Amino acid dipepetide frequency for Gonapodya prolifera (strain JEL478) (Monoblepharis prolifera)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.105AlaAla: 10.105 ± 0.073	1.062AlaCys: 1.062 ± 0.014	4.496AlaAsp: 4.496 ± 0.035	5.223AlaGlu: 5.223 ± 0.037	3.066AlaPhe: 3.066 ± 0.025	6.833AlaGly: 6.833 ± 0.046	2.071AlaHis: 2.071 ± 0.024	4.017AlaIle: 4.017 ± 0.029	4.129AlaLys: 4.129 ± 0.035	8.539AlaLeu: 8.539 ± 0.048	1.987AlaMet: 1.987 ± 0.017	2.775AlaAsn: 2.775 ± 0.021	5.967AlaPro: 5.967 ± 0.048	3.327AlaGln: 3.327 ± 0.029	5.883AlaArg: 5.883 ± 0.044	7.858AlaSer: 7.858 ± 0.041	5.903AlaThr: 5.903 ± 0.041	6.511AlaVal: 6.511 ± 0.037	1.194AlaTrp: 1.194 ± 0.016	1.859AlaTyr: 1.859 ± 0.019	0.005AlaXaa: 0.005 ± 0.001
Cys	1.048CysAla: 1.048 ± 0.014	0.285CysCys: 0.285 ± 0.009	0.655CysAsp: 0.655 ± 0.013	0.607CysGlu: 0.607 ± 0.011	0.51CysPhe: 0.51 ± 0.011	1.081CysGly: 1.081 ± 0.019	0.298CysHis: 0.298 ± 0.008	0.583CysIle: 0.583 ± 0.01	0.471CysLys: 0.471 ± 0.01	1.125CysLeu: 1.125 ± 0.014	0.241CysMet: 0.241 ± 0.006	0.406CysAsn: 0.406 ± 0.009	0.702CysPro: 0.702 ± 0.014	0.375CysGln: 0.375 ± 0.009	0.782CysArg: 0.782 ± 0.012	0.93CysSer: 0.93 ± 0.013	0.746CysThr: 0.746 ± 0.012	0.95CysVal: 0.95 ± 0.015	0.203CysTrp: 0.203 ± 0.007	0.314CysTyr: 0.314 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.115AspAla: 5.115 ± 0.039	0.574AspCys: 0.574 ± 0.01	3.799AspAsp: 3.799 ± 0.036	3.894AspGlu: 3.894 ± 0.034	2.018AspPhe: 2.018 ± 0.023	4.541AspGly: 4.541 ± 0.035	1.137AspHis: 1.137 ± 0.016	2.435AspIle: 2.435 ± 0.024	2.0AspLys: 2.0 ± 0.024	4.817AspLeu: 4.817 ± 0.028	1.121AspMet: 1.121 ± 0.013	1.475AspAsn: 1.475 ± 0.017	3.446AspPro: 3.446 ± 0.029	1.507AspGln: 1.507 ± 0.018	3.122AspArg: 3.122 ± 0.032	3.856AspSer: 3.856 ± 0.029	2.881AspThr: 2.881 ± 0.023	4.453AspVal: 4.453 ± 0.034	0.781AspTrp: 0.781 ± 0.014	1.219AspTyr: 1.219 ± 0.016	0.002AspXaa: 0.002 ± 0.001
Glu	4.996GluAla: 4.996 ± 0.04	0.665GluCys: 0.665 ± 0.011	3.697GluAsp: 3.697 ± 0.033	4.962GluGlu: 4.962 ± 0.052	1.849GluPhe: 1.849 ± 0.019	4.007GluGly: 4.007 ± 0.031	1.278GluHis: 1.278 ± 0.017	2.536GluIle: 2.536 ± 0.023	3.133GluLys: 3.133 ± 0.028	5.153GluLeu: 5.153 ± 0.036	1.441GluMet: 1.441 ± 0.018	1.927GluAsn: 1.927 ± 0.019	2.46GluPro: 2.46 ± 0.026	2.091GluGln: 2.091 ± 0.021	4.509GluArg: 4.509 ± 0.039	4.173GluSer: 4.173 ± 0.032	3.174GluThr: 3.174 ± 0.03	4.068GluVal: 4.068 ± 0.036	0.941GluTrp: 0.941 ± 0.013	1.339GluTyr: 1.339 ± 0.017	0.002GluXaa: 0.002 ± 0.001
Phe	3.184PheAla: 3.184 ± 0.023	0.535PheCys: 0.535 ± 0.01	2.057PheAsp: 2.057 ± 0.022	1.966PheGlu: 1.966 ± 0.024	1.507PhePhe: 1.507 ± 0.017	2.895PheGly: 2.895 ± 0.028	0.881PheHis: 0.881 ± 0.013	1.452PheIle: 1.452 ± 0.019	1.29PheLys: 1.29 ± 0.017	3.44PheLeu: 3.44 ± 0.031	0.662PheMet: 0.662 ± 0.011	1.155PheAsn: 1.155 ± 0.015	2.127PhePro: 2.127 ± 0.022	1.172PheGln: 1.172 ± 0.015	2.032PheArg: 2.032 ± 0.023	2.909PheSer: 2.909 ± 0.026	1.964PheThr: 1.964 ± 0.019	2.691PheVal: 2.691 ± 0.024	0.577PheTrp: 0.577 ± 0.012	0.952PheTyr: 0.952 ± 0.014	0.002PheXaa: 0.002 ± 0.001
Gly	6.872GlyAla: 6.872 ± 0.045	0.891GlyCys: 0.891 ± 0.015	4.064GlyAsp: 4.064 ± 0.032	3.953GlyGlu: 3.953 ± 0.033	2.589GlyPhe: 2.589 ± 0.024	7.758GlyGly: 7.758 ± 0.06	1.603GlyHis: 1.603 ± 0.021	3.123GlyIle: 3.123 ± 0.026	3.642GlyLys: 3.642 ± 0.029	5.685GlyLeu: 5.685 ± 0.035	1.689GlyMet: 1.689 ± 0.019	2.425GlyAsn: 2.425 ± 0.023	3.456GlyPro: 3.456 ± 0.026	2.332GlyGln: 2.332 ± 0.023	4.799GlyArg: 4.799 ± 0.038	6.249GlySer: 6.249 ± 0.036	4.623GlyThr: 4.623 ± 0.036	5.592GlyVal: 5.592 ± 0.037	1.362GlyTrp: 1.362 ± 0.017	1.873GlyTyr: 1.873 ± 0.024	0.003GlyXaa: 0.003 ± 0.001
His	1.991HisAla: 1.991 ± 0.021	0.32HisCys: 0.32 ± 0.008	1.069HisAsp: 1.069 ± 0.017	1.086HisGlu: 1.086 ± 0.016	0.905HisPhe: 0.905 ± 0.011	1.593HisGly: 1.593 ± 0.017	0.846HisHis: 0.846 ± 0.015	1.105HisIle: 1.105 ± 0.016	0.801HisLys: 0.801 ± 0.012	2.438HisLeu: 2.438 ± 0.023	0.441HisMet: 0.441 ± 0.009	0.686HisAsn: 0.686 ± 0.012	1.973HisPro: 1.973 ± 0.024	0.816HisGln: 0.816 ± 0.013	1.557HisArg: 1.557 ± 0.019	1.938HisSer: 1.938 ± 0.022	1.342HisThr: 1.342 ± 0.016	1.698HisVal: 1.698 ± 0.018	0.303HisTrp: 0.303 ± 0.008	0.545HisTyr: 0.545 ± 0.01	0.002HisXaa: 0.002 ± 0.001
Ile	4.206IleAla: 4.206 ± 0.025	0.599IleCys: 0.599 ± 0.01	2.24IleAsp: 2.24 ± 0.021	2.333IleGlu: 2.333 ± 0.021	1.627IlePhe: 1.627 ± 0.02	2.894IleGly: 2.894 ± 0.026	1.01IleHis: 1.01 ± 0.014	1.874IleIle: 1.874 ± 0.022	1.73IleLys: 1.73 ± 0.021	4.024IleLeu: 4.024 ± 0.037	0.851IleMet: 0.851 ± 0.012	1.356IleAsn: 1.356 ± 0.014	2.955IlePro: 2.955 ± 0.026	1.437IleGln: 1.437 ± 0.018	2.482IleArg: 2.482 ± 0.021	3.422IleSer: 3.422 ± 0.028	2.444IleThr: 2.444 ± 0.024	3.311IleVal: 3.311 ± 0.029	0.517IleTrp: 0.517 ± 0.009	0.979IleTyr: 0.979 ± 0.015	0.002IleXaa: 0.002 ± 0.0
Lys	3.8LysAla: 3.8 ± 0.035	0.481LysCys: 0.481 ± 0.009	2.447LysAsp: 2.447 ± 0.025	3.165LysGlu: 3.165 ± 0.029	1.383LysPhe: 1.383 ± 0.018	2.971LysGly: 2.971 ± 0.028	0.925LysHis: 0.925 ± 0.013	1.882LysIle: 1.882 ± 0.02	2.794LysLys: 2.794 ± 0.033	3.817LysLeu: 3.817 ± 0.03	0.997LysMet: 0.997 ± 0.015	1.37LysAsn: 1.37 ± 0.017	2.35LysPro: 2.35 ± 0.025	1.486LysGln: 1.486 ± 0.018	3.38LysArg: 3.38 ± 0.03	3.204LysSer: 3.204 ± 0.028	2.457LysThr: 2.457 ± 0.023	3.027LysVal: 3.027 ± 0.028	0.664LysTrp: 0.664 ± 0.01	1.126LysTyr: 1.126 ± 0.015	0.003LysXaa: 0.003 ± 0.001
Leu	8.7LeuAla: 8.7 ± 0.044	1.223LeuCys: 1.223 ± 0.017	5.001LeuAsp: 5.001 ± 0.032	5.405LeuGlu: 5.405 ± 0.038	3.211LeuPhe: 3.211 ± 0.027	5.969LeuGly: 5.969 ± 0.036	2.266LeuHis: 2.266 ± 0.021	3.353LeuIle: 3.353 ± 0.029	3.865LeuLys: 3.865 ± 0.032	8.586LeuLeu: 8.586 ± 0.047	1.674LeuMet: 1.674 ± 0.018	2.838LeuAsn: 2.838 ± 0.026	6.131LeuPro: 6.131 ± 0.041	3.268LeuGln: 3.268 ± 0.032	6.07LeuArg: 6.07 ± 0.041	7.747LeuSer: 7.747 ± 0.038	5.021LeuThr: 5.021 ± 0.033	6.214LeuVal: 6.214 ± 0.035	1.135LeuTrp: 1.135 ± 0.015	2.075LeuTyr: 2.075 ± 0.022	0.005LeuXaa: 0.005 ± 0.001
Met	2.055MetAla: 2.055 ± 0.02	0.265MetCys: 0.265 ± 0.006	1.271MetAsp: 1.271 ± 0.015	1.359MetGlu: 1.359 ± 0.017	0.693MetPhe: 0.693 ± 0.012	1.524MetGly: 1.524 ± 0.019	0.424MetHis: 0.424 ± 0.009	0.77MetIle: 0.77 ± 0.012	0.892MetLys: 0.892 ± 0.013	1.713MetLeu: 1.713 ± 0.019	0.519MetMet: 0.519 ± 0.01	0.672MetAsn: 0.672 ± 0.011	1.144MetPro: 1.144 ± 0.015	0.748MetGln: 0.748 ± 0.013	1.258MetArg: 1.258 ± 0.014	1.778MetSer: 1.778 ± 0.02	1.172MetThr: 1.172 ± 0.015	1.354MetVal: 1.354 ± 0.016	0.308MetTrp: 0.308 ± 0.007	0.499MetTyr: 0.499 ± 0.011	0.001MetXaa: 0.001 ± 0.001
Asn	2.991AsnAla: 2.991 ± 0.021	0.395AsnCys: 0.395 ± 0.009	1.554AsnAsp: 1.554 ± 0.018	1.641AsnGlu: 1.641 ± 0.018	1.187AsnPhe: 1.187 ± 0.016	2.797AsnGly: 2.797 ± 0.026	0.714AsnHis: 0.714 ± 0.011	1.586AsnIle: 1.586 ± 0.018	1.188AsnLys: 1.188 ± 0.015	3.099AsnLeu: 3.099 ± 0.027	0.659AsnMet: 0.659 ± 0.012	1.104AsnAsn: 1.104 ± 0.017	2.393AsnPro: 2.393 ± 0.023	1.063AsnGln: 1.063 ± 0.016	1.789AsnArg: 1.789 ± 0.017	2.344AsnSer: 2.344 ± 0.022	1.8AsnThr: 1.8 ± 0.019	2.528AsnVal: 2.528 ± 0.023	0.461AsnTrp: 0.461 ± 0.01	0.818AsnTyr: 0.818 ± 0.014	0.002AsnXaa: 0.002 ± 0.001
Pro	6.044ProAla: 6.044 ± 0.05	0.535ProCys: 0.535 ± 0.012	3.157ProAsp: 3.157 ± 0.022	3.239ProGlu: 3.239 ± 0.032	2.153ProPhe: 2.153 ± 0.02	4.085ProGly: 4.085 ± 0.032	1.643ProHis: 1.643 ± 0.024	2.461ProIle: 2.461 ± 0.023	2.389ProLys: 2.389 ± 0.021	5.418ProLeu: 5.418 ± 0.038	0.999ProMet: 0.999 ± 0.014	2.216ProAsn: 2.216 ± 0.022	7.538ProPro: 7.538 ± 0.11	2.28ProGln: 2.28 ± 0.021	3.757ProArg: 3.757 ± 0.031	7.194ProSer: 7.194 ± 0.052	4.954ProThr: 4.954 ± 0.035	4.097ProVal: 4.097 ± 0.03	0.693ProTrp: 0.693 ± 0.011	1.324ProTyr: 1.324 ± 0.017	0.005ProXaa: 0.005 ± 0.001
Gln	2.802GlnAla: 2.802 ± 0.025	0.433GlnCys: 0.433 ± 0.01	1.549GlnAsp: 1.549 ± 0.019	1.91GlnGlu: 1.91 ± 0.023	1.136GlnPhe: 1.136 ± 0.015	2.313GlnGly: 2.313 ± 0.024	0.871GlnHis: 0.871 ± 0.013	1.564GlnIle: 1.564 ± 0.019	1.576GlnLys: 1.576 ± 0.018	3.146GlnLeu: 3.146 ± 0.031	0.812GlnMet: 0.812 ± 0.012	1.28GlnAsn: 1.28 ± 0.016	2.208GlnPro: 2.208 ± 0.027	1.786GlnGln: 1.786 ± 0.032	2.386GlnArg: 2.386 ± 0.022	2.841GlnSer: 2.841 ± 0.025	2.103GlnThr: 2.103 ± 0.022	2.103GlnVal: 2.103 ± 0.019	0.484GlnTrp: 0.484 ± 0.01	0.895GlnTyr: 0.895 ± 0.016	0.002GlnXaa: 0.002 ± 0.0
Arg	5.539ArgAla: 5.539 ± 0.036	0.805ArgCys: 0.805 ± 0.013	3.65ArgAsp: 3.65 ± 0.03	4.124ArgGlu: 4.124 ± 0.039	2.151ArgPhe: 2.151 ± 0.018	4.538ArgGly: 4.538 ± 0.041	1.53ArgHis: 1.53 ± 0.018	2.858ArgIle: 2.858 ± 0.023	3.412ArgLys: 3.412 ± 0.029	5.592ArgLeu: 5.592 ± 0.037	1.44ArgMet: 1.44 ± 0.018	2.175ArgAsn: 2.175 ± 0.021	3.601ArgPro: 3.601 ± 0.032	2.145ArgGln: 2.145 ± 0.021	5.534ArgArg: 5.534 ± 0.042	5.21ArgSer: 5.21 ± 0.035	3.869ArgThr: 3.869 ± 0.029	4.246ArgVal: 4.246 ± 0.029	1.025ArgTrp: 1.025 ± 0.014	1.438ArgTyr: 1.438 ± 0.017	0.002ArgXaa: 0.002 ± 0.001
Ser	7.745SerAla: 7.745 ± 0.045	0.868SerCys: 0.868 ± 0.013	4.289SerAsp: 4.289 ± 0.036	3.927SerGlu: 3.927 ± 0.032	3.035SerPhe: 3.035 ± 0.026	6.34SerGly: 6.34 ± 0.04	2.099SerHis: 2.099 ± 0.022	3.404SerIle: 3.404 ± 0.022	3.322SerLys: 3.322 ± 0.033	7.617SerLeu: 7.617 ± 0.042	1.5SerMet: 1.5 ± 0.016	2.719SerAsn: 2.719 ± 0.022	6.441SerPro: 6.441 ± 0.053	2.823SerGln: 2.823 ± 0.026	5.325SerArg: 5.325 ± 0.039	9.416SerSer: 9.416 ± 0.066	6.051SerThr: 6.051 ± 0.04	5.316SerVal: 5.316 ± 0.03	1.105SerTrp: 1.105 ± 0.013	1.757SerTyr: 1.757 ± 0.018	0.005SerXaa: 0.005 ± 0.001
Thr	5.622ThrAla: 5.622 ± 0.044	0.767ThrCys: 0.767 ± 0.015	2.794ThrAsp: 2.794 ± 0.021	2.856ThrGlu: 2.856 ± 0.028	2.335ThrPhe: 2.335 ± 0.021	4.342ThrGly: 4.342 ± 0.034	1.366ThrHis: 1.366 ± 0.017	2.747ThrIle: 2.747 ± 0.025	2.388ThrLys: 2.388 ± 0.024	5.8ThrLeu: 5.8 ± 0.034	1.118ThrMet: 1.118 ± 0.016	1.927ThrAsn: 1.927 ± 0.02	4.893ThrPro: 4.893 ± 0.04	1.94ThrGln: 1.94 ± 0.021	3.419ThrArg: 3.419 ± 0.026	6.022ThrSer: 6.022 ± 0.042	4.658ThrThr: 4.658 ± 0.052	4.257ThrVal: 4.257 ± 0.03	0.833ThrTrp: 0.833 ± 0.013	1.392ThrTyr: 1.392 ± 0.02	0.003ThrXaa: 0.003 ± 0.001
Val	6.931ValAla: 6.931 ± 0.037	0.941ValCys: 0.941 ± 0.013	4.201ValAsp: 4.201 ± 0.029	4.665ValGlu: 4.665 ± 0.036	2.533ValPhe: 2.533 ± 0.023	5.329ValGly: 5.329 ± 0.036	1.579ValHis: 1.579 ± 0.019	2.758ValIle: 2.758 ± 0.025	3.036ValLys: 3.036 ± 0.028	6.352ValLeu: 6.352 ± 0.037	1.429ValMet: 1.429 ± 0.017	2.147ValAsn: 2.147 ± 0.022	4.471ValPro: 4.471 ± 0.032	2.401ValGln: 2.401 ± 0.021	4.306ValArg: 4.306 ± 0.031	5.18ValSer: 5.18 ± 0.036	4.011ValThr: 4.011 ± 0.028	5.946ValVal: 5.946 ± 0.039	1.043ValTrp: 1.043 ± 0.015	1.585ValTyr: 1.585 ± 0.021	0.004ValXaa: 0.004 ± 0.001
Trp	1.115TrpAla: 1.115 ± 0.012	0.277TrpCys: 0.277 ± 0.007	0.921TrpAsp: 0.921 ± 0.013	0.858TrpGlu: 0.858 ± 0.014	0.547TrpPhe: 0.547 ± 0.01	1.018TrpGly: 1.018 ± 0.014	0.31TrpHis: 0.31 ± 0.007	0.717TrpIle: 0.717 ± 0.013	0.758TrpLys: 0.758 ± 0.013	1.141TrpLeu: 1.141 ± 0.017	0.37TrpMet: 0.37 ± 0.008	0.602TrpAsn: 0.602 ± 0.012	0.545TrpPro: 0.545 ± 0.011	0.42TrpGln: 0.42 ± 0.008	1.041TrpArg: 1.041 ± 0.015	1.128TrpSer: 1.128 ± 0.015	0.954TrpThr: 0.954 ± 0.014	0.889TrpVal: 0.889 ± 0.014	0.336TrpTrp: 0.336 ± 0.009	0.384TrpTyr: 0.384 ± 0.009	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.946TyrAla: 1.946 ± 0.02	0.391TyrCys: 0.391 ± 0.01	1.281TyrAsp: 1.281 ± 0.018	1.229TyrGlu: 1.229 ± 0.013	1.014TyrPhe: 1.014 ± 0.015	1.754TyrGly: 1.754 ± 0.019	0.604TyrHis: 0.604 ± 0.011	1.062TyrIle: 1.062 ± 0.018	0.908TyrLys: 0.908 ± 0.013	2.248TyrLeu: 2.248 ± 0.022	0.466TyrMet: 0.466 ± 0.01	0.857TyrAsn: 0.857 ± 0.013	1.379TyrPro: 1.379 ± 0.018	0.783TyrGln: 0.783 ± 0.013	1.45TyrArg: 1.45 ± 0.017	1.701TyrSer: 1.701 ± 0.019	1.347TyrThr: 1.347 ± 0.015	1.593TyrVal: 1.593 ± 0.017	0.362TyrTrp: 0.362 ± 0.008	0.737TyrTyr: 0.737 ± 0.014	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.004XaaAla: 0.004 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.004XaaAsp: 0.004 ± 0.001	0.002XaaGlu: 0.002 ± 0.001	0.002XaaPhe: 0.002 ± 0.001	0.002XaaGly: 0.002 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.004XaaIle: 0.004 ± 0.001	0.002XaaLys: 0.002 ± 0.001	0.005XaaLeu: 0.005 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.002XaaAsn: 0.002 ± 0.001	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.003XaaSer: 0.003 ± 0.001	0.003XaaThr: 0.003 ± 0.001	0.006XaaVal: 0.006 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.295XaaXaa: 0.295 ± 0.045

Statistics based on 13801 proteins (5698899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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