Amino acid dipepetide frequency for Taro vein chlorosis virus (TAVCV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.937AlaAla: 3.937 ± 1.385
1.05AlaCys: 1.05 ± 0.411
1.837AlaAsp: 1.837 ± 1.39
2.362AlaGlu: 2.362 ± 1.247
1.575AlaPhe: 1.575 ± 0.719
3.937AlaGly: 3.937 ± 1.873
0.525AlaHis: 0.525 ± 0.314
2.887AlaIle: 2.887 ± 1.651
2.625AlaLys: 2.625 ± 1.293
7.349AlaLeu: 7.349 ± 0.97
1.05AlaMet: 1.05 ± 0.502
0.787AlaAsn: 0.787 ± 0.471
2.625AlaPro: 2.625 ± 0.839
1.05AlaGln: 1.05 ± 0.629
3.15AlaArg: 3.15 ± 0.716
5.249AlaSer: 5.249 ± 1.057
4.724AlaThr: 4.724 ± 1.508
5.774AlaVal: 5.774 ± 1.013
0.787AlaTrp: 0.787 ± 0.293
2.625AlaTyr: 2.625 ± 0.476
0.0AlaXaa: 0.0 ± 0.0
Cys
1.05CysAla: 1.05 ± 0.546
0.525CysCys: 0.525 ± 0.273
1.05CysAsp: 1.05 ± 0.411
1.05CysGlu: 1.05 ± 0.856
0.525CysPhe: 0.525 ± 0.273
1.312CysGly: 1.312 ± 0.671
0.262CysHis: 0.262 ± 0.388
0.525CysIle: 0.525 ± 0.298
0.787CysLys: 0.787 ± 0.338
1.575CysLeu: 1.575 ± 0.48
0.262CysMet: 0.262 ± 0.157
0.262CysAsn: 0.262 ± 0.157
1.05CysPro: 1.05 ± 0.621
1.575CysGln: 1.575 ± 0.543
0.787CysArg: 0.787 ± 0.326
2.1CysSer: 2.1 ± 0.681
1.05CysThr: 1.05 ± 0.281
1.575CysVal: 1.575 ± 0.543
0.262CysTrp: 0.262 ± 0.157
0.525CysTyr: 0.525 ± 0.229
0.0CysXaa: 0.0 ± 0.0
Asp
3.937AspAla: 3.937 ± 1.361
1.05AspCys: 1.05 ± 0.387
3.412AspAsp: 3.412 ± 0.589
1.837AspGlu: 1.837 ± 0.848
1.837AspPhe: 1.837 ± 0.45
1.312AspGly: 1.312 ± 0.452
1.575AspHis: 1.575 ± 0.545
4.462AspIle: 4.462 ± 1.424
4.199AspLys: 4.199 ± 0.615
5.249AspLeu: 5.249 ± 0.802
1.575AspMet: 1.575 ± 0.747
3.412AspAsn: 3.412 ± 1.154
4.724AspPro: 4.724 ± 0.633
1.05AspGln: 1.05 ± 0.909
3.15AspArg: 3.15 ± 0.804
4.724AspSer: 4.724 ± 1.646
2.887AspThr: 2.887 ± 1.323
2.887AspVal: 2.887 ± 0.705
1.575AspTrp: 1.575 ± 0.592
1.837AspTyr: 1.837 ± 0.41
0.0AspXaa: 0.0 ± 0.0
Glu
3.15GluAla: 3.15 ± 1.234
1.575GluCys: 1.575 ± 0.752
3.412GluAsp: 3.412 ± 1.462
4.724GluGlu: 4.724 ± 1.334
1.05GluPhe: 1.05 ± 0.525
3.937GluGly: 3.937 ± 0.661
0.787GluHis: 0.787 ± 0.534
4.724GluIle: 4.724 ± 0.601
3.15GluLys: 3.15 ± 0.658
6.824GluLeu: 6.824 ± 1.003
1.312GluMet: 1.312 ± 0.564
1.837GluAsn: 1.837 ± 0.905
1.312GluPro: 1.312 ± 0.63
0.525GluGln: 0.525 ± 0.365
3.675GluArg: 3.675 ± 1.219
4.199GluSer: 4.199 ± 0.649
2.887GluThr: 2.887 ± 0.422
3.15GluVal: 3.15 ± 1.148
0.525GluTrp: 0.525 ± 0.592
1.575GluTyr: 1.575 ± 0.943
0.0GluXaa: 0.0 ± 0.0
Phe
1.312PheAla: 1.312 ± 0.375
0.0PheCys: 0.0 ± 0.0
1.312PheAsp: 1.312 ± 0.547
0.525PheGlu: 0.525 ± 0.229
1.312PhePhe: 1.312 ± 0.575
2.362PheGly: 2.362 ± 0.565
0.262PheHis: 0.262 ± 0.157
2.362PheIle: 2.362 ± 0.371
1.837PheLys: 1.837 ± 0.45
4.199PheLeu: 4.199 ± 1.155
0.787PheMet: 0.787 ± 0.621
1.05PheAsn: 1.05 ± 0.387
2.362PhePro: 2.362 ± 0.771
0.787PheGln: 0.787 ± 0.409
1.05PheArg: 1.05 ± 0.328
2.887PheSer: 2.887 ± 0.627
2.1PheThr: 2.1 ± 0.504
0.787PheVal: 0.787 ± 0.293
0.787PheTrp: 0.787 ± 0.626
1.05PheTyr: 1.05 ± 0.281
0.0PheXaa: 0.0 ± 0.0
Gly
3.412GlyAla: 3.412 ± 0.83
1.05GlyCys: 1.05 ± 0.458
4.462GlyAsp: 4.462 ± 1.36
3.675GlyGlu: 3.675 ± 1.374
2.362GlyPhe: 2.362 ± 0.545
3.675GlyGly: 3.675 ± 0.834
1.575GlyHis: 1.575 ± 0.415
5.249GlyIle: 5.249 ± 0.895
3.412GlyLys: 3.412 ± 0.625
4.987GlyLeu: 4.987 ± 0.541
2.1GlyMet: 2.1 ± 0.757
2.887GlyAsn: 2.887 ± 0.283
1.312GlyPro: 1.312 ± 0.478
1.05GlyGln: 1.05 ± 0.453
2.887GlyArg: 2.887 ± 1.379
6.037GlySer: 6.037 ± 0.689
4.199GlyThr: 4.199 ± 1.403
5.512GlyVal: 5.512 ± 1.133
0.787GlyTrp: 0.787 ± 0.464
1.05GlyTyr: 1.05 ± 0.411
0.0GlyXaa: 0.0 ± 0.0
His
0.262HisAla: 0.262 ± 0.323
1.05HisCys: 1.05 ± 0.498
1.837HisAsp: 1.837 ± 0.818
2.1HisGlu: 2.1 ± 0.765
1.312HisPhe: 1.312 ± 0.614
2.1HisGly: 2.1 ± 0.701
1.575HisHis: 1.575 ± 0.655
1.837HisIle: 1.837 ± 1.505
0.262HisLys: 0.262 ± 0.157
2.887HisLeu: 2.887 ± 0.565
1.312HisMet: 1.312 ± 0.509
1.312HisAsn: 1.312 ± 0.454
2.362HisPro: 2.362 ± 0.495
1.312HisGln: 1.312 ± 0.575
1.575HisArg: 1.575 ± 0.323
1.837HisSer: 1.837 ± 0.845
1.312HisThr: 1.312 ± 0.424
1.575HisVal: 1.575 ± 0.434
0.525HisTrp: 0.525 ± 0.314
0.262HisTyr: 0.262 ± 0.157
0.0HisXaa: 0.0 ± 0.0
Ile
3.412IleAla: 3.412 ± 0.773
1.05IleCys: 1.05 ± 0.497
2.887IleAsp: 2.887 ± 1.31
3.15IleGlu: 3.15 ± 0.564
1.837IlePhe: 1.837 ± 0.542
4.724IleGly: 4.724 ± 0.585
2.887IleHis: 2.887 ± 1.199
5.774IleIle: 5.774 ± 1.761
4.724IleLys: 4.724 ± 0.623
8.924IleLeu: 8.924 ± 1.185
2.625IleMet: 2.625 ± 0.695
4.462IleAsn: 4.462 ± 1.157
3.937IlePro: 3.937 ± 1.347
1.575IleGln: 1.575 ± 0.695
2.887IleArg: 2.887 ± 0.83
6.299IleSer: 6.299 ± 1.507
5.774IleThr: 5.774 ± 0.606
2.625IleVal: 2.625 ± 0.689
2.1IleTrp: 2.1 ± 0.469
2.1IleTyr: 2.1 ± 0.57
0.0IleXaa: 0.0 ± 0.0
Lys
4.724LysAla: 4.724 ± 1.271
0.262LysCys: 0.262 ± 0.157
2.1LysAsp: 2.1 ± 0.691
2.887LysGlu: 2.887 ± 1.148
0.525LysPhe: 0.525 ± 0.273
4.724LysGly: 4.724 ± 1.5
1.837LysHis: 1.837 ± 0.404
3.675LysIle: 3.675 ± 1.315
2.887LysLys: 2.887 ± 0.886
6.037LysLeu: 6.037 ± 1.315
1.837LysMet: 1.837 ± 0.658
2.625LysAsn: 2.625 ± 0.651
1.575LysPro: 1.575 ± 0.323
1.05LysGln: 1.05 ± 0.502
2.625LysArg: 2.625 ± 1.1
4.987LysSer: 4.987 ± 1.901
2.887LysThr: 2.887 ± 1.148
3.675LysVal: 3.675 ± 0.84
1.05LysTrp: 1.05 ± 0.621
1.837LysTyr: 1.837 ± 0.873
0.0LysXaa: 0.0 ± 0.0
Leu
7.349LeuAla: 7.349 ± 1.787
2.625LeuCys: 2.625 ± 0.632
6.037LeuAsp: 6.037 ± 2.142
4.462LeuGlu: 4.462 ± 0.541
3.412LeuPhe: 3.412 ± 0.621
6.037LeuGly: 6.037 ± 1.558
2.887LeuHis: 2.887 ± 0.702
8.399LeuIle: 8.399 ± 1.304
8.136LeuLys: 8.136 ± 0.86
9.711LeuLeu: 9.711 ± 1.324
2.1LeuMet: 2.1 ± 1.257
4.724LeuAsn: 4.724 ± 1.31
4.987LeuPro: 4.987 ± 1.483
3.937LeuGln: 3.937 ± 0.678
4.724LeuArg: 4.724 ± 1.272
9.186LeuSer: 9.186 ± 0.865
6.299LeuThr: 6.299 ± 0.967
5.512LeuVal: 5.512 ± 0.982
1.05LeuTrp: 1.05 ± 0.411
4.199LeuTyr: 4.199 ± 0.497
0.0LeuXaa: 0.0 ± 0.0
Met
0.787MetAla: 0.787 ± 0.471
0.525MetCys: 0.525 ± 0.273
1.575MetAsp: 1.575 ± 0.761
2.362MetGlu: 2.362 ± 0.332
0.787MetPhe: 0.787 ± 0.471
1.312MetGly: 1.312 ± 0.614
1.312MetHis: 1.312 ± 0.511
1.837MetIle: 1.837 ± 0.58
0.787MetLys: 0.787 ± 0.406
2.1MetLeu: 2.1 ± 0.758
1.05MetMet: 1.05 ± 0.497
0.787MetAsn: 0.787 ± 0.407
1.05MetPro: 1.05 ± 0.359
0.525MetGln: 0.525 ± 0.478
1.837MetArg: 1.837 ± 1.1
2.887MetSer: 2.887 ± 0.715
1.312MetThr: 1.312 ± 0.318
2.1MetVal: 2.1 ± 0.787
0.262MetTrp: 0.262 ± 0.157
0.262MetTyr: 0.262 ± 0.157
0.0MetXaa: 0.0 ± 0.0
Asn
1.05AsnAla: 1.05 ± 0.327
0.525AsnCys: 0.525 ± 0.413
1.837AsnAsp: 1.837 ± 0.697
1.312AsnGlu: 1.312 ± 0.581
1.312AsnPhe: 1.312 ± 0.419
0.787AsnGly: 0.787 ± 0.293
1.05AsnHis: 1.05 ± 0.554
3.937AsnIle: 3.937 ± 1.125
2.887AsnLys: 2.887 ± 0.812
4.987AsnLeu: 4.987 ± 1.149
1.312AsnMet: 1.312 ± 0.852
1.05AsnAsn: 1.05 ± 0.453
2.887AsnPro: 2.887 ± 0.585
1.575AsnGln: 1.575 ± 0.471
1.837AsnArg: 1.837 ± 0.845
2.625AsnSer: 2.625 ± 0.965
2.1AsnThr: 2.1 ± 0.971
2.887AsnVal: 2.887 ± 0.45
0.262AsnTrp: 0.262 ± 0.157
0.787AsnTyr: 0.787 ± 0.534
0.0AsnXaa: 0.0 ± 0.0
Pro
2.887ProAla: 2.887 ± 1.501
0.525ProCys: 0.525 ± 0.413
4.199ProAsp: 4.199 ± 0.673
3.15ProGlu: 3.15 ± 0.625
1.05ProPhe: 1.05 ± 0.404
2.1ProGly: 2.1 ± 0.823
1.312ProHis: 1.312 ± 0.424
4.462ProIle: 4.462 ± 1.278
1.05ProLys: 1.05 ± 0.372
4.987ProLeu: 4.987 ± 1.164
0.525ProMet: 0.525 ± 0.365
1.312ProAsn: 1.312 ± 0.318
2.1ProPro: 2.1 ± 1.508
1.837ProGln: 1.837 ± 0.61
1.05ProArg: 1.05 ± 0.502
5.249ProSer: 5.249 ± 0.767
3.937ProThr: 3.937 ± 0.803
3.937ProVal: 3.937 ± 0.97
0.787ProTrp: 0.787 ± 0.414
2.1ProTyr: 2.1 ± 0.677
0.0ProXaa: 0.0 ± 0.0
Gln
2.1GlnAla: 2.1 ± 0.65
0.525GlnCys: 0.525 ± 0.229
1.575GlnAsp: 1.575 ± 0.492
1.312GlnGlu: 1.312 ± 0.89
1.312GlnPhe: 1.312 ± 0.458
2.625GlnGly: 2.625 ± 1.441
0.262GlnHis: 0.262 ± 0.333
2.1GlnIle: 2.1 ± 1.032
1.312GlnLys: 1.312 ± 0.511
3.675GlnLeu: 3.675 ± 0.89
0.787GlnMet: 0.787 ± 0.471
0.787GlnAsn: 0.787 ± 0.293
0.262GlnPro: 0.262 ± 0.261
2.362GlnGln: 2.362 ± 1.464
1.837GlnArg: 1.837 ± 0.538
2.625GlnSer: 2.625 ± 0.625
1.837GlnThr: 1.837 ± 0.33
1.837GlnVal: 1.837 ± 0.41
0.0GlnTrp: 0.0 ± 0.0
1.312GlnTyr: 1.312 ± 0.786
0.0GlnXaa: 0.0 ± 0.0
Arg
2.362ArgAla: 2.362 ± 1.103
0.262ArgCys: 0.262 ± 0.157
2.362ArgAsp: 2.362 ± 1.414
3.937ArgGlu: 3.937 ± 1.554
1.575ArgPhe: 1.575 ± 0.505
3.937ArgGly: 3.937 ± 0.681
1.575ArgHis: 1.575 ± 0.465
5.249ArgIle: 5.249 ± 0.623
2.362ArgLys: 2.362 ± 0.404
3.412ArgLeu: 3.412 ± 0.637
0.787ArgMet: 0.787 ± 0.322
2.887ArgAsn: 2.887 ± 1.354
1.05ArgPro: 1.05 ± 0.524
2.1ArgGln: 2.1 ± 0.57
2.887ArgArg: 2.887 ± 0.585
4.199ArgSer: 4.199 ± 1.183
3.15ArgThr: 3.15 ± 0.758
2.362ArgVal: 2.362 ± 0.664
1.312ArgTrp: 1.312 ± 0.766
1.575ArgTyr: 1.575 ± 0.65
0.0ArgXaa: 0.0 ± 0.0
Ser
3.412SerAla: 3.412 ± 1.399
2.362SerCys: 2.362 ± 0.88
4.987SerAsp: 4.987 ± 1.57
3.937SerGlu: 3.937 ± 0.429
1.837SerPhe: 1.837 ± 0.538
6.562SerGly: 6.562 ± 1.453
2.625SerHis: 2.625 ± 0.453
4.199SerIle: 4.199 ± 0.966
4.724SerLys: 4.724 ± 1.07
11.286SerLeu: 11.286 ± 0.729
1.312SerMet: 1.312 ± 0.422
1.312SerAsn: 1.312 ± 0.454
4.724SerPro: 4.724 ± 1.322
2.1SerGln: 2.1 ± 0.758
4.987SerArg: 4.987 ± 1.162
9.711SerSer: 9.711 ± 1.832
5.774SerThr: 5.774 ± 0.818
7.349SerVal: 7.349 ± 1.623
2.362SerTrp: 2.362 ± 0.826
3.675SerTyr: 3.675 ± 0.429
0.262SerXaa: 0.262 ± 0.261
Thr
4.724ThrAla: 4.724 ± 1.666
0.787ThrCys: 0.787 ± 0.61
3.675ThrAsp: 3.675 ± 1.234
5.512ThrGlu: 5.512 ± 1.41
2.1ThrPhe: 2.1 ± 1.192
2.362ThrGly: 2.362 ± 0.371
1.05ThrHis: 1.05 ± 0.458
3.675ThrIle: 3.675 ± 0.691
2.362ThrLys: 2.362 ± 1.189
8.399ThrLeu: 8.399 ± 1.251
2.1ThrMet: 2.1 ± 0.998
1.575ThrAsn: 1.575 ± 0.734
3.412ThrPro: 3.412 ± 1.326
2.1ThrGln: 2.1 ± 0.317
2.362ThrArg: 2.362 ± 0.503
5.249ThrSer: 5.249 ± 1.068
3.937ThrThr: 3.937 ± 0.583
5.512ThrVal: 5.512 ± 0.924
1.837ThrTrp: 1.837 ± 0.589
2.625ThrTyr: 2.625 ± 1.709
0.0ThrXaa: 0.0 ± 0.0
Val
3.15ValAla: 3.15 ± 0.432
1.575ValCys: 1.575 ± 0.819
4.462ValAsp: 4.462 ± 0.857
3.412ValGlu: 3.412 ± 1.107
1.837ValPhe: 1.837 ± 0.589
4.199ValGly: 4.199 ± 1.176
2.625ValHis: 2.625 ± 0.959
4.462ValIle: 4.462 ± 1.618
4.199ValLys: 4.199 ± 0.18
4.724ValLeu: 4.724 ± 1.646
1.312ValMet: 1.312 ± 0.549
2.362ValAsn: 2.362 ± 0.703
5.249ValPro: 5.249 ± 0.749
1.05ValGln: 1.05 ± 0.387
2.362ValArg: 2.362 ± 0.565
5.774ValSer: 5.774 ± 1.089
4.987ValThr: 4.987 ± 0.971
3.15ValVal: 3.15 ± 1.255
0.787ValTrp: 0.787 ± 0.293
2.625ValTyr: 2.625 ± 0.297
0.0ValXaa: 0.0 ± 0.0
Trp
1.05TrpAla: 1.05 ± 0.387
0.262TrpCys: 0.262 ± 0.157
1.312TrpAsp: 1.312 ± 0.786
1.05TrpGlu: 1.05 ± 0.387
0.525TrpPhe: 0.525 ± 0.521
1.05TrpGly: 1.05 ± 0.359
0.262TrpHis: 0.262 ± 0.261
1.312TrpIle: 1.312 ± 0.952
1.05TrpLys: 1.05 ± 0.785
0.787TrpLeu: 0.787 ± 0.293
0.525TrpMet: 0.525 ± 0.521
0.525TrpAsn: 0.525 ± 0.314
0.262TrpPro: 0.262 ± 0.261
1.05TrpGln: 1.05 ± 1.038
1.837TrpArg: 1.837 ± 0.845
1.312TrpSer: 1.312 ± 0.359
1.837TrpThr: 1.837 ± 0.345
1.05TrpVal: 1.05 ± 0.629
0.787TrpTrp: 0.787 ± 0.782
0.787TrpTyr: 0.787 ± 0.464
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.837TyrAla: 1.837 ± 1.39
0.525TyrCys: 0.525 ± 0.229
2.362TyrAsp: 2.362 ± 0.71
1.575TyrGlu: 1.575 ± 0.528
1.312TyrPhe: 1.312 ± 0.502
2.625TyrGly: 2.625 ± 1.142
2.362TyrHis: 2.362 ± 1.181
2.625TyrIle: 2.625 ± 0.577
1.05TyrLys: 1.05 ± 0.281
3.675TyrLeu: 3.675 ± 0.946
0.525TyrMet: 0.525 ± 0.273
1.05TyrAsn: 1.05 ± 0.328
1.312TyrPro: 1.312 ± 0.502
1.837TyrGln: 1.837 ± 1.121
1.837TyrArg: 1.837 ± 0.866
2.362TyrSer: 2.362 ± 1.025
2.362TyrThr: 2.362 ± 0.961
1.05TyrVal: 1.05 ± 0.387
0.525TyrTrp: 0.525 ± 0.413
0.525TyrTyr: 0.525 ± 0.273
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.262XaaTrp: 0.262 ± 0.261
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3811 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski