Amino acid dipepetide frequency for Beet curly top virus (strain California/Logan) (BCTV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.347AlaAla: 3.347 ± 2.33
0.0AlaCys: 0.0 ± 0.0
0.837AlaAsp: 0.837 ± 0.582
0.837AlaGlu: 0.837 ± 0.833
0.837AlaPhe: 0.837 ± 0.833
0.837AlaGly: 0.837 ± 0.703
2.51AlaHis: 2.51 ± 1.199
0.837AlaIle: 0.837 ± 0.959
2.51AlaLys: 2.51 ± 1.747
6.695AlaLeu: 6.695 ± 1.671
1.674AlaMet: 1.674 ± 1.007
3.347AlaAsn: 3.347 ± 2.714
2.51AlaPro: 2.51 ± 0.912
1.674AlaGln: 1.674 ± 1.165
4.184AlaArg: 4.184 ± 2.171
0.837AlaSer: 0.837 ± 0.582
3.347AlaThr: 3.347 ± 1.212
0.837AlaVal: 0.837 ± 0.833
0.837AlaTrp: 0.837 ± 0.703
0.837AlaTyr: 0.837 ± 0.582
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.674CysPhe: 1.674 ± 1.216
0.0CysGly: 0.0 ± 0.0
0.837CysHis: 0.837 ± 0.959
2.51CysIle: 2.51 ± 1.142
1.674CysLys: 1.674 ± 0.925
0.837CysLeu: 0.837 ± 1.055
0.0CysMet: 0.0 ± 0.0
2.51CysAsn: 2.51 ± 1.784
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.837CysArg: 0.837 ± 0.703
1.674CysSer: 1.674 ± 0.925
0.837CysThr: 0.837 ± 0.959
0.837CysVal: 0.837 ± 0.833
0.837CysTrp: 0.837 ± 0.843
0.837CysTyr: 0.837 ± 0.703
0.0CysXaa: 0.0 ± 0.0
Asp
1.674AspAla: 1.674 ± 1.165
0.0AspCys: 0.0 ± 0.0
1.674AspAsp: 1.674 ± 0.728
0.837AspGlu: 0.837 ± 0.582
1.674AspPhe: 1.674 ± 0.968
2.51AspGly: 2.51 ± 1.747
0.0AspHis: 0.0 ± 0.0
2.51AspIle: 2.51 ± 1.856
1.674AspLys: 1.674 ± 0.728
1.674AspLeu: 1.674 ± 0.916
3.347AspMet: 3.347 ± 2.185
5.021AspAsn: 5.021 ± 1.98
2.51AspPro: 2.51 ± 1.325
1.674AspGln: 1.674 ± 1.277
1.674AspArg: 1.674 ± 1.46
3.347AspSer: 3.347 ± 1.625
2.51AspThr: 2.51 ± 0.816
3.347AspVal: 3.347 ± 1.457
1.674AspTrp: 1.674 ± 1.46
1.674AspTyr: 1.674 ± 0.851
0.0AspXaa: 0.0 ± 0.0
Glu
2.51GluAla: 2.51 ± 1.325
1.674GluCys: 1.674 ± 1.919
4.184GluAsp: 4.184 ± 0.803
9.205GluGlu: 9.205 ± 4.096
2.51GluPhe: 2.51 ± 1.72
4.184GluGly: 4.184 ± 1.414
0.0GluHis: 0.0 ± 0.0
3.347GluIle: 3.347 ± 1.826
3.347GluLys: 3.347 ± 1.326
2.51GluLeu: 2.51 ± 1.13
0.837GluMet: 0.837 ± 0.582
2.51GluAsn: 2.51 ± 0.816
0.837GluPro: 0.837 ± 0.843
3.347GluGln: 3.347 ± 1.648
1.674GluArg: 1.674 ± 1.007
5.021GluSer: 5.021 ± 2.51
4.184GluThr: 4.184 ± 2.203
5.021GluVal: 5.021 ± 2.418
2.51GluTrp: 2.51 ± 1.747
0.837GluTyr: 0.837 ± 0.582
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.837PheCys: 0.837 ± 0.582
2.51PheAsp: 2.51 ± 1.308
1.674PheGlu: 1.674 ± 1.686
0.0PhePhe: 0.0 ± 0.0
1.674PheGly: 1.674 ± 0.728
1.674PheHis: 1.674 ± 0.925
1.674PheIle: 1.674 ± 1.104
0.0PheLys: 0.0 ± 0.0
8.368PheLeu: 8.368 ± 2.603
0.0PheMet: 0.0 ± 0.0
3.347PheAsn: 3.347 ± 1.803
2.51PhePro: 2.51 ± 0.963
3.347PheGln: 3.347 ± 1.384
5.858PheArg: 5.858 ± 2.295
2.51PheSer: 2.51 ± 1.302
1.674PheThr: 1.674 ± 0.916
0.837PheVal: 0.837 ± 0.843
0.837PheTrp: 0.837 ± 0.703
1.674PheTyr: 1.674 ± 1.104
0.0PheXaa: 0.0 ± 0.0
Gly
3.347GlyAla: 3.347 ± 1.625
0.0GlyCys: 0.0 ± 0.0
3.347GlyAsp: 3.347 ± 1.625
3.347GlyGlu: 3.347 ± 1.749
0.837GlyPhe: 0.837 ± 0.959
5.858GlyGly: 5.858 ± 2.56
1.674GlyHis: 1.674 ± 0.916
5.021GlyIle: 5.021 ± 1.214
4.184GlyLys: 4.184 ± 1.793
3.347GlyLeu: 3.347 ± 2.037
1.674GlyMet: 1.674 ± 0.961
3.347GlyAsn: 3.347 ± 1.968
4.184GlyPro: 4.184 ± 1.946
3.347GlyGln: 3.347 ± 1.1
0.837GlyArg: 0.837 ± 0.582
5.858GlySer: 5.858 ± 2.621
3.347GlyThr: 3.347 ± 2.218
0.837GlyVal: 0.837 ± 0.582
0.0GlyTrp: 0.0 ± 0.0
0.837GlyTyr: 0.837 ± 0.703
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.674HisGlu: 1.674 ± 0.916
1.674HisPhe: 1.674 ± 0.916
0.0HisGly: 0.0 ± 0.0
1.674HisHis: 1.674 ± 0.916
0.837HisIle: 0.837 ± 0.849
0.837HisLys: 0.837 ± 0.843
4.184HisLeu: 4.184 ± 1.793
0.837HisMet: 0.837 ± 0.849
2.51HisAsn: 2.51 ± 1.747
1.674HisPro: 1.674 ± 0.916
1.674HisGln: 1.674 ± 1.12
1.674HisArg: 1.674 ± 1.231
0.0HisSer: 0.0 ± 0.0
0.837HisThr: 0.837 ± 0.959
2.51HisVal: 2.51 ± 0.928
1.674HisTrp: 1.674 ± 0.728
0.837HisTyr: 0.837 ± 0.959
0.0HisXaa: 0.0 ± 0.0
Ile
0.837IleAla: 0.837 ± 0.582
0.837IleCys: 0.837 ± 0.843
4.184IleAsp: 4.184 ± 1.034
3.347IleGlu: 3.347 ± 1.518
3.347IlePhe: 3.347 ± 1.12
3.347IleGly: 3.347 ± 1.41
1.674IleHis: 1.674 ± 1.231
4.184IleIle: 4.184 ± 1.213
1.674IleLys: 1.674 ± 1.165
5.021IleLeu: 5.021 ± 1.386
0.0IleMet: 0.0 ± 0.0
1.674IleAsn: 1.674 ± 1.007
2.51IlePro: 2.51 ± 0.947
7.531IleGln: 7.531 ± 2.675
5.858IleArg: 5.858 ± 1.699
4.184IleSer: 4.184 ± 2.79
5.021IleThr: 5.021 ± 1.348
1.674IleVal: 1.674 ± 0.728
0.837IleTrp: 0.837 ± 0.703
2.51IleTyr: 2.51 ± 1.799
0.0IleXaa: 0.0 ± 0.0
Lys
1.674LysAla: 1.674 ± 0.728
2.51LysCys: 2.51 ± 1.785
3.347LysAsp: 3.347 ± 1.457
6.695LysGlu: 6.695 ± 1.276
2.51LysPhe: 2.51 ± 1.319
1.674LysGly: 1.674 ± 0.925
2.51LysHis: 2.51 ± 1.116
2.51LysIle: 2.51 ± 1.357
7.531LysLys: 7.531 ± 3.272
4.184LysLeu: 4.184 ± 1.433
2.51LysMet: 2.51 ± 0.816
2.51LysAsn: 2.51 ± 0.816
3.347LysPro: 3.347 ± 0.98
0.837LysGln: 0.837 ± 0.959
3.347LysArg: 3.347 ± 1.388
2.51LysSer: 2.51 ± 1.747
0.837LysThr: 0.837 ± 0.582
6.695LysVal: 6.695 ± 2.396
0.837LysTrp: 0.837 ± 0.703
5.021LysTyr: 5.021 ± 1.992
0.0LysXaa: 0.0 ± 0.0
Leu
0.837LeuAla: 0.837 ± 0.833
0.837LeuCys: 0.837 ± 0.582
2.51LeuAsp: 2.51 ± 0.928
7.531LeuGlu: 7.531 ± 1.998
5.858LeuPhe: 5.858 ± 2.876
4.184LeuGly: 4.184 ± 0.803
4.184LeuHis: 4.184 ± 2.285
3.347LeuIle: 3.347 ± 1.12
10.879LeuLys: 10.879 ± 1.857
5.858LeuLeu: 5.858 ± 1.957
2.51LeuMet: 2.51 ± 1.295
6.695LeuAsn: 6.695 ± 2.185
1.674LeuPro: 1.674 ± 1.46
5.021LeuGln: 5.021 ± 2.11
5.021LeuArg: 5.021 ± 1.707
7.531LeuSer: 7.531 ± 3.05
4.184LeuThr: 4.184 ± 1.879
0.837LeuVal: 0.837 ± 0.582
0.837LeuTrp: 0.837 ± 0.843
5.021LeuTyr: 5.021 ± 2.274
0.0LeuXaa: 0.0 ± 0.0
Met
0.837MetAla: 0.837 ± 0.703
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.837MetGlu: 0.837 ± 0.959
0.0MetPhe: 0.0 ± 0.0
2.51MetGly: 2.51 ± 1.33
0.0MetHis: 0.0 ± 0.0
0.837MetIle: 0.837 ± 0.703
2.51MetLys: 2.51 ± 0.928
1.674MetLeu: 1.674 ± 1.405
0.837MetMet: 0.837 ± 1.055
3.347MetAsn: 3.347 ± 2.014
3.347MetPro: 3.347 ± 1.388
0.837MetGln: 0.837 ± 0.582
1.674MetArg: 1.674 ± 1.405
1.674MetSer: 1.674 ± 1.405
0.837MetThr: 0.837 ± 0.703
1.674MetVal: 1.674 ± 1.46
0.837MetTrp: 0.837 ± 0.582
1.674MetTyr: 1.674 ± 1.405
0.0MetXaa: 0.0 ± 0.0
Asn
2.51AsnAla: 2.51 ± 1.116
1.674AsnCys: 1.674 ± 1.024
2.51AsnAsp: 2.51 ± 0.816
1.674AsnGlu: 1.674 ± 0.728
3.347AsnPhe: 3.347 ± 1.643
2.51AsnGly: 2.51 ± 1.59
1.674AsnHis: 1.674 ± 1.027
3.347AsnIle: 3.347 ± 1.625
1.674AsnLys: 1.674 ± 0.916
7.531AsnLeu: 7.531 ± 2.863
1.674AsnMet: 1.674 ± 1.405
5.021AsnAsn: 5.021 ± 0.999
4.184AsnPro: 4.184 ± 0.897
2.51AsnGln: 2.51 ± 0.928
5.021AsnArg: 5.021 ± 1.95
5.021AsnSer: 5.021 ± 1.704
2.51AsnThr: 2.51 ± 2.108
5.858AsnVal: 5.858 ± 1.885
0.0AsnTrp: 0.0 ± 0.0
5.021AsnTyr: 5.021 ± 1.978
0.0AsnXaa: 0.0 ± 0.0
Pro
2.51ProAla: 2.51 ± 1.534
1.674ProCys: 1.674 ± 0.916
3.347ProAsp: 3.347 ± 1.058
5.021ProGlu: 5.021 ± 1.655
1.674ProPhe: 1.674 ± 1.231
2.51ProGly: 2.51 ± 1.131
0.837ProHis: 0.837 ± 0.582
2.51ProIle: 2.51 ± 1.615
1.674ProLys: 1.674 ± 0.728
5.021ProLeu: 5.021 ± 2.086
1.674ProMet: 1.674 ± 1.024
3.347ProAsn: 3.347 ± 1.388
1.674ProPro: 1.674 ± 0.916
2.51ProGln: 2.51 ± 0.912
4.184ProArg: 4.184 ± 1.544
4.184ProSer: 4.184 ± 2.174
5.021ProThr: 5.021 ± 1.827
0.837ProVal: 0.837 ± 0.703
0.837ProTrp: 0.837 ± 0.582
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.184GlnAla: 4.184 ± 1.68
0.837GlnCys: 0.837 ± 0.582
1.674GlnAsp: 1.674 ± 1.919
1.674GlnGlu: 1.674 ± 0.925
3.347GlnPhe: 3.347 ± 1.647
4.184GlnGly: 4.184 ± 2.171
2.51GlnHis: 2.51 ± 1.131
5.021GlnIle: 5.021 ± 2.24
4.184GlnLys: 4.184 ± 1.04
6.695GlnLeu: 6.695 ± 2.625
0.0GlnMet: 0.0 ± 0.0
0.837GlnAsn: 0.837 ± 0.843
4.184GlnPro: 4.184 ± 1.875
3.347GlnGln: 3.347 ± 1.391
1.674GlnArg: 1.674 ± 0.728
3.347GlnSer: 3.347 ± 2.24
1.674GlnThr: 1.674 ± 1.165
1.674GlnVal: 1.674 ± 1.46
0.837GlnTrp: 0.837 ± 0.703
0.837GlnTyr: 0.837 ± 0.703
0.0GlnXaa: 0.0 ± 0.0
Arg
5.021ArgAla: 5.021 ± 2.266
1.674ArgCys: 1.674 ± 1.034
2.51ArgAsp: 2.51 ± 1.368
3.347ArgGlu: 3.347 ± 1.917
3.347ArgPhe: 3.347 ± 1.663
5.021ArgGly: 5.021 ± 2.729
0.0ArgHis: 0.0 ± 0.0
3.347ArgIle: 3.347 ± 0.704
4.184ArgLys: 4.184 ± 2.123
1.674ArgLeu: 1.674 ± 0.968
0.837ArgMet: 0.837 ± 0.754
2.51ArgAsn: 2.51 ± 2.108
1.674ArgPro: 1.674 ± 0.728
2.51ArgGln: 2.51 ± 1.589
6.695ArgArg: 6.695 ± 3.514
5.021ArgSer: 5.021 ± 1.92
7.531ArgThr: 7.531 ± 2.709
2.51ArgVal: 2.51 ± 1.198
0.837ArgTrp: 0.837 ± 0.833
3.347ArgTyr: 3.347 ± 1.431
0.0ArgXaa: 0.0 ± 0.0
Ser
3.347SerAla: 3.347 ± 0.98
1.674SerCys: 1.674 ± 1.216
2.51SerAsp: 2.51 ± 1.26
0.837SerGlu: 0.837 ± 1.055
0.837SerPhe: 0.837 ± 0.582
2.51SerGly: 2.51 ± 2.36
0.837SerHis: 0.837 ± 0.959
5.858SerIle: 5.858 ± 4.011
3.347SerLys: 3.347 ± 1.326
7.531SerLeu: 7.531 ± 2.498
0.837SerMet: 0.837 ± 0.703
2.51SerAsn: 2.51 ± 0.968
4.184SerPro: 4.184 ± 2.812
5.021SerGln: 5.021 ± 1.862
4.184SerArg: 4.184 ± 2.002
13.389SerSer: 13.389 ± 3.458
10.879SerThr: 10.879 ± 3.711
5.021SerVal: 5.021 ± 3.058
0.837SerTrp: 0.837 ± 0.582
2.51SerTyr: 2.51 ± 1.747
0.0SerXaa: 0.0 ± 0.0
Thr
0.837ThrAla: 0.837 ± 0.582
0.0ThrCys: 0.0 ± 0.0
0.837ThrAsp: 0.837 ± 0.703
3.347ThrGlu: 3.347 ± 2.436
2.51ThrPhe: 2.51 ± 1.26
6.695ThrGly: 6.695 ± 2.827
1.674ThrHis: 1.674 ± 1.064
4.184ThrIle: 4.184 ± 1.057
4.184ThrLys: 4.184 ± 1.811
5.858ThrLeu: 5.858 ± 0.922
2.51ThrMet: 2.51 ± 1.308
6.695ThrAsn: 6.695 ± 1.454
3.347ThrPro: 3.347 ± 1.625
1.674ThrGln: 1.674 ± 1.064
4.184ThrArg: 4.184 ± 1.263
5.858ThrSer: 5.858 ± 2.675
1.674ThrThr: 1.674 ± 1.064
2.51ThrVal: 2.51 ± 1.319
0.837ThrTrp: 0.837 ± 0.849
5.858ThrTyr: 5.858 ± 1.827
0.0ThrXaa: 0.0 ± 0.0
Val
1.674ValAla: 1.674 ± 1.12
0.837ValCys: 0.837 ± 1.055
3.347ValAsp: 3.347 ± 1.792
4.184ValGlu: 4.184 ± 1.185
1.674ValPhe: 1.674 ± 1.034
0.837ValGly: 0.837 ± 0.703
0.0ValHis: 0.0 ± 0.0
4.184ValIle: 4.184 ± 2.66
3.347ValLys: 3.347 ± 1.41
4.184ValLeu: 4.184 ± 1.629
0.0ValMet: 0.0 ± 0.846
3.347ValAsn: 3.347 ± 1.746
2.51ValPro: 2.51 ± 1.142
2.51ValGln: 2.51 ± 0.947
2.51ValArg: 2.51 ± 1.856
5.021ValSer: 5.021 ± 1.933
3.347ValThr: 3.347 ± 2.066
3.347ValVal: 3.347 ± 1.612
0.0ValTrp: 0.0 ± 0.0
2.51ValTyr: 2.51 ± 1.598
0.0ValXaa: 0.0 ± 0.0
Trp
1.674TrpAla: 1.674 ± 1.165
0.837TrpCys: 0.837 ± 0.833
0.0TrpAsp: 0.0 ± 0.0
0.837TrpGlu: 0.837 ± 0.703
0.837TrpPhe: 0.837 ± 0.843
0.837TrpGly: 0.837 ± 0.582
0.0TrpHis: 0.0 ± 0.0
1.674TrpIle: 1.674 ± 1.007
1.674TrpLys: 1.674 ± 0.728
0.837TrpLeu: 0.837 ± 1.055
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.837TrpPro: 0.837 ± 0.703
0.837TrpGln: 0.837 ± 0.582
1.674TrpArg: 1.674 ± 1.405
0.0TrpSer: 0.0 ± 0.0
2.51TrpThr: 2.51 ± 1.199
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.837TrpTyr: 0.837 ± 0.849
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.51TyrAla: 2.51 ± 0.816
0.0TyrCys: 0.0 ± 0.0
1.674TyrAsp: 1.674 ± 0.728
3.347TyrGlu: 3.347 ± 1.148
2.51TyrPhe: 2.51 ± 1.116
3.347TyrGly: 3.347 ± 1.212
0.837TyrHis: 0.837 ± 0.703
2.51TyrIle: 2.51 ± 1.199
2.51TyrLys: 2.51 ± 1.56
1.674TyrLeu: 1.674 ± 0.968
3.347TyrMet: 3.347 ± 1.897
4.184TyrAsn: 4.184 ± 1.899
3.347TyrPro: 3.347 ± 1.411
2.51TyrGln: 2.51 ± 0.968
0.837TyrArg: 0.837 ± 0.703
1.674TyrSer: 1.674 ± 1.302
2.51TyrThr: 2.51 ± 1.52
3.347TyrVal: 3.347 ± 1.41
0.0TyrTrp: 0.0 ± 0.0
2.51TyrTyr: 2.51 ± 1.784
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1196 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski