Amino acid dipepetide frequency for Spring viremia of carp virus (Rhabdovirus carpia)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.659AlaAla: 3.659 ± 0.613
1.407AlaCys: 1.407 ± 0.567
2.533AlaAsp: 2.533 ± 0.798
2.252AlaGlu: 2.252 ± 0.936
0.844AlaPhe: 0.844 ± 0.637
2.252AlaGly: 2.252 ± 0.517
1.126AlaHis: 1.126 ± 0.502
2.815AlaIle: 2.815 ± 1.167
1.97AlaLys: 1.97 ± 0.723
5.629AlaLeu: 5.629 ± 0.941
0.563AlaMet: 0.563 ± 0.311
0.844AlaAsn: 0.844 ± 0.309
0.844AlaPro: 0.844 ± 0.619
1.126AlaGln: 1.126 ± 0.622
1.689AlaArg: 1.689 ± 0.295
3.377AlaSer: 3.377 ± 1.395
3.94AlaThr: 3.94 ± 1.429
2.533AlaVal: 2.533 ± 0.547
0.844AlaTrp: 0.844 ± 0.776
1.97AlaTyr: 1.97 ± 1.198
0.0AlaXaa: 0.0 ± 0.0
Cys
0.844CysAla: 0.844 ± 0.822
0.281CysCys: 0.281 ± 0.357
0.844CysAsp: 0.844 ± 0.619
1.126CysGlu: 1.126 ± 0.591
0.281CysPhe: 0.281 ± 0.155
1.407CysGly: 1.407 ± 0.341
0.563CysHis: 0.563 ± 0.295
1.126CysIle: 1.126 ± 0.622
1.407CysLys: 1.407 ± 0.874
1.407CysLeu: 1.407 ± 0.777
0.0CysMet: 0.0 ± 0.0
1.126CysAsn: 1.126 ± 0.333
1.126CysPro: 1.126 ± 0.39
1.97CysGln: 1.97 ± 0.641
1.407CysArg: 1.407 ± 0.588
0.563CysSer: 0.563 ± 0.454
0.844CysThr: 0.844 ± 0.309
1.407CysVal: 1.407 ± 0.588
0.281CysTrp: 0.281 ± 0.155
0.281CysTyr: 0.281 ± 0.506
0.0CysXaa: 0.0 ± 0.0
Asp
1.126AspAla: 1.126 ± 0.317
0.281AspCys: 0.281 ± 0.434
3.659AspAsp: 3.659 ± 1.854
4.222AspGlu: 4.222 ± 1.865
1.126AspPhe: 1.126 ± 0.485
3.377AspGly: 3.377 ± 1.534
0.844AspHis: 0.844 ± 0.309
4.222AspIle: 4.222 ± 0.963
2.252AspLys: 2.252 ± 0.651
5.91AspLeu: 5.91 ± 1.422
1.97AspMet: 1.97 ± 1.285
2.533AspAsn: 2.533 ± 0.988
2.533AspPro: 2.533 ± 0.759
1.97AspGln: 1.97 ± 0.609
2.252AspArg: 2.252 ± 0.928
5.348AspSer: 5.348 ± 1.02
3.377AspThr: 3.377 ± 1.235
3.94AspVal: 3.94 ± 1.399
3.096AspTrp: 3.096 ± 0.564
2.815AspTyr: 2.815 ± 0.732
0.0AspXaa: 0.0 ± 0.0
Glu
2.815GluAla: 2.815 ± 0.627
1.97GluCys: 1.97 ± 1.077
5.066GluAsp: 5.066 ± 2.391
8.444GluGlu: 8.444 ± 3.683
1.97GluPhe: 1.97 ± 0.522
4.503GluGly: 4.503 ± 0.847
2.252GluHis: 2.252 ± 1.0
3.94GluIle: 3.94 ± 0.677
4.785GluLys: 4.785 ± 0.59
5.066GluLeu: 5.066 ± 0.881
2.252GluMet: 2.252 ± 0.531
2.252GluAsn: 2.252 ± 0.529
2.533GluPro: 2.533 ± 1.537
1.126GluGln: 1.126 ± 0.526
2.533GluArg: 2.533 ± 0.421
5.629GluSer: 5.629 ± 1.417
3.94GluThr: 3.94 ± 1.06
4.785GluVal: 4.785 ± 0.942
1.97GluTrp: 1.97 ± 0.827
1.689GluTyr: 1.689 ± 0.64
0.0GluXaa: 0.0 ± 0.0
Phe
0.844PheAla: 0.844 ± 0.309
0.844PheCys: 0.844 ± 0.309
1.689PheAsp: 1.689 ± 1.024
2.815PheGlu: 2.815 ± 0.948
1.689PhePhe: 1.689 ± 0.5
3.377PheGly: 3.377 ± 1.105
0.281PheHis: 0.281 ± 0.434
1.407PheIle: 1.407 ± 0.341
1.97PheLys: 1.97 ± 0.633
3.94PheLeu: 3.94 ± 0.666
0.844PheMet: 0.844 ± 0.453
1.689PheAsn: 1.689 ± 0.919
2.533PhePro: 2.533 ± 0.544
1.689PheGln: 1.689 ± 0.576
3.096PheArg: 3.096 ± 0.657
2.533PheSer: 2.533 ± 0.656
1.407PheThr: 1.407 ± 0.475
1.126PheVal: 1.126 ± 0.39
0.844PheTrp: 0.844 ± 0.424
0.844PheTyr: 0.844 ± 0.553
0.0PheXaa: 0.0 ± 0.0
Gly
1.689GlyAla: 1.689 ± 0.933
0.281GlyCys: 0.281 ± 0.155
4.785GlyAsp: 4.785 ± 0.706
3.096GlyGlu: 3.096 ± 1.027
2.815GlyPhe: 2.815 ± 0.751
3.94GlyGly: 3.94 ± 0.837
2.252GlyHis: 2.252 ± 0.634
5.629GlyIle: 5.629 ± 0.761
4.785GlyLys: 4.785 ± 0.747
9.288GlyLeu: 9.288 ± 1.198
1.407GlyMet: 1.407 ± 0.492
3.94GlyAsn: 3.94 ± 1.542
2.533GlyPro: 2.533 ± 0.676
2.533GlyGln: 2.533 ± 0.653
3.096GlyArg: 3.096 ± 0.671
4.222GlySer: 4.222 ± 1.473
5.348GlyThr: 5.348 ± 2.283
2.815GlyVal: 2.815 ± 0.933
1.689GlyTrp: 1.689 ± 0.886
1.407GlyTyr: 1.407 ± 0.463
0.0GlyXaa: 0.0 ± 0.0
His
1.126HisAla: 1.126 ± 0.591
0.563HisCys: 0.563 ± 0.379
0.844HisAsp: 0.844 ± 0.619
1.407HisGlu: 1.407 ± 0.968
1.689HisPhe: 1.689 ± 0.692
1.126HisGly: 1.126 ± 0.563
1.126HisHis: 1.126 ± 0.39
1.97HisIle: 1.97 ± 0.686
1.97HisLys: 1.97 ± 0.777
1.689HisLeu: 1.689 ± 0.413
0.0HisMet: 0.0 ± 0.0
1.126HisAsn: 1.126 ± 0.622
2.533HisPro: 2.533 ± 0.805
0.844HisGln: 0.844 ± 0.453
1.689HisArg: 1.689 ± 0.777
2.815HisSer: 2.815 ± 1.371
0.563HisThr: 0.563 ± 0.311
2.815HisVal: 2.815 ± 0.844
0.563HisTrp: 0.563 ± 0.295
1.97HisTyr: 1.97 ± 0.782
0.0HisXaa: 0.0 ± 0.0
Ile
1.97IleAla: 1.97 ± 0.451
1.689IleCys: 1.689 ± 0.576
5.066IleAsp: 5.066 ± 1.908
3.94IleGlu: 3.94 ± 0.577
1.689IlePhe: 1.689 ± 0.886
5.348IleGly: 5.348 ± 1.247
1.97IleHis: 1.97 ± 1.218
3.94IleIle: 3.94 ± 1.499
5.066IleLys: 5.066 ± 1.893
3.659IleLeu: 3.659 ± 1.38
1.97IleMet: 1.97 ± 0.641
2.533IleAsn: 2.533 ± 1.077
4.785IlePro: 4.785 ± 0.961
2.815IleGln: 2.815 ± 0.594
5.629IleArg: 5.629 ± 0.716
5.91IleSer: 5.91 ± 0.749
2.533IleThr: 2.533 ± 0.335
3.096IleVal: 3.096 ± 0.809
0.844IleTrp: 0.844 ± 0.309
1.97IleTyr: 1.97 ± 0.782
0.0IleXaa: 0.0 ± 0.0
Lys
2.815LysAla: 2.815 ± 0.852
0.844LysCys: 0.844 ± 0.309
2.533LysAsp: 2.533 ± 0.335
5.629LysGlu: 5.629 ± 2.196
2.252LysPhe: 2.252 ± 0.886
4.222LysGly: 4.222 ± 0.97
1.407LysHis: 1.407 ± 0.548
3.94LysIle: 3.94 ± 1.805
2.252LysLys: 2.252 ± 0.739
7.318LysLeu: 7.318 ± 0.951
2.252LysMet: 2.252 ± 0.706
2.533LysAsn: 2.533 ± 0.653
2.252LysPro: 2.252 ± 1.445
1.97LysGln: 1.97 ± 0.723
4.785LysArg: 4.785 ± 0.714
4.222LysSer: 4.222 ± 1.021
5.066LysThr: 5.066 ± 0.751
3.659LysVal: 3.659 ± 0.825
1.126LysTrp: 1.126 ± 0.379
1.97LysTyr: 1.97 ± 1.254
0.0LysXaa: 0.0 ± 0.0
Leu
4.222LeuAla: 4.222 ± 1.206
1.407LeuCys: 1.407 ± 0.264
5.066LeuAsp: 5.066 ± 1.103
5.91LeuGlu: 5.91 ± 1.217
2.815LeuPhe: 2.815 ± 0.888
5.348LeuGly: 5.348 ± 0.484
1.97LeuHis: 1.97 ± 0.882
7.881LeuIle: 7.881 ± 0.728
6.755LeuLys: 6.755 ± 1.356
8.162LeuLeu: 8.162 ± 1.264
3.096LeuMet: 3.096 ± 0.922
5.066LeuAsn: 5.066 ± 0.881
3.096LeuPro: 3.096 ± 1.192
2.815LeuGln: 2.815 ± 0.532
6.755LeuArg: 6.755 ± 2.051
8.444LeuSer: 8.444 ± 2.962
5.91LeuThr: 5.91 ± 1.519
4.785LeuVal: 4.785 ± 1.524
0.844LeuTrp: 0.844 ± 0.407
3.659LeuTyr: 3.659 ± 1.108
0.0LeuXaa: 0.0 ± 0.0
Met
1.97MetAla: 1.97 ± 0.777
0.0MetCys: 0.0 ± 0.0
1.126MetAsp: 1.126 ± 0.502
1.97MetGlu: 1.97 ± 0.835
1.689MetPhe: 1.689 ± 0.432
2.252MetGly: 2.252 ± 0.606
0.563MetHis: 0.563 ± 0.311
1.126MetIle: 1.126 ± 0.39
2.252MetLys: 2.252 ± 0.8
2.252MetLeu: 2.252 ± 0.873
1.407MetMet: 1.407 ± 0.874
0.844MetAsn: 0.844 ± 0.407
1.126MetPro: 1.126 ± 1.169
0.563MetGln: 0.563 ± 0.311
2.252MetArg: 2.252 ± 0.467
3.659MetSer: 3.659 ± 1.205
1.689MetThr: 1.689 ± 0.64
0.844MetVal: 0.844 ± 0.453
0.0MetTrp: 0.0 ± 0.0
1.126MetTyr: 1.126 ± 0.591
0.0MetXaa: 0.0 ± 0.0
Asn
2.815AsnAla: 2.815 ± 1.78
1.689AsnCys: 1.689 ± 0.539
0.844AsnAsp: 0.844 ± 0.332
1.407AsnGlu: 1.407 ± 0.51
0.844AsnPhe: 0.844 ± 0.309
4.503AsnGly: 4.503 ± 1.589
2.252AsnHis: 2.252 ± 0.755
1.407AsnIle: 1.407 ± 0.584
3.94AsnLys: 3.94 ± 1.325
5.348AsnLeu: 5.348 ± 0.883
0.844AsnMet: 0.844 ± 0.309
2.815AsnAsn: 2.815 ± 1.227
1.97AsnPro: 1.97 ± 0.391
1.126AsnGln: 1.126 ± 0.622
0.563AsnArg: 0.563 ± 0.311
3.377AsnSer: 3.377 ± 1.194
2.252AsnThr: 2.252 ± 0.886
1.407AsnVal: 1.407 ± 0.926
0.844AsnTrp: 0.844 ± 0.453
1.689AsnTyr: 1.689 ± 0.295
0.0AsnXaa: 0.0 ± 0.0
Pro
1.97ProAla: 1.97 ± 0.391
0.281ProCys: 0.281 ± 0.155
4.503ProAsp: 4.503 ± 1.544
0.563ProGlu: 0.563 ± 0.379
1.97ProPhe: 1.97 ± 0.402
1.126ProGly: 1.126 ± 0.586
2.252ProHis: 2.252 ± 0.981
3.377ProIle: 3.377 ± 1.235
1.97ProLys: 1.97 ± 0.723
4.222ProLeu: 4.222 ± 0.851
0.844ProMet: 0.844 ± 0.52
1.689ProAsn: 1.689 ± 0.457
2.533ProPro: 2.533 ± 0.804
1.126ProGln: 1.126 ± 0.591
3.377ProArg: 3.377 ± 0.631
4.503ProSer: 4.503 ± 0.329
3.377ProThr: 3.377 ± 0.48
3.659ProVal: 3.659 ± 1.265
0.844ProTrp: 0.844 ± 0.407
0.844ProTyr: 0.844 ± 0.929
0.0ProXaa: 0.0 ± 0.0
Gln
1.97GlnAla: 1.97 ± 0.731
0.563GlnCys: 0.563 ± 0.554
1.126GlnAsp: 1.126 ± 0.622
1.689GlnGlu: 1.689 ± 0.295
1.126GlnPhe: 1.126 ± 0.526
2.533GlnGly: 2.533 ± 0.544
1.407GlnHis: 1.407 ± 0.947
2.815GlnIle: 2.815 ± 1.293
2.533GlnLys: 2.533 ± 0.803
1.689GlnLeu: 1.689 ± 0.597
0.844GlnMet: 0.844 ± 0.619
1.97GlnAsn: 1.97 ± 1.088
1.126GlnPro: 1.126 ± 0.699
0.844GlnGln: 0.844 ± 0.332
1.126GlnArg: 1.126 ± 0.39
1.97GlnSer: 1.97 ± 0.782
2.533GlnThr: 2.533 ± 0.575
1.97GlnVal: 1.97 ± 0.715
0.281GlnTrp: 0.281 ± 0.506
1.689GlnTyr: 1.689 ± 0.295
0.0GlnXaa: 0.0 ± 0.0
Arg
1.689ArgAla: 1.689 ± 0.664
1.407ArgCys: 1.407 ± 0.548
2.252ArgAsp: 2.252 ± 0.706
6.755ArgGlu: 6.755 ± 1.405
3.096ArgPhe: 3.096 ± 0.657
4.222ArgGly: 4.222 ± 0.723
1.689ArgHis: 1.689 ± 0.64
3.377ArgIle: 3.377 ± 0.862
2.533ArgLys: 2.533 ± 0.441
3.94ArgLeu: 3.94 ± 1.115
1.689ArgMet: 1.689 ± 0.701
1.97ArgAsn: 1.97 ± 0.755
1.689ArgPro: 1.689 ± 0.502
1.407ArgGln: 1.407 ± 0.668
2.252ArgArg: 2.252 ± 0.467
4.503ArgSer: 4.503 ± 0.719
1.97ArgThr: 1.97 ± 0.391
4.222ArgVal: 4.222 ± 1.171
1.689ArgTrp: 1.689 ± 0.295
1.689ArgTyr: 1.689 ± 0.84
0.0ArgXaa: 0.0 ± 0.0
Ser
3.94SerAla: 3.94 ± 0.77
1.689SerCys: 1.689 ± 0.777
3.377SerAsp: 3.377 ± 0.687
5.629SerGlu: 5.629 ± 1.906
1.97SerPhe: 1.97 ± 0.696
5.629SerGly: 5.629 ± 1.378
1.126SerHis: 1.126 ± 0.563
5.629SerIle: 5.629 ± 0.223
6.755SerLys: 6.755 ± 1.844
8.725SerLeu: 8.725 ± 1.243
1.97SerMet: 1.97 ± 0.609
3.096SerAsn: 3.096 ± 0.31
2.533SerPro: 2.533 ± 0.988
1.97SerGln: 1.97 ± 0.858
4.503SerArg: 4.503 ± 0.981
8.162SerSer: 8.162 ± 2.716
4.785SerThr: 4.785 ± 0.672
6.473SerVal: 6.473 ± 0.753
1.97SerTrp: 1.97 ± 0.522
3.377SerTyr: 3.377 ± 0.591
0.0SerXaa: 0.0 ± 0.0
Thr
2.533ThrAla: 2.533 ± 0.522
0.844ThrCys: 0.844 ± 0.309
3.096ThrAsp: 3.096 ± 0.997
3.377ThrGlu: 3.377 ± 0.505
2.252ThrPhe: 2.252 ± 0.712
4.503ThrGly: 4.503 ± 0.601
2.533ThrHis: 2.533 ± 0.816
4.222ThrIle: 4.222 ± 1.22
2.815ThrLys: 2.815 ± 1.013
5.348ThrLeu: 5.348 ± 1.411
2.533ThrMet: 2.533 ± 0.846
2.252ThrAsn: 2.252 ± 0.453
1.97ThrPro: 1.97 ± 0.944
1.126ThrGln: 1.126 ± 0.622
0.844ThrArg: 0.844 ± 0.466
3.94ThrSer: 3.94 ± 1.234
3.659ThrThr: 3.659 ± 1.296
4.785ThrVal: 4.785 ± 1.179
1.407ThrTrp: 1.407 ± 0.475
3.096ThrTyr: 3.096 ± 1.11
0.0ThrXaa: 0.0 ± 0.0
Val
2.533ValAla: 2.533 ± 2.234
1.126ValCys: 1.126 ± 0.39
5.91ValAsp: 5.91 ± 1.825
4.785ValGlu: 4.785 ± 1.364
3.096ValPhe: 3.096 ± 1.188
3.096ValGly: 3.096 ± 0.639
1.407ValHis: 1.407 ± 0.548
3.659ValIle: 3.659 ± 1.251
3.096ValLys: 3.096 ± 0.86
4.503ValLeu: 4.503 ± 1.361
2.533ValMet: 2.533 ± 0.695
1.407ValAsn: 1.407 ± 0.668
5.348ValPro: 5.348 ± 1.612
1.97ValGln: 1.97 ± 0.435
3.377ValArg: 3.377 ± 0.774
5.348ValSer: 5.348 ± 2.097
2.252ValThr: 2.252 ± 0.337
2.815ValVal: 2.815 ± 1.41
0.844ValTrp: 0.844 ± 0.332
1.689ValTyr: 1.689 ± 0.5
0.0ValXaa: 0.0 ± 0.0
Trp
0.281TrpAla: 0.281 ± 0.357
0.0TrpCys: 0.0 ± 0.0
1.689TrpAsp: 1.689 ± 0.466
3.377TrpGlu: 3.377 ± 1.146
0.563TrpPhe: 0.563 ± 0.311
1.97TrpGly: 1.97 ± 1.016
0.281TrpHis: 0.281 ± 0.155
2.815TrpIle: 2.815 ± 1.032
1.407TrpLys: 1.407 ± 0.341
0.844TrpLeu: 0.844 ± 0.332
0.563TrpMet: 0.563 ± 0.454
0.281TrpAsn: 0.281 ± 0.155
0.563TrpPro: 0.563 ± 0.311
0.844TrpGln: 0.844 ± 0.309
0.0TrpArg: 0.0 ± 0.0
1.126TrpSer: 1.126 ± 0.622
0.563TrpThr: 0.563 ± 0.454
1.689TrpVal: 1.689 ± 0.847
0.0TrpTrp: 0.0 ± 0.0
1.126TrpTyr: 1.126 ± 0.317
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.407TyrAla: 1.407 ± 0.953
1.126TyrCys: 1.126 ± 0.622
0.844TyrAsp: 0.844 ± 0.391
1.126TyrGlu: 1.126 ± 0.502
1.689TyrPhe: 1.689 ± 0.597
3.096TyrGly: 3.096 ± 0.548
1.126TyrHis: 1.126 ± 0.502
1.126TyrIle: 1.126 ± 0.989
2.533TyrLys: 2.533 ± 0.846
5.066TyrLeu: 5.066 ± 0.851
0.844TyrMet: 0.844 ± 0.776
1.97TyrAsn: 1.97 ± 0.799
1.407TyrPro: 1.407 ± 0.422
1.97TyrGln: 1.97 ± 0.709
2.815TyrArg: 2.815 ± 1.594
3.659TyrSer: 3.659 ± 0.913
1.126TyrThr: 1.126 ± 0.39
1.97TyrVal: 1.97 ± 1.168
0.0TyrTrp: 0.0 ± 0.0
0.563TyrTyr: 0.563 ± 0.311
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3554 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski