Amino acid dipepetide frequency for Salmonella virus KFS-SE2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.829AlaAla: 8.829 ± 1.249
0.483AlaCys: 0.483 ± 0.161
4.345AlaAsp: 4.345 ± 0.616
6.691AlaGlu: 6.691 ± 0.851
2.138AlaPhe: 2.138 ± 0.408
6.484AlaGly: 6.484 ± 0.607
0.966AlaHis: 0.966 ± 0.28
5.449AlaIle: 5.449 ± 0.527
5.518AlaLys: 5.518 ± 0.643
6.553AlaLeu: 6.553 ± 0.876
2.966AlaMet: 2.966 ± 0.525
3.518AlaAsn: 3.518 ± 0.537
1.862AlaPro: 1.862 ± 0.297
3.656AlaGln: 3.656 ± 0.637
4.483AlaArg: 4.483 ± 0.499
4.621AlaSer: 4.621 ± 0.735
4.414AlaThr: 4.414 ± 0.791
6.346AlaVal: 6.346 ± 0.795
1.38AlaTrp: 1.38 ± 0.255
2.207AlaTyr: 2.207 ± 0.376
0.069AlaXaa: 0.069 ± 0.072
Cys
1.173CysAla: 1.173 ± 0.257
0.552CysCys: 0.552 ± 0.2
1.173CysAsp: 1.173 ± 0.248
1.517CysGlu: 1.517 ± 0.367
0.828CysPhe: 0.828 ± 0.252
1.862CysGly: 1.862 ± 0.44
0.621CysHis: 0.621 ± 0.202
0.897CysIle: 0.897 ± 0.261
1.104CysLys: 1.104 ± 0.242
1.311CysLeu: 1.311 ± 0.327
0.207CysMet: 0.207 ± 0.119
0.759CysAsn: 0.759 ± 0.288
0.483CysPro: 0.483 ± 0.175
0.345CysGln: 0.345 ± 0.153
0.552CysArg: 0.552 ± 0.206
0.897CysSer: 0.897 ± 0.298
0.414CysThr: 0.414 ± 0.174
0.414CysVal: 0.414 ± 0.173
0.276CysTrp: 0.276 ± 0.15
0.483CysTyr: 0.483 ± 0.21
0.0CysXaa: 0.0 ± 0.0
Asp
6.07AspAla: 6.07 ± 0.686
0.759AspCys: 0.759 ± 0.241
4.483AspAsp: 4.483 ± 0.76
5.035AspGlu: 5.035 ± 0.632
3.38AspPhe: 3.38 ± 0.482
5.932AspGly: 5.932 ± 0.853
0.828AspHis: 0.828 ± 0.216
4.483AspIle: 4.483 ± 0.532
3.863AspLys: 3.863 ± 0.507
2.897AspLeu: 2.897 ± 0.417
2.207AspMet: 2.207 ± 0.388
2.966AspAsn: 2.966 ± 0.396
1.655AspPro: 1.655 ± 0.273
0.897AspGln: 0.897 ± 0.223
2.966AspArg: 2.966 ± 0.408
3.035AspSer: 3.035 ± 0.508
3.587AspThr: 3.587 ± 0.476
4.276AspVal: 4.276 ± 0.568
0.621AspTrp: 0.621 ± 0.201
2.828AspTyr: 2.828 ± 0.458
0.0AspXaa: 0.0 ± 0.0
Glu
5.035GluAla: 5.035 ± 0.51
1.38GluCys: 1.38 ± 0.298
3.863GluAsp: 3.863 ± 0.51
4.828GluGlu: 4.828 ± 0.659
2.069GluPhe: 2.069 ± 0.466
3.173GluGly: 3.173 ± 0.457
0.621GluHis: 0.621 ± 0.258
5.518GluIle: 5.518 ± 0.442
4.207GluLys: 4.207 ± 0.645
5.863GluLeu: 5.863 ± 0.617
2.897GluMet: 2.897 ± 0.447
2.759GluAsn: 2.759 ± 0.432
2.138GluPro: 2.138 ± 0.483
4.345GluGln: 4.345 ± 0.566
3.173GluArg: 3.173 ± 0.577
3.794GluSer: 3.794 ± 0.473
2.69GluThr: 2.69 ± 0.397
3.725GluVal: 3.725 ± 0.506
1.448GluTrp: 1.448 ± 0.285
2.552GluTyr: 2.552 ± 0.422
0.0GluXaa: 0.0 ± 0.0
Phe
2.0PheAla: 2.0 ± 0.418
0.897PheCys: 0.897 ± 0.205
3.242PheAsp: 3.242 ± 0.439
2.345PheGlu: 2.345 ± 0.361
1.311PhePhe: 1.311 ± 0.401
2.483PheGly: 2.483 ± 0.343
0.759PheHis: 0.759 ± 0.249
2.345PheIle: 2.345 ± 0.521
1.793PheLys: 1.793 ± 0.339
1.862PheLeu: 1.862 ± 0.367
1.448PheMet: 1.448 ± 0.321
2.552PheAsn: 2.552 ± 0.462
1.38PhePro: 1.38 ± 0.344
1.173PheGln: 1.173 ± 0.229
1.586PheArg: 1.586 ± 0.348
2.207PheSer: 2.207 ± 0.447
2.207PheThr: 2.207 ± 0.391
2.0PheVal: 2.0 ± 0.323
0.345PheTrp: 0.345 ± 0.16
1.311PheTyr: 1.311 ± 0.31
0.0PheXaa: 0.0 ± 0.0
Gly
4.759GlyAla: 4.759 ± 0.685
1.035GlyCys: 1.035 ± 0.274
4.414GlyAsp: 4.414 ± 0.529
4.414GlyGlu: 4.414 ± 0.47
2.552GlyPhe: 2.552 ± 0.343
5.725GlyGly: 5.725 ± 0.764
1.724GlyHis: 1.724 ± 0.38
5.38GlyIle: 5.38 ± 0.597
5.863GlyLys: 5.863 ± 0.661
4.621GlyLeu: 4.621 ± 0.536
2.138GlyMet: 2.138 ± 0.367
3.38GlyAsn: 3.38 ± 0.463
0.621GlyPro: 0.621 ± 0.193
2.483GlyGln: 2.483 ± 0.458
3.794GlyArg: 3.794 ± 0.519
5.518GlySer: 5.518 ± 0.926
4.001GlyThr: 4.001 ± 0.561
5.518GlyVal: 5.518 ± 0.721
1.104GlyTrp: 1.104 ± 0.257
4.001GlyTyr: 4.001 ± 0.52
0.0GlyXaa: 0.0 ± 0.0
His
1.173HisAla: 1.173 ± 0.338
0.414HisCys: 0.414 ± 0.171
1.173HisAsp: 1.173 ± 0.255
1.035HisGlu: 1.035 ± 0.273
0.759HisPhe: 0.759 ± 0.236
1.862HisGly: 1.862 ± 0.412
0.483HisHis: 0.483 ± 0.198
0.966HisIle: 0.966 ± 0.268
1.517HisLys: 1.517 ± 0.344
1.104HisLeu: 1.104 ± 0.239
0.483HisMet: 0.483 ± 0.2
0.69HisAsn: 0.69 ± 0.184
0.69HisPro: 0.69 ± 0.178
0.759HisGln: 0.759 ± 0.248
1.448HisArg: 1.448 ± 0.421
1.035HisSer: 1.035 ± 0.277
0.69HisThr: 0.69 ± 0.276
1.311HisVal: 1.311 ± 0.367
0.069HisTrp: 0.069 ± 0.071
1.104HisTyr: 1.104 ± 0.262
0.0HisXaa: 0.0 ± 0.0
Ile
4.966IleAla: 4.966 ± 0.629
1.448IleCys: 1.448 ± 0.348
5.38IleAsp: 5.38 ± 0.555
5.035IleGlu: 5.035 ± 0.566
2.207IlePhe: 2.207 ± 0.351
4.966IleGly: 4.966 ± 0.674
1.173IleHis: 1.173 ± 0.261
4.07IleIle: 4.07 ± 0.574
4.207IleLys: 4.207 ± 0.554
4.07IleLeu: 4.07 ± 0.498
1.793IleMet: 1.793 ± 0.389
3.38IleAsn: 3.38 ± 0.498
2.621IlePro: 2.621 ± 0.358
1.862IleGln: 1.862 ± 0.364
3.794IleArg: 3.794 ± 0.492
4.414IleSer: 4.414 ± 0.558
3.725IleThr: 3.725 ± 0.581
4.966IleVal: 4.966 ± 0.436
0.483IleTrp: 0.483 ± 0.183
1.586IleTyr: 1.586 ± 0.401
0.0IleXaa: 0.0 ± 0.0
Lys
6.415LysAla: 6.415 ± 0.638
1.035LysCys: 1.035 ± 0.272
3.656LysAsp: 3.656 ± 0.538
3.518LysGlu: 3.518 ± 0.456
2.276LysPhe: 2.276 ± 0.482
3.449LysGly: 3.449 ± 0.613
1.586LysHis: 1.586 ± 0.485
3.656LysIle: 3.656 ± 0.523
4.207LysLys: 4.207 ± 0.547
5.518LysLeu: 5.518 ± 0.572
2.897LysMet: 2.897 ± 0.478
3.104LysAsn: 3.104 ± 0.513
2.138LysPro: 2.138 ± 0.48
3.104LysGln: 3.104 ± 0.539
3.518LysArg: 3.518 ± 0.555
5.173LysSer: 5.173 ± 0.622
3.035LysThr: 3.035 ± 0.527
4.69LysVal: 4.69 ± 0.551
1.173LysTrp: 1.173 ± 0.292
2.276LysTyr: 2.276 ± 0.336
0.0LysXaa: 0.0 ± 0.0
Leu
5.449LeuAla: 5.449 ± 0.71
0.966LeuCys: 0.966 ± 0.283
3.587LeuAsp: 3.587 ± 0.426
3.863LeuGlu: 3.863 ± 0.494
2.414LeuPhe: 2.414 ± 0.344
5.656LeuGly: 5.656 ± 0.516
1.311LeuHis: 1.311 ± 0.298
4.552LeuIle: 4.552 ± 0.585
4.69LeuLys: 4.69 ± 0.674
5.104LeuLeu: 5.104 ± 0.663
2.0LeuMet: 2.0 ± 0.328
3.794LeuAsn: 3.794 ± 0.718
2.897LeuPro: 2.897 ± 0.484
2.966LeuGln: 2.966 ± 0.491
4.759LeuArg: 4.759 ± 0.51
4.69LeuSer: 4.69 ± 0.525
4.345LeuThr: 4.345 ± 0.552
4.897LeuVal: 4.897 ± 0.547
1.793LeuTrp: 1.793 ± 0.269
2.345LeuTyr: 2.345 ± 0.415
0.0LeuXaa: 0.0 ± 0.0
Met
2.966MetAla: 2.966 ± 0.448
0.345MetCys: 0.345 ± 0.153
1.517MetAsp: 1.517 ± 0.435
1.173MetGlu: 1.173 ± 0.251
1.035MetPhe: 1.035 ± 0.272
1.448MetGly: 1.448 ± 0.33
0.828MetHis: 0.828 ± 0.292
1.586MetIle: 1.586 ± 0.349
2.759MetLys: 2.759 ± 0.459
2.138MetLeu: 2.138 ± 0.339
1.311MetMet: 1.311 ± 0.312
2.0MetAsn: 2.0 ± 0.336
1.862MetPro: 1.862 ± 0.389
1.311MetGln: 1.311 ± 0.304
1.931MetArg: 1.931 ± 0.341
2.414MetSer: 2.414 ± 0.469
1.448MetThr: 1.448 ± 0.353
1.793MetVal: 1.793 ± 0.367
0.483MetTrp: 0.483 ± 0.169
1.242MetTyr: 1.242 ± 0.224
0.0MetXaa: 0.0 ± 0.0
Asn
4.621AsnAla: 4.621 ± 0.591
0.414AsnCys: 0.414 ± 0.172
3.449AsnAsp: 3.449 ± 0.612
2.69AsnGlu: 2.69 ± 0.421
1.035AsnPhe: 1.035 ± 0.316
4.414AsnGly: 4.414 ± 0.521
1.517AsnHis: 1.517 ± 0.321
3.104AsnIle: 3.104 ± 0.508
3.311AsnLys: 3.311 ± 0.461
3.587AsnLeu: 3.587 ± 0.479
1.311AsnMet: 1.311 ± 0.345
2.0AsnAsn: 2.0 ± 0.416
1.931AsnPro: 1.931 ± 0.346
1.311AsnGln: 1.311 ± 0.244
2.0AsnArg: 2.0 ± 0.311
3.035AsnSer: 3.035 ± 0.545
2.69AsnThr: 2.69 ± 0.483
3.242AsnVal: 3.242 ± 0.535
0.621AsnTrp: 0.621 ± 0.203
1.586AsnTyr: 1.586 ± 0.327
0.0AsnXaa: 0.0 ± 0.0
Pro
2.897ProAla: 2.897 ± 0.522
0.828ProCys: 0.828 ± 0.226
2.897ProAsp: 2.897 ± 0.462
2.759ProGlu: 2.759 ± 0.62
0.897ProPhe: 0.897 ± 0.237
1.793ProGly: 1.793 ± 0.362
0.621ProHis: 0.621 ± 0.213
1.793ProIle: 1.793 ± 0.294
1.862ProLys: 1.862 ± 0.395
2.069ProLeu: 2.069 ± 0.404
0.552ProMet: 0.552 ± 0.189
1.173ProAsn: 1.173 ± 0.297
0.966ProPro: 0.966 ± 0.311
1.448ProGln: 1.448 ± 0.408
1.311ProArg: 1.311 ± 0.309
1.724ProSer: 1.724 ± 0.372
2.069ProThr: 2.069 ± 0.434
2.966ProVal: 2.966 ± 0.522
0.414ProTrp: 0.414 ± 0.196
1.862ProTyr: 1.862 ± 0.352
0.069ProXaa: 0.069 ± 0.066
Gln
2.552GlnAla: 2.552 ± 0.485
0.621GlnCys: 0.621 ± 0.223
1.793GlnAsp: 1.793 ± 0.399
2.828GlnGlu: 2.828 ± 0.376
1.586GlnPhe: 1.586 ± 0.37
1.448GlnGly: 1.448 ± 0.392
1.035GlnHis: 1.035 ± 0.287
2.483GlnIle: 2.483 ± 0.434
2.69GlnLys: 2.69 ± 0.462
3.932GlnLeu: 3.932 ± 0.612
1.517GlnMet: 1.517 ± 0.37
1.035GlnAsn: 1.035 ± 0.278
1.586GlnPro: 1.586 ± 0.337
2.414GlnGln: 2.414 ± 0.641
2.138GlnArg: 2.138 ± 0.421
2.759GlnSer: 2.759 ± 0.471
2.207GlnThr: 2.207 ± 0.498
2.621GlnVal: 2.621 ± 0.458
0.552GlnTrp: 0.552 ± 0.212
1.586GlnTyr: 1.586 ± 0.251
0.0GlnXaa: 0.0 ± 0.0
Arg
4.139ArgAla: 4.139 ± 0.548
1.448ArgCys: 1.448 ± 0.405
2.759ArgAsp: 2.759 ± 0.403
3.449ArgGlu: 3.449 ± 0.555
1.517ArgPhe: 1.517 ± 0.319
3.311ArgGly: 3.311 ± 0.52
0.621ArgHis: 0.621 ± 0.185
3.725ArgIle: 3.725 ± 0.544
4.276ArgLys: 4.276 ± 0.585
3.932ArgLeu: 3.932 ± 0.477
1.724ArgMet: 1.724 ± 0.381
3.311ArgAsn: 3.311 ± 0.534
1.38ArgPro: 1.38 ± 0.316
2.207ArgGln: 2.207 ± 0.438
2.552ArgArg: 2.552 ± 0.45
2.483ArgSer: 2.483 ± 0.394
1.793ArgThr: 1.793 ± 0.439
3.311ArgVal: 3.311 ± 0.482
0.552ArgTrp: 0.552 ± 0.219
2.828ArgTyr: 2.828 ± 0.399
0.0ArgXaa: 0.0 ± 0.0
Ser
5.587SerAla: 5.587 ± 0.772
0.897SerCys: 0.897 ± 0.252
4.001SerAsp: 4.001 ± 0.548
3.863SerGlu: 3.863 ± 0.578
2.897SerPhe: 2.897 ± 0.454
5.932SerGly: 5.932 ± 0.676
0.897SerHis: 0.897 ± 0.216
3.656SerIle: 3.656 ± 0.495
3.725SerLys: 3.725 ± 0.593
5.932SerLeu: 5.932 ± 0.654
1.38SerMet: 1.38 ± 0.278
2.207SerAsn: 2.207 ± 0.342
2.414SerPro: 2.414 ± 0.365
2.414SerGln: 2.414 ± 0.5
2.828SerArg: 2.828 ± 0.411
3.587SerSer: 3.587 ± 0.464
4.07SerThr: 4.07 ± 0.639
3.794SerVal: 3.794 ± 0.543
1.311SerTrp: 1.311 ± 0.291
2.0SerTyr: 2.0 ± 0.333
0.0SerXaa: 0.0 ± 0.0
Thr
4.897ThrAla: 4.897 ± 0.863
0.552ThrCys: 0.552 ± 0.169
2.828ThrAsp: 2.828 ± 0.548
4.001ThrGlu: 4.001 ± 0.487
1.793ThrPhe: 1.793 ± 0.484
5.242ThrGly: 5.242 ± 0.626
0.552ThrHis: 0.552 ± 0.17
3.242ThrIle: 3.242 ± 0.509
3.311ThrLys: 3.311 ± 0.504
3.794ThrLeu: 3.794 ± 0.713
1.517ThrMet: 1.517 ± 0.284
2.552ThrAsn: 2.552 ± 0.474
3.035ThrPro: 3.035 ± 0.506
1.931ThrGln: 1.931 ± 0.341
2.69ThrArg: 2.69 ± 0.491
2.828ThrSer: 2.828 ± 0.646
3.518ThrThr: 3.518 ± 0.654
2.897ThrVal: 2.897 ± 0.577
0.759ThrTrp: 0.759 ± 0.306
1.793ThrTyr: 1.793 ± 0.341
0.0ThrXaa: 0.0 ± 0.0
Val
5.656ValAla: 5.656 ± 0.709
0.966ValCys: 0.966 ± 0.297
4.207ValAsp: 4.207 ± 0.685
4.276ValGlu: 4.276 ± 0.578
2.483ValPhe: 2.483 ± 0.474
4.276ValGly: 4.276 ± 0.626
1.104ValHis: 1.104 ± 0.304
5.449ValIle: 5.449 ± 0.66
4.483ValLys: 4.483 ± 0.575
4.207ValLeu: 4.207 ± 0.592
2.069ValMet: 2.069 ± 0.32
4.139ValAsn: 4.139 ± 0.571
1.38ValPro: 1.38 ± 0.31
2.483ValGln: 2.483 ± 0.404
2.828ValArg: 2.828 ± 0.391
5.035ValSer: 5.035 ± 0.594
3.863ValThr: 3.863 ± 0.659
4.207ValVal: 4.207 ± 0.632
1.311ValTrp: 1.311 ± 0.297
2.414ValTyr: 2.414 ± 0.314
0.0ValXaa: 0.0 ± 0.0
Trp
0.897TrpAla: 0.897 ± 0.219
0.207TrpCys: 0.207 ± 0.12
0.897TrpAsp: 0.897 ± 0.234
0.828TrpGlu: 0.828 ± 0.219
0.69TrpPhe: 0.69 ± 0.236
0.276TrpGly: 0.276 ± 0.136
0.828TrpHis: 0.828 ± 0.262
1.035TrpIle: 1.035 ± 0.249
1.173TrpLys: 1.173 ± 0.293
1.242TrpLeu: 1.242 ± 0.347
0.414TrpMet: 0.414 ± 0.187
1.035TrpAsn: 1.035 ± 0.281
0.759TrpPro: 0.759 ± 0.227
0.621TrpGln: 0.621 ± 0.224
1.242TrpArg: 1.242 ± 0.29
0.966TrpSer: 0.966 ± 0.252
0.828TrpThr: 0.828 ± 0.222
1.38TrpVal: 1.38 ± 0.285
0.138TrpTrp: 0.138 ± 0.093
0.414TrpTyr: 0.414 ± 0.146
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.897TyrAla: 2.897 ± 0.327
0.621TyrCys: 0.621 ± 0.187
3.035TyrAsp: 3.035 ± 0.51
1.931TyrGlu: 1.931 ± 0.332
1.38TyrPhe: 1.38 ± 0.339
3.311TyrGly: 3.311 ± 0.542
0.69TyrHis: 0.69 ± 0.209
2.69TyrIle: 2.69 ± 0.478
1.862TyrLys: 1.862 ± 0.402
2.345TyrLeu: 2.345 ± 0.473
0.69TyrMet: 0.69 ± 0.177
1.517TyrAsn: 1.517 ± 0.272
1.173TyrPro: 1.173 ± 0.269
1.655TyrGln: 1.655 ± 0.303
1.724TyrArg: 1.724 ± 0.269
3.173TyrSer: 3.173 ± 0.489
2.207TyrThr: 2.207 ± 0.536
2.483TyrVal: 2.483 ± 0.539
1.035TyrTrp: 1.035 ± 0.272
1.104TyrTyr: 1.104 ± 0.282
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.069XaaAsp: 0.069 ± 0.066
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.069XaaIle: 0.069 ± 0.072
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 84 proteins (14499 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski