Amino acid dipepetide frequency for Gulbenkiania indica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.515AlaAla: 15.515 ± 0.218	1.384AlaCys: 1.384 ± 0.043	6.163AlaAsp: 6.163 ± 0.145	7.978AlaGlu: 7.978 ± 0.112	4.145AlaPhe: 4.145 ± 0.073	10.436AlaGly: 10.436 ± 0.132	2.578AlaHis: 2.578 ± 0.057	4.929AlaIle: 4.929 ± 0.085	3.071AlaLys: 3.071 ± 0.071	14.943AlaLeu: 14.943 ± 0.203	3.169AlaMet: 3.169 ± 0.063	2.821AlaAsn: 2.821 ± 0.068	5.506AlaPro: 5.506 ± 0.089	4.654AlaGln: 4.654 ± 0.088	9.692AlaArg: 9.692 ± 0.12	6.202AlaSer: 6.202 ± 0.09	5.534AlaThr: 5.534 ± 0.09	8.753AlaVal: 8.753 ± 0.103	1.807AlaTrp: 1.807 ± 0.051	2.668AlaTyr: 2.668 ± 0.055	0.001AlaXaa: 0.001 ± 0.001
Cys	0.962CysAla: 0.962 ± 0.039	0.128CysCys: 0.128 ± 0.014	0.522CysAsp: 0.522 ± 0.026	0.521CysGlu: 0.521 ± 0.026	0.297CysPhe: 0.297 ± 0.018	0.961CysGly: 0.961 ± 0.037	0.309CysHis: 0.309 ± 0.02	0.367CysIle: 0.367 ± 0.025	0.203CysLys: 0.203 ± 0.015	0.99CysLeu: 0.99 ± 0.044	0.185CysMet: 0.185 ± 0.014	0.268CysAsn: 0.268 ± 0.018	0.564CysPro: 0.564 ± 0.027	0.332CysGln: 0.332 ± 0.019	0.736CysArg: 0.736 ± 0.023	0.484CysSer: 0.484 ± 0.027	0.432CysThr: 0.432 ± 0.022	0.622CysVal: 0.622 ± 0.025	0.105CysTrp: 0.105 ± 0.01	0.264CysTyr: 0.264 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	6.286AspAla: 6.286 ± 0.141	0.45AspCys: 0.45 ± 0.024	2.663AspAsp: 2.663 ± 0.062	3.214AspGlu: 3.214 ± 0.065	2.002AspPhe: 2.002 ± 0.054	4.079AspGly: 4.079 ± 0.075	1.059AspHis: 1.059 ± 0.035	2.667AspIle: 2.667 ± 0.058	1.758AspLys: 1.758 ± 0.05	5.317AspLeu: 5.317 ± 0.087	1.23AspMet: 1.23 ± 0.041	1.269AspAsn: 1.269 ± 0.04	2.821AspPro: 2.821 ± 0.064	1.386AspGln: 1.386 ± 0.039	3.543AspArg: 3.543 ± 0.062	2.302AspSer: 2.302 ± 0.049	2.941AspThr: 2.941 ± 0.06	3.824AspVal: 3.824 ± 0.072	0.969AspTrp: 0.969 ± 0.035	1.538AspTyr: 1.538 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	8.733GluAla: 8.733 ± 0.127	0.44GluCys: 0.44 ± 0.024	2.72GluAsp: 2.72 ± 0.065	3.535GluGlu: 3.535 ± 0.077	1.671GluPhe: 1.671 ± 0.051	4.572GluGly: 4.572 ± 0.073	1.392GluHis: 1.392 ± 0.039	2.85GluIle: 2.85 ± 0.062	2.364GluLys: 2.364 ± 0.06	5.723GluLeu: 5.723 ± 0.099	1.498GluMet: 1.498 ± 0.039	1.583GluAsn: 1.583 ± 0.044	2.384GluPro: 2.384 ± 0.062	2.456GluGln: 2.456 ± 0.057	5.039GluArg: 5.039 ± 0.09	2.673GluSer: 2.673 ± 0.06	3.277GluThr: 3.277 ± 0.07	4.647GluVal: 4.647 ± 0.078	0.714GluTrp: 0.714 ± 0.032	1.261GluTyr: 1.261 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	4.126PheAla: 4.126 ± 0.075	0.409PheCys: 0.409 ± 0.022	2.359PheAsp: 2.359 ± 0.059	2.126PheGlu: 2.126 ± 0.053	1.432PhePhe: 1.432 ± 0.048	3.362PheGly: 3.362 ± 0.081	0.796PheHis: 0.796 ± 0.033	1.624PheIle: 1.624 ± 0.043	1.061PheLys: 1.061 ± 0.042	3.373PheLeu: 3.373 ± 0.078	0.844PheMet: 0.844 ± 0.036	1.218PheAsn: 1.218 ± 0.043	1.508PhePro: 1.508 ± 0.041	1.019PheGln: 1.019 ± 0.034	2.125PheArg: 2.125 ± 0.049	2.125PheSer: 2.125 ± 0.049	1.842PheThr: 1.842 ± 0.043	2.726PheVal: 2.726 ± 0.059	0.531PheTrp: 0.531 ± 0.029	1.012PheTyr: 1.012 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	7.61GlyAla: 7.61 ± 0.126	0.974GlyCys: 0.974 ± 0.04	3.633GlyAsp: 3.633 ± 0.074	4.844GlyGlu: 4.844 ± 0.067	3.353GlyPhe: 3.353 ± 0.061	6.15GlyGly: 6.15 ± 0.137	1.931GlyHis: 1.931 ± 0.049	3.841GlyIle: 3.841 ± 0.072	3.169GlyLys: 3.169 ± 0.069	9.556GlyLeu: 9.556 ± 0.133	2.282GlyMet: 2.282 ± 0.048	2.004GlyAsn: 2.004 ± 0.063	2.824GlyPro: 2.824 ± 0.058	3.408GlyGln: 3.408 ± 0.08	6.04GlyArg: 6.04 ± 0.082	4.272GlySer: 4.272 ± 0.097	4.022GlyThr: 4.022 ± 0.077	6.388GlyVal: 6.388 ± 0.094	1.463GlyTrp: 1.463 ± 0.049	2.352GlyTyr: 2.352 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	2.645HisAla: 2.645 ± 0.055	0.287HisCys: 0.287 ± 0.019	1.193HisAsp: 1.193 ± 0.04	1.195HisGlu: 1.195 ± 0.036	1.014HisPhe: 1.014 ± 0.036	1.998HisGly: 1.998 ± 0.046	0.672HisHis: 0.672 ± 0.031	0.923HisIle: 0.923 ± 0.031	0.552HisLys: 0.552 ± 0.026	2.501HisLeu: 2.501 ± 0.061	0.456HisMet: 0.456 ± 0.023	0.563HisAsn: 0.563 ± 0.028	1.653HisPro: 1.653 ± 0.049	0.799HisGln: 0.799 ± 0.032	1.489HisArg: 1.489 ± 0.047	0.987HisSer: 0.987 ± 0.034	1.163HisThr: 1.163 ± 0.037	1.469HisVal: 1.469 ± 0.041	0.4HisTrp: 0.4 ± 0.023	0.734HisTyr: 0.734 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.369IleAla: 5.369 ± 0.085	0.384IleCys: 0.384 ± 0.02	2.927IleAsp: 2.927 ± 0.053	3.085IleGlu: 3.085 ± 0.068	1.235IlePhe: 1.235 ± 0.046	4.087IleGly: 4.087 ± 0.075	0.959IleHis: 0.959 ± 0.032	1.709IleIle: 1.709 ± 0.054	1.47IleLys: 1.47 ± 0.048	3.845IleLeu: 3.845 ± 0.069	0.778IleMet: 0.778 ± 0.035	1.418IleAsn: 1.418 ± 0.046	1.983IlePro: 1.983 ± 0.051	1.263IleGln: 1.263 ± 0.041	3.23IleArg: 3.23 ± 0.056	2.236IleSer: 2.236 ± 0.056	2.435IleThr: 2.435 ± 0.053	3.528IleVal: 3.528 ± 0.07	0.401IleTrp: 0.401 ± 0.019	0.96IleTyr: 0.96 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	3.909LysAla: 3.909 ± 0.077	0.168LysCys: 0.168 ± 0.015	1.524LysAsp: 1.524 ± 0.053	1.666LysGlu: 1.666 ± 0.055	0.854LysPhe: 0.854 ± 0.038	2.466LysGly: 2.466 ± 0.06	0.664LysHis: 0.664 ± 0.025	1.452LysIle: 1.452 ± 0.056	1.539LysLys: 1.539 ± 0.062	3.482LysLeu: 3.482 ± 0.065	0.831LysMet: 0.831 ± 0.033	0.996LysAsn: 0.996 ± 0.038	1.904LysPro: 1.904 ± 0.051	1.261LysGln: 1.261 ± 0.042	2.204LysArg: 2.204 ± 0.049	1.598LysSer: 1.598 ± 0.046	1.912LysThr: 1.912 ± 0.053	2.583LysVal: 2.583 ± 0.057	0.339LysTrp: 0.339 ± 0.022	0.687LysTyr: 0.687 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	16.46LeuAla: 16.46 ± 0.195	1.03LeuCys: 1.03 ± 0.034	5.884LeuAsp: 5.884 ± 0.099	6.541LeuGlu: 6.541 ± 0.093	3.997LeuPhe: 3.997 ± 0.083	8.391LeuGly: 8.391 ± 0.111	2.18LeuHis: 2.18 ± 0.05	4.628LeuIle: 4.628 ± 0.084	4.0LeuLys: 4.0 ± 0.066	12.021LeuLeu: 12.021 ± 0.202	2.945LeuMet: 2.945 ± 0.067	2.896LeuAsn: 2.896 ± 0.068	6.945LeuPro: 6.945 ± 0.107	3.771LeuGln: 3.771 ± 0.074	7.248LeuArg: 7.248 ± 0.095	6.557LeuSer: 6.557 ± 0.115	6.366LeuThr: 6.366 ± 0.096	8.489LeuVal: 8.489 ± 0.13	1.371LeuTrp: 1.371 ± 0.047	2.534LeuTyr: 2.534 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	3.014MetAla: 3.014 ± 0.056	0.149MetCys: 0.149 ± 0.012	1.103MetAsp: 1.103 ± 0.037	1.223MetGlu: 1.223 ± 0.04	0.67MetPhe: 0.67 ± 0.034	1.847MetGly: 1.847 ± 0.051	0.609MetHis: 0.609 ± 0.026	1.012MetIle: 1.012 ± 0.036	1.118MetLys: 1.118 ± 0.038	2.829MetLeu: 2.829 ± 0.064	0.693MetMet: 0.693 ± 0.029	0.816MetAsn: 0.816 ± 0.026	1.371MetPro: 1.371 ± 0.043	1.166MetGln: 1.166 ± 0.035	1.656MetArg: 1.656 ± 0.052	1.43MetSer: 1.43 ± 0.041	1.51MetThr: 1.51 ± 0.038	1.819MetVal: 1.819 ± 0.045	0.227MetTrp: 0.227 ± 0.018	0.407MetTyr: 0.407 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.027AsnAla: 3.027 ± 0.069	0.227AsnCys: 0.227 ± 0.015	1.312AsnAsp: 1.312 ± 0.037	1.306AsnGlu: 1.306 ± 0.047	0.875AsnPhe: 0.875 ± 0.034	2.229AsnGly: 2.229 ± 0.055	0.576AsnHis: 0.576 ± 0.026	1.25AsnIle: 1.25 ± 0.035	0.802AsnLys: 0.802 ± 0.034	2.908AsnLeu: 2.908 ± 0.056	0.577AsnMet: 0.577 ± 0.028	0.774AsnAsn: 0.774 ± 0.037	1.926AsnPro: 1.926 ± 0.047	0.897AsnGln: 0.897 ± 0.036	2.04AsnArg: 2.04 ± 0.047	1.102AsnSer: 1.102 ± 0.041	1.426AsnThr: 1.426 ± 0.039	1.885AsnVal: 1.885 ± 0.055	0.368AsnTrp: 0.368 ± 0.022	0.685AsnTyr: 0.685 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.99ProAla: 6.99 ± 0.117	0.403ProCys: 0.403 ± 0.02	3.327ProAsp: 3.327 ± 0.067	3.789ProGlu: 3.789 ± 0.07	1.969ProPhe: 1.969 ± 0.048	4.176ProGly: 4.176 ± 0.072	1.131ProHis: 1.131 ± 0.034	1.756ProIle: 1.756 ± 0.059	1.427ProLys: 1.427 ± 0.049	5.653ProLeu: 5.653 ± 0.099	1.263ProMet: 1.263 ± 0.044	1.209ProAsn: 1.209 ± 0.041	2.542ProPro: 2.542 ± 0.067	1.945ProGln: 1.945 ± 0.051	2.779ProArg: 2.779 ± 0.071	2.534ProSer: 2.534 ± 0.061	2.324ProThr: 2.324 ± 0.05	4.799ProVal: 4.799 ± 0.092	0.712ProTrp: 0.712 ± 0.03	1.287ProTyr: 1.287 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	5.267GlnAla: 5.267 ± 0.097	0.246GlnCys: 0.246 ± 0.017	1.492GlnAsp: 1.492 ± 0.04	1.826GlnGlu: 1.826 ± 0.047	1.129GlnPhe: 1.129 ± 0.033	3.108GlnGly: 3.108 ± 0.081	0.917GlnHis: 0.917 ± 0.036	1.658GlnIle: 1.658 ± 0.051	1.333GlnLys: 1.333 ± 0.047	4.038GlnLeu: 4.038 ± 0.089	0.974GlnMet: 0.974 ± 0.038	0.878GlnAsn: 0.878 ± 0.033	2.356GlnPro: 2.356 ± 0.054	1.866GlnGln: 1.866 ± 0.061	2.863GlnArg: 2.863 ± 0.055	1.77GlnSer: 1.77 ± 0.047	1.954GlnThr: 1.954 ± 0.047	2.846GlnVal: 2.846 ± 0.06	0.5GlnTrp: 0.5 ± 0.025	0.81GlnTyr: 0.81 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	7.229ArgAla: 7.229 ± 0.107	0.532ArgCys: 0.532 ± 0.03	3.526ArgAsp: 3.526 ± 0.079	4.595ArgGlu: 4.595 ± 0.08	3.022ArgPhe: 3.022 ± 0.059	4.112ArgGly: 4.112 ± 0.077	2.072ArgHis: 2.072 ± 0.056	3.572ArgIle: 3.572 ± 0.07	2.146ArgLys: 2.146 ± 0.051	9.727ArgLeu: 9.727 ± 0.137	1.911ArgMet: 1.911 ± 0.052	1.892ArgAsn: 1.892 ± 0.054	3.703ArgPro: 3.703 ± 0.076	3.556ArgGln: 3.556 ± 0.061	5.354ArgArg: 5.354 ± 0.1	3.195ArgSer: 3.195 ± 0.064	3.447ArgThr: 3.447 ± 0.059	5.075ArgVal: 5.075 ± 0.076	1.106ArgTrp: 1.106 ± 0.042	2.178ArgTyr: 2.178 ± 0.053	0.0ArgXaa: 0.0 ± 0.0
Ser	6.013SerAla: 6.013 ± 0.085	0.415SerCys: 0.415 ± 0.023	2.425SerAsp: 2.425 ± 0.058	2.748SerGlu: 2.748 ± 0.062	1.858SerPhe: 1.858 ± 0.044	5.013SerGly: 5.013 ± 0.093	1.194SerHis: 1.194 ± 0.034	2.117SerIle: 2.117 ± 0.051	1.339SerLys: 1.339 ± 0.049	5.931SerLeu: 5.931 ± 0.084	1.266SerMet: 1.266 ± 0.037	1.234SerAsn: 1.234 ± 0.04	2.624SerPro: 2.624 ± 0.061	1.908SerGln: 1.908 ± 0.058	3.77SerArg: 3.77 ± 0.075	2.609SerSer: 2.609 ± 0.068	2.543SerThr: 2.543 ± 0.065	3.783SerVal: 3.783 ± 0.067	0.612SerTrp: 0.612 ± 0.027	1.237SerTyr: 1.237 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.728ThrAla: 5.728 ± 0.091	0.438ThrCys: 0.438 ± 0.023	2.59ThrAsp: 2.59 ± 0.051	2.673ThrGlu: 2.673 ± 0.052	1.806ThrPhe: 1.806 ± 0.048	4.756ThrGly: 4.756 ± 0.092	1.178ThrHis: 1.178 ± 0.036	2.004ThrIle: 2.004 ± 0.048	1.021ThrLys: 1.021 ± 0.039	7.461ThrLeu: 7.461 ± 0.108	0.979ThrMet: 0.979 ± 0.034	1.1ThrAsn: 1.1 ± 0.037	3.423ThrPro: 3.423 ± 0.063	1.753ThrGln: 1.753 ± 0.049	3.533ThrArg: 3.533 ± 0.072	2.39ThrSer: 2.39 ± 0.063	2.51ThrThr: 2.51 ± 0.06	4.621ThrVal: 4.621 ± 0.075	0.59ThrTrp: 0.59 ± 0.026	1.029ThrTyr: 1.029 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.248ValAla: 9.248 ± 0.117	0.776ValCys: 0.776 ± 0.029	4.114ValAsp: 4.114 ± 0.076	4.955ValGlu: 4.955 ± 0.081	2.785ValPhe: 2.785 ± 0.064	5.469ValGly: 5.469 ± 0.087	1.515ValHis: 1.515 ± 0.044	3.535ValIle: 3.535 ± 0.069	2.528ValLys: 2.528 ± 0.07	8.648ValLeu: 8.648 ± 0.114	1.907ValMet: 1.907 ± 0.051	2.172ValAsn: 2.172 ± 0.055	3.925ValPro: 3.925 ± 0.079	2.357ValGln: 2.357 ± 0.062	5.379ValArg: 5.379 ± 0.077	4.367ValSer: 4.367 ± 0.076	4.017ValThr: 4.017 ± 0.073	6.39ValVal: 6.39 ± 0.11	1.04ValTrp: 1.04 ± 0.04	1.688ValTyr: 1.688 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.251TrpAla: 1.251 ± 0.04	0.15TrpCys: 0.15 ± 0.012	0.497TrpAsp: 0.497 ± 0.022	0.543TrpGlu: 0.543 ± 0.028	0.494TrpPhe: 0.494 ± 0.024	0.847TrpGly: 0.847 ± 0.034	0.381TrpHis: 0.381 ± 0.021	0.518TrpIle: 0.518 ± 0.024	0.46TrpLys: 0.46 ± 0.026	2.406TrpLeu: 2.406 ± 0.067	0.411TrpMet: 0.411 ± 0.024	0.368TrpAsn: 0.368 ± 0.024	0.718TrpPro: 0.718 ± 0.033	0.991TrpGln: 0.991 ± 0.036	1.078TrpArg: 1.078 ± 0.042	0.615TrpSer: 0.615 ± 0.027	0.557TrpThr: 0.557 ± 0.023	1.004TrpVal: 1.004 ± 0.036	0.249TrpTrp: 0.249 ± 0.019	0.317TrpTyr: 0.317 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.569TyrAla: 2.569 ± 0.05	0.262TyrCys: 0.262 ± 0.018	1.343TyrAsp: 1.343 ± 0.044	1.169TyrGlu: 1.169 ± 0.038	1.011TyrPhe: 1.011 ± 0.038	2.059TyrGly: 2.059 ± 0.053	0.58TyrHis: 0.58 ± 0.029	0.889TyrIle: 0.889 ± 0.03	0.678TyrLys: 0.678 ± 0.033	2.9TyrLeu: 2.9 ± 0.059	0.468TyrMet: 0.468 ± 0.021	0.713TyrAsn: 0.713 ± 0.03	1.338TyrPro: 1.338 ± 0.041	1.04TyrGln: 1.04 ± 0.034	2.151TyrArg: 2.151 ± 0.056	1.194TyrSer: 1.194 ± 0.037	1.368TyrThr: 1.368 ± 0.04	1.564TyrVal: 1.564 ± 0.042	0.353TyrTrp: 0.353 ± 0.023	0.708TyrTyr: 0.708 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.014XaaXaa: 0.014 ± 0.016

Statistics based on 2697 proteins (858314 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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