Amino acid dipepetide frequency for Weissella paramesenteroides ATCC 33313

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.682AlaAla: 7.682 ± 0.181
0.184AlaCys: 0.184 ± 0.021
5.357AlaAsp: 5.357 ± 0.11
4.784AlaGlu: 4.784 ± 0.112
3.186AlaPhe: 3.186 ± 0.079
6.075AlaGly: 6.075 ± 0.122
1.69AlaHis: 1.69 ± 0.057
6.523AlaIle: 6.523 ± 0.114
5.16AlaLys: 5.16 ± 0.109
7.77AlaLeu: 7.77 ± 0.138
2.417AlaMet: 2.417 ± 0.07
3.961AlaAsn: 3.961 ± 0.095
2.327AlaPro: 2.327 ± 0.066
3.474AlaGln: 3.474 ± 0.093
2.967AlaArg: 2.967 ± 0.083
4.582AlaSer: 4.582 ± 0.12
5.379AlaThr: 5.379 ± 0.101
5.971AlaVal: 5.971 ± 0.121
0.903AlaTrp: 0.903 ± 0.036
2.722AlaTyr: 2.722 ± 0.084
0.0AlaXaa: 0.0 ± 0.0
Cys
0.165CysAla: 0.165 ± 0.019
0.033CysCys: 0.033 ± 0.008
0.092CysAsp: 0.092 ± 0.014
0.129CysGlu: 0.129 ± 0.015
0.085CysPhe: 0.085 ± 0.012
0.212CysGly: 0.212 ± 0.02
0.092CysHis: 0.092 ± 0.013
0.197CysIle: 0.197 ± 0.021
0.08CysLys: 0.08 ± 0.011
0.306CysLeu: 0.306 ± 0.024
0.049CysMet: 0.049 ± 0.009
0.063CysAsn: 0.063 ± 0.011
0.099CysPro: 0.099 ± 0.013
0.141CysGln: 0.141 ± 0.019
0.089CysArg: 0.089 ± 0.013
0.134CysSer: 0.134 ± 0.015
0.144CysThr: 0.144 ± 0.018
0.148CysVal: 0.148 ± 0.016
0.045CysTrp: 0.045 ± 0.01
0.097CysTyr: 0.097 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
4.392AspAla: 4.392 ± 0.098
0.106AspCys: 0.106 ± 0.015
3.712AspAsp: 3.712 ± 0.098
4.584AspGlu: 4.584 ± 0.103
2.696AspPhe: 2.696 ± 0.074
3.743AspGly: 3.743 ± 0.085
1.241AspHis: 1.241 ± 0.047
4.187AspIle: 4.187 ± 0.097
3.613AspLys: 3.613 ± 0.086
5.491AspLeu: 5.491 ± 0.103
1.683AspMet: 1.683 ± 0.051
2.725AspAsn: 2.725 ± 0.069
1.939AspPro: 1.939 ± 0.062
2.49AspGln: 2.49 ± 0.065
2.219AspArg: 2.219 ± 0.059
2.894AspSer: 2.894 ± 0.075
3.059AspThr: 3.059 ± 0.078
4.471AspVal: 4.471 ± 0.095
0.83AspTrp: 0.83 ± 0.04
2.456AspTyr: 2.456 ± 0.072
0.0AspXaa: 0.0 ± 0.0
Glu
4.389GluAla: 4.389 ± 0.091
0.097GluCys: 0.097 ± 0.014
2.817GluAsp: 2.817 ± 0.077
3.394GluGlu: 3.394 ± 0.097
2.245GluPhe: 2.245 ± 0.063
2.73GluGly: 2.73 ± 0.084
1.222GluHis: 1.222 ± 0.046
4.06GluIle: 4.06 ± 0.095
4.032GluLys: 4.032 ± 0.097
5.995GluLeu: 5.995 ± 0.13
1.78GluMet: 1.78 ± 0.058
3.131GluAsn: 3.131 ± 0.069
1.745GluPro: 1.745 ± 0.059
2.99GluGln: 2.99 ± 0.1
2.596GluArg: 2.596 ± 0.065
2.863GluSer: 2.863 ± 0.066
3.54GluThr: 3.54 ± 0.083
3.87GluVal: 3.87 ± 0.084
0.546GluTrp: 0.546 ± 0.03
1.721GluTyr: 1.721 ± 0.061
0.0GluXaa: 0.0 ± 0.0
Phe
3.437PheAla: 3.437 ± 0.085
0.122PheCys: 0.122 ± 0.014
2.805PheAsp: 2.805 ± 0.063
2.254PheGlu: 2.254 ± 0.061
1.956PhePhe: 1.956 ± 0.07
3.679PheGly: 3.679 ± 0.103
0.755PheHis: 0.755 ± 0.036
3.428PheIle: 3.428 ± 0.102
2.466PheLys: 2.466 ± 0.069
3.721PheLeu: 3.721 ± 0.101
1.255PheMet: 1.255 ± 0.054
2.188PheAsn: 2.188 ± 0.062
1.399PhePro: 1.399 ± 0.049
1.33PheGln: 1.33 ± 0.044
1.281PheArg: 1.281 ± 0.051
2.871PheSer: 2.871 ± 0.086
2.489PheThr: 2.489 ± 0.071
3.106PheVal: 3.106 ± 0.074
0.55PheTrp: 0.55 ± 0.036
1.528PheTyr: 1.528 ± 0.061
0.0PheXaa: 0.0 ± 0.0
Gly
5.05GlyAla: 5.05 ± 0.122
0.171GlyCys: 0.171 ± 0.021
3.554GlyAsp: 3.554 ± 0.084
3.508GlyGlu: 3.508 ± 0.086
3.11GlyPhe: 3.11 ± 0.092
4.453GlyGly: 4.453 ± 0.111
1.589GlyHis: 1.589 ± 0.054
5.487GlyIle: 5.487 ± 0.121
4.22GlyLys: 4.22 ± 0.11
6.791GlyLeu: 6.791 ± 0.132
2.029GlyMet: 2.029 ± 0.062
2.844GlyAsn: 2.844 ± 0.074
1.523GlyPro: 1.523 ± 0.051
3.004GlyGln: 3.004 ± 0.084
2.722GlyArg: 2.722 ± 0.074
3.917GlySer: 3.917 ± 0.076
4.164GlyThr: 4.164 ± 0.095
5.351GlyVal: 5.351 ± 0.106
0.874GlyTrp: 0.874 ± 0.046
2.696GlyTyr: 2.696 ± 0.064
0.0GlyXaa: 0.0 ± 0.0
His
1.61HisAla: 1.61 ± 0.051
0.075HisCys: 0.075 ± 0.014
1.338HisAsp: 1.338 ± 0.053
1.338HisGlu: 1.338 ± 0.05
1.015HisPhe: 1.015 ± 0.04
1.472HisGly: 1.472 ± 0.055
0.64HisHis: 0.64 ± 0.035
1.425HisIle: 1.425 ± 0.043
1.051HisLys: 1.051 ± 0.04
2.076HisLeu: 2.076 ± 0.07
0.55HisMet: 0.55 ± 0.032
0.884HisAsn: 0.884 ± 0.038
0.901HisPro: 0.901 ± 0.034
1.138HisGln: 1.138 ± 0.053
0.945HisArg: 0.945 ± 0.04
1.084HisSer: 1.084 ± 0.041
1.107HisThr: 1.107 ± 0.049
1.542HisVal: 1.542 ± 0.058
0.292HisTrp: 0.292 ± 0.023
0.881HisTyr: 0.881 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
6.773IleAla: 6.773 ± 0.141
0.263IleCys: 0.263 ± 0.025
4.612IleAsp: 4.612 ± 0.09
3.543IleGlu: 3.543 ± 0.079
3.303IlePhe: 3.303 ± 0.085
5.51IleGly: 5.51 ± 0.122
1.347IleHis: 1.347 ± 0.051
5.672IleIle: 5.672 ± 0.15
4.345IleLys: 4.345 ± 0.117
6.782IleLeu: 6.782 ± 0.147
1.975IleMet: 1.975 ± 0.061
3.799IleAsn: 3.799 ± 0.093
2.509IlePro: 2.509 ± 0.067
2.737IleGln: 2.737 ± 0.069
2.576IleArg: 2.576 ± 0.072
4.683IleSer: 4.683 ± 0.107
4.349IleThr: 4.349 ± 0.094
5.463IleVal: 5.463 ± 0.113
0.821IleTrp: 0.821 ± 0.043
2.248IleTyr: 2.248 ± 0.069
0.0IleXaa: 0.0 ± 0.0
Lys
4.405LysAla: 4.405 ± 0.108
0.064LysCys: 0.064 ± 0.01
3.068LysAsp: 3.068 ± 0.079
3.552LysGlu: 3.552 ± 0.093
2.113LysPhe: 2.113 ± 0.062
3.077LysGly: 3.077 ± 0.078
1.213LysHis: 1.213 ± 0.045
4.375LysIle: 4.375 ± 0.1
4.542LysLys: 4.542 ± 0.117
5.63LysLeu: 5.63 ± 0.107
2.137LysMet: 2.137 ± 0.072
3.324LysAsn: 3.324 ± 0.092
2.003LysPro: 2.003 ± 0.056
3.461LysGln: 3.461 ± 0.095
2.804LysArg: 2.804 ± 0.072
3.634LysSer: 3.634 ± 0.1
3.712LysThr: 3.712 ± 0.091
3.983LysVal: 3.983 ± 0.09
0.651LysTrp: 0.651 ± 0.037
2.233LysTyr: 2.233 ± 0.067
0.0LysXaa: 0.0 ± 0.0
Leu
9.037LeuAla: 9.037 ± 0.135
0.256LeuCys: 0.256 ± 0.021
5.353LeuAsp: 5.353 ± 0.101
4.384LeuGlu: 4.384 ± 0.097
3.999LeuPhe: 3.999 ± 0.12
6.425LeuGly: 6.425 ± 0.126
1.928LeuHis: 1.928 ± 0.064
7.165LeuIle: 7.165 ± 0.174
5.506LeuLys: 5.506 ± 0.095
9.119LeuLeu: 9.119 ± 0.19
2.664LeuMet: 2.664 ± 0.083
4.652LeuAsn: 4.652 ± 0.092
4.291LeuPro: 4.291 ± 0.105
4.093LeuGln: 4.093 ± 0.095
3.759LeuArg: 3.759 ± 0.093
6.77LeuSer: 6.77 ± 0.124
6.862LeuThr: 6.862 ± 0.131
7.065LeuVal: 7.065 ± 0.118
0.973LeuTrp: 0.973 ± 0.047
2.704LeuTyr: 2.704 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
2.729MetAla: 2.729 ± 0.075
0.068MetCys: 0.068 ± 0.009
1.356MetAsp: 1.356 ± 0.051
0.975MetGlu: 0.975 ± 0.04
1.088MetPhe: 1.088 ± 0.05
1.874MetGly: 1.874 ± 0.066
0.536MetHis: 0.536 ± 0.034
2.121MetIle: 2.121 ± 0.059
1.665MetLys: 1.665 ± 0.055
2.621MetLeu: 2.621 ± 0.08
0.891MetMet: 0.891 ± 0.046
1.465MetAsn: 1.465 ± 0.052
1.211MetPro: 1.211 ± 0.052
1.342MetGln: 1.342 ± 0.044
1.147MetArg: 1.147 ± 0.043
1.826MetSer: 1.826 ± 0.058
2.315MetThr: 2.315 ± 0.06
2.081MetVal: 2.081 ± 0.057
0.221MetTrp: 0.221 ± 0.02
0.734MetTyr: 0.734 ± 0.034
0.0MetXaa: 0.0 ± 0.0
Asn
3.512AsnAla: 3.512 ± 0.095
0.111AsnCys: 0.111 ± 0.016
3.026AsnAsp: 3.026 ± 0.077
2.866AsnGlu: 2.866 ± 0.072
1.979AsnPhe: 1.979 ± 0.067
3.46AsnGly: 3.46 ± 0.083
1.22AsnHis: 1.22 ± 0.049
3.275AsnIle: 3.275 ± 0.09
2.965AsnLys: 2.965 ± 0.088
4.236AsnLeu: 4.236 ± 0.091
1.363AsnMet: 1.363 ± 0.053
2.56AsnAsn: 2.56 ± 0.091
2.036AsnPro: 2.036 ± 0.062
2.563AsnGln: 2.563 ± 0.069
1.954AsnArg: 1.954 ± 0.061
2.457AsnSer: 2.457 ± 0.085
2.57AsnThr: 2.57 ± 0.074
3.272AsnVal: 3.272 ± 0.08
0.717AsnTrp: 0.717 ± 0.036
1.866AsnTyr: 1.866 ± 0.06
0.0AsnXaa: 0.0 ± 0.0
Pro
2.847ProAla: 2.847 ± 0.074
0.084ProCys: 0.084 ± 0.012
2.349ProAsp: 2.349 ± 0.074
2.739ProGlu: 2.739 ± 0.068
1.564ProPhe: 1.564 ± 0.05
2.154ProGly: 2.154 ± 0.065
0.62ProHis: 0.62 ± 0.031
2.49ProIle: 2.49 ± 0.062
2.163ProLys: 2.163 ± 0.069
3.157ProLeu: 3.157 ± 0.078
0.908ProMet: 0.908 ± 0.039
1.773ProAsn: 1.773 ± 0.055
0.435ProPro: 0.435 ± 0.029
1.323ProGln: 1.323 ± 0.052
1.058ProArg: 1.058 ± 0.042
1.86ProSer: 1.86 ± 0.059
2.391ProThr: 2.391 ± 0.064
2.882ProVal: 2.882 ± 0.068
0.357ProTrp: 0.357 ± 0.028
1.281ProTyr: 1.281 ± 0.047
0.0ProXaa: 0.0 ± 0.0
Gln
4.01GlnAla: 4.01 ± 0.091
0.08GlnCys: 0.08 ± 0.014
2.057GlnAsp: 2.057 ± 0.059
2.266GlnGlu: 2.266 ± 0.064
1.697GlnPhe: 1.697 ± 0.055
2.421GlnGly: 2.421 ± 0.066
1.093GlnHis: 1.093 ± 0.042
3.164GlnIle: 3.164 ± 0.077
2.851GlnLys: 2.851 ± 0.076
5.007GlnLeu: 5.007 ± 0.12
1.248GlnMet: 1.248 ± 0.051
2.099GlnAsn: 2.099 ± 0.057
1.726GlnPro: 1.726 ± 0.061
3.005GlnGln: 3.005 ± 0.108
2.097GlnArg: 2.097 ± 0.067
2.69GlnSer: 2.69 ± 0.078
3.131GlnThr: 3.131 ± 0.079
3.336GlnVal: 3.336 ± 0.081
0.486GlnTrp: 0.486 ± 0.032
1.683GlnTyr: 1.683 ± 0.055
0.0GlnXaa: 0.0 ± 0.0
Arg
2.783ArgAla: 2.783 ± 0.077
0.092ArgCys: 0.092 ± 0.015
2.245ArgAsp: 2.245 ± 0.058
2.593ArgGlu: 2.593 ± 0.077
1.832ArgPhe: 1.832 ± 0.06
2.375ArgGly: 2.375 ± 0.064
1.114ArgHis: 1.114 ± 0.043
2.748ArgIle: 2.748 ± 0.07
2.297ArgLys: 2.297 ± 0.069
4.027ArgLeu: 4.027 ± 0.099
1.098ArgMet: 1.098 ± 0.041
1.645ArgAsn: 1.645 ± 0.054
1.401ArgPro: 1.401 ± 0.048
2.276ArgGln: 2.276 ± 0.062
2.029ArgArg: 2.029 ± 0.072
2.088ArgSer: 2.088 ± 0.064
2.074ArgThr: 2.074 ± 0.057
2.854ArgVal: 2.854 ± 0.078
0.411ArgTrp: 0.411 ± 0.027
1.554ArgTyr: 1.554 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
4.857SerAla: 4.857 ± 0.111
0.111SerCys: 0.111 ± 0.016
3.668SerAsp: 3.668 ± 0.094
3.637SerGlu: 3.637 ± 0.084
2.812SerPhe: 2.812 ± 0.075
4.439SerGly: 4.439 ± 0.095
1.246SerHis: 1.246 ± 0.045
3.801SerIle: 3.801 ± 0.089
3.209SerLys: 3.209 ± 0.071
6.074SerLeu: 6.074 ± 0.118
1.514SerMet: 1.514 ± 0.057
2.614SerAsn: 2.614 ± 0.083
1.702SerPro: 1.702 ± 0.053
2.694SerGln: 2.694 ± 0.079
2.342SerArg: 2.342 ± 0.065
3.91SerSer: 3.91 ± 0.206
3.42SerThr: 3.42 ± 0.09
4.506SerVal: 4.506 ± 0.097
0.75SerTrp: 0.75 ± 0.039
2.12SerTyr: 2.12 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
5.219ThrAla: 5.219 ± 0.112
0.125ThrCys: 0.125 ± 0.015
3.863ThrAsp: 3.863 ± 0.091
3.235ThrGlu: 3.235 ± 0.089
2.661ThrPhe: 2.661 ± 0.072
4.662ThrGly: 4.662 ± 0.095
1.209ThrHis: 1.209 ± 0.048
4.796ThrIle: 4.796 ± 0.1
3.597ThrLys: 3.597 ± 0.083
6.197ThrLeu: 6.197 ± 0.123
1.571ThrMet: 1.571 ± 0.059
2.955ThrAsn: 2.955 ± 0.078
2.607ThrPro: 2.607 ± 0.067
2.332ThrGln: 2.332 ± 0.067
2.047ThrArg: 2.047 ± 0.064
3.702ThrSer: 3.702 ± 0.096
4.276ThrThr: 4.276 ± 0.112
4.915ThrVal: 4.915 ± 0.101
0.733ThrTrp: 0.733 ± 0.041
2.139ThrTyr: 2.139 ± 0.068
0.0ThrXaa: 0.0 ± 0.0
Val
6.824ValAla: 6.824 ± 0.112
0.212ValCys: 0.212 ± 0.023
4.513ValAsp: 4.513 ± 0.093
3.541ValGlu: 3.541 ± 0.095
2.918ValPhe: 2.918 ± 0.075
5.129ValGly: 5.129 ± 0.115
1.33ValHis: 1.33 ± 0.045
5.536ValIle: 5.536 ± 0.104
4.185ValLys: 4.185 ± 0.102
6.898ValLeu: 6.898 ± 0.128
1.923ValMet: 1.923 ± 0.059
3.425ValAsn: 3.425 ± 0.082
2.988ValPro: 2.988 ± 0.067
2.696ValGln: 2.696 ± 0.071
2.682ValArg: 2.682 ± 0.074
4.906ValSer: 4.906 ± 0.103
5.172ValThr: 5.172 ± 0.101
5.98ValVal: 5.98 ± 0.111
0.762ValTrp: 0.762 ± 0.043
2.273ValTyr: 2.273 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
0.743TrpAla: 0.743 ± 0.039
0.038TrpCys: 0.038 ± 0.009
0.536TrpAsp: 0.536 ± 0.032
0.506TrpGlu: 0.506 ± 0.032
0.621TrpPhe: 0.621 ± 0.039
0.719TrpGly: 0.719 ± 0.037
0.426TrpHis: 0.426 ± 0.031
0.736TrpIle: 0.736 ± 0.041
0.339TrpLys: 0.339 ± 0.029
1.589TrpLeu: 1.589 ± 0.056
0.31TrpMet: 0.31 ± 0.022
0.399TrpAsn: 0.399 ± 0.038
0.334TrpPro: 0.334 ± 0.027
0.919TrpGln: 0.919 ± 0.046
0.602TrpArg: 0.602 ± 0.033
0.719TrpSer: 0.719 ± 0.038
0.595TrpThr: 0.595 ± 0.034
0.78TrpVal: 0.78 ± 0.039
0.202TrpTrp: 0.202 ± 0.021
0.435TrpTyr: 0.435 ± 0.029
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.65TyrAla: 2.65 ± 0.077
0.108TyrCys: 0.108 ± 0.015
2.208TyrAsp: 2.208 ± 0.071
1.937TyrGlu: 1.937 ± 0.058
1.739TyrPhe: 1.739 ± 0.068
2.445TyrGly: 2.445 ± 0.07
0.854TyrHis: 0.854 ± 0.044
2.125TyrIle: 2.125 ± 0.075
1.693TyrLys: 1.693 ± 0.06
3.521TyrLeu: 3.521 ± 0.085
0.898TyrMet: 0.898 ± 0.041
1.505TyrAsn: 1.505 ± 0.055
1.258TyrPro: 1.258 ± 0.046
2.137TyrGln: 2.137 ± 0.069
1.622TyrArg: 1.622 ± 0.054
1.836TyrSer: 1.836 ± 0.063
2.092TyrThr: 2.092 ± 0.063
2.316TyrVal: 2.316 ± 0.065
0.425TyrTrp: 0.425 ± 0.029
1.385TyrTyr: 1.385 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1952 proteins (574627 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski