Amino acid dipepetide frequency for Mangrovibacterium marinum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.181AlaAla: 6.181 ± 0.095	0.855AlaCys: 0.855 ± 0.026	4.845AlaAsp: 4.845 ± 0.067	5.173AlaGlu: 5.173 ± 0.073	3.564AlaPhe: 3.564 ± 0.058	5.747AlaGly: 5.747 ± 0.078	1.277AlaHis: 1.277 ± 0.035	5.163AlaIle: 5.163 ± 0.075	4.302AlaLys: 4.302 ± 0.069	6.825AlaLeu: 6.825 ± 0.092	1.89AlaMet: 1.89 ± 0.043	3.502AlaAsn: 3.502 ± 0.061	2.341AlaPro: 2.341 ± 0.049	3.026AlaGln: 3.026 ± 0.057	3.127AlaArg: 3.127 ± 0.051	4.645AlaSer: 4.645 ± 0.073	3.857AlaThr: 3.857 ± 0.092	5.019AlaVal: 5.019 ± 0.074	0.962AlaTrp: 0.962 ± 0.026	2.896AlaTyr: 2.896 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.62CysAla: 0.62 ± 0.024	0.156CysCys: 0.156 ± 0.011	0.542CysAsp: 0.542 ± 0.026	0.554CysGlu: 0.554 ± 0.029	0.489CysPhe: 0.489 ± 0.018	0.798CysGly: 0.798 ± 0.032	0.236CysHis: 0.236 ± 0.018	0.545CysIle: 0.545 ± 0.022	0.459CysLys: 0.459 ± 0.017	0.878CysLeu: 0.878 ± 0.028	0.215CysMet: 0.215 ± 0.013	0.43CysAsn: 0.43 ± 0.018	0.496CysPro: 0.496 ± 0.037	0.348CysGln: 0.348 ± 0.016	0.465CysArg: 0.465 ± 0.021	0.666CysSer: 0.666 ± 0.033	0.527CysThr: 0.527 ± 0.022	0.493CysVal: 0.493 ± 0.024	0.14CysTrp: 0.14 ± 0.011	0.361CysTyr: 0.361 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.126AspAla: 4.126 ± 0.067	0.581AspCys: 0.581 ± 0.031	3.279AspAsp: 3.279 ± 0.071	4.333AspGlu: 4.333 ± 0.065	3.361AspPhe: 3.361 ± 0.052	4.435AspGly: 4.435 ± 0.075	1.076AspHis: 1.076 ± 0.028	3.585AspIle: 3.585 ± 0.055	3.22AspLys: 3.22 ± 0.054	5.657AspLeu: 5.657 ± 0.072	1.28AspMet: 1.28 ± 0.032	2.596AspAsn: 2.596 ± 0.058	2.371AspPro: 2.371 ± 0.053	2.435AspGln: 2.435 ± 0.048	2.401AspArg: 2.401 ± 0.042	3.168AspSer: 3.168 ± 0.058	2.243AspThr: 2.243 ± 0.046	3.601AspVal: 3.601 ± 0.065	0.944AspTrp: 0.944 ± 0.03	2.877AspTyr: 2.877 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	4.988GluAla: 4.988 ± 0.079	0.429GluCys: 0.429 ± 0.018	3.134GluAsp: 3.134 ± 0.058	4.327GluGlu: 4.327 ± 0.068	2.693GluPhe: 2.693 ± 0.047	3.963GluGly: 3.963 ± 0.055	1.177GluHis: 1.177 ± 0.032	4.754GluIle: 4.754 ± 0.073	4.953GluLys: 4.953 ± 0.076	7.09GluLeu: 7.09 ± 0.093	1.821GluMet: 1.821 ± 0.038	3.703GluAsn: 3.703 ± 0.063	1.897GluPro: 1.897 ± 0.041	3.178GluGln: 3.178 ± 0.065	2.865GluArg: 2.865 ± 0.046	3.514GluSer: 3.514 ± 0.047	3.257GluThr: 3.257 ± 0.052	4.056GluVal: 4.056 ± 0.059	0.738GluTrp: 0.738 ± 0.022	2.34GluTyr: 2.34 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	3.403PheAla: 3.403 ± 0.053	0.517PheCys: 0.517 ± 0.021	3.112PheAsp: 3.112 ± 0.056	3.032PheGlu: 3.032 ± 0.055	2.378PhePhe: 2.378 ± 0.051	3.354PheGly: 3.354 ± 0.06	0.903PheHis: 0.903 ± 0.029	2.994PheIle: 2.994 ± 0.056	2.668PheLys: 2.668 ± 0.051	4.206PheLeu: 4.206 ± 0.065	1.195PheMet: 1.195 ± 0.031	2.683PheAsn: 2.683 ± 0.048	1.838PhePro: 1.838 ± 0.039	1.649PheGln: 1.649 ± 0.035	2.21PheArg: 2.21 ± 0.04	3.687PheSer: 3.687 ± 0.056	2.737PheThr: 2.737 ± 0.061	3.154PheVal: 3.154 ± 0.055	0.638PheTrp: 0.638 ± 0.023	1.957PheTyr: 1.957 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.759GlyAla: 4.759 ± 0.068	0.69GlyCys: 0.69 ± 0.029	3.847GlyAsp: 3.847 ± 0.072	4.321GlyGlu: 4.321 ± 0.062	3.399GlyPhe: 3.399 ± 0.057	4.886GlyGly: 4.886 ± 0.085	1.228GlyHis: 1.228 ± 0.033	5.111GlyIle: 5.111 ± 0.076	4.749GlyLys: 4.749 ± 0.063	6.298GlyLeu: 6.298 ± 0.084	1.906GlyMet: 1.906 ± 0.04	3.491GlyAsn: 3.491 ± 0.078	1.701GlyPro: 1.701 ± 0.043	2.636GlyGln: 2.636 ± 0.043	2.704GlyArg: 2.704 ± 0.047	4.303GlySer: 4.303 ± 0.087	4.15GlyThr: 4.15 ± 0.087	4.562GlyVal: 4.562 ± 0.072	1.067GlyTrp: 1.067 ± 0.029	3.033GlyTyr: 3.033 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.183HisAla: 1.183 ± 0.034	0.21HisCys: 0.21 ± 0.012	1.008HisAsp: 1.008 ± 0.026	1.13HisGlu: 1.13 ± 0.032	1.199HisPhe: 1.199 ± 0.035	1.247HisGly: 1.247 ± 0.032	0.493HisHis: 0.493 ± 0.022	1.271HisIle: 1.271 ± 0.031	0.978HisLys: 0.978 ± 0.031	1.935HisLeu: 1.935 ± 0.045	0.228HisMet: 0.228 ± 0.013	0.828HisAsn: 0.828 ± 0.027	1.0HisPro: 1.0 ± 0.027	0.837HisGln: 0.837 ± 0.025	0.918HisArg: 0.918 ± 0.027	1.098HisSer: 1.098 ± 0.03	0.84HisThr: 0.84 ± 0.023	0.907HisVal: 0.907 ± 0.027	0.288HisTrp: 0.288 ± 0.016	0.852HisTyr: 0.852 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.334IleAla: 5.334 ± 0.076	0.647IleCys: 0.647 ± 0.024	4.498IleAsp: 4.498 ± 0.07	4.479IleGlu: 4.479 ± 0.063	2.872IlePhe: 2.872 ± 0.05	4.599IleGly: 4.599 ± 0.067	1.338IleHis: 1.338 ± 0.032	4.203IleIle: 4.203 ± 0.076	3.712IleLys: 3.712 ± 0.065	5.899IleLeu: 5.899 ± 0.086	1.262IleMet: 1.262 ± 0.036	3.3IleAsn: 3.3 ± 0.062	3.106IlePro: 3.106 ± 0.055	2.462IleGln: 2.462 ± 0.042	3.406IleArg: 3.406 ± 0.058	4.706IleSer: 4.706 ± 0.06	3.616IleThr: 3.616 ± 0.082	4.129IleVal: 4.129 ± 0.059	0.743IleTrp: 0.743 ± 0.023	2.495IleTyr: 2.495 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.156LysAla: 5.156 ± 0.077	0.391LysCys: 0.391 ± 0.02	3.323LysAsp: 3.323 ± 0.05	4.296LysGlu: 4.296 ± 0.071	2.21LysPhe: 2.21 ± 0.045	3.9LysGly: 3.9 ± 0.059	1.146LysHis: 1.146 ± 0.033	4.32LysIle: 4.32 ± 0.074	4.436LysLys: 4.436 ± 0.067	6.227LysLeu: 6.227 ± 0.085	1.731LysMet: 1.731 ± 0.035	3.31LysAsn: 3.31 ± 0.053	2.398LysPro: 2.398 ± 0.046	2.792LysGln: 2.792 ± 0.054	2.778LysArg: 2.778 ± 0.049	3.676LysSer: 3.676 ± 0.059	3.559LysThr: 3.559 ± 0.052	4.065LysVal: 4.065 ± 0.063	0.726LysTrp: 0.726 ± 0.024	2.57LysTyr: 2.57 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	7.3LeuAla: 7.3 ± 0.08	0.88LeuCys: 0.88 ± 0.031	5.053LeuAsp: 5.053 ± 0.068	5.753LeuGlu: 5.753 ± 0.089	4.84LeuPhe: 4.84 ± 0.077	5.886LeuGly: 5.886 ± 0.085	1.723LeuHis: 1.723 ± 0.038	6.319LeuIle: 6.319 ± 0.094	7.052LeuLys: 7.052 ± 0.086	9.344LeuLeu: 9.344 ± 0.116	2.317LeuMet: 2.317 ± 0.044	4.919LeuAsn: 4.919 ± 0.07	4.058LeuPro: 4.058 ± 0.067	3.553LeuGln: 3.553 ± 0.056	3.935LeuArg: 3.935 ± 0.057	6.635LeuSer: 6.635 ± 0.087	5.328LeuThr: 5.328 ± 0.074	6.151LeuVal: 6.151 ± 0.081	0.996LeuTrp: 0.996 ± 0.029	3.216LeuTyr: 3.216 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.078MetAla: 2.078 ± 0.044	0.15MetCys: 0.15 ± 0.011	1.318MetAsp: 1.318 ± 0.036	1.489MetGlu: 1.489 ± 0.038	0.836MetPhe: 0.836 ± 0.025	1.645MetGly: 1.645 ± 0.041	0.417MetHis: 0.417 ± 0.019	1.481MetIle: 1.481 ± 0.035	2.146MetLys: 2.146 ± 0.041	2.24MetLeu: 2.24 ± 0.043	0.691MetMet: 0.691 ± 0.027	1.408MetAsn: 1.408 ± 0.034	1.049MetPro: 1.049 ± 0.028	0.979MetGln: 0.979 ± 0.024	1.021MetArg: 1.021 ± 0.029	1.363MetSer: 1.363 ± 0.034	1.346MetThr: 1.346 ± 0.032	1.567MetVal: 1.567 ± 0.036	0.209MetTrp: 0.209 ± 0.014	0.724MetTyr: 0.724 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.37AsnAla: 3.37 ± 0.06	0.581AsnCys: 0.581 ± 0.039	2.744AsnAsp: 2.744 ± 0.05	3.196AsnGlu: 3.196 ± 0.047	2.489AsnPhe: 2.489 ± 0.044	3.575AsnGly: 3.575 ± 0.06	0.92AsnHis: 0.92 ± 0.029	3.444AsnIle: 3.444 ± 0.061	3.006AsnLys: 3.006 ± 0.057	4.572AsnLeu: 4.572 ± 0.066	1.266AsnMet: 1.266 ± 0.033	2.505AsnAsn: 2.505 ± 0.057	2.655AsnPro: 2.655 ± 0.043	2.17AsnGln: 2.17 ± 0.039	2.34AsnArg: 2.34 ± 0.043	3.131AsnSer: 3.131 ± 0.057	2.588AsnThr: 2.588 ± 0.048	2.834AsnVal: 2.834 ± 0.056	0.807AsnTrp: 0.807 ± 0.024	2.541AsnTyr: 2.541 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	3.196ProAla: 3.196 ± 0.063	0.268ProCys: 0.268 ± 0.016	2.841ProAsp: 2.841 ± 0.055	3.436ProGlu: 3.436 ± 0.061	1.847ProPhe: 1.847 ± 0.042	2.85ProGly: 2.85 ± 0.05	0.68ProHis: 0.68 ± 0.021	2.22ProIle: 2.22 ± 0.042	2.005ProLys: 2.005 ± 0.041	3.218ProLeu: 3.218 ± 0.049	0.877ProMet: 0.877 ± 0.026	1.827ProAsn: 1.827 ± 0.035	1.008ProPro: 1.008 ± 0.04	1.481ProGln: 1.481 ± 0.034	1.326ProArg: 1.326 ± 0.034	2.148ProSer: 2.148 ± 0.043	2.021ProThr: 2.021 ± 0.061	3.367ProVal: 3.367 ± 0.06	0.46ProTrp: 0.46 ± 0.018	1.49ProTyr: 1.49 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.251GlnAla: 3.251 ± 0.064	0.279GlnCys: 0.279 ± 0.015	1.719GlnAsp: 1.719 ± 0.037	2.363GlnGlu: 2.363 ± 0.05	1.783GlnPhe: 1.783 ± 0.035	2.187GlnGly: 2.187 ± 0.037	0.773GlnHis: 0.773 ± 0.024	2.833GlnIle: 2.833 ± 0.053	2.785GlnLys: 2.785 ± 0.053	4.642GlnLeu: 4.642 ± 0.068	1.063GlnMet: 1.063 ± 0.031	2.05GlnAsn: 2.05 ± 0.045	1.448GlnPro: 1.448 ± 0.038	2.285GlnGln: 2.285 ± 0.062	1.679GlnArg: 1.679 ± 0.038	2.369GlnSer: 2.369 ± 0.082	2.284GlnThr: 2.284 ± 0.045	2.544GlnVal: 2.544 ± 0.04	0.467GlnTrp: 0.467 ± 0.019	1.558GlnTyr: 1.558 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.658ArgAla: 2.658 ± 0.052	0.327ArgCys: 0.327 ± 0.016	2.13ArgAsp: 2.13 ± 0.038	2.996ArgGlu: 2.996 ± 0.052	2.413ArgPhe: 2.413 ± 0.054	2.376ArgGly: 2.376 ± 0.04	0.817ArgHis: 0.817 ± 0.027	3.29ArgIle: 3.29 ± 0.054	3.14ArgLys: 3.14 ± 0.057	4.464ArgLeu: 4.464 ± 0.068	1.259ArgMet: 1.259 ± 0.033	2.339ArgAsn: 2.339 ± 0.039	1.469ArgPro: 1.469 ± 0.036	1.856ArgGln: 1.856 ± 0.041	1.954ArgArg: 1.954 ± 0.046	2.388ArgSer: 2.388 ± 0.047	2.132ArgThr: 2.132 ± 0.044	2.703ArgVal: 2.703 ± 0.045	0.626ArgTrp: 0.626 ± 0.025	1.961ArgTyr: 1.961 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.503SerAla: 4.503 ± 0.069	0.718SerCys: 0.718 ± 0.028	3.536SerAsp: 3.536 ± 0.066	3.629SerGlu: 3.629 ± 0.055	3.462SerPhe: 3.462 ± 0.058	4.988SerGly: 4.988 ± 0.09	1.066SerHis: 1.066 ± 0.03	3.953SerIle: 3.953 ± 0.055	3.437SerLys: 3.437 ± 0.05	6.066SerLeu: 6.066 ± 0.073	1.399SerMet: 1.399 ± 0.035	2.843SerAsn: 2.843 ± 0.055	2.584SerPro: 2.584 ± 0.051	2.284SerGln: 2.284 ± 0.075	2.809SerArg: 2.809 ± 0.053	4.338SerSer: 4.338 ± 0.081	3.281SerThr: 3.281 ± 0.055	4.175SerVal: 4.175 ± 0.054	1.038SerTrp: 1.038 ± 0.031	2.858SerTyr: 2.858 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	4.367ThrAla: 4.367 ± 0.105	0.459ThrCys: 0.459 ± 0.031	3.383ThrAsp: 3.383 ± 0.06	3.096ThrGlu: 3.096 ± 0.05	2.508ThrPhe: 2.508 ± 0.053	4.483ThrGly: 4.483 ± 0.073	0.919ThrHis: 0.919 ± 0.029	4.111ThrIle: 4.111 ± 0.084	2.766ThrLys: 2.766 ± 0.049	4.51ThrLeu: 4.51 ± 0.065	1.076ThrMet: 1.076 ± 0.029	2.702ThrAsn: 2.702 ± 0.056	2.476ThrPro: 2.476 ± 0.061	1.728ThrGln: 1.728 ± 0.038	2.013ThrArg: 2.013 ± 0.045	3.184ThrSer: 3.184 ± 0.051	3.249ThrThr: 3.249 ± 0.081	3.889ThrVal: 3.889 ± 0.111	0.507ThrTrp: 0.507 ± 0.025	2.157ThrTyr: 2.157 ± 0.073	0.0ThrXaa: 0.0 ± 0.0
Val	4.984ValAla: 4.984 ± 0.067	0.687ValCys: 0.687 ± 0.028	4.088ValAsp: 4.088 ± 0.06	4.22ValGlu: 4.22 ± 0.065	3.122ValPhe: 3.122 ± 0.049	4.192ValGly: 4.192 ± 0.062	1.135ValHis: 1.135 ± 0.029	4.237ValIle: 4.237 ± 0.068	4.014ValLys: 4.014 ± 0.066	5.964ValLeu: 5.964 ± 0.08	1.457ValMet: 1.457 ± 0.035	3.4ValAsn: 3.4 ± 0.051	2.59ValPro: 2.59 ± 0.044	2.166ValGln: 2.166 ± 0.045	2.671ValArg: 2.671 ± 0.05	4.485ValSer: 4.485 ± 0.063	3.457ValThr: 3.457 ± 0.112	4.784ValVal: 4.784 ± 0.076	0.777ValTrp: 0.777 ± 0.022	2.469ValTyr: 2.469 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.91TrpAla: 0.91 ± 0.032	0.14TrpCys: 0.14 ± 0.01	0.777TrpAsp: 0.777 ± 0.026	0.815TrpGlu: 0.815 ± 0.027	0.553TrpPhe: 0.553 ± 0.021	0.961TrpGly: 0.961 ± 0.026	0.258TrpHis: 0.258 ± 0.014	0.789TrpIle: 0.789 ± 0.029	0.863TrpLys: 0.863 ± 0.026	1.219TrpLeu: 1.219 ± 0.034	0.369TrpMet: 0.369 ± 0.018	0.739TrpAsn: 0.739 ± 0.027	0.354TrpPro: 0.354 ± 0.018	0.6TrpGln: 0.6 ± 0.022	0.581TrpArg: 0.581 ± 0.024	0.792TrpSer: 0.792 ± 0.027	0.746TrpThr: 0.746 ± 0.038	0.759TrpVal: 0.759 ± 0.025	0.218TrpTrp: 0.218 ± 0.013	0.483TrpTyr: 0.483 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.829TyrAla: 2.829 ± 0.052	0.453TyrCys: 0.453 ± 0.02	2.39TyrAsp: 2.39 ± 0.047	2.24TyrGlu: 2.24 ± 0.039	2.299TyrPhe: 2.299 ± 0.045	2.769TyrGly: 2.769 ± 0.053	0.871TyrHis: 0.871 ± 0.027	2.183TyrIle: 2.183 ± 0.041	2.319TyrLys: 2.319 ± 0.039	4.002TyrLeu: 4.002 ± 0.058	0.853TyrMet: 0.853 ± 0.027	2.161TyrAsn: 2.161 ± 0.046	1.728TyrPro: 1.728 ± 0.041	1.895TyrGln: 1.895 ± 0.043	2.097TyrArg: 2.097 ± 0.043	2.671TyrSer: 2.671 ± 0.048	2.365TyrThr: 2.365 ± 0.076	2.136TyrVal: 2.136 ± 0.038	0.577TyrTrp: 0.577 ± 0.024	1.929TyrTyr: 1.929 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3633 proteins (1323685 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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