Amino acid dipepetide frequency for Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) (Candida mogii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.707AlaAla: 4.707 ± 0.077
0.697AlaCys: 0.697 ± 0.018
2.82AlaAsp: 2.82 ± 0.034
3.389AlaGlu: 3.389 ± 0.045
2.381AlaPhe: 2.381 ± 0.039
3.435AlaGly: 3.435 ± 0.062
1.233AlaHis: 1.233 ± 0.023
3.395AlaIle: 3.395 ± 0.043
3.87AlaLys: 3.87 ± 0.048
5.583AlaLeu: 5.583 ± 0.061
1.286AlaMet: 1.286 ± 0.023
2.894AlaAsn: 2.894 ± 0.036
2.935AlaPro: 2.935 ± 0.069
2.636AlaGln: 2.636 ± 0.047
2.722AlaArg: 2.722 ± 0.034
5.13AlaSer: 5.13 ± 0.089
3.529AlaThr: 3.529 ± 0.049
3.58AlaVal: 3.58 ± 0.044
0.505AlaTrp: 0.505 ± 0.014
1.661AlaTyr: 1.661 ± 0.03
0.0AlaXaa: 0.0 ± 0.0
Cys
0.631CysAla: 0.631 ± 0.018
0.26CysCys: 0.26 ± 0.011
0.652CysAsp: 0.652 ± 0.016
0.635CysGlu: 0.635 ± 0.018
0.642CysPhe: 0.642 ± 0.019
0.853CysGly: 0.853 ± 0.022
0.327CysHis: 0.327 ± 0.014
0.868CysIle: 0.868 ± 0.022
0.724CysLys: 0.724 ± 0.02
1.245CysLeu: 1.245 ± 0.023
0.28CysMet: 0.28 ± 0.011
0.592CysAsn: 0.592 ± 0.015
0.526CysPro: 0.526 ± 0.02
0.509CysGln: 0.509 ± 0.015
0.556CysArg: 0.556 ± 0.016
0.981CysSer: 0.981 ± 0.02
0.562CysThr: 0.562 ± 0.017
0.831CysVal: 0.831 ± 0.019
0.166CysTrp: 0.166 ± 0.009
0.507CysTyr: 0.507 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
3.217AspAla: 3.217 ± 0.045
0.661AspCys: 0.661 ± 0.018
4.517AspAsp: 4.517 ± 0.074
5.398AspGlu: 5.398 ± 0.066
2.644AspPhe: 2.644 ± 0.039
3.236AspGly: 3.236 ± 0.044
1.198AspHis: 1.198 ± 0.019
3.496AspIle: 3.496 ± 0.041
3.476AspLys: 3.476 ± 0.039
5.528AspLeu: 5.528 ± 0.053
1.18AspMet: 1.18 ± 0.022
2.899AspAsn: 2.899 ± 0.041
2.732AspPro: 2.732 ± 0.035
2.271AspGln: 2.271 ± 0.034
2.376AspArg: 2.376 ± 0.032
4.848AspSer: 4.848 ± 0.053
2.892AspThr: 2.892 ± 0.031
3.79AspVal: 3.79 ± 0.043
0.697AspTrp: 0.697 ± 0.017
2.143AspTyr: 2.143 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
3.652GluAla: 3.652 ± 0.044
0.637GluCys: 0.637 ± 0.017
4.753GluAsp: 4.753 ± 0.066
6.545GluGlu: 6.545 ± 0.104
2.853GluPhe: 2.853 ± 0.039
3.161GluGly: 3.161 ± 0.04
1.34GluHis: 1.34 ± 0.027
3.883GluIle: 3.883 ± 0.04
4.988GluLys: 4.988 ± 0.073
6.896GluLeu: 6.896 ± 0.068
1.495GluMet: 1.495 ± 0.025
3.963GluAsn: 3.963 ± 0.044
2.552GluPro: 2.552 ± 0.041
3.079GluGln: 3.079 ± 0.047
3.255GluArg: 3.255 ± 0.044
5.231GluSer: 5.231 ± 0.064
3.452GluThr: 3.452 ± 0.047
3.64GluVal: 3.64 ± 0.042
0.65GluTrp: 0.65 ± 0.018
2.17GluTyr: 2.17 ± 0.032
0.0GluXaa: 0.0 ± 0.0
Phe
2.589PheAla: 2.589 ± 0.034
0.559PheCys: 0.559 ± 0.019
2.675PheAsp: 2.675 ± 0.035
2.9PheGlu: 2.9 ± 0.036
2.043PhePhe: 2.043 ± 0.037
2.74PheGly: 2.74 ± 0.048
1.029PheHis: 1.029 ± 0.02
2.483PheIle: 2.483 ± 0.035
2.796PheLys: 2.796 ± 0.041
4.106PheLeu: 4.106 ± 0.048
0.878PheMet: 0.878 ± 0.019
2.317PheAsn: 2.317 ± 0.03
1.813PhePro: 1.813 ± 0.03
2.047PheGln: 2.047 ± 0.034
1.719PheArg: 1.719 ± 0.026
3.364PheSer: 3.364 ± 0.043
2.366PheThr: 2.366 ± 0.033
2.696PheVal: 2.696 ± 0.034
0.525PheTrp: 0.525 ± 0.016
1.627PheTyr: 1.627 ± 0.029
0.0PheXaa: 0.0 ± 0.0
Gly
3.448GlyAla: 3.448 ± 0.082
0.74GlyCys: 0.74 ± 0.017
3.128GlyAsp: 3.128 ± 0.042
3.362GlyGlu: 3.362 ± 0.039
2.599GlyPhe: 2.599 ± 0.041
4.262GlyGly: 4.262 ± 0.078
1.233GlyHis: 1.233 ± 0.026
3.483GlyIle: 3.483 ± 0.043
3.89GlyLys: 3.89 ± 0.048
4.962GlyLeu: 4.962 ± 0.052
1.082GlyMet: 1.082 ± 0.022
3.108GlyAsn: 3.108 ± 0.055
2.078GlyPro: 2.078 ± 0.034
1.994GlyGln: 1.994 ± 0.032
2.451GlyArg: 2.451 ± 0.037
5.544GlySer: 5.544 ± 0.083
3.207GlyThr: 3.207 ± 0.044
3.521GlyVal: 3.521 ± 0.039
0.629GlyTrp: 0.629 ± 0.016
1.983GlyTyr: 1.983 ± 0.038
0.0GlyXaa: 0.0 ± 0.0
His
1.172HisAla: 1.172 ± 0.022
0.338HisCys: 0.338 ± 0.011
1.213HisAsp: 1.213 ± 0.021
1.38HisGlu: 1.38 ± 0.026
1.014HisPhe: 1.014 ± 0.021
1.36HisGly: 1.36 ± 0.028
0.768HisHis: 0.768 ± 0.023
1.237HisIle: 1.237 ± 0.027
1.287HisLys: 1.287 ± 0.024
2.259HisLeu: 2.259 ± 0.033
0.489HisMet: 0.489 ± 0.013
1.097HisAsn: 1.097 ± 0.021
1.128HisPro: 1.128 ± 0.02
0.996HisGln: 0.996 ± 0.023
1.232HisArg: 1.232 ± 0.026
1.825HisSer: 1.825 ± 0.03
1.104HisThr: 1.104 ± 0.023
1.28HisVal: 1.28 ± 0.027
0.307HisTrp: 0.307 ± 0.011
0.852HisTyr: 0.852 ± 0.017
0.0HisXaa: 0.0 ± 0.0
Ile
3.339IleAla: 3.339 ± 0.036
0.837IleCys: 0.837 ± 0.019
3.54IleAsp: 3.54 ± 0.041
3.354IleGlu: 3.354 ± 0.042
2.562IlePhe: 2.562 ± 0.043
3.014IleGly: 3.014 ± 0.045
1.265IleHis: 1.265 ± 0.024
3.06IleIle: 3.06 ± 0.038
3.564IleLys: 3.564 ± 0.044
5.566IleLeu: 5.566 ± 0.061
1.199IleMet: 1.199 ± 0.025
2.916IleAsn: 2.916 ± 0.037
3.056IlePro: 3.056 ± 0.037
2.164IleGln: 2.164 ± 0.033
2.749IleArg: 2.749 ± 0.032
4.933IleSer: 4.933 ± 0.049
3.06IleThr: 3.06 ± 0.04
3.494IleVal: 3.494 ± 0.04
0.714IleTrp: 0.714 ± 0.02
1.891IleTyr: 1.891 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
3.3LysAla: 3.3 ± 0.043
0.768LysCys: 0.768 ± 0.02
4.006LysAsp: 4.006 ± 0.051
4.898LysGlu: 4.898 ± 0.067
2.925LysPhe: 2.925 ± 0.037
3.047LysGly: 3.047 ± 0.036
1.385LysHis: 1.385 ± 0.027
3.8LysIle: 3.8 ± 0.039
5.492LysLys: 5.492 ± 0.072
6.702LysLeu: 6.702 ± 0.065
1.422LysMet: 1.422 ± 0.023
3.719LysAsn: 3.719 ± 0.043
3.063LysPro: 3.063 ± 0.05
2.71LysGln: 2.71 ± 0.036
3.945LysArg: 3.945 ± 0.052
5.226LysSer: 5.226 ± 0.055
3.38LysThr: 3.38 ± 0.04
3.83LysVal: 3.83 ± 0.041
0.774LysTrp: 0.774 ± 0.02
2.358LysTyr: 2.358 ± 0.033
0.0LysXaa: 0.0 ± 0.0
Leu
5.7LeuAla: 5.7 ± 0.051
1.332LeuCys: 1.332 ± 0.028
5.607LeuAsp: 5.607 ± 0.048
6.659LeuGlu: 6.659 ± 0.073
3.993LeuPhe: 3.993 ± 0.052
4.973LeuGly: 4.973 ± 0.051
2.155LeuHis: 2.155 ± 0.032
5.065LeuIle: 5.065 ± 0.062
6.93LeuLys: 6.93 ± 0.06
9.444LeuLeu: 9.444 ± 0.094
1.976LeuMet: 1.976 ± 0.032
5.069LeuAsn: 5.069 ± 0.044
4.83LeuPro: 4.83 ± 0.047
5.009LeuGln: 5.009 ± 0.047
4.86LeuArg: 4.86 ± 0.05
7.872LeuSer: 7.872 ± 0.062
4.994LeuThr: 4.994 ± 0.05
5.692LeuVal: 5.692 ± 0.061
1.0LeuTrp: 1.0 ± 0.021
3.005LeuTyr: 3.005 ± 0.039
0.0LeuXaa: 0.0 ± 0.0
Met
1.44MetAla: 1.44 ± 0.025
0.262MetCys: 0.262 ± 0.01
1.431MetAsp: 1.431 ± 0.027
1.379MetGlu: 1.379 ± 0.024
0.876MetPhe: 0.876 ± 0.021
1.343MetGly: 1.343 ± 0.027
0.397MetHis: 0.397 ± 0.013
1.152MetIle: 1.152 ± 0.024
1.292MetLys: 1.292 ± 0.021
1.875MetLeu: 1.875 ± 0.029
0.519MetMet: 0.519 ± 0.017
1.112MetAsn: 1.112 ± 0.019
0.875MetPro: 0.875 ± 0.024
0.767MetGln: 0.767 ± 0.022
0.957MetArg: 0.957 ± 0.02
1.967MetSer: 1.967 ± 0.029
1.081MetThr: 1.081 ± 0.024
1.401MetVal: 1.401 ± 0.024
0.197MetTrp: 0.197 ± 0.011
0.583MetTyr: 0.583 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
3.073AsnAla: 3.073 ± 0.033
0.634AsnCys: 0.634 ± 0.016
3.393AsnAsp: 3.393 ± 0.046
3.6AsnGlu: 3.6 ± 0.038
2.363AsnPhe: 2.363 ± 0.03
3.63AsnGly: 3.63 ± 0.067
1.182AsnHis: 1.182 ± 0.022
2.842AsnIle: 2.842 ± 0.038
3.349AsnLys: 3.349 ± 0.044
4.758AsnLeu: 4.758 ± 0.047
1.069AsnMet: 1.069 ± 0.023
3.561AsnAsn: 3.561 ± 0.07
2.459AsnPro: 2.459 ± 0.031
2.03AsnGln: 2.03 ± 0.032
2.332AsnArg: 2.332 ± 0.029
4.814AsnSer: 4.814 ± 0.061
2.791AsnThr: 2.791 ± 0.038
3.296AsnVal: 3.296 ± 0.038
0.647AsnTrp: 0.647 ± 0.015
1.861AsnTyr: 1.861 ± 0.03
0.0AsnXaa: 0.0 ± 0.0
Pro
2.743ProAla: 2.743 ± 0.052
0.378ProCys: 0.378 ± 0.013
2.279ProAsp: 2.279 ± 0.03
3.282ProGlu: 3.282 ± 0.041
1.904ProPhe: 1.904 ± 0.037
2.379ProGly: 2.379 ± 0.042
1.098ProHis: 1.098 ± 0.022
2.594ProIle: 2.594 ± 0.034
2.863ProLys: 2.863 ± 0.048
4.502ProLeu: 4.502 ± 0.055
0.883ProMet: 0.883 ± 0.022
2.337ProAsn: 2.337 ± 0.034
3.061ProPro: 3.061 ± 0.074
2.538ProGln: 2.538 ± 0.053
2.138ProArg: 2.138 ± 0.034
4.599ProSer: 4.599 ± 0.081
2.879ProThr: 2.879 ± 0.047
2.904ProVal: 2.904 ± 0.041
0.48ProTrp: 0.48 ± 0.015
1.384ProTyr: 1.384 ± 0.026
0.0ProXaa: 0.0 ± 0.0
Gln
2.341GlnAla: 2.341 ± 0.051
0.476GlnCys: 0.476 ± 0.014
2.571GlnAsp: 2.571 ± 0.034
3.566GlnGlu: 3.566 ± 0.051
1.88GlnPhe: 1.88 ± 0.026
2.202GlnGly: 2.202 ± 0.034
1.017GlnHis: 1.017 ± 0.024
2.307GlnIle: 2.307 ± 0.03
2.606GlnLys: 2.606 ± 0.035
4.844GlnLeu: 4.844 ± 0.049
0.942GlnMet: 0.942 ± 0.021
2.261GlnAsn: 2.261 ± 0.035
2.03GlnPro: 2.03 ± 0.052
3.704GlnGln: 3.704 ± 0.123
2.576GlnArg: 2.576 ± 0.032
3.164GlnSer: 3.164 ± 0.044
1.97GlnThr: 1.97 ± 0.03
2.558GlnVal: 2.558 ± 0.037
0.509GlnTrp: 0.509 ± 0.014
1.357GlnTyr: 1.357 ± 0.022
0.0GlnXaa: 0.0 ± 0.0
Arg
2.653ArgAla: 2.653 ± 0.033
0.661ArgCys: 0.661 ± 0.018
2.806ArgAsp: 2.806 ± 0.037
3.256ArgGlu: 3.256 ± 0.043
2.09ArgPhe: 2.09 ± 0.032
2.529ArgGly: 2.529 ± 0.037
1.164ArgHis: 1.164 ± 0.022
2.992ArgIle: 2.992 ± 0.036
3.569ArgLys: 3.569 ± 0.043
4.557ArgLeu: 4.557 ± 0.042
0.966ArgMet: 0.966 ± 0.021
2.628ArgAsn: 2.628 ± 0.032
2.034ArgPro: 2.034 ± 0.034
2.192ArgGln: 2.192 ± 0.031
3.366ArgArg: 3.366 ± 0.043
3.957ArgSer: 3.957 ± 0.047
2.45ArgThr: 2.45 ± 0.032
2.671ArgVal: 2.671 ± 0.031
0.541ArgTrp: 0.541 ± 0.017
1.652ArgTyr: 1.652 ± 0.028
0.0ArgXaa: 0.0 ± 0.0
Ser
4.797SerAla: 4.797 ± 0.076
0.927SerCys: 0.927 ± 0.023
4.393SerAsp: 4.393 ± 0.049
4.73SerGlu: 4.73 ± 0.056
3.488SerPhe: 3.488 ± 0.042
5.175SerGly: 5.175 ± 0.117
1.955SerHis: 1.955 ± 0.036
4.8SerIle: 4.8 ± 0.053
5.759SerLys: 5.759 ± 0.056
8.272SerLeu: 8.272 ± 0.06
1.894SerMet: 1.894 ± 0.029
4.927SerAsn: 4.927 ± 0.059
4.118SerPro: 4.118 ± 0.059
3.926SerGln: 3.926 ± 0.047
4.071SerArg: 4.071 ± 0.047
10.042SerSer: 10.042 ± 0.232
5.355SerThr: 5.355 ± 0.103
4.862SerVal: 4.862 ± 0.048
0.911SerTrp: 0.911 ± 0.024
2.409SerTyr: 2.409 ± 0.033
0.0SerXaa: 0.0 ± 0.0
Thr
3.426ThrAla: 3.426 ± 0.056
0.636ThrCys: 0.636 ± 0.018
2.785ThrAsp: 2.785 ± 0.034
2.94ThrGlu: 2.94 ± 0.043
2.296ThrPhe: 2.296 ± 0.031
3.372ThrGly: 3.372 ± 0.058
1.176ThrHis: 1.176 ± 0.023
3.098ThrIle: 3.098 ± 0.048
3.486ThrLys: 3.486 ± 0.035
5.091ThrLeu: 5.091 ± 0.049
1.141ThrMet: 1.141 ± 0.022
2.883ThrAsn: 2.883 ± 0.034
3.144ThrPro: 3.144 ± 0.055
2.028ThrGln: 2.028 ± 0.029
2.48ThrArg: 2.48 ± 0.035
4.916ThrSer: 4.916 ± 0.082
3.701ThrThr: 3.701 ± 0.075
3.538ThrVal: 3.538 ± 0.042
0.578ThrTrp: 0.578 ± 0.019
1.515ThrTyr: 1.515 ± 0.028
0.0ThrXaa: 0.0 ± 0.0
Val
3.772ValAla: 3.772 ± 0.041
0.788ValCys: 0.788 ± 0.02
3.843ValAsp: 3.843 ± 0.041
4.15ValGlu: 4.15 ± 0.043
2.644ValPhe: 2.644 ± 0.035
3.348ValGly: 3.348 ± 0.044
1.305ValHis: 1.305 ± 0.023
3.365ValIle: 3.365 ± 0.041
3.979ValLys: 3.979 ± 0.041
5.706ValLeu: 5.706 ± 0.055
1.196ValMet: 1.196 ± 0.024
3.063ValAsn: 3.063 ± 0.038
3.103ValPro: 3.103 ± 0.04
2.375ValGln: 2.375 ± 0.03
2.749ValArg: 2.749 ± 0.033
4.978ValSer: 4.978 ± 0.048
3.298ValThr: 3.298 ± 0.046
4.103ValVal: 4.103 ± 0.048
0.653ValTrp: 0.653 ± 0.017
1.862ValTyr: 1.862 ± 0.03
0.0ValXaa: 0.0 ± 0.0
Trp
0.575TrpAla: 0.575 ± 0.017
0.238TrpCys: 0.238 ± 0.01
0.709TrpAsp: 0.709 ± 0.018
0.669TrpGlu: 0.669 ± 0.018
0.557TrpPhe: 0.557 ± 0.016
0.594TrpGly: 0.594 ± 0.018
0.232TrpHis: 0.232 ± 0.011
0.676TrpIle: 0.676 ± 0.02
0.859TrpLys: 0.859 ± 0.02
1.012TrpLeu: 1.012 ± 0.021
0.25TrpMet: 0.25 ± 0.009
0.661TrpAsn: 0.661 ± 0.017
0.341TrpPro: 0.341 ± 0.012
0.476TrpGln: 0.476 ± 0.015
0.588TrpArg: 0.588 ± 0.018
0.913TrpSer: 0.913 ± 0.026
0.547TrpThr: 0.547 ± 0.017
0.594TrpVal: 0.594 ± 0.017
0.173TrpTrp: 0.173 ± 0.01
0.404TrpTyr: 0.404 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.813TyrAla: 1.813 ± 0.029
0.521TyrCys: 0.521 ± 0.015
2.078TyrAsp: 2.078 ± 0.025
2.101TyrGlu: 2.101 ± 0.033
1.517TyrPhe: 1.517 ± 0.03
2.05TyrGly: 2.05 ± 0.041
0.882TyrHis: 0.882 ± 0.021
1.683TyrIle: 1.683 ± 0.029
1.973TyrLys: 1.973 ± 0.029
3.256TyrLeu: 3.256 ± 0.042
0.756TyrMet: 0.756 ± 0.019
1.675TyrAsn: 1.675 ± 0.028
1.346TyrPro: 1.346 ± 0.026
1.427TyrGln: 1.427 ± 0.028
1.608TyrArg: 1.608 ± 0.026
2.511TyrSer: 2.511 ± 0.035
1.612TyrThr: 1.612 ± 0.027
2.0TyrVal: 2.0 ± 0.034
0.411TyrTrp: 0.411 ± 0.015
1.325TyrTyr: 1.325 ± 0.026
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4987 proteins (2475090 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski