Amino acid dipepetide frequency for Pacific flying fox faeces associated circular DNA virus-5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.435AlaAla: 5.435 ± 3.487
0.0AlaCys: 0.0 ± 0.0
1.812AlaAsp: 1.812 ± 1.162
5.435AlaGlu: 5.435 ± 3.487
1.812AlaPhe: 1.812 ± 1.175
0.0AlaGly: 0.0 ± 0.0
3.623AlaHis: 3.623 ± 2.324
1.812AlaIle: 1.812 ± 1.162
1.812AlaLys: 1.812 ± 1.162
7.246AlaLeu: 7.246 ± 0.025
0.0AlaMet: 0.0 ± 0.0
3.623AlaAsn: 3.623 ± 0.013
5.435AlaPro: 5.435 ± 1.188
1.812AlaGln: 1.812 ± 1.162
1.812AlaArg: 1.812 ± 1.175
3.623AlaSer: 3.623 ± 0.013
1.812AlaThr: 1.812 ± 1.162
5.435AlaVal: 5.435 ± 1.149
0.0AlaTrp: 0.0 ± 0.0
5.435AlaTyr: 5.435 ± 1.188
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.812CysAsp: 1.812 ± 1.162
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
3.623CysArg: 3.623 ± 2.324
3.623CysSer: 3.623 ± 0.013
3.623CysThr: 3.623 ± 0.013
0.0CysVal: 0.0 ± 0.0
1.812CysTrp: 1.812 ± 1.175
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.435AspAla: 5.435 ± 1.149
1.812AspCys: 1.812 ± 1.175
1.812AspAsp: 1.812 ± 1.162
0.0AspGlu: 0.0 ± 0.0
1.812AspPhe: 1.812 ± 1.175
5.435AspGly: 5.435 ± 1.188
0.0AspHis: 0.0 ± 0.0
3.623AspIle: 3.623 ± 2.35
0.0AspLys: 0.0 ± 0.0
1.812AspLeu: 1.812 ± 1.175
0.0AspMet: 0.0 ± 0.0
1.812AspAsn: 1.812 ± 1.175
1.812AspPro: 1.812 ± 1.175
3.623AspGln: 3.623 ± 0.013
5.435AspArg: 5.435 ± 3.487
3.623AspSer: 3.623 ± 0.013
1.812AspThr: 1.812 ± 1.175
3.623AspVal: 3.623 ± 2.35
5.435AspTrp: 5.435 ± 3.487
1.812AspTyr: 1.812 ± 1.162
0.0AspXaa: 0.0 ± 0.0
Glu
1.812GluAla: 1.812 ± 1.162
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
7.246GluGlu: 7.246 ± 4.649
5.435GluPhe: 5.435 ± 1.188
5.435GluGly: 5.435 ± 3.487
0.0GluHis: 0.0 ± 0.0
7.246GluIle: 7.246 ± 4.649
1.812GluLys: 1.812 ± 1.175
3.623GluLeu: 3.623 ± 2.324
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
3.623GluPro: 3.623 ± 2.35
1.812GluGln: 1.812 ± 1.175
5.435GluArg: 5.435 ± 3.487
1.812GluSer: 1.812 ± 1.162
3.623GluThr: 3.623 ± 2.324
1.812GluVal: 1.812 ± 1.162
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.812PheAla: 1.812 ± 1.175
0.0PheCys: 0.0 ± 0.0
1.812PheAsp: 1.812 ± 1.162
3.623PheGlu: 3.623 ± 2.324
5.435PhePhe: 5.435 ± 1.188
3.623PheGly: 3.623 ± 0.013
0.0PheHis: 0.0 ± 0.0
3.623PheIle: 3.623 ± 0.013
1.812PheLys: 1.812 ± 1.162
0.0PheLeu: 0.0 ± 0.0
1.812PheMet: 1.812 ± 1.175
0.0PheAsn: 0.0 ± 0.0
3.623PhePro: 3.623 ± 2.35
1.812PheGln: 1.812 ± 1.175
3.623PheArg: 3.623 ± 2.35
0.0PheSer: 0.0 ± 0.0
9.058PheThr: 9.058 ± 1.2
1.812PheVal: 1.812 ± 1.162
1.812PheTrp: 1.812 ± 1.175
1.812PheTyr: 1.812 ± 1.175
0.0PheXaa: 0.0 ± 0.0
Gly
5.435GlyAla: 5.435 ± 1.149
1.812GlyCys: 1.812 ± 1.162
3.623GlyAsp: 3.623 ± 0.013
5.435GlyGlu: 5.435 ± 1.149
0.0GlyPhe: 0.0 ± 0.0
12.681GlyGly: 12.681 ± 1.124
3.623GlyHis: 3.623 ± 2.324
3.623GlyIle: 3.623 ± 0.013
3.623GlyLys: 3.623 ± 2.324
3.623GlyLeu: 3.623 ± 2.35
1.812GlyMet: 1.812 ± 0.903
5.435GlyAsn: 5.435 ± 1.188
3.623GlyPro: 3.623 ± 0.013
5.435GlyGln: 5.435 ± 1.149
5.435GlyArg: 5.435 ± 3.487
1.812GlySer: 1.812 ± 1.162
10.87GlyThr: 10.87 ± 2.375
1.812GlyVal: 1.812 ± 1.175
1.812GlyTrp: 1.812 ± 1.175
5.435GlyTyr: 5.435 ± 3.487
0.0GlyXaa: 0.0 ± 0.0
His
1.812HisAla: 1.812 ± 1.162
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.812HisGlu: 1.812 ± 1.175
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.812HisIle: 1.812 ± 1.162
3.623HisLys: 3.623 ± 2.35
1.812HisLeu: 1.812 ± 1.162
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
3.623HisGln: 3.623 ± 0.013
1.812HisArg: 1.812 ± 1.175
5.435HisSer: 5.435 ± 3.525
1.812HisThr: 1.812 ± 1.175
3.623HisVal: 3.623 ± 0.013
1.812HisTrp: 1.812 ± 1.162
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.623IleAla: 3.623 ± 2.324
1.812IleCys: 1.812 ± 1.162
0.0IleAsp: 0.0 ± 0.0
3.623IleGlu: 3.623 ± 2.324
3.623IlePhe: 3.623 ± 2.324
7.246IleGly: 7.246 ± 2.312
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
0.0IleLys: 0.0 ± 0.0
3.623IleLeu: 3.623 ± 0.013
1.812IleMet: 1.812 ± 1.175
1.812IleAsn: 1.812 ± 1.175
7.246IlePro: 7.246 ± 2.362
1.812IleGln: 1.812 ± 1.175
3.623IleArg: 3.623 ± 2.324
3.623IleSer: 3.623 ± 2.35
3.623IleThr: 3.623 ± 0.013
3.623IleVal: 3.623 ± 2.324
0.0IleTrp: 0.0 ± 0.0
1.812IleTyr: 1.812 ± 1.175
0.0IleXaa: 0.0 ± 0.0
Lys
3.623LysAla: 3.623 ± 0.013
0.0LysCys: 0.0 ± 0.0
3.623LysAsp: 3.623 ± 2.324
0.0LysGlu: 0.0 ± 0.0
1.812LysPhe: 1.812 ± 1.162
1.812LysGly: 1.812 ± 1.162
1.812LysHis: 1.812 ± 1.175
0.0LysIle: 0.0 ± 0.0
3.623LysLys: 3.623 ± 2.324
1.812LysLeu: 1.812 ± 1.162
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
1.812LysPro: 1.812 ± 1.175
1.812LysGln: 1.812 ± 1.162
1.812LysArg: 1.812 ± 1.162
5.435LysSer: 5.435 ± 3.487
3.623LysThr: 3.623 ± 0.013
1.812LysVal: 1.812 ± 1.162
5.435LysTrp: 5.435 ± 1.149
3.623LysTyr: 3.623 ± 0.013
0.0LysXaa: 0.0 ± 0.0
Leu
5.435LeuAla: 5.435 ± 1.149
0.0LeuCys: 0.0 ± 0.0
1.812LeuAsp: 1.812 ± 1.162
0.0LeuGlu: 0.0 ± 0.0
3.623LeuPhe: 3.623 ± 0.013
1.812LeuGly: 1.812 ± 1.162
3.623LeuHis: 3.623 ± 0.013
0.0LeuIle: 0.0 ± 0.0
3.623LeuLys: 3.623 ± 2.324
0.0LeuLeu: 0.0 ± 0.0
0.0LeuMet: 0.0 ± 0.0
5.435LeuAsn: 5.435 ± 1.188
5.435LeuPro: 5.435 ± 1.188
5.435LeuGln: 5.435 ± 1.188
3.623LeuArg: 3.623 ± 2.324
0.0LeuSer: 0.0 ± 0.0
1.812LeuThr: 1.812 ± 1.175
3.623LeuVal: 3.623 ± 0.013
3.623LeuTrp: 3.623 ± 2.35
5.435LeuTyr: 5.435 ± 3.525
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
3.623MetGly: 3.623 ± 0.013
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.812MetLys: 1.812 ± 1.175
1.812MetLeu: 1.812 ± 1.175
1.812MetMet: 1.812 ± 1.175
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.812MetThr: 1.812 ± 1.175
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.812AsnAsp: 1.812 ± 1.175
0.0AsnGlu: 0.0 ± 0.0
3.623AsnPhe: 3.623 ± 2.35
3.623AsnGly: 3.623 ± 2.324
0.0AsnHis: 0.0 ± 0.0
5.435AsnIle: 5.435 ± 1.188
1.812AsnLys: 1.812 ± 1.162
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
1.812AsnAsn: 1.812 ± 1.175
0.0AsnPro: 0.0 ± 0.0
1.812AsnGln: 1.812 ± 1.175
1.812AsnArg: 1.812 ± 1.175
3.623AsnSer: 3.623 ± 2.35
1.812AsnThr: 1.812 ± 1.175
7.246AsnVal: 7.246 ± 0.025
0.0AsnTrp: 0.0 ± 0.0
1.812AsnTyr: 1.812 ± 1.175
0.0AsnXaa: 0.0 ± 0.0
Pro
1.812ProAla: 1.812 ± 1.175
1.812ProCys: 1.812 ± 1.162
3.623ProAsp: 3.623 ± 2.35
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
7.246ProGly: 7.246 ± 2.312
1.812ProHis: 1.812 ± 1.175
3.623ProIle: 3.623 ± 2.35
1.812ProLys: 1.812 ± 1.175
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
3.623ProAsn: 3.623 ± 0.013
0.0ProPro: 0.0 ± 0.0
3.623ProGln: 3.623 ± 2.35
1.812ProArg: 1.812 ± 1.175
3.623ProSer: 3.623 ± 0.013
1.812ProThr: 1.812 ± 1.175
1.812ProVal: 1.812 ± 1.162
0.0ProTrp: 0.0 ± 0.0
5.435ProTyr: 5.435 ± 3.525
0.0ProXaa: 0.0 ± 0.0
Gln
5.435GlnAla: 5.435 ± 1.188
0.0GlnCys: 0.0 ± 0.0
1.812GlnAsp: 1.812 ± 1.175
3.623GlnGlu: 3.623 ± 2.324
1.812GlnPhe: 1.812 ± 1.175
7.246GlnGly: 7.246 ± 0.025
0.0GlnHis: 0.0 ± 0.0
1.812GlnIle: 1.812 ± 1.162
0.0GlnLys: 0.0 ± 0.0
9.058GlnLeu: 9.058 ± 5.874
0.0GlnMet: 0.0 ± 0.907
3.623GlnAsn: 3.623 ± 0.013
1.812GlnPro: 1.812 ± 1.175
3.623GlnGln: 3.623 ± 0.013
1.812GlnArg: 1.812 ± 1.162
3.623GlnSer: 3.623 ± 0.013
5.435GlnThr: 5.435 ± 1.188
0.0GlnVal: 0.0 ± 0.0
3.623GlnTrp: 3.623 ± 2.324
7.246GlnTyr: 7.246 ± 4.699
0.0GlnXaa: 0.0 ± 0.0
Arg
1.812ArgAla: 1.812 ± 1.162
0.0ArgCys: 0.0 ± 0.0
1.812ArgAsp: 1.812 ± 1.162
1.812ArgGlu: 1.812 ± 1.162
5.435ArgPhe: 5.435 ± 1.188
3.623ArgGly: 3.623 ± 2.324
1.812ArgHis: 1.812 ± 1.175
5.435ArgIle: 5.435 ± 1.188
5.435ArgLys: 5.435 ± 1.149
3.623ArgLeu: 3.623 ± 2.324
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
0.0ArgPro: 0.0 ± 0.0
7.246ArgGln: 7.246 ± 0.025
7.246ArgArg: 7.246 ± 0.025
0.0ArgSer: 0.0 ± 0.0
1.812ArgThr: 1.812 ± 1.162
5.435ArgVal: 5.435 ± 1.149
3.623ArgTrp: 3.623 ± 0.013
7.246ArgTyr: 7.246 ± 2.312
0.0ArgXaa: 0.0 ± 0.0
Ser
3.623SerAla: 3.623 ± 2.35
0.0SerCys: 0.0 ± 0.0
7.246SerAsp: 7.246 ± 2.362
3.623SerGlu: 3.623 ± 2.324
1.812SerPhe: 1.812 ± 1.175
7.246SerGly: 7.246 ± 2.312
5.435SerHis: 5.435 ± 1.188
3.623SerIle: 3.623 ± 2.324
1.812SerLys: 1.812 ± 1.162
1.812SerLeu: 1.812 ± 1.175
0.0SerMet: 0.0 ± 0.0
1.812SerAsn: 1.812 ± 1.162
0.0SerPro: 0.0 ± 0.0
1.812SerGln: 1.812 ± 1.175
7.246SerArg: 7.246 ± 0.025
7.246SerSer: 7.246 ± 2.362
3.623SerThr: 3.623 ± 2.324
5.435SerVal: 5.435 ± 1.188
0.0SerTrp: 0.0 ± 0.0
1.812SerTyr: 1.812 ± 1.175
0.0SerXaa: 0.0 ± 0.0
Thr
1.812ThrAla: 1.812 ± 1.175
1.812ThrCys: 1.812 ± 1.175
1.812ThrAsp: 1.812 ± 1.175
7.246ThrGlu: 7.246 ± 2.362
3.623ThrPhe: 3.623 ± 2.35
10.87ThrGly: 10.87 ± 2.375
0.0ThrHis: 0.0 ± 0.0
1.812ThrIle: 1.812 ± 1.162
7.246ThrLys: 7.246 ± 4.649
1.812ThrLeu: 1.812 ± 1.162
0.0ThrMet: 0.0 ± 0.0
3.623ThrAsn: 3.623 ± 2.35
1.812ThrPro: 1.812 ± 1.162
9.058ThrGln: 9.058 ± 3.537
0.0ThrArg: 0.0 ± 0.0
7.246ThrSer: 7.246 ± 0.025
9.058ThrThr: 9.058 ± 1.2
0.0ThrVal: 0.0 ± 0.0
3.623ThrTrp: 3.623 ± 0.013
3.623ThrTyr: 3.623 ± 2.35
0.0ThrXaa: 0.0 ± 0.0
Val
5.435ValAla: 5.435 ± 3.487
1.812ValCys: 1.812 ± 1.162
9.058ValAsp: 9.058 ± 1.2
7.246ValGlu: 7.246 ± 2.312
3.623ValPhe: 3.623 ± 2.324
1.812ValGly: 1.812 ± 1.175
0.0ValHis: 0.0 ± 0.0
3.623ValIle: 3.623 ± 0.013
1.812ValLys: 1.812 ± 1.162
1.812ValLeu: 1.812 ± 1.162
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
1.812ValPro: 1.812 ± 1.162
1.812ValGln: 1.812 ± 1.175
1.812ValArg: 1.812 ± 1.162
5.435ValSer: 5.435 ± 1.188
5.435ValThr: 5.435 ± 3.525
1.812ValVal: 1.812 ± 1.162
1.812ValTrp: 1.812 ± 1.162
1.812ValTyr: 1.812 ± 1.175
0.0ValXaa: 0.0 ± 0.0
Trp
1.812TrpAla: 1.812 ± 1.162
0.0TrpCys: 0.0 ± 0.0
1.812TrpAsp: 1.812 ± 1.162
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.812TrpGly: 1.812 ± 1.175
1.812TrpHis: 1.812 ± 1.175
3.623TrpIle: 3.623 ± 2.324
1.812TrpLys: 1.812 ± 1.162
1.812TrpLeu: 1.812 ± 1.162
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.812TrpPro: 1.812 ± 1.175
3.623TrpGln: 3.623 ± 0.013
3.623TrpArg: 3.623 ± 2.35
1.812TrpSer: 1.812 ± 1.162
1.812TrpThr: 1.812 ± 1.175
7.246TrpVal: 7.246 ± 0.025
1.812TrpTrp: 1.812 ± 1.162
1.812TrpTyr: 1.812 ± 1.162
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.812TyrAla: 1.812 ± 1.162
3.623TyrCys: 3.623 ± 0.013
5.435TyrAsp: 5.435 ± 3.525
0.0TyrGlu: 0.0 ± 0.0
3.623TyrPhe: 3.623 ± 0.013
1.812TyrGly: 1.812 ± 1.175
5.435TyrHis: 5.435 ± 3.525
1.812TyrIle: 1.812 ± 1.175
0.0TyrLys: 0.0 ± 0.0
9.058TyrLeu: 9.058 ± 1.2
1.812TyrMet: 1.812 ± 1.175
3.623TyrAsn: 3.623 ± 2.35
3.623TyrPro: 3.623 ± 0.013
3.623TyrGln: 3.623 ± 0.013
1.812TyrArg: 1.812 ± 1.175
3.623TyrSer: 3.623 ± 2.324
1.812TyrThr: 1.812 ± 1.175
1.812TyrVal: 1.812 ± 1.162
1.812TyrTrp: 1.812 ± 1.175
3.623TyrTyr: 3.623 ± 2.35
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (553 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski