Amino acid dipepetide frequency for Circovirus-like genome DCCV-3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.11AlaAla: 3.11 ± 2.692
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
1.555AlaGlu: 1.555 ± 1.154
3.11AlaPhe: 3.11 ± 0.678
6.221AlaGly: 6.221 ± 1.356
3.11AlaHis: 3.11 ± 0.678
0.0AlaIle: 0.0 ± 0.0
7.776AlaLys: 7.776 ± 1.77
4.666AlaLeu: 4.666 ± 1.331
0.0AlaMet: 0.0 ± 0.0
4.666AlaAsn: 4.666 ± 1.792
1.555AlaPro: 1.555 ± 1.346
3.11AlaGln: 3.11 ± 2.692
3.11AlaArg: 3.11 ± 0.678
0.0AlaSer: 0.0 ± 0.0
4.666AlaThr: 4.666 ± 1.792
0.0AlaVal: 0.0 ± 0.0
1.555AlaTrp: 1.555 ± 1.346
1.555AlaTyr: 1.555 ± 1.346
0.0AlaXaa: 0.0 ± 0.0
Cys
3.11CysAla: 3.11 ± 2.309
0.0CysCys: 0.0 ± 0.0
1.555CysAsp: 1.555 ± 1.154
1.555CysGlu: 1.555 ± 1.346
3.11CysPhe: 3.11 ± 2.309
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
3.11CysPro: 3.11 ± 0.678
0.0CysGln: 0.0 ± 0.0
1.555CysArg: 1.555 ± 1.154
1.555CysSer: 1.555 ± 1.154
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.555CysTrp: 1.555 ± 1.8
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.555AspAla: 1.555 ± 1.154
0.0AspCys: 0.0 ± 0.0
6.221AspAsp: 6.221 ± 2.398
3.11AspGlu: 3.11 ± 1.573
1.555AspPhe: 1.555 ± 1.154
3.11AspGly: 3.11 ± 2.309
0.0AspHis: 0.0 ± 0.0
10.886AspIle: 10.886 ± 2.929
1.555AspLys: 1.555 ± 1.154
4.666AspLeu: 4.666 ± 1.792
1.555AspMet: 1.555 ± 1.8
3.11AspAsn: 3.11 ± 2.309
3.11AspPro: 3.11 ± 2.692
3.11AspGln: 3.11 ± 0.678
3.11AspArg: 3.11 ± 0.678
0.0AspSer: 0.0 ± 0.0
1.555AspThr: 1.555 ± 1.346
1.555AspVal: 1.555 ± 1.346
0.0AspTrp: 0.0 ± 0.0
1.555AspTyr: 1.555 ± 1.154
0.0AspXaa: 0.0 ± 0.0
Glu
1.555GluAla: 1.555 ± 1.346
1.555GluCys: 1.555 ± 1.154
3.11GluAsp: 3.11 ± 2.309
3.11GluGlu: 3.11 ± 2.309
1.555GluPhe: 1.555 ± 1.346
0.0GluGly: 0.0 ± 0.0
3.11GluHis: 3.11 ± 3.6
4.666GluIle: 4.666 ± 1.268
1.555GluLys: 1.555 ± 1.154
1.555GluLeu: 1.555 ± 1.154
6.221GluMet: 6.221 ± 2.99
4.666GluAsn: 4.666 ± 3.463
1.555GluPro: 1.555 ± 1.154
0.0GluGln: 0.0 ± 0.0
6.221GluArg: 6.221 ± 2.09
3.11GluSer: 3.11 ± 1.573
6.221GluThr: 6.221 ± 3.146
4.666GluVal: 4.666 ± 2.091
0.0GluTrp: 0.0 ± 0.0
6.221GluTyr: 6.221 ± 3.04
0.0GluXaa: 0.0 ± 0.0
Phe
4.666PheAla: 4.666 ± 1.792
0.0PheCys: 0.0 ± 0.0
3.11PheAsp: 3.11 ± 2.692
0.0PheGlu: 0.0 ± 0.0
1.555PhePhe: 1.555 ± 1.346
1.555PheGly: 1.555 ± 1.346
1.555PheHis: 1.555 ± 1.154
0.0PheIle: 0.0 ± 0.0
1.555PheLys: 1.555 ± 1.154
1.555PheLeu: 1.555 ± 1.346
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
1.555PheArg: 1.555 ± 1.346
1.555PheSer: 1.555 ± 1.154
3.11PheThr: 3.11 ± 0.678
1.555PheVal: 1.555 ± 1.346
1.555PheTrp: 1.555 ± 1.154
1.555PheTyr: 1.555 ± 1.154
0.0PheXaa: 0.0 ± 0.0
Gly
1.555GlyAla: 1.555 ± 1.346
1.555GlyCys: 1.555 ± 1.154
3.11GlyAsp: 3.11 ± 2.309
4.666GlyGlu: 4.666 ± 3.463
1.555GlyPhe: 1.555 ± 1.346
4.666GlyGly: 4.666 ± 1.792
3.11GlyHis: 3.11 ± 0.678
6.221GlyIle: 6.221 ± 2.398
1.555GlyLys: 1.555 ± 1.154
1.555GlyLeu: 1.555 ± 1.346
1.555GlyMet: 1.555 ± 1.154
3.11GlyAsn: 3.11 ± 2.309
0.0GlyPro: 0.0 ± 0.0
3.11GlyGln: 3.11 ± 2.249
1.555GlyArg: 1.555 ± 1.154
4.666GlySer: 4.666 ± 1.331
3.11GlyThr: 3.11 ± 0.678
4.666GlyVal: 4.666 ± 1.792
1.555GlyTrp: 1.555 ± 1.346
6.221GlyTyr: 6.221 ± 2.398
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.555HisAsp: 1.555 ± 1.346
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
4.666HisIle: 4.666 ± 2.091
1.555HisLys: 1.555 ± 1.154
1.555HisLeu: 1.555 ± 1.154
1.555HisMet: 1.555 ± 1.8
4.666HisAsn: 4.666 ± 3.178
0.0HisPro: 0.0 ± 0.0
1.555HisGln: 1.555 ± 1.346
1.555HisArg: 1.555 ± 1.346
4.666HisSer: 4.666 ± 1.268
4.666HisThr: 4.666 ± 3.463
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.555IleAla: 1.555 ± 1.154
0.0IleCys: 0.0 ± 0.0
1.555IleAsp: 1.555 ± 1.154
6.221IleGlu: 6.221 ± 4.617
1.555IlePhe: 1.555 ± 1.346
4.666IleGly: 4.666 ± 1.268
1.555IleHis: 1.555 ± 1.154
0.0IleIle: 0.0 ± 0.0
6.221IleLys: 6.221 ± 2.99
6.221IleLeu: 6.221 ± 4.617
1.555IleMet: 1.555 ± 1.346
3.11IleAsn: 3.11 ± 2.309
1.555IlePro: 1.555 ± 1.346
6.221IleGln: 6.221 ± 2.398
1.555IleArg: 1.555 ± 1.346
4.666IleSer: 4.666 ± 1.268
7.776IleThr: 7.776 ± 1.644
6.221IleVal: 6.221 ± 2.99
0.0IleTrp: 0.0 ± 0.0
9.331IleTyr: 9.331 ± 4.183
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
1.555LysCys: 1.555 ± 1.154
3.11LysAsp: 3.11 ± 2.309
3.11LysGlu: 3.11 ± 2.309
0.0LysPhe: 0.0 ± 0.0
4.666LysGly: 4.666 ± 1.331
1.555LysHis: 1.555 ± 1.154
4.666LysIle: 4.666 ± 3.463
4.666LysLys: 4.666 ± 1.331
7.776LysLeu: 7.776 ± 3.52
0.0LysMet: 0.0 ± 0.0
1.555LysAsn: 1.555 ± 1.8
3.11LysPro: 3.11 ± 2.692
1.555LysGln: 1.555 ± 1.8
4.666LysArg: 4.666 ± 2.091
4.666LysSer: 4.666 ± 3.241
6.221LysThr: 6.221 ± 3.04
3.11LysVal: 3.11 ± 0.678
0.0LysTrp: 0.0 ± 0.0
3.11LysTyr: 3.11 ± 2.309
0.0LysXaa: 0.0 ± 0.0
Leu
4.666LeuAla: 4.666 ± 3.463
1.555LeuCys: 1.555 ± 1.154
4.666LeuAsp: 4.666 ± 3.463
3.11LeuGlu: 3.11 ± 2.309
0.0LeuPhe: 0.0 ± 0.0
1.555LeuGly: 1.555 ± 1.346
0.0LeuHis: 0.0 ± 0.0
3.11LeuIle: 3.11 ± 2.309
7.776LeuLys: 7.776 ± 1.644
6.221LeuLeu: 6.221 ± 4.617
0.0LeuMet: 0.0 ± 0.0
3.11LeuAsn: 3.11 ± 2.309
4.666LeuPro: 4.666 ± 1.331
3.11LeuGln: 3.11 ± 2.249
4.666LeuArg: 4.666 ± 1.792
4.666LeuSer: 4.666 ± 1.268
1.555LeuThr: 1.555 ± 1.346
1.555LeuVal: 1.555 ± 1.346
1.555LeuTrp: 1.555 ± 1.8
3.11LeuTyr: 3.11 ± 2.692
0.0LeuXaa: 0.0 ± 0.0
Met
1.555MetAla: 1.555 ± 1.346
0.0MetCys: 0.0 ± 0.0
1.555MetAsp: 1.555 ± 1.8
4.666MetGlu: 4.666 ± 3.178
1.555MetPhe: 1.555 ± 1.346
0.0MetGly: 0.0 ± 0.0
1.555MetHis: 1.555 ± 1.154
3.11MetIle: 3.11 ± 0.678
1.555MetLys: 1.555 ± 1.154
4.666MetLeu: 4.666 ± 1.331
0.0MetMet: 0.0 ± 0.0
3.11MetAsn: 3.11 ± 2.309
3.11MetPro: 3.11 ± 1.573
0.0MetGln: 0.0 ± 0.0
3.11MetArg: 3.11 ± 2.692
0.0MetSer: 0.0 ± 0.0
1.555MetThr: 1.555 ± 1.8
0.0MetVal: 0.0 ± 0.0
1.555MetTrp: 1.555 ± 1.346
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.555AsnAla: 1.555 ± 1.346
3.11AsnCys: 3.11 ± 1.573
4.666AsnAsp: 4.666 ± 2.091
4.666AsnGlu: 4.666 ± 1.268
0.0AsnPhe: 0.0 ± 0.0
3.11AsnGly: 3.11 ± 0.678
1.555AsnHis: 1.555 ± 1.346
7.776AsnIle: 7.776 ± 4.021
3.11AsnLys: 3.11 ± 0.678
3.11AsnLeu: 3.11 ± 2.309
3.11AsnMet: 3.11 ± 1.573
3.11AsnAsn: 3.11 ± 2.309
0.0AsnPro: 0.0 ± 0.0
4.666AsnGln: 4.666 ± 3.463
4.666AsnArg: 4.666 ± 1.792
1.555AsnSer: 1.555 ± 1.154
1.555AsnThr: 1.555 ± 1.154
1.555AsnVal: 1.555 ± 1.8
3.11AsnTrp: 3.11 ± 0.678
6.221AsnTyr: 6.221 ± 2.99
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.555ProAsp: 1.555 ± 1.154
7.776ProGlu: 7.776 ± 2.521
0.0ProPhe: 0.0 ± 0.0
3.11ProGly: 3.11 ± 0.678
1.555ProHis: 1.555 ± 1.8
1.555ProIle: 1.555 ± 1.346
1.555ProLys: 1.555 ± 1.8
1.555ProLeu: 1.555 ± 1.346
4.666ProMet: 4.666 ± 2.05
4.666ProAsn: 4.666 ± 1.331
1.555ProPro: 1.555 ± 1.346
1.555ProGln: 1.555 ± 1.154
3.11ProArg: 3.11 ± 0.678
6.221ProSer: 6.221 ± 4.424
3.11ProThr: 3.11 ± 2.692
1.555ProVal: 1.555 ± 1.346
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.555GlnAla: 1.555 ± 1.346
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.555GlnGlu: 1.555 ± 1.346
1.555GlnPhe: 1.555 ± 1.346
3.11GlnGly: 3.11 ± 0.678
3.11GlnHis: 3.11 ± 2.309
3.11GlnIle: 3.11 ± 1.573
1.555GlnLys: 1.555 ± 1.154
1.555GlnLeu: 1.555 ± 1.346
0.0GlnMet: 0.0 ± 0.0
3.11GlnAsn: 3.11 ± 2.249
7.776GlnPro: 7.776 ± 1.644
0.0GlnGln: 0.0 ± 0.0
7.776GlnArg: 7.776 ± 4.021
1.555GlnSer: 1.555 ± 1.8
0.0GlnThr: 0.0 ± 0.0
9.331GlnVal: 9.331 ± 6.97
0.0GlnTrp: 0.0 ± 0.0
1.555GlnTyr: 1.555 ± 1.346
0.0GlnXaa: 0.0 ± 0.0
Arg
3.11ArgAla: 3.11 ± 2.309
1.555ArgCys: 1.555 ± 1.154
3.11ArgAsp: 3.11 ± 2.249
1.555ArgGlu: 1.555 ± 1.8
1.555ArgPhe: 1.555 ± 1.154
4.666ArgGly: 4.666 ± 1.331
0.0ArgHis: 0.0 ± 0.0
6.221ArgIle: 6.221 ± 1.356
3.11ArgLys: 3.11 ± 2.692
3.11ArgLeu: 3.11 ± 1.573
3.11ArgMet: 3.11 ± 2.692
6.221ArgAsn: 6.221 ± 1.356
3.11ArgPro: 3.11 ± 2.249
1.555ArgGln: 1.555 ± 1.154
13.997ArgArg: 13.997 ± 7.52
4.666ArgSer: 4.666 ± 3.241
6.221ArgThr: 6.221 ± 2.09
3.11ArgVal: 3.11 ± 2.692
0.0ArgTrp: 0.0 ± 0.0
6.221ArgTyr: 6.221 ± 1.356
0.0ArgXaa: 0.0 ± 0.0
Ser
3.11SerAla: 3.11 ± 2.692
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
3.11SerGlu: 3.11 ± 2.249
1.555SerPhe: 1.555 ± 1.154
4.666SerGly: 4.666 ± 1.331
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
6.221SerLys: 6.221 ± 3.04
1.555SerLeu: 1.555 ± 1.8
3.11SerMet: 3.11 ± 2.378
4.666SerAsn: 4.666 ± 2.091
7.776SerPro: 7.776 ± 3.465
3.11SerGln: 3.11 ± 2.249
1.555SerArg: 1.555 ± 1.8
9.331SerSer: 9.331 ± 5.763
4.666SerThr: 4.666 ± 1.331
4.666SerVal: 4.666 ± 1.792
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.11ThrAla: 3.11 ± 0.678
1.555ThrCys: 1.555 ± 1.346
4.666ThrAsp: 4.666 ± 4.039
4.666ThrGlu: 4.666 ± 3.178
0.0ThrPhe: 0.0 ± 0.0
3.11ThrGly: 3.11 ± 2.309
3.11ThrHis: 3.11 ± 0.678
7.776ThrIle: 7.776 ± 4.021
1.555ThrLys: 1.555 ± 1.154
4.666ThrLeu: 4.666 ± 1.268
1.555ThrMet: 1.555 ± 1.346
4.666ThrAsn: 4.666 ± 3.846
1.555ThrPro: 1.555 ± 1.346
4.666ThrGln: 4.666 ± 2.091
1.555ThrArg: 1.555 ± 1.154
1.555ThrSer: 1.555 ± 1.154
3.11ThrThr: 3.11 ± 3.6
4.666ThrVal: 4.666 ± 3.241
1.555ThrTrp: 1.555 ± 1.154
6.221ThrTyr: 6.221 ± 3.097
0.0ThrXaa: 0.0 ± 0.0
Val
9.331ValAla: 9.331 ± 5.763
0.0ValCys: 0.0 ± 0.0
3.11ValAsp: 3.11 ± 2.249
4.666ValGlu: 4.666 ± 1.268
3.11ValPhe: 3.11 ± 0.678
4.666ValGly: 4.666 ± 1.331
0.0ValHis: 0.0 ± 0.0
4.666ValIle: 4.666 ± 1.331
1.555ValLys: 1.555 ± 1.346
3.11ValLeu: 3.11 ± 1.573
1.555ValMet: 1.555 ± 1.322
1.555ValAsn: 1.555 ± 1.346
0.0ValPro: 0.0 ± 0.0
4.666ValGln: 4.666 ± 3.241
3.11ValArg: 3.11 ± 2.692
0.0ValSer: 0.0 ± 0.0
3.11ValThr: 3.11 ± 2.692
1.555ValVal: 1.555 ± 1.346
0.0ValTrp: 0.0 ± 0.0
1.555ValTyr: 1.555 ± 1.346
0.0ValXaa: 0.0 ± 0.0
Trp
3.11TrpAla: 3.11 ± 0.678
1.555TrpCys: 1.555 ± 1.346
1.555TrpAsp: 1.555 ± 1.154
0.0TrpGlu: 0.0 ± 0.0
1.555TrpPhe: 1.555 ± 1.346
0.0TrpGly: 0.0 ± 0.0
1.555TrpHis: 1.555 ± 1.8
0.0TrpIle: 0.0 ± 0.0
3.11TrpLys: 3.11 ± 1.573
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.555TrpArg: 1.555 ± 1.346
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.555TrpTyr: 1.555 ± 1.154
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.555TyrAla: 1.555 ± 1.346
3.11TyrCys: 3.11 ± 2.309
3.11TyrAsp: 3.11 ± 0.678
1.555TyrGlu: 1.555 ± 1.154
1.555TyrPhe: 1.555 ± 1.346
6.221TyrGly: 6.221 ± 4.617
1.555TyrHis: 1.555 ± 1.8
3.11TyrIle: 3.11 ± 2.309
1.555TyrLys: 1.555 ± 1.154
1.555TyrLeu: 1.555 ± 1.346
1.555TyrMet: 1.555 ± 1.154
3.11TyrAsn: 3.11 ± 2.309
3.11TyrPro: 3.11 ± 2.309
6.221TyrGln: 6.221 ± 3.097
6.221TyrArg: 6.221 ± 4.499
4.666TyrSer: 4.666 ± 3.241
3.11TyrThr: 3.11 ± 1.573
1.555TyrVal: 1.555 ± 1.346
1.555TyrTrp: 1.555 ± 1.154
4.666TyrTyr: 4.666 ± 3.846
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (644 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski