Amino acid dipepetide frequency for Atta colombica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.049AlaAla: 5.049 ± 0.049	1.234AlaCys: 1.234 ± 0.026	2.818AlaAsp: 2.818 ± 0.025	3.684AlaGlu: 3.684 ± 0.032	2.108AlaPhe: 2.108 ± 0.02	3.247AlaGly: 3.247 ± 0.027	1.384AlaHis: 1.384 ± 0.015	3.737AlaIle: 3.737 ± 0.025	3.531AlaLys: 3.531 ± 0.036	5.507AlaLeu: 5.507 ± 0.045	1.496AlaMet: 1.496 ± 0.017	2.738AlaAsn: 2.738 ± 0.022	2.581AlaPro: 2.581 ± 0.029	2.243AlaGln: 2.243 ± 0.025	3.61AlaArg: 3.61 ± 0.035	4.854AlaSer: 4.854 ± 0.031	3.953AlaThr: 3.953 ± 0.028	3.788AlaVal: 3.788 ± 0.03	0.606AlaTrp: 0.606 ± 0.01	1.622AlaTyr: 1.622 ± 0.017	0.001AlaXaa: 0.001 ± 0.001
Cys	1.153CysAla: 1.153 ± 0.016	0.519CysCys: 0.519 ± 0.011	1.145CysAsp: 1.145 ± 0.02	1.202CysGlu: 1.202 ± 0.024	0.765CysPhe: 0.765 ± 0.012	1.321CysGly: 1.321 ± 0.035	0.552CysHis: 0.552 ± 0.012	1.294CysIle: 1.294 ± 0.031	1.197CysLys: 1.197 ± 0.023	1.862CysLeu: 1.862 ± 0.027	0.444CysMet: 0.444 ± 0.008	1.066CysAsn: 1.066 ± 0.021	1.021CysPro: 1.021 ± 0.035	0.78CysGln: 0.78 ± 0.019	1.258CysArg: 1.258 ± 0.032	1.64CysSer: 1.64 ± 0.034	1.216CysThr: 1.216 ± 0.027	1.259CysVal: 1.259 ± 0.028	0.232CysTrp: 0.232 ± 0.006	0.621CysTyr: 0.621 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	2.97AspAla: 2.97 ± 0.029	1.01AspCys: 1.01 ± 0.024	3.772AspAsp: 3.772 ± 0.057	4.004AspGlu: 4.004 ± 0.032	2.033AspPhe: 2.033 ± 0.022	2.947AspGly: 2.947 ± 0.033	1.134AspHis: 1.134 ± 0.015	3.739AspIle: 3.739 ± 0.027	3.335AspLys: 3.335 ± 0.039	4.576AspLeu: 4.576 ± 0.032	1.221AspMet: 1.221 ± 0.017	2.826AspAsn: 2.826 ± 0.027	2.249AspPro: 2.249 ± 0.029	1.626AspGln: 1.626 ± 0.018	2.817AspArg: 2.817 ± 0.032	4.242AspSer: 4.242 ± 0.032	2.964AspThr: 2.964 ± 0.025	3.491AspVal: 3.491 ± 0.027	0.603AspTrp: 0.603 ± 0.01	1.775AspTyr: 1.775 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	3.72GluAla: 3.72 ± 0.033	1.226GluCys: 1.226 ± 0.039	3.976GluAsp: 3.976 ± 0.036	6.222GluGlu: 6.222 ± 0.08	2.068GluPhe: 2.068 ± 0.017	2.869GluGly: 2.869 ± 0.032	1.494GluHis: 1.494 ± 0.018	4.391GluIle: 4.391 ± 0.048	5.309GluLys: 5.309 ± 0.056	5.552GluLeu: 5.552 ± 0.045	1.598GluMet: 1.598 ± 0.019	3.949GluAsn: 3.949 ± 0.035	2.261GluPro: 2.261 ± 0.027	2.717GluGln: 2.717 ± 0.029	4.293GluArg: 4.293 ± 0.043	4.628GluSer: 4.628 ± 0.032	3.867GluThr: 3.867 ± 0.034	3.414GluVal: 3.414 ± 0.03	0.672GluTrp: 0.672 ± 0.012	1.962GluTyr: 1.962 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	2.156PheAla: 2.156 ± 0.018	0.845PheCys: 0.845 ± 0.013	1.999PheAsp: 1.999 ± 0.023	2.119PheGlu: 2.119 ± 0.022	1.611PhePhe: 1.611 ± 0.021	2.067PheGly: 2.067 ± 0.025	1.021PheHis: 1.021 ± 0.013	2.27PheIle: 2.27 ± 0.024	1.99PheLys: 1.99 ± 0.018	3.696PheLeu: 3.696 ± 0.035	0.812PheMet: 0.812 ± 0.012	1.778PheAsn: 1.778 ± 0.021	1.684PhePro: 1.684 ± 0.019	1.38PheGln: 1.38 ± 0.016	1.93PheArg: 1.93 ± 0.021	2.949PheSer: 2.949 ± 0.023	2.128PheThr: 2.128 ± 0.023	2.371PheVal: 2.371 ± 0.022	0.425PheTrp: 0.425 ± 0.008	1.354PheTyr: 1.354 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	2.978GlyAla: 2.978 ± 0.03	1.037GlyCys: 1.037 ± 0.02	2.688GlyAsp: 2.688 ± 0.033	3.025GlyGlu: 3.025 ± 0.031	1.997GlyPhe: 1.997 ± 0.024	4.126GlyGly: 4.126 ± 0.058	1.352GlyHis: 1.352 ± 0.019	3.302GlyIle: 3.302 ± 0.027	3.252GlyLys: 3.252 ± 0.031	4.244GlyLeu: 4.244 ± 0.04	1.201GlyMet: 1.201 ± 0.017	2.664GlyAsn: 2.664 ± 0.026	2.23GlyPro: 2.23 ± 0.039	1.898GlyGln: 1.898 ± 0.022	3.178GlyArg: 3.178 ± 0.026	4.383GlySer: 4.383 ± 0.038	3.142GlyThr: 3.142 ± 0.032	3.015GlyVal: 3.015 ± 0.028	0.646GlyTrp: 0.646 ± 0.012	1.876GlyTyr: 1.876 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.421HisAla: 1.421 ± 0.016	0.614HisCys: 0.614 ± 0.012	1.175HisAsp: 1.175 ± 0.015	1.436HisGlu: 1.436 ± 0.02	0.982HisPhe: 0.982 ± 0.013	1.386HisGly: 1.386 ± 0.018	1.162HisHis: 1.162 ± 0.035	1.529HisIle: 1.529 ± 0.017	1.36HisLys: 1.36 ± 0.017	2.357HisLeu: 2.357 ± 0.025	0.606HisMet: 0.606 ± 0.012	1.198HisAsn: 1.198 ± 0.015	1.382HisPro: 1.382 ± 0.017	1.105HisGln: 1.105 ± 0.017	1.624HisArg: 1.624 ± 0.019	2.023HisSer: 2.023 ± 0.023	1.427HisThr: 1.427 ± 0.02	1.584HisVal: 1.584 ± 0.017	0.284HisTrp: 0.284 ± 0.007	0.879HisTyr: 0.879 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.932IleAla: 3.932 ± 0.028	1.4IleCys: 1.4 ± 0.025	3.454IleAsp: 3.454 ± 0.03	4.02IleGlu: 4.02 ± 0.046	2.567IlePhe: 2.567 ± 0.028	3.091IleGly: 3.091 ± 0.025	1.49IleHis: 1.49 ± 0.019	4.123IleIle: 4.123 ± 0.045	3.944IleLys: 3.944 ± 0.04	5.938IleLeu: 5.938 ± 0.049	1.421IleMet: 1.421 ± 0.017	3.316IleAsn: 3.316 ± 0.033	3.024IlePro: 3.024 ± 0.028	2.414IleGln: 2.414 ± 0.022	3.182IleArg: 3.182 ± 0.022	5.117IleSer: 5.117 ± 0.035	3.701IleThr: 3.701 ± 0.029	3.888IleVal: 3.888 ± 0.027	0.624IleTrp: 0.624 ± 0.011	2.075IleTyr: 2.075 ± 0.023	0.001IleXaa: 0.001 ± 0.0
Lys	3.174LysAla: 3.174 ± 0.029	1.254LysCys: 1.254 ± 0.025	3.533LysAsp: 3.533 ± 0.043	4.971LysGlu: 4.971 ± 0.057	2.155LysPhe: 2.155 ± 0.021	2.537LysGly: 2.537 ± 0.025	1.545LysHis: 1.545 ± 0.019	4.321LysIle: 4.321 ± 0.039	5.486LysLys: 5.486 ± 0.065	5.701LysLeu: 5.701 ± 0.043	1.552LysMet: 1.552 ± 0.017	3.536LysAsn: 3.536 ± 0.035	2.663LysPro: 2.663 ± 0.039	2.681LysGln: 2.681 ± 0.024	4.074LysArg: 4.074 ± 0.036	4.805LysSer: 4.805 ± 0.044	3.619LysThr: 3.619 ± 0.034	3.268LysVal: 3.268 ± 0.027	0.671LysTrp: 0.671 ± 0.011	2.2LysTyr: 2.2 ± 0.026	0.001LysXaa: 0.001 ± 0.0
Leu	5.679LeuAla: 5.679 ± 0.045	1.87LeuCys: 1.87 ± 0.024	4.602LeuAsp: 4.602 ± 0.034	5.888LeuGlu: 5.888 ± 0.049	3.281LeuPhe: 3.281 ± 0.033	4.201LeuGly: 4.201 ± 0.034	2.539LeuHis: 2.539 ± 0.023	5.099LeuIle: 5.099 ± 0.042	5.849LeuLys: 5.849 ± 0.044	8.894LeuLeu: 8.894 ± 0.076	2.072LeuMet: 2.072 ± 0.022	4.325LeuAsn: 4.325 ± 0.032	4.763LeuPro: 4.763 ± 0.033	4.395LeuGln: 4.395 ± 0.038	5.521LeuArg: 5.521 ± 0.032	7.422LeuSer: 7.422 ± 0.044	5.104LeuThr: 5.104 ± 0.035	4.777LeuVal: 4.777 ± 0.035	0.931LeuTrp: 0.931 ± 0.015	2.866LeuTyr: 2.866 ± 0.025	0.001LeuXaa: 0.001 ± 0.0
Met	1.49MetAla: 1.49 ± 0.017	0.449MetCys: 0.449 ± 0.009	1.287MetAsp: 1.287 ± 0.018	1.666MetGlu: 1.666 ± 0.018	0.845MetPhe: 0.845 ± 0.014	1.071MetGly: 1.071 ± 0.016	0.579MetHis: 0.579 ± 0.01	1.404MetIle: 1.404 ± 0.018	1.608MetLys: 1.608 ± 0.016	2.104MetLeu: 2.104 ± 0.022	0.66MetMet: 0.66 ± 0.013	1.158MetAsn: 1.158 ± 0.016	1.139MetPro: 1.139 ± 0.016	1.118MetGln: 1.118 ± 0.014	1.367MetArg: 1.367 ± 0.016	1.848MetSer: 1.848 ± 0.015	1.371MetThr: 1.371 ± 0.015	1.186MetVal: 1.186 ± 0.014	0.242MetTrp: 0.242 ± 0.006	0.743MetTyr: 0.743 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.974AsnAla: 2.974 ± 0.028	0.989AsnCys: 0.989 ± 0.017	2.86AsnAsp: 2.86 ± 0.03	3.4AsnGlu: 3.4 ± 0.033	1.941AsnPhe: 1.941 ± 0.023	2.83AsnGly: 2.83 ± 0.027	1.194AsnHis: 1.194 ± 0.018	3.763AsnIle: 3.763 ± 0.034	3.261AsnLys: 3.261 ± 0.028	4.584AsnLeu: 4.584 ± 0.032	1.245AsnMet: 1.245 ± 0.017	3.419AsnAsn: 3.419 ± 0.035	2.234AsnPro: 2.234 ± 0.028	1.928AsnGln: 1.928 ± 0.019	2.573AsnArg: 2.573 ± 0.021	4.136AsnSer: 4.136 ± 0.034	2.965AsnThr: 2.965 ± 0.022	3.45AsnVal: 3.45 ± 0.026	0.524AsnTrp: 0.524 ± 0.01	1.729AsnTyr: 1.729 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	2.872ProAla: 2.872 ± 0.029	0.862ProCys: 0.862 ± 0.043	2.312ProAsp: 2.312 ± 0.022	2.975ProGlu: 2.975 ± 0.039	1.669ProPhe: 1.669 ± 0.021	2.727ProGly: 2.727 ± 0.063	1.199ProHis: 1.199 ± 0.017	2.808ProIle: 2.808 ± 0.025	2.52ProLys: 2.52 ± 0.028	4.143ProLeu: 4.143 ± 0.031	1.005ProMet: 1.005 ± 0.014	2.198ProAsn: 2.198 ± 0.021	4.09ProPro: 4.09 ± 0.068	1.966ProGln: 1.966 ± 0.028	2.808ProArg: 2.808 ± 0.029	4.357ProSer: 4.357 ± 0.046	3.07ProThr: 3.07 ± 0.025	2.942ProVal: 2.942 ± 0.029	0.497ProTrp: 0.497 ± 0.011	1.48ProTyr: 1.48 ± 0.02	0.001ProXaa: 0.001 ± 0.0
Gln	2.297GlnAla: 2.297 ± 0.024	0.819GlnCys: 0.819 ± 0.022	1.922GlnAsp: 1.922 ± 0.018	2.87GlnGlu: 2.87 ± 0.027	1.356GlnPhe: 1.356 ± 0.014	1.734GlnGly: 1.734 ± 0.023	1.225GlnHis: 1.225 ± 0.017	2.428GlnIle: 2.428 ± 0.025	2.571GlnLys: 2.571 ± 0.025	3.804GlnLeu: 3.804 ± 0.037	0.997GlnMet: 0.997 ± 0.016	2.254GlnAsn: 2.254 ± 0.021	1.954GlnPro: 1.954 ± 0.026	3.481GlnGln: 3.481 ± 0.087	2.589GlnArg: 2.589 ± 0.026	3.163GlnSer: 3.163 ± 0.03	2.304GlnThr: 2.304 ± 0.024	2.136GlnVal: 2.136 ± 0.021	0.461GlnTrp: 0.461 ± 0.009	1.299GlnTyr: 1.299 ± 0.016	0.001GlnXaa: 0.001 ± 0.0
Arg	3.332ArgAla: 3.332 ± 0.03	1.257ArgCys: 1.257 ± 0.023	3.143ArgAsp: 3.143 ± 0.029	4.086ArgGlu: 4.086 ± 0.035	2.079ArgPhe: 2.079 ± 0.02	3.144ArgGly: 3.144 ± 0.03	1.673ArgHis: 1.673 ± 0.019	3.442ArgIle: 3.442 ± 0.028	4.128ArgLys: 4.128 ± 0.035	5.182ArgLeu: 5.182 ± 0.039	1.349ArgMet: 1.349 ± 0.014	3.097ArgAsn: 3.097 ± 0.023	2.626ArgPro: 2.626 ± 0.031	2.441ArgGln: 2.441 ± 0.023	4.879ArgArg: 4.879 ± 0.047	4.744ArgSer: 4.744 ± 0.048	3.136ArgThr: 3.136 ± 0.026	3.144ArgVal: 3.144 ± 0.027	0.663ArgTrp: 0.663 ± 0.011	1.924ArgTyr: 1.924 ± 0.021	0.001ArgXaa: 0.001 ± 0.0
Ser	4.619SerAla: 4.619 ± 0.033	1.602SerCys: 1.602 ± 0.03	4.274SerAsp: 4.274 ± 0.035	4.77SerGlu: 4.77 ± 0.034	2.921SerPhe: 2.921 ± 0.024	4.573SerGly: 4.573 ± 0.039	1.968SerHis: 1.968 ± 0.021	4.768SerIle: 4.768 ± 0.03	4.722SerLys: 4.722 ± 0.035	7.3SerLeu: 7.3 ± 0.042	1.827SerMet: 1.827 ± 0.02	4.315SerAsn: 4.315 ± 0.033	4.515SerPro: 4.515 ± 0.05	3.219SerGln: 3.219 ± 0.027	4.897SerArg: 4.897 ± 0.046	8.847SerSer: 8.847 ± 0.079	5.471SerThr: 5.471 ± 0.044	4.71SerVal: 4.71 ± 0.027	0.839SerTrp: 0.839 ± 0.012	2.337SerTyr: 2.337 ± 0.022	0.001SerXaa: 0.001 ± 0.0
Thr	3.775ThrAla: 3.775 ± 0.027	1.262ThrCys: 1.262 ± 0.028	2.966ThrAsp: 2.966 ± 0.023	3.663ThrGlu: 3.663 ± 0.036	2.192ThrPhe: 2.192 ± 0.022	3.207ThrGly: 3.207 ± 0.029	1.341ThrHis: 1.341 ± 0.018	3.815ThrIle: 3.815 ± 0.032	3.514ThrLys: 3.514 ± 0.034	5.364ThrLeu: 5.364 ± 0.032	1.441ThrMet: 1.441 ± 0.016	3.019ThrAsn: 3.019 ± 0.023	3.188ThrPro: 3.188 ± 0.039	2.161ThrGln: 2.161 ± 0.021	3.18ThrArg: 3.18 ± 0.025	5.429ThrSer: 5.429 ± 0.039	4.551ThrThr: 4.551 ± 0.063	3.801ThrVal: 3.801 ± 0.029	0.642ThrTrp: 0.642 ± 0.01	1.784ThrTyr: 1.784 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	3.918ValAla: 3.918 ± 0.027	1.331ValCys: 1.331 ± 0.027	3.091ValAsp: 3.091 ± 0.024	3.655ValGlu: 3.655 ± 0.029	2.183ValPhe: 2.183 ± 0.021	2.905ValGly: 2.905 ± 0.024	1.493ValHis: 1.493 ± 0.015	3.706ValIle: 3.706 ± 0.031	3.521ValLys: 3.521 ± 0.032	5.211ValLeu: 5.211 ± 0.038	1.336ValMet: 1.336 ± 0.016	2.832ValAsn: 2.832 ± 0.024	3.011ValPro: 3.011 ± 0.029	2.395ValGln: 2.395 ± 0.021	3.11ValArg: 3.11 ± 0.024	4.693ValSer: 4.693 ± 0.031	3.881ValThr: 3.881 ± 0.034	3.675ValVal: 3.675 ± 0.035	0.621ValTrp: 0.621 ± 0.012	1.81ValTyr: 1.81 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	0.527TrpAla: 0.527 ± 0.01	0.232TrpCys: 0.232 ± 0.006	0.568TrpAsp: 0.568 ± 0.011	0.611TrpGlu: 0.611 ± 0.009	0.425TrpPhe: 0.425 ± 0.009	0.515TrpGly: 0.515 ± 0.011	0.292TrpHis: 0.292 ± 0.007	0.726TrpIle: 0.726 ± 0.012	0.74TrpLys: 0.74 ± 0.014	1.104TrpLeu: 1.104 ± 0.016	0.288TrpMet: 0.288 ± 0.007	0.592TrpAsn: 0.592 ± 0.011	0.419TrpPro: 0.419 ± 0.011	0.47TrpGln: 0.47 ± 0.009	0.735TrpArg: 0.735 ± 0.011	0.824TrpSer: 0.824 ± 0.011	0.61TrpThr: 0.61 ± 0.01	0.495TrpVal: 0.495 ± 0.009	0.183TrpTrp: 0.183 ± 0.006	0.372TrpTyr: 0.372 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.755TyrAla: 1.755 ± 0.017	0.737TyrCys: 0.737 ± 0.013	1.75TyrAsp: 1.75 ± 0.018	1.923TyrGlu: 1.923 ± 0.018	1.406TyrPhe: 1.406 ± 0.018	1.737TyrGly: 1.737 ± 0.019	0.896TyrHis: 0.896 ± 0.012	2.056TyrIle: 2.056 ± 0.021	1.909TyrLys: 1.909 ± 0.019	2.954TyrLeu: 2.954 ± 0.027	0.766TyrMet: 0.766 ± 0.011	1.717TyrAsn: 1.717 ± 0.019	1.468TyrPro: 1.468 ± 0.022	1.248TyrGln: 1.248 ± 0.015	1.841TyrArg: 1.841 ± 0.018	2.389TyrSer: 2.389 ± 0.02	1.813TyrThr: 1.813 ± 0.019	1.985TyrVal: 1.985 ± 0.022	0.362TyrTrp: 0.362 ± 0.008	1.266TyrTyr: 1.266 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.002XaaTyr: 0.002 ± 0.001	0.396XaaXaa: 0.396 ± 0.059

Statistics based on 14143 proteins (6716947 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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