Amino acid dipepetide frequency for Cinnamomum micranthum f. kanehirae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.271AlaAla: 6.271 ± 0.04
1.29AlaCys: 1.29 ± 0.014
3.05AlaAsp: 3.05 ± 0.018
4.099AlaGlu: 4.099 ± 0.025
2.872AlaPhe: 2.872 ± 0.018
4.254AlaGly: 4.254 ± 0.035
1.387AlaHis: 1.387 ± 0.013
3.893AlaIle: 3.893 ± 0.02
3.57AlaLys: 3.57 ± 0.021
6.697AlaLeu: 6.697 ± 0.028
1.866AlaMet: 1.866 ± 0.014
2.493AlaAsn: 2.493 ± 0.017
2.88AlaPro: 2.88 ± 0.021
2.1AlaGln: 2.1 ± 0.015
3.49AlaArg: 3.49 ± 0.029
5.925AlaSer: 5.925 ± 0.024
3.545AlaThr: 3.545 ± 0.021
4.706AlaVal: 4.706 ± 0.022
0.813AlaTrp: 0.813 ± 0.009
1.818AlaTyr: 1.818 ± 0.015
0.0AlaXaa: 0.0 ± 0.0
Cys
0.986CysAla: 0.986 ± 0.01
0.537CysCys: 0.537 ± 0.007
0.87CysAsp: 0.87 ± 0.01
0.886CysGlu: 0.886 ± 0.009
0.903CysPhe: 0.903 ± 0.011
1.416CysGly: 1.416 ± 0.013
0.477CysHis: 0.477 ± 0.006
1.09CysIle: 1.09 ± 0.01
1.139CysLys: 1.139 ± 0.012
1.93CysLeu: 1.93 ± 0.013
0.504CysMet: 0.504 ± 0.006
0.921CysAsn: 0.921 ± 0.011
1.007CysPro: 1.007 ± 0.011
0.617CysGln: 0.617 ± 0.007
1.126CysArg: 1.126 ± 0.011
1.922CysSer: 1.922 ± 0.016
0.874CysThr: 0.874 ± 0.009
1.021CysVal: 1.021 ± 0.009
0.259CysTrp: 0.259 ± 0.005
0.551CysTyr: 0.551 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
3.492AspAla: 3.492 ± 0.016
1.014AspCys: 1.014 ± 0.01
3.432AspAsp: 3.432 ± 0.027
3.842AspGlu: 3.842 ± 0.023
2.345AspPhe: 2.345 ± 0.015
3.978AspGly: 3.978 ± 0.021
1.188AspHis: 1.188 ± 0.012
2.93AspIle: 2.93 ± 0.017
2.407AspLys: 2.407 ± 0.015
5.249AspLeu: 5.249 ± 0.028
1.342AspMet: 1.342 ± 0.012
1.893AspAsn: 1.893 ± 0.014
2.707AspPro: 2.707 ± 0.019
1.653AspGln: 1.653 ± 0.014
2.539AspArg: 2.539 ± 0.019
4.072AspSer: 4.072 ± 0.023
2.117AspThr: 2.117 ± 0.013
3.605AspVal: 3.605 ± 0.019
0.728AspTrp: 0.728 ± 0.009
1.478AspTyr: 1.478 ± 0.014
0.0AspXaa: 0.0 ± 0.0
Glu
4.653GluAla: 4.653 ± 0.024
0.934GluCys: 0.934 ± 0.01
3.837GluAsp: 3.837 ± 0.026
6.468GluGlu: 6.468 ± 0.051
2.296GluPhe: 2.296 ± 0.017
3.932GluGly: 3.932 ± 0.031
1.239GluHis: 1.239 ± 0.01
3.817GluIle: 3.817 ± 0.019
4.617GluLys: 4.617 ± 0.028
5.936GluLeu: 5.936 ± 0.034
1.976GluMet: 1.976 ± 0.015
2.971GluAsn: 2.971 ± 0.021
2.057GluPro: 2.057 ± 0.019
2.038GluGln: 2.038 ± 0.017
3.764GluArg: 3.764 ± 0.03
4.502GluSer: 4.502 ± 0.024
2.898GluThr: 2.898 ± 0.017
4.037GluVal: 4.037 ± 0.022
0.789GluTrp: 0.789 ± 0.008
1.551GluTyr: 1.551 ± 0.012
0.0GluXaa: 0.0 ± 0.0
Phe
2.482PheAla: 2.482 ± 0.015
0.906PheCys: 0.906 ± 0.011
2.286PheAsp: 2.286 ± 0.017
2.226PheGlu: 2.226 ± 0.014
2.13PhePhe: 2.13 ± 0.02
3.087PheGly: 3.087 ± 0.021
1.161PheHis: 1.161 ± 0.01
2.18PheIle: 2.18 ± 0.016
2.005PheLys: 2.005 ± 0.015
4.5PheLeu: 4.5 ± 0.028
0.984PheMet: 0.984 ± 0.011
1.778PheAsn: 1.778 ± 0.014
2.164PhePro: 2.164 ± 0.015
1.599PheGln: 1.599 ± 0.012
2.049PheArg: 2.049 ± 0.014
4.239PheSer: 4.239 ± 0.023
1.951PheThr: 1.951 ± 0.015
2.626PheVal: 2.626 ± 0.016
0.568PheTrp: 0.568 ± 0.008
1.283PheTyr: 1.283 ± 0.011
0.0PheXaa: 0.0 ± 0.0
Gly
3.913GlyAla: 3.913 ± 0.034
1.401GlyCys: 1.401 ± 0.013
3.399GlyAsp: 3.399 ± 0.017
3.882GlyGlu: 3.882 ± 0.03
3.252GlyPhe: 3.252 ± 0.02
5.465GlyGly: 5.465 ± 0.048
1.634GlyHis: 1.634 ± 0.014
3.755GlyIle: 3.755 ± 0.022
4.01GlyLys: 4.01 ± 0.024
6.151GlyLeu: 6.151 ± 0.031
1.623GlyMet: 1.623 ± 0.014
3.13GlyAsn: 3.13 ± 0.023
2.651GlyPro: 2.651 ± 0.02
2.136GlyGln: 2.136 ± 0.016
4.079GlyArg: 4.079 ± 0.045
6.037GlySer: 6.037 ± 0.024
3.328GlyThr: 3.328 ± 0.022
4.275GlyVal: 4.275 ± 0.023
0.972GlyTrp: 0.972 ± 0.011
2.056GlyTyr: 2.056 ± 0.017
0.0GlyXaa: 0.0 ± 0.0
His
1.446HisAla: 1.446 ± 0.013
0.56HisCys: 0.56 ± 0.006
1.143HisAsp: 1.143 ± 0.01
1.266HisGlu: 1.266 ± 0.01
1.125HisPhe: 1.125 ± 0.012
1.807HisGly: 1.807 ± 0.014
0.956HisHis: 0.956 ± 0.013
1.245HisIle: 1.245 ± 0.011
1.07HisLys: 1.07 ± 0.01
2.72HisLeu: 2.72 ± 0.017
0.584HisMet: 0.584 ± 0.007
0.949HisAsn: 0.949 ± 0.009
1.486HisPro: 1.486 ± 0.013
1.031HisGln: 1.031 ± 0.011
1.442HisArg: 1.442 ± 0.012
1.972HisSer: 1.972 ± 0.014
1.029HisThr: 1.029 ± 0.011
1.564HisVal: 1.564 ± 0.014
0.316HisTrp: 0.316 ± 0.006
0.674HisTyr: 0.674 ± 0.008
0.0HisXaa: 0.0 ± 0.0
Ile
3.662IleAla: 3.662 ± 0.022
1.133IleCys: 1.133 ± 0.01
2.943IleAsp: 2.943 ± 0.02
3.22IleGlu: 3.22 ± 0.019
2.312IlePhe: 2.312 ± 0.018
3.569IleGly: 3.569 ± 0.02
1.391IleHis: 1.391 ± 0.014
2.842IleIle: 2.842 ± 0.019
2.845IleLys: 2.845 ± 0.018
5.284IleLeu: 5.284 ± 0.024
1.126IleMet: 1.126 ± 0.009
2.125IleAsn: 2.125 ± 0.015
3.289IlePro: 3.289 ± 0.024
2.023IleGln: 2.023 ± 0.014
2.727IleArg: 2.727 ± 0.018
5.199IleSer: 5.199 ± 0.025
2.608IleThr: 2.608 ± 0.013
3.339IleVal: 3.339 ± 0.019
0.753IleTrp: 0.753 ± 0.009
1.554IleTyr: 1.554 ± 0.012
0.0IleXaa: 0.0 ± 0.0
Lys
3.885LysAla: 3.885 ± 0.019
0.969LysCys: 0.969 ± 0.012
3.084LysAsp: 3.084 ± 0.02
4.664LysGlu: 4.664 ± 0.03
1.936LysPhe: 1.936 ± 0.015
3.646LysGly: 3.646 ± 0.023
1.252LysHis: 1.252 ± 0.013
3.085LysIle: 3.085 ± 0.02
4.489LysLys: 4.489 ± 0.03
5.546LysLeu: 5.546 ± 0.024
1.562LysMet: 1.562 ± 0.012
2.487LysAsn: 2.487 ± 0.016
2.616LysPro: 2.616 ± 0.02
2.139LysGln: 2.139 ± 0.018
3.628LysArg: 3.628 ± 0.024
4.279LysSer: 4.279 ± 0.023
2.712LysThr: 2.712 ± 0.015
3.58LysVal: 3.58 ± 0.018
0.778LysTrp: 0.778 ± 0.008
1.453LysTyr: 1.453 ± 0.012
0.0LysXaa: 0.0 ± 0.0
Leu
6.437LeuAla: 6.437 ± 0.029
1.889LeuCys: 1.889 ± 0.014
5.158LeuAsp: 5.158 ± 0.025
6.391LeuGlu: 6.391 ± 0.04
3.988LeuPhe: 3.988 ± 0.024
6.021LeuGly: 6.021 ± 0.031
2.807LeuHis: 2.807 ± 0.017
4.745LeuIle: 4.745 ± 0.027
6.068LeuLys: 6.068 ± 0.029
10.524LeuLeu: 10.524 ± 0.043
2.207LeuMet: 2.207 ± 0.014
3.893LeuAsn: 3.893 ± 0.022
5.511LeuPro: 5.511 ± 0.027
4.505LeuGln: 4.505 ± 0.023
5.643LeuArg: 5.643 ± 0.027
9.219LeuSer: 9.219 ± 0.044
4.612LeuThr: 4.612 ± 0.026
6.227LeuVal: 6.227 ± 0.027
1.18LeuTrp: 1.18 ± 0.011
2.527LeuTyr: 2.527 ± 0.017
0.0LeuXaa: 0.0 ± 0.0
Met
2.17MetAla: 2.17 ± 0.016
0.326MetCys: 0.326 ± 0.005
1.52MetAsp: 1.52 ± 0.011
2.141MetGlu: 2.141 ± 0.016
0.813MetPhe: 0.813 ± 0.009
1.874MetGly: 1.874 ± 0.013
0.586MetHis: 0.586 ± 0.008
1.233MetIle: 1.233 ± 0.012
1.735MetLys: 1.735 ± 0.014
2.211MetLeu: 2.211 ± 0.016
0.699MetMet: 0.699 ± 0.008
1.015MetAsn: 1.015 ± 0.009
1.14MetPro: 1.14 ± 0.009
0.963MetGln: 0.963 ± 0.01
1.303MetArg: 1.303 ± 0.01
1.767MetSer: 1.767 ± 0.012
1.085MetThr: 1.085 ± 0.009
1.688MetVal: 1.688 ± 0.012
0.296MetTrp: 0.296 ± 0.006
0.604MetTyr: 0.604 ± 0.008
0.0MetXaa: 0.0 ± 0.0
Asn
2.64AsnAla: 2.64 ± 0.015
0.921AsnCys: 0.921 ± 0.01
1.972AsnAsp: 1.972 ± 0.012
2.409AsnGlu: 2.409 ± 0.017
1.788AsnPhe: 1.788 ± 0.014
3.205AsnGly: 3.205 ± 0.018
1.091AsnHis: 1.091 ± 0.01
2.38AsnIle: 2.38 ± 0.015
2.138AsnLys: 2.138 ± 0.013
4.837AsnLeu: 4.837 ± 0.039
1.091AsnMet: 1.091 ± 0.01
2.141AsnAsn: 2.141 ± 0.024
2.45AsnPro: 2.45 ± 0.018
1.615AsnGln: 1.615 ± 0.014
2.147AsnArg: 2.147 ± 0.014
3.757AsnSer: 3.757 ± 0.021
1.915AsnThr: 1.915 ± 0.013
2.607AsnVal: 2.607 ± 0.016
0.565AsnTrp: 0.565 ± 0.007
1.231AsnTyr: 1.231 ± 0.012
0.0AsnXaa: 0.0 ± 0.0
Pro
3.014ProAla: 3.014 ± 0.021
0.841ProCys: 0.841 ± 0.009
2.536ProAsp: 2.536 ± 0.017
3.027ProGlu: 3.027 ± 0.02
2.141ProPhe: 2.141 ± 0.015
2.671ProGly: 2.671 ± 0.019
1.261ProHis: 1.261 ± 0.011
2.583ProIle: 2.583 ± 0.017
2.735ProLys: 2.735 ± 0.021
4.601ProLeu: 4.601 ± 0.024
1.05ProMet: 1.05 ± 0.011
2.373ProAsn: 2.373 ± 0.016
4.12ProPro: 4.12 ± 0.06
1.865ProGln: 1.865 ± 0.016
2.432ProArg: 2.432 ± 0.019
5.573ProSer: 5.573 ± 0.029
2.856ProThr: 2.856 ± 0.019
2.966ProVal: 2.966 ± 0.02
0.614ProTrp: 0.614 ± 0.008
1.306ProTyr: 1.306 ± 0.014
0.0ProXaa: 0.0 ± 0.0
Gln
2.373GlnAla: 2.373 ± 0.016
0.597GlnCys: 0.597 ± 0.007
1.587GlnAsp: 1.587 ± 0.011
2.418GlnGlu: 2.418 ± 0.018
1.378GlnPhe: 1.378 ± 0.012
2.202GlnGly: 2.202 ± 0.017
0.928GlnHis: 0.928 ± 0.01
2.014GlnIle: 2.014 ± 0.015
2.216GlnLys: 2.216 ± 0.017
3.732GlnLeu: 3.732 ± 0.022
1.057GlnMet: 1.057 ± 0.011
1.689GlnAsn: 1.689 ± 0.014
1.679GlnPro: 1.679 ± 0.016
2.051GlnGln: 2.051 ± 0.031
2.163GlnArg: 2.163 ± 0.014
2.811GlnSer: 2.811 ± 0.019
1.745GlnThr: 1.745 ± 0.012
2.245GlnVal: 2.245 ± 0.014
0.463GlnTrp: 0.463 ± 0.007
0.915GlnTyr: 0.915 ± 0.009
0.0GlnXaa: 0.0 ± 0.0
Arg
3.455ArgAla: 3.455 ± 0.027
1.046ArgCys: 1.046 ± 0.011
2.76ArgAsp: 2.76 ± 0.017
3.547ArgGlu: 3.547 ± 0.028
2.31ArgPhe: 2.31 ± 0.015
3.453ArgGly: 3.453 ± 0.047
1.32ArgHis: 1.32 ± 0.011
3.003ArgIle: 3.003 ± 0.017
3.662ArgLys: 3.662 ± 0.024
5.316ArgLeu: 5.316 ± 0.023
1.42ArgMet: 1.42 ± 0.011
2.472ArgAsn: 2.472 ± 0.015
2.555ArgPro: 2.555 ± 0.019
1.853ArgGln: 1.853 ± 0.016
4.257ArgArg: 4.257 ± 0.041
4.558ArgSer: 4.558 ± 0.028
2.521ArgThr: 2.521 ± 0.018
3.382ArgVal: 3.382 ± 0.02
0.831ArgTrp: 0.831 ± 0.009
1.429ArgTyr: 1.429 ± 0.012
0.0ArgXaa: 0.0 ± 0.0
Ser
5.352SerAla: 5.352 ± 0.024
1.718SerCys: 1.718 ± 0.012
4.352SerAsp: 4.352 ± 0.021
4.537SerGlu: 4.537 ± 0.026
4.102SerPhe: 4.102 ± 0.022
5.96SerGly: 5.96 ± 0.027
2.104SerHis: 2.104 ± 0.013
4.835SerIle: 4.835 ± 0.022
4.661SerLys: 4.661 ± 0.021
9.243SerLeu: 9.243 ± 0.039
2.204SerMet: 2.204 ± 0.014
4.12SerAsn: 4.12 ± 0.021
4.779SerPro: 4.779 ± 0.037
2.986SerGln: 2.986 ± 0.016
4.45SerArg: 4.45 ± 0.022
11.207SerSer: 11.207 ± 0.056
4.735SerThr: 4.735 ± 0.022
5.086SerVal: 5.086 ± 0.023
1.227SerTrp: 1.227 ± 0.01
2.3SerTyr: 2.3 ± 0.015
0.0SerXaa: 0.0 ± 0.0
Thr
3.413ThrAla: 3.413 ± 0.019
0.964ThrCys: 0.964 ± 0.01
2.283ThrAsp: 2.283 ± 0.014
2.653ThrGlu: 2.653 ± 0.017
2.03ThrPhe: 2.03 ± 0.016
3.373ThrGly: 3.373 ± 0.023
1.129ThrHis: 1.129 ± 0.01
2.818ThrIle: 2.818 ± 0.016
2.463ThrLys: 2.463 ± 0.016
4.712ThrLeu: 4.712 ± 0.023
1.193ThrMet: 1.193 ± 0.01
2.109ThrAsn: 2.109 ± 0.016
2.574ThrPro: 2.574 ± 0.02
1.593ThrGln: 1.593 ± 0.011
2.409ThrArg: 2.409 ± 0.016
4.543ThrSer: 4.543 ± 0.023
2.925ThrThr: 2.925 ± 0.018
3.28ThrVal: 3.28 ± 0.019
0.656ThrTrp: 0.656 ± 0.008
1.342ThrTyr: 1.342 ± 0.012
0.0ThrXaa: 0.0 ± 0.0
Val
4.809ValAla: 4.809 ± 0.023
1.115ValCys: 1.115 ± 0.01
3.642ValAsp: 3.642 ± 0.021
4.317ValGlu: 4.317 ± 0.023
2.69ValPhe: 2.69 ± 0.017
4.367ValGly: 4.367 ± 0.021
1.466ValHis: 1.466 ± 0.011
3.322ValIle: 3.322 ± 0.018
3.551ValLys: 3.551 ± 0.018
6.317ValLeu: 6.317 ± 0.028
1.539ValMet: 1.539 ± 0.013
2.329ValAsn: 2.329 ± 0.016
3.143ValPro: 3.143 ± 0.018
2.151ValGln: 2.151 ± 0.016
3.159ValArg: 3.159 ± 0.017
5.163ValSer: 5.163 ± 0.021
3.099ValThr: 3.099 ± 0.02
4.855ValVal: 4.855 ± 0.023
0.812ValTrp: 0.812 ± 0.009
1.813ValTyr: 1.813 ± 0.014
0.0ValXaa: 0.0 ± 0.0
Trp
0.861TrpAla: 0.861 ± 0.011
0.239TrpCys: 0.239 ± 0.005
0.719TrpAsp: 0.719 ± 0.008
0.799TrpGlu: 0.799 ± 0.009
0.537TrpPhe: 0.537 ± 0.007
0.769TrpGly: 0.769 ± 0.009
0.309TrpHis: 0.309 ± 0.005
0.738TrpIle: 0.738 ± 0.007
0.965TrpLys: 0.965 ± 0.01
1.247TrpLeu: 1.247 ± 0.013
0.376TrpMet: 0.376 ± 0.006
0.737TrpAsn: 0.737 ± 0.01
0.514TrpPro: 0.514 ± 0.006
0.449TrpGln: 0.449 ± 0.007
0.874TrpArg: 0.874 ± 0.01
1.002TrpSer: 1.002 ± 0.01
0.662TrpThr: 0.662 ± 0.008
0.894TrpVal: 0.894 ± 0.009
0.263TrpTrp: 0.263 ± 0.006
0.346TrpTyr: 0.346 ± 0.006
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.706TyrAla: 1.706 ± 0.014
0.636TyrCys: 0.636 ± 0.008
1.441TyrAsp: 1.441 ± 0.011
1.517TyrGlu: 1.517 ± 0.012
1.255TyrPhe: 1.255 ± 0.012
2.099TyrGly: 2.099 ± 0.018
0.699TyrHis: 0.699 ± 0.008
1.436TyrIle: 1.436 ± 0.011
1.444TyrLys: 1.444 ± 0.012
2.797TyrLeu: 2.797 ± 0.019
0.765TyrMet: 0.765 ± 0.007
1.275TyrAsn: 1.275 ± 0.011
1.243TyrPro: 1.243 ± 0.011
0.896TyrGln: 0.896 ± 0.009
1.469TyrArg: 1.469 ± 0.013
2.214TyrSer: 2.214 ± 0.015
1.246TyrThr: 1.246 ± 0.012
1.675TyrVal: 1.675 ± 0.014
0.416TyrTrp: 0.416 ± 0.006
0.934TyrTyr: 0.934 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.008XaaXaa: 0.008 ± 0.004
Statistics based on 26414 proteins (11631408 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski