Amino acid dipepetide frequency for Lomentospora prolificans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.719AlaAla: 9.719 ± 0.08	1.042AlaCys: 1.042 ± 0.017	4.565AlaAsp: 4.565 ± 0.035	5.446AlaGlu: 5.446 ± 0.046	3.21AlaPhe: 3.21 ± 0.033	6.13AlaGly: 6.13 ± 0.046	1.738AlaHis: 1.738 ± 0.022	4.368AlaIle: 4.368 ± 0.032	4.371AlaLys: 4.371 ± 0.038	7.866AlaLeu: 7.866 ± 0.053	2.063AlaMet: 2.063 ± 0.02	3.062AlaAsn: 3.062 ± 0.028	5.054AlaPro: 5.054 ± 0.045	3.351AlaGln: 3.351 ± 0.037	5.111AlaArg: 5.111 ± 0.038	7.359AlaSer: 7.359 ± 0.052	5.475AlaThr: 5.475 ± 0.04	5.626AlaVal: 5.626 ± 0.043	1.165AlaTrp: 1.165 ± 0.017	2.169AlaTyr: 2.169 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.925CysAla: 0.925 ± 0.019	0.226CysCys: 0.226 ± 0.008	0.651CysAsp: 0.651 ± 0.012	0.6CysGlu: 0.6 ± 0.014	0.508CysPhe: 0.508 ± 0.011	0.95CysGly: 0.95 ± 0.018	0.312CysHis: 0.312 ± 0.009	0.687CysIle: 0.687 ± 0.013	0.507CysLys: 0.507 ± 0.01	1.173CysLeu: 1.173 ± 0.019	0.245CysMet: 0.245 ± 0.008	0.413CysAsn: 0.413 ± 0.011	0.653CysPro: 0.653 ± 0.014	0.415CysGln: 0.415 ± 0.011	0.711CysArg: 0.711 ± 0.013	0.832CysSer: 0.832 ± 0.015	0.667CysThr: 0.667 ± 0.014	0.795CysVal: 0.795 ± 0.015	0.193CysTrp: 0.193 ± 0.006	0.339CysTyr: 0.339 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.936AspAla: 4.936 ± 0.038	0.599AspCys: 0.599 ± 0.013	4.608AspAsp: 4.608 ± 0.052	4.697AspGlu: 4.697 ± 0.046	2.258AspPhe: 2.258 ± 0.025	4.402AspGly: 4.402 ± 0.039	1.184AspHis: 1.184 ± 0.018	3.071AspIle: 3.071 ± 0.028	2.482AspLys: 2.482 ± 0.028	5.123AspLeu: 5.123 ± 0.036	1.295AspMet: 1.295 ± 0.018	1.841AspAsn: 1.841 ± 0.022	3.527AspPro: 3.527 ± 0.026	1.749AspGln: 1.749 ± 0.025	3.121AspArg: 3.121 ± 0.036	4.149AspSer: 4.149 ± 0.037	2.878AspThr: 2.878 ± 0.028	3.848AspVal: 3.848 ± 0.036	0.882AspTrp: 0.882 ± 0.018	1.597AspTyr: 1.597 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.698GluAla: 5.698 ± 0.04	0.641GluCys: 0.641 ± 0.012	4.329GluAsp: 4.329 ± 0.042	5.696GluGlu: 5.696 ± 0.064	1.956GluPhe: 1.956 ± 0.021	4.016GluGly: 4.016 ± 0.032	1.274GluHis: 1.274 ± 0.018	3.008GluIle: 3.008 ± 0.029	3.764GluLys: 3.764 ± 0.039	5.295GluLeu: 5.295 ± 0.044	1.475GluMet: 1.475 ± 0.021	2.282GluAsn: 2.282 ± 0.023	3.049GluPro: 3.049 ± 0.04	2.306GluGln: 2.306 ± 0.028	3.974GluArg: 3.974 ± 0.037	4.197GluSer: 4.197 ± 0.031	3.44GluThr: 3.44 ± 0.033	3.721GluVal: 3.721 ± 0.032	0.87GluTrp: 0.87 ± 0.014	1.668GluTyr: 1.668 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.042PheAla: 3.042 ± 0.031	0.533PheCys: 0.533 ± 0.012	2.259PheAsp: 2.259 ± 0.025	2.132PheGlu: 2.132 ± 0.022	1.62PhePhe: 1.62 ± 0.025	2.893PheGly: 2.893 ± 0.037	0.861PheHis: 0.861 ± 0.015	1.837PheIle: 1.837 ± 0.023	1.57PheLys: 1.57 ± 0.024	3.385PheLeu: 3.385 ± 0.036	0.777PheMet: 0.777 ± 0.013	1.434PheAsn: 1.434 ± 0.019	1.929PhePro: 1.929 ± 0.024	1.308PheGln: 1.308 ± 0.02	2.006PheArg: 2.006 ± 0.023	2.922PheSer: 2.922 ± 0.03	2.143PheThr: 2.143 ± 0.029	2.446PheVal: 2.446 ± 0.027	0.632PheTrp: 0.632 ± 0.013	1.108PheTyr: 1.108 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.742GlyAla: 5.742 ± 0.046	0.869GlyCys: 0.869 ± 0.018	3.941GlyAsp: 3.941 ± 0.039	3.918GlyGlu: 3.918 ± 0.033	2.805GlyPhe: 2.805 ± 0.03	6.289GlyGly: 6.289 ± 0.073	1.659GlyHis: 1.659 ± 0.022	3.584GlyIle: 3.584 ± 0.032	3.499GlyLys: 3.499 ± 0.032	6.127GlyLeu: 6.127 ± 0.044	1.591GlyMet: 1.591 ± 0.022	2.62GlyAsn: 2.62 ± 0.029	3.63GlyPro: 3.63 ± 0.037	2.525GlyGln: 2.525 ± 0.025	4.296GlyArg: 4.296 ± 0.035	5.836GlySer: 5.836 ± 0.048	4.06GlyThr: 4.06 ± 0.034	4.613GlyVal: 4.613 ± 0.039	1.178GlyTrp: 1.178 ± 0.018	2.138GlyTyr: 2.138 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.759HisAla: 1.759 ± 0.024	0.302HisCys: 0.302 ± 0.008	1.251HisAsp: 1.251 ± 0.019	1.235HisGlu: 1.235 ± 0.019	0.873HisPhe: 0.873 ± 0.012	1.696HisGly: 1.696 ± 0.024	0.837HisHis: 0.837 ± 0.019	1.197HisIle: 1.197 ± 0.017	0.874HisLys: 0.874 ± 0.013	2.124HisLeu: 2.124 ± 0.023	0.471HisMet: 0.471 ± 0.011	0.78HisAsn: 0.78 ± 0.015	1.637HisPro: 1.637 ± 0.019	0.923HisGln: 0.923 ± 0.016	1.476HisArg: 1.476 ± 0.021	1.689HisSer: 1.689 ± 0.02	1.198HisThr: 1.198 ± 0.018	1.392HisVal: 1.392 ± 0.018	0.314HisTrp: 0.314 ± 0.01	0.685HisTyr: 0.685 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.158IleAla: 4.158 ± 0.035	0.698IleCys: 0.698 ± 0.013	2.903IleAsp: 2.903 ± 0.026	2.857IleGlu: 2.857 ± 0.024	1.971IlePhe: 1.971 ± 0.024	3.166IleGly: 3.166 ± 0.031	1.164IleHis: 1.164 ± 0.015	2.551IleIle: 2.551 ± 0.028	2.205IleLys: 2.205 ± 0.026	4.609IleLeu: 4.609 ± 0.036	1.047IleMet: 1.047 ± 0.016	1.759IleAsn: 1.759 ± 0.021	3.084IlePro: 3.084 ± 0.027	1.843IleGln: 1.843 ± 0.022	2.883IleArg: 2.883 ± 0.025	3.754IleSer: 3.754 ± 0.033	2.85IleThr: 2.85 ± 0.028	3.279IleVal: 3.279 ± 0.032	0.715IleTrp: 0.715 ± 0.014	1.371IleTyr: 1.371 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.523LysAla: 4.523 ± 0.041	0.483LysCys: 0.483 ± 0.01	2.862LysAsp: 2.862 ± 0.032	3.396LysGlu: 3.396 ± 0.039	1.528LysPhe: 1.528 ± 0.018	3.043LysGly: 3.043 ± 0.03	1.049LysHis: 1.049 ± 0.015	2.2LysIle: 2.2 ± 0.026	3.499LysLys: 3.499 ± 0.055	4.163LysLeu: 4.163 ± 0.035	1.014LysMet: 1.014 ± 0.017	1.697LysAsn: 1.697 ± 0.019	2.814LysPro: 2.814 ± 0.028	1.722LysGln: 1.722 ± 0.021	3.398LysArg: 3.398 ± 0.035	3.456LysSer: 3.456 ± 0.035	2.73LysThr: 2.73 ± 0.026	2.987LysVal: 2.987 ± 0.033	0.693LysTrp: 0.693 ± 0.014	1.361LysTyr: 1.361 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	8.169LeuAla: 8.169 ± 0.054	1.161LeuCys: 1.161 ± 0.017	5.272LeuAsp: 5.272 ± 0.038	5.471LeuGlu: 5.471 ± 0.037	3.265LeuPhe: 3.265 ± 0.034	6.06LeuGly: 6.06 ± 0.039	2.095LeuHis: 2.095 ± 0.024	3.91LeuIle: 3.91 ± 0.039	4.169LeuLys: 4.169 ± 0.04	8.207LeuLeu: 8.207 ± 0.064	1.754LeuMet: 1.754 ± 0.023	3.03LeuAsn: 3.03 ± 0.031	5.386LeuPro: 5.386 ± 0.043	3.479LeuGln: 3.479 ± 0.037	5.768LeuArg: 5.768 ± 0.04	7.097LeuSer: 7.097 ± 0.053	4.868LeuThr: 4.868 ± 0.039	5.624LeuVal: 5.624 ± 0.044	1.171LeuTrp: 1.171 ± 0.017	2.325LeuTyr: 2.325 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.334MetAla: 2.334 ± 0.024	0.231MetCys: 0.231 ± 0.007	1.27MetAsp: 1.27 ± 0.017	1.265MetGlu: 1.265 ± 0.02	0.727MetPhe: 0.727 ± 0.013	1.513MetGly: 1.513 ± 0.02	0.454MetHis: 0.454 ± 0.011	0.961MetIle: 0.961 ± 0.014	1.019MetLys: 1.019 ± 0.016	1.779MetLeu: 1.779 ± 0.02	0.581MetMet: 0.581 ± 0.014	0.778MetAsn: 0.778 ± 0.014	1.261MetPro: 1.261 ± 0.02	0.797MetGln: 0.797 ± 0.015	1.285MetArg: 1.285 ± 0.017	1.805MetSer: 1.805 ± 0.022	1.307MetThr: 1.307 ± 0.018	1.339MetVal: 1.339 ± 0.018	0.266MetTrp: 0.266 ± 0.008	0.534MetTyr: 0.534 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.056AsnAla: 3.056 ± 0.031	0.43AsnCys: 0.43 ± 0.012	1.884AsnAsp: 1.884 ± 0.019	1.96AsnGlu: 1.96 ± 0.021	1.321AsnPhe: 1.321 ± 0.017	3.041AsnGly: 3.041 ± 0.032	0.821AsnHis: 0.821 ± 0.013	1.976AsnIle: 1.976 ± 0.019	1.531AsnLys: 1.531 ± 0.02	3.228AsnLeu: 3.228 ± 0.031	0.823AsnMet: 0.823 ± 0.013	1.466AsnAsn: 1.466 ± 0.029	2.565AsnPro: 2.565 ± 0.024	1.273AsnGln: 1.273 ± 0.019	1.979AsnArg: 1.979 ± 0.023	2.628AsnSer: 2.628 ± 0.026	2.036AsnThr: 2.036 ± 0.025	2.262AsnVal: 2.262 ± 0.024	0.547AsnTrp: 0.547 ± 0.009	1.032AsnTyr: 1.032 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.629ProAla: 5.629 ± 0.05	0.501ProCys: 0.501 ± 0.009	3.331ProAsp: 3.331 ± 0.027	4.049ProGlu: 4.049 ± 0.037	2.053ProPhe: 2.053 ± 0.024	4.217ProGly: 4.217 ± 0.041	1.353ProHis: 1.353 ± 0.021	2.652ProIle: 2.652 ± 0.022	2.719ProLys: 2.719 ± 0.028	4.737ProLeu: 4.737 ± 0.036	1.085ProMet: 1.085 ± 0.021	2.278ProAsn: 2.278 ± 0.027	5.396ProPro: 5.396 ± 0.071	2.407ProGln: 2.407 ± 0.032	3.545ProArg: 3.545 ± 0.042	5.921ProSer: 5.921 ± 0.05	4.271ProThr: 4.271 ± 0.039	3.695ProVal: 3.695 ± 0.036	0.737ProTrp: 0.737 ± 0.012	1.474ProTyr: 1.474 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.457GlnAla: 3.457 ± 0.037	0.433GlnCys: 0.433 ± 0.011	1.93GlnAsp: 1.93 ± 0.021	2.273GlnGlu: 2.273 ± 0.027	1.269GlnPhe: 1.269 ± 0.02	2.415GlnGly: 2.415 ± 0.024	0.975GlnHis: 0.975 ± 0.018	1.753GlnIle: 1.753 ± 0.021	1.856GlnLys: 1.856 ± 0.025	3.246GlnLeu: 3.246 ± 0.032	0.821GlnMet: 0.821 ± 0.016	1.407GlnAsn: 1.407 ± 0.02	2.478GlnPro: 2.478 ± 0.031	2.275GlnGln: 2.275 ± 0.052	2.505GlnArg: 2.505 ± 0.027	2.819GlnSer: 2.819 ± 0.029	2.128GlnThr: 2.128 ± 0.024	2.18GlnVal: 2.18 ± 0.026	0.523GlnTrp: 0.523 ± 0.012	1.082GlnTyr: 1.082 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.903ArgAla: 4.903 ± 0.035	0.696ArgCys: 0.696 ± 0.015	3.567ArgAsp: 3.567 ± 0.043	3.98ArgGlu: 3.98 ± 0.035	2.106ArgPhe: 2.106 ± 0.023	3.888ArgGly: 3.888 ± 0.037	1.532ArgHis: 1.532 ± 0.02	2.925ArgIle: 2.925 ± 0.026	3.474ArgLys: 3.474 ± 0.036	5.474ArgLeu: 5.474 ± 0.044	1.323ArgMet: 1.323 ± 0.018	2.217ArgAsn: 2.217 ± 0.025	3.672ArgPro: 3.672 ± 0.037	2.553ArgGln: 2.553 ± 0.028	5.3ArgArg: 5.3 ± 0.054	4.697ArgSer: 4.697 ± 0.04	3.326ArgThr: 3.326 ± 0.034	3.538ArgVal: 3.538 ± 0.032	0.923ArgTrp: 0.923 ± 0.015	1.648ArgTyr: 1.648 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	6.699SerAla: 6.699 ± 0.045	0.817SerCys: 0.817 ± 0.015	4.191SerAsp: 4.191 ± 0.035	4.093SerGlu: 4.093 ± 0.037	2.953SerPhe: 2.953 ± 0.027	5.733SerGly: 5.733 ± 0.04	1.812SerHis: 1.812 ± 0.024	3.836SerIle: 3.836 ± 0.03	3.572SerLys: 3.572 ± 0.034	6.974SerLeu: 6.974 ± 0.046	1.653SerMet: 1.653 ± 0.022	2.835SerAsn: 2.835 ± 0.024	5.577SerPro: 5.577 ± 0.057	3.09SerGln: 3.09 ± 0.034	5.088SerArg: 5.088 ± 0.045	8.123SerSer: 8.123 ± 0.079	5.277SerThr: 5.277 ± 0.043	4.545SerVal: 4.545 ± 0.031	1.094SerTrp: 1.094 ± 0.017	1.971SerTyr: 1.971 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.229ThrAla: 5.229 ± 0.038	0.734ThrCys: 0.734 ± 0.015	2.849ThrAsp: 2.849 ± 0.025	3.171ThrGlu: 3.171 ± 0.029	2.207ThrPhe: 2.207 ± 0.021	4.21ThrGly: 4.21 ± 0.036	1.218ThrHis: 1.218 ± 0.016	3.084ThrIle: 3.084 ± 0.029	2.639ThrLys: 2.639 ± 0.031	5.19ThrLeu: 5.19 ± 0.033	1.211ThrMet: 1.211 ± 0.015	2.016ThrAsn: 2.016 ± 0.022	4.499ThrPro: 4.499 ± 0.045	2.004ThrGln: 2.004 ± 0.023	3.192ThrArg: 3.192 ± 0.03	5.066ThrSer: 5.066 ± 0.041	4.169ThrThr: 4.169 ± 0.038	3.811ThrVal: 3.811 ± 0.032	0.826ThrTrp: 0.826 ± 0.014	1.572ThrTyr: 1.572 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.623ValAla: 5.623 ± 0.045	0.808ValCys: 0.808 ± 0.015	3.999ValAsp: 3.999 ± 0.035	4.046ValGlu: 4.046 ± 0.032	2.445ValPhe: 2.445 ± 0.024	4.236ValGly: 4.236 ± 0.04	1.322ValHis: 1.322 ± 0.017	3.121ValIle: 3.121 ± 0.032	2.979ValLys: 2.979 ± 0.03	5.67ValLeu: 5.67 ± 0.043	1.347ValMet: 1.347 ± 0.017	2.264ValAsn: 2.264 ± 0.023	3.721ValPro: 3.721 ± 0.03	2.263ValGln: 2.263 ± 0.025	3.521ValArg: 3.521 ± 0.028	4.679ValSer: 4.679 ± 0.04	3.644ValThr: 3.644 ± 0.037	4.549ValVal: 4.549 ± 0.036	0.879ValTrp: 0.879 ± 0.016	1.744ValTyr: 1.744 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.16TrpAla: 1.16 ± 0.017	0.193TrpCys: 0.193 ± 0.006	0.907TrpAsp: 0.907 ± 0.016	0.848TrpGlu: 0.848 ± 0.015	0.556TrpPhe: 0.556 ± 0.012	0.94TrpGly: 0.94 ± 0.017	0.345TrpHis: 0.345 ± 0.01	0.756TrpIle: 0.756 ± 0.014	0.787TrpLys: 0.787 ± 0.015	1.306TrpLeu: 1.306 ± 0.017	0.34TrpMet: 0.34 ± 0.008	0.606TrpAsn: 0.606 ± 0.011	0.613TrpPro: 0.613 ± 0.012	0.52TrpGln: 0.52 ± 0.01	0.939TrpArg: 0.939 ± 0.017	0.976TrpSer: 0.976 ± 0.016	0.869TrpThr: 0.869 ± 0.014	0.942TrpVal: 0.942 ± 0.016	0.277TrpTrp: 0.277 ± 0.009	0.439TrpTyr: 0.439 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.127TyrAla: 2.127 ± 0.025	0.409TyrCys: 0.409 ± 0.011	1.676TyrAsp: 1.676 ± 0.022	1.525TyrGlu: 1.525 ± 0.022	1.203TyrPhe: 1.203 ± 0.018	2.084TyrGly: 2.084 ± 0.027	0.709TyrHis: 0.709 ± 0.013	1.389TyrIle: 1.389 ± 0.021	1.105TyrLys: 1.105 ± 0.016	2.607TyrLeu: 2.607 ± 0.029	0.589TyrMet: 0.589 ± 0.012	1.073TyrAsn: 1.073 ± 0.016	1.505TyrPro: 1.505 ± 0.02	1.021TyrGln: 1.021 ± 0.019	1.643TyrArg: 1.643 ± 0.021	1.926TyrSer: 1.926 ± 0.02	1.56TyrThr: 1.56 ± 0.019	1.671TyrVal: 1.671 ± 0.021	0.434TyrTrp: 0.434 ± 0.01	0.913TyrTyr: 0.913 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8533 proteins (4365240 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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