Amino acid dipepetide frequency for Paxillus rubicundulus Ve08.2h10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.008AlaAla: 7.008 ± 0.043	1.338AlaCys: 1.338 ± 0.017	3.723AlaAsp: 3.723 ± 0.027	4.589AlaGlu: 4.589 ± 0.037	2.988AlaPhe: 2.988 ± 0.026	4.723AlaGly: 4.723 ± 0.034	2.254AlaHis: 2.254 ± 0.021	3.995AlaIle: 3.995 ± 0.03	3.832AlaLys: 3.832 ± 0.029	7.914AlaLeu: 7.914 ± 0.043	1.977AlaMet: 1.977 ± 0.018	2.667AlaAsn: 2.667 ± 0.021	4.649AlaPro: 4.649 ± 0.036	3.35AlaGln: 3.35 ± 0.026	4.64AlaArg: 4.64 ± 0.032	7.038AlaSer: 7.038 ± 0.037	4.936AlaThr: 4.936 ± 0.032	5.048AlaVal: 5.048 ± 0.034	1.222AlaTrp: 1.222 ± 0.017	1.967AlaTyr: 1.967 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	1.178CysAla: 1.178 ± 0.013	0.438CysCys: 0.438 ± 0.01	0.808CysAsp: 0.808 ± 0.014	0.732CysGlu: 0.732 ± 0.01	0.702CysPhe: 0.702 ± 0.012	1.092CysGly: 1.092 ± 0.015	0.595CysHis: 0.595 ± 0.01	0.945CysIle: 0.945 ± 0.013	0.763CysLys: 0.763 ± 0.014	1.671CysLeu: 1.671 ± 0.021	0.439CysMet: 0.439 ± 0.008	0.633CysAsn: 0.633 ± 0.011	1.097CysPro: 1.097 ± 0.017	0.735CysGln: 0.735 ± 0.014	0.958CysArg: 0.958 ± 0.012	1.353CysSer: 1.353 ± 0.017	1.043CysThr: 1.043 ± 0.015	0.977CysVal: 0.977 ± 0.014	0.305CysTrp: 0.305 ± 0.007	0.449CysTyr: 0.449 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.249AspAla: 4.249 ± 0.029	0.77AspCys: 0.77 ± 0.011	3.711AspAsp: 3.711 ± 0.034	3.961AspGlu: 3.961 ± 0.033	1.947AspPhe: 1.947 ± 0.018	3.719AspGly: 3.719 ± 0.026	1.445AspHis: 1.445 ± 0.018	3.076AspIle: 3.076 ± 0.024	2.189AspLys: 2.189 ± 0.02	4.851AspLeu: 4.851 ± 0.028	1.261AspMet: 1.261 ± 0.014	1.853AspAsn: 1.853 ± 0.017	3.269AspPro: 3.269 ± 0.027	1.736AspGln: 1.736 ± 0.016	2.574AspArg: 2.574 ± 0.028	3.822AspSer: 3.822 ± 0.029	2.882AspThr: 2.882 ± 0.023	3.807AspVal: 3.807 ± 0.026	0.843AspTrp: 0.843 ± 0.012	1.359AspTyr: 1.359 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	4.812GluAla: 4.812 ± 0.032	0.794GluCys: 0.794 ± 0.012	3.86GluAsp: 3.86 ± 0.034	5.163GluGlu: 5.163 ± 0.052	1.849GluPhe: 1.849 ± 0.018	3.665GluGly: 3.665 ± 0.029	1.617GluHis: 1.617 ± 0.017	2.586GluIle: 2.586 ± 0.023	2.944GluLys: 2.944 ± 0.028	5.177GluLeu: 5.177 ± 0.038	1.442GluMet: 1.442 ± 0.017	1.877GluAsn: 1.877 ± 0.017	2.483GluPro: 2.483 ± 0.024	2.212GluGln: 2.212 ± 0.023	3.706GluArg: 3.706 ± 0.032	3.821GluSer: 3.821 ± 0.03	2.878GluThr: 2.878 ± 0.023	3.786GluVal: 3.786 ± 0.029	0.958GluTrp: 0.958 ± 0.012	1.433GluTyr: 1.433 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.747PheAla: 2.747 ± 0.025	0.693PheCys: 0.693 ± 0.011	2.028PheAsp: 2.028 ± 0.017	1.849PheGlu: 1.849 ± 0.02	1.494PhePhe: 1.494 ± 0.019	2.445PheGly: 2.445 ± 0.022	1.151PheHis: 1.151 ± 0.015	1.878PheIle: 1.878 ± 0.02	1.556PheLys: 1.556 ± 0.016	3.592PheLeu: 3.592 ± 0.03	0.835PheMet: 0.835 ± 0.012	1.396PheAsn: 1.396 ± 0.016	2.158PhePro: 2.158 ± 0.022	1.51PheGln: 1.51 ± 0.017	1.79PheArg: 1.79 ± 0.017	3.202PheSer: 3.202 ± 0.025	2.2PheThr: 2.2 ± 0.02	2.392PheVal: 2.392 ± 0.025	0.606PheTrp: 0.606 ± 0.011	1.016PheTyr: 1.016 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	4.496GlyAla: 4.496 ± 0.027	1.049GlyCys: 1.049 ± 0.014	3.277GlyAsp: 3.277 ± 0.025	3.437GlyGlu: 3.437 ± 0.027	2.3GlyPhe: 2.3 ± 0.021	4.939GlyGly: 4.939 ± 0.042	1.95GlyHis: 1.95 ± 0.022	3.145GlyIle: 3.145 ± 0.027	3.409GlyLys: 3.409 ± 0.029	5.417GlyLeu: 5.417 ± 0.036	1.593GlyMet: 1.593 ± 0.018	2.165GlyAsn: 2.165 ± 0.019	3.291GlyPro: 3.291 ± 0.029	2.392GlyGln: 2.392 ± 0.023	3.705GlyArg: 3.705 ± 0.033	5.384GlySer: 5.384 ± 0.037	3.851GlyThr: 3.851 ± 0.032	4.1GlyVal: 4.1 ± 0.03	1.138GlyTrp: 1.138 ± 0.017	1.643GlyTyr: 1.643 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	2.384HisAla: 2.384 ± 0.022	0.642HisCys: 0.642 ± 0.012	1.459HisAsp: 1.459 ± 0.015	1.359HisGlu: 1.359 ± 0.015	1.189HisPhe: 1.189 ± 0.015	1.834HisGly: 1.834 ± 0.019	1.208HisHis: 1.208 ± 0.019	1.675HisIle: 1.675 ± 0.019	1.181HisLys: 1.181 ± 0.013	3.112HisLeu: 3.112 ± 0.025	0.662HisMet: 0.662 ± 0.012	1.051HisAsn: 1.051 ± 0.015	2.301HisPro: 2.301 ± 0.024	1.271HisGln: 1.271 ± 0.016	1.733HisArg: 1.733 ± 0.019	2.553HisSer: 2.553 ± 0.024	1.866HisThr: 1.866 ± 0.022	1.839HisVal: 1.839 ± 0.02	0.482HisTrp: 0.482 ± 0.009	0.802HisTyr: 0.802 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.859IleAla: 3.859 ± 0.029	0.967IleCys: 0.967 ± 0.015	2.632IleAsp: 2.632 ± 0.02	2.572IleGlu: 2.572 ± 0.022	1.943IlePhe: 1.943 ± 0.018	2.791IleGly: 2.791 ± 0.023	1.564IleHis: 1.564 ± 0.017	2.574IleIle: 2.574 ± 0.025	2.162IleLys: 2.162 ± 0.021	4.645IleLeu: 4.645 ± 0.035	1.102IleMet: 1.102 ± 0.014	1.848IleAsn: 1.848 ± 0.018	3.498IlePro: 3.498 ± 0.027	2.031IleGln: 2.031 ± 0.022	2.622IleArg: 2.622 ± 0.025	4.266IleSer: 4.266 ± 0.032	2.905IleThr: 2.905 ± 0.023	3.072IleVal: 3.072 ± 0.025	0.814IleTrp: 0.814 ± 0.014	1.307IleTyr: 1.307 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.106LysAla: 4.106 ± 0.034	0.734LysCys: 0.734 ± 0.012	2.496LysAsp: 2.496 ± 0.026	3.148LysGlu: 3.148 ± 0.031	1.47LysPhe: 1.47 ± 0.017	3.096LysGly: 3.096 ± 0.029	1.364LysHis: 1.364 ± 0.016	2.088LysIle: 2.088 ± 0.02	3.204LysLys: 3.204 ± 0.036	4.118LysLeu: 4.118 ± 0.029	1.08LysMet: 1.08 ± 0.014	1.538LysAsn: 1.538 ± 0.02	2.471LysPro: 2.471 ± 0.023	1.877LysGln: 1.877 ± 0.021	3.098LysArg: 3.098 ± 0.027	3.269LysSer: 3.269 ± 0.027	2.557LysThr: 2.557 ± 0.022	2.936LysVal: 2.936 ± 0.023	0.779LysTrp: 0.779 ± 0.011	1.318LysTyr: 1.318 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.741LeuAla: 7.741 ± 0.038	1.716LeuCys: 1.716 ± 0.018	5.104LeuAsp: 5.104 ± 0.029	5.313LeuGlu: 5.313 ± 0.038	3.456LeuPhe: 3.456 ± 0.031	5.603LeuGly: 5.603 ± 0.039	2.998LeuHis: 2.998 ± 0.022	3.958LeuIle: 3.958 ± 0.029	4.235LeuLys: 4.235 ± 0.031	8.987LeuLeu: 8.987 ± 0.06	1.934LeuMet: 1.934 ± 0.019	3.188LeuAsn: 3.188 ± 0.027	6.421LeuPro: 6.421 ± 0.041	4.148LeuGln: 4.148 ± 0.03	5.52LeuArg: 5.52 ± 0.038	8.185LeuSer: 8.185 ± 0.041	5.432LeuThr: 5.432 ± 0.035	5.784LeuVal: 5.784 ± 0.04	1.356LeuTrp: 1.356 ± 0.017	2.299LeuTyr: 2.299 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.967MetAla: 1.967 ± 0.017	0.349MetCys: 0.349 ± 0.008	1.446MetAsp: 1.446 ± 0.016	1.398MetGlu: 1.398 ± 0.015	0.808MetPhe: 0.808 ± 0.01	1.411MetGly: 1.411 ± 0.018	0.733MetHis: 0.733 ± 0.011	1.014MetIle: 1.014 ± 0.012	1.117MetLys: 1.117 ± 0.014	2.071MetLeu: 2.071 ± 0.018	0.583MetMet: 0.583 ± 0.01	0.83MetAsn: 0.83 ± 0.014	1.355MetPro: 1.355 ± 0.017	1.04MetGln: 1.04 ± 0.014	1.197MetArg: 1.197 ± 0.016	2.128MetSer: 2.128 ± 0.02	1.349MetThr: 1.349 ± 0.015	1.482MetVal: 1.482 ± 0.019	0.352MetTrp: 0.352 ± 0.008	0.54MetTyr: 0.54 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.883AsnAla: 2.883 ± 0.024	0.572AsnCys: 0.572 ± 0.011	1.793AsnAsp: 1.793 ± 0.018	1.858AsnGlu: 1.858 ± 0.019	1.376AsnPhe: 1.376 ± 0.017	2.458AsnGly: 2.458 ± 0.023	1.05AsnHis: 1.05 ± 0.013	2.033AsnIle: 2.033 ± 0.021	1.539AsnLys: 1.539 ± 0.018	3.265AsnLeu: 3.265 ± 0.026	0.847AsnMet: 0.847 ± 0.013	1.417AsnAsn: 1.417 ± 0.02	2.363AsnPro: 2.363 ± 0.022	1.303AsnGln: 1.303 ± 0.016	1.607AsnArg: 1.607 ± 0.016	2.652AsnSer: 2.652 ± 0.024	2.144AsnThr: 2.144 ± 0.016	2.398AsnVal: 2.398 ± 0.021	0.547AsnTrp: 0.547 ± 0.012	0.895AsnTyr: 0.895 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.905ProAla: 4.905 ± 0.038	0.854ProCys: 0.854 ± 0.015	3.107ProAsp: 3.107 ± 0.023	3.261ProGlu: 3.261 ± 0.026	2.251ProPhe: 2.251 ± 0.02	3.679ProGly: 3.679 ± 0.03	1.989ProHis: 1.989 ± 0.022	2.839ProIle: 2.839 ± 0.023	2.536ProLys: 2.536 ± 0.026	5.697ProLeu: 5.697 ± 0.034	1.248ProMet: 1.248 ± 0.016	2.22ProAsn: 2.22 ± 0.02	6.446ProPro: 6.446 ± 0.065	2.559ProGln: 2.559 ± 0.028	3.448ProArg: 3.448 ± 0.032	7.53ProSer: 7.53 ± 0.06	4.519ProThr: 4.519 ± 0.033	3.781ProVal: 3.781 ± 0.026	0.81ProTrp: 0.81 ± 0.013	1.572ProTyr: 1.572 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.428GlnAla: 3.428 ± 0.028	0.745GlnCys: 0.745 ± 0.013	1.967GlnAsp: 1.967 ± 0.019	2.369GlnGlu: 2.369 ± 0.022	1.27GlnPhe: 1.27 ± 0.016	2.456GlnGly: 2.456 ± 0.022	1.328GlnHis: 1.328 ± 0.018	1.882GlnIle: 1.882 ± 0.022	1.878GlnLys: 1.878 ± 0.02	3.798GlnLeu: 3.798 ± 0.028	0.96GlnMet: 0.96 ± 0.013	1.38GlnAsn: 1.38 ± 0.015	2.658GlnPro: 2.658 ± 0.029	2.072GlnGln: 2.072 ± 0.027	2.456GlnArg: 2.456 ± 0.023	3.289GlnSer: 3.289 ± 0.025	2.301GlnThr: 2.301 ± 0.022	2.506GlnVal: 2.506 ± 0.021	0.713GlnTrp: 0.713 ± 0.012	1.093GlnTyr: 1.093 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.584ArgAla: 4.584 ± 0.031	0.95ArgCys: 0.95 ± 0.012	2.936ArgAsp: 2.936 ± 0.031	3.455ArgGlu: 3.455 ± 0.032	1.944ArgPhe: 1.944 ± 0.022	3.476ArgGly: 3.476 ± 0.031	1.695ArgHis: 1.695 ± 0.018	2.689ArgIle: 2.689 ± 0.02	3.147ArgLys: 3.147 ± 0.026	5.14ArgLeu: 5.14 ± 0.032	1.353ArgMet: 1.353 ± 0.016	1.976ArgAsn: 1.976 ± 0.017	3.441ArgPro: 3.441 ± 0.029	2.312ArgGln: 2.312 ± 0.023	4.565ArgArg: 4.565 ± 0.039	4.8ArgSer: 4.8 ± 0.034	3.321ArgThr: 3.321 ± 0.027	3.473ArgVal: 3.473 ± 0.026	0.941ArgTrp: 0.941 ± 0.015	1.482ArgTyr: 1.482 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.661SerAla: 6.661 ± 0.042	1.311SerCys: 1.311 ± 0.018	4.298SerAsp: 4.298 ± 0.03	3.959SerGlu: 3.959 ± 0.028	3.103SerPhe: 3.103 ± 0.026	5.384SerGly: 5.384 ± 0.036	2.612SerHis: 2.612 ± 0.026	4.207SerIle: 4.207 ± 0.03	3.664SerLys: 3.664 ± 0.031	8.086SerLeu: 8.086 ± 0.047	1.923SerMet: 1.923 ± 0.019	2.98SerAsn: 2.98 ± 0.023	6.41SerPro: 6.41 ± 0.054	3.554SerGln: 3.554 ± 0.027	5.015SerArg: 5.015 ± 0.039	9.666SerSer: 9.666 ± 0.067	6.173SerThr: 6.173 ± 0.036	5.023SerVal: 5.023 ± 0.03	1.135SerTrp: 1.135 ± 0.014	1.917SerTyr: 1.917 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	4.794ThrAla: 4.794 ± 0.03	1.094ThrCys: 1.094 ± 0.017	2.643ThrAsp: 2.643 ± 0.02	2.748ThrGlu: 2.748 ± 0.02	2.382ThrPhe: 2.382 ± 0.021	3.626ThrGly: 3.626 ± 0.028	1.794ThrHis: 1.794 ± 0.018	3.17ThrIle: 3.17 ± 0.023	2.605ThrLys: 2.605 ± 0.023	5.875ThrLeu: 5.875 ± 0.032	1.338ThrMet: 1.338 ± 0.018	2.097ThrAsn: 2.097 ± 0.022	4.648ThrPro: 4.648 ± 0.036	2.273ThrGln: 2.273 ± 0.019	3.288ThrArg: 3.288 ± 0.025	6.055ThrSer: 6.055 ± 0.04	4.293ThrThr: 4.293 ± 0.037	3.647ThrVal: 3.647 ± 0.029	0.915ThrTrp: 0.915 ± 0.013	1.551ThrTyr: 1.551 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	4.911ValAla: 4.911 ± 0.03	1.067ValCys: 1.067 ± 0.013	3.678ValAsp: 3.678 ± 0.027	3.708ValGlu: 3.708 ± 0.026	2.399ValPhe: 2.399 ± 0.02	3.721ValGly: 3.721 ± 0.03	1.888ValHis: 1.888 ± 0.019	3.292ValIle: 3.292 ± 0.026	2.833ValLys: 2.833 ± 0.022	6.042ValLeu: 6.042 ± 0.03	1.506ValMet: 1.506 ± 0.017	2.228ValAsn: 2.228 ± 0.018	4.098ValPro: 4.098 ± 0.027	2.512ValGln: 2.512 ± 0.021	3.376ValArg: 3.376 ± 0.029	4.931ValSer: 4.931 ± 0.029	3.688ValThr: 3.688 ± 0.027	4.492ValVal: 4.492 ± 0.035	0.99ValTrp: 0.99 ± 0.014	1.642ValTyr: 1.642 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.207TrpAla: 1.207 ± 0.015	0.319TrpCys: 0.319 ± 0.008	0.941TrpAsp: 0.941 ± 0.016	0.933TrpGlu: 0.933 ± 0.012	0.581TrpPhe: 0.581 ± 0.01	0.902TrpGly: 0.902 ± 0.015	0.487TrpHis: 0.487 ± 0.01	0.75TrpIle: 0.75 ± 0.011	0.904TrpLys: 0.904 ± 0.016	1.365TrpLeu: 1.365 ± 0.015	0.474TrpMet: 0.474 ± 0.009	0.648TrpAsn: 0.648 ± 0.012	0.686TrpPro: 0.686 ± 0.01	0.634TrpGln: 0.634 ± 0.011	0.982TrpArg: 0.982 ± 0.013	1.197TrpSer: 1.197 ± 0.016	0.988TrpThr: 0.988 ± 0.014	0.917TrpVal: 0.917 ± 0.014	0.328TrpTrp: 0.328 ± 0.007	0.409TrpTyr: 0.409 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.936TyrAla: 1.936 ± 0.018	0.512TyrCys: 0.512 ± 0.011	1.418TyrAsp: 1.418 ± 0.016	1.251TyrGlu: 1.251 ± 0.016	1.085TyrPhe: 1.085 ± 0.015	1.662TyrGly: 1.662 ± 0.02	0.88TyrHis: 0.88 ± 0.013	1.378TyrIle: 1.378 ± 0.014	1.049TyrLys: 1.049 ± 0.014	2.554TyrLeu: 2.554 ± 0.025	0.614TyrMet: 0.614 ± 0.011	1.007TyrAsn: 1.007 ± 0.014	1.504TyrPro: 1.504 ± 0.021	1.029TyrGln: 1.029 ± 0.016	1.402TyrArg: 1.402 ± 0.014	1.94TyrSer: 1.94 ± 0.02	1.511TyrThr: 1.511 ± 0.018	1.543TyrVal: 1.543 ± 0.019	0.417TyrTrp: 0.417 ± 0.009	0.809TyrTyr: 0.809 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 21906 proteins (5778669 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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