Amino acid dipepetide frequency for Barbel circovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.759AlaAla: 3.759 ± 2.444
1.88AlaCys: 1.88 ± 1.222
7.519AlaAsp: 7.519 ± 4.247
3.759AlaGlu: 3.759 ± 2.444
0.0AlaPhe: 0.0 ± 0.0
5.639AlaGly: 5.639 ± 0.621
0.0AlaHis: 0.0 ± 0.0
7.519AlaIle: 7.519 ± 1.202
1.88AlaLys: 1.88 ± 1.222
0.0AlaLeu: 0.0 ± 0.0
1.88AlaMet: 1.88 ± 1.222
1.88AlaAsn: 1.88 ± 1.222
1.88AlaPro: 1.88 ± 1.823
1.88AlaGln: 1.88 ± 1.222
3.759AlaArg: 3.759 ± 0.601
5.639AlaSer: 5.639 ± 2.424
7.519AlaThr: 7.519 ± 1.202
7.519AlaVal: 7.519 ± 1.843
1.88AlaTrp: 1.88 ± 1.823
1.88AlaTyr: 1.88 ± 1.222
0.0AlaXaa: 0.0 ± 0.0
Cys
1.88CysAla: 1.88 ± 1.222
0.0CysCys: 0.0 ± 0.0
1.88CysAsp: 1.88 ± 1.222
0.0CysGlu: 0.0 ± 0.0
1.88CysPhe: 1.88 ± 1.222
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.88CysLys: 1.88 ± 1.222
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.88CysPro: 1.88 ± 1.222
0.0CysGln: 0.0 ± 0.0
1.88CysArg: 1.88 ± 1.222
1.88CysSer: 1.88 ± 1.222
1.88CysThr: 1.88 ± 1.222
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.88CysTyr: 1.88 ± 1.222
0.0CysXaa: 0.0 ± 0.0
Asp
1.88AspAla: 1.88 ± 1.823
0.0AspCys: 0.0 ± 0.0
3.759AspAsp: 3.759 ± 0.601
3.759AspGlu: 3.759 ± 2.444
5.639AspPhe: 5.639 ± 3.666
7.519AspGly: 7.519 ± 1.843
1.88AspHis: 1.88 ± 1.823
0.0AspIle: 0.0 ± 0.0
1.88AspLys: 1.88 ± 1.823
3.759AspLeu: 3.759 ± 2.444
1.88AspMet: 1.88 ± 1.823
1.88AspAsn: 1.88 ± 1.222
7.519AspPro: 7.519 ± 1.843
0.0AspGln: 0.0 ± 0.0
3.759AspArg: 3.759 ± 0.601
3.759AspSer: 3.759 ± 2.444
1.88AspThr: 1.88 ± 1.222
1.88AspVal: 1.88 ± 1.222
0.0AspTrp: 0.0 ± 0.0
7.519AspTyr: 7.519 ± 4.247
0.0AspXaa: 0.0 ± 0.0
Glu
3.759GluAla: 3.759 ± 2.444
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
1.88GluGlu: 1.88 ± 1.222
3.759GluPhe: 3.759 ± 0.601
1.88GluGly: 1.88 ± 1.222
0.0GluHis: 0.0 ± 0.0
3.759GluIle: 3.759 ± 0.601
0.0GluLys: 0.0 ± 0.0
3.759GluLeu: 3.759 ± 2.444
0.0GluMet: 0.0 ± 0.0
1.88GluAsn: 1.88 ± 1.222
1.88GluPro: 1.88 ± 1.222
1.88GluGln: 1.88 ± 1.222
5.639GluArg: 5.639 ± 3.666
1.88GluSer: 1.88 ± 1.222
0.0GluThr: 0.0 ± 0.0
1.88GluVal: 1.88 ± 1.222
0.0GluTrp: 0.0 ± 0.0
1.88GluTyr: 1.88 ± 1.222
0.0GluXaa: 0.0 ± 0.0
Phe
1.88PheAla: 1.88 ± 1.222
0.0PheCys: 0.0 ± 0.0
3.759PheAsp: 3.759 ± 2.444
1.88PheGlu: 1.88 ± 1.222
0.0PhePhe: 0.0 ± 0.0
0.0PheGly: 0.0 ± 0.0
0.0PheHis: 0.0 ± 0.0
3.759PheIle: 3.759 ± 0.601
3.759PheLys: 3.759 ± 0.601
5.639PheLeu: 5.639 ± 2.424
0.0PheMet: 0.0 ± 0.0
3.759PheAsn: 3.759 ± 0.601
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
3.759PheArg: 3.759 ± 3.646
0.0PheSer: 0.0 ± 0.0
3.759PheThr: 3.759 ± 0.601
3.759PheVal: 3.759 ± 2.444
0.0PheTrp: 0.0 ± 0.0
1.88PheTyr: 1.88 ± 1.222
0.0PheXaa: 0.0 ± 0.0
Gly
5.639GlyAla: 5.639 ± 2.424
1.88GlyCys: 1.88 ± 1.222
5.639GlyAsp: 5.639 ± 3.666
3.759GlyGlu: 3.759 ± 2.444
5.639GlyPhe: 5.639 ± 0.621
1.88GlyGly: 1.88 ± 1.222
0.0GlyHis: 0.0 ± 0.0
1.88GlyIle: 1.88 ± 1.823
1.88GlyLys: 1.88 ± 1.222
3.759GlyLeu: 3.759 ± 0.601
3.759GlyMet: 3.759 ± 0.601
1.88GlyAsn: 1.88 ± 1.222
1.88GlyPro: 1.88 ± 1.222
1.88GlyGln: 1.88 ± 1.222
5.639GlyArg: 5.639 ± 2.424
3.759GlySer: 3.759 ± 0.601
7.519GlyThr: 7.519 ± 4.888
1.88GlyVal: 1.88 ± 1.823
3.759GlyTrp: 3.759 ± 0.601
3.759GlyTyr: 3.759 ± 0.601
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
3.759HisAsp: 3.759 ± 3.646
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
3.759HisIle: 3.759 ± 0.601
0.0HisLys: 0.0 ± 0.0
5.639HisLeu: 5.639 ± 0.621
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.88HisArg: 1.88 ± 1.823
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.88HisVal: 1.88 ± 1.222
0.0HisTrp: 0.0 ± 0.0
1.88HisTyr: 1.88 ± 1.823
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
1.88IleAsp: 1.88 ± 1.222
1.88IleGlu: 1.88 ± 1.823
1.88IlePhe: 1.88 ± 1.823
7.519IleGly: 7.519 ± 1.843
0.0IleHis: 0.0 ± 0.0
3.759IleIle: 3.759 ± 0.601
3.759IleLys: 3.759 ± 3.646
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 1.086
3.759IleAsn: 3.759 ± 3.646
0.0IlePro: 0.0 ± 0.0
1.88IleGln: 1.88 ± 1.222
5.639IleArg: 5.639 ± 2.424
3.759IleSer: 3.759 ± 3.646
1.88IleThr: 1.88 ± 1.222
3.759IleVal: 3.759 ± 0.601
1.88IleTrp: 1.88 ± 1.823
3.759IleTyr: 3.759 ± 0.601
0.0IleXaa: 0.0 ± 0.0
Lys
5.639LysAla: 5.639 ± 3.666
0.0LysCys: 0.0 ± 0.0
1.88LysAsp: 1.88 ± 1.823
1.88LysGlu: 1.88 ± 1.222
1.88LysPhe: 1.88 ± 1.222
5.639LysGly: 5.639 ± 3.666
3.759LysHis: 3.759 ± 0.601
3.759LysIle: 3.759 ± 3.646
1.88LysLys: 1.88 ± 1.222
1.88LysLeu: 1.88 ± 1.823
1.88LysMet: 1.88 ± 1.823
1.88LysAsn: 1.88 ± 1.823
3.759LysPro: 3.759 ± 2.444
0.0LysGln: 0.0 ± 0.0
5.639LysArg: 5.639 ± 3.666
3.759LysSer: 3.759 ± 0.601
5.639LysThr: 5.639 ± 3.666
7.519LysVal: 7.519 ± 1.202
1.88LysTrp: 1.88 ± 1.222
3.759LysTyr: 3.759 ± 3.646
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.88LeuCys: 1.88 ± 1.222
0.0LeuAsp: 0.0 ± 0.0
0.0LeuGlu: 0.0 ± 0.0
1.88LeuPhe: 1.88 ± 1.823
1.88LeuGly: 1.88 ± 1.222
0.0LeuHis: 0.0 ± 0.0
1.88LeuIle: 1.88 ± 1.823
1.88LeuLys: 1.88 ± 1.823
3.759LeuLeu: 3.759 ± 0.601
1.88LeuMet: 1.88 ± 1.823
5.639LeuAsn: 5.639 ± 0.621
3.759LeuPro: 3.759 ± 3.646
7.519LeuGln: 7.519 ± 4.888
9.398LeuArg: 9.398 ± 3.065
0.0LeuSer: 0.0 ± 0.0
1.88LeuThr: 1.88 ± 1.823
1.88LeuVal: 1.88 ± 1.222
1.88LeuTrp: 1.88 ± 1.823
1.88LeuTyr: 1.88 ± 1.823
0.0LeuXaa: 0.0 ± 0.0
Met
3.759MetAla: 3.759 ± 3.646
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.88MetPhe: 1.88 ± 1.823
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
3.759MetLys: 3.759 ± 2.444
1.88MetLeu: 1.88 ± 1.823
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.759MetPro: 3.759 ± 2.444
1.88MetGln: 1.88 ± 1.222
5.639MetArg: 5.639 ± 3.666
3.759MetSer: 3.759 ± 3.646
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.88MetTrp: 1.88 ± 1.222
1.88MetTyr: 1.88 ± 1.222
0.0MetXaa: 0.0 ± 0.0
Asn
7.519AsnAla: 7.519 ± 1.202
0.0AsnCys: 0.0 ± 0.0
3.759AsnAsp: 3.759 ± 2.444
1.88AsnGlu: 1.88 ± 1.222
0.0AsnPhe: 0.0 ± 0.0
1.88AsnGly: 1.88 ± 1.823
0.0AsnHis: 0.0 ± 0.0
3.759AsnIle: 3.759 ± 3.646
1.88AsnLys: 1.88 ± 1.222
1.88AsnLeu: 1.88 ± 1.222
1.88AsnMet: 1.88 ± 1.222
3.759AsnAsn: 3.759 ± 0.601
3.759AsnPro: 3.759 ± 2.444
0.0AsnGln: 0.0 ± 0.0
3.759AsnArg: 3.759 ± 3.646
0.0AsnSer: 0.0 ± 0.0
3.759AsnThr: 3.759 ± 3.646
7.519AsnVal: 7.519 ± 1.843
0.0AsnTrp: 0.0 ± 0.0
3.759AsnTyr: 3.759 ± 3.646
0.0AsnXaa: 0.0 ± 0.0
Pro
3.759ProAla: 3.759 ± 2.444
3.759ProCys: 3.759 ± 2.444
0.0ProAsp: 0.0 ± 0.0
1.88ProGlu: 1.88 ± 1.823
1.88ProPhe: 1.88 ± 1.823
3.759ProGly: 3.759 ± 2.444
3.759ProHis: 3.759 ± 0.601
1.88ProIle: 1.88 ± 1.823
3.759ProLys: 3.759 ± 0.601
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
1.88ProAsn: 1.88 ± 1.823
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
11.278ProArg: 11.278 ± 1.242
3.759ProSer: 3.759 ± 3.646
1.88ProThr: 1.88 ± 1.222
5.639ProVal: 5.639 ± 3.666
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.88GlnAsp: 1.88 ± 1.222
1.88GlnGlu: 1.88 ± 1.222
0.0GlnPhe: 0.0 ± 0.0
1.88GlnGly: 1.88 ± 1.222
0.0GlnHis: 0.0 ± 0.0
1.88GlnIle: 1.88 ± 1.222
1.88GlnLys: 1.88 ± 1.222
1.88GlnLeu: 1.88 ± 1.823
0.0GlnMet: 0.0 ± 0.0
3.759GlnAsn: 3.759 ± 2.444
1.88GlnPro: 1.88 ± 1.222
1.88GlnGln: 1.88 ± 1.222
1.88GlnArg: 1.88 ± 1.823
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
0.0GlnVal: 0.0 ± 0.0
1.88GlnTrp: 1.88 ± 1.222
3.759GlnTyr: 3.759 ± 2.444
0.0GlnXaa: 0.0 ± 0.0
Arg
9.398ArgAla: 9.398 ± 3.025
1.88ArgCys: 1.88 ± 1.222
5.639ArgAsp: 5.639 ± 0.621
3.759ArgGlu: 3.759 ± 2.444
1.88ArgPhe: 1.88 ± 1.222
7.519ArgGly: 7.519 ± 1.202
5.639ArgHis: 5.639 ± 0.621
5.639ArgIle: 5.639 ± 2.424
7.519ArgLys: 7.519 ± 1.202
3.759ArgLeu: 3.759 ± 0.601
0.0ArgMet: 0.0 ± 0.0
3.759ArgAsn: 3.759 ± 0.601
1.88ArgPro: 1.88 ± 1.823
3.759ArgGln: 3.759 ± 0.601
26.316ArgArg: 26.316 ± 13.341
3.759ArgSer: 3.759 ± 0.601
3.759ArgThr: 3.759 ± 3.646
3.759ArgVal: 3.759 ± 2.444
1.88ArgTrp: 1.88 ± 1.222
7.519ArgTyr: 7.519 ± 1.843
0.0ArgXaa: 0.0 ± 0.0
Ser
5.639SerAla: 5.639 ± 2.424
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
1.88SerGlu: 1.88 ± 1.222
0.0SerPhe: 0.0 ± 0.0
7.519SerGly: 7.519 ± 1.202
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
5.639SerLys: 5.639 ± 0.621
0.0SerLeu: 0.0 ± 0.0
1.88SerMet: 1.88 ± 1.222
7.519SerAsn: 7.519 ± 4.247
0.0SerPro: 0.0 ± 0.0
0.0SerGln: 0.0 ± 0.0
3.759SerArg: 3.759 ± 0.601
7.519SerSer: 7.519 ± 4.247
7.519SerThr: 7.519 ± 4.247
1.88SerVal: 1.88 ± 1.222
0.0SerTrp: 0.0 ± 0.0
3.759SerTyr: 3.759 ± 3.646
0.0SerXaa: 0.0 ± 0.0
Thr
9.398ThrAla: 9.398 ± 0.02
0.0ThrCys: 0.0 ± 0.0
1.88ThrAsp: 1.88 ± 1.222
1.88ThrGlu: 1.88 ± 1.222
1.88ThrPhe: 1.88 ± 1.222
1.88ThrGly: 1.88 ± 1.823
1.88ThrHis: 1.88 ± 1.823
0.0ThrIle: 0.0 ± 0.0
3.759ThrLys: 3.759 ± 2.444
1.88ThrLeu: 1.88 ± 1.222
5.639ThrMet: 5.639 ± 0.621
1.88ThrAsn: 1.88 ± 1.823
3.759ThrPro: 3.759 ± 0.601
0.0ThrGln: 0.0 ± 0.0
3.759ThrArg: 3.759 ± 0.601
5.639ThrSer: 5.639 ± 0.621
1.88ThrThr: 1.88 ± 1.222
3.759ThrVal: 3.759 ± 0.601
1.88ThrTrp: 1.88 ± 1.823
1.88ThrTyr: 1.88 ± 1.222
0.0ThrXaa: 0.0 ± 0.0
Val
1.88ValAla: 1.88 ± 1.222
0.0ValCys: 0.0 ± 0.0
5.639ValAsp: 5.639 ± 0.621
1.88ValGlu: 1.88 ± 1.222
3.759ValPhe: 3.759 ± 0.601
1.88ValGly: 1.88 ± 1.222
1.88ValHis: 1.88 ± 1.823
3.759ValIle: 3.759 ± 2.444
7.519ValLys: 7.519 ± 4.888
3.759ValLeu: 3.759 ± 3.646
3.759ValMet: 3.759 ± 2.444
3.759ValAsn: 3.759 ± 2.444
5.639ValPro: 5.639 ± 2.424
1.88ValGln: 1.88 ± 1.823
1.88ValArg: 1.88 ± 1.823
1.88ValSer: 1.88 ± 1.222
3.759ValThr: 3.759 ± 2.444
5.639ValVal: 5.639 ± 2.424
1.88ValTrp: 1.88 ± 1.222
7.519ValTyr: 7.519 ± 4.888
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.88TrpCys: 1.88 ± 1.222
3.759TrpAsp: 3.759 ± 0.601
0.0TrpGlu: 0.0 ± 0.0
1.88TrpPhe: 1.88 ± 1.222
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.88TrpIle: 1.88 ± 1.823
0.0TrpLys: 0.0 ± 0.0
1.88TrpLeu: 1.88 ± 1.823
1.88TrpMet: 1.88 ± 1.222
1.88TrpAsn: 1.88 ± 1.823
1.88TrpPro: 1.88 ± 1.823
1.88TrpGln: 1.88 ± 1.222
1.88TrpArg: 1.88 ± 1.823
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.88TrpTrp: 1.88 ± 1.222
1.88TrpTyr: 1.88 ± 1.222
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.88TyrAla: 1.88 ± 1.222
3.759TyrCys: 3.759 ± 2.444
7.519TyrAsp: 7.519 ± 1.843
1.88TyrGlu: 1.88 ± 1.222
1.88TyrPhe: 1.88 ± 1.823
9.398TyrGly: 9.398 ± 3.025
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
9.398TyrLys: 9.398 ± 3.025
3.759TyrLeu: 3.759 ± 2.444
1.88TyrMet: 1.88 ± 0.852
0.0TyrAsn: 0.0 ± 0.0
3.759TyrPro: 3.759 ± 0.601
0.0TyrGln: 0.0 ± 0.0
1.88TyrArg: 1.88 ± 1.222
3.759TyrSer: 3.759 ± 3.646
0.0TyrThr: 0.0 ± 0.0
9.398TyrVal: 9.398 ± 0.02
1.88TyrTrp: 1.88 ± 1.823
5.639TyrTyr: 5.639 ± 2.424
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (533 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski