Amino acid dipepetide frequency for Capsicum annuum (Capsicum pepper)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.342AlaAla: 5.342 ± 0.027	1.186AlaCys: 1.186 ± 0.011	2.92AlaAsp: 2.92 ± 0.017	3.994AlaGlu: 3.994 ± 0.02	2.617AlaPhe: 2.617 ± 0.015	3.717AlaGly: 3.717 ± 0.022	1.225AlaHis: 1.225 ± 0.01	3.708AlaIle: 3.708 ± 0.021	3.89AlaLys: 3.89 ± 0.019	6.163AlaLeu: 6.163 ± 0.026	1.671AlaMet: 1.671 ± 0.011	2.651AlaAsn: 2.651 ± 0.016	2.532AlaPro: 2.532 ± 0.016	1.952AlaGln: 1.952 ± 0.013	3.04AlaArg: 3.04 ± 0.017	5.411AlaSer: 5.411 ± 0.023	3.435AlaThr: 3.435 ± 0.018	4.256AlaVal: 4.256 ± 0.024	0.718AlaTrp: 0.718 ± 0.008	1.855AlaTyr: 1.855 ± 0.013	0.013AlaXaa: 0.013 ± 0.001
Cys	0.98CysAla: 0.98 ± 0.01	0.55CysCys: 0.55 ± 0.007	0.986CysAsp: 0.986 ± 0.009	0.89CysGlu: 0.89 ± 0.01	0.931CysPhe: 0.931 ± 0.01	1.39CysGly: 1.39 ± 0.013	0.513CysHis: 0.513 ± 0.009	1.078CysIle: 1.078 ± 0.009	1.199CysLys: 1.199 ± 0.011	1.917CysLeu: 1.917 ± 0.015	0.447CysMet: 0.447 ± 0.006	0.886CysAsn: 0.886 ± 0.01	0.943CysPro: 0.943 ± 0.01	0.636CysGln: 0.636 ± 0.008	0.997CysArg: 0.997 ± 0.011	1.84CysSer: 1.84 ± 0.014	0.899CysThr: 0.899 ± 0.008	1.052CysVal: 1.052 ± 0.01	0.252CysTrp: 0.252 ± 0.005	0.607CysTyr: 0.607 ± 0.007	0.002CysXaa: 0.002 ± 0.0
Asp	3.292AspAla: 3.292 ± 0.018	1.017AspCys: 1.017 ± 0.009	3.71AspAsp: 3.71 ± 0.024	4.177AspGlu: 4.177 ± 0.023	2.507AspPhe: 2.507 ± 0.016	3.6AspGly: 3.6 ± 0.019	1.228AspHis: 1.228 ± 0.009	3.338AspIle: 3.338 ± 0.018	2.903AspLys: 2.903 ± 0.018	5.43AspLeu: 5.43 ± 0.021	1.426AspMet: 1.426 ± 0.01	2.329AspAsn: 2.329 ± 0.014	2.463AspPro: 2.463 ± 0.017	1.756AspGln: 1.756 ± 0.013	2.238AspArg: 2.238 ± 0.014	4.141AspSer: 4.141 ± 0.02	2.28AspThr: 2.28 ± 0.015	3.974AspVal: 3.974 ± 0.019	0.71AspTrp: 0.71 ± 0.007	1.66AspTyr: 1.66 ± 0.011	0.003AspXaa: 0.003 ± 0.001
Glu	4.346GluAla: 4.346 ± 0.02	0.974GluCys: 0.974 ± 0.008	3.943GluAsp: 3.943 ± 0.023	6.085GluGlu: 6.085 ± 0.048	2.515GluPhe: 2.515 ± 0.015	3.578GluGly: 3.578 ± 0.02	1.281GluHis: 1.281 ± 0.011	4.137GluIle: 4.137 ± 0.02	5.031GluLys: 5.031 ± 0.036	6.139GluLeu: 6.139 ± 0.029	1.848GluMet: 1.848 ± 0.014	3.302GluAsn: 3.302 ± 0.018	1.961GluPro: 1.961 ± 0.015	2.126GluGln: 2.126 ± 0.015	3.182GluArg: 3.182 ± 0.019	4.596GluSer: 4.596 ± 0.024	2.889GluThr: 2.889 ± 0.017	4.373GluVal: 4.373 ± 0.021	0.737GluTrp: 0.737 ± 0.007	1.821GluTyr: 1.821 ± 0.013	0.005GluXaa: 0.005 ± 0.001
Phe	2.377PheAla: 2.377 ± 0.013	0.911PheCys: 0.911 ± 0.01	2.501PheAsp: 2.501 ± 0.013	2.415PheGlu: 2.415 ± 0.015	1.966PhePhe: 1.966 ± 0.015	3.114PheGly: 3.114 ± 0.018	1.157PheHis: 1.157 ± 0.008	2.264PheIle: 2.264 ± 0.015	2.309PheLys: 2.309 ± 0.015	4.491PheLeu: 4.491 ± 0.022	1.033PheMet: 1.033 ± 0.01	1.923PheAsn: 1.923 ± 0.012	2.124PhePro: 2.124 ± 0.014	1.555PheGln: 1.555 ± 0.011	1.933PheArg: 1.933 ± 0.013	4.062PheSer: 4.062 ± 0.022	2.065PheThr: 2.065 ± 0.012	2.812PheVal: 2.812 ± 0.018	0.541PheTrp: 0.541 ± 0.007	1.375PheTyr: 1.375 ± 0.011	0.004PheXaa: 0.004 ± 0.001
Gly	3.591GlyAla: 3.591 ± 0.019	1.274GlyCys: 1.274 ± 0.011	3.262GlyAsp: 3.262 ± 0.016	3.605GlyGlu: 3.605 ± 0.019	3.0GlyPhe: 3.0 ± 0.017	4.735GlyGly: 4.735 ± 0.036	1.508GlyHis: 1.508 ± 0.012	3.727GlyIle: 3.727 ± 0.021	4.147GlyLys: 4.147 ± 0.022	5.869GlyLeu: 5.869 ± 0.021	1.522GlyMet: 1.522 ± 0.011	3.192GlyAsn: 3.192 ± 0.018	2.283GlyPro: 2.283 ± 0.015	1.953GlyGln: 1.953 ± 0.013	3.31GlyArg: 3.31 ± 0.02	5.59GlySer: 5.59 ± 0.027	3.157GlyThr: 3.157 ± 0.016	4.121GlyVal: 4.121 ± 0.02	0.808GlyTrp: 0.808 ± 0.008	2.13GlyTyr: 2.13 ± 0.015	0.008GlyXaa: 0.008 ± 0.001
His	1.328HisAla: 1.328 ± 0.011	0.528HisCys: 0.528 ± 0.007	1.206HisAsp: 1.206 ± 0.01	1.259HisGlu: 1.259 ± 0.011	1.148HisPhe: 1.148 ± 0.01	1.659HisGly: 1.659 ± 0.013	0.903HisHis: 0.903 ± 0.012	1.285HisIle: 1.285 ± 0.012	1.193HisLys: 1.193 ± 0.009	2.547HisLeu: 2.547 ± 0.016	0.574HisMet: 0.574 ± 0.008	1.078HisAsn: 1.078 ± 0.01	1.267HisPro: 1.267 ± 0.01	0.971HisGln: 0.971 ± 0.009	1.259HisArg: 1.259 ± 0.01	1.861HisSer: 1.861 ± 0.013	0.95HisThr: 0.95 ± 0.009	1.541HisVal: 1.541 ± 0.012	0.342HisTrp: 0.342 ± 0.006	0.781HisTyr: 0.781 ± 0.008	0.003HisXaa: 0.003 ± 0.0
Ile	3.65IleAla: 3.65 ± 0.018	1.172IleCys: 1.172 ± 0.01	3.235IleAsp: 3.235 ± 0.015	3.446IleGlu: 3.446 ± 0.018	2.509IlePhe: 2.509 ± 0.015	3.628IleGly: 3.628 ± 0.017	1.435IleHis: 1.435 ± 0.011	3.127IleIle: 3.127 ± 0.017	3.247IleLys: 3.247 ± 0.013	5.69IleLeu: 5.69 ± 0.023	1.283IleMet: 1.283 ± 0.01	2.455IleAsn: 2.455 ± 0.015	3.289IlePro: 3.289 ± 0.026	2.09IleGln: 2.09 ± 0.013	2.679IleArg: 2.679 ± 0.016	5.196IleSer: 5.196 ± 0.023	2.776IleThr: 2.776 ± 0.015	3.764IleVal: 3.764 ± 0.016	0.753IleTrp: 0.753 ± 0.008	1.649IleTyr: 1.649 ± 0.013	0.004IleXaa: 0.004 ± 0.001
Lys	3.939LysAla: 3.939 ± 0.017	1.097LysCys: 1.097 ± 0.011	3.488LysAsp: 3.488 ± 0.017	4.93LysGlu: 4.93 ± 0.025	2.42LysPhe: 2.42 ± 0.015	3.714LysGly: 3.714 ± 0.015	1.396LysHis: 1.396 ± 0.01	3.689LysIle: 3.689 ± 0.017	5.241LysLys: 5.241 ± 0.028	6.484LysLeu: 6.484 ± 0.028	1.698LysMet: 1.698 ± 0.013	3.023LysAsn: 3.023 ± 0.018	2.566LysPro: 2.566 ± 0.02	2.264LysGln: 2.264 ± 0.015	3.591LysArg: 3.591 ± 0.019	4.919LysSer: 4.919 ± 0.027	2.893LysThr: 2.893 ± 0.016	4.177LysVal: 4.177 ± 0.02	0.811LysTrp: 0.811 ± 0.008	1.905LysTyr: 1.905 ± 0.014	0.005LysXaa: 0.005 ± 0.001
Leu	6.19LeuAla: 6.19 ± 0.027	1.865LeuCys: 1.865 ± 0.013	5.439LeuAsp: 5.439 ± 0.019	6.488LeuGlu: 6.488 ± 0.029	3.952LeuPhe: 3.952 ± 0.019	5.81LeuGly: 5.81 ± 0.026	2.573LeuHis: 2.573 ± 0.015	4.983LeuIle: 4.983 ± 0.019	6.643LeuLys: 6.643 ± 0.026	9.861LeuLeu: 9.861 ± 0.036	2.276LeuMet: 2.276 ± 0.013	4.231LeuAsn: 4.231 ± 0.021	5.09LeuPro: 5.09 ± 0.024	4.304LeuGln: 4.304 ± 0.024	5.351LeuArg: 5.351 ± 0.023	8.867LeuSer: 8.867 ± 0.035	4.677LeuThr: 4.677 ± 0.02	6.504LeuVal: 6.504 ± 0.028	1.181LeuTrp: 1.181 ± 0.009	2.728LeuTyr: 2.728 ± 0.017	0.011LeuXaa: 0.011 ± 0.001
Met	1.88MetAla: 1.88 ± 0.013	0.353MetCys: 0.353 ± 0.005	1.51MetAsp: 1.51 ± 0.012	1.952MetGlu: 1.952 ± 0.014	0.886MetPhe: 0.886 ± 0.008	1.565MetGly: 1.565 ± 0.011	0.571MetHis: 0.571 ± 0.006	1.337MetIle: 1.337 ± 0.009	1.806MetLys: 1.806 ± 0.012	2.326MetLeu: 2.326 ± 0.013	0.758MetMet: 0.758 ± 0.01	1.152MetAsn: 1.152 ± 0.01	1.09MetPro: 1.09 ± 0.009	0.962MetGln: 0.962 ± 0.009	1.206MetArg: 1.206 ± 0.01	1.856MetSer: 1.856 ± 0.012	1.188MetThr: 1.188 ± 0.009	1.724MetVal: 1.724 ± 0.012	0.275MetTrp: 0.275 ± 0.005	0.665MetTyr: 0.665 ± 0.008	0.002MetXaa: 0.002 ± 0.0
Asn	2.671AsnAla: 2.671 ± 0.015	0.952AsnCys: 0.952 ± 0.011	2.403AsnAsp: 2.403 ± 0.015	2.817AsnGlu: 2.817 ± 0.017	2.163AsnPhe: 2.163 ± 0.012	3.227AsnGly: 3.227 ± 0.018	1.133AsnHis: 1.133 ± 0.009	2.864AsnIle: 2.864 ± 0.016	2.683AsnLys: 2.683 ± 0.014	5.248AsnLeu: 5.248 ± 0.036	1.234AsnMet: 1.234 ± 0.009	2.772AsnAsn: 2.772 ± 0.024	2.272AsnPro: 2.272 ± 0.015	1.731AsnGln: 1.731 ± 0.015	1.975AsnArg: 1.975 ± 0.013	4.038AsnSer: 4.038 ± 0.024	2.011AsnThr: 2.011 ± 0.013	3.093AsnVal: 3.093 ± 0.017	0.589AsnTrp: 0.589 ± 0.007	1.473AsnTyr: 1.473 ± 0.012	0.004AsnXaa: 0.004 ± 0.0
Pro	2.621ProAla: 2.621 ± 0.018	0.759ProCys: 0.759 ± 0.008	2.314ProAsp: 2.314 ± 0.015	2.967ProGlu: 2.967 ± 0.021	1.961ProPhe: 1.961 ± 0.012	2.409ProGly: 2.409 ± 0.017	1.041ProHis: 1.041 ± 0.01	2.459ProIle: 2.459 ± 0.016	2.83ProLys: 2.83 ± 0.018	4.104ProLeu: 4.104 ± 0.018	0.97ProMet: 0.97 ± 0.01	2.404ProAsn: 2.404 ± 0.015	3.305ProPro: 3.305 ± 0.055	1.695ProGln: 1.695 ± 0.013	2.22ProArg: 2.22 ± 0.015	4.807ProSer: 4.807 ± 0.03	2.528ProThr: 2.528 ± 0.016	2.874ProVal: 2.874 ± 0.016	0.634ProTrp: 0.634 ± 0.009	1.353ProTyr: 1.353 ± 0.013	0.009ProXaa: 0.009 ± 0.001
Gln	2.169GlnAla: 2.169 ± 0.016	0.606GlnCys: 0.606 ± 0.007	1.69GlnAsp: 1.69 ± 0.012	2.373GlnGlu: 2.373 ± 0.015	1.383GlnPhe: 1.383 ± 0.01	1.975GlnGly: 1.975 ± 0.013	0.944GlnHis: 0.944 ± 0.009	2.06GlnIle: 2.06 ± 0.014	2.44GlnLys: 2.44 ± 0.014	3.716GlnLeu: 3.716 ± 0.02	0.952GlnMet: 0.952 ± 0.009	1.863GlnAsn: 1.863 ± 0.013	1.531GlnPro: 1.531 ± 0.013	1.995GlnGln: 1.995 ± 0.024	1.943GlnArg: 1.943 ± 0.013	2.659GlnSer: 2.659 ± 0.014	1.636GlnThr: 1.636 ± 0.012	2.371GlnVal: 2.371 ± 0.015	0.449GlnTrp: 0.449 ± 0.006	0.977GlnTyr: 0.977 ± 0.008	0.004GlnXaa: 0.004 ± 0.001
Arg	2.897ArgAla: 2.897 ± 0.018	0.975ArgCys: 0.975 ± 0.009	2.594ArgAsp: 2.594 ± 0.015	3.178ArgGlu: 3.178 ± 0.018	2.115ArgPhe: 2.115 ± 0.012	2.96ArgGly: 2.96 ± 0.018	1.221ArgHis: 1.221 ± 0.011	2.96ArgIle: 2.96 ± 0.016	3.822ArgLys: 3.822 ± 0.021	4.717ArgLeu: 4.717 ± 0.023	1.309ArgMet: 1.309 ± 0.012	2.484ArgAsn: 2.484 ± 0.014	2.075ArgPro: 2.075 ± 0.013	1.665ArgGln: 1.665 ± 0.013	3.6ArgArg: 3.6 ± 0.025	3.987ArgSer: 3.987 ± 0.017	2.381ArgThr: 2.381 ± 0.014	3.123ArgVal: 3.123 ± 0.017	0.701ArgTrp: 0.701 ± 0.007	1.517ArgTyr: 1.517 ± 0.01	0.007ArgXaa: 0.007 ± 0.001
Ser	4.786SerAla: 4.786 ± 0.022	1.773SerCys: 1.773 ± 0.012	4.374SerAsp: 4.374 ± 0.022	4.665SerGlu: 4.665 ± 0.025	4.04SerPhe: 4.04 ± 0.02	5.601SerGly: 5.601 ± 0.024	1.923SerHis: 1.923 ± 0.013	4.92SerIle: 4.92 ± 0.022	5.143SerLys: 5.143 ± 0.023	8.784SerLeu: 8.784 ± 0.031	2.121SerMet: 2.121 ± 0.013	4.233SerAsn: 4.233 ± 0.022	4.155SerPro: 4.155 ± 0.033	2.91SerGln: 2.91 ± 0.018	4.215SerArg: 4.215 ± 0.02	10.249SerSer: 10.249 ± 0.048	4.77SerThr: 4.77 ± 0.023	5.062SerVal: 5.062 ± 0.022	1.224SerTrp: 1.224 ± 0.01	2.497SerTyr: 2.497 ± 0.016	0.009SerXaa: 0.009 ± 0.001
Thr	3.034ThrAla: 3.034 ± 0.015	0.924ThrCys: 0.924 ± 0.009	2.392ThrAsp: 2.392 ± 0.015	2.739ThrGlu: 2.739 ± 0.015	2.112ThrPhe: 2.112 ± 0.015	3.161ThrGly: 3.161 ± 0.019	1.011ThrHis: 1.011 ± 0.01	3.064ThrIle: 3.064 ± 0.014	2.84ThrLys: 2.84 ± 0.016	4.744ThrLeu: 4.744 ± 0.02	1.186ThrMet: 1.186 ± 0.009	2.292ThrAsn: 2.292 ± 0.013	2.437ThrPro: 2.437 ± 0.018	1.488ThrGln: 1.488 ± 0.01	2.326ThrArg: 2.326 ± 0.015	4.761ThrSer: 4.761 ± 0.019	3.052ThrThr: 3.052 ± 0.018	3.2ThrVal: 3.2 ± 0.02	0.615ThrTrp: 0.615 ± 0.006	1.468ThrTyr: 1.468 ± 0.011	0.005ThrXaa: 0.005 ± 0.001
Val	4.615ValAla: 4.615 ± 0.024	1.145ValCys: 1.145 ± 0.009	3.853ValAsp: 3.853 ± 0.018	4.491ValGlu: 4.491 ± 0.022	2.712ValPhe: 2.712 ± 0.016	4.078ValGly: 4.078 ± 0.022	1.562ValHis: 1.562 ± 0.013	3.659ValIle: 3.659 ± 0.02	4.15ValLys: 4.15 ± 0.017	6.426ValLeu: 6.426 ± 0.025	1.602ValMet: 1.602 ± 0.013	2.825ValAsn: 2.825 ± 0.015	3.104ValPro: 3.104 ± 0.019	2.288ValGln: 2.288 ± 0.013	2.935ValArg: 2.935 ± 0.017	5.214ValSer: 5.214 ± 0.023	3.248ValThr: 3.248 ± 0.016	5.042ValVal: 5.042 ± 0.022	0.736ValTrp: 0.736 ± 0.008	2.058ValTyr: 2.058 ± 0.014	0.006ValXaa: 0.006 ± 0.001
Trp	0.716TrpAla: 0.716 ± 0.008	0.258TrpCys: 0.258 ± 0.006	0.687TrpAsp: 0.687 ± 0.01	0.745TrpGlu: 0.745 ± 0.009	0.565TrpPhe: 0.565 ± 0.006	0.693TrpGly: 0.693 ± 0.008	0.32TrpHis: 0.32 ± 0.006	0.787TrpIle: 0.787 ± 0.008	1.003TrpLys: 1.003 ± 0.008	1.197TrpLeu: 1.197 ± 0.011	0.364TrpMet: 0.364 ± 0.005	0.757TrpAsn: 0.757 ± 0.008	0.463TrpPro: 0.463 ± 0.007	0.409TrpGln: 0.409 ± 0.006	0.8TrpArg: 0.8 ± 0.008	0.982TrpSer: 0.982 ± 0.009	0.635TrpThr: 0.635 ± 0.007	0.763TrpVal: 0.763 ± 0.008	0.233TrpTrp: 0.233 ± 0.005	0.371TrpTyr: 0.371 ± 0.005	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.859TyrAla: 1.859 ± 0.014	0.674TyrCys: 0.674 ± 0.007	1.674TyrAsp: 1.674 ± 0.013	1.647TyrGlu: 1.647 ± 0.012	1.425TyrPhe: 1.425 ± 0.01	2.165TyrGly: 2.165 ± 0.015	0.733TyrHis: 0.733 ± 0.009	1.626TyrIle: 1.626 ± 0.012	1.724TyrLys: 1.724 ± 0.017	3.165TyrLeu: 3.165 ± 0.016	0.788TyrMet: 0.788 ± 0.008	1.499TyrAsn: 1.499 ± 0.011	1.305TyrPro: 1.305 ± 0.012	0.988TyrGln: 0.988 ± 0.009	1.477TyrArg: 1.477 ± 0.01	2.411TyrSer: 2.411 ± 0.015	1.373TyrThr: 1.373 ± 0.011	1.917TyrVal: 1.917 ± 0.014	0.438TyrTrp: 0.438 ± 0.005	1.101TyrTyr: 1.101 ± 0.016	0.002TyrXaa: 0.002 ± 0.0
Xaa	0.011XaaAla: 0.011 ± 0.001	0.003XaaCys: 0.003 ± 0.0	0.003XaaAsp: 0.003 ± 0.0	0.006XaaGlu: 0.006 ± 0.001	0.003XaaPhe: 0.003 ± 0.001	0.011XaaGly: 0.011 ± 0.001	0.003XaaHis: 0.003 ± 0.0	0.005XaaIle: 0.005 ± 0.001	0.005XaaLys: 0.005 ± 0.001	0.009XaaLeu: 0.009 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.008XaaPro: 0.008 ± 0.001	0.003XaaGln: 0.003 ± 0.0	0.008XaaArg: 0.008 ± 0.001	0.008XaaSer: 0.008 ± 0.001	0.006XaaThr: 0.006 ± 0.001	0.006XaaVal: 0.006 ± 0.001	0.002XaaTrp: 0.002 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.306XaaXaa: 0.306 ± 0.026

Statistics based on 35548 proteins (12948852 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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