Amino acid dipepetide frequency for Tremella mesenterica (strain ATCC 24925 / CBS 8224 / DSM 1558 / NBRC 9311 / NRRL Y-6157 / RJB 2259-6 / UBC 559-6) (Jelly fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.415AlaAla: 6.415 ± 0.205
0.939AlaCys: 0.939 ± 0.043
2.904AlaAsp: 2.904 ± 0.061
4.052AlaGlu: 4.052 ± 0.09
2.3AlaPhe: 2.3 ± 0.074
4.578AlaGly: 4.578 ± 0.109
1.464AlaHis: 1.464 ± 0.052
3.404AlaIle: 3.404 ± 0.072
3.198AlaLys: 3.198 ± 0.086
6.697AlaLeu: 6.697 ± 0.139
1.699AlaMet: 1.699 ± 0.059
2.053AlaAsn: 2.053 ± 0.065
3.953AlaPro: 3.953 ± 0.12
2.785AlaGln: 2.785 ± 0.066
4.221AlaArg: 4.221 ± 0.09
5.97AlaSer: 5.97 ± 0.126
3.935AlaThr: 3.935 ± 0.085
4.343AlaVal: 4.343 ± 0.104
1.054AlaTrp: 1.054 ± 0.048
1.705AlaTyr: 1.705 ± 0.055
0.0AlaXaa: 0.0 ± 0.0
Cys
0.737CysAla: 0.737 ± 0.036
0.209CysCys: 0.209 ± 0.021
0.698CysAsp: 0.698 ± 0.035
0.578CysGlu: 0.578 ± 0.032
0.404CysPhe: 0.404 ± 0.026
0.957CysGly: 0.957 ± 0.052
0.354CysHis: 0.354 ± 0.025
0.597CysIle: 0.597 ± 0.032
0.447CysLys: 0.447 ± 0.028
1.33CysLeu: 1.33 ± 0.051
0.251CysMet: 0.251 ± 0.02
0.331CysAsn: 0.331 ± 0.025
0.849CysPro: 0.849 ± 0.061
0.536CysGln: 0.536 ± 0.034
0.687CysArg: 0.687 ± 0.032
0.993CysSer: 0.993 ± 0.048
0.75CysThr: 0.75 ± 0.04
0.766CysVal: 0.766 ± 0.04
0.193CysTrp: 0.193 ± 0.02
0.302CysTyr: 0.302 ± 0.024
0.0CysXaa: 0.0 ± 0.0
Asp
3.187AspAla: 3.187 ± 0.079
0.561AspCys: 0.561 ± 0.032
4.388AspAsp: 4.388 ± 0.154
4.636AspGlu: 4.636 ± 0.122
1.922AspPhe: 1.922 ± 0.059
4.17AspGly: 4.17 ± 0.085
1.507AspHis: 1.507 ± 0.087
2.571AspIle: 2.571 ± 0.075
2.574AspLys: 2.574 ± 0.077
5.034AspLeu: 5.034 ± 0.092
1.332AspMet: 1.332 ± 0.042
1.795AspAsn: 1.795 ± 0.056
3.478AspPro: 3.478 ± 0.095
2.214AspGln: 2.214 ± 0.066
3.444AspArg: 3.444 ± 0.091
3.994AspSer: 3.994 ± 0.083
3.142AspThr: 3.142 ± 0.065
3.8AspVal: 3.8 ± 0.085
1.002AspTrp: 1.002 ± 0.051
1.332AspTyr: 1.332 ± 0.048
0.0AspXaa: 0.0 ± 0.0
Glu
4.237GluAla: 4.237 ± 0.097
0.687GluCys: 0.687 ± 0.029
4.567GluAsp: 4.567 ± 0.108
7.451GluGlu: 7.451 ± 0.223
1.75GluPhe: 1.75 ± 0.056
4.741GluGly: 4.741 ± 0.11
1.438GluHis: 1.438 ± 0.054
3.304GluIle: 3.304 ± 0.086
4.223GluLys: 4.223 ± 0.123
4.94GluLeu: 4.94 ± 0.098
1.781GluMet: 1.781 ± 0.061
2.538GluAsn: 2.538 ± 0.076
2.473GluPro: 2.473 ± 0.067
2.384GluGln: 2.384 ± 0.089
4.462GluArg: 4.462 ± 0.102
4.218GluSer: 4.218 ± 0.092
3.814GluThr: 3.814 ± 0.098
4.17GluVal: 4.17 ± 0.1
1.067GluTrp: 1.067 ± 0.05
1.577GluTyr: 1.577 ± 0.055
0.0GluXaa: 0.0 ± 0.0
Phe
2.228PheAla: 2.228 ± 0.066
0.499PheCys: 0.499 ± 0.027
2.014PheAsp: 2.014 ± 0.055
2.029PheGlu: 2.029 ± 0.066
1.202PhePhe: 1.202 ± 0.047
2.484PheGly: 2.484 ± 0.07
0.968PheHis: 0.968 ± 0.04
1.559PheIle: 1.559 ± 0.055
1.345PheLys: 1.345 ± 0.051
3.084PheLeu: 3.084 ± 0.082
0.645PheMet: 0.645 ± 0.034
1.187PheAsn: 1.187 ± 0.046
2.103PhePro: 2.103 ± 0.058
1.184PheGln: 1.184 ± 0.045
1.766PheArg: 1.766 ± 0.052
2.852PheSer: 2.852 ± 0.072
1.715PheThr: 1.715 ± 0.058
1.958PheVal: 1.958 ± 0.06
0.484PheTrp: 0.484 ± 0.031
0.796PheTyr: 0.796 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
3.817GlyAla: 3.817 ± 0.09
0.845GlyCys: 0.845 ± 0.043
3.727GlyAsp: 3.727 ± 0.086
4.911GlyGlu: 4.911 ± 0.107
2.259GlyPhe: 2.259 ± 0.065
6.177GlyGly: 6.177 ± 0.184
1.726GlyHis: 1.726 ± 0.066
3.068GlyIle: 3.068 ± 0.083
4.255GlyLys: 4.255 ± 0.088
6.11GlyLeu: 6.11 ± 0.128
1.869GlyMet: 1.869 ± 0.076
2.313GlyAsn: 2.313 ± 0.071
3.611GlyPro: 3.611 ± 0.091
2.865GlyGln: 2.865 ± 0.081
4.456GlyArg: 4.456 ± 0.106
5.799GlySer: 5.799 ± 0.124
3.837GlyThr: 3.837 ± 0.087
4.3GlyVal: 4.3 ± 0.108
1.338GlyTrp: 1.338 ± 0.05
1.768GlyTyr: 1.768 ± 0.059
0.0GlyXaa: 0.0 ± 0.0
His
1.425HisAla: 1.425 ± 0.054
0.291HisCys: 0.291 ± 0.027
1.467HisAsp: 1.467 ± 0.081
1.309HisGlu: 1.309 ± 0.054
0.851HisPhe: 0.851 ± 0.038
1.594HisGly: 1.594 ± 0.051
0.933HisHis: 0.933 ± 0.055
1.181HisIle: 1.181 ± 0.041
0.885HisLys: 0.885 ± 0.038
2.725HisLeu: 2.725 ± 0.076
0.475HisMet: 0.475 ± 0.029
0.817HisAsn: 0.817 ± 0.034
2.209HisPro: 2.209 ± 0.074
1.004HisGln: 1.004 ± 0.045
1.525HisArg: 1.525 ± 0.053
2.32HisSer: 2.32 ± 0.084
1.615HisThr: 1.615 ± 0.053
1.478HisVal: 1.478 ± 0.056
0.335HisTrp: 0.335 ± 0.023
0.661HisTyr: 0.661 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
3.198IleAla: 3.198 ± 0.079
0.627IleCys: 0.627 ± 0.041
2.83IleAsp: 2.83 ± 0.076
2.572IleGlu: 2.572 ± 0.064
1.581IlePhe: 1.581 ± 0.056
3.018IleGly: 3.018 ± 0.078
1.311IleHis: 1.311 ± 0.046
2.498IleIle: 2.498 ± 0.076
2.178IleLys: 2.178 ± 0.059
4.393IleLeu: 4.393 ± 0.089
0.912IleMet: 0.912 ± 0.045
1.687IleAsn: 1.687 ± 0.063
4.101IlePro: 4.101 ± 0.104
1.858IleGln: 1.858 ± 0.053
3.003IleArg: 3.003 ± 0.079
4.454IleSer: 4.454 ± 0.085
3.052IleThr: 3.052 ± 0.08
2.748IleVal: 2.748 ± 0.069
0.627IleTrp: 0.627 ± 0.032
1.234IleTyr: 1.234 ± 0.045
0.0IleXaa: 0.0 ± 0.0
Lys
3.447LysAla: 3.447 ± 0.085
0.534LysCys: 0.534 ± 0.038
2.875LysAsp: 2.875 ± 0.073
4.147LysGlu: 4.147 ± 0.116
1.208LysPhe: 1.208 ± 0.039
3.763LysGly: 3.763 ± 0.089
1.039LysHis: 1.039 ± 0.049
2.127LysIle: 2.127 ± 0.065
3.179LysLys: 3.179 ± 0.118
3.616LysLeu: 3.616 ± 0.089
1.118LysMet: 1.118 ± 0.043
1.604LysAsn: 1.604 ± 0.057
2.448LysPro: 2.448 ± 0.077
1.57LysGln: 1.57 ± 0.053
3.751LysArg: 3.751 ± 0.103
3.817LysSer: 3.817 ± 0.096
2.88LysThr: 2.88 ± 0.077
3.29LysVal: 3.29 ± 0.08
0.708LysTrp: 0.708 ± 0.035
1.189LysTyr: 1.189 ± 0.051
0.0LysXaa: 0.0 ± 0.0
Leu
6.478LeuAla: 6.478 ± 0.137
1.178LeuCys: 1.178 ± 0.045
5.235LeuAsp: 5.235 ± 0.091
5.389LeuGlu: 5.389 ± 0.104
2.957LeuPhe: 2.957 ± 0.084
6.037LeuGly: 6.037 ± 0.132
2.252LeuHis: 2.252 ± 0.057
4.158LeuIle: 4.158 ± 0.104
4.102LeuLys: 4.102 ± 0.085
8.277LeuLeu: 8.277 ± 0.168
1.543LeuMet: 1.543 ± 0.045
3.045LeuAsn: 3.045 ± 0.074
6.853LeuPro: 6.853 ± 0.137
3.291LeuGln: 3.291 ± 0.093
5.95LeuArg: 5.95 ± 0.111
8.964LeuSer: 8.964 ± 0.121
5.421LeuThr: 5.421 ± 0.102
5.378LeuVal: 5.378 ± 0.118
1.234LeuTrp: 1.234 ± 0.042
2.078LeuTyr: 2.078 ± 0.067
0.0LeuXaa: 0.0 ± 0.0
Met
1.686MetAla: 1.686 ± 0.046
0.206MetCys: 0.206 ± 0.02
1.192MetAsp: 1.192 ± 0.041
1.459MetGlu: 1.459 ± 0.052
0.68MetPhe: 0.68 ± 0.037
1.554MetGly: 1.554 ± 0.069
0.291MetHis: 0.291 ± 0.02
1.067MetIle: 1.067 ± 0.048
1.104MetLys: 1.104 ± 0.039
1.692MetLeu: 1.692 ± 0.054
0.65MetMet: 0.65 ± 0.036
0.909MetAsn: 0.909 ± 0.036
1.039MetPro: 1.039 ± 0.045
0.676MetGln: 0.676 ± 0.033
1.404MetArg: 1.404 ± 0.049
2.318MetSer: 2.318 ± 0.063
1.654MetThr: 1.654 ± 0.048
1.47MetVal: 1.47 ± 0.058
0.28MetTrp: 0.28 ± 0.02
0.539MetTyr: 0.539 ± 0.034
0.0MetXaa: 0.0 ± 0.0
Asn
2.334AsnAla: 2.334 ± 0.068
0.372AsnCys: 0.372 ± 0.026
2.12AsnAsp: 2.12 ± 0.057
2.205AsnGlu: 2.205 ± 0.06
1.155AsnPhe: 1.155 ± 0.041
2.555AsnGly: 2.555 ± 0.073
0.965AsnHis: 0.965 ± 0.044
1.752AsnIle: 1.752 ± 0.052
1.554AsnLys: 1.554 ± 0.05
3.256AsnLeu: 3.256 ± 0.083
0.793AsnMet: 0.793 ± 0.037
1.343AsnAsn: 1.343 ± 0.072
2.664AsnPro: 2.664 ± 0.07
1.509AsnGln: 1.509 ± 0.058
1.964AsnArg: 1.964 ± 0.062
2.859AsnSer: 2.859 ± 0.075
2.251AsnThr: 2.251 ± 0.071
2.3AsnVal: 2.3 ± 0.061
0.468AsnTrp: 0.468 ± 0.027
0.761AsnTyr: 0.761 ± 0.036
0.0AsnXaa: 0.0 ± 0.0
Pro
4.44ProAla: 4.44 ± 0.159
0.623ProCys: 0.623 ± 0.034
3.166ProAsp: 3.166 ± 0.073
3.571ProGlu: 3.571 ± 0.085
2.362ProPhe: 2.362 ± 0.078
3.628ProGly: 3.628 ± 0.094
1.761ProHis: 1.761 ± 0.069
3.167ProIle: 3.167 ± 0.099
2.592ProLys: 2.592 ± 0.066
6.045ProLeu: 6.045 ± 0.12
1.144ProMet: 1.144 ± 0.047
2.518ProAsn: 2.518 ± 0.077
7.624ProPro: 7.624 ± 0.243
2.389ProGln: 2.389 ± 0.072
4.006ProArg: 4.006 ± 0.1
8.968ProSer: 8.968 ± 0.221
5.104ProThr: 5.104 ± 0.115
3.851ProVal: 3.851 ± 0.099
0.74ProTrp: 0.74 ± 0.033
1.466ProTyr: 1.466 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
3.016GlnAla: 3.016 ± 0.066
0.384GlnCys: 0.384 ± 0.027
2.016GlnAsp: 2.016 ± 0.059
2.342GlnGlu: 2.342 ± 0.077
0.986GlnPhe: 0.986 ± 0.043
2.714GlnGly: 2.714 ± 0.082
0.996GlnHis: 0.996 ± 0.041
1.848GlnIle: 1.848 ± 0.055
1.634GlnLys: 1.634 ± 0.05
3.301GlnLeu: 3.301 ± 0.082
0.885GlnMet: 0.885 ± 0.038
1.446GlnAsn: 1.446 ± 0.054
2.481GlnPro: 2.481 ± 0.084
1.969GlnGln: 1.969 ± 0.086
2.556GlnArg: 2.556 ± 0.06
3.539GlnSer: 3.539 ± 0.093
2.698GlnThr: 2.698 ± 0.062
2.426GlnVal: 2.426 ± 0.061
0.532GlnTrp: 0.532 ± 0.031
0.956GlnTyr: 0.956 ± 0.041
0.0GlnXaa: 0.0 ± 0.0
Arg
4.112ArgAla: 4.112 ± 0.085
0.808ArgCys: 0.808 ± 0.043
3.343ArgAsp: 3.343 ± 0.086
4.295ArgGlu: 4.295 ± 0.104
1.959ArgPhe: 1.959 ± 0.049
3.969ArgGly: 3.969 ± 0.108
1.618ArgHis: 1.618 ± 0.053
3.032ArgIle: 3.032 ± 0.064
3.703ArgLys: 3.703 ± 0.088
6.016ArgLeu: 6.016 ± 0.103
1.53ArgMet: 1.53 ± 0.051
2.119ArgAsn: 2.119 ± 0.056
4.371ArgPro: 4.371 ± 0.117
2.572ArgGln: 2.572 ± 0.069
6.005ArgArg: 6.005 ± 0.156
5.518ArgSer: 5.518 ± 0.15
3.882ArgThr: 3.882 ± 0.077
3.62ArgVal: 3.62 ± 0.08
1.03ArgTrp: 1.03 ± 0.045
1.564ArgTyr: 1.564 ± 0.049
0.0ArgXaa: 0.0 ± 0.0
Ser
6.078SerAla: 6.078 ± 0.134
0.991SerCys: 0.991 ± 0.047
4.549SerAsp: 4.549 ± 0.105
4.68SerGlu: 4.68 ± 0.089
2.855SerPhe: 2.855 ± 0.071
5.941SerGly: 5.941 ± 0.11
2.477SerHis: 2.477 ± 0.071
4.38SerIle: 4.38 ± 0.098
3.896SerLys: 3.896 ± 0.082
8.605SerLeu: 8.605 ± 0.144
1.823SerMet: 1.823 ± 0.072
3.533SerAsn: 3.533 ± 0.088
7.39SerPro: 7.39 ± 0.198
3.739SerGln: 3.739 ± 0.093
5.798SerArg: 5.798 ± 0.127
12.168SerSer: 12.168 ± 0.257
7.207SerThr: 7.207 ± 0.142
4.755SerVal: 4.755 ± 0.082
0.989SerTrp: 0.989 ± 0.039
1.81SerTyr: 1.81 ± 0.06
0.0SerXaa: 0.0 ± 0.0
Thr
4.183ThrAla: 4.183 ± 0.099
0.832ThrCys: 0.832 ± 0.046
2.812ThrAsp: 2.812 ± 0.073
3.2ThrGlu: 3.2 ± 0.068
2.288ThrPhe: 2.288 ± 0.067
4.158ThrGly: 4.158 ± 0.1
1.575ThrHis: 1.575 ± 0.06
3.196ThrIle: 3.196 ± 0.069
2.53ThrLys: 2.53 ± 0.077
5.881ThrLeu: 5.881 ± 0.103
1.192ThrMet: 1.192 ± 0.048
2.278ThrAsn: 2.278 ± 0.067
5.511ThrPro: 5.511 ± 0.139
2.416ThrGln: 2.416 ± 0.07
3.626ThrArg: 3.626 ± 0.075
7.022ThrSer: 7.022 ± 0.118
4.516ThrThr: 4.516 ± 0.109
3.711ThrVal: 3.711 ± 0.096
0.893ThrTrp: 0.893 ± 0.041
1.565ThrTyr: 1.565 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
3.938ValAla: 3.938 ± 0.097
0.79ValCys: 0.79 ± 0.034
3.793ValAsp: 3.793 ± 0.082
4.458ValGlu: 4.458 ± 0.086
1.974ValPhe: 1.974 ± 0.061
4.398ValGly: 4.398 ± 0.081
1.441ValHis: 1.441 ± 0.048
3.008ValIle: 3.008 ± 0.08
3.153ValLys: 3.153 ± 0.087
5.302ValLeu: 5.302 ± 0.117
1.343ValMet: 1.343 ± 0.053
2.146ValAsn: 2.146 ± 0.064
3.97ValPro: 3.97 ± 0.088
2.226ValGln: 2.226 ± 0.061
3.994ValArg: 3.994 ± 0.078
4.934ValSer: 4.934 ± 0.106
3.505ValThr: 3.505 ± 0.086
4.331ValVal: 4.331 ± 0.103
0.859ValTrp: 0.859 ± 0.044
1.406ValTyr: 1.406 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
1.134TrpAla: 1.134 ± 0.064
0.193TrpCys: 0.193 ± 0.018
0.843TrpAsp: 0.843 ± 0.041
1.102TrpGlu: 1.102 ± 0.048
0.504TrpPhe: 0.504 ± 0.029
0.891TrpGly: 0.891 ± 0.043
0.309TrpHis: 0.309 ± 0.023
0.729TrpIle: 0.729 ± 0.04
0.758TrpLys: 0.758 ± 0.035
1.202TrpLeu: 1.202 ± 0.044
0.368TrpMet: 0.368 ± 0.025
0.605TrpAsn: 0.605 ± 0.036
0.565TrpPro: 0.565 ± 0.033
0.524TrpGln: 0.524 ± 0.026
1.141TrpArg: 1.141 ± 0.051
1.099TrpSer: 1.099 ± 0.045
0.941TrpThr: 0.941 ± 0.04
0.935TrpVal: 0.935 ± 0.045
0.283TrpTrp: 0.283 ± 0.021
0.343TrpTyr: 0.343 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.578TyrAla: 1.578 ± 0.056
0.401TyrCys: 0.401 ± 0.027
1.546TyrAsp: 1.546 ± 0.054
1.435TyrGlu: 1.435 ± 0.059
0.904TyrPhe: 0.904 ± 0.043
1.726TyrGly: 1.726 ± 0.061
0.672TyrHis: 0.672 ± 0.031
1.237TyrIle: 1.237 ± 0.046
1.001TyrLys: 1.001 ± 0.046
2.313TyrLeu: 2.313 ± 0.064
0.516TyrMet: 0.516 ± 0.028
0.912TyrAsn: 0.912 ± 0.033
1.472TyrPro: 1.472 ± 0.055
1.015TyrGln: 1.015 ± 0.041
1.303TyrArg: 1.303 ± 0.046
1.858TyrSer: 1.858 ± 0.067
1.469TyrThr: 1.469 ± 0.059
1.342TyrVal: 1.342 ± 0.049
0.351TyrTrp: 0.351 ± 0.021
0.65TyrTyr: 0.65 ± 0.035
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1453 proteins (621631 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski