Amino acid dipepetide frequency for Sweet potato leaf curl Hubei virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.014AlaAla: 6.014 ± 2.831
1.718AlaCys: 1.718 ± 1.215
0.859AlaAsp: 0.859 ± 0.973
0.859AlaGlu: 0.859 ± 0.635
0.859AlaPhe: 0.859 ± 0.932
2.577AlaGly: 2.577 ± 1.245
1.718AlaHis: 1.718 ± 0.752
2.577AlaIle: 2.577 ± 1.309
5.155AlaLys: 5.155 ± 2.028
5.155AlaLeu: 5.155 ± 1.693
0.859AlaMet: 0.859 ± 0.782
3.436AlaAsn: 3.436 ± 1.789
5.155AlaPro: 5.155 ± 1.102
1.718AlaGln: 1.718 ± 0.752
4.296AlaArg: 4.296 ± 1.838
5.155AlaSer: 5.155 ± 1.769
0.859AlaThr: 0.859 ± 0.782
2.577AlaVal: 2.577 ± 1.549
0.859AlaTrp: 0.859 ± 0.635
1.718AlaTyr: 1.718 ± 0.752
0.0AlaXaa: 0.0 ± 0.0
Cys
0.859CysAla: 0.859 ± 0.973
1.718CysCys: 1.718 ± 1.945
1.718CysAsp: 1.718 ± 1.299
0.859CysGlu: 0.859 ± 0.973
0.859CysPhe: 0.859 ± 0.91
3.436CysGly: 3.436 ± 1.848
0.0CysHis: 0.0 ± 0.0
0.859CysIle: 0.859 ± 0.782
4.296CysLys: 4.296 ± 1.041
0.0CysLeu: 0.0 ± 0.0
0.859CysMet: 0.859 ± 0.973
0.859CysAsn: 0.859 ± 0.635
0.859CysPro: 0.859 ± 0.973
0.0CysGln: 0.0 ± 0.0
1.718CysArg: 1.718 ± 1.026
1.718CysSer: 1.718 ± 1.028
3.436CysThr: 3.436 ± 3.729
1.718CysVal: 1.718 ± 1.563
0.0CysTrp: 0.0 ± 0.0
0.859CysTyr: 0.859 ± 0.932
0.0CysXaa: 0.0 ± 0.0
Asp
1.718AspAla: 1.718 ± 1.271
2.577AspCys: 2.577 ± 2.081
2.577AspAsp: 2.577 ± 0.937
0.0AspGlu: 0.0 ± 0.0
2.577AspPhe: 2.577 ± 0.914
2.577AspGly: 2.577 ± 1.906
1.718AspHis: 1.718 ± 1.049
1.718AspIle: 1.718 ± 0.984
1.718AspLys: 1.718 ± 1.028
5.155AspLeu: 5.155 ± 0.784
0.859AspMet: 0.859 ± 0.582
3.436AspAsn: 3.436 ± 1.739
2.577AspPro: 2.577 ± 1.008
0.0AspGln: 0.0 ± 0.0
3.436AspArg: 3.436 ± 2.416
5.155AspSer: 5.155 ± 2.798
0.859AspThr: 0.859 ± 0.635
4.296AspVal: 4.296 ± 1.041
3.436AspTrp: 3.436 ± 1.173
1.718AspTyr: 1.718 ± 1.049
0.0AspXaa: 0.0 ± 0.0
Glu
3.436GluAla: 3.436 ± 1.218
1.718GluCys: 1.718 ± 1.215
3.436GluAsp: 3.436 ± 1.336
6.014GluGlu: 6.014 ± 2.028
2.577GluPhe: 2.577 ± 0.762
4.296GluGly: 4.296 ± 1.889
0.859GluHis: 0.859 ± 0.932
0.0GluIle: 0.0 ± 0.0
0.859GluLys: 0.859 ± 0.635
5.155GluLeu: 5.155 ± 2.012
0.0GluMet: 0.0 ± 0.0
3.436GluAsn: 3.436 ± 1.503
3.436GluPro: 3.436 ± 1.842
1.718GluGln: 1.718 ± 1.164
3.436GluArg: 3.436 ± 1.437
2.577GluSer: 2.577 ± 1.102
4.296GluThr: 4.296 ± 1.813
1.718GluVal: 1.718 ± 1.028
0.859GluTrp: 0.859 ± 0.635
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.859PheAla: 0.859 ± 0.635
0.859PheCys: 0.859 ± 0.932
2.577PheAsp: 2.577 ± 0.762
0.859PheGlu: 0.859 ± 0.635
2.577PhePhe: 2.577 ± 0.937
1.718PheGly: 1.718 ± 1.026
3.436PheHis: 3.436 ± 1.0
2.577PheIle: 2.577 ± 1.854
2.577PheLys: 2.577 ± 1.396
3.436PheLeu: 3.436 ± 1.813
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.859PhePro: 0.859 ± 0.635
2.577PheGln: 2.577 ± 1.152
3.436PheArg: 3.436 ± 1.322
4.296PheSer: 4.296 ± 2.35
4.296PheThr: 4.296 ± 1.345
2.577PheVal: 2.577 ± 0.762
0.859PheTrp: 0.859 ± 0.782
1.718PheTyr: 1.718 ± 0.752
0.0PheXaa: 0.0 ± 0.0
Gly
5.155GlyAla: 5.155 ± 2.052
2.577GlyCys: 2.577 ± 1.825
1.718GlyAsp: 1.718 ± 0.752
3.436GlyGlu: 3.436 ± 1.319
3.436GlyPhe: 3.436 ± 1.397
3.436GlyGly: 3.436 ± 1.503
2.577GlyHis: 2.577 ± 1.245
0.859GlyIle: 0.859 ± 0.635
6.873GlyLys: 6.873 ± 1.899
2.577GlyLeu: 2.577 ± 1.396
0.0GlyMet: 0.0 ± 0.0
1.718GlyAsn: 1.718 ± 1.159
3.436GlyPro: 3.436 ± 1.503
1.718GlyGln: 1.718 ± 0.901
2.577GlyArg: 2.577 ± 1.689
5.155GlySer: 5.155 ± 1.778
3.436GlyThr: 3.436 ± 1.482
0.859GlyVal: 0.859 ± 0.932
0.0GlyTrp: 0.0 ± 0.0
0.859GlyTyr: 0.859 ± 0.885
0.0GlyXaa: 0.0 ± 0.0
His
0.859HisAla: 0.859 ± 0.782
0.0HisCys: 0.0 ± 0.0
1.718HisAsp: 1.718 ± 1.335
3.436HisGlu: 3.436 ± 1.848
1.718HisPhe: 1.718 ± 1.271
3.436HisGly: 3.436 ± 1.397
0.0HisHis: 0.0 ± 0.0
1.718HisIle: 1.718 ± 1.821
2.577HisLys: 2.577 ± 1.396
2.577HisLeu: 2.577 ± 1.309
1.718HisMet: 1.718 ± 1.563
1.718HisAsn: 1.718 ± 1.271
3.436HisPro: 3.436 ± 1.458
0.0HisGln: 0.0 ± 0.0
3.436HisArg: 3.436 ± 1.842
1.718HisSer: 1.718 ± 1.77
2.577HisThr: 2.577 ± 1.223
2.577HisVal: 2.577 ± 0.914
0.0HisTrp: 0.0 ± 0.0
1.718HisTyr: 1.718 ± 0.901
0.0HisXaa: 0.0 ± 0.0
Ile
0.859IleAla: 0.859 ± 0.782
1.718IleCys: 1.718 ± 0.919
4.296IleAsp: 4.296 ± 2.171
1.718IleGlu: 1.718 ± 1.271
3.436IlePhe: 3.436 ± 1.309
2.577IleGly: 2.577 ± 1.689
4.296IleHis: 4.296 ± 3.68
3.436IleIle: 3.436 ± 0.952
3.436IleLys: 3.436 ± 1.104
1.718IleLeu: 1.718 ± 0.901
0.859IleMet: 0.859 ± 0.885
0.859IleAsn: 0.859 ± 0.635
3.436IlePro: 3.436 ± 1.686
4.296IleGln: 4.296 ± 1.724
4.296IleArg: 4.296 ± 1.813
3.436IleSer: 3.436 ± 2.13
2.577IleThr: 2.577 ± 1.26
1.718IleVal: 1.718 ± 0.752
1.718IleTrp: 1.718 ± 1.275
0.859IleTyr: 0.859 ± 0.782
0.0IleXaa: 0.0 ± 0.0
Lys
1.718LysAla: 1.718 ± 0.752
0.0LysCys: 0.0 ± 0.0
5.155LysAsp: 5.155 ± 1.512
6.873LysGlu: 6.873 ± 1.835
2.577LysPhe: 2.577 ± 1.429
1.718LysGly: 1.718 ± 0.752
1.718LysHis: 1.718 ± 0.901
2.577LysIle: 2.577 ± 1.125
3.436LysLys: 3.436 ± 1.687
0.859LysLeu: 0.859 ± 0.973
1.718LysMet: 1.718 ± 1.159
5.155LysAsn: 5.155 ± 1.693
1.718LysPro: 1.718 ± 0.901
1.718LysGln: 1.718 ± 1.299
4.296LysArg: 4.296 ± 2.589
6.873LysSer: 6.873 ± 2.036
1.718LysThr: 1.718 ± 0.901
4.296LysVal: 4.296 ± 1.929
0.859LysTrp: 0.859 ± 0.885
4.296LysTyr: 4.296 ± 1.718
0.0LysXaa: 0.0 ± 0.0
Leu
3.436LeuAla: 3.436 ± 1.041
1.718LeuCys: 1.718 ± 1.271
3.436LeuAsp: 3.436 ± 1.437
2.577LeuGlu: 2.577 ± 1.152
0.859LeuPhe: 0.859 ± 0.782
3.436LeuGly: 3.436 ± 1.218
4.296LeuHis: 4.296 ± 1.941
5.155LeuIle: 5.155 ± 1.827
4.296LeuLys: 4.296 ± 1.998
6.014LeuLeu: 6.014 ± 2.402
0.859LeuMet: 0.859 ± 0.91
5.155LeuAsn: 5.155 ± 1.912
2.577LeuPro: 2.577 ± 1.114
5.155LeuGln: 5.155 ± 2.075
6.873LeuArg: 6.873 ± 2.613
11.168LeuSer: 11.168 ± 3.581
6.014LeuThr: 6.014 ± 2.459
4.296LeuVal: 4.296 ± 1.642
0.859LeuTrp: 0.859 ± 0.973
4.296LeuTyr: 4.296 ± 1.837
0.0LeuXaa: 0.0 ± 0.0
Met
0.859MetAla: 0.859 ± 0.885
0.0MetCys: 0.0 ± 0.0
3.436MetAsp: 3.436 ± 1.739
1.718MetGlu: 1.718 ± 1.245
0.859MetPhe: 0.859 ± 0.782
1.718MetGly: 1.718 ± 1.159
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.859MetLys: 0.859 ± 0.885
2.577MetLeu: 2.577 ± 1.364
0.0MetMet: 0.0 ± 0.0
0.859MetAsn: 0.859 ± 0.782
0.859MetPro: 0.859 ± 0.635
0.859MetGln: 0.859 ± 0.932
0.0MetArg: 0.0 ± 0.0
3.436MetSer: 3.436 ± 1.041
0.859MetThr: 0.859 ± 0.91
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.859MetTyr: 0.859 ± 0.885
0.0MetXaa: 0.0 ± 0.0
Asn
5.155AsnAla: 5.155 ± 1.66
0.859AsnCys: 0.859 ± 0.635
1.718AsnAsp: 1.718 ± 1.271
0.859AsnGlu: 0.859 ± 0.782
2.577AsnPhe: 2.577 ± 0.762
0.859AsnGly: 0.859 ± 0.91
2.577AsnHis: 2.577 ± 1.542
4.296AsnIle: 4.296 ± 1.488
1.718AsnLys: 1.718 ± 0.752
2.577AsnLeu: 2.577 ± 1.309
0.859AsnMet: 0.859 ± 0.719
4.296AsnAsn: 4.296 ± 1.538
4.296AsnPro: 4.296 ± 0.951
1.718AsnGln: 1.718 ± 1.159
1.718AsnArg: 1.718 ± 1.271
2.577AsnSer: 2.577 ± 2.731
0.0AsnThr: 0.0 ± 0.0
3.436AsnVal: 3.436 ± 1.458
0.0AsnTrp: 0.0 ± 0.0
3.436AsnTyr: 3.436 ± 1.924
0.0AsnXaa: 0.0 ± 0.0
Pro
4.296ProAla: 4.296 ± 1.973
0.859ProCys: 0.859 ± 0.782
1.718ProAsp: 1.718 ± 1.864
4.296ProGlu: 4.296 ± 1.889
1.718ProPhe: 1.718 ± 0.919
2.577ProGly: 2.577 ± 1.114
3.436ProHis: 3.436 ± 1.701
0.859ProIle: 0.859 ± 0.932
2.577ProLys: 2.577 ± 1.102
6.014ProLeu: 6.014 ± 2.639
3.436ProMet: 3.436 ± 1.289
3.436ProAsn: 3.436 ± 1.0
4.296ProPro: 4.296 ± 2.848
5.155ProGln: 5.155 ± 2.034
4.296ProArg: 4.296 ± 1.041
3.436ProSer: 3.436 ± 1.924
3.436ProThr: 3.436 ± 1.803
6.014ProVal: 6.014 ± 1.908
0.0ProTrp: 0.0 ± 0.0
2.577ProTyr: 2.577 ± 2.345
0.0ProXaa: 0.0 ± 0.0
Gln
2.577GlnAla: 2.577 ± 1.755
1.718GlnCys: 1.718 ± 1.271
0.859GlnAsp: 0.859 ± 0.782
0.0GlnGlu: 0.0 ± 0.0
3.436GlnPhe: 3.436 ± 1.475
2.577GlnGly: 2.577 ± 1.266
0.859GlnHis: 0.859 ± 0.91
3.436GlnIle: 3.436 ± 1.841
2.577GlnLys: 2.577 ± 1.236
7.732GlnLeu: 7.732 ± 3.663
0.0GlnMet: 0.0 ± 0.0
0.859GlnAsn: 0.859 ± 0.635
1.718GlnPro: 1.718 ± 1.205
2.577GlnGln: 2.577 ± 1.429
1.718GlnArg: 1.718 ± 1.205
4.296GlnSer: 4.296 ± 1.093
3.436GlnThr: 3.436 ± 1.813
1.718GlnVal: 1.718 ± 1.563
0.859GlnTrp: 0.859 ± 0.635
0.859GlnTyr: 0.859 ± 0.932
0.0GlnXaa: 0.0 ± 0.0
Arg
1.718ArgAla: 1.718 ± 0.984
0.859ArgCys: 0.859 ± 0.973
3.436ArgAsp: 3.436 ± 1.482
4.296ArgGlu: 4.296 ± 1.924
3.436ArgPhe: 3.436 ± 1.503
6.014ArgGly: 6.014 ± 1.849
0.859ArgHis: 0.859 ± 0.973
6.873ArgIle: 6.873 ± 2.471
3.436ArgLys: 3.436 ± 1.356
6.873ArgLeu: 6.873 ± 2.3
0.859ArgMet: 0.859 ± 0.91
0.0ArgAsn: 0.0 ± 0.0
4.296ArgPro: 4.296 ± 1.488
0.859ArgGln: 0.859 ± 0.932
6.014ArgArg: 6.014 ± 3.73
6.873ArgSer: 6.873 ± 2.942
6.014ArgThr: 6.014 ± 2.725
5.155ArgVal: 5.155 ± 1.808
0.0ArgTrp: 0.0 ± 0.0
0.859ArgTyr: 0.859 ± 0.782
0.0ArgXaa: 0.0 ± 0.0
Ser
6.014SerAla: 6.014 ± 1.976
2.577SerCys: 2.577 ± 1.935
3.436SerAsp: 3.436 ± 1.356
2.577SerGlu: 2.577 ± 1.114
1.718SerPhe: 1.718 ± 0.901
2.577SerGly: 2.577 ± 1.542
2.577SerHis: 2.577 ± 1.599
6.014SerIle: 6.014 ± 3.57
6.873SerLys: 6.873 ± 3.512
9.45SerLeu: 9.45 ± 3.202
1.718SerMet: 1.718 ± 1.274
6.014SerAsn: 6.014 ± 1.664
9.45SerPro: 9.45 ± 3.457
3.436SerGln: 3.436 ± 1.889
6.014SerArg: 6.014 ± 2.199
12.887SerSer: 12.887 ± 4.189
6.014SerThr: 6.014 ± 1.843
3.436SerVal: 3.436 ± 1.687
1.718SerTrp: 1.718 ± 1.299
3.436SerTyr: 3.436 ± 1.924
0.0SerXaa: 0.0 ± 0.0
Thr
3.436ThrAla: 3.436 ± 1.397
1.718ThrCys: 1.718 ± 1.205
4.296ThrAsp: 4.296 ± 2.132
2.577ThrGlu: 2.577 ± 1.854
4.296ThrPhe: 4.296 ± 3.197
2.577ThrGly: 2.577 ± 1.701
4.296ThrHis: 4.296 ± 1.617
1.718ThrIle: 1.718 ± 1.026
1.718ThrLys: 1.718 ± 1.205
5.155ThrLeu: 5.155 ± 2.499
0.0ThrMet: 0.0 ± 0.0
0.859ThrAsn: 0.859 ± 0.782
4.296ThrPro: 4.296 ± 1.778
1.718ThrGln: 1.718 ± 1.821
3.436ThrArg: 3.436 ± 1.356
6.014ThrSer: 6.014 ± 2.522
0.859ThrThr: 0.859 ± 0.782
1.718ThrVal: 1.718 ± 0.752
0.859ThrTrp: 0.859 ± 0.932
2.577ThrTyr: 2.577 ± 1.152
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
3.436ValCys: 3.436 ± 2.327
0.0ValAsp: 0.0 ± 0.0
1.718ValGlu: 1.718 ± 1.275
0.0ValPhe: 0.0 ± 0.0
1.718ValGly: 1.718 ± 1.563
1.718ValHis: 1.718 ± 1.026
3.436ValIle: 3.436 ± 1.471
3.436ValLys: 3.436 ± 1.173
6.014ValLeu: 6.014 ± 1.916
1.718ValMet: 1.718 ± 1.77
1.718ValAsn: 1.718 ± 1.271
6.014ValPro: 6.014 ± 2.7
4.296ValGln: 4.296 ± 1.497
5.155ValArg: 5.155 ± 3.455
4.296ValSer: 4.296 ± 1.33
2.577ValThr: 2.577 ± 1.599
0.0ValVal: 0.0 ± 0.0
1.718ValTrp: 1.718 ± 0.752
2.577ValTyr: 2.577 ± 1.396
0.0ValXaa: 0.0 ± 0.0
Trp
2.577TrpAla: 2.577 ± 1.429
0.0TrpCys: 0.0 ± 0.0
0.859TrpAsp: 0.859 ± 0.973
0.859TrpGlu: 0.859 ± 0.932
0.859TrpPhe: 0.859 ± 0.932
0.859TrpGly: 0.859 ± 0.635
0.0TrpHis: 0.0 ± 0.0
1.718TrpIle: 1.718 ± 0.984
0.0TrpLys: 0.0 ± 0.0
0.859TrpLeu: 0.859 ± 0.782
0.859TrpMet: 0.859 ± 0.782
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.718TrpGln: 1.718 ± 0.919
0.859TrpArg: 0.859 ± 0.885
0.859TrpSer: 0.859 ± 0.91
0.859TrpThr: 0.859 ± 0.635
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.859TrpTyr: 0.859 ± 0.635
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.577TyrAla: 2.577 ± 1.396
0.0TyrCys: 0.0 ± 0.0
0.859TyrAsp: 0.859 ± 0.782
4.296TyrGlu: 4.296 ± 2.082
1.718TyrPhe: 1.718 ± 0.752
1.718TyrGly: 1.718 ± 0.901
0.0TyrHis: 0.0 ± 0.0
1.718TyrIle: 1.718 ± 0.919
0.859TyrLys: 0.859 ± 0.635
2.577TyrLeu: 2.577 ± 1.906
1.718TyrMet: 1.718 ± 1.305
1.718TyrAsn: 1.718 ± 0.752
1.718TyrPro: 1.718 ± 0.901
2.577TyrGln: 2.577 ± 0.762
1.718TyrArg: 1.718 ± 1.026
6.873TyrSer: 6.873 ± 2.354
0.0TyrThr: 0.0 ± 0.0
3.436TyrVal: 3.436 ± 1.482
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1165 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski