Amino acid dipepetide frequency for Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.295AlaAla: 8.295 ± 0.062	1.107AlaCys: 1.107 ± 0.019	4.101AlaAsp: 4.101 ± 0.035	4.873AlaGlu: 4.873 ± 0.037	3.19AlaPhe: 3.19 ± 0.025	5.676AlaGly: 5.676 ± 0.042	1.753AlaHis: 1.753 ± 0.023	4.474AlaIle: 4.474 ± 0.033	3.786AlaLys: 3.786 ± 0.034	7.86AlaLeu: 7.86 ± 0.046	1.981AlaMet: 1.981 ± 0.026	2.903AlaAsn: 2.903 ± 0.028	4.426AlaPro: 4.426 ± 0.043	3.269AlaGln: 3.269 ± 0.032	4.633AlaArg: 4.633 ± 0.037	6.914AlaSer: 6.914 ± 0.049	5.131AlaThr: 5.131 ± 0.034	5.428AlaVal: 5.428 ± 0.04	1.2AlaTrp: 1.2 ± 0.018	2.283AlaTyr: 2.283 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.997CysAla: 0.997 ± 0.015	0.23CysCys: 0.23 ± 0.008	0.681CysAsp: 0.681 ± 0.014	0.609CysGlu: 0.609 ± 0.014	0.571CysPhe: 0.571 ± 0.012	0.935CysGly: 0.935 ± 0.017	0.333CysHis: 0.333 ± 0.01	0.738CysIle: 0.738 ± 0.014	0.484CysLys: 0.484 ± 0.01	1.345CysLeu: 1.345 ± 0.019	0.287CysMet: 0.287 ± 0.007	0.436CysAsn: 0.436 ± 0.011	0.655CysPro: 0.655 ± 0.016	0.469CysGln: 0.469 ± 0.011	0.745CysArg: 0.745 ± 0.012	0.946CysSer: 0.946 ± 0.018	0.721CysThr: 0.721 ± 0.015	0.85CysVal: 0.85 ± 0.018	0.206CysTrp: 0.206 ± 0.007	0.393CysTyr: 0.393 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.481AspAla: 4.481 ± 0.034	0.632AspCys: 0.632 ± 0.013	3.764AspAsp: 3.764 ± 0.035	4.159AspGlu: 4.159 ± 0.037	2.17AspPhe: 2.17 ± 0.021	3.965AspGly: 3.965 ± 0.037	1.295AspHis: 1.295 ± 0.016	3.253AspIle: 3.253 ± 0.031	2.326AspLys: 2.326 ± 0.027	5.141AspLeu: 5.141 ± 0.036	1.27AspMet: 1.27 ± 0.015	1.977AspAsn: 1.977 ± 0.022	3.342AspPro: 3.342 ± 0.03	1.943AspGln: 1.943 ± 0.023	3.044AspArg: 3.044 ± 0.03	4.109AspSer: 4.109 ± 0.029	3.032AspThr: 3.032 ± 0.027	3.696AspVal: 3.696 ± 0.03	0.905AspTrp: 0.905 ± 0.015	1.699AspTyr: 1.699 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.162GluAla: 5.162 ± 0.044	0.659GluCys: 0.659 ± 0.013	4.002GluAsp: 4.002 ± 0.038	5.282GluGlu: 5.282 ± 0.066	1.973GluPhe: 1.973 ± 0.023	3.699GluGly: 3.699 ± 0.034	1.39GluHis: 1.39 ± 0.017	3.091GluIle: 3.091 ± 0.032	3.702GluLys: 3.702 ± 0.041	5.219GluLeu: 5.219 ± 0.041	1.421GluMet: 1.421 ± 0.019	2.398GluAsn: 2.398 ± 0.026	2.728GluPro: 2.728 ± 0.035	2.487GluGln: 2.487 ± 0.027	3.776GluArg: 3.776 ± 0.035	4.382GluSer: 4.382 ± 0.038	3.543GluThr: 3.543 ± 0.032	3.583GluVal: 3.583 ± 0.033	0.906GluTrp: 0.906 ± 0.014	1.778GluTyr: 1.778 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.06PheAla: 3.06 ± 0.027	0.583PheCys: 0.583 ± 0.012	2.276PheAsp: 2.276 ± 0.025	2.109PheGlu: 2.109 ± 0.022	1.725PhePhe: 1.725 ± 0.02	2.928PheGly: 2.928 ± 0.032	0.965PheHis: 0.965 ± 0.015	1.972PheIle: 1.972 ± 0.026	1.472PheLys: 1.472 ± 0.019	3.727PheLeu: 3.727 ± 0.035	0.804PheMet: 0.804 ± 0.014	1.499PheAsn: 1.499 ± 0.019	2.043PhePro: 2.043 ± 0.022	1.453PheGln: 1.453 ± 0.017	2.007PheArg: 2.007 ± 0.021	3.069PheSer: 3.069 ± 0.027	2.253PheThr: 2.253 ± 0.022	2.485PheVal: 2.485 ± 0.029	0.673PheTrp: 0.673 ± 0.012	1.222PheTyr: 1.222 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.265GlyAla: 5.265 ± 0.041	0.912GlyCys: 0.912 ± 0.017	3.631GlyAsp: 3.631 ± 0.033	3.579GlyGlu: 3.579 ± 0.028	2.931GlyPhe: 2.931 ± 0.024	5.381GlyGly: 5.381 ± 0.059	1.703GlyHis: 1.703 ± 0.023	3.832GlyIle: 3.832 ± 0.033	3.345GlyLys: 3.345 ± 0.035	6.393GlyLeu: 6.393 ± 0.042	1.578GlyMet: 1.578 ± 0.023	2.612GlyAsn: 2.612 ± 0.027	3.281GlyPro: 3.281 ± 0.033	2.609GlyGln: 2.609 ± 0.026	3.925GlyArg: 3.925 ± 0.036	5.678GlySer: 5.678 ± 0.049	4.0GlyThr: 4.0 ± 0.037	4.634GlyVal: 4.634 ± 0.035	1.233GlyTrp: 1.233 ± 0.016	2.29GlyTyr: 2.29 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.82HisAla: 1.82 ± 0.023	0.335HisCys: 0.335 ± 0.008	1.337HisAsp: 1.337 ± 0.02	1.314HisGlu: 1.314 ± 0.018	0.942HisPhe: 0.942 ± 0.015	1.762HisGly: 1.762 ± 0.025	0.818HisHis: 0.818 ± 0.017	1.318HisIle: 1.318 ± 0.018	0.877HisLys: 0.877 ± 0.014	2.288HisLeu: 2.288 ± 0.029	0.502HisMet: 0.502 ± 0.011	0.871HisAsn: 0.871 ± 0.015	1.674HisPro: 1.674 ± 0.021	0.951HisGln: 0.951 ± 0.016	1.541HisArg: 1.541 ± 0.021	1.884HisSer: 1.884 ± 0.024	1.308HisThr: 1.308 ± 0.018	1.457HisVal: 1.457 ± 0.018	0.383HisTrp: 0.383 ± 0.01	0.745HisTyr: 0.745 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.412IleAla: 4.412 ± 0.035	0.801IleCys: 0.801 ± 0.015	2.922IleAsp: 2.922 ± 0.024	2.948IleGlu: 2.948 ± 0.026	2.147IlePhe: 2.147 ± 0.027	3.441IleGly: 3.441 ± 0.035	1.301IleHis: 1.301 ± 0.018	2.702IleIle: 2.702 ± 0.029	2.099IleLys: 2.099 ± 0.025	4.904IleLeu: 4.904 ± 0.037	1.053IleMet: 1.053 ± 0.017	1.886IleAsn: 1.886 ± 0.023	3.235IlePro: 3.235 ± 0.027	2.02IleGln: 2.02 ± 0.022	2.836IleArg: 2.836 ± 0.025	4.042IleSer: 4.042 ± 0.031	2.952IleThr: 2.952 ± 0.03	3.451IleVal: 3.451 ± 0.033	0.759IleTrp: 0.759 ± 0.013	1.586IleTyr: 1.586 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.026LysAla: 4.026 ± 0.036	0.509LysCys: 0.509 ± 0.014	2.771LysAsp: 2.771 ± 0.029	3.355LysGlu: 3.355 ± 0.039	1.431LysPhe: 1.431 ± 0.018	2.94LysGly: 2.94 ± 0.029	1.084LysHis: 1.084 ± 0.016	2.191LysIle: 2.191 ± 0.023	2.917LysLys: 2.917 ± 0.046	3.986LysLeu: 3.986 ± 0.035	0.914LysMet: 0.914 ± 0.015	1.734LysAsn: 1.734 ± 0.023	2.568LysPro: 2.568 ± 0.034	1.837LysGln: 1.837 ± 0.024	3.136LysArg: 3.136 ± 0.032	3.359LysSer: 3.359 ± 0.029	2.656LysThr: 2.656 ± 0.025	2.864LysVal: 2.864 ± 0.026	0.662LysTrp: 0.662 ± 0.011	1.425LysTyr: 1.425 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.796LeuAla: 7.796 ± 0.047	1.29LeuCys: 1.29 ± 0.017	5.203LeuAsp: 5.203 ± 0.03	5.615LeuGlu: 5.615 ± 0.043	3.508LeuPhe: 3.508 ± 0.033	6.237LeuGly: 6.237 ± 0.042	2.327LeuHis: 2.327 ± 0.026	4.278LeuIle: 4.278 ± 0.033	4.083LeuLys: 4.083 ± 0.035	8.741LeuLeu: 8.741 ± 0.067	1.89LeuMet: 1.89 ± 0.023	3.379LeuAsn: 3.379 ± 0.028	5.446LeuPro: 5.446 ± 0.035	3.912LeuGln: 3.912 ± 0.037	5.707LeuArg: 5.707 ± 0.043	7.599LeuSer: 7.599 ± 0.046	5.026LeuThr: 5.026 ± 0.036	5.711LeuVal: 5.711 ± 0.042	1.278LeuTrp: 1.278 ± 0.021	2.606LeuTyr: 2.606 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.125MetAla: 2.125 ± 0.023	0.277MetCys: 0.277 ± 0.008	1.216MetAsp: 1.216 ± 0.02	1.276MetGlu: 1.276 ± 0.018	0.768MetPhe: 0.768 ± 0.015	1.528MetGly: 1.528 ± 0.021	0.479MetHis: 0.479 ± 0.01	1.051MetIle: 1.051 ± 0.018	1.011MetLys: 1.011 ± 0.016	1.903MetLeu: 1.903 ± 0.023	0.562MetMet: 0.562 ± 0.013	0.832MetAsn: 0.832 ± 0.013	1.164MetPro: 1.164 ± 0.016	0.856MetGln: 0.856 ± 0.014	1.214MetArg: 1.214 ± 0.017	1.863MetSer: 1.863 ± 0.02	1.315MetThr: 1.315 ± 0.018	1.408MetVal: 1.408 ± 0.017	0.272MetTrp: 0.272 ± 0.009	0.561MetTyr: 0.561 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.159AsnAla: 3.159 ± 0.025	0.469AsnCys: 0.469 ± 0.011	1.996AsnAsp: 1.996 ± 0.024	2.088AsnGlu: 2.088 ± 0.024	1.397AsnPhe: 1.397 ± 0.018	3.02AsnGly: 3.02 ± 0.029	0.882AsnHis: 0.882 ± 0.013	2.197AsnIle: 2.197 ± 0.023	1.535AsnLys: 1.535 ± 0.021	3.349AsnLeu: 3.349 ± 0.028	0.878AsnMet: 0.878 ± 0.014	1.508AsnAsn: 1.508 ± 0.022	2.52AsnPro: 2.52 ± 0.026	1.349AsnGln: 1.349 ± 0.019	1.965AsnArg: 1.965 ± 0.018	2.748AsnSer: 2.748 ± 0.028	2.26AsnThr: 2.26 ± 0.024	2.427AsnVal: 2.427 ± 0.026	0.591AsnTrp: 0.591 ± 0.011	1.139AsnTyr: 1.139 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.721ProAla: 4.721 ± 0.051	0.537ProCys: 0.537 ± 0.013	3.215ProAsp: 3.215 ± 0.026	3.923ProGlu: 3.923 ± 0.036	2.119ProPhe: 2.119 ± 0.025	3.865ProGly: 3.865 ± 0.035	1.289ProHis: 1.289 ± 0.018	2.575ProIle: 2.575 ± 0.024	2.516ProLys: 2.516 ± 0.024	4.726ProLeu: 4.726 ± 0.04	1.046ProMet: 1.046 ± 0.019	2.192ProAsn: 2.192 ± 0.027	4.356ProPro: 4.356 ± 0.066	2.37ProGln: 2.37 ± 0.032	3.223ProArg: 3.223 ± 0.034	5.826ProSer: 5.826 ± 0.056	3.872ProThr: 3.872 ± 0.036	3.594ProVal: 3.594 ± 0.031	0.766ProTrp: 0.766 ± 0.013	1.598ProTyr: 1.598 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.32GlnAla: 3.32 ± 0.032	0.465GlnCys: 0.465 ± 0.011	2.065GlnAsp: 2.065 ± 0.023	2.462GlnGlu: 2.462 ± 0.03	1.332GlnPhe: 1.332 ± 0.017	2.523GlnGly: 2.523 ± 0.03	1.024GlnHis: 1.024 ± 0.018	1.955GlnIle: 1.955 ± 0.022	2.007GlnLys: 2.007 ± 0.02	3.53GlnLeu: 3.53 ± 0.029	0.89GlnMet: 0.89 ± 0.015	1.591GlnAsn: 1.591 ± 0.021	2.442GlnPro: 2.442 ± 0.036	2.2GlnGln: 2.2 ± 0.037	2.556GlnArg: 2.556 ± 0.026	3.174GlnSer: 3.174 ± 0.029	2.364GlnThr: 2.364 ± 0.025	2.237GlnVal: 2.237 ± 0.026	0.62GlnTrp: 0.62 ± 0.013	1.235GlnTyr: 1.235 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.434ArgAla: 4.434 ± 0.029	0.673ArgCys: 0.673 ± 0.013	3.265ArgAsp: 3.265 ± 0.033	3.692ArgGlu: 3.692 ± 0.041	2.204ArgPhe: 2.204 ± 0.023	3.558ArgGly: 3.558 ± 0.037	1.522ArgHis: 1.522 ± 0.019	2.91ArgIle: 2.91 ± 0.026	3.244ArgLys: 3.244 ± 0.032	5.539ArgLeu: 5.539 ± 0.042	1.27ArgMet: 1.27 ± 0.017	2.214ArgAsn: 2.214 ± 0.024	3.26ArgPro: 3.26 ± 0.033	2.549ArgGln: 2.549 ± 0.024	4.708ArgArg: 4.708 ± 0.048	4.575ArgSer: 4.575 ± 0.039	3.183ArgThr: 3.183 ± 0.027	3.392ArgVal: 3.392 ± 0.026	0.972ArgTrp: 0.972 ± 0.016	1.764ArgTyr: 1.764 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	6.465SerAla: 6.465 ± 0.05	0.904SerCys: 0.904 ± 0.017	4.268SerAsp: 4.268 ± 0.039	4.309SerGlu: 4.309 ± 0.036	3.163SerPhe: 3.163 ± 0.027	5.552SerGly: 5.552 ± 0.041	1.986SerHis: 1.986 ± 0.025	4.121SerIle: 4.121 ± 0.035	3.642SerLys: 3.642 ± 0.037	7.476SerLeu: 7.476 ± 0.045	1.705SerMet: 1.705 ± 0.019	3.049SerAsn: 3.049 ± 0.028	5.192SerPro: 5.192 ± 0.051	3.32SerGln: 3.32 ± 0.03	4.78SerArg: 4.78 ± 0.041	8.454SerSer: 8.454 ± 0.072	5.464SerThr: 5.464 ± 0.046	4.742SerVal: 4.742 ± 0.031	1.2SerTrp: 1.2 ± 0.017	2.2SerTyr: 2.2 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.102ThrAla: 5.102 ± 0.035	0.753ThrCys: 0.753 ± 0.014	2.974ThrAsp: 2.974 ± 0.025	3.24ThrGlu: 3.24 ± 0.031	2.309ThrPhe: 2.309 ± 0.024	4.299ThrGly: 4.299 ± 0.033	1.318ThrHis: 1.318 ± 0.017	3.211ThrIle: 3.211 ± 0.03	2.527ThrLys: 2.527 ± 0.023	5.363ThrLeu: 5.363 ± 0.037	1.216ThrMet: 1.216 ± 0.018	2.153ThrAsn: 2.153 ± 0.023	4.141ThrPro: 4.141 ± 0.042	2.121ThrGln: 2.121 ± 0.026	2.965ThrArg: 2.965 ± 0.028	5.216ThrSer: 5.216 ± 0.041	4.103ThrThr: 4.103 ± 0.042	3.972ThrVal: 3.972 ± 0.032	0.89ThrTrp: 0.89 ± 0.015	1.718ThrTyr: 1.718 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.218ValAla: 5.218 ± 0.041	0.868ValCys: 0.868 ± 0.013	3.865ValAsp: 3.865 ± 0.033	3.841ValGlu: 3.841 ± 0.03	2.596ValPhe: 2.596 ± 0.027	4.237ValGly: 4.237 ± 0.041	1.478ValHis: 1.478 ± 0.016	3.228ValIle: 3.228 ± 0.031	2.807ValLys: 2.807 ± 0.027	5.821ValLeu: 5.821 ± 0.038	1.358ValMet: 1.358 ± 0.018	2.367ValAsn: 2.367 ± 0.025	3.618ValPro: 3.618 ± 0.037	2.475ValGln: 2.475 ± 0.025	3.467ValArg: 3.467 ± 0.03	4.902ValSer: 4.902 ± 0.031	3.686ValThr: 3.686 ± 0.029	4.414ValVal: 4.414 ± 0.033	0.921ValTrp: 0.921 ± 0.016	1.905ValTyr: 1.905 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	1.148TrpAla: 1.148 ± 0.018	0.205TrpCys: 0.205 ± 0.008	0.933TrpAsp: 0.933 ± 0.015	0.878TrpGlu: 0.878 ± 0.014	0.568TrpPhe: 0.568 ± 0.012	1.005TrpGly: 1.005 ± 0.017	0.375TrpHis: 0.375 ± 0.009	0.813TrpIle: 0.813 ± 0.015	0.853TrpLys: 0.853 ± 0.014	1.455TrpLeu: 1.455 ± 0.02	0.389TrpMet: 0.389 ± 0.01	0.677TrpAsn: 0.677 ± 0.013	0.613TrpPro: 0.613 ± 0.011	0.59TrpGln: 0.59 ± 0.011	0.959TrpArg: 0.959 ± 0.015	1.081TrpSer: 1.081 ± 0.016	0.959TrpThr: 0.959 ± 0.015	0.961TrpVal: 0.961 ± 0.015	0.29TrpTrp: 0.29 ± 0.008	0.474TrpTyr: 0.474 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.279TyrAla: 2.279 ± 0.021	0.42TyrCys: 0.42 ± 0.011	1.718TyrAsp: 1.718 ± 0.021	1.628TyrGlu: 1.628 ± 0.023	1.28TyrPhe: 1.28 ± 0.019	2.262TyrGly: 2.262 ± 0.026	0.804TyrHis: 0.804 ± 0.016	1.587TyrIle: 1.587 ± 0.019	1.132TyrLys: 1.132 ± 0.018	2.865TyrLeu: 2.865 ± 0.027	0.668TyrMet: 0.668 ± 0.011	1.201TyrAsn: 1.201 ± 0.018	1.628TyrPro: 1.628 ± 0.02	1.212TyrGln: 1.212 ± 0.017	1.742TyrArg: 1.742 ± 0.02	2.172TyrSer: 2.172 ± 0.025	1.761TyrThr: 1.761 ± 0.023	1.766TyrVal: 1.766 ± 0.023	0.497TyrTrp: 0.497 ± 0.01	1.033TyrTyr: 1.033 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8651 proteins (4430027 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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