Amino acid dipepetide frequency for Panacibacter ginsenosidivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.85AlaAla: 6.85 ± 0.096	0.807AlaCys: 0.807 ± 0.028	4.453AlaAsp: 4.453 ± 0.064	3.985AlaGlu: 3.985 ± 0.059	3.655AlaPhe: 3.655 ± 0.049	5.648AlaGly: 5.648 ± 0.068	1.312AlaHis: 1.312 ± 0.032	5.606AlaIle: 5.606 ± 0.07	4.924AlaLys: 4.924 ± 0.065	6.818AlaLeu: 6.818 ± 0.07	1.919AlaMet: 1.919 ± 0.035	3.703AlaAsn: 3.703 ± 0.049	2.319AlaPro: 2.319 ± 0.044	2.739AlaGln: 2.739 ± 0.044	2.247AlaArg: 2.247 ± 0.037	4.425AlaSer: 4.425 ± 0.055	4.483AlaThr: 4.483 ± 0.065	5.164AlaVal: 5.164 ± 0.057	0.89AlaTrp: 0.89 ± 0.03	2.915AlaTyr: 2.915 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.651CysAla: 0.651 ± 0.023	0.179CysCys: 0.179 ± 0.011	0.503CysAsp: 0.503 ± 0.02	0.425CysGlu: 0.425 ± 0.018	0.521CysPhe: 0.521 ± 0.017	0.747CysGly: 0.747 ± 0.025	0.233CysHis: 0.233 ± 0.011	0.84CysIle: 0.84 ± 0.024	0.618CysLys: 0.618 ± 0.022	0.8CysLeu: 0.8 ± 0.028	0.256CysMet: 0.256 ± 0.014	0.589CysAsn: 0.589 ± 0.021	0.39CysPro: 0.39 ± 0.018	0.217CysGln: 0.217 ± 0.011	0.332CysArg: 0.332 ± 0.017	0.644CysSer: 0.644 ± 0.023	0.556CysThr: 0.556 ± 0.021	0.566CysVal: 0.566 ± 0.021	0.115CysTrp: 0.115 ± 0.008	0.416CysTyr: 0.416 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.576AspAla: 4.576 ± 0.057	0.458AspCys: 0.458 ± 0.02	2.774AspAsp: 2.774 ± 0.05	3.512AspGlu: 3.512 ± 0.05	3.02AspPhe: 3.02 ± 0.052	3.868AspGly: 3.868 ± 0.063	1.036AspHis: 1.036 ± 0.028	4.243AspIle: 4.243 ± 0.058	4.149AspLys: 4.149 ± 0.055	4.436AspLeu: 4.436 ± 0.055	1.251AspMet: 1.251 ± 0.031	2.997AspAsn: 2.997 ± 0.054	1.955AspPro: 1.955 ± 0.039	1.336AspGln: 1.336 ± 0.031	1.649AspArg: 1.649 ± 0.035	3.343AspSer: 3.343 ± 0.062	2.96AspThr: 2.96 ± 0.049	3.538AspVal: 3.538 ± 0.048	0.783AspTrp: 0.783 ± 0.025	2.62AspTyr: 2.62 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	3.969GluAla: 3.969 ± 0.058	0.394GluCys: 0.394 ± 0.018	2.815GluAsp: 2.815 ± 0.053	3.684GluGlu: 3.684 ± 0.075	2.212GluPhe: 2.212 ± 0.044	3.101GluGly: 3.101 ± 0.045	1.129GluHis: 1.129 ± 0.03	4.296GluIle: 4.296 ± 0.059	5.183GluLys: 5.183 ± 0.069	5.22GluLeu: 5.22 ± 0.069	1.62GluMet: 1.62 ± 0.037	3.373GluAsn: 3.373 ± 0.045	1.663GluPro: 1.663 ± 0.033	2.39GluGln: 2.39 ± 0.036	2.272GluArg: 2.272 ± 0.039	2.645GluSer: 2.645 ± 0.042	3.141GluThr: 3.141 ± 0.048	3.39GluVal: 3.39 ± 0.052	0.769GluTrp: 0.769 ± 0.025	2.037GluTyr: 2.037 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.648PheAla: 3.648 ± 0.05	0.569PheCys: 0.569 ± 0.022	2.883PheAsp: 2.883 ± 0.052	2.692PheGlu: 2.692 ± 0.048	2.81PhePhe: 2.81 ± 0.061	3.341PheGly: 3.341 ± 0.048	0.854PheHis: 0.854 ± 0.025	4.224PheIle: 4.224 ± 0.062	3.172PheLys: 3.172 ± 0.047	4.261PheLeu: 4.261 ± 0.058	1.109PheMet: 1.109 ± 0.028	2.91PheAsn: 2.91 ± 0.048	1.769PhePro: 1.769 ± 0.034	1.354PheGln: 1.354 ± 0.031	1.736PheArg: 1.736 ± 0.04	3.793PheSer: 3.793 ± 0.056	3.398PheThr: 3.398 ± 0.056	2.984PheVal: 2.984 ± 0.05	0.597PheTrp: 0.597 ± 0.021	2.176PheTyr: 2.176 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.503GlyAla: 4.503 ± 0.073	0.761GlyCys: 0.761 ± 0.027	3.436GlyAsp: 3.436 ± 0.062	3.203GlyGlu: 3.203 ± 0.049	3.526GlyPhe: 3.526 ± 0.044	4.815GlyGly: 4.815 ± 0.092	1.187GlyHis: 1.187 ± 0.031	5.403GlyIle: 5.403 ± 0.066	5.242GlyLys: 5.242 ± 0.059	5.685GlyLeu: 5.685 ± 0.074	1.72GlyMet: 1.72 ± 0.033	4.021GlyAsn: 4.021 ± 0.064	1.479GlyPro: 1.479 ± 0.031	1.792GlyGln: 1.792 ± 0.041	2.305GlyArg: 2.305 ± 0.041	4.239GlySer: 4.239 ± 0.067	4.224GlyThr: 4.224 ± 0.079	4.11GlyVal: 4.11 ± 0.054	1.013GlyTrp: 1.013 ± 0.027	3.164GlyTyr: 3.164 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.439HisAla: 1.439 ± 0.031	0.225HisCys: 0.225 ± 0.013	0.978HisAsp: 0.978 ± 0.023	1.082HisGlu: 1.082 ± 0.027	1.206HisPhe: 1.206 ± 0.03	1.232HisGly: 1.232 ± 0.027	0.553HisHis: 0.553 ± 0.024	1.539HisIle: 1.539 ± 0.033	1.146HisLys: 1.146 ± 0.024	1.797HisLeu: 1.797 ± 0.039	0.407HisMet: 0.407 ± 0.016	1.024HisAsn: 1.024 ± 0.021	1.002HisPro: 1.002 ± 0.031	0.624HisGln: 0.624 ± 0.019	0.692HisArg: 0.692 ± 0.023	1.075HisSer: 1.075 ± 0.03	1.096HisThr: 1.096 ± 0.03	1.132HisVal: 1.132 ± 0.028	0.304HisTrp: 0.304 ± 0.014	0.972HisTyr: 0.972 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.298IleAla: 6.298 ± 0.073	0.796IleCys: 0.796 ± 0.025	4.442IleAsp: 4.442 ± 0.065	4.346IleGlu: 4.346 ± 0.067	3.611IlePhe: 3.611 ± 0.057	4.749IleGly: 4.749 ± 0.054	1.45IleHis: 1.45 ± 0.033	6.179IleIle: 6.179 ± 0.073	5.416IleLys: 5.416 ± 0.066	6.436IleLeu: 6.436 ± 0.071	1.544IleMet: 1.544 ± 0.032	4.577IleAsn: 4.577 ± 0.065	3.168IlePro: 3.168 ± 0.048	2.43IleGln: 2.43 ± 0.044	2.686IleArg: 2.686 ± 0.045	5.181IleSer: 5.181 ± 0.063	4.973IleThr: 4.973 ± 0.068	4.684IleVal: 4.684 ± 0.056	0.724IleTrp: 0.724 ± 0.023	2.788IleTyr: 2.788 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	5.27LysAla: 5.27 ± 0.075	0.419LysCys: 0.419 ± 0.017	4.663LysAsp: 4.663 ± 0.063	5.494LysGlu: 5.494 ± 0.074	2.717LysPhe: 2.717 ± 0.042	4.406LysGly: 4.406 ± 0.06	1.343LysHis: 1.343 ± 0.028	5.586LysIle: 5.586 ± 0.073	6.149LysLys: 6.149 ± 0.079	6.037LysLeu: 6.037 ± 0.06	2.124LysMet: 2.124 ± 0.039	4.448LysAsn: 4.448 ± 0.06	2.752LysPro: 2.752 ± 0.045	3.172LysGln: 3.172 ± 0.052	2.734LysArg: 2.734 ± 0.039	3.695LysSer: 3.695 ± 0.05	4.246LysThr: 4.246 ± 0.048	4.179LysVal: 4.179 ± 0.058	0.925LysTrp: 0.925 ± 0.026	2.888LysTyr: 2.888 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	6.132LeuAla: 6.132 ± 0.067	0.93LeuCys: 0.93 ± 0.025	4.387LeuAsp: 4.387 ± 0.055	4.312LeuGlu: 4.312 ± 0.067	4.873LeuPhe: 4.873 ± 0.074	5.254LeuGly: 5.254 ± 0.061	2.002LeuHis: 2.002 ± 0.036	6.311LeuIle: 6.311 ± 0.077	6.65LeuLys: 6.65 ± 0.076	9.509LeuLeu: 9.509 ± 0.102	2.167LeuMet: 2.167 ± 0.042	5.136LeuAsn: 5.136 ± 0.066	3.907LeuPro: 3.907 ± 0.053	4.28LeuGln: 4.28 ± 0.056	3.356LeuArg: 3.356 ± 0.05	6.501LeuSer: 6.501 ± 0.072	5.122LeuThr: 5.122 ± 0.067	5.104LeuVal: 5.104 ± 0.057	0.963LeuTrp: 0.963 ± 0.027	3.433LeuTyr: 3.433 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	1.699MetAla: 1.699 ± 0.036	0.195MetCys: 0.195 ± 0.011	1.168MetAsp: 1.168 ± 0.029	1.382MetGlu: 1.382 ± 0.029	0.967MetPhe: 0.967 ± 0.024	1.51MetGly: 1.51 ± 0.038	0.655MetHis: 0.655 ± 0.021	1.664MetIle: 1.664 ± 0.035	2.175MetLys: 2.175 ± 0.04	2.395MetLeu: 2.395 ± 0.043	0.724MetMet: 0.724 ± 0.021	1.395MetAsn: 1.395 ± 0.032	1.187MetPro: 1.187 ± 0.031	1.471MetGln: 1.471 ± 0.033	0.997MetArg: 0.997 ± 0.024	1.391MetSer: 1.391 ± 0.03	1.09MetThr: 1.09 ± 0.03	1.351MetVal: 1.351 ± 0.029	0.214MetTrp: 0.214 ± 0.012	0.798MetTyr: 0.798 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	4.411AsnAla: 4.411 ± 0.061	0.535AsnCys: 0.535 ± 0.023	3.328AsnAsp: 3.328 ± 0.055	3.286AsnGlu: 3.286 ± 0.049	2.816AsnPhe: 2.816 ± 0.045	4.134AsnGly: 4.134 ± 0.07	0.943AsnHis: 0.943 ± 0.022	5.038AsnIle: 5.038 ± 0.059	4.23AsnLys: 4.23 ± 0.056	4.408AsnLeu: 4.408 ± 0.062	1.325AsnMet: 1.325 ± 0.027	4.117AsnAsn: 4.117 ± 0.073	2.548AsnPro: 2.548 ± 0.044	1.607AsnGln: 1.607 ± 0.034	1.982AsnArg: 1.982 ± 0.037	3.333AsnSer: 3.333 ± 0.051	3.624AsnThr: 3.624 ± 0.074	3.37AsnVal: 3.37 ± 0.06	0.761AsnTrp: 0.761 ± 0.021	2.723AsnTyr: 2.723 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	3.177ProAla: 3.177 ± 0.049	0.275ProCys: 0.275 ± 0.013	2.47ProAsp: 2.47 ± 0.039	2.466ProGlu: 2.466 ± 0.041	2.015ProPhe: 2.015 ± 0.035	2.653ProGly: 2.653 ± 0.051	0.766ProHis: 0.766 ± 0.022	2.037ProIle: 2.037 ± 0.033	2.082ProLys: 2.082 ± 0.039	3.277ProLeu: 3.277 ± 0.042	0.792ProMet: 0.792 ± 0.022	1.893ProAsn: 1.893 ± 0.034	1.122ProPro: 1.122 ± 0.031	1.353ProGln: 1.353 ± 0.033	0.984ProArg: 0.984 ± 0.026	2.207ProSer: 2.207 ± 0.044	1.86ProThr: 1.86 ± 0.041	3.428ProVal: 3.428 ± 0.049	0.446ProTrp: 0.446 ± 0.017	1.607ProTyr: 1.607 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.145GlnAla: 2.145 ± 0.04	0.274GlnCys: 0.274 ± 0.013	1.5GlnAsp: 1.5 ± 0.03	1.761GlnGlu: 1.761 ± 0.037	1.73GlnPhe: 1.73 ± 0.031	1.812GlnGly: 1.812 ± 0.034	0.914GlnHis: 0.914 ± 0.024	2.221GlnIle: 2.221 ± 0.034	2.839GlnLys: 2.839 ± 0.05	4.062GlnLeu: 4.062 ± 0.053	1.055GlnMet: 1.055 ± 0.024	2.02GlnAsn: 2.02 ± 0.039	1.497GlnPro: 1.497 ± 0.032	2.477GlnGln: 2.477 ± 0.049	1.493GlnArg: 1.493 ± 0.034	2.175GlnSer: 2.175 ± 0.04	2.161GlnThr: 2.161 ± 0.041	2.132GlnVal: 2.132 ± 0.041	0.494GlnTrp: 0.494 ± 0.02	1.611GlnTyr: 1.611 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.015ArgAla: 2.015 ± 0.043	0.28ArgCys: 0.28 ± 0.017	1.778ArgAsp: 1.778 ± 0.037	1.872ArgGlu: 1.872 ± 0.036	1.908ArgPhe: 1.908 ± 0.038	1.921ArgGly: 1.921 ± 0.04	0.666ArgHis: 0.666 ± 0.021	2.969ArgIle: 2.969 ± 0.049	2.966ArgLys: 2.966 ± 0.046	3.288ArgLeu: 3.288 ± 0.047	1.039ArgMet: 1.039 ± 0.024	2.3ArgAsn: 2.3 ± 0.044	1.187ArgPro: 1.187 ± 0.026	1.271ArgGln: 1.271 ± 0.028	1.438ArgArg: 1.438 ± 0.036	2.115ArgSer: 2.115 ± 0.035	1.874ArgThr: 1.874 ± 0.036	2.034ArgVal: 2.034 ± 0.04	0.474ArgTrp: 0.474 ± 0.02	1.634ArgTyr: 1.634 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	4.496SerAla: 4.496 ± 0.057	0.731SerCys: 0.731 ± 0.024	3.022SerAsp: 3.022 ± 0.043	2.76SerGlu: 2.76 ± 0.043	3.913SerPhe: 3.913 ± 0.055	4.632SerGly: 4.632 ± 0.074	1.015SerHis: 1.015 ± 0.027	4.9SerIle: 4.9 ± 0.057	4.135SerLys: 4.135 ± 0.051	6.104SerLeu: 6.104 ± 0.064	1.401SerMet: 1.401 ± 0.03	3.562SerAsn: 3.562 ± 0.059	2.1SerPro: 2.1 ± 0.04	1.768SerGln: 1.768 ± 0.038	2.013SerArg: 2.013 ± 0.04	4.107SerSer: 4.107 ± 0.068	3.709SerThr: 3.709 ± 0.064	4.249SerVal: 4.249 ± 0.061	0.771SerTrp: 0.771 ± 0.027	2.661SerTyr: 2.661 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	5.108ThrAla: 5.108 ± 0.07	0.473ThrCys: 0.473 ± 0.019	3.536ThrAsp: 3.536 ± 0.05	3.079ThrGlu: 3.079 ± 0.05	2.721ThrPhe: 2.721 ± 0.042	4.949ThrGly: 4.949 ± 0.074	1.062ThrHis: 1.062 ± 0.027	4.777ThrIle: 4.777 ± 0.074	3.663ThrLys: 3.663 ± 0.044	5.168ThrLeu: 5.168 ± 0.061	1.103ThrMet: 1.103 ± 0.026	3.216ThrAsn: 3.216 ± 0.058	2.415ThrPro: 2.415 ± 0.048	1.853ThrGln: 1.853 ± 0.036	1.726ThrArg: 1.726 ± 0.032	3.627ThrSer: 3.627 ± 0.068	3.989ThrThr: 3.989 ± 0.086	4.09ThrVal: 4.09 ± 0.069	0.755ThrTrp: 0.755 ± 0.026	2.375ThrTyr: 2.375 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	4.765ValAla: 4.765 ± 0.07	0.744ValCys: 0.744 ± 0.023	3.244ValAsp: 3.244 ± 0.045	3.21ValGlu: 3.21 ± 0.049	3.094ValPhe: 3.094 ± 0.042	3.523ValGly: 3.523 ± 0.05	1.206ValHis: 1.206 ± 0.023	4.924ValIle: 4.924 ± 0.059	4.492ValLys: 4.492 ± 0.061	5.695ValLeu: 5.695 ± 0.069	1.628ValMet: 1.628 ± 0.031	3.591ValAsn: 3.591 ± 0.055	2.412ValPro: 2.412 ± 0.036	2.219ValGln: 2.219 ± 0.036	2.13ValArg: 2.13 ± 0.038	4.175ValSer: 4.175 ± 0.053	3.951ValThr: 3.951 ± 0.071	4.1ValVal: 4.1 ± 0.06	0.759ValTrp: 0.759 ± 0.023	2.624ValTyr: 2.624 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.733TrpAla: 0.733 ± 0.024	0.132TrpCys: 0.132 ± 0.009	0.702TrpAsp: 0.702 ± 0.024	0.632TrpGlu: 0.632 ± 0.023	0.617TrpPhe: 0.617 ± 0.021	0.82TrpGly: 0.82 ± 0.025	0.304TrpHis: 0.304 ± 0.014	0.903TrpIle: 0.903 ± 0.023	0.95TrpLys: 0.95 ± 0.024	1.261TrpLeu: 1.261 ± 0.032	0.396TrpMet: 0.396 ± 0.018	0.835TrpAsn: 0.835 ± 0.024	0.348TrpPro: 0.348 ± 0.017	0.591TrpGln: 0.591 ± 0.02	0.514TrpArg: 0.514 ± 0.02	0.716TrpSer: 0.716 ± 0.024	0.605TrpThr: 0.605 ± 0.022	0.734TrpVal: 0.734 ± 0.023	0.251TrpTrp: 0.251 ± 0.013	0.523TrpTyr: 0.523 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.979TyrAla: 2.979 ± 0.045	0.425TyrCys: 0.425 ± 0.02	2.417TyrAsp: 2.417 ± 0.046	2.118TyrGlu: 2.118 ± 0.038	2.349TyrPhe: 2.349 ± 0.044	2.714TyrGly: 2.714 ± 0.05	0.897TyrHis: 0.897 ± 0.027	2.817TyrIle: 2.817 ± 0.043	3.065TyrLys: 3.065 ± 0.048	3.674TyrLeu: 3.674 ± 0.058	0.848TyrMet: 0.848 ± 0.025	2.81TyrAsn: 2.81 ± 0.049	1.689TyrPro: 1.689 ± 0.036	1.428TyrGln: 1.428 ± 0.034	1.741TyrArg: 1.741 ± 0.043	2.659TyrSer: 2.659 ± 0.042	2.622TyrThr: 2.622 ± 0.049	2.149TyrVal: 2.149 ± 0.04	0.564TyrTrp: 0.564 ± 0.022	2.033TyrTyr: 2.033 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4562 proteins (1552168 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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