Amino acid dipepetide frequency for Ferrimonas sediminum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.788AlaAla: 9.788 ± 0.13	1.228AlaCys: 1.228 ± 0.038	5.729AlaAsp: 5.729 ± 0.07	6.036AlaGlu: 6.036 ± 0.082	3.33AlaPhe: 3.33 ± 0.056	7.363AlaGly: 7.363 ± 0.092	1.906AlaHis: 1.906 ± 0.045	5.666AlaIle: 5.666 ± 0.071	4.0AlaLys: 4.0 ± 0.068	11.79AlaLeu: 11.79 ± 0.132	3.19AlaMet: 3.19 ± 0.055	3.344AlaAsn: 3.344 ± 0.055	3.818AlaPro: 3.818 ± 0.059	4.532AlaGln: 4.532 ± 0.074	5.293AlaArg: 5.293 ± 0.07	6.118AlaSer: 6.118 ± 0.074	4.908AlaThr: 4.908 ± 0.065	6.604AlaVal: 6.604 ± 0.089	1.2AlaTrp: 1.2 ± 0.035	2.345AlaTyr: 2.345 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.984CysAla: 0.984 ± 0.031	0.191CysCys: 0.191 ± 0.013	0.696CysAsp: 0.696 ± 0.024	0.543CysGlu: 0.543 ± 0.023	0.416CysPhe: 0.416 ± 0.019	1.112CysGly: 1.112 ± 0.032	0.705CysHis: 0.705 ± 0.048	0.526CysIle: 0.526 ± 0.018	0.354CysLys: 0.354 ± 0.017	1.127CysLeu: 1.127 ± 0.033	0.228CysMet: 0.228 ± 0.014	0.349CysAsn: 0.349 ± 0.018	0.608CysPro: 0.608 ± 0.032	0.657CysGln: 0.657 ± 0.028	0.749CysArg: 0.749 ± 0.024	0.748CysSer: 0.748 ± 0.026	0.52CysThr: 0.52 ± 0.022	0.654CysVal: 0.654 ± 0.025	0.15CysTrp: 0.15 ± 0.011	0.312CysTyr: 0.312 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.665AspAla: 5.665 ± 0.081	0.628AspCys: 0.628 ± 0.026	3.432AspAsp: 3.432 ± 0.059	3.397AspGlu: 3.397 ± 0.055	2.077AspPhe: 2.077 ± 0.038	4.667AspGly: 4.667 ± 0.089	1.384AspHis: 1.384 ± 0.034	2.854AspIle: 2.854 ± 0.048	2.549AspLys: 2.549 ± 0.047	5.392AspLeu: 5.392 ± 0.066	1.206AspMet: 1.206 ± 0.03	2.331AspAsn: 2.331 ± 0.048	2.604AspPro: 2.604 ± 0.06	2.511AspGln: 2.511 ± 0.045	3.016AspArg: 3.016 ± 0.052	3.6AspSer: 3.6 ± 0.063	3.005AspThr: 3.005 ± 0.053	3.329AspVal: 3.329 ± 0.054	0.918AspTrp: 0.918 ± 0.028	2.004AspTyr: 2.004 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	5.683GluAla: 5.683 ± 0.088	0.553GluCys: 0.553 ± 0.021	2.422GluAsp: 2.422 ± 0.054	3.072GluGlu: 3.072 ± 0.066	2.18GluPhe: 2.18 ± 0.044	3.717GluGly: 3.717 ± 0.058	1.434GluHis: 1.434 ± 0.035	2.827GluIle: 2.827 ± 0.06	2.184GluLys: 2.184 ± 0.043	7.111GluLeu: 7.111 ± 0.1	1.694GluMet: 1.694 ± 0.041	1.574GluAsn: 1.574 ± 0.032	2.316GluPro: 2.316 ± 0.045	4.259GluGln: 4.259 ± 0.075	3.755GluArg: 3.755 ± 0.069	3.074GluSer: 3.074 ± 0.048	2.698GluThr: 2.698 ± 0.047	4.523GluVal: 4.523 ± 0.066	0.644GluTrp: 0.644 ± 0.021	1.498GluTyr: 1.498 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.528PheAla: 3.528 ± 0.062	0.484PheCys: 0.484 ± 0.02	2.764PheAsp: 2.764 ± 0.055	2.324PheGlu: 2.324 ± 0.047	1.421PhePhe: 1.421 ± 0.034	3.222PheGly: 3.222 ± 0.053	0.789PheHis: 0.789 ± 0.025	1.989PheIle: 1.989 ± 0.04	1.414PheLys: 1.414 ± 0.031	3.024PheLeu: 3.024 ± 0.052	0.934PheMet: 0.934 ± 0.027	1.58PheAsn: 1.58 ± 0.036	1.305PhePro: 1.305 ± 0.03	1.239PheGln: 1.239 ± 0.032	1.632PheArg: 1.632 ± 0.035	2.781PheSer: 2.781 ± 0.051	1.957PheThr: 1.957 ± 0.04	2.483PheVal: 2.483 ± 0.048	0.567PheTrp: 0.567 ± 0.027	1.161PheTyr: 1.161 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.516GlyAla: 6.516 ± 0.085	1.136GlyCys: 1.136 ± 0.03	4.34GlyAsp: 4.34 ± 0.069	4.589GlyGlu: 4.589 ± 0.065	3.326GlyPhe: 3.326 ± 0.054	5.621GlyGly: 5.621 ± 0.09	1.976GlyHis: 1.976 ± 0.042	4.363GlyIle: 4.363 ± 0.066	3.403GlyLys: 3.403 ± 0.063	7.98GlyLeu: 7.98 ± 0.09	2.313GlyMet: 2.313 ± 0.043	2.572GlyAsn: 2.572 ± 0.048	2.181GlyPro: 2.181 ± 0.037	3.946GlyGln: 3.946 ± 0.061	4.246GlyArg: 4.246 ± 0.066	4.608GlySer: 4.608 ± 0.067	3.514GlyThr: 3.514 ± 0.057	5.663GlyVal: 5.663 ± 0.071	1.199GlyTrp: 1.199 ± 0.036	2.573GlyTyr: 2.573 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.751HisAla: 1.751 ± 0.042	0.444HisCys: 0.444 ± 0.021	1.141HisAsp: 1.141 ± 0.03	0.966HisGlu: 0.966 ± 0.026	1.068HisPhe: 1.068 ± 0.03	1.94HisGly: 1.94 ± 0.043	0.864HisHis: 0.864 ± 0.029	1.057HisIle: 1.057 ± 0.031	0.88HisLys: 0.88 ± 0.026	2.522HisLeu: 2.522 ± 0.052	0.485HisMet: 0.485 ± 0.02	0.928HisAsn: 0.928 ± 0.028	1.423HisPro: 1.423 ± 0.036	1.643HisGln: 1.643 ± 0.044	1.581HisArg: 1.581 ± 0.037	1.567HisSer: 1.567 ± 0.035	1.15HisThr: 1.15 ± 0.033	1.047HisVal: 1.047 ± 0.027	0.535HisTrp: 0.535 ± 0.021	0.972HisTyr: 0.972 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.489IleAla: 5.489 ± 0.071	0.557IleCys: 0.557 ± 0.022	3.758IleAsp: 3.758 ± 0.051	3.765IleGlu: 3.765 ± 0.059	1.437IlePhe: 1.437 ± 0.033	4.282IleGly: 4.282 ± 0.061	1.144IleHis: 1.144 ± 0.029	2.42IleIle: 2.42 ± 0.045	2.13IleLys: 2.13 ± 0.038	4.189IleLeu: 4.189 ± 0.064	1.044IleMet: 1.044 ± 0.032	2.252IleAsn: 2.252 ± 0.046	2.121IlePro: 2.121 ± 0.048	1.839IleGln: 1.839 ± 0.037	2.779IleArg: 2.779 ± 0.05	3.272IleSer: 3.272 ± 0.054	2.828IleThr: 2.828 ± 0.049	3.014IleVal: 3.014 ± 0.054	0.53IleTrp: 0.53 ± 0.017	1.234IleTyr: 1.234 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	4.169LysAla: 4.169 ± 0.071	0.268LysCys: 0.268 ± 0.015	1.865LysAsp: 1.865 ± 0.042	2.218LysGlu: 2.218 ± 0.052	1.111LysPhe: 1.111 ± 0.032	2.966LysGly: 2.966 ± 0.053	0.881LysHis: 0.881 ± 0.028	1.802LysIle: 1.802 ± 0.045	1.675LysLys: 1.675 ± 0.047	4.356LysLeu: 4.356 ± 0.065	1.056LysMet: 1.056 ± 0.029	1.076LysAsn: 1.076 ± 0.029	2.1LysPro: 2.1 ± 0.051	2.324LysGln: 2.324 ± 0.043	2.634LysArg: 2.634 ± 0.044	2.109LysSer: 2.109 ± 0.046	1.982LysThr: 1.982 ± 0.044	3.14LysVal: 3.14 ± 0.052	0.424LysTrp: 0.424 ± 0.018	0.921LysTyr: 0.921 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	12.65LeuAla: 12.65 ± 0.127	1.306LeuCys: 1.306 ± 0.038	6.142LeuAsp: 6.142 ± 0.077	6.095LeuGlu: 6.095 ± 0.09	4.161LeuPhe: 4.161 ± 0.074	8.037LeuGly: 8.037 ± 0.09	2.204LeuHis: 2.204 ± 0.047	5.19LeuIle: 5.19 ± 0.074	4.77LeuLys: 4.77 ± 0.068	12.25LeuLeu: 12.25 ± 0.151	3.267LeuMet: 3.267 ± 0.057	4.003LeuAsn: 4.003 ± 0.055	5.723LeuPro: 5.723 ± 0.071	4.784LeuGln: 4.784 ± 0.074	5.239LeuArg: 5.239 ± 0.071	8.149LeuSer: 8.149 ± 0.084	6.547LeuThr: 6.547 ± 0.075	7.908LeuVal: 7.908 ± 0.103	1.401LeuTrp: 1.401 ± 0.035	2.734LeuTyr: 2.734 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	3.34MetAla: 3.34 ± 0.061	0.183MetCys: 0.183 ± 0.011	1.359MetAsp: 1.359 ± 0.035	1.401MetGlu: 1.401 ± 0.031	0.775MetPhe: 0.775 ± 0.027	1.936MetGly: 1.936 ± 0.046	0.474MetHis: 0.474 ± 0.021	1.239MetIle: 1.239 ± 0.035	1.335MetLys: 1.335 ± 0.035	2.922MetLeu: 2.922 ± 0.054	0.914MetMet: 0.914 ± 0.029	0.987MetAsn: 0.987 ± 0.032	1.252MetPro: 1.252 ± 0.031	1.163MetGln: 1.163 ± 0.032	1.293MetArg: 1.293 ± 0.034	1.772MetSer: 1.772 ± 0.032	1.801MetThr: 1.801 ± 0.038	2.144MetVal: 2.144 ± 0.045	0.23MetTrp: 0.23 ± 0.013	0.42MetTyr: 0.42 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.108AsnAla: 3.108 ± 0.055	0.416AsnCys: 0.416 ± 0.019	2.013AsnAsp: 2.013 ± 0.058	1.756AsnGlu: 1.756 ± 0.039	1.135AsnPhe: 1.135 ± 0.031	2.832AsnGly: 2.832 ± 0.052	0.931AsnHis: 0.931 ± 0.031	1.623AsnIle: 1.623 ± 0.04	1.269AsnLys: 1.269 ± 0.034	3.74AsnLeu: 3.74 ± 0.064	0.767AsnMet: 0.767 ± 0.024	1.249AsnAsn: 1.249 ± 0.034	2.006AsnPro: 2.006 ± 0.04	1.906AsnGln: 1.906 ± 0.042	2.146AsnArg: 2.146 ± 0.045	1.912AsnSer: 1.912 ± 0.041	1.606AsnThr: 1.606 ± 0.039	2.002AsnVal: 2.002 ± 0.045	0.558AsnTrp: 0.558 ± 0.019	1.032AsnTyr: 1.032 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	4.152ProAla: 4.152 ± 0.063	0.403ProCys: 0.403 ± 0.021	2.752ProAsp: 2.752 ± 0.051	3.332ProGlu: 3.332 ± 0.058	1.686ProPhe: 1.686 ± 0.036	3.43ProGly: 3.43 ± 0.06	0.962ProHis: 0.962 ± 0.03	2.002ProIle: 2.002 ± 0.04	1.808ProLys: 1.808 ± 0.038	5.213ProLeu: 5.213 ± 0.078	1.311ProMet: 1.311 ± 0.03	1.376ProAsn: 1.376 ± 0.033	1.537ProPro: 1.537 ± 0.038	2.392ProGln: 2.392 ± 0.051	1.926ProArg: 1.926 ± 0.043	2.382ProSer: 2.382 ± 0.043	2.053ProThr: 2.053 ± 0.044	3.75ProVal: 3.75 ± 0.054	0.697ProTrp: 0.697 ± 0.023	1.202ProTyr: 1.202 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.648GlnAla: 5.648 ± 0.082	0.514GlnCys: 0.514 ± 0.024	2.079GlnAsp: 2.079 ± 0.042	2.351GlnGlu: 2.351 ± 0.046	1.866GlnPhe: 1.866 ± 0.043	4.058GlnGly: 4.058 ± 0.065	1.393GlnHis: 1.393 ± 0.032	2.214GlnIle: 2.214 ± 0.044	1.48GlnLys: 1.48 ± 0.036	6.817GlnLeu: 6.817 ± 0.115	1.389GlnMet: 1.389 ± 0.036	1.118GlnAsn: 1.118 ± 0.032	2.651GlnPro: 2.651 ± 0.05	4.617GlnGln: 4.617 ± 0.095	3.496GlnArg: 3.496 ± 0.061	2.869GlnSer: 2.869 ± 0.052	2.181GlnThr: 2.181 ± 0.043	3.767GlnVal: 3.767 ± 0.061	0.959GlnTrp: 0.959 ± 0.03	1.273GlnTyr: 1.273 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	4.484ArgAla: 4.484 ± 0.058	0.709ArgCys: 0.709 ± 0.024	2.843ArgAsp: 2.843 ± 0.046	2.935ArgGlu: 2.935 ± 0.054	2.613ArgPhe: 2.613 ± 0.044	3.341ArgGly: 3.341 ± 0.065	1.704ArgHis: 1.704 ± 0.044	3.106ArgIle: 3.106 ± 0.054	1.996ArgLys: 1.996 ± 0.045	6.901ArgLeu: 6.901 ± 0.092	1.45ArgMet: 1.45 ± 0.035	1.779ArgAsn: 1.779 ± 0.041	2.402ArgPro: 2.402 ± 0.043	3.777ArgGln: 3.777 ± 0.061	3.722ArgArg: 3.722 ± 0.073	3.046ArgSer: 3.046 ± 0.052	2.37ArgThr: 2.37 ± 0.041	3.956ArgVal: 3.956 ± 0.062	0.934ArgTrp: 0.934 ± 0.029	2.102ArgTyr: 2.102 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	5.631SerAla: 5.631 ± 0.064	0.731SerCys: 0.731 ± 0.033	3.707SerAsp: 3.707 ± 0.06	3.389SerGlu: 3.389 ± 0.049	2.301SerPhe: 2.301 ± 0.041	5.468SerGly: 5.468 ± 0.074	1.539SerHis: 1.539 ± 0.031	2.921SerIle: 2.921 ± 0.047	2.27SerLys: 2.27 ± 0.044	7.206SerLeu: 7.206 ± 0.089	1.603SerMet: 1.603 ± 0.037	2.104SerAsn: 2.104 ± 0.047	2.548SerPro: 2.548 ± 0.049	3.133SerGln: 3.133 ± 0.058	3.551SerArg: 3.551 ± 0.053	3.559SerSer: 3.559 ± 0.06	2.763SerThr: 2.763 ± 0.044	4.336SerVal: 4.336 ± 0.063	0.932SerTrp: 0.932 ± 0.029	1.83SerTyr: 1.83 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.732ThrAla: 4.732 ± 0.068	0.51ThrCys: 0.51 ± 0.023	2.845ThrAsp: 2.845 ± 0.054	3.033ThrGlu: 3.033 ± 0.056	1.654ThrPhe: 1.654 ± 0.036	4.112ThrGly: 4.112 ± 0.06	1.091ThrHis: 1.091 ± 0.031	2.534ThrIle: 2.534 ± 0.049	1.556ThrLys: 1.556 ± 0.037	7.241ThrLeu: 7.241 ± 0.08	1.116ThrMet: 1.116 ± 0.028	1.48ThrAsn: 1.48 ± 0.034	2.865ThrPro: 2.865 ± 0.048	2.277ThrGln: 2.277 ± 0.045	2.61ThrArg: 2.61 ± 0.044	2.778ThrSer: 2.778 ± 0.049	2.627ThrThr: 2.627 ± 0.048	3.69ThrVal: 3.69 ± 0.057	0.515ThrTrp: 0.515 ± 0.022	1.165ThrTyr: 1.165 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	7.689ValAla: 7.689 ± 0.095	0.802ValCys: 0.802 ± 0.026	4.44ValAsp: 4.44 ± 0.06	4.316ValGlu: 4.316 ± 0.064	2.414ValPhe: 2.414 ± 0.044	4.811ValGly: 4.811 ± 0.067	1.37ValHis: 1.37 ± 0.033	4.022ValIle: 4.022 ± 0.063	2.751ValLys: 2.751 ± 0.055	7.139ValLeu: 7.139 ± 0.083	2.057ValMet: 2.057 ± 0.043	2.545ValAsn: 2.545 ± 0.048	2.869ValPro: 2.869 ± 0.049	2.484ValGln: 2.484 ± 0.045	3.443ValArg: 3.443 ± 0.055	4.675ValSer: 4.675 ± 0.069	4.187ValThr: 4.187 ± 0.061	5.811ValVal: 5.811 ± 0.087	0.786ValTrp: 0.786 ± 0.028	1.675ValTyr: 1.675 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.004TrpAla: 1.004 ± 0.034	0.191TrpCys: 0.191 ± 0.013	0.647TrpAsp: 0.647 ± 0.022	0.507TrpGlu: 0.507 ± 0.019	0.564TrpPhe: 0.564 ± 0.024	0.892TrpGly: 0.892 ± 0.029	0.409TrpHis: 0.409 ± 0.018	0.582TrpIle: 0.582 ± 0.022	0.411TrpLys: 0.411 ± 0.018	2.057TrpLeu: 2.057 ± 0.045	0.367TrpMet: 0.367 ± 0.017	0.437TrpAsn: 0.437 ± 0.022	0.654TrpPro: 0.654 ± 0.024	1.344TrpGln: 1.344 ± 0.042	0.942TrpArg: 0.942 ± 0.031	0.824TrpSer: 0.824 ± 0.026	0.481TrpThr: 0.481 ± 0.02	0.932TrpVal: 0.932 ± 0.029	0.251TrpTrp: 0.251 ± 0.015	0.378TrpTyr: 0.378 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.178TyrAla: 2.178 ± 0.042	0.376TyrCys: 0.376 ± 0.017	1.596TyrAsp: 1.596 ± 0.04	1.192TyrGlu: 1.192 ± 0.032	1.062TyrPhe: 1.062 ± 0.03	2.259TyrGly: 2.259 ± 0.048	0.804TyrHis: 0.804 ± 0.024	1.145TyrIle: 1.145 ± 0.032	0.839TyrLys: 0.839 ± 0.025	3.582TyrLeu: 3.582 ± 0.061	0.547TyrMet: 0.547 ± 0.019	0.922TyrAsn: 0.922 ± 0.029	1.386TyrPro: 1.386 ± 0.035	1.914TyrGln: 1.914 ± 0.037	2.118TyrArg: 2.118 ± 0.044	1.678TyrSer: 1.678 ± 0.043	1.254TyrThr: 1.254 ± 0.037	1.536TyrVal: 1.536 ± 0.031	0.444TyrTrp: 0.444 ± 0.02	0.883TyrTyr: 0.883 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3939 proteins (1277342 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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