0.797 ± 0.013	1.275TrpLeu: 1.275 ± 0.019	0.368TrpMet: 0.368 ± 0.009	0.656TrpAsn: 0.656 ± 0.012	0.573TrpPro: 0.573 ± 0.013	0.555TrpGln: 0.555 ± 0.012	0.865TrpArg: 0.865 ± 0.015	0.998TrpSer: 0.998 ± 0.015	0.915TrpThr: 0.915 ± 0.015	0.865TrpVal: 0.865 ± 0.015	0.265TrpTrp: 0.265 ± 0.009	0.431TrpTyr: 0.431 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.203TyrAla: 2.203 ± 0.023	0.403TyrCys: 0.403 ± 0.01	1.654TyrAsp: 1.654 ± 0.017	1.637TyrGlu: 1.637 ± 0.019	1.256TyrPhe: 1.256 ± 0.015	2.126TyrGly: 2.126 ± 0.025	0.713TyrHis: 0.713 ± 0.012	1.501TyrIle: 1.501 ± 0.018	1.226TyrLys: 1.226 ± 0.016	2.725TyrLeu: 2.725 ± 0.027	0.605TyrMet: 0.605 ± 0.011	1.154TyrAsn: 1.154 ± 0.019	1.461TyrPro: 1.461 ± 0.022	1.11TyrGln: 1.11 ± 0.018	1.477TyrArg: 1.477 ± 0.018	2.091TyrSer: 2.091 ± 0.024	1.703TyrThr: 1.703 ± 0.022	1.621TyrVal: 1.621 ± 0.018	0.437TyrTrp: 0.437 ± 0.012	0.933TyrTyr: 0.933 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8978 proteins (4323907 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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